Displaying drugs 1 - 25 of 491 in total
Arnica montana flower
Arnica montana flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Arnica Flower (Arnica Montana) ... Arnica Flower (Arnica Montana L.) ... Arnica Montana Oil …
Matched Name: … Arnica montana flower …
Matched Description: … Arnica montana flower is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... DOCTOR HOYS Arnica Boost …
Matched Products: … Arnica Tct ... Naturland Arnica Cream …
Matched Name: … Arnica montana flower …
Matched Description: … Arnica montana flower is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... DOCTOR HOYS Arnica Boost …
Matched Products: … Arnica Tct ... Naturland Arnica Cream …
Belladonna
Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in the nightshade family Solanaceae. Its roots, leaves and fruits contain DB00424, DB00747, and mostly, DB00572. These alkaloids are naturally-occurring muscarinic antagonists. DB00572 is a non-selective muscarinic antagonist that is mainly used as an adjunct for...
Approved
Experimental
Matched Synonyms: … Atropa belladona ... Atropa belladonna …
Matched Name: … Belladonna …
Matched Description: … Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in ... Belladonna is a poisonous plant and belladonna intoxication from accidental ingestion may result in a ... The name "belladonna" originates from the Italian words "beautiful woman" and the historical use of herb …
Matched Mixtures name: … Belladonna and Opium ... Belladonna and Opium ... Belladonna and Opium …
Matched Products: … Belladone Tct ... EKSTRAK BELLADON …
Matched Name: … Belladonna …
Matched Description: … Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in ... Belladonna is a poisonous plant and belladonna intoxication from accidental ingestion may result in a ... The name "belladonna" originates from the Italian words "beautiful woman" and the historical use of herb …
Matched Mixtures name: … Belladonna and Opium ... Belladonna and Opium ... Belladonna and Opium …
Matched Products: … Belladone Tct ... EKSTRAK BELLADON …
Chenopodium album pollen
Chenopodium album pollen is the pollen of the Chenopodium album plant. Chenopodium album pollen is mainly used in allergenic testing.
Approved
Matched Name: … Chenopodium album pollen …
Matched Description: … Chenopodium album pollen is the pollen of the Chenopodium album plant. ... Chenopodium album pollen is mainly used in allergenic testing. …
Matched Products: … Pollens - Weeds and Garden Plants, Lamb Quarters Chenopodium album ... Pollens - Weeds and Garden Plants, Lambs Quarters Chenopodium album ... Chenopodium Album Pollen …
Matched Description: … Chenopodium album pollen is the pollen of the Chenopodium album plant. ... Chenopodium album pollen is mainly used in allergenic testing. …
Matched Products: … Pollens - Weeds and Garden Plants, Lamb Quarters Chenopodium album ... Pollens - Weeds and Garden Plants, Lambs Quarters Chenopodium album ... Chenopodium Album Pollen …
Nitric Oxide
Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power...
Approved
Matched Description: … It is also a toxic air pollutant produced by automobile engines and power plants. ... This gas is an important signaling molecule in the body of mammals including humans and is an extremely …
Matched Categories: … Nitrates and Nitrites …
Matched Products: … Top NO Doctors (Helps improve matabolic disorder, Bean sprout powder) ... Top NO Care Ultra (Helps improve matabolic disorder, Lettuce fermented powder) ... Cabbage Extract, Mesoporous Silica Nanoparticle Zinc Gold) …
Matched Categories: … Nitrates and Nitrites …
Matched Products: … Top NO Doctors (Helps improve matabolic disorder, Bean sprout powder) ... Top NO Care Ultra (Helps improve matabolic disorder, Lettuce fermented powder) ... Cabbage Extract, Mesoporous Silica Nanoparticle Zinc Gold) …
Albumin human
Human serum albumin is the primary protein present in human blood plasma. The main function of albumin is to maintain the oncotic pressure of blood . It binds to water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4) and pharmaceuticals (including barbiturates). Albumin represents approximately...
Approved
Matched Synonyms: … Albumin human ... Albumin (human) ... Albumin, blood …
Matched Name: … Albumin human …
Matched Description: … There are various preparations of albumin that are well established and widely available in the clinical ... This is a biosimilar drug to existing human serum albumin and was approved for a biological license at ... ) and pharmaceuticals (including barbiturates). …
Matched Mixtures name: … Albumin Human Diluent …
Matched Categories: … albumin ... Serum Albumin ... Human Serum Albumin ... Blood and Related Products ... Blood and Blood Forming Organs …
Matched Products: … AlbuRx ... Alburx ... AlbuRx 5, Human Albumin 5% Solution …
Matched Name: … Albumin human …
Matched Description: … There are various preparations of albumin that are well established and widely available in the clinical ... This is a biosimilar drug to existing human serum albumin and was approved for a biological license at ... ) and pharmaceuticals (including barbiturates). …
Matched Mixtures name: … Albumin Human Diluent …
Matched Categories: … albumin ... Serum Albumin ... Human Serum Albumin ... Blood and Related Products ... Blood and Blood Forming Organs …
Matched Products: … AlbuRx ... Alburx ... AlbuRx 5, Human Albumin 5% Solution …
Atropine
Atropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active.[A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. Oral atropine is only available...
Approved
Vet approved
Matched International brands: … Atropt ... AtroPen ... Atrospan …
Matched Synonyms: … Atropin ... Atropina …
Matched Description: … Atropine is an alkaloid originally synthesized from Atropa belladonna. ... , subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. ... It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active …
Matched Mixtures name: … Phenobarbital With Belladonna Alkaloids ... Phenobarbital With Belladonna Alkaloids ... Phenobarbital with Belladonna Alkaloids …
Matched Categories: … Belladonna and Derivatives, Plain ... Alimentary Tract and Metabolism ... Mydriatics and Cycloplegics ... atropine and psycholeptics ... Belladonna Alkaloids …
Matched Products: … ATROPISA ... ATROPINA SOLFATO ... ATROPINA FARMIGEA …
Matched Synonyms: … Atropin ... Atropina …
Matched Description: … Atropine is an alkaloid originally synthesized from Atropa belladonna. ... , subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. ... It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active …
Matched Mixtures name: … Phenobarbital With Belladonna Alkaloids ... Phenobarbital With Belladonna Alkaloids ... Phenobarbital with Belladonna Alkaloids …
Matched Categories: … Belladonna and Derivatives, Plain ... Alimentary Tract and Metabolism ... Mydriatics and Cycloplegics ... atropine and psycholeptics ... Belladonna Alkaloids …
Matched Products: … ATROPISA ... ATROPINA SOLFATO ... ATROPINA FARMIGEA …
Camphor
Camphor is a bicyclic monoterpene ketone found widely in plants, especially Cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity. The FDA...
Approved
Withdrawn
Matched Description: … It is used topically as a skin antipruritic and as an anti-infective agent. ... When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often ... The FDA ruled that camphorated oil could not be marketed in the United States and that no product could …
Matched Mixtures name: … GOLD FISH BRAND MEDICATED OIL ... Arnica Ice Cooling ... Gold Edition Ultra Zheng Gu Shui …
Matched Categories: … Basic Lotions and Liniments ... Antipruritics and Local Anesthetics …
Matched Products: … Muscle and Joint HRX Pain Relieving ... Joints and Muscles Pain Relieving ... Earths Care Muscle and Joint Rub …
Matched Mixtures name: … GOLD FISH BRAND MEDICATED OIL ... Arnica Ice Cooling ... Gold Edition Ultra Zheng Gu Shui …
Matched Categories: … Basic Lotions and Liniments ... Antipruritics and Local Anesthetics …
Matched Products: … Muscle and Joint HRX Pain Relieving ... Joints and Muscles Pain Relieving ... Earths Care Muscle and Joint Rub …
Allantoin
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Description: … Allantoin is a substance that is endogenous to the human body and also found as a normal component of ... During exercise, the plasma allantoin concentration rapidly increases about two fold and remains elevated ... , in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions [A32213]. …
Matched Mixtures name: … Phen-oris - Ont Top ... AL0040600 Alba Cooling Aloe Burn Relief ... Red Ginseng Snail Gold Serum …
Matched Categories: … Herbs and Natural Products ... Basic Ointments and Protectants …
Matched Products: … Zims Advanced Acemannan and Arnica ... Soothex - Crm Top 1% ... Nano Gold Bio Mask Pack …
Matched Mixtures name: … Phen-oris - Ont Top ... AL0040600 Alba Cooling Aloe Burn Relief ... Red Ginseng Snail Gold Serum …
Matched Categories: … Herbs and Natural Products ... Basic Ointments and Protectants …
Matched Products: … Zims Advanced Acemannan and Arnica ... Soothex - Crm Top 1% ... Nano Gold Bio Mask Pack …
Colloidal oatmeal
Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal material. It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity. Colloidal oatmeal...
Approved
Nutraceutical
Matched Description: … Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal ... It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. ... skin irritation and itching due to rashes, eczema, poison ivy, oak, sumac, or insect bites. …
Matched Mixtures name: … Dermavive Shower and Bath Oil …
Matched Products: … AL0043600 Alba Botanica VE Herbal Healing Body ... Phyllis Golden Hair ... Phyllis Golden Hair Essence …
Matched Mixtures name: … Dermavive Shower and Bath Oil …
Matched Products: … AL0043600 Alba Botanica VE Herbal Healing Body ... Phyllis Golden Hair ... Phyllis Golden Hair Essence …
Menthol
Approved
Matched Mixtures name: … Topco 4x Medicated Toothache and Gum Gel ... AL0040600 Alba Cooling Aloe Burn Relief ... Top Medicated …
Matched Products: … Top Care Medicated ... Zims Arnica Max ... Arnica Pain Relief …
Matched Products: … Top Care Medicated ... Zims Arnica Max ... Arnica Pain Relief …
Hydroquinone
Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … As a result of these concerns, hydroquinone has been banned in the EU and UK. ... Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration ... with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and …
Matched Mixtures name: … Top White ... Top White Skin Lightening ... OLIVIA QUIDO FIRM and FADE I …
Matched Products: … ALBUS ... Gold Cosmetics Adi Clear ... Gold Cosmetics Bleach Cream …
Matched Mixtures name: … Top White ... Top White Skin Lightening ... OLIVIA QUIDO FIRM and FADE I …
Matched Products: … ALBUS ... Gold Cosmetics Adi Clear ... Gold Cosmetics Bleach Cream …
Arnica montana
Arnica montana is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Synonyms: … Arnica (Arnica Montana) ... Arnica Tincture ... Arnica Flower Oil …
Matched Name: … Arnica montana …
Matched Description: … Arnica montana is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Products: … Arnica Performance Gel …
Matched Name: … Arnica montana …
Matched Description: … Arnica montana is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Products: … Arnica Performance Gel …
Human Embryonic Stem Cell-derived M Cell
CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. These cells are currently being investigated against lung injury and fibrosis -- conditions which are...
Investigational
Matched Synonyms: … immunity- and matrix-regulatory cells ... Immunity-and-matrix-regulatory cells …
Matched Description: … anti-fibrotic functions, and being stronger in potential treatment of lung injury and fibrosis. ... CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can ... These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. …
Matched Description: … anti-fibrotic functions, and being stronger in potential treatment of lung injury and fibrosis. ... CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can ... These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. …
Vayarin
Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. Vayarin is currently available only...
Approved
Investigational
Matched Synonyms: … Phosphatidylserine, DHA, and EPA …
Matched Description: … Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
Matched Description: … Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
Chloroxylenol
Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Description: … disinfection and surgical instruments. ... Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin ... It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … Gold and Sudsy ... GOJO Gold and Klean Antimicrobial Ltn Sp ... HACCP Flat Top E-2 …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … Gold and Sudsy ... GOJO Gold and Klean Antimicrobial Ltn Sp ... HACCP Flat Top E-2 …
Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized ... allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... developed as an alternative to autografting - the process by which a patient's own skin is harvested and …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... developed as an alternative to autografting - the process by which a patient's own skin is harvested and …
EDIT-301
EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2).
Investigational
Matched Synonyms: … Autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the HBG1 and HBG2 ... ) at the HBG1 and HBG2 promoters ... autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/Cas12a ribonucleoprotein (RNP …
Matched Description: … cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2). ... EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …
Matched Description: … cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2). ... EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …
Synthetic camphor
Approved
Experimental
Matched Mixtures name: … Golden Cup Balm 1950 ... Shelo NABEL Pomada Arnica ... NEW AMMELTZ YOKO YOKO GOLD TOPICAL LIQUID …
Matched Products: … Sanar - Arnica Roll On ... Soothe and Move Pain Relief Cream ... Arthritis and Joint Pain Relief Thayers …
Matched Products: … Sanar - Arnica Roll On ... Soothe and Move Pain Relief Cream ... Arthritis and Joint Pain Relief Thayers …
Petrolatum
A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Synonyms: … Paraffinum album …
Matched Description: … It is used as an ointment base, topical protectant, and lubricant. …
Matched Mixtures name: … Gold Bond Ultimate Diabetics ... Ice Lipbalm - Stk Top ... Ice Lipbalm SPF 12- Stk Top …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Gold Bond Ultimate Cracked Skin Fill and Protect ... Gold Bond Medicated Cracked Skin Fill and Protect ... Gold Bond Medicated Advanced Healing …
Matched Description: … It is used as an ointment base, topical protectant, and lubricant. …
Matched Mixtures name: … Gold Bond Ultimate Diabetics ... Ice Lipbalm - Stk Top ... Ice Lipbalm SPF 12- Stk Top …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Gold Bond Ultimate Cracked Skin Fill and Protect ... Gold Bond Medicated Cracked Skin Fill and Protect ... Gold Bond Medicated Advanced Healing …
MM-111
MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Synonyms: … Antibody bispecific for erbb2 and erbb3 ... Bispecific her2/her3 antibody albumin fusion protein …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
SP1049C
SP1049C is a novel anthracycline chemotherapeutic agent containing doxorubicin and two nonionic pluronic block copolymers. It is designed to overcome drug resistance in a number of cancers. It has successfully completed Phase 1 trials. Phase 2 results are currently under final review. Preliminary data, in its first clinically tested indication,...
Investigational
Matched Synonyms: … doxorubicin with pluronics F-127 and L-61 ... Doxorubicin HCl with pluronic L-61 and pluronic F-127 …
Matched Description: … Median survival is encouraging and correlates strongly with dose levels.[A260416] ... SP1049C is a novel anthracycline chemotherapeutic agent containing [doxorubicin] and two nonionic pluronic …
Matched Description: … Median survival is encouraging and correlates strongly with dose levels.[A260416] ... SP1049C is a novel anthracycline chemotherapeutic agent containing [doxorubicin] and two nonionic pluronic …
Glycerin
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Description: … A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. …
Matched Mixtures name: … Snail Solu Tion Gold ... Red Ginseng Snail Gold Serum ... Medi SM 24K Gold Hydrogel Peptide Mask Pack …
Matched Categories: … Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Other Cold and Cough Preparations …
Matched Products: … Eros Extended Love 2 Top Level ... Eros Extended Love 3 Top Level ... Eros Extended Love 1 Top Level …
Matched Mixtures name: … Snail Solu Tion Gold ... Red Ginseng Snail Gold Serum ... Medi SM 24K Gold Hydrogel Peptide Mask Pack …
Matched Categories: … Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Other Cold and Cough Preparations …
Matched Products: … Eros Extended Love 2 Top Level ... Eros Extended Love 3 Top Level ... Eros Extended Love 1 Top Level …
NeuroCell-PD
Investigational
Matched Synonyms: … Porcine fetal neural dopaminergic cells and/or precursors aseptically prepared and coated with anti-MHC …
PlasmaCord
PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental blood. It is developed by Cellpraxis and is currently being investigated against severe acute respiratory syndrome (SARS).
Investigational
Matched Synonyms: … Human umbilical cord and placental blood plasma …
Matched Description: … PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental ... [L27581] It is developed by Cellpraxis and is currently being investigated against severe acute respiratory …
Matched Description: … PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental ... [L27581] It is developed by Cellpraxis and is currently being investigated against severe acute respiratory …
Displaying drugs 1 - 25 of 491 in total