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Displaying drugs 1 - 25 of 12439 in total
Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome.
Approved
Investigational
Matched Synonyms: … Indium In 111 Pentreotide ... Indium In 111 pentetreotide ... Indium In-111 pentetreotide …
Matched Name: … Indium In-111 pentetreotide …
Matched Iupac: … ]-6,12,15,18-tetrahydroxy-7-(1-hydroxyethyl)-13-[(1H-indol-3-yl)methyl]-9-oxido-1,2-dithia-5,8,11,14,17 ... (111In)indium(3+) ion 2-{[2-({[(1-{[10-(4-aminobutyl)-16-benzyl-4-[(1,3-dihydroxybutan-2-yl)-C-hydroxycarbonimidoyl …
Matched Description: … Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS …
Mitapivat is a novel, first-in-class pyruvate kinase activator. It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival of red blood cells. Defects in the pyruvate kinase enzyme in various red blood cells disorders lead to the lack of energy production for red...
Approved
Investigational
Matched Synonyms: … Pkr-in-1
Matched Iupac: … N-{4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl}quinoline-8-sulfonamide …
Matched Description: … Defects in the pyruvate kinase enzyme in various red blood cells disorders lead to the lack of energy ... It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival ... [A245478] On February 17, 2022, the FDA approved mitapivat as the first disease-modifying treatment …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bos taurus skin or pelt is used in allergenic testing.
Approved
Matched Synonyms: … domestic cow skin extract …
Matched Description: … Bos taurus skin or pelt is used in allergenic testing. …
Capra hircus skin or pelt is used in allergenic testing.
Approved
Matched Synonyms: … domestic goat skin extract …
Matched Description: … Capra hircus skin or pelt is used in allergenic testing. …
Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Synonyms: … Hepatitis B Surface Antigen (rDNA) …
Matched Description: … A significant reduction in the incidence of hepatocellular carcinoma has been observed in children aged ... Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. ... In Canada, the United States and Northern Europe, 4% to 6% of the population are infected during their …
Matched Salts cas: … 351186-51-1
Matched Mixtures name: … HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... TWINRIX ERİŞKİN IM 1 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR ... HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Matched Products: … HEPAVAX-GENE TF INJ. ... ENGERIX-B 20 Mikrogramm/1 ml Injektionssuspension in einer Fertigspritze ... วัคซีนป้องกันโรคตับอักเสบบี (rDNA) สำหรับเด็ก …
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … (CYS74>SER,ALA245>THR)ADENOSINE DEAMINASE (BOS TAURUS, BOVINE)-(1-356)-PEPTIDE, PRODUCED IN ESCHERICHIA ... COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ON N6 OF LYSYL RESIDUES (K) WITH AN ... ),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, EC=3.5.4.4)-(1- …
Matched Description: … can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in ... cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … RECOMBINANT DNA DERIVED B-DOMAIN DELETED PORCINE BLOODCOAGULATION FACTOR VIII ANALOGUE, PRODUCED IN BHK21 …
Matched Description: … Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the activated ... the treatment's efficacy and safety by measuring factor VIII activity levels in addition to clinical …
Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84 amino-acids...
Approved
Investigational
Matched Synonyms: … Parathyroid hormone (rDNA) ... PTH(1-84) ... rPTH(1-84) …
Matched Description: … Preotact is used in the treatment of osteoporosis in postmenopausal women at high risk of osteoporotic ... fractures and is marketed in Europe by Nycomed. ... The name Preos and the New Drug Application is pending approval by the U.S. …
Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Approved
Investigational
Matched Synonyms: … Lenograstim rDNA
Matched Products: … GRANOCYTE 34 MU ENJEKSİYONLUK/İNFÜZYONLUK LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …
Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by Zaire ebolavirus in adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease....
Approved
Matched Synonyms: … (G) replaced with the Zaire Ebola Virus (ZEBOV) Kikwit 1995 strain surface glycoprotein (GP) ... Recombinant Vesicular Stomatitis Virus (rVSV) strain Indiana with a deletion of the VSV envelope glycoprotein …
Matched Description: … In December 2019, Ervebo was approved by the FDA in the United States. ... in Sub-Saharan Africa, where Ebola first appeared in 1976 near the Ebola River in Zaire (presently referred ... adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. …
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediated gene
Matched Description: … [L49231] It is the first CRISPR-based gene editing therapy to be approved in the United States. ... It was approved by the FDA in December 2023 for the treatment of patients with SCD with recurrent vaso-occlusive ... [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease …
Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … Insulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune ... 1 and Type 2 Diabetes. ... reaction that destroys the beta cells of the pancreas, resulting in the body not being able to produce …
Matched Mixtures name: … RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … RapiLog Insulin Aspart Injection (rDNA origin) 100 U/mL ... NOVORAPİD 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... RapiLog One Insulin Aspart Injection (rDNA Origin) 100U/mL, Pre-filled Pen …
Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only...
Approved
Investigational
Matched Description: … calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. ... Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the ... The antibody is produced utlilizing recombinant DNA technology in Chinese hamster ovary cells [FDA Label …
Matched Categories: … Calcitonin Gene-Related Peptide (CGRP) Antagonists ... Calcitonin Gene-Related Peptide Receptor Antagonists …
Matched Products: … KUZELVA 70 MG ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 70MG/ML ... AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 140MG/ML …
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Description: … Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell ... [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region ... Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton …
Matched Products: … BENEPALI 50MG IN FER ... BENEPALI 25MG ILO IN FER ... ERELZI 25MG ILO IN FER …
Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … Insulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune ... Type 1 and Type 2 Diabetes. ... reaction that destroys the beta cells of the pancreas, resulting in the body not being able to produce …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … APIDRA 100 U/ML- SOLUTION FOR INJECTION IN VIAL ... APIDRA 100 Units/ml Solution for Injection in vial ... APIDRA SOLOSTAR 100 UNITS/ML, SOLUTION FOR INJECTION IN A PRE-FILLED PEN …
Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP). Although several small-molecule CGRP receptor antagonists have been developed, humanized monoclonal antibodies like galcanezumab are specifically designed to selectively bind to CGRP entities with high potency. Given this target specificity, lack of...
Approved
Investigational
Matched Description: … [A33112] Galcanezumab was approved by the FDA in September 2018, and is indicated for the preventive ... A pregnancy exposure registry has been established to evaluate the safety of this drug in pregnant women ... Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related …
Matched Categories: … Calcitonin Gene-Related Peptide (CGRP) Antagonists ... Calcitonin Gene-Related Peptide Receptor Antagonists …
Matched Products: … EMGALİTY 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET ... EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED PEN 120 MG/ML ... Pontevia 120 mg solution for injection in pre-filled pen …
Evolocumab is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen. It is a subcutaneous injection approved by the FDA for individuals on maximum statin therapy who still require additional LDL-cholesterol lowering. It is approved for both homozygous and heterozygous familial cholesterolemia as an adjunct to other first-line...
Approved
Matched Description: … surface, resulting in more LDL receptors on the surface of the liver to remove LDL-C from the blood. ... Evolocumab is the second PCSK9 inhibitor on the market, first being alirocumab. ... to remove LDL-cholesterol (LDL-C), or "bad" cholesterol, from the blood. …
Matched Products: … REPATHA 140 MG/ML SC ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET ... REPATHA 140 MG/ML SC ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR KALEM, 1 ADET ... REPATHA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 140MG/ML …
Aflibercept is a recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors, VEGFR1 and VEGFR2, fused with the Fc region of human immunoglobulin gamma 1 (IgG1). Structurally, Aflibercept is a dimeric glycoprotein with a protein molecular weight of 96.9 kilo Daltons (kDa). It...
Approved
Matched Description: … gamma 1 (IgG1). ... the treatment of retinopathy of prematurity in preterm infants in February 2023 and for the treatment ... [L47976] An aflibercept biosimilar, Yesafili, was approved for use in the EU in September 2023. …
Matched Products: … ZALTRAP 100MG/4ML INFUZYONLUK KONSANTRE COZELTI İÇEREN FLAKON, 1 ADET ... EYLEA 40 MG/ML INTRAVITREAL ENJEKSIYON ICIN COZELTI ICEREN FLAKON, 1 ADET ... EYLEA 40MG/ML SOLUTION FOR INJECTION IN VIAL …
Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor.[A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA. This drug is frequently known as Humira. It is produced...
Approved
Experimental
Matched Description: … [A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA. ... Adalimumab-atto was the first adalimumab biosimilar approved by the FDA in 2016. ... - which was approved in August 2022 -,[L42935] and adalimumab-aacf - which was approved in October 2023 …
Matched Products: … AMGEVİTA 40 MG/0.8 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM (1 ADET) ... AMGEVİTA 40 MG/0.8 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR (1 ADET) ... AMGEVİTA 20 MG/0.4 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Tick-borne encephalitis (TBE) is a disease caused by the TBE virus (TBEV), transmitted by ticks from the genus Ixodes. The disease course is variable. Some patients will be asymptomatic or experience a mild febrile illness, while others will experience the full course including neurological symptoms. TBE often manifests in a...
Approved
Matched Description: … and then propagated in chicken embryo fibroblast (CEF) cells, since the 1990's, the whole process has ... in Europe, first approved in 1976. ... the genus _Ixodes_. …
Matched Products: … FSME-Immun 0,25 ml Junior Injektionssuspension in einer Fertigspritze ... FSME-Immun 0,5 ml Erwachsene Injektionssuspension in einer Fertigspritze …
Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. Tinzaparin is composed of molecules with and without a special site for high affinity binding...
Approved
Matched Description: … This complex greatly accelerates the inhibition of factor Xa. …
Matched Products: … innohep 8.000 IE/0,4 ml Injektionslösung in einer Fertigspritze ... innohep 10.000 IE/0,5 ml Injektionslösung in einer Fertigspritze ... innohep 12.000 IE/0,6 ml Injektionslösung in einer Fertigspritze …
Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Description: … in the optic nerve, spinal cord, brainstem, and cerebrum. ... Satralizumab was first approved for use in Canada in June 2020 for the treatment of AQP4 antibody-positive ... by the FDA in August 2020,[L15566] becoming the 3rd treatment to receive FDA approval for NMOSD (after …
Matched Products: … ENSPRYNG 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... ENSPRYNG SOLUTION FOR INJECTION IN PREFILLED SYRINGE 120MG/1ML ... ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringe …
Iron deficiency is an extremely common condition and is the most frequent cause of anemia worldwide. Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately support production of erythrocytes, also known as red blood cells. Though it is generally considered non...
Approved
Matched Description: … [A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. ... Ferric derisomaltose was developed by Pharmacosmos Therapeutics ad was granted FDA approval in January ... trials show that it is non-inferior to [iron sucrose], another form of iron that is often administered in
Matched Products: … Monofer 100 mg/ml solution for injection/infusion in vials ... Monofer 100mg/ml solution for injection/infusion in ampoules …
Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions. In particular, IL-17A has...
Approved
Investigational
Matched Description: … protein backbone of the molecule. ... In particular, IL-17A has been found to be implicated in a variety of autoimmune diseases including Rheumatoid ... effect is beneficial for use in inflammatory conditions. …
Matched Products: … Taltz 80mg solution for injection in pre-filled pen ... Taltz 80mg solution for injection in pre-filled syringe ... TALTZ SOLUTION FOR INJECTION IN PRE-FILLED PEN 80 mg/ml …
Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MIRCERA 360 MCG/0.6 ML SC/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... MIRCERA 100 MCG/ML SC/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... MIRCERA SOLUTION FOR INJECTION IN PRE FILLED SYRINGE, 200MCG/0.3ML …
Displaying drugs 1 - 25 of 12439 in total