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Displaying drugs 276 - 300 of 15294 in total

Streptococcus pneumoniae type 33f capsular polysaccharide antigen

Streptococcus pneumoniae type 33f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 33f of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 33f capsular polysaccharide antigen is a vaccine that contains highly purified ... It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease …
Matched Mixtures name: … PNEUMOVAX 23 Injektionslösung in einer Fertigspritze ... PNEUMOVAX 23 Injektionslösung in einer Durchstechflasche …

Influenza B virus B/Phuket/3073/2013 hemagglutinin antigen (UV, formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …

Norfloxacin

A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Approved
Matched Synonyms: … 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsäure ... 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Filgrastim

Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched International brands: … White-C …
Matched Description: … the sequence for expression in _E. ... Filgrastim mimics the biological actions of G-CSF to increase the levels of neutrophils in the blood. ... L36325] Filgrastim-sndz was approved on March 6, 2015 [L40768] and filgrastim-ayow was approved on March 2, …
Matched Products: … ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML ... ACCOFIL 30 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 30 MU/0.5 ML ... ACCOFIL 48 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 48 MU/0.5 ML …

Influenza A virus A/South Australia/55/2014 (H3N2) hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/South Australia/55/2014 (H3N2) hemagglutinin antigen (MDCK cell derived, propiolactone …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …

Ingenol mebutate

Ingenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. Picato gel is indicated for the topical treatment of actinic keratosis. Before approval, ingenol mebutate was called PEP005 as an investigational drug. PEP005 is a selective small molecule activator of protein kinase...
Approved
Matched Synonyms: … 3-Angeloylingenol ... 3-Ingenyl angelate ... Ingenol 3-angelate …
Matched Iupac: … methylbut-2-enoate ... hydroxymethyl)-3,11,11,14-tetramethyl-15-oxotetracyclo[7.5.1.0^{1,5}.0^{10,12}]pentadeca-2,7-dien-4-yl (2Z)-2- …
Matched Description: … PEP005 is a selective small molecule activator of protein kinase C (PKC) extracted from the plant Euphorbia ... peplus, whose sap has been used as a traditional medicine for the treatment of skin conditions including ... Picato gel is indicated for the topical treatment of actinic keratosis. …

Antihemophilic factor, human recombinant

Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Categories: … Hemophilia A …
Matched Products: … ADVATE 250IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 500IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 1000IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Ranibizumab

Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology ... In order to improve drug delivery to the target organ, ranibizumab is available for intravitreal use. ... BYOOVIZ, a biosimilar of LUCENTIS, was approved by Health Canada in March 2022, making it the first and …
Matched Products: … LUCENTIS 10 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE ... LUCENTIS SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 1.65mg/0.165ml ... Lucentis 10mg/ml Solution for Injection …

Tocilizumab

Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Tocilizumab was granted FDA approval on 8 January 2010 to treat a...
Approved
Matched Description: … [L12789] It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing ... [L44483] Tocilizumab-bavi, a biosimilar drug, was approved by the FDA in September 2023.[L48385] ... Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory …
Matched Categories: … Agents reducing cytokine levels ... Biologics for Rheumatoid Arthritis Treatment ... Experimental Unapproved Treatments for COVID-19 …
Matched Products: … ACTEMRA (162 MG SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE) ... ACTEMRA 162MG/0.9ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE ... Actemra 162mg Solution for Injection in Pre-filled Syringe 162mg/0.9ml …

Coagulation Factor IX (Recombinant)

Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Description: … Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric ... use as a pharmaceutical agent. ... cell line that secretes recombinant Factor IX into cell medium that is then processed and purified for …
Matched Products: … OCTANINE® F 500 UI ... OCTANINE F ® 250 UI ... OCTANINE F 250 U.I. …

Racephedrine

Approved
Experimental
Matched Iupac: … (1S,2R)-2-(methylamino)-1-phenylpropan-1-ol …

Iron

A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron...
Approved
Matched International brands: … Ed-In-Sol ... Fer-In-Sol …
Matched Description: … A metallic element found in certain minerals, in nearly all soils, and in mineral waters. ... Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms ... Iron is used to build up the blood in anemia. …
Matched Mixtures name: … For-2 ... Nephron FA ... Nephron FA …
Matched Products: … FER-IN-SOL ... VENOFER SOLUTION FOR INJECTION 100 mg/5 ml ... FERİMAX 100 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 5 AMPUL …

Aldesleukin

Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … Interleukin-2(2-133),125-ser ... 125-L-serine-2-133-interleukin 2 (human reduced) ... Interleukin-2 aldesleukin …
Matched Description: … This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not ... for this amino acid was deleted during the genetic engineering procedure; c) the molecule has serine ... Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E …
Matched Products: … PROLEUKIN POWDER FOR INFUSION 18 miu/vial …

Glofitamab

Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells.[L45698,A258488] Glofitamab was approved...
Approved
Investigational
Matched Description: … It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting ... Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface ... [L45698,A258488] Glofitamab was approved by Health Canada in March 2023 for the treatment of certain …

Clostridium tetani toxoid antigen (formaldehyde inactivated)

Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus. The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium sulfate filtration...
Approved
Matched Description: … Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection ... The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium ... It is used for active immunization of children 7 years of age or older, and adults, for prevention of …
Matched Mixtures name: … 3 ANTIGEN ... Neisvac-C ... -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE …
Matched Categories: … Antiinfectives for Systemic Use …
Matched Products: … TETAVAX single dose, suspension for injection in a prefilled syringe …

Fluorodopa (18F)

Fluorodopa F 18 is a fluorinated analog of levodopa used as a diagnostic agent for positron emission tomography (PET) in the evaluation of Parkinsonian syndromes. Fluorodopa F 18 PET is used adjunctly with other diagnostic investigations and serves primarily to visualize dopaminergic nerve terminals in the striatum.
Approved
Experimental
Matched Synonyms: … Fluorodopa F-18 …
Matched Iupac: … (2S)-2-amino-3-[2-(¹⁸F)fluoro-4,5-dihydroxyphenyl]propanoic acid …
Matched Description: … Fluorodopa F 18 is a fluorinated analog of [levodopa] used as a diagnostic agent for positron emission ... tomography (PET) in the evaluation of Parkinsonian syndromes. ... to visualize dopaminergic nerve terminals in the striatum. …

Hyoscyamine

Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Matched Synonyms: … [3(S)-endo]-α-(hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester …
Matched Iupac: … (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2S)-3-hydroxy-2-phenylpropanoate …
Matched Description: … [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic ... Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. ... [A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family. …
Matched Mixtures name: … Utira-C ... Utira-C ... UR N-C Urinary Antiseptic …
Matched Categories: … Drugs for Functional Gastrointestinal Disorders …

Ibuprofen

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched International brands: … Act-3 …
Matched Synonyms: … (±)-2-(p-isobutylphenyl)propionic acid ... 2-(4-isobutylphenyl)propanoic acid ... (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid …
Matched Iupac: … 2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … was in 1960 while researching for a safer alternative for aspirin. ... [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... in the UK in 1969 and USA in 1974. …
Matched Mixtures name: … Doc in the Box All Day Supply ... Ibuprofen Cold and Sinus A P J ... BUFEDOL® F …
Matched Categories: … COX-2 Inhibitors ... Non COX-2 selective NSAIDS ... Topical Products for Joint and Muscular Pain ... Experimental Unapproved Treatments for COVID-19 ... Antiinflammatory Products for Vaginal Administration …
Matched Products: … ZOFEN F/C TABLET 200 MG ... PADUCAS 20 MG/2 ML I.V. İNFÜZYONLUK ÇÖZELTİ, 3 ADET ... DUKTAFEN 20 MG/2 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ, 3 ADET …

Triptorelin

Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Iupac: … ]-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl ... ]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-( ... 1H-indol-3-yl)propanamido]-4-methylpentanamide ... (2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl …
Matched Description: … Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. ... Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH) ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Salts cas: … 124508-66-3 …
Matched Products: … Triptofem 0,1 mg/ml Injektionslösung in einer Fertigspritze ... Decapeptyl Depot - Retardmikrokapseln und Suspensionsmittel in Einmalspritzen ... Pamorelin Powder for Suspension for Injection 3.75 mg …

Somatotropin

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Description: … that contains 191 amino acid residues with a molecular weight of 22 kDa. ... [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone ... [A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults …
Matched Products: … GENOTROPIN C ... GROWTROPINAQ 16 U /2 ML INYECTABLE ... SciTropin A Solution for Injection 5 mg/1.5 ml …

Romosozumab

Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant to other osteoperosis therapies . Romosozumab prevents bone resorption and induces the formation of bone though it is associated...
Approved
Investigational
Matched Description: … In a comparison study of post menopausal women with osteoporosis and a past fracture, romosozumab for ... Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal ... Romosozumab also demonstrates a faster and larger increase in bone density than teriparatide[A177050] …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML ... EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17ML ... EVENİTY 105 MG/1,17 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADET …

Betibeglogene autotemcel

Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene (βA-T87Q-globin) to hematopoietic stem cells in order to treat β-thalassemia. β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a significant decrease in the production of β-globin. This affects...
Approved
Investigational
Matched Description: … [L42940] BB305 LVV encodes βA-T87Q-globin, compensating for the lack of β-globin in these ... This affects hemoglobin levels, and in patients with severe forms of this disease, long-term red cell ... [L42940] β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a …

Thioridazine

A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Synonyms: … 3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine ... 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine ... 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine …
Matched Iupac: … 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine …
Matched Description: … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the ... Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal ... Thioridazine was withdrawn worldwide in 2005 due to its association with cardiac arrythmias. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Novo-ridazine (thioridazine Oral Suspension) - 2 mg/ml …

Albutrepenonacog alfa

Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It was also approved by FDA and EMA in 2016. ... Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …

Ergometrine

An ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Approved
Matched Synonyms: … N-(2-Hydroxy-1-methylethyl)-D-(+)-lysergamide ... 9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8β(S)-carboxamide ... [8β(S)]-9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8-carboxamide …
Matched Iupac: … (4R,7R)-N-[(2S)-1-hydroxypropan-2-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca- …
Displaying drugs 276 - 300 of 15294 in total