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Displaying drugs 26 - 50 of 916 in total

Vilazodone

Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Salts name: … Vilazodone hydrochloride …
Matched Products: … Vilazodone Hydrochloride ... Vilazodone hydrochloride …

Desipramine

Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Description: … Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). …
Matched Salts name: … Desipramine hydrochloride …
Matched Products: … Desipramine Hydrochloride …

Phenazopyridine

Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. It is...
Approved
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Phenazopyridine hydrochloride …
Matched Products: … Phenazopyridine Hydrochloride ... Phenazopyridine hydrochloride ... Phenazopyridine Hydrochloride 97.5mg …

Isoprenaline

Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Salts name: … Isoprenaline hydrochloride …
Matched Products: … Isoproterenol Hydrochloride ... Isoproterenol hydrochloride ... Isoproterenol Hydrochloride Injection USP …

Imipramine

Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Salts name: … Imipramine hydrochloride …
Matched Products: … Imipramine Hydrochloride ... Imipramine hydrochloride ... Imipramine Hydrochloride Tablets 25mg …

Midodrine

An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Approved
Matched Salts name: … Midodrine hydrochloride …
Matched Products: … Midodrine Hydrochloride ... Midodrine hydrochloride …

Memantine

Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Mixtures name: … Memantine Hydrochloride ... Memantine Hydrochloride ... Memantine Hydrochloride …
Matched Salts name: … Memantine hydrochloride …
Matched Products: … Memantine Hydrochloride ... Memantine hydrochloride ... Mematine Hydrochloride …

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Mixtures name: … Promethazine Hydrochloride and Phenylephrine Hydrochloride ... Promethazine Hydrochloride and Phenylephrine Hydrochloride ... Promethazine Hydrochloride and Phenylephrine Hydrochloride …
Matched Salts name: … Phenylephrine hydrochloride …
Matched Products: … Phenylephrine Hydrochloride Phenylephrine Hydrochloride ... Phenylephrine hydrochloride ... Phenylephrine Hydrochloride …

Procainamide

A derivative of procaine with less CNS action.
Approved
Matched Salts name: … Procainamide hydrochloride …
Matched Products: … Procainamide Hydrochloride ... Procainamide Hydrochloride Injection USP …

Alfuzosin

Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases...
Approved
Investigational
Matched Salts name: … Alfuzosin hydrochloride …
Matched Products: … Alfuzosin Hydrochloride ... Alfuzosin hydrochloride ... Alfuzosin Hydrochloride ER …

Hydroxyzine

Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride …

Ropivacaine

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Approved
Matched Salts name: … Ropivacaine hydrochloride ... Ropivacaine hydrochloride anhydrous …
Matched Products: … Ropivacaine Hydrochloride ... Ropivacaine hydrochloride ... Ropivacaine Hydrochloride Injection …

Raloxifene

Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Salts name: … Raloxifene Hydrochloride …
Matched Products: … Raloxifene Hydrochloride ... Raloxifene hydrochloride …

Methadone

Methadone is a potent synthetic analgesic that works as a full ยต-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Salts name: … Methadone hydrochloride …
Matched Products: … Methadone Hydrochloride ... Methadone hydrochloride ... Methadone Hydrochloride Oral Concentrate USP …

Papaverine

An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Salts name: … Papaverine hydrochloride …
Matched Products: … Papaverine Hydrochloride ... PAPAVERINE HYDROCHLORIDE ... Papaverine Hydrochloride Injection USP …

Sotalol

Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening...
Approved
Matched Salts name: … Sotalol hydrochloride …
Matched Products: … Sotalol Hydrochloride ... Sotalol hydrochloride ... Sotalol Hydrochloride AF …

Esmolol

Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Description: … FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride …
Matched Salts name: … Esmolol hydrochloride …
Matched Products: … Esmolol Hydrochloride ... Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride …

Guanidine

A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is...
Approved
Matched Salts name: … Guanidine hydrochloride …
Matched Products: … Guanidine hydrochloride …

Tolazoline

A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Approved
Vet approved
Matched Salts name: … Tolazoline hydrochloride …
Matched Products: … Priscoline hydrochloride …

Tiagabine

Tiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants. Though the exact mechanism by which tiagabine exerts its effect on the human body is unknown, it does appear to operate as a selective GABA reuptake inhibitor.
Approved
Investigational
Matched Salts name: … Tiagabine hydrochloride …
Matched Products: … Tiagabine Hydrochloride …

Benzphetamine

A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Approved
Illicit
Matched Salts name: … Benzphetamine hydrochloride …
Matched Products: … Benzphetamine Hydrochloride …

Cyproheptadine

Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in the treatment of serotonin syndrome.
Approved
Matched Salts name: … Cyproheptadine hydrochloride …
Matched Products: … Cyproheptadine Hydrochloride ... CYPROHEPTADINE HYDROCHLORIDE ... CYPROHEPTADINE HYDROCHLORIDE SYRUP …

Chlormerodrin

Chlormerodrin is a mercurial compound with toxic side effects that was previously used as a diuretic. The radiolabeled form has been used as a diagnostic and research tool. It is no longer used and has been replaced with new classes of diuretic drugs.
Approved
Withdrawn

Pyridoxine

Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Mixtures name: … Doxylamine succinate and pyridoxine hydrochloride ... Doxylamine succinate and pyridoxine hydrochloride ... Doxylamine Succinate and Pyridoxine Hydrochloride …
Matched Salts name: … Pyridoxine hydrochloride …
Matched Products: … Pyridoxine Hydrochloride ... Pyridoxine Hydrochloride Injection, USP ... Pyridoxine Hydrochloride Injection 100mg/ml …

Ethambutol

Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Salts name: … Ethambutol hydrochloride …
Matched Products: … Ethambutol Hydrochloride ... ETHAMBUTOL HYDROCHLORIDE …
Displaying drugs 26 - 50 of 916 in total