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Displaying drugs 676 - 700 of 764 in total

Fondaparinux

Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Description: … Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and ... It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they ... The monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural …
Matched Salts name: … Fondaparinux sodium …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Fondaparinux Sodium ... FONDAPARINUX SODIUM ... Fondaparinux Sodium Injection …

Milrinone

Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in complex systemic pathologies. Heart...
Approved
Matched Description: … and peripheral vasodilation in acute decongested heart failure. ... failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and ... cyclic adenosine monophosphate (cAMP) production, which affects the heart's contractile function and …
Matched Mixtures name: … Milrinone Lactate in Dextrose …
Matched Products: … Milrinone Lactate in Dextrose …

Neoarsphenamine

Investigational
Withdrawn
Matched Synonyms: … Sodium p,p'-dihydroxy-m,m'-diaminoarsenobenzene-n-monomethanol sulfoxylate ... Sulfoxylic acid, mono(((5-((3-amino-4-hydroxyphenyl)diarsenyl)-2-hydroxyphenyl)amino)methyl) ester, sodium …
Matched Iupac: … sodium {[({5-[(1E)-2-(3-amino-4-hydroxyphenyl)diarsen-1-yl]-2-hydroxyphenyl}amino)methoxy]sulfanyl}olate …

Somatrogon

Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES …
Matched Description: … adolescence and regulating metabolic function in adulthood. ... of somatrogon and allows its once-weekly dosing. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Somatropin and Somatropin Agonists …

Morrhuic acid

Morrhuic acid is a mixture of unsaturated fatty acids obtained from cod liver oil.
Experimental
Matched Salts name: … Morrhuate sodium …
Matched Products: … Morrhuate Sodium …

Iopodic acid

Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6. Due to its particular structure, it presents a high degree of lipid solubility and a...
Approved
Investigational
Withdrawn
Matched Description: … It was developed and filed to the FDA by the company BRACCO. ... formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and ... [A32080] Due to its particular structure, it presents a high degree of lipid solubility and a radiopaque …
Matched Salts name: … Ipodate sodium ... Ipodate calcium …
Matched Categories: … sodium iopodate ... calcium iopodate …
Matched Products: … Oragrafin Sodium 0.5gm …

Phosphorus P-32

Phosphorus P-32 is a radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity. Emitted by phosphorus P32, beta particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular biological macromolecules, resulting in tumor cell death.
Experimental
Matched Description: … Emitted by phosphorus P32, beta particles directly damage cellular DNA and, by ionizing intracellular ... water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular …
Matched Products: … P32 Sodium Phosphate …

Brimonidine

Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Description: … Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in ... Early treatment and management of glaucoma, which predominantly involves the lowering of intraocular ... Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and …
Matched Mixtures name: … Brimonidine Tartrate and Timolol Maleate ... BRIMONIDINE TARTRATE and TIMOLOL MALEATE ... Brimonidine Tartrate and Timolol Maleate …
Matched Categories: … Decongestants and Antiallergics ... Antiglaucoma Preparations and Miotics ... Skin and Mucous Membrane Agents …
Matched Products: … Brimonidine Tartrate 0.25% / Potassium Azeloyl Diglycinate 8% …

Meclofenamic acid

A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Approved
Vet approved
Matched Description: … A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. …
Matched Salts name: … Meclofenamate sodium …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Meclofenamate Sodium …

Butyric Acid

A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
Experimental
Investigational
Matched Description: … A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the …
Matched Salts name: … Sodium butyrate …
Matched Products: … Sodium Butyrate …

Sulbenicillin

Experimental
Matched Salts name: … Sulbenicillin sodium …
Matched Products: … SULBENICILLIN SODIUM …

Chromium Cr-51

Chromium Cr-51 is an isotope of chromium that has been used as a radioactive label for decades. It is used as a diagnostic radiopharmaceutical agent in nephrology to determine glomerular filtration rate,[A249765,A249770] and in hematology to determine red blood cell volume or mass, study the red blood cell survival time...
Approved
Matched Description: … in hematology to determine red blood cell volume or mass, study the red blood cell survival time and ... diagnostic radiopharmaceutical agent in nephrology to determine glomerular filtration rate,[A249765,A249770] and …
Matched Salts name: … Chromium Cr-51 chloride …
Matched Products: … Sodium Chromate 51 …

Nafcillin

A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Salts name: … Nafcillin sodium …
Matched Products: … Nafcillin Sodium …

Patent Blue

Patent blue is aniline dye and it is one of the most common dyes used. It is a sodium or calcium salt of diethylammonium hydroxide inner salt. It has the chemical designation of (4-(alpha-(p-(diethylamino)phenyl)-2,4-disulfobenzylidene)-2,5-cyclohexadiene-1-ylidene)diethylammonium hydroxide. Patent blue was developed by Guerbet and approved by Health Canada on December 31, 1979....
Approved
Matched Description: … [A32573] It is a sodium or calcium salt of diethylammonium hydroxide inner salt. ... Patent blue is aniline dye and it is one of the most common dyes used. ... Patent blue was developed by Guerbet and approved by Health Canada on December 31, 1979. …
Matched Salts name: … Patent Blue V calcium ... Patent Blue V sodium …
Matched Products: … Patent Blue Sodium Injection …

Carbazochrome sulfonic acid

Experimental
Matched Salts name: … Carbazochrome sodium sulfonate …
Matched Products: … CARBAZOCHROME SODIUM SULFONATE …

Beraprost

Beraprost is a synthetic analogue of prostacyclin, under clinical trials for the treatment of pulmonary hypertension. It is also being studied for use in avoiding reperfusion injury.
Investigational
Matched Salts name: … Beraprost sodium …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … BERAPROST SODIUM …

Cilastatin

Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Mixtures name: … IMIPENEM MONOHYDRATE - CILASTATIN SODIUM ... IMIPENEM MONOHYDRATE / CILASTATIN SODIUM ... IMIPEMEM CILASTATINA SODICA …
Matched Salts name: … Cilastatin sodium …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Matched Products: … Cilastatin Sodium Sterile …

Silicon dioxide

Silicon dioxide, or silica, is an oxide of silicon with the chemical formula SiO2. It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite as transparent and tasteless crystals. Inhalation of fine crystals is toxic to humans leading to respiratory toxicity. In powdered food products...
Approved
Matched Description: … as transparent and tasteless crystals. ... Colloidal silica is also used as a wine, beer, and juice fining agent or stabilizer. ... It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite …
Matched Mixtures name: … Calcium and Magnesium 1:1 Plus Tablets ... Men's Biomultiple Vitamin and Mineral Supplement ... Women's Biomultiple Vitamin and Mineral Supplement …
Matched Products: … Chlorine Dioxide Air Sterilization Card …

Fosinopril

Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and...
Approved
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and ... to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and …
Matched Mixtures name: … Fosinopril Sodium and Hydrochlorothiazide ... Fosinopril Sodium and Hydrochlorothiazide ... Fosinopril Sodium and Hydrochlorothiazide …
Matched Salts name: … Fosinopril sodium …
Matched Categories: … ACE Inhibitors and Diuretics ... fosinopril and diuretics ... Amino Acids, Peptides, and Proteins …
Matched Products: … Fosinopril Sodium ... Fosinopril sodium …

Methylprednisolone hemisuccinate

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Approved
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Matched Salts name: … Methylprednisolone sodium succinate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Methylprednisolone Sodium Succinate ... METHYLPREDNISOLONE SODIUM SUCCINATE ... Methylprednisolone sodium succinate …

Phenylbutyric acid

Phenylbutyric acid is a fatty acid and a derivative of butyric acid naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Approved
Investigational
Matched Description: … It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Salts name: … Sodium phenylbutyrate …
Matched Categories: … Alimentary Tract and Metabolism ... sodium phenylbutyrate ... Various Alimentary Tract and Metabolism Products …
Matched Products: … Sodium Phenylbutyrate …

Nedocromil

A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.
Approved
Investigational
Matched Description: … are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and …
Matched Salts name: … Nedocromil sodium …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Nedocromil Sodium …

Docetaxel

Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …

Dextrorphan

Experimental
Matched Synonyms: … Dextro-dromoran …

Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol)

Approved
Matched Synonyms: … 1,2-dipalmitoyl-sn-glycero-3-phosphorylglycerol sodium salt …
Matched Name: … Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) …
Matched Iupac: … sodium (2R)-1-[(2,3-dihydroxypropyl phosphono)oxy]-3-(hexadecanoyloxy)propan-2-yl hexadecanoate …
Displaying drugs 676 - 700 of 764 in total