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Displaying drugs 576 - 600 of 15295 in total

Risdiplam

Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). It increases systemic SMN protein concentrations by improving the efficiency of SMN2 gene transcription. This mechanism of action is similar to its predecessor nusinersen, the biggest difference being their route of administration: nusinersen...
Approved
Investigational
Matched Iupac: … 7-{4,7-diazaspiro[2.5]octan-7-yl}-2-{2,8-dimethylimidazo[1,2-b]pyridazin-6-yl}-4H-pyrido[1,2-a]pyrimidin …
Matched Description: … [L15351,A216871] Risdiplam was approved by the FDA in August 2020 for the treatment of spinal muscular ... to be substantially cheaper than other available SMA therapies,[L15351] risdiplam appears to provide a ... Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular …
Matched Categories: … MATE 2 Inhibitors ... Survival of Motor Neuron 2 Splicing Modifier ... Survival Motor Neuron-2-directed RNA Interaction …
Matched Products: … Evrysdi Powder for oral solution 0.75 mg/mL ... EVRYSDI POWDER FOR ORAL SOLUTION 0.75 MG/ML …

Mepivacaine

A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Approved
Vet approved
Matched Synonyms: … 1-methyl-2',6'-pipecoloxylidide ... (+-)-1-Methyl-2',6'-pipecoloxylidide ... N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide …
Matched Iupac: … N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide …
Matched Description: … It is indicated for infiltration, nerve block, and epidural anesthesia. ... A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine ... Mepivacaine is effective topically only in large doses and therefore should not be used by this route …
Matched Mixtures name: … MEPISEAL-E ... Scandonest 2% L ... ODONTOCAINA ® 2% …
Matched Products: … A. T. O. MEPIVACAINE 3% PLAIN. SOLUCION INYECTYABLE ... MEPIVACAINA BONISCONTRO E GAZZONE ... Carbocaine 2% …

Influenza B virus B/Wisconsin/1/2010 live (attenuated) antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …

Triclabendazole

Triclabendazole, manufactured by Novartis pharmaceuticals, is an antihelminthic drug that was approved by the FDA in February 2019 for the treatment of fascioliasis in humans.[FDA label, L5452] Fascioliasis is a parasitic infection often caused by the helminth, Fasciola hepatica, which is also known as “the common liver fluke” or “the...
Approved
Investigational
Matched Iupac: … 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylsulfanyl)-1H-1,3-benzodiazole …
Matched Description: … February 2019 for the treatment of fascioliasis in humans. ... for human use. ... [FDA label, L5452] Fascioliasis is a parasitic infection often caused by the helminth, _Fasciola hepatica …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Baclofen

Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … 4-Amino-3-(4-chlorophenyl)butyric acid ... DL-4-Amino-3-p-chlorophenylbutanoic acid …
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence ... Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. …
Matched Products: … Baclofen Sintetica 2 mg/ml Intrathekal Infusionslösung …

Pembrolizumab

Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes...
Approved
Matched Description: … [A7624] In the time since its initial approval, pembrolizumab has been granted approval in the treatment ... [F136] It was developed by Merck & Co and first approved for the treatment of metastatic malignant melanoma ... onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. …
Matched Products: … Keytruda 100mg Solution for Infusion ... KEYTRUDA SOLUTION FOR INFUSION 25MG/ML …

Albuterol

Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a...
Approved
Vet approved
Matched Iupac: … 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol …
Matched Description: … Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in ... Salbutamol is formulated as a racemic mixture of the R- and S-isomers. ... pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. …
Matched Mixtures name: … ULAX-C ... SALBUTAMOLO E IPRATROPIO BROMURO EG ... COMBIVENT UNIT DOSE VIAL FOR INHALATION …
Matched Categories: … Drugs for Obstructive Airway Diseases ... Medications that reduce magnesium levels ... Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists …
Matched Products: … Injection 0.5mg Salbutamol In 1 Ml (500mcg/ml) ... VENTOLIN SOLUTION FOR IV INFUSION 1MG/ML ... Bolus Injection 0.25mg Salbutamol In 5ml (50mcg/ml) …

Coral snake (micrurus fulvius) immune globulin antivenin (equine)

North American Coral Snake Antivenin (Equine) is a horse-derived antivenin indicated for the treatment of envenomation caused by North American coral snake bites. It is intravenously administered so that the antivenin binds to and neutralizes coral snake venom. The antivenin is a refined, concentrated, and lyophilized preparation of serum globulins...
Approved
Experimental
Matched Description: … North American Coral Snake Antivenin (Equine) is a horse-derived antivenin indicated for the treatment ... The antivenin is a refined, concentrated, and lyophilized preparation of serum globulins obtained by …

Edetate calcium disodium anhydrous

Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Iupac: … calcium disodium 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate …
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Oxidronic acid

Approved
Matched Products: … TECHNESCAN HDP FOR INJECTION 3 mg/vial ... TECHNESCAN HDP POWDER FOR INJECTION 3.15 mg/vial …

Abametapir

Abametapir is a novel pediculicidal metalloproteinase inhibitor used to treat infestations of head lice. The life cycle of head lice (Pediculus capitis) is approximately 30 days, seven to twelve of which are spent as eggs laid on hair shafts near the scalp. Topical pediculicides generally lack adequate ovicidal activity, including...
Approved
Investigational
Matched Description: … [A216178] Abametapir was first approved for use in the United States under the brand name Xeglyze ... The improved ovicidal activity (90-100% _in vitro_) of abemetapir allows for a single administration, ... agents like permethrin and [pyrethrins]/[piperonyl butoxide] may be significant in some areas. …

Basiliximab

A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell...
Approved
Investigational
Matched Description: … agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known ... A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive ... It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically …
Matched Categories: … Interleukin-2 Receptor Antagonist ... Interleukin-2 Receptor Blocking Antibody ... Interleukin 2 Receptor-directed Antibody Interactions …
Matched Products: … SIMULECT FOR INJECTION 20 mg/vial ... SIMULECT LYOPHILISATE FOR INJECTION 20MG PER VIAL …

Mitomycin

Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of Streptomyces caespitosus.[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. Few other antibiotics have been...
Approved
Matched Synonyms: … Mitocin-C ... Mitomycin C ... Mitomycin-C …
Matched Description: … [A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety ... of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper Tract ... Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Heterocyclic Compounds, 2-Ring …
Matched Products: … MITOMYCIN-C KYOWA FOR INJECTION 2 mg/vial ... MITOMYCIN-C KYOWA FOR INJECTION 10 mg/vial ... Mitomycin C "Kyowa" 2 mg - Trockenstechampullen …

Anidulafungin

Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366. There is preliminary evidence that it has a similar safety profile to caspofungin.
Approved
Investigational
Matched Iupac: … N-[(3S,6S,9S,11R,15S,18S,20R,21R,24S,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,21,25 …
Matched Description: … There is preliminary evidence that it has a similar safety profile to caspofungin. ... anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in …
Matched Categories: … Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … GIXOFU 100 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... ANIDACCORD 100 POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100 MG ... ERAXIS 100MG FOR INJECTION …

Bicisate

Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester. It is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl...
Approved
Investigational
Matched Iupac: … ethyl (2R)-2-[(2-{[(2R)-1-ethoxy-1-oxo-3-sulfanylpropan-2-yl]amino}ethyl)amino]-3-sulfanylpropanoate …
Matched Description: … It is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon ... Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ... [A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved …
Matched Salts cas: … 14344-58-2 …
Matched Products: … NEUROLITE KIT FOR THE PREPARATION OF Tc99m BICISATE FOR INJECTION ... MON.ECD KIT 1 MG IV ENJEKSİYON İÇİN LİYOZFİLİZE TOZ İÇEREN FLAKON, 2 ADET …

Isopropyl alcohol

An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Approved
Investigational
Matched Synonyms: … 2-Propanol …
Matched Iupac: … propan-2-ol …
Matched Description: … It is used in the manufacture of acetone and its derivatives and as a solvent. ... It is a colorless liquid having disinfectant properties. …
Matched Mixtures name: … C-tizers 99.9 ... Sooth-a-Sting ... 3เอ็ม ซีเอชจี แพด …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Alpet E-3 ... Zep Alpet E-3 Sanitizer ... Coghlans Survival In A Can …

Rasburicase

Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Approved
Investigational
Matched Description: … The cDNA coding for rasburicase was cloned from a strain of _Aspergillus flavus_. ... Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces …
Matched Categories: … Detoxifying Agents for Antineoplastic Treatment …
Matched Products: … FASTURTEC POWDER FOR SOLUTION FOR INFUSION 1.5 mg/vial …

Gadoxetic acid

Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. Gadoxetate is a...
Approved
Matched Iupac: … gadolinium(3+) ion 2-[(2-{[(2S)-2-[bis(carboxymethyl)amino]-3-(4-ethoxyphenyl)propyl](carboxylatomethyl …
Matched Description: … Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which ... its salt form, gadoxetate disodium, is used for intravenous injection. ... disodium, is marketed by Bayer HealthCare Pharmaceuticals under the brand name EOVIST and FDA approved in …
Matched Salts cas: … 135326-22-6 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Primovist 0.25 mmol/ml Solution for injection ... PRIMOVIST 0.25 MMOL/ML, SOLUTION FOR INJECTION …

Pyrethrum extract

Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Description: … Pyrethrin refers to a more refined extract of pyrethrum. ... Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species. …
Matched Mixtures name: … Mata Piojos A Pediculicide Low Foaming ... R & C Shampoo With Conditioner ... CVS 3 Step Lice Solution …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Nystatin

Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably Candida species. It is one of the most effective antifungal agents synthesized by bacteria, in this case a strain of Streptomyces noursei, and is closely related to amphotericin...
Approved
Vet approved
Matched Iupac: … 18S,19E,21E,25E,27E,29E,31E,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2- …
Matched Description: … for systemic use. ... [L10686] It is one of the most effective antifungal agents synthesized by bacteria, in this case a strain ... nystatin, however, is associated with significant toxicity and is not available in a formulation appropriate …
Matched Mixtures name: … OLEUM ZINC OX C NYSTAT SR ... OLEUM ZINCI OXID C NYST SR …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Antifungals for Topical Use ... Antifungals for Dermatological Use …
Matched Products: … BISTATIN-F …

Streptococcus pneumoniae type 2 capsular polysaccharide antigen

Streptococcus pneumoniae type 2 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 2 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Synonyms: … pneumococcal capsular polysaccharide type 2 vaccine …
Matched Name: … Streptococcus pneumoniae type 2 capsular polysaccharide antigen …
Matched Description: … Streptococcus pneumoniae type 2 capsular polysaccharide antigen is a vaccine that contains highly purified ... It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease ... capsular polysaccharides from the invasive pneumococcal type 2 of *Streptococcus pneumoniae*. …
Matched Mixtures name: … PNEUMOVAX 23 Injektionslösung in einer Fertigspritze ... PNEUMOVAX 23 Injektionslösung in einer Durchstechflasche …

Streptococcus pneumoniae type 20 capsular polysaccharide antigen

Streptococcus pneumoniae type 20 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 20 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 20 capsular polysaccharide antigen is a vaccine that contains highly purified ... It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease …
Matched Mixtures name: … PNEUMOVAX 23 Injektionslösung in einer Fertigspritze ... PNEUMOVAX 23 Injektionslösung in einer Durchstechflasche …

Black widow spider antivenin (equine)

Black widow spider (Latrodectus mactans) antivenin is a treatment for black widow spider bites derived from the serum of healthy horses immunized against black widow spider venom.
Approved
Matched Synonyms: … LATRODECTUS IMMUNE F(AB)2 …
Matched Description: … Black widow spider (_Latrodectus mactans_) antivenin is a treatment for black widow spider bites derived …

Phenol

Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Description: … Additionally, phenol and its related compounds are used in surgical ingrown toenail treatment, a process ... Phenol is also used as an oral analgesic or anesthetic in products such as Chloraseptic to treat pharyngitis ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly …
Matched Mixtures name: … Kank-A with Blistex Medicated Lip ... DİŞİNOL 2 G + 0,5 G + 3,5 G/10 ML ÇÖZELTİ ... Sterile Diluent for Allergenic Extract …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Sclerosing Agents for Local Injection …
Matched Products: … Pain A Lay ... Sterile Diluent for Allergenic Extract …

Hydrocortisone phosphate

Approved
Vet approved
Matched Iupac: … ,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}phosphonic acid ... {2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Displaying drugs 576 - 600 of 15295 in total