Displaying drugs 326 - 350 of 12359 in total
Glucarpidase
Glucarpidase is a recombinant carboxypeptidase G2 produced by genetically modified Escherichia coli bacteria. It is a 390-amino acid homodimer protein. High-dose methotrexate, an antifolate agent, has been widely and safely used for many decades in treating various cancers; however, even with aggressive hydration, urine alkalinization, and leucovorin rescue, some patients...
Approved
Investigational
Matched Description: … It is a 390-amino acid homodimer protein. ... Glucarpidase is a recombinant carboxypeptidase G2 produced by genetically modified _Escherichia coli_ …
Esketamine
Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness preceding suicide.[L5596,A175462] On March 5, 2019, the nasal spray drug, esketamine, also known as Spravato (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression.
Esketamine is the s-enantiomer of Ketamine. Ketamine...
Approved
Investigational
Matched Synonyms: … (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone …
Matched Iupac: … (2S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one …
Matched Description: … Ketamine is a mixture of two enantiomers (mirror image molecules). ... Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness ... The intranasal route of administration for this drug allows for easy administration and a fast onset …
Matched Iupac: … (2S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one …
Matched Description: … Ketamine is a mixture of two enantiomers (mirror image molecules). ... Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness ... The intranasal route of administration for this drug allows for easy administration and a fast onset …
Dimethyl fumarate
Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.[A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor...
Approved
Investigational
Matched Synonyms: … (E)-But-2-enedioic acid dimethyl ester …
Matched Iupac: … 1,4-dimethyl (2E)-but-2-enedioate …
Matched Description: … -like 2 (Nrf2) pathway that is activated in response to oxidative stress. ... active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2) …
Matched Iupac: … 1,4-dimethyl (2E)-but-2-enedioate …
Matched Description: … -like 2 (Nrf2) pathway that is activated in response to oxidative stress. ... active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2) …
Calcium gluconate
Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle.
Calcium Gluconate Injection,...
Approved
Vet approved
Matched Synonyms: … D-gluconic acid, calcium salt (2:1) …
Matched Description: … Each 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate ... It can also be taken by mouth but is not recommended by injection into a muscle. ... Calcium Gluconate Injection, USP is a sterile, nonpyrogenic supersaturated solution of calcium gluconate …
Matched Mixtures name: … ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKI ... ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKI ... ELETTROLITICA REIDRATANTE CON GLUCOSIO E CALCIO GLUCONATO MONICO …
Matched Products: … 2% Calcium Gluconate In Sodium Chloride Injection …
Matched Description: … Each 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate ... It can also be taken by mouth but is not recommended by injection into a muscle. ... Calcium Gluconate Injection, USP is a sterile, nonpyrogenic supersaturated solution of calcium gluconate …
Matched Mixtures name: … ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKI ... ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKI ... ELETTROLITICA REIDRATANTE CON GLUCOSIO E CALCIO GLUCONATO MONICO …
Matched Products: … 2% Calcium Gluconate In Sodium Chloride Injection …
Elacestrant
Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist.[A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer.[L44918,L44948] It received a similar approval in the EU in September 2023. Elacestrant binds to estrogen receptor-alpha (ERα)...
Approved
Investigational
Matched Synonyms: … -2-ol ... (2R)-2-(2-(ethyl-((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxy-phenyl)tetralin-6-ol ... 2-naphthalenol, 6-(2-(ethyl((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxyphenyl)-5,6,7,8-tetrahydro …
Matched Iupac: … -2-ol ... (6R)-6-{2-[ethyl({4-[2-(ethylamino)ethyl]phenyl}methyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen …
Matched Description: … [L44918,L44948] It received a similar approval in the EU in September 2023. ... Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist. ... SERD represents a therapeutic approach for the treatment of endocrine-resistant breast cancers. …
Matched Iupac: … -2-ol ... (6R)-6-{2-[ethyl({4-[2-(ethylamino)ethyl]phenyl}methyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen …
Matched Description: … [L44918,L44948] It received a similar approval in the EU in September 2023. ... Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist. ... SERD represents a therapeutic approach for the treatment of endocrine-resistant breast cancers. …
Fenofibrate
Fenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591]
Fenofibrate was granted FDA approval on 31 December 1993.
Approved
Matched Synonyms: … Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate ... Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate ... 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester …
Matched Iupac: … propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate …
Matched Description: … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. …
Matched Products: … Taro-fenofibrate E ... Mint-fenofibrate E ... Sandoz Fenofibrate E …
Matched Iupac: … propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate …
Matched Description: … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. …
Matched Products: … Taro-fenofibrate E ... Mint-fenofibrate E ... Sandoz Fenofibrate E …
Synthetic camphor
Approved
Experimental
Matched Synonyms: … 2-bornanone ... 2-camphanone ... 1,7,7-trimethylbicyclo(2.2.1)heptan-2-one …
Matched Iupac: … 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Matched Mixtures name: … C-Patch ... My Omega 3 Rub ... Dental C-Patch …
Matched Iupac: … 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Matched Mixtures name: … C-Patch ... My Omega 3 Rub ... Dental C-Patch …
Follitropin
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched International brands: … Cinnal-F …
Matched Synonyms: … FSH-a …
Matched Description: … However, a more recent study showed there is may be a slight clinical difference, with the alpha form ... tending towards a higher pregnancy rate and the beta form tending towards a lower pregnancy rate, but ... Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which …
Matched Mixtures name: … GONAL F ... PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 3 ADET ... ICIN SC ENJEKSIYONLUK COZELTI TOZU ICEREN FLAKON VE KULLANIMA HAZIR ENJEKTORDE COZUCU (1 ADET FLAKON + 2 …
Matched Products: … Gonal-f 300 iu/0.5 ml (22 mcg/0.5 ml) Solution for Injection in a pre-filled pen ... GONAL-F 300IU/0.5 ML (22 MICROGRAMS/0.5 ML) ... Gonal-f 900 iu/1.5 ml (66 mcg/1.5 ml) Solution for Injection in a pre-filled pen …
Matched Synonyms: … FSH-a …
Matched Description: … However, a more recent study showed there is may be a slight clinical difference, with the alpha form ... tending towards a higher pregnancy rate and the beta form tending towards a lower pregnancy rate, but ... Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which …
Matched Mixtures name: … GONAL F ... PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 3 ADET ... ICIN SC ENJEKSIYONLUK COZELTI TOZU ICEREN FLAKON VE KULLANIMA HAZIR ENJEKTORDE COZUCU (1 ADET FLAKON + 2 …
Matched Products: … Gonal-f 300 iu/0.5 ml (22 mcg/0.5 ml) Solution for Injection in a pre-filled pen ... GONAL-F 300IU/0.5 ML (22 MICROGRAMS/0.5 ML) ... Gonal-f 900 iu/1.5 ml (66 mcg/1.5 ml) Solution for Injection in a pre-filled pen …
Artemether
Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including...
Approved
Rifabutin
A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
Approved
Investigational
Matched Synonyms: … 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIV ... 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin S …
Matched Iupac: … 12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2- …
Matched Description: … A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium …
Matched Iupac: … 12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2- …
Matched Description: … A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium …
1,2-Distearoyllecithin
Approved
Experimental
Matched Synonyms: … 1,2-Distearoyl-sn-glycero-3-phosphocholine …
Matched Iupac: … (2-{[2,3-bis(octadecanoyloxy)propyl phosphonato]oxy}ethyl)trimethylazanium …
Matched Iupac: … (2-{[2,3-bis(octadecanoyloxy)propyl phosphonato]oxy}ethyl)trimethylazanium …
Probucol
A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
Approved
Investigational
Matched Iupac: … 2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol …
Matched Description: … A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Formestane
Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formestane suppresses estrogen production from anabolic steroids or prohormones. Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity and mild aromatase inhibitor activity....
Approved
Investigational
Withdrawn
Matched Synonyms: … 4-OH-A …
Matched Iupac: … 9bS,11aS)-6-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … It is listed as a prohibited substance by the World Anti-Doping Agency for use in athletes. ... Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity …
Matched Iupac: … 9bS,11aS)-6-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … It is listed as a prohibited substance by the World Anti-Doping Agency for use in athletes. ... Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity …
Coagulation Factor IX Human
Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Approved
Matched Mixtures name: … PROTROMPLEX TIM 3 ... PROTROMPLEX TIM 3 …
Matched Products: … OCTANINE F ... OCTANINE F LYOPHILLISED POWDER FOR INTRAVENOUS ADMINISTRATION ... Octanine F 50 I.E./ml Pulver und Lösungsmittel zur Herstellung einer Injektionslösung …
Matched Products: … OCTANINE F ... OCTANINE F LYOPHILLISED POWDER FOR INTRAVENOUS ADMINISTRATION ... Octanine F 50 I.E./ml Pulver und Lösungsmittel zur Herstellung einer Injektionslösung …
Baclofen
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … 4-Amino-3-(4-chlorophenyl)butyric acid ... DL-4-Amino-3-p-chlorophenylbutanoic acid …
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Description: … Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. ... [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the …
Matched Products: … Baclofen Sintetica 2 mg/ml Intrathekal Infusionslösung …
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Description: … Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. ... [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the …
Matched Products: … Baclofen Sintetica 2 mg/ml Intrathekal Infusionslösung …
Heterotheca inuloides flower
Heterotheca inuloides flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Heterotheca inuloides flower is a plant/plant extract used in some OTC (over-the-counter) products. …
Edetate calcium disodium anhydrous
Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Iupac: … calcium disodium 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate …
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Efanesoctocog alfa
Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding episodes in patients with hemophilia A. The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality...
Approved
Investigational
Matched Description: … VIII therapy for hemophilia A. ... Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the ... [L45379] The use of FVIII replacement products is beneficial in patients with hemophilia A; however, …
Ambrosia acanthicarpa pollen
Ambrosia acanthicarpa pollen is the pollen of the Ambrosia acanthicarpa plant. Ambrosia acanthicarpa pollen is mainly used in allergenic testing.
Approved
Ofatumumab
Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Description: … Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. ... It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic ... [L12612] Although it has a similar molecular mechanism of action as [rituximab], another CD-20 monoclonal …
Matched Products: … İNFÜZYONLUK ÇÖZELTİ KONSATRESİ İÇEREN FLAKON (3 ADET) …
Matched Products: … İNFÜZYONLUK ÇÖZELTİ KONSATRESİ İÇEREN FLAKON (3 ADET) …
Coagulation factor X human
Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe...
Approved
Investigational
Matched Description: … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... It is a two-chain glycoprotein with the molecular weight of approximately 59 kDa [A31472]. ... Coagulation Factor X is a vitamin K-dependent, liver-produced serine protease that serves as the first …
Matched Mixtures name: … PROTROMPLEX TIM 3 ... PROTROMPLEX TIM 3 …
Matched Mixtures name: … PROTROMPLEX TIM 3 ... PROTROMPLEX TIM 3 …
Clove oil
Clove oil is obtained by extraction from the dried flower buds of the clove plant. Traditionally, it has been used as a flavouring spice in foods, or as a fragrance. It is also found in topical analgesics. Clove oil has shown to exert some antimicrobial activities. The antioxidant and antimicrobial...
Approved
Nutraceutical
Matched Description: … Traditionally, it has been used as a flavouring spice in foods, or as a fragrance. ... The FDA categorizes clove oil as generally recognized as safe (GRAS) for use in dental cement or as a …
Matched Mixtures name: … DİŞİNOL 2 G + 0,5 G + 3,5 G/10 ML ÇÖZELTİ …
Matched Mixtures name: … DİŞİNOL 2 G + 0,5 G + 3,5 G/10 ML ÇÖZELTİ …
Fluorouracil
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Approved
Matched Description: … A pyrimidine analog that is an antineoplastic antimetabolite. …
Matched Categories: … Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Matched Categories: … Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Displaying drugs 326 - 350 of 12359 in total