Identification
NamePyridoxine
Accession NumberDB00165  (NUTR00002, APRD00204)
TypeSmall Molecule
GroupsApproved, Nutraceutical, Vet Approved
Description

Pyridoxine is the 4-methanol form of vitamin B6 and is converted to pyridoxal 5-phosphate in the body. Pyridoxal 5-phosphate is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and vitamin B6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading. [PubChem]

Structure
Thumb
Synonyms
2-Methyl-3-hydroxy-4,5-dihydroxymethylpyridine
3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine
3-Hydroxy-4,5-dimethylol-alpha-picoline
5-Hydroxy-6-methyl-3,4-pyridinedimethanol
Pyridoxine
Pyridoxol
Vitamin B6
External IDs Not Available
Product Ingredients
IngredientUNIICASInChI KeyDetails
Pyridoxine hydrochloride68Y4CF58BV 58-56-0ZUFQODAHGAHPFQ-UHFFFAOYSA-NDetails
Product Images
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Cataplex F Tab 2mgTablet2 mgOralStandard Process Inc.Not applicableNot applicableCanada
Pyridoxine HCl Inj 100mg/mlLiquid100 mgIntramuscular; IntravenousKripps Pharmacy Ltd.1979-12-31Not applicableCanada
Pyridoxine Hydrochloride Injection 100mg/mlSolution100 mgIntramuscular; IntravenousHospira, Inc.1981-12-31Not applicableCanada
Pyridoxine Hydrochloride Injection USP 100 mg/mlSolution100 mgIntramuscular; IntravenousAlveda Pharmaceuticals IncNot applicableNot applicableCanada
Pyridoxine Hydrochloride Injection, USPSolution100 mgIntramuscular; IntravenousMylan Pharmaceuticals2002-06-01Not applicableCanada
Vitamin B6 250 Mg CapsulesCapsule250 mgOralSelf Health Resource CentreNot applicableNot applicableCanada
Vitamin B6 TabletTablet100 mgOralLeiner Health ProductsNot applicableNot applicableCanada
Approved Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Pyridoxine HydrochlorideInjection, solution100 mg/mLIntramuscular; IntravenousFresenius Kabi1972-08-14Not applicableUs
Pyridoxine HydrochlorideInjection, solution100 mg/mLIntramuscular; IntravenousMylan Institutional2016-09-01Not applicableUs
Approved Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
B-6 500mg Continuous ReleasedTablet, extended release500 mgOralGahler Enterprises Ltd.1981-12-312007-08-07Canada
B-6 Caps 250mgCapsule250 mgOralTwin Laboratories Inc.1995-12-311999-11-10Canada
B6 100mg Pyridoxine HClTablet100 mgOralWn Pharmaceuticals Ltd.2001-10-012009-09-28Canada
B6 25 Tab 25mgTablet25 mgOralLe Naturiste J.M.B. Inc.1990-12-311997-07-23Canada
B6 250 Caplet 250mgTablet250 mgOralHealth Wise Nutrition Inc.1996-11-131997-08-07Canada
B6 400mg Ctr TabTablet, extended release400 mgOralBioenergy Inc.1979-12-311998-06-03Canada
B6 Cap 100mgCapsule100 mgOralGahler Enterprises Ltd.1989-12-312008-07-17Canada
B6 Pyridoxine HCl Tab 50mgTablet50 mgOralGahler Enterprises Ltd.1984-12-312008-07-17Canada
B6 Tab 100mgTablet100 mgOralAlbi Naturals1979-12-312008-07-17Canada
B6 Tablets 100mgTablet100 mgOralGahler Enterprises Ltd.1988-12-312008-07-17Canada
Formula A.L.- Tab 17mgTablet17 mgOralAbundance Marketing Ltd.1996-11-051999-08-06Canada
Formule No 202 Profil Tab 8.45gmTablet8.45 mgOralPharmalab Inc.1987-12-312001-07-30Canada
Hi Potency Klb6 Tab 17mgTablet17 mgOralSwiss Herbal Remedies Ltd.1981-12-312003-09-10Canada
Klb 6 TabTablet6 mgOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Klb 6 Tab 8.33mgTablet8.33 mgOralPure Life International Prods Inc.1992-12-312001-08-07Canada
Klb6 Tablets 17mgTablet17 mgOralGahler Enterprises Ltd.1988-12-312002-07-17Canada
Lgb-dtx Tab 10mgTablet10 mgOralMetagenics, Inc.1989-12-312002-10-07Canada
Nutrol-B6 Tab 100mgTablet100 mgOralRolmex International Inc.1989-12-311997-08-08Canada
Pyridoxen Tab 50mgTablet50 mgOralSantÉ Naturelle (Ag) LtÉe1987-12-311999-08-18Canada
PyridoxineTablet250 mgOralSeroyal International Inc.1988-12-312009-07-06Canada
Pyridoxine HCl Tab 100mgTablet100 mgOralEverest Pharmaceuticals Ltd.1980-12-311999-07-14Canada
Pyridoxine HCl Tab 25mgTablet25 mgOralSwiss Herbal Remedies Ltd.1971-12-312003-09-10Canada
Pyridoxine HCl Tab 25mgTablet25 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1957-12-312002-07-31Canada
Pyridoxine HCl Tab 50mgTablet50 mgOralSwiss Herbal Remedies Ltd.1989-12-312004-09-03Canada
Pyridoxine-S Tab 50mgTablet50 mgOralNutri West Products Ltd.1993-12-311997-08-05Canada
Super Klb6 Tab 17mgTablet17 mgOralCountry Health Laboratories Ltd.1981-12-312001-07-27Canada
Super Klb6 Tab 17mgTablet17 mgOralAlbi Imports Ltd.1981-12-311996-09-09Canada
Vit B6 Ctr Srt 100mgTablet, extended release100 mgOralBioenergy Inc.1981-12-311998-06-03Canada
Vit B6 Pyridoxine HCl Tab 50mg USPTablet50 mgOralPure Life International Prods Inc.1992-12-312001-08-07Canada
Vit B6 Tab 250mgTablet250 mgOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Vita-doxine Cap 250mgCapsule250 mgOralLes Laboratoires Vachon Inc.1990-12-312001-08-07Canada
Vitamin B-6 50 Mg TabletTablet50 mgOralGeneral Nutrition Canada Inc.1997-04-182005-08-05Canada
Vitamin B-6 100mgCapsule100 mgOralNutraceutical Corporation2003-10-012007-08-02Canada
Vitamin B-6 100mg TabTablet100 mgOralPharmavite1993-12-312006-07-05Canada
Vitamin B-6 17mg TabTablet17 mgOralPharmavite1993-12-311998-09-08Canada
Vitamin B-6 200mgCapsule200 mgOralNutraceutical Corporation2003-09-022006-08-02Canada
Vitamin B-6 Tab 200mgTablet200 mgOralNutri West Products Ltd.1988-12-312002-06-14Canada
Vitamin B6Tablet250 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1983-12-312002-07-31Canada
Vitamin B6 50mg TabTablet50 mgOralNutricorp International1993-12-312009-08-05Canada
Vitamin B6 100 mgCapsule100 mgOralHolista Health (Canada) Inc.2002-11-132008-07-17Canada
Vitamin B6 100 Mg USPTablet100 mgOralAccurex Health Care Manufacturing Inc.2002-06-262009-07-31Canada
Vitamin B6 100mgTablet100 mgOralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
Vitamin B6 100mg CapletTablet100 mgOralHealth Wise Nutrition Inc.1994-12-312002-07-18Canada
Vitamin B6 100mg TabTablet100 mgOralJamieson Laboratories Ltd1994-12-311996-09-10Canada
Vitamin B6 200mgTablet200 mgOralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
Vitamin B6 50mgTablet50 mgOralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
Vitamin B6 Cap 250mgCapsule250 mgOralQuest Vitamins A Div Of Purity Life Health Products1980-12-312002-07-29Canada
Vitamin B6 Capsules 100mgCapsule100 mgOralQuest Vitamins A Div Of Purity Life Health Products1989-12-312001-07-06Canada
Vitamin B6 Capsules 3.5mgCapsule3.5 mgOralVita Health Products Inc1990-12-311997-08-18Canada
Vitamin B6 Tab 100mgTablet100 mgOralWampole Brands1979-12-312004-06-29Canada
Vitamin B6 Tab 100mgTablet100 mgOralNutristar Health Products (1987) Inc.1983-12-311996-09-09Canada
Vitamin B6 Tab 100mgTablet100 mgOralCountry Health Laboratories Ltd.1982-12-312001-07-27Canada
Vitamin B6 Tab 100mgTablet100 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1980-12-312002-07-31Canada
Vitamin B6 Tab 100mgTablet100 mgOralShoppers Drug Mart Inc.1980-12-311997-08-15Canada
Vitamin B6 Tab 100mg USPTablet100 mgOralAlive Vitamins1987-12-311997-08-11Canada
Vitamin B6 Tab 250mgTablet250 mgOralVita Health Products Inc1985-12-312005-07-20Canada
Vitamin B6 Tab 250mgTablet250 mgOralNutri Dyn Products Ltd.1976-12-311997-08-22Canada
Vitamin B6 Tab 25mgTablet25 mgOralAlbi Naturals1979-12-312008-07-17Canada
Vitamin B6 Tab 25mgTablet25 mgOralAvacare, Division Of Jeunique International Inc.1985-12-311996-09-09Canada
Vitamin B6 Tab 25mgTablet25 mgOralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1978-12-312002-07-29Canada
Vitamin B6 Tab 25mgTablet25 mgOralVita Health Products Inc1975-12-312002-07-31Canada
Vitamin B6 Tab 50mgTablet50 mgOralVita Health Products Inc1977-12-312008-08-05Canada
Vitamin B6 Tab 50mgTablet50 mgOralNutristar Health Products (1987) Inc.1980-12-311996-09-09Canada
Vitamin B6 Tab 50mgTablet50 mgOralQuest Vitamins A Div Of Purity Life Health Products1977-12-312001-07-06Canada
Vitamin B6 Tablets 250mgTablet250 mgOralNu Life Nutrition Ltd.1987-12-312005-03-15Canada
Vitamin B6 Tablets-250mgTablet250 mgOralDa Vinci Laboratories, Division Of Foodscience Corporation2002-06-172007-07-18Canada
Vitamine B6 100 Mg - TabletTablet100 mgOralNobel Pharm Enr.1995-12-312001-10-15Canada
Vitamine B6 100mgTablet100 mgOralGamme Nature1990-12-312004-07-26Canada
Vitamine B6 25mg ComprimeTablet25 mgOralBio Vita1988-03-231997-08-07Canada
Vitamine B6 Tab 100mg USPTablet100 mgOralLaboratoire Lalco Inc.1986-12-312004-07-26Canada
Vitamine B6 Tab 250mgTablet250 mgOralLes Produits Gerbex Inc.1985-12-311997-08-11Canada
Vitamine B6 Tab 25mg USP ChewableTablet25 mgOralLab Gernetic Int Ltee1985-12-311997-02-21Canada
Unapproved/Other Products Not Available
International Brands
NameCompany
BecilanNot Available
BeesixNot Available
BenadonNot Available
BonasanitNot Available
Hexa-BetalinNot Available
HexobionNot Available
NestrexNot Available
Brand mixtures
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
A.R.T.H. Away FormulaCapsuleOralAbundance Marketing Ltd.1999-02-012006-06-16Canada
Acetabolan III Vitamin and Mineral SupplementCapsuleOralIovate Health Sciences International Inc.2003-12-052007-07-18Canada
Acetabolan-II Vitamin and Mineral SupplementCapsuleOralIovate Health Sciences International Inc.2000-11-202005-06-21Canada
Active FeTabletOralGm Pharmaceuticals2013-11-11Not applicableUs
AcvTabletOralAbundance Marketing Ltd.2001-10-012004-06-30Canada
Adrenogist TabTabletOralPure Life International Prods Inc.1992-12-312000-07-27Canada
Adult Infuvite Multiple VitaminsInjection, solutionIntravenousSandoz2005-05-18Not applicableUs
Advanced 2000 CapsulesCapsuleOralBody Gold, A Division Of Pep Products, Inc.2000-01-012002-08-22Canada
AlertonicElixirOralOdan Laboratories Ltd1995-12-31Not applicableCanada
Allbee With C 550 CapCapsuleOralWhitehall Robins Inc.1994-12-312003-08-01Canada
Allbee With Vitamin C CapCapsuleOralWhitehall Robins Inc.1994-12-312000-07-26Canada
Alsimine W Vitamins A DCapsule; LiquidOralAlsi Cie Ltee1978-12-312003-05-21Canada
Am CapsCapsuleOralNew Vision Nutritionals Company1998-10-012002-11-20Canada
American Eagle Energizer Plus Vitamin Supplement DrinkLiquidOralP.S.W.C. Co., Inc.Not applicableNot applicableCanada
American Plus Energy & Vitamin DrinkLiquidOralP.S.W.C. Co., Inc.Not applicableNot applicableCanada
Animi-3CapsuleOralPbm Pharmaceuticals Inc.2011-06-01Not applicableUs
Animi-3 With Vitamin DCapsuleOralPbm Pharmaceuticals Inc.2011-06-01Not applicableUs
AntlervironCapsuleOralClassical Remedia LtdNot applicableNot applicableCanada
Apo-doxylamine/b6Tablet, delayed releaseOralApotex CorporationNot applicableNot applicableCanada
Aqua-S SupplementTabletOralGarden State NutritionalsNot applicableNot applicableCanada
Av-vite FbTabletOralAv Kare, Inc.2015-11-052016-01-20Us
B 50 CapsulesCapsuleOralRheingold Food International Ltd.1987-12-312007-07-26Canada
B 6 PlusTabletOralAnabolic Laboratories Inc.1967-12-312004-03-15Canada
B C Antistress CapCapsuleOralLes Laboratoires Bio SantÉ Inc.1992-12-311996-09-10Canada
B Complex 25mg Vitamin SupplementTabletOralGarden State Nutritionals1998-08-312000-06-07Canada
B Complex 50 Vitamin CapCapsuleOralBioforce Canada Inc.1994-12-311997-07-22Canada
B Complex 50+ CapletTabletOralHealth Wise Nutrition Inc.1994-12-312002-07-18Canada
B Complex 500 TabTabletOralNobel Pharm Enr.1981-12-311998-08-14Canada
B Complex Plus C 300mg TabTabletOralNutricorp International2000-08-012009-08-05Canada
B Complex TabletsTabletOralGolden Neo Life Diamite International, Limited1979-12-312000-08-06Canada
B Complex W C and B12 InjLiquidIntramuscular; IntravenousE L Stickley And Co Ltd.1963-12-311996-09-09Canada
B Complex W C Forte CapCapsuleOralEverest Pharmaceuticals Ltd.1980-12-311999-07-14Canada
B Complex W Vit C W Non-med Yeast&liver TabTabletOralPharmavite1991-12-311997-09-04Canada
B Complex W Vitamin C Fortis CapCapsuleOralShoppers Drug Mart Inc.1984-12-311998-08-14Canada
B Complex With C 300mgCapsuleOralVita Health Products Inc1985-12-312008-08-05Canada
B Complex With C 300mg TabTabletOralPharmavite1987-12-312005-07-15Canada
B Complex With C 550mgCapsuleOralVita Health Products Inc1990-12-312002-07-31Canada
B Compound 50mg TabTabletOralGahler Enterprises Ltd.1987-12-312009-09-28Canada
B Plus C 300mg Timed ReleaseTablet, extended releaseOralVita Health Products Inc1981-12-312008-08-05Canada
B Stress C + Iron & ViteTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1990-12-312004-07-26Canada
B Totum 500TabletOralDesbergers LtÉe, Division Of Technilab Inc.1966-12-311999-09-17Canada
B VirolElixirOralRolmex International Inc.1975-12-312008-07-09Canada
B With C 500 CapCapsuleOralPharmetics (2011) Inc.1995-12-312006-07-27Canada
B-100 CapsCapsuleOralNow Foods2005-05-192008-07-11Canada
B-100 Complex TabletsTablet, extended releaseOralViva Pharmaceutical Inc.2001-06-052009-12-18Canada
B-100 Hi Potency B Vitamins TabTabletOralNatrol, Inc.1994-12-312009-05-07Canada
B-100 Vitamin SupplementTablet, extended releaseOralGarden State Nutritionals1998-09-222000-06-07Canada
B-50 ComplexTabletOralVita Health Products Inc1977-12-312004-07-26Canada
B-50 Complex TabTabletOralVita Health Products Inc1988-12-311998-07-22Canada
B-50 Hi Potency B Vitamins TabTabletOralNatrol, Inc.1994-12-312006-09-26Canada
B-comboInjectionIntramuscularPerdido Key Health And Wellness Inc2015-11-23Not applicableUs
B-complexTabletOralEnrich International1999-11-112001-09-28Canada
B-complex 100TabletOralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
B-complex 50TabletOralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
B-complex TabTabletOralNatures Sunshine Products, Inc.1995-12-312009-08-07Canada
B-complex TabletsTabletOralShaklee Corporation1983-12-312000-01-24Canada
B-complex With Vitamin C, Biotin, Folic AcidTabletOralWn Pharmaceuticals Ltd.2001-11-232009-09-28Canada
B-complex-50 TabTabletOralJr Carlson Labs Inc1998-10-252005-09-15Canada
B-nexaTabletOralUpsher Smith Laboratories2011-12-08Not applicableUs
B-plexTabletOralWn Pharmaceuticals Ltd.1999-10-202000-01-28Canada
B-plex 100Injection, solutionIntramuscular; IntravenousMerit Pharmaceuticals2012-01-01Not applicableUs
B-plus - TabTabletOralChampion's Choice Advanced Nutrition Inc.1997-06-111999-08-28Canada
B50 B Complex TabTabletOralNutristar Health Products (1987) Inc.1983-12-311996-09-09Canada
B50 ComplexCapsuleOralPreferred Nutrition Inc.2003-10-292005-08-04Canada
B6 Plus TabTabletOralVita Health Products Inc1979-12-312002-08-01Canada
B6-niacinamide TabTabletOralStandard Process Inc.Not applicableNot applicableCanada
B6, B12 & Folic AcidCapsuleOralNatural Factors Nutritional Products Ltd.2001-12-192009-09-28Canada
B6, B12 & Folic Acid Multi-vitamin TabletsTabletOralWampole Brands2000-02-242009-06-19Canada
BacminTablet, coatedOralMarnel Pharmaceuticals, Llc2000-04-01Not applicableUs
BaisixTabletOralProdemdis Enr.Not applicableNot applicableCanada
Balanced B 125 SrtTablet, extended releaseOralAnabolic Laboratories Inc.1981-12-311996-10-02Canada
Balanced B-100 B-complex Vitamins TabTabletOralPharmavite1991-12-312003-07-30Canada
Balanced B-100 Timed ReleaseTabletOralPharmavite2000-10-242005-07-15Canada
Balanced B-50 B-complex Vitamins TabTabletOralPharmavite1995-12-312000-08-24Canada
Balanced B-50 B-complex Vitamins, Timed ReleTabletOralPharmavite1995-12-312006-07-05Canada
Balanced B-50 ComplexTabletOralLeiner Health ProductsNot applicableNot applicableCanada
Balanced B-complex Vit + Vit C&e TabTabletOralPharmavite1991-12-312006-07-05Canada
Balanced B100TabletOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Balanced B50 ComplexTabletOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Beminal W C Fortis InjPowder, for solutionIntramuscular; IntravenousAyerst Laboratories1951-12-311996-09-10Canada
Beminal With C Fortis CapCapsuleOralWyeth Ayerst Canada Inc.1994-12-312001-08-03Canada
Beminal With C Fortis PwsPowder, for solutionIntravenousWyeth Ayerst Canada Inc.1994-12-312000-08-02Canada
Bev B-150TabletOralBeverly International Nutrition1986-12-311998-08-01Canada
Bio-fenCapsuleOralLisa & Gerry Freundl2001-10-102006-09-28Canada
BiosculptSolutionOralMaxion Nutrition Corp.2002-06-102004-07-20Canada
Bugs Bunny and Friends Multiple VitaminsTabletOralBayer Inc Consumer Care1996-12-312004-04-15Canada
Bugs Bunny Chew Multi Vit Plus IronTabletOralMiles Inc. Pharmaceutical Division1983-12-311996-09-09Canada
C 106 TabTabletOralNf Formulas Inc.1983-12-312001-09-18Canada
C-apnto-B6 Vitamins W Magnesium TabTabletOralMetagenics, Inc.1989-12-311996-10-02Canada
C-B ComplexTabletOralAvacare, Division Of Jeunique International Inc.1984-12-311996-09-09Canada
C-forceCapsuleOralPrairie Naturals1997-04-012002-06-21Canada
C-nate DHACapsule, gelatin coatedOralCenturion Labs2013-01-01Not applicableUs
C.A.G. TabTabletOralNutrition For Life International1996-11-272000-08-11Canada
C.R.D.-forceCapsuleOralPrairie Naturals2001-09-192006-09-20Canada
C.R.T. X Multivitamin & Mineral Powder MixPowderOralMetaform Ltd.1998-12-082001-07-23Canada
Cal M TabTabletOralAnabolic Laboratories Inc.1978-12-312004-03-15Canada
Calcium Folic Acid Plus D ChewableWaferOralAcella Pharmaceuticals, LLC2010-03-23Not applicableUs
Carbassist TabletsTabletOralWyeth Ltd.1978-12-312006-07-24Canada
CarbawayTabletOralAbundance Marketing Ltd.2000-04-122007-07-26Canada
Carthaphy CapCapsuleOralPhyto Health Corporation1973-12-312003-11-27Canada
Cda-21 Vitamins With Non-medicinal Probiotic ComplexCapsuleOralRx Vitamins Inc.2006-08-012007-10-25Canada
Cedevita Plus Vitamin SupplementPowderOralPliva, Pharmaceutical, Chemical, Food And Cosmetic Industry, Inc.Not applicableNot applicableCanada
Cedevita Sugar-free Vitamin SupplementPowderOralPliva, Pharmaceutical, Chemical, Food And Cosmetic Industry, Inc.Not applicableNot applicableCanada
Cell Power Boosting EssenceCreamTopicalMicell Korea Co.,ltd2017-03-20Not applicableUs
Central-vite 18 EssentialTabletOralVita Health Products Inc1998-04-242002-07-31Canada
Century CompleteTabletOralVita Health Products Inc1998-03-172002-07-31Canada
Chela Zinc PlusTabletOralNu Life Nutrition Ltd.1987-12-312000-03-03Canada
Chew.multiple Vits.with Extra C for ChildrenTabletOralRandle Pharmaceutical Inc.1996-09-191999-09-03Canada
Chewable Multiple Vit Plus Iron for ChildrenTabletOralRandle Pharmaceutical Inc.1996-09-191999-09-03Canada
Chewable Multiple Vitamins for ChildrenTabletOralRandle Pharmaceutical Inc.1996-09-191999-09-03Canada
Chewable Multiple Vitamins Plus Extra CTabletOralRandle Pharmaceutical Inc.1993-12-311999-09-03Canada
Chewable Multiple Vitamins Plus Iron TabTabletOralRandle Pharmaceutical Inc.1993-12-311999-09-03Canada
Chewable Multiple Vitamins TabTabletOralRandle Pharmaceutical Inc.1993-12-311999-09-03Canada
Chewable MultivitaminsTabletOralWn Pharmaceuticals Ltd.2002-05-312008-07-17Canada
Chewable Multivitamins Plus IronTabletOralWn Pharmaceuticals Ltd.2002-05-312007-08-07Canada
Children Choice Multivit Chewable TabTabletOralSwiss Herbal Remedies Ltd.1990-12-312009-08-04Canada
Children Choice Multivitamin W Iron Chew TabTabletOralSwiss Herbal Remedies Ltd.1991-12-312009-08-04Canada
Children's Chewable Multi Vit W IronTabletOralShoppers Drug Mart Inc.1982-12-311997-08-15Canada
Children's Chewable Multi VitaminsTabletOralShoppers Drug Mart Inc.1982-12-311997-08-15Canada
Children's Chewable Multi Vitamins With Iron TabletsTabletOralVita Health Products Inc1998-05-202008-08-05Canada
Children's Chewable Multi-vitaminTabletOralWn Pharmaceuticals Ltd.2000-03-012007-08-07Canada
Children's Chewable Multi-vitamin Complete With MineralsTabletOralWn Pharmaceuticals Ltd.2000-03-012001-07-18Canada
Children's Chewable Multiple Vit.plus IronTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1997-10-102002-07-31Canada
Children's Chewable Multiple Vitamins - TabTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1997-10-102002-07-31Canada
Children's Chewable Multiple Vitamins (chewable Tablets)TabletOralPharmetics (2011) Inc.1999-08-162009-07-30Canada
Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets)TabletOralPharmetics (2011) Inc.1999-08-162009-07-30Canada
Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets)TabletOralPharmetics (2011) Inc.1999-08-162009-07-30Canada
Children's Vitamins ChewableTabletOralVita Health Products Inc1990-12-312002-07-31Canada
Children's Vitamins W Iron ChewableTabletOralVita Health Products Inc1990-12-312002-07-31Canada
Childrens Chew Multi Vitamin TabTabletOralNutristar Health Products (1987) Inc.1983-12-311996-09-09Canada
Childrens Chewable Multiple VitaminsTabletOralKsl Pharmaceuticals1994-12-311999-08-12Canada
Childrens Chewable Multiple Vitamins Plus FeTabletOralKsl Pharmaceuticals1994-12-312000-08-29Canada
Childrens Chewable Multiple Vitamins TabTabletOralPharmavite1987-12-312000-08-24Canada
Childrens Chewable MultivitaminsTabletOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Childrens Chewable Multivitamins W IronTabletOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Childrens Chewable Vitamin TabTabletOralPharmetics (2011) Inc.1993-12-312006-07-27Canada
Childrens Chewable VitaminsTabletOralD.C. Labs Limited1974-12-312003-07-11Canada
Childrens Multiple Vit and Min Chew TabTabletOralCountry Health Laboratories Ltd.1982-12-312008-07-17Canada
Citranatal B-calmKitMission Pharmacal2010-02-10Not applicableUs
Citranatal DHATabletOralMission Pharmacal2007-11-20Not applicableUs
Citranatal Harmony 3.0Capsule, gelatin coatedOralMission Pharmacal2014-03-21Not applicableUs
Citranatal RxTabletOralMission Pharmacal2014-08-11Not applicableUs
Complete Mega BTabletOralGahler Enterprises Ltd.1985-12-312001-07-26Canada
Complete Multivitamins and Minerals for ChildrenTabletOralQuest Vitamins A Div Of Purity Life Health Products2001-01-312004-06-29Canada
Complete Multivitamins and Minerals Tablets Timed ReleaseTablet, extended releaseOralPharmetics (2011) Inc.1999-07-262009-07-30Canada
Complex-75CapsuleOralFrega Inc.1990-12-311999-08-06Canada
Complexe B 75mgTabletOralPharmalab Inc.1994-12-312001-07-30Canada
Complexe B Compose 75TabletOralLes Laboratoires Bio SantÉ Inc.1983-12-311996-09-10Canada
Complexe B-75TabletOralFrega Inc.1998-06-292008-02-13Canada
Concept DHACapsule, liquid filledOralUs Pharmaceutical Corporation2009-06-24Not applicableUs
Concept ObCapsuleOralUs Pharmaceutical Corporation2009-01-01Not applicableUs
Croq-vit Pour EnfantsTabletOralNutrivac Ltee1987-12-311996-09-09Canada
CyroplexTabletOralTherapeutic Foods Co.1987-12-312003-07-16Canada
Daily Energy Brand B-complexCapsuleOralEnzymatic Therapy, Inc.2004-01-012008-07-25Canada
Derma-forceCapsuleOralPrairie Naturals1997-04-012006-09-20Canada
Dermagran Moisturizing SpraySprayTopicalCanadian Medical Supply Inc.1987-12-311996-09-09Canada
Dia-viteTabletOralR & D Laboratories Inc.1997-08-132003-07-16Canada
DiaplexTabletOralNephro Tech, Inc.2002-07-102004-07-23Canada
DiclectinTablet, delayed releaseOralDuchesnay Inc.1983-12-31Not applicableCanada
DiclegisTablet, delayed releaseOralDuchesnay Inc.2013-05-15Not applicableUs55494 0100 10 nlmimage10 b639db2e
DivistaCapsuleOralUs Pharmaceutical Corporation2010-07-10Not applicableUs
Dp 2000CapsuleOralPep Products Inc.1997-06-042006-08-23Canada
Dynam Ampoule Et TabletLiquid; TabletOralCardinaux Enrg Les Produits Naturels1989-12-311996-09-09Canada
E.S.T. ComplexTabletOralAbundance Marketing Ltd.2000-12-062004-06-30Canada
E.V.C. Vitamins TabTabletOralSisu Inc.1985-12-312009-08-04Canada
EC + ComplexCapsuleOralSeroyal International Inc.1998-12-312009-07-06Canada
Efferlife Multivitamins and MineralsTablet, effervescentOralNaturale Science Inc.2001-10-012006-10-10Canada
Energy 80 Prolonged Release TabTablet, extended releaseOralSportscience Labs Inc.1981-12-312002-06-20Canada
Energy Booster EssenceCreamTopicalMicell Korea Co.,ltd2017-03-20Not applicableUs
Enviroflex - TabTabletOralEnviro Tech International Canada1997-09-151999-07-26Canada
EscaviteTablet, chewableOralGm Pharmaceuticals2012-02-01Not applicableUs
Essential B TabletsTabletOralGeneral Nutrition Canada Inc.1997-04-182006-08-03Canada
Evc - LiqLiquidOralSisu Inc.1994-12-312007-07-20Canada
Evc Liquid Vitamins A,c,b6 With Beta Caro&znLiquidOralNf Formulas Inc.1992-12-312008-06-26Canada
Everyday Multiple VitaminsTabletOralD.C. Labs Limited1972-12-312003-07-11Canada
Everyday Multiple Vitamins With IronTabletOralD.C. Labs Limited1972-12-312003-07-11Canada
Extra P.N. Vitamin-mineral Drink MixPowderOralChanges InternationalNot applicableNot applicableCanada
Extra-virt Plus DHACapsule, gelatin coatedOralVirtus Pharmaceuticals2012-12-28Not applicableUs
Ez-flexTabletOralMetagenics, Inc.1997-06-302007-09-07Canada
Fabb TabletsTabletOralMidlothian Laboratories2009-01-01Not applicableUs
Fb FormulaTabletOralWeider Nutrition Group (Canada) Ltd.1998-05-052001-07-23Canada
Fem - ControlTabletOralMetagenics, Inc.1998-01-312005-08-19Canada
Fem - F.S. FormulaTabletOralMetagenics, Inc.1998-01-312005-08-19Canada
Fem - PmtTabletOralMetagenics, Inc.1998-02-252002-10-07Canada
Feminex 300 TabTabletOralSantÉ Naturelle (Ag) LtÉe1986-12-311997-09-09Canada
Feminique W Iron and Calcium TabTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1992-12-311998-08-13Canada
Femitab TabTabletOralLe Groupe Prodeal Ltee1988-12-312009-08-05Canada
Ferra Naka Plus VitaminsLiquidOralNaka Sales Ltd.1999-05-052001-07-23Canada
Flexadyn TabTabletOralNutri Dyn Products Ltd.1976-12-311996-09-09Canada
Flinstones Multiple Plus IronTabletOralMiles Inc. Pharmaceutical Division1971-12-311996-09-09Canada
Flintstones Multiple VitaminsTabletOralBayer Inc Consumer Care1995-12-312004-06-28Canada
Flintstones Multiple Vitamins Plus IronTabletOralBayer Inc Consumer Care1995-12-312004-06-28Canada
Flintstones Multiple Vitamins TabTabletOralMiles Inc. Pharmaceutical Division1970-12-311996-09-09Canada
Flintstones W Extra C TabTabletOralMiles Inc. Pharmaceutical Division1981-12-311996-09-09Canada
Floradix Formula LiqLiquidOralFlora Manufacturing And Distributing Ltd.1979-12-312002-06-05Canada
Floravit - SyrSyrupOralFlora Manufacturing And Distributing Ltd.1995-05-282009-08-05Canada
FlorivaTablet, chewableOralBon Geo Pharmaceuticals, Inc.2015-09-10Not applicableUs
Floriva PlusSolution / dropsOralBon Geo Pharmaceuticals, Inc.2015-12-28Not applicableUs
FolbicTabletOralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-02-19Not applicableUs51991 0384 90 nlmimage10 9c07ce0e
FolcapsTabletOralMidlothian Laboratories2009-01-01Not applicableUs
Folcaps Care OneCapsule, gelatin coatedOralMidlothian Laboratories2009-05-01Not applicableUs
Folcaps Omega-3Capsule, gelatin coatedOralMidlothian Laboratories2011-01-03Not applicableUs
Folet OneCapsule, liquid filledOralPronova Corporation2014-06-01Not applicableUs
Folic Acid PlusTabletOralVita Health Products Inc2000-04-012002-07-31Canada
Foltabs 800TabletOralMayne Pharma2009-01-012019-06-30Us
Foltabs PrenatalTabletOralMidlothian Laboratories2009-01-01Not applicableUs
For Kids Only Chewable Multivit. Plus IronTabletOralKsl Pharmaceuticals1996-12-312002-07-31Canada
For Kids Only Chewable Multivitamins - TabTabletOralKsl Pharmaceuticals1996-12-312002-07-31Canada
Formula 6100 CapCapsuleOralStandard Process Inc.Not applicableNot applicableCanada
Formula Adr-vitamin B2,b6 W Calpan TabTabletOralMetagenics, Inc.1996-12-302006-08-14Canada
Formula BCapsuleOralBalance Plus, Inc.2000-04-192004-08-17Canada
Formula BPTabletOralNutrivention Nutritional ProductsNot applicableNot applicableCanada
Formula Ch. Les.TabletOralAbundance Marketing Ltd.2002-06-032004-06-30Canada
Formula CmTabletOralNutrivention Nutritional ProductsNot applicableNot applicableCanada
Formula CnCapsuleOralBalance Plus, Inc.2000-02-092004-08-17Canada
Formula D.S.TabletOralGolden Pride InternationalNot applicableNot applicableCanada
Formula ECTabletOralBody Wise International LlcNot applicableNot applicableCanada
Formula Est'ro Tab SupportCapsuleOralBalance Plus, Inc.2000-02-172004-08-17Canada
Formula Fe-vitamin and Mineral TabTabletOralMetagenics, Inc.1996-12-292005-08-19Canada
Formula Fm Vitamins & Minerals TabTabletOralMetagenics, Inc.1997-01-272001-10-05Canada
Formula Im-vitamins and Minerals TabTabletOralMetagenics, Inc.1997-01-272006-08-14Canada
Formula JsTabletOralNutrivention Nutritional ProductsNot applicableNot applicableCanada
Formula LfTabletOralNumark Laboratories, Inc.2003-12-152009-07-31Canada
Formula O-care Vitamin and Mineral SupplementTabletOralFor Mor International Inc.2000-03-252002-06-25Canada
Formula Pro-BCapsuleOralBalance Plus, Inc.2000-03-082004-08-17Canada
Formula R TabTabletOralMetagenics, Inc.1997-03-052006-08-29Canada
Formula Statin SupportCapsuleOralBalance Plus, Inc.2000-04-192004-08-17Canada
Formula WbTabletOralNutrivention Nutritional ProductsNot applicableNot applicableCanada
Fortamines 10 CapsulesCapsuleOralRougier Pharma Division Of Ratiopharm Inc1974-12-311999-09-27Canada
Fortamines-10 ComprimesTabletOralRougier Pharma Division Of Ratiopharm Inc1979-12-312003-09-22Canada
Fortaplex InjLiquidIntramuscular; IntravenousKripps Pharmacy Ltd.1979-12-31Not applicableCanada
Fortistress TabTabletOralSantÉ Naturelle (Ag) LtÉe1993-12-312001-07-06Canada
Forty Plus Vitamin SupplementTabletOralGarden State Nutritionals1998-10-162000-06-07Canada
Fusion Activator Formula TabTabletOralL & S Research Corporation1993-12-311996-09-09Canada
Garfield Chewable Multivits Plus Iron TabTabletOralWhitehall Robins Inc.1993-12-312000-07-26Canada
Geritol LiquidLiquidOralGlaxosmithkline Inc1992-12-312002-07-31Canada
Gestamine ComprimesTabletOralLab Nadeau LtÉe, Division Of Technilab Inc.1957-12-311999-09-28Canada
Gesticare DHAKitJazz Pharmaceuticals Commercial Corp.2008-10-01Not applicableUs
Glyco-aide TabTabletOralAvant Garde, Les SupplÉments1995-12-311998-07-08Canada
H. Formula - TabTabletOralAbundance Marketing Ltd.1998-01-051999-08-06Canada
Harvest Of Values All B Complex TabTabletOralHillestad Pharmaceuticals Usa1997-09-242009-09-22Canada
Healthy Mamabe Well Rounded Be Well RoundedTablet, film coatedOralMATERNAL SCIENCE, LLC2013-07-09Not applicableUs
Hemarexin TabTabletOralLab Bio Chimique Inc.,Division Of Technilab Pharma Inc.1997-12-172004-08-03Canada
Hemenatal OBTabletOralWh Nutritionals, Llc2012-03-08Not applicableUs
Hi Potency B Complex W Chelated MineralsTabletOralKlaire Labs Inc.1984-12-312004-01-19Canada
Hi Potency B52 B Complex TabTabletOralCountry Health Laboratories Ltd.1982-12-312001-07-27Canada
Hi Potency Balanced B-100 Complex - TabTabletOralLeiner Health ProductsNot applicableNot applicableCanada
Hi Potency Stress B Tension With CTabletOralLee Adams Laboratories1982-12-312010-08-05Canada
High Potency Vitamin B Complex + C TabTabletOralVita Health Products Inc1996-10-112004-07-26Canada
Hill.viteTabletOralHillestad Pharmaceuticals Usa2001-11-142009-09-22Canada
Homosistrol CapsulesCapsuleOralMacromed Pharmicia Inc.Not applicableNot applicableCanada
Hypo Vites TabTabletOralPharmetics (2011) Inc.1977-12-312006-07-27Canada
Iberet 500Tablet, extended releaseOralAbbott1965-12-312007-07-31Canada
IfbTabletOralVisiontel2002-11-082004-03-19Canada
Inatal AdvanceTablet, coatedOralNnodum Pharmaceuticals2005-06-10Not applicableUs
Inatal UltraTablet, coatedOralNnodum Pharmaceuticals2005-06-20Not applicableUs
Infantol DropsSolution / dropsOralChurch & Dwight Company, Inc.1988-12-312008-07-30Canada
Infuvite Adult Multiple VitaminsInjection, solutionIntravenousSandoz2005-05-18Not applicableUs
Insur-all Vitamin SupplementTabletOralGarden State Nutritionals1998-10-162000-06-07Canada
Integra PlusCapsuleOralUs Pharmaceutical Corporation2009-04-27Not applicableUs
Iron 25mg With Vit B-cmplx, Vit C, Cu & MoCapsuleOralQuest Vitamins A Div Of Purity Life Health Products1996-07-232002-07-29Canada
Iron Polysaccharides Folic Acid DHATablet, film coatedOralVirtus Pharmaceuticals2013-12-202017-08-11Us
Iron Vitamins B6,b12,c,folic Acid TabTabletOralLaboratoire Lalco Inc.1989-12-311997-07-31Canada
Isotamine B 300TabletOralValeant Canada Lp Valeant Canada S.E.C.1967-12-31Not applicableCanada
Isotonix Advanced B-complex Vitamins With Potassium and MagnesiumPowderOralMarket America2004-01-272009-07-20Canada
Kanga Sport Vitamins B & C Plus MineralsTablet, effervescentOralLacombe Drugs (1992) LtdNot applicableNot applicableCanada
Kanga-B Vitamin B Group + CTablet, effervescentOralLacombe Drugs (1992) LtdNot applicableNot applicableCanada
Kanga-kid Multi-vitamin & MineralTablet, effervescentOralLacombe Drugs (1992) LtdNot applicableNot applicableCanada
Kanga-kid Vitamins & IronTablet, effervescentOralLacombe Drugs (1992) LtdNot applicableNot applicableCanada
Kanga-V Multivitamins & MineralsTablet, effervescentOralLacombe Drugs (1992) LtdNot applicableNot applicableCanada
Kenwood Liquid SupplementLiquidOralKenwood Laboratories (Division Of Bradley Pharmaceuticals)Not applicableNot applicableCanada
Kid's Choice Children's Chewable Vitamins - TabTabletOralVita Health Products Inc1998-04-162002-07-31Canada
Kidmag Vitamins W Magnesium TabTabletOralMetagenics, Inc.1989-12-311996-10-02Canada
Kids Stuff TabletsTabletOralVita Health Products Inc1998-04-202002-07-31Canada
Kids Stuff With Iron TabletsTabletOralVita Health Products Inc1998-04-202002-07-31Canada
Kimchi Vitamin Chewable MultivitaminTablet, chewableOralTobico2010-03-18Not applicableUs
KindervitesSolution / dropsOralHerbalife International Of America1984-12-312002-09-17Canada
Kmg PlusCapsuleOralSeroyal International Inc.1994-12-312009-07-06Canada
L.I.P. ComplexTabletOralAbundance Marketing Ltd.2000-12-062004-06-30Canada
Leritone JuniorCapsuleOralInstitut De Recherche Biologique Yves Ponroy Canada Inc.1998-12-072004-12-23Canada
Lipo-B-C TabTabletOralMetagenics, Inc.1989-12-311996-10-02Canada
LipovitanLiquidOralP.S.W.C. Co., Inc.1999-01-212005-10-19Canada
Liqui B ComplexLiquidOralTwin Laboratories Inc.1995-12-311999-11-10Canada
Liqui B Complex PlusLiquidOralTwin Laboratories Inc.1995-12-311999-11-10Canada
Liqui Infant VitaminsLiquidOralTwin Laboratories Inc.1995-12-311999-11-10Canada
Liqui VitaLiquidOralTwin Laboratories Inc.1995-12-311999-11-10Canada
Liquid B Complex 50LiquidOralJamieson Laboratories Ltd1985-12-311997-08-13Canada
Livron Plus AmpouleLiquidOralMedic Laboratory LtÉe1980-12-311996-09-09Canada
Livron Plus TabTabletOralMedic Laboratory LtÉe1980-12-311996-09-09Canada
Low Potency B Complex TabTabletOralFlora Manufacturing And Distributing Ltd.1983-12-311999-10-18Canada
Lysamine Diet Supp Amp-tabLiquid; TabletOralWelcker Lyster Ltd., Division Of Technilab Inc.1983-12-311999-09-17Canada
M.V.I. 12LiquidIntravenousAventis Pharma Ltd.1992-12-312002-07-29Canada
M.V.I. PaediatricLiquidIntravenousAventis Pharma Ltd.1988-12-312002-07-29Canada
M.V.I. PediatricInjection, powder, lyophilized, for solutionIntravenousHospira Worldwide, Inc.1983-04-06Not applicableUs
Magnesium 50mg With Vitamin B6 TabTabletOralJamieson Laboratories Ltd1994-12-311996-09-10Canada
Maltlevol 12 LiqLiquidOralCarter Horner Corp.1978-12-312002-02-07Canada
Maltlevol LiqLiquidOralCarter Horner Corp.1980-12-312005-03-21Canada
MangadynTabletOralNutri Dyn Products Ltd.1982-12-311997-08-22Canada
Maxi 10 TabTabletOralDesbergers LtÉe, Division Of Technilab Inc.1979-12-311999-09-17Canada
Medi Wrinkle SerumCreamTopicalMicell Korea Co.,ltd2017-03-20Not applicableUs
Mega 13 Multivitamin FormulaCapsuleOralVita Health Products Inc1988-12-311998-07-22Canada
Megavites TabTabletOralIcn Pharmaceuticals1973-12-312005-04-26Canada
Meplex T 750TabletOralMedic Laboratory LtÉe1966-12-311996-09-09Canada
Meth-X Vitamin and Mineral SupplementCapsuleOralDymatize Enterprises Inc.2002-01-102006-10-06Canada
MethaverCapsuleOralSterling Knight Pharmaceuticals, Llc2015-11-24Not applicableUs
Min-chex CapCapsuleOralStandard Process Inc.Not applicableNot applicableCanada
Mini-B TabTabletOralTwin Laboratories Inc.1995-12-311999-11-10Canada
Mnps Formula SupplementTabletOralGarden State NutritionalsNot applicableNot applicableCanada
Mor-vites TabTabletOralPharmetics (2011) Inc.1992-12-312006-07-27Canada
Multi - N.T.O.x Formula - TabTabletOralAbundance Naturally LtdNot applicableNot applicableCanada
Multi 12 InjectionLiquidIntravenousSandoz Canada Incorporated1994-12-31Not applicableCanada
Multi BTabletOralSeroyal International Inc.1988-12-312009-07-06Canada
Multi Enfants TabTabletOralVitalab1992-12-311997-07-22Canada
Multi Nt-OXTabletOralAbundance Marketing Ltd.1999-02-012001-07-10Canada
Multi RolLiquid; TabletOralRolmex International Inc.1975-12-311997-08-08Canada
Multi Vitamin - MineralTabletOralEnrich International1999-11-112001-09-28Canada
Multi Vitamin & MineralsTabletOralWn Pharmaceuticals Ltd.2002-01-042008-07-17Canada
Multi Vitamin and FluorideSolution / dropsOralLibertas Pharma, Inc.2011-05-21Not applicableUs
Multi Vitamin Drops With FluorideSolution / dropsOralSeton Pharmaceuticals2014-04-18Not applicableUs
Multi Vitamin Drops With Fluoride and IronSolution / dropsOralSeton Pharmaceuticals2014-04-18Not applicableUs
Multi Vitamin Drops With Fluoride With IronLiquidOralStratus Pharmaceuticals2014-09-01Not applicableUs
Multi Vitamin Plus IronTabletOralWn Pharmaceuticals Ltd.2002-03-132009-09-28Canada
Multi Vitamin With FluorideTablet, chewableOralQualitest2009-10-092016-10-13Us
Multi Vitamin, Iron and FluorideSolution / dropsOralMayne Pharma2011-05-212019-10-31Us
Multi Vitamines - LiqLiquidOralLand Art Inc.1995-12-312008-06-26Canada
Multi Vitamins & MineralsTabletOralWn Pharmaceuticals Ltd.2000-01-122001-04-12Canada
Multi Vite Liq AdultLiquidOralPharmetics (2011) Inc.1981-12-312001-07-26Canada
Multi Vite Liq JuniorLiquidOralPharmetics (2011) Inc.1981-12-312001-07-26Canada
Multi-11SolutionIntravenousSandoz Canada Incorporated2002-01-28Not applicableCanada
Multi-12 PediatricLiquidIntravenousSabex Inc1998-04-092009-11-26Canada
Multi-12/k1 PediatricLiquidIntravenousSandoz Canada Incorporated2000-11-07Not applicableCanada
Multi-vit With FluorideSolutionOralA S Medication Solutions1997-04-182017-06-20Us
Multi-vit With Fluoride and IronSolutionOralQualitest1998-01-07Not applicableUs
Multi-vitaminLiquidOralLLC Federal Solutions2013-08-12Not applicableUs
Multi-vitamin Dietary SupplementTabletOralGarden State Nutritionals1998-09-222000-06-07Canada
Multi-vitamin Drops With Fluoride and IronLiquidOralMethod Pharmaceuticals2017-02-24Not applicableUs
Multi-vitamin FluorideLiquidOralStratus Pharmaceuticals2014-09-01Not applicableUs
Multi-vitamin Fluoride and Iron DropsSolutionOralBoca Pharmacal, Inc.2011-04-202015-12-29Us
Multi-vitamin Fluoride DropsSolutionOralH.J. Harkins Company2011-05-04Not applicableUs
Multi-vitamin With FluorideTablet, chewableOralGolden State Medical Supply2010-12-17Not applicableUs
Multi-vitamines Enfants ComprimeTabletOralHerbes Universelles Inc.1997-09-292009-07-15Canada
Multi-vitaminsTabletOralWn Pharmaceuticals Ltd.1999-12-222008-07-17Canada
Multi-vitamins With MineralsTabletOralWn Pharmaceuticals Ltd.2001-04-122009-09-28Canada
Multiple Vitamin Plus Minerals TabTabletOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Multiple Vitamin TabTabletOralAdams Laboratories1983-12-312009-12-02Canada
Multiple VitaminsTabletOralGfr Pharma Ltd.2002-10-102007-07-20Canada
Multiple Vitamins & Minerals TabletsTabletOralPharmetics (2011) Inc.2002-12-182006-07-27Canada
Multiple Vitamins and Minerals TabTabletOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Multiple Vitamins Plus Iron for WomenTabletOralPharmetics (2011) Inc.1999-08-162006-07-27Canada
Multiple Vitamins Plus Iron TabTabletOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Multiple Vitamins TabTabletOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Multiple Vitamins W Minerals TabTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1976-12-312002-07-31Canada
Multiple Vitamins With IronTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1987-12-312002-07-31Canada
Multiple Vitamins With Minerals TabletsTabletOralPharmetics (2011) Inc.1999-07-162009-07-30Canada
MultisolLiquidOralLes Laboratoires Vachon Inc.1979-12-311997-02-06Canada
Multivit Et Fer Ampoules Et ComprimesLiquid; TabletOralNobel Pharm Enr.1988-12-311998-08-14Canada
Multivit-liqLiquidOralPharmalab Inc.1995-12-311997-08-08Canada
MultivitaminTabletOralLaboratoires Confab IncNot applicableNot applicableCanada
Multivitamin Drops With FluorideSolution / dropsOralSancilio & Company, Inc.2017-04-10Not applicableUs
Multivitamin With FluorideTablet, chewableOralPure Tek Corporation2011-06-01Not applicableUs
MultivitaminesTabletOralRolmex International Inc.1998-05-112007-07-09Canada
Multivitamines Et MinerauxTabletOralLe Groupe M. Vachon Inc.Not applicableNot applicableCanada
Multivitamines Et Mineraux Junior RegulierTabletOralLaboratoire Riva Inc1996-10-082008-07-30Canada
Multivitamines Et Mineraux Reguliers / Regular Multivitamins and MineralsTabletOralVita Health Products Inc1998-10-062004-07-26Canada
Multivitamines Plus Fer Pour Enfants (chewable Tablets)TabletOralLaboratoire Lalco Inc.1998-07-032002-09-05Canada
Multivitamines Pour Enfants (chewable Tablets)TabletOralLaboratoire Lalco Inc.1998-07-032002-09-05Canada
Multivitamins and Minerals - CompleteTabletOralVita Health Products Inc2000-02-012006-07-31Canada
Multivitamins and Multiminerals Formula Regular TabletTabletOralPharmetics (2011) Inc.2001-11-222009-07-30Canada
Multivitamins for ChildrenTabletOralQuest Vitamins A Div Of Purity Life Health Products2001-01-312004-06-29Canada
Multivitamins W IronTabletOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Munit-E TabletTabletOralHolista Health (Canada) Inc.1996-12-312002-08-06Canada
MvcTablet, chewableOralSancilio & Company Inc.2009-12-20Not applicableUs
Mvc-fluorideTablet, chewableOralSancilio & Company Inc.2011-12-07Not applicableUs
Myhephron Dialysis and Stress SupplementCapsuleOralMartin Ekwealor Pharmaceu2016-08-01Not applicableUs
Mynephrocaps Dialysis/stress Vitamin SupplementCapsuleOralMartin Ekwealor Pharmaceuticals, Inc.2013-12-16Not applicableUs
N.E.U. ComplexTabletOralAbundance Marketing Ltd.2000-12-042004-06-30Canada
N.U.T. ComplexTabletOralAbundance Marketing Ltd.2000-12-062004-06-30Canada
Nata KompleteTabletOralWh Nutritionals, Llc2011-06-252016-12-06Us
NatafortTabletOralMission Pharmacal2011-08-25Not applicableUs
NataviteTabletOralSchein Pharmaceutical Canada Inc.1997-07-292004-07-26Canada
Natelle OneCapsule, gelatin coatedOralMeda Pharmaceuticals Ltd2015-02-01Not applicableUs
Neo Bex ElixirElixirOralNeolab Inc1984-12-311997-08-12Canada
Neo-bexTabletOralNeolab Inc1987-12-312005-08-02Canada
Neo-bex InjectableSolutionIntramuscular; IntravenousBrostel Inc.1951-12-31Not applicableCanada
NephrocapsCapsule, liquid filledOralCardinal Health2010-01-14Not applicableUs
Nestabs OneCapsule, gelatin coatedOralWomens Choice Pharmaceuticals, Llc2017-07-20Not applicableUs
Neutral C + Coenzyme Q10 Plus Vitamins & MineralsCapsuleOralNew Vision Nutritionals Company1998-06-072002-11-20Canada
Nexa PlusCapsuleOralUpsher Smith Laboratories2012-08-01Not applicableUs
Nexa Select Rx Prenatal Vitamin With Plant-based DHACapsuleOralUpsher Smith Laboratories2012-12-17Not applicableUs
Niaacinamide Azelaic Ac Turmer Fa B6 Zinc Ox CopperTablet, coatedOralVirtus Pharmaceuticals2014-05-092017-08-03Us
Niacex B6CapsuleOralTherapeutic Foods Co.1994-05-182005-07-20Canada
Niacinamide-B6 CapCapsuleOralStandard Process Inc.Not applicableNot applicableCanada
NuferaTabletOralCarwin Associates, Inc2015-12-16Not applicableUs
Nutrilite Double XTabletOralNutrilite, A Division Of Access Business Group, Llc2002-12-152008-06-24Canada
Nutrol-B-complexTabletOralRolmex International Inc.1999-06-282008-07-09Canada
O-cal Fa MultivitaminTabletOralPharmics, Inc.1970-01-15Not applicableUs
O-cal Prenatal VitaminTabletOralPharmics, Inc.2002-01-23Not applicableUs
OnccorTabletOralSimone Protective Pharmaceuticals, Inc.Not applicableNot applicableCanada
One A Day Advance AdultsTabletOralBayer Inc Consumer Care2002-09-122007-08-02Canada
One A Day Advance Adults 50+TabletOralBayer Inc Consumer Care2002-09-122007-08-02Canada
One A Day Advance FemTabletOralBayer Inc Consumer Care1999-03-012001-02-22Canada
One A Day TabTabletOralCountry Health Laboratories Ltd.1982-12-312001-07-27Canada
Orange Flavored Crystal Chews TabTabletOralJeunique International Inc.1998-02-172006-07-20Canada
Orifer FTabletOralSanofi Aventis1995-12-312007-11-22Canada
Original Bioscal Forte Multi-vitamin Supplement CapsulesCapsuleOralCarram Inc.1997-05-071999-07-30Canada
Orti BCapsuleOralSeroyal International Inc.1983-12-312008-10-09Canada
P & Sp Special FormulaCapsuleOralNutraceutical Corporation2005-11-012006-09-18Canada
P.N.P. Vitamin DrinkLiquidOralChanges InternationalNot applicableNot applicableCanada
P.R.O. ComplexTabletOralAbundance Marketing Ltd.2000-12-062004-06-30Canada
Paramettes Chewable Multivitamins Plus IronTabletOralWyeth Ayerst Canada Inc.1994-12-312000-08-02Canada
Paramettes Chewable Multivits With Iron TabTabletOralWhitehall Robins Inc.1994-12-311996-09-09Canada
Paramettes Multivits Plus Iron Tab (teens)TabletOralWhitehall Robins Inc.1993-12-311996-09-09Canada
Paramettes SyrupSyrupOralWyeth Ayerst Canada Inc.1994-12-312002-07-31Canada
Pediatric Infuvite Multiple VitaminsInjection, solutionIntravenousSandoz2001-02-21Not applicableUs
Pediatric Infuvite Multiple Vitamins for InfusionInjection, solutionIntravenousSandoz2001-02-21Not applicableUs
Perfect Wrinkle SerumCreamTopicalMicell Korea Co.,ltd2017-03-20Not applicableUs
Perioe Lucky Fresh - Cavity CarePasteDentalLg Household & Health Care Ltd.2010-04-26Not applicableUs
Phosthenine Vitamines Et Fer (ampoules Buvable)LiquidOralLaboratoires Cortunon Inc.1997-01-232007-07-23Canada
Phytofortis + Calcium A-DLiquid; TabletOralPhyto Health Corporation1983-12-312003-11-27Canada
Phytoplex B LiqLiquidOralPhyto Health Corporation1973-12-312004-08-30Canada
PhytopureCapsuleOralLaboratoire Lalco Inc.1993-12-312001-10-15Canada
PM CapsCapsuleOralNew Vision Nutritionals Company1998-10-012002-11-20Canada
PMS-doxylamine-pyridoxineTablet, delayed releaseOralPharmascience Inc2017-07-10Not applicableCanada
PNF-FirstTablet, coatedOralAcella Pharmaceuticals, LLC2013-05-17Not applicableUs
Pnv Ferrous Fumarate Docusate Folic AcidTabletOralVirtus Pharmaceuticals2014-04-22Not applicableUs
Pnv Prenatal Plus MultivitaminTabletOralClinical Solutions Wholsesale2013-04-012017-07-03Us
Pnv Prenatal VitaminTablet, chewableOralSancilio & Company Inc.2011-12-20Not applicableUs
Pnv Prenatal Vitamin Plus Vitamin ATabletOralSancilio & Company Inc.2012-12-07Not applicableUs
Pnv-dhaCapsule, gelatin coatedOralAcella Pharmaceuticals, LLC2009-11-02Not applicableUs
Pnv-selectTablet, film coatedOralAcella Pharmaceuticals, LLC2009-11-02Not applicableUs
Polymine Avec Zinc Et CuivreTabletOralLes Laboratoires Vachon Inc.1985-12-312007-07-12Canada
Pour Ma SantéTabletOralProdemdis Enr.Not applicableNot applicableCanada
Powertech Vitamin and Mineral SupplementPowderOralDymatize Enterprises Inc.2002-09-182006-10-06Canada
Prefera Ob Plus DHATabletOralAlaven Pharmaceutical2009-04-01Not applicableUs
PreferaobTablet, coatedOralMeda Pharmaceuticals Ltd2015-04-28Not applicableUs
Preferaob OneCapsule, liquid filledOralMeda Pharmaceuticals Ltd2015-04-28Not applicableUs
Preferaob Plus DHATabletOralAlaven Pharmaceutical2010-11-15Not applicableUs
PregvitTabletOralDuchesnay Inc.2003-08-252016-07-05Canada
Pregvit Folic 4TabletOralDuchesnay Inc.Not applicableNot applicableCanada
Pregvit Folic 5TabletOralDuchesnay Inc.2006-03-172016-07-05Canada
PremelTabletOralLe Naturiste J.M.B. Inc.2002-10-312008-07-31Canada
Prenaissance PlusCapsule, liquid filledOralAcella Pharmaceuticals, LLC2011-09-12Not applicableUs
Prenatal 19Tablet, coatedOralNationwide Laboratories2013-06-01Not applicableUs
Prenatal Mega AntioxidantTabletOralUsana Health Services, Inc.2012-04-11Not applicableUs
Prenatal PlusTablet, film coatedOralBlenheim Pharmacal, Inc.2010-12-09Not applicableUs65162 0668 50 nlmimage10 120e0910
Prenatal Plus IronTablet, film coatedOralMajor2011-06-07Not applicableUs
Prenatal Vitamins PlusTabletOralbryant ranch prepack2011-04-15Not applicableUs
Prenatal Vitamins Plus Low IronTabletOralPatrin Pharma2013-04-01Not applicableUs39328 0106 10 nlmimage10 df476fdb
Prenatal, DHAKitPure Tek Corporation2017-08-10Not applicableUs
Prenate AmTablet, coatedOralAvion Pharmaceuticals, Llc2013-06-15Not applicableUs
Prenate EliteTablet, coatedOralAvion Pharmaceuticals, Llc2012-08-06Not applicableUs
Prenate EnhanceCapsule, gelatin coatedOralAvion Pharmaceuticals, Llc2013-09-17Not applicableUs
Prenate EssentialCapsule, gelatin coatedOralAvion Pharmaceuticals, Llc2014-07-18Not applicableUs
Prenate PixieTablet, film coatedOralAvion Pharmaceuticals, Llc2014-08-14Not applicableUs
Prenate RestoreCapsule, gelatin coatedOralAvion Pharmaceuticals, Llc2013-09-17Not applicableUs
Prenate StarTablet, coatedOralAvion Pharmaceuticals, Llc2014-06-05Not applicableUs
PreplusTabletOralVirtus Pharmaceuticals2014-04-04Not applicableUs
PretabTabletOralVirtus Pharmaceuticals2014-04-092017-08-08Us
Prevital TabTabletOralBio Vita1991-12-312000-07-20Canada
Pros-gard Zinc and Vitamin B6 - CapsuleCapsuleOralHolista Health (Canada) Inc.1996-12-312002-08-06Canada
ProsgardCapsuleOralHolista Health (Canada) Inc.1996-12-312002-08-06Canada
Purevit Dualfe PlusCapsuleOralPure Tek Corporation2011-06-01Not applicableUs
Q.T. Vitamin and Mineral Drink MixPowderOralGarden State NutritionalsNot applicableNot applicableCanada
Reaphirm Plant Source DHACapsule, gelatin coatedOralEverett Laboratories, Inc.2011-12-05Not applicableUs
Red American Eagle Vitamin Supplement DrinkLiquidOralP.S.W.C. Co., Inc.Not applicableNot applicableCanada
Red BullLiquidOralP.S.W.C. Co., Inc.1999-01-212005-10-19Canada
Redoxon-calTablet, effervescentOralBayer Inc Consumer Care1992-12-312007-08-02Canada
ReebokLiquidOralClearly Canadian Beverage Corporation2003-05-152009-08-06Canada
Reliv So Sense Daily Vitamin SupplementPowder, for solutionOralReliv International Inc.2000-03-242007-07-10Canada
Reno CapsCapsuleOralNnodum Pharmaceuticals2008-11-30Not applicableUs63044 0622 01 nlmimage10 7d3cbea5
ReplaviteTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1999-10-202002-07-31Canada
Revit Plus CapCapsuleOralIcn Pharmaceuticals1972-12-311998-08-13Canada
Revitex Ampoules Et ComprimesLiquid; TabletOralLes Produits Gerbex Inc.1988-12-312005-06-29Canada
Revival 1 TabTabletOralBio Vita1991-12-311999-08-12Canada
Right Choice A.M. Multi Formula - CapletTabletOralBody Wise International LlcNot applicableNot applicableCanada
Se-care ChewableTablet, chewableOralSeton Pharmaceuticals2009-05-012016-10-13Us
Se-natal 19TabletOralSeton Pharmaceuticals2009-07-01Not applicableUs
Se-natal 19 ChewableTablet, chewableOralSeton Pharmaceuticals2009-07-01Not applicableUs
Se-natal OneTabletOralSeton Pharmaceuticals2009-04-162016-10-13Us
Se-tan DHACapsule, gelatin coatedOralSeton Pharmaceuticals2009-10-012016-04-30Us
Se-tan PlusCapsule, gelatin coatedOralSeton Pharmaceuticals2009-10-01Not applicableUs
Shen Min Vitamin SupplementTabletOralBiotech Corporation2002-08-262007-06-25Canada
Sibergin B - CapCapsuleOralPharmavite1996-09-031998-09-08Canada
Snow White AmpouleCreamTopicalMicell Korea Co.,ltd2017-03-20Not applicableUs
SolarayCapsuleOralAhmed's Sunforce International Products Inc.Not applicableNot applicableCanada
Somarexin and C 1000Liquid; TabletOralLaboratoire Lalco Inc.1977-12-312008-07-29Canada
Somavit Brand Vitamins and Minerals ComplexTabletOralSoma Health Products2000-01-152005-08-26Canada
Sopalamine/3b Plus CTabletOralTechnilab Pharma Inc.1987-12-312001-09-05Canada
Sopalamine/3b TabTabletOralTechnilab Pharma Inc.1987-12-312001-09-05Canada
Spd TabTabletOralSeroyal International Inc.1988-12-311996-09-10Canada
Spectrum 2 CapCapsuleOralNf Formulas Inc.1988-12-312008-06-26Canada
Stress B & C CapletTabletOralHealth Wise Nutrition Inc.1995-12-311998-08-25Canada
Stress B Capsules With Vitamin CCapsuleOralRheingold Food International Ltd.1987-12-312007-07-26Canada
Stress B Complex With C, E & IronTabletOralPharmavite1999-10-312005-07-15Canada
Stress B With 1000 Mg Vitamin CTabletOralHolista Health (Canada) Inc.2002-11-132008-07-17Canada
Stress B&c TabTabletOralBioforce Canada Inc.1985-12-311997-04-04Canada
Stress Complex 600 Avec Vit E Cuivre ZincTabletOralFrega Inc.1995-12-312008-02-13Canada
Stress Ctr SrtTablet, extended releaseOralBioenergy Inc.1979-12-311998-06-03Canada
Stress FormulaTabletOralVita Health Products Inc1998-05-202005-07-20Canada
Stress Formula + IronTabletOralVita Health Products Inc1998-05-202006-07-31Canada
Stress Formula B-comp + 500mg Vit C TabTabletOralQuest Vitamins A Div Of Purity Life Health Products1987-12-312002-07-29Canada
Stress Formula Multi-B Comp + 500mg Vit C CapCapsuleOralQuest Vitamins A Div Of Purity Life Health Products1987-12-312001-07-06Canada
Stress Formula Multivitamin Tablets USPTabletOralLeiner Health ProductsNot applicableNot applicableCanada
Stress Formula TabTabletOralNatures Sunshine Products, Inc.1986-12-312009-09-09Canada
Stress Formula Vit B With C ComplexTabletOralWatkins Incorporated1985-12-312000-01-15Canada
Stress Forte Plus Lipotropic FactorsTabletOralDouglas Laboratories1995-12-312009-09-29Canada
Stress TabTabletOralVita Health Products Inc1981-12-312005-07-20Canada
Stress TabletsTabletOralD.C. Labs Limited1981-12-312003-07-11Canada
Stress Vitamin B With C Complex TabletsTabletOralPurity Life Health Products A Division Of Sunopta Inc.2002-06-012007-07-26Canada
StressmatesTabletOralTwin Laboratories Inc.1995-12-311999-11-10Canada
Strovite Forte CapletTablet, coatedOralEverett Laboratories, Inc.1996-10-01Not applicableUs
Strovite One CapletsTabletOralEverett Laboratories, Inc.2001-05-04Not applicableUs
Sun-rype VitaburstLiquidOralSun Rype Products Ltd.2004-08-102008-03-13Canada
Super B Compound W 500mg Vit CTabletOralGahler Enterprises Ltd.1986-12-312000-08-01Canada
Super Charged EnergyPowderOralSimone Protective Pharmaceuticals, Inc.Not applicableNot applicableCanada
Super Daily No 2TabletOralW.R. Enterprises Inc.1990-12-312003-07-30Canada
Super PantoplexTabletOralNu Life Nutrition Ltd.1987-12-312000-03-03Canada
Super Stress CapsulesCapsuleOralRheingold Food International Ltd.1987-12-311997-08-22Canada
Super Stress Mega B Plus 1000mg Vit C TabTabletOralQuest Vitamins A Div Of Purity Life Health Products1987-12-312001-07-06Canada
Super Vitalex Ampoule BuvableLiquidOralCarmaran LtÉe1984-12-312001-08-31Canada
Super-pote Vitamin SupplementTabletOralGarden State Nutritionals1998-09-252000-06-07Canada
Supplement De Multivitamines Infusion Arome Fruits RougesKitOralYves Rocher Inc.1999-10-182000-08-08Canada
Supravite 10ml AmpouleLiquidOralNobel Pharm Enr.1991-12-312002-09-06Canada
Supravite Bouteille 250mlLiquidOralNobel Pharm Enr.2002-10-312008-07-29Canada
Supravite C 1000Liquid; TabletOralNobel Pharm Enr.1981-12-312002-09-06Canada
Supravite Pour EnfantsTabletOralPharmalab Inc.1985-12-312008-07-14Canada
Supravite Stress Avec Vit ETabletOralPharmalab Inc.1985-12-311997-08-08Canada
Supravite Stress Avec Vit E Cuivre Et ZincTabletOralPharmalab Inc.1985-12-311997-08-08Canada
Supravite Stress Avec Vit E Et FerTabletOralPharmalab Inc.1985-12-311997-08-08Canada
Surbex 500 FilmtabTabletOralAbbott1979-12-312008-06-06Canada
Surbex-500 With IronTabletOralAbbott1986-12-312008-06-06Canada
Surbex-500 With ZincTabletOralAbbott1986-12-312008-06-06Canada
Swical-energy-2LiquidOralLes Laboratoires Swisse Inc.1997-06-092006-02-14Canada
T.R.I. B-plex SrcCapsule, extended releaseOralAnabolic Laboratories Inc.1979-12-312004-03-15Canada
Tandem DHACapsuleOralUs Pharmaceutical Corporation2007-01-17Not applicableUs
Tandem ObCapsuleOralUs Pharmaceutical Corporation2006-06-17Not applicableUs
Tandem PlusCapsuleOralUs Pharmaceutical Corporation2006-06-17Not applicableUs
Tar-endCapsuleOralNatures Sunshine Products, Inc.1999-05-252006-07-10Canada
Time Release B 100 Compound - TabletTabletOralHealth Wise Nutrition Inc.1996-10-222002-07-18Canada
Timed Release B Complex 100 SrtTablet, extended releaseOralJamieson Laboratories Ltd1994-12-311997-08-13Canada
Timed Release B-complex 100Tablet, extended releaseOralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
Timed Release B-complex 50Tablet, extended releaseOralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
Tini-cal AmpoulesLiquidOralPharmetics (2011) Inc.1966-12-312001-07-26Canada
Toni Com LiqLiquidOralVitalab1990-12-312009-07-14Canada
Tonicol Et A-D-C Ampoules/comprimesLiquid; TabletOralDistributions Multi Pro Inc.1988-12-311999-07-21Canada
TozalCapsule, gelatin coatedOralFocus Laboratories, Inc.2013-06-012016-10-13Us
Tri AdrenopanCapsule, extended releaseOralAnabolic Laboratories Inc.1980-12-312004-03-15Canada
TriadvanceTabletOralTrigen Laboratories, Inc.2010-09-10Not applicableUs
Tricare PrenatalTablet, coatedOralMedecor Pharma, Llc2002-11-11Not applicableUs
Trinatal GtTabletOralTrigen Laboratories, Inc.2011-07-05Not applicableUs
Twin Ultra Liquid Fruit Punch FlavorLiquidOralTwin Laboratories Inc.1995-12-312002-09-11Canada
Twin Ultra Liquid Grape FlavorLiquidOralTwin Laboratories Inc.1995-12-312007-08-01Canada
Twin Ultra Liquid Lemon-lime FlavorLiquidOralTwin Laboratories Inc.1995-12-312005-08-30Canada
Twin Ultra Liquid Orange FlavorLiquidOralTwin Laboratories Inc.1995-12-312002-09-11Canada
Ultimatecare One NfCapsuleOralTrigen Laboratories, Inc.2009-12-04Not applicableUs
Ultra EnerforceLiquidOralNutribon (1986) Inc.2002-01-292005-02-16Canada
Ultra HrTabletOralNatural Organics Inc.Not applicableNot applicableCanada
Usana Megavitamin Tablets - TabTabletOralUsana Health Sciences, Inc.1996-12-302000-09-11Canada
Vasodyn TabTabletOralNutri Dyn Products Ltd.1978-12-311998-08-13Canada
Viamon Ampoules Et ComprimesLiquid; TabletOralLab Nadeau LtÉe, Division Of Technilab Inc.1977-12-311999-09-28Canada
Vigo Multivitamins Drops/lozengeLozengeOralAshbury Research CorporationNot applicableNot applicableCanada
Vimeral TabTabletOralIcn Pharmaceuticals1979-12-312005-04-26Canada
Virt-capsCapsule, gelatin coatedOralVirtus Pharmaceuticals2014-04-012017-08-11Us
Virt-PNTablet, coatedOralVirtus Pharmaceuticals2012-07-122017-08-09Us
Virt-PN DHACapsule, gelatin coatedOralVirtus Pharmaceuticals2012-07-122017-08-08Us
Virt-PN PlusCapsule, gelatin coatedOralVirtus Pharmaceuticals2013-03-012017-08-08Us
Virt-viteTabletOralVirtus Pharmaceuticals2014-01-04Not applicableUs
Virt-vite PlusTabletOralVirtus Pharmaceuticals2014-01-142017-08-11Us
Vit B Complex CtrTablet, extended releaseOralBioenergy Inc.1979-12-311998-06-03Canada
Vit B Complex Plus Vit C 550mgCapsuleOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Vit-HA Multi Vitamin and Zinc SupplementTabletOralRheingold Food International Ltd.1994-12-312007-07-26Canada
Vita B + C 500 TabTabletOralLaboratoire Romilo1993-12-311999-08-18Canada
Vita B Complex TabTabletOralNutrimetics International (Canada) Inc.1985-12-312000-07-19Canada
Vita Day TabTabletOralJamieson Laboratories Ltd1993-12-311997-08-13Canada
Vita-BTabletOralNutri Dyn Products Ltd.1984-12-311997-08-22Canada
Vita-B-75 CapCapsuleOralLes Laboratoires Vachon Inc.1989-12-311998-09-28Canada
Vita-worth B-complex TabletsTabletOralGeneral Nutrition Canada Inc.1997-04-182005-08-05Canada
Vitabanks Vitamin TabTabletOralVitabank Inc.1990-12-311997-05-30Canada
Vitachrom GcTabletOralNikken Usa, Incorporated2000-08-302007-10-01Canada
VitafantTabletOralLes Laboratoires Vachon Inc.1994-12-312008-07-09Canada
Vitafer - LiqLiquidOralFrega Inc.1995-12-311997-12-10Canada
Vitaflex Dietary SuplementTabletOralHome Shopping Network DirectNot applicableNot applicableCanada
Vitafol CapletCapsuleOralEverett Laboratories, Inc.1985-05-01Not applicableUs
Vitafol NanoTablet, coatedOralEverett Laboratories, Inc.2014-07-14Not applicableUs
Vitafol Ob CapletTabletOralExeltis Usa, Inc.2002-12-02Not applicableUs
Vitafol OneCapsule, gelatin coatedOralEverett Laboratories, Inc.2011-06-13Not applicableUs
Vitafol PlusCapsule, liquid filledOralEverett Laboratories, Inc.2012-04-23Not applicableUs
Vitafol UltraCapsule, liquid filledOralExeltis Usa, Inc.2013-09-23Not applicableUs
Vitalife - CapsuleCapsuleOralHolista Health (Canada) Inc.1996-11-132002-08-06Canada
Vitamin B + C CapCapsuleOralFinlandia Consultants1990-12-311997-12-02Canada
Vitamin B ComplexInjectionIntravenousMylan Institutional2013-05-10Not applicableUs
Vitamin B Complex + C 300mg CapCapsuleOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Vitamin B Complex + C 600mg TabTabletOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Vitamin B Complex 100 TabTabletOralBioforce Canada Inc.1994-12-311997-04-04Canada
Vitamin B Complex 50TabletOralGfr Pharma Ltd.2002-10-102004-06-15Canada
Vitamin B Complex Plus 300mg Vitamin CTabletOralHall Laboratories, Ltd.1996-11-282003-09-11Canada
Vitamin B Complex Plus C 300mg Timed ReleaseTablet, extended releaseOralVita Health Products Inc1998-10-062009-08-06Canada
Vitamin B Complex SupplTabletOralAvacare, Division Of Jeunique International Inc.1985-12-312006-07-20Canada
Vitamin B Complex TabTabletOralNutristar Health Products (1987) Inc.1981-12-311996-09-09Canada
Vitamin B Complex W C 300mg TabTabletOralLee Adams Laboratories1982-12-312009-12-02Canada
Vitamin B Complex W C TabTabletOralAlbi Imports Ltd.1979-12-312004-09-24Canada
Vitamin B Compound TabTabletOralNutrilite, A Division Of Access Business Group, Llc1982-12-311996-09-09Canada
Vitamin B Compound W C Tab 500mgTabletOralAdams Laboratories1979-12-312009-10-21Canada
Vitamin B Compound W Vit C 250mg TabTabletOralSwiss Herbal Remedies Ltd.1972-12-312003-09-10Canada
Vitamin B Compound With Vitamin C Fortis Capsule DtcCapsuleOralD.C. Labs Limited1973-12-312005-07-19Canada
Vitamin B Cpd W Vit C TabTabletOralIcn Pharmaceuticals1978-12-312005-04-26Canada
Vitamin B TabletsTabletOralWeider Health Products1985-12-311999-09-09Canada
Vitamin B6 & B12 With Folic AcidCapsuleOralWn Pharmaceuticals Ltd.2002-05-222009-09-28Canada
Vitamine 110 LiqLiquidOralFrega Inc.1993-12-312008-07-09Canada
Vitamine Du Groupe B Plus Fer - LiqLiquidOralPharmalab Inc.1995-12-312008-07-14Canada
Vitamines Pour Bebes Et EnfantsLiquidOralHerbes Universelles Inc.1978-12-312009-07-15Canada
Vitogen B Compound W C Fortis CapsulesCapsuleOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1972-12-311997-10-14Canada
Vitogen B Stress C Vit E Zinc & CopTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1984-12-312002-07-31Canada
Vitogen B Stress C600TabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1981-12-312002-07-31Canada
Vitogen Multiple Vitamins TabTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1966-12-311997-10-14Canada
Vitogen Multiple Vitamins W IronTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1976-12-311997-10-14Canada
Vitreat Chewable Vitamin TabTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1972-12-311997-08-08Canada
Vitreat Chewable Vitamins Plus IronTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1977-12-311997-08-08Canada
Vp Ch PlusCapsule, gelatin coatedOralVirtus Pharmaceuticals2014-04-09Not applicableUs
Vp Ch UltraCapsule, gelatin coatedOralVirtus Pharmaceuticals2014-04-142017-08-08Us
Vp-CH-pnvCapsuleOralVirtus Pharmaceuticals2012-03-15Not applicableUs
VP-heme OBTablet, film coatedOralVirtus Pharmaceuticals2013-10-14Not applicableUs
VP-heme OneCapsule, gelatin coatedOralVirtus Pharmaceuticals2013-03-01Not applicableUs
Vp-zelTablet, coatedOralVirtus Pharmaceuticals2012-03-01Not applicableUs
Vtb Vitamin and Mineral SupplementTabletOralGarden State NutritionalsNot applicableNot applicableCanada
Women's FormulaTabletOralPro Ma Systems1998-10-312007-09-25Canada
Z-force Vitamin and Mineral SupplementCapsuleOralDymatize Enterprises Inc.2001-12-122006-10-06Canada
Z-mass PM Vitamin and Mineral SupplementCapsuleOralCytodyne Technologies Inc.2001-02-282004-10-22Canada
Zatean-CHCapsuleOralTrigen Laboratories, Inc.2010-11-01Not applicableUs13811 0583 30 nlmimage10 911dc8be
Zinc Plus Vitamin B6 TabTabletOralMetagenics, Inc.1995-12-312001-10-05Canada
Zinc Plus Vitamins C & B6 LozengesLozengeOralVita Plus Industries Inc.Not applicableNot applicableCanada
ZingiberTabletOralPru Gen, Inc. Pharmaceuticals2013-02-01Not applicableUs
Zoo ChewsTabletOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Categories
UNIIKV2JZ1BI6Z
CAS number65-23-6
WeightAverage: 169.1778
Monoisotopic: 169.073893223
Chemical FormulaC8H11NO3
InChI KeyLXNHXLLTXMVWPM-UHFFFAOYSA-N
InChI
InChI=1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3
IUPAC Name
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol
SMILES
CC1=C(O)C(CO)=C(CO)C=N1
Pharmacology
Indication

For the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy.

Structured Indications Not Available
Pharmacodynamics

Vitamin B6 (pyridoxine) is a water-soluble vitamin used in the prophylaxis and treatment of vitamin B6 deficiency and peripheral neuropathy in those receiving isoniazid (isonicotinic acid hydrazide, INH). Vitamin B6 has been found to lower systolic and diastolic blood pressure in a small group of subjects with essential hypertension. Hypertension is another risk factor for atherosclerosis and coronary heart disease. Another study showed pyridoxine hydrochloride to inhibit ADP- or epinephrine-induced platelet aggregation and to lower total cholesterol levels and increase HDL-cholesterol levels, again in a small group of subjects. Vitamin B6, in the form of pyridoxal 5'-phosphate, was found to protect vascular endothelial cells in culture from injury by activated platelets. Endothelial injury and dysfunction are critical initiating events in the pathogenesis of atherosclerosis. Human studies have demonstrated that vitamin B6 deficiency affects cellular and humoral responses of the immune system. Vitamin B6 deficiency results in altered lymphocyte differentiation and maturation, reduced delayed-type hypersensitivity (DTH) responses, impaired antibody production, decreased lymphocyte proliferation and decreased interleukin (IL)-2 production, among other immunologic activities.

Mechanism of action

Vitamin B6 is the collective term for a group of three related compounds, pyridoxine (PN), pyridoxal (PL) and pyridoxamine (PM), and their phosphorylated derivatives, pyridoxine 5'-phosphate (PNP), pyridoxal 5'-phosphate (PLP) and pyridoxamine 5'-phosphate (PMP). Although all six of these compounds should technically be referred to as vitamin B6, the term vitamin B6 is commonly used interchangeably with just one of them, pyridoxine. Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA).

TargetKindPharmacological actionActionsOrganismUniProt ID
Pyridoxal kinaseProteinyes
ligand
HumanO00764 details
Related Articles
Absorption

The B vitamins are readily absorbed from the gastrointestinal tract, except in malabsorption syndromes. Pyridoxine is absorbed mainly in the jejunum.

Volume of distributionNot Available
Protein binding

22%

Metabolism

Hepatic.

Route of eliminationNot Available
Half life

15-20 days

ClearanceNot Available
Toxicity

Oral Rat LD50 = 4 gm/kg. Toxic effects include convulsions, dyspnea, hypermotility, diarrhea, ataxia and muscle weakness.

Affected organisms
  • Humans and other mammals
PathwaysNot Available
Pharmacogenomic Effects/ADRs Not Available
Interactions
Drug Interactions
DrugInteractionDrug group
AltretamineThe therapeutic efficacy of Altretamine can be decreased when used in combination with Pyridoxine.Approved
AmobarbitalThe metabolism of Amobarbital can be increased when combined with Pyridoxine.Approved, Illicit
BarbexacloneThe metabolism of Barbexaclone can be increased when combined with Pyridoxine.Experimental
BarbitalThe metabolism of Barbital can be increased when combined with Pyridoxine.Illicit
FosphenytoinThe metabolism of Fosphenytoin can be increased when combined with Pyridoxine.Approved
HexobarbitalThe metabolism of Hexobarbital can be increased when combined with Pyridoxine.Approved
LevodopaThe therapeutic efficacy of Levodopa can be decreased when used in combination with Pyridoxine.Approved
MethohexitalThe metabolism of Methohexital can be increased when combined with Pyridoxine.Approved
MethylphenobarbitalThe metabolism of Methylphenobarbital can be increased when combined with Pyridoxine.Approved
PentobarbitalThe metabolism of Pentobarbital can be increased when combined with Pyridoxine.Approved, Vet Approved
PhenobarbitalThe metabolism of Phenobarbital can be increased when combined with Pyridoxine.Approved
PhenytoinThe metabolism of Phenytoin can be increased when combined with Pyridoxine.Approved, Vet Approved
PrimidoneThe metabolism of Primidone can be increased when combined with Pyridoxine.Approved, Vet Approved
SecobarbitalThe metabolism of Secobarbital can be increased when combined with Pyridoxine.Approved, Vet Approved
ThiamylalThe metabolism of Thiamylal can be increased when combined with Pyridoxine.Approved, Vet Approved
ThiopentalThe metabolism of Thiopental can be increased when combined with Pyridoxine.Approved, Vet Approved
Food InteractionsNot Available
References
Synthesis Reference

Harumi Kita, "Production of pyridoxine." U.S. Patent US4339586, issued October, 1972.

US4339586
General ReferencesNot Available
External Links
ATC CodesA11HA02 — Pyridoxine (vit b6)
AHFS Codes
  • 88:08.00
  • 92:02.00*
PDB Entries
FDA labelNot Available
MSDSDownload (51.5 KB)
Clinical Trials
Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedNot AvailableHuman Immunodeficiency Virus (HIV) Infections / Infection, Human Immunodeficiency Virus I / Mycobacterium avium complex infection1
1CompletedDiagnosticHealthy Volunteers1
1CompletedOtherHeart Rate / Heart Rate Variability / Inflammatory Reaction1
1CompletedPreventionHIV/AIDS1
1CompletedTreatmentCancers / Metastases1
1CompletedTreatmentHuman Immunodeficiency Virus (HIV) Infections / Tuberculosis1
1Not Yet RecruitingBasic ScienceAging / Mineral deficiency / Vitamin Deficiency1
1, 2Active Not RecruitingTreatmentAdvanced Cancers / Malignant Lymphomas1
1, 2RecruitingTreatmentMalignant Lymphomas1
1, 2SuspendedTreatmentSchizoaffective Disorders / Schizophrenic Disorders1
1, 2TerminatedTreatmentPsoriasis1
1, 2WithdrawnTreatmentMalignant Lymphomas1
2Active Not RecruitingTreatmentHuman Immunodeficiency Virus (HIV) Infections / Tuberculosis1
2CompletedPreventionHerpes simplex of the genitals / Ulcers1
2CompletedPreventionHuman Immunodeficiency Virus (HIV) Infections1
2CompletedTreatmentCancer, Breast1
2CompletedTreatmentEpilepsies / Infantile Spasms (IS)1
2RecruitingPreventionVincristine Induced Peripheral Neuropathy (VIPN)1
2RecruitingTreatmentHIV Disease1
2RecruitingTreatmentHuman Immunodeficiency Virus (HIV) Infections1
2RecruitingTreatmentMultiple Myeloma (MM)1
2Unknown StatusTreatmentNodding Syndrome1
2WithdrawnTreatmentColorectal Cancers1
2WithdrawnTreatmentMalignant Lymphomas1
2WithdrawnTreatmentPlasma Cell Myeloma1
2, 3CompletedTreatmentAtherosclerosis1
2, 3CompletedTreatmentCardiovascular Disease (CVD) / Chronic Kidney Disease (CKD) / Mortality1
3CompletedPreventionCerebral Infarctions / Myocardial Infarction (MI) / Strokes1
3CompletedPreventionCerebrovascular Stroke / Coronary Artery Disease / Myocardial Infarction (MI)1
3CompletedPreventionComplications, Pregnancy / Human Immunodeficiency Virus (HIV) Infections1
3CompletedPreventionHand-foot Syndrome1
3CompletedPreventionHyperemesis Gravidarum / Pregnancy1
3CompletedSupportive CareCancer Related Fatigue / Quality of Life1
3CompletedTreatmentAlzheimer's Disease (AD)1
3CompletedTreatmentAnemias1
3CompletedTreatmentDiarrheal Illnesses / Growth Faltering / Respiratory Illness1
3CompletedTreatmentEndometrial Biopsy1
3CompletedTreatmentHuman Immunodeficiency Virus (HIV) Infections / Tuberculosis1
3CompletedTreatmentHuman Immunodeficiency Virus (HIV) Infections / Tuberculosis, Pulmonary1
3CompletedTreatmentHydatidiform Mole1
3CompletedTreatmentNausea and Vomiting of Pregnancy1
3Unknown StatusNot AvailableAnemias / Low Birth Weight / Neonatal Mortality1
3Unknown StatusTreatmentAlzheimer's Disease (AD) / Down Syndrome (DS)1
3WithdrawnPreventionTardive Dyskinesia1
4CompletedTreatmentAcute Schizophrenia1
4CompletedTreatmentDiabetic Peripheral Neuropathic Pain1
4CompletedTreatmentHyperemesis Gravidarum / Morning Sickness / Nausea / Pregnancy / Vomiting1
4CompletedTreatmentPregnancy1
4RecruitingTreatmentHuman Immunodeficiency Virus (HIV) Infections1
4RecruitingTreatmentLeiomyomas1
4RecruitingTreatmentMorning Sickness1
4Unknown StatusTreatmentNausea and Vomiting Complain in Early Pregnancy1
4WithdrawnTreatmentNephritis / Proteinuria / Systemic Lupus Erythematosus (SLE)1
Not AvailableCompletedNot AvailableHuman Immunodeficiency Virus (HIV) Infections1
Not AvailableCompletedPreventionHuman Immunodeficiency Virus (HIV) Infections / Tuberculosis1
Not AvailableCompletedPreventionNeural Tube Defects (NTDs)1
Not AvailableCompletedTreatmentAcute Myocardial Infarction (AMI)1
Not AvailableCompletedTreatmentEnd Stage Renal Disease (ESRD) / Hyperhomocysteinaemia1
Not AvailableCompletedTreatmentHuman Immunodeficiency Virus (HIV) Infections1
Not AvailableCompletedTreatmentHuman Immunodeficiency Virus (HIV) Infections / Tuberculosis4
Not AvailableNot Yet RecruitingTreatmentBreast Cancer Metastatic / Metastatic Breast Cancer (MBC)1
Not AvailableRecruitingTreatmentTemporomandibular Joint Disorders1
Not AvailableUnknown StatusPreventionHand and foot syndrome secondary to sickle cell anaemia1
Not AvailableUnknown StatusTreatmentAbnormal Uterine Bleeding Unrelated to Menstrual Cycle1
Not AvailableWithdrawnNot AvailablePyridoxine Dependant Epilepsy1
Not AvailableWithdrawnPreventionStrokes / Transient Ischaemic Attack (TIA)1
Pharmacoeconomics
Manufacturers
  • Eli lilly and co
  • Akorn inc
  • App pharmaceuticals llc
  • Bel mar laboratories inc
  • Dell laboratories inc
  • Elkins sinn div ah robins co inc
  • Luitpold pharmaceuticals inc
  • Watson laboratories inc
Packagers
Dosage forms
FormRouteStrength
Capsule; liquidOral
ElixirOral
Tablet, extended releaseOral500 mg
InjectionIntramuscular
Injection, solutionIntramuscular; Intravenous
Tablet, extended releaseOral400 mg
Powder, for solutionIntramuscular; Intravenous
Powder, for solutionIntravenous
WaferOral
TabletOral2 mg
CreamTopical
Kit
TabletOral
SprayTopical
Tablet, delayed releaseOral
Tablet, extended releaseOral
SyrupOral
TabletOral8.45 mg
LiquidIntramuscular; Intravenous
PowderOral
Tablet, chewableOral
TabletOral6 mg
TabletOral8.33 mg
TabletOral10 mg
LiquidIntravenous
Injection, powder, lyophilized, for solutionIntravenous
Liquid; tabletOral
Solution / dropsOral
SolutionIntravenous
LiquidOral
SolutionOral
Capsule, gelatin coatedOral
SolutionIntramuscular; Intravenous
CapsuleOral
Injection, solutionIntravenous
PasteDental
Tablet, coatedOral
LiquidIntramuscular; Intravenous100 mg
Injection, solutionIntramuscular; Intravenous100 mg/mL
SolutionIntramuscular; Intravenous100 mg
Tablet, effervescentOral
Powder, for solutionOral
KitOral
Capsule, extended releaseOral
Tablet, extended releaseOral100 mg
TabletOral50 mg
CapsuleOral250 mg
Capsule, liquid filledOral
InjectionIntramuscular; Intravenous
InjectionIntravenous
CapsuleOral100 mg
TabletOral17 mg
CapsuleOral200 mg
TabletOral200 mg
CapsuleOral3.5 mg
TabletOral250 mg
TabletOral100 mg
TabletOral25 mg
Tablet, film coatedOral
LozengeOral
Prices
Unit descriptionCostUnit
Pyridoxine HCl 100 50 mg tablet Bottle12.99USD bottle
Pyridoxine HCl 100 mg/ml vial11.69USD vial
Pyridoxine 100 mg/ml vial10.79USD ml
Pyridoxine hcl crystals6.94USD g
Pyridoxine 500 mg tablet0.18USD tablet
Pyridoxine 25 mg tablet0.14USD tablet
Neuro k 500 mg tablet0.13USD tablet
Pyridoxine 250 mg tablet0.13USD tablet
CVS Pharmacy vitamin b-6 200 mg tablet0.07USD tablet
Neuro-k 250 mg tablet0.06USD tablet
Pyridoxine 50 mg tablet0.06USD tablet
Vitamin b-6 100 mg tablet0.04USD tablet
CVS Pharmacy vitamin b-6 100 mg tablet0.03USD tablet
Pyridoxine 100 mg tablet0.03USD tablet
Vitamin b6 50 mg tablet0.03USD tablet
Vitamin b-6 50 mg tablet0.03USD tablet
CVS Pharmacy vitamin b-6 50 mg tablet0.02USD tablet
Vitamin b-6 25 mg tablet0.02USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US6340695 No2001-06-212021-06-21Us
US7560122 No1999-01-252019-01-25Us
US9526703 No2013-02-182033-02-18Us
US9375404 No2013-02-182033-02-18Us
US9089489 No2013-02-182033-02-18Us
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point (°C)159-162 °CPhysProp
water solubility2.2E+005 mg/LNot Available
logP-0.77SANGSTER (1993)
Predicted Properties
PropertyValueSource
Water Solubility16.1 mg/mLALOGPS
logP-0.57ALOGPS
logP-0.95ChemAxon
logS-1ALOGPS
pKa (Strongest Acidic)9.4ChemAxon
pKa (Strongest Basic)5.58ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area73.58 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity44.11 m3·mol-1ChemAxon
Polarizability17.11 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9728
Blood Brain Barrier+0.6889
Caco-2 permeable-0.8958
P-glycoprotein substrateNon-substrate0.5579
P-glycoprotein inhibitor INon-inhibitor0.9723
P-glycoprotein inhibitor IINon-inhibitor0.9221
Renal organic cation transporterNon-inhibitor0.8177
CYP450 2C9 substrateNon-substrate0.7386
CYP450 2D6 substrateNon-substrate0.781
CYP450 3A4 substrateNon-substrate0.7104
CYP450 1A2 substrateNon-inhibitor0.9046
CYP450 2C9 inhibitorNon-inhibitor0.9071
CYP450 2D6 inhibitorNon-inhibitor0.923
CYP450 2C19 inhibitorNon-inhibitor0.9025
CYP450 3A4 inhibitorNon-inhibitor0.8648
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.695
Ames testNon AMES toxic0.9133
CarcinogenicityNon-carcinogens0.9418
BiodegradationNot ready biodegradable0.5678
Rat acute toxicity1.6573 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.8454
hERG inhibition (predictor II)Non-inhibitor0.8734
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Spectra
Mass Spec (NIST)Not Available
Spectra
Spectrum TypeDescriptionSplash Key
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)splash10-000t-0940000000-30b4702623a6d8fcb4bbView in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies)splash10-001j-0690000000-0581e2b42fa48c1ea498View in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)splash10-00di-9330000000-32929ff06762b9f5887fView in MoNA
GC-MSGC-MS Spectrum - GC-MS (3 TMS)splash10-001i-0490000000-34a09ddbbb462aeb02a6View in MoNA
Predicted GC-MSPredicted GC-MS Spectrum - GC-MSNot Available
GC-MSGC-MS Spectrum - EI-Bsplash10-0f6x-9400000000-486db54a30b61c2eb9d4View in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOFsplash10-001j-0790000000-6f8f6e679e03f9119a65View in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOFsplash10-001j-0790000000-6f8f6e679e03f9119a65View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-0vi0-0900000000-bd0de86c072765a5caadView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-001i-3900000000-2018b406a3c75213b733View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-0059-9200000000-e69bb531deb2a103a476View in MoNA
LC-MS/MSLC-MS/MS Spectrum - EI-B (HITACHI M-80) , Positivesplash10-0f6x-9400000000-77c43a946c4ae1abf3b9View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negativesplash10-014i-0900000000-479d4492cc8d634fa366View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negativesplash10-0udi-0900000000-486d6a4e5e1a731b7c54View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negativesplash10-05fr-0900000000-4ef09ce9c04561a1085eView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negativesplash10-0ab9-1900000000-3298adf6db36689d5d43View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negativesplash10-0a6r-7900000000-6711954ee96f08344434View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positivesplash10-00di-0900000000-234e90d43a7febd7a098View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positivesplash10-0udi-0900000000-137080765c0035b45258View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positivesplash10-001i-0900000000-882ee900a8bba08e2c7cView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positivesplash10-003r-8900000000-e0e11797b63cea991d81View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positivesplash10-0059-9100000000-c25384179219411af02cView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Positivesplash10-0ue9-0900000000-c0e149ce890192397b7fView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Negativesplash10-0v4i-0900000000-f9f378af3d47ab006806View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-TOF , negativesplash10-0uxr-0900000000-dd61975d762fdc6e1e95View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ , positivesplash10-003r-8900000000-ffea92733494372f905dView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ , positivesplash10-0059-9100000000-ef6ae8502e892d6053f0View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-0uk9-0900000000-eab5b3411261744df750View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-0ue9-0900000000-cc4dc8719602182ef1ebView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-001i-5900000000-1c2637733578fcdd7c6aView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-014i-0900000000-e89cc69d8b21012ff982View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-059i-0900000000-0ad8d09e042015cb2e33View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-0a4i-9500000000-577a3d87899ca47d539fView in MoNA
MSMass Spectrum (Electron Ionization)splash10-1003-6900000000-1237eaf82dfadfd54d4bView in MoNA
1D NMR1H NMR SpectrumNot Available
1D NMR1H NMR SpectrumNot Available
1D NMR13C NMR SpectrumNot Available
2D NMR[1H,1H] 2D NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as pyridoxines. These are pyridoxal derivatives in which the carbaldehyde group at position 2 of the pyridoxal moiety is replaced by a hydroxymethyl group.
KingdomOrganic compounds
Super ClassOrganoheterocyclic compounds
ClassPyridines and derivatives
Sub ClassPyridoxines
Direct ParentPyridoxines
Alternative ParentsMethylpyridines / Hydroxypyridines / Heteroaromatic compounds / Azacyclic compounds / Primary alcohols / Organopnictogen compounds / Organonitrogen compounds / Hydrocarbon derivatives / Aromatic alcohols
SubstituentsPyridoxine / Methylpyridine / Hydroxypyridine / Heteroaromatic compound / Azacycle / Organic nitrogen compound / Organic oxygen compound / Organopnictogen compound / Hydrocarbon derivative / Aromatic alcohol
Molecular FrameworkAromatic heteromonocyclic compounds
External Descriptorsmonohydroxypyridine, methylpyridines, vitamin B6, hydroxymethylpyridine (CHEBI:16709 ) / Water-soluble vitamins (C00314 ) / a vitamin B6 (PYRIDOXINE )

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
ligand
General Function:
Zinc ion binding
Specific Function:
Required for synthesis of pyridoxal-5-phosphate from vitamin B6.
Gene Name:
PDXK
Uniprot ID:
O00764
Uniprot Name:
Pyridoxal kinase
Molecular Weight:
35102.105 Da
References
  1. Adams JB, George F, Audhya T: Abnormally high plasma levels of vitamin B6 in children with autism not taking supplements compared to controls not taking supplements. J Altern Complement Med. 2006 Jan-Feb;12(1):59-63. [PubMed:16494569 ]
  2. Newman JA, Das SK, Sedelnikova SE, Rice DW: The crystal structure of an ADP complex of Bacillus subtilis pyridoxal kinase provides evidence for the parallel emergence of enzyme activity during evolution. J Mol Biol. 2006 Oct 20;363(2):520-30. Epub 2006 Aug 12. [PubMed:16978644 ]
  3. Kim SY, An JJ, Kim DW, Choi SH, Lee SH, Hwang SI, Kwon OS, Kang TC, Won MH, Cho SW, Park J, Eum WS, Lee KS, Choi SY: Tat-mediated protein transduction of human brain pyridoxine-5-P oxidase into PC12 cells. J Biochem Mol Biol. 2006 Jan 31;39(1):76-83. [PubMed:16466641 ]
  4. Nagahashi Y, Tazoe M, Hoshino T: Cloning of the pyridoxine 5'-phosphate phosphatase gene (pdxP) and vitamin B6 production in pdxP recombinant Sinorhizobium meliloti. Biosci Biotechnol Biochem. 2008 Feb;72(2):421-7. Epub 2008 Feb 7. [PubMed:18256491 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
no
Actions
inhibitor
General Function:
Vitamin d 24-hydroxylase activity
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Gene Name:
CYP1A1
Uniprot ID:
P04798
Uniprot Name:
Cytochrome P450 1A1
Molecular Weight:
58164.815 Da
References
  1. Tangjarukij C, Navasumrit P, Zelikoff JT, Ruchirawat M: The effects of pyridoxine deficiency and supplementation on hematological profiles, lymphocyte function, and hepatic cytochrome P450 in B6C3F1 mice. J Immunotoxicol. 2009 Sep;6(3):147-60. doi: 10.1080/15476910903083866. [PubMed:19637937 ]
Drug created on June 13, 2005 07:24 / Updated on August 08, 2017 11:02