Displaying drugs 76 - 100 of 14990 in total
Chymotrypsin
Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Like most proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence...
Approved
Vet approved
Matched Synonyms: … Chymotrypsin A …
Matched Description: … It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. ... the most abundant pancreatic proteases that represent up to 10-20% of the total protein synthesized by ... Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins …
Matched Description: … It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. ... the most abundant pancreatic proteases that represent up to 10-20% of the total protein synthesized by ... Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins …
Haloperidol
Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Synonyms: … 4'-fluoro-4-(4-hydroxy-4-(4'-chlorophenyl)piperidino)butyrophenone ... 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one ... 4-(4-(para-chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone …
Matched Iupac: … 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one …
Matched Description: … an over-production of dopamine, such as schizophrenia, which is theorized to be caused by a hyperdopaminergic ... [A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain ... or histaminergic receptors, resulting in a higher incidence of side effects such as sedation, weight …
Matched Products: … HALOPERIDOL-NEURAX 4 MG ... MYUNG IN HALOPERIDOL TABLET 1.5 mg ... MYUNG IN HALOPERIDOL INJECTION 5 mg/ml …
Matched Iupac: … 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one …
Matched Description: … an over-production of dopamine, such as schizophrenia, which is theorized to be caused by a hyperdopaminergic ... [A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain ... or histaminergic receptors, resulting in a higher incidence of side effects such as sedation, weight …
Matched Products: … HALOPERIDOL-NEURAX 4 MG ... MYUNG IN HALOPERIDOL TABLET 1.5 mg ... MYUNG IN HALOPERIDOL INJECTION 5 mg/ml …
Oxybuprocaine
Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Synonyms: … 4-Amino-3-butoxy-2-(diethylamino)ethyl ester benzoic acid ... 4-Amino-3-n-butoxy-benzoesäure-diäthylaminoäthylester ... 4-Amino-3-butoxy-benzoic acid 2-diethylamino-ethyl ester …
Matched Iupac: … 2-(diethylamino)ethyl 4-amino-3-butoxybenzoate …
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology …
Matched Products: … Novain 4 mg/ml Augentropfen, Lösung ... Benoxinat 1% - Lösung zur Anästhesie in der Oto-Rhino-Laryngologie …
Matched Iupac: … 2-(diethylamino)ethyl 4-amino-3-butoxybenzoate …
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology …
Matched Products: … Novain 4 mg/ml Augentropfen, Lösung ... Benoxinat 1% - Lösung zur Anästhesie in der Oto-Rhino-Laryngologie …
Flurbiprofen
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Synonyms: … 3-fluoro-4-phenylhydratropic acid ... 2-(2-fluorobiphenyl-4-yl)propanoic acid ... (±)-2-fluoro-α-methyl-4-biphenylacetic acid …
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Description: … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic …
Matched Products: … NEO BOROCILLINA GOLA DOLORE ... STREPSILS INTENSIVE SOLUCION EN SPRAY SABOR A MIEL Y LIMON ... Strepsils 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung …
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Description: … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic …
Matched Products: … NEO BOROCILLINA GOLA DOLORE ... STREPSILS INTENSIVE SOLUCION EN SPRAY SABOR A MIEL Y LIMON ... Strepsils 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung …
Agalsidase alfa
Agalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Matched Synonyms: … alpha-galactosidase A ... Recombinant alpha-galactosidase A …
Matched Description: … a contamination event in 2009. ... While patients generally do not experience a clinically significant difference in outcomes between the ... Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta]. …
Matched Description: … a contamination event in 2009. ... While patients generally do not experience a clinically significant difference in outcomes between the ... Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta]. …
Estazolam
A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Approved
Illicit
Matched Synonyms: … 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Description: … A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. ... It has been shown in some cases to be more potent than diazepam or nitrazepam. …
Matched Description: … A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. ... It has been shown in some cases to be more potent than diazepam or nitrazepam. …
Alprazolam
Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms. Alprazolam's adverse...
Approved
Illicit
Investigational
Matched Synonyms: … 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Description: … [L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose ... [L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ... Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. …
Matched Description: … [L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose ... [L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ... Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. …
Collagenase clostridium histolyticum
Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease. The topical formulation is used for the debridement of necrotic tissue due to burns or chronic ulcers. On July 6,...
Approved
Investigational
Matched Synonyms: … Clostridiopeptidase A …
Matched Description: … [L14912] On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA ... for the treatment of cellulite in adult women. ... It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and …
Matched Description: … [L14912] On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA ... for the treatment of cellulite in adult women. ... It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and …
Nortriptyline
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Synonyms: … 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine ... 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine …
Matched Description: … Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Lyme disease vaccine (recombinant OspA)
Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as...
Approved
Withdrawn
Matched Synonyms: … Lipoprotein outer surface a borrelia burgdorferi antigen …
Matched Description: … lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by ... Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the …
Matched Description: … lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by ... Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the …
Exenatide
Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Synonyms: … Exendin 4 ... Exendin-4 ... Synthetic exendin-4 …
Matched Description: … Exenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690]. ... , was discontinued in 2021. ... [L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …
Matched Description: … Exenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690]. ... , was discontinued in 2021. ... [L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …
Norepinephrine
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Synonyms: … (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol ... 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol …
Matched Iupac: … 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol …
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in …
Matched Products: … Norepinephrine Bitartrate In Sodium Chloride ... Norepinephrine Bitartrate In 5% Dextrose Injection ... ADRENOR 4 MG/4 ML IV İNFÜZYONLUK ÇÖZELTİ …
Matched Iupac: … 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol …
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in …
Matched Products: … Norepinephrine Bitartrate In Sodium Chloride ... Norepinephrine Bitartrate In 5% Dextrose Injection ... ADRENOR 4 MG/4 ML IV İNFÜZYONLUK ÇÖZELTİ …
Chlorhexidine
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Synonyms: … N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide …
Matched Iupac: … N-(4-chlorophenyl)-1-{N'-[6-(N-{[N'-(4-chlorophenyl)carbamimidamido]methanimidoyl}amino)hexyl]carbamimidamido …
Matched Description: … [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two ... biguanide groups joined by a central hexamethylene chain. ... [L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the …
Matched Mixtures name: … easyangin Spray zur Anwendung in der Mundhöhle ... Cathejell Diphenhydramin 1 % / Chlorhexidin 0,05 % - Gel (in Tuben) ... Stanhexidine 4% With Isopropyl Alcohol 4% …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Alsoft A Hand Disinfectant 0.2% w/v ... Chlorhexamed 1% - Gel zur Anwendung in der Mundhöhle ... Chlorhexamed Direkt 1 % - Gel zur Anwendung in der Mundhöhle …
Matched Iupac: … N-(4-chlorophenyl)-1-{N'-[6-(N-{[N'-(4-chlorophenyl)carbamimidamido]methanimidoyl}amino)hexyl]carbamimidamido …
Matched Description: … [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two ... biguanide groups joined by a central hexamethylene chain. ... [L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the …
Matched Mixtures name: … easyangin Spray zur Anwendung in der Mundhöhle ... Cathejell Diphenhydramin 1 % / Chlorhexidin 0,05 % - Gel (in Tuben) ... Stanhexidine 4% With Isopropyl Alcohol 4% …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Alsoft A Hand Disinfectant 0.2% w/v ... Chlorhexamed 1% - Gel zur Anwendung in der Mundhöhle ... Chlorhexamed Direkt 1 % - Gel zur Anwendung in der Mundhöhle …
Lixisenatide
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Synonyms: … DesPro38Exendin-4(1-39)-Lys6-NH2 ... des-38-proline-exendine-4 (Heloderma suspectum)-(1-39)-peptidylpenta-L-lysyl-L-lysinamide …
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. ... Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes …
Matched Mixtures name: … Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 33MCG/ML …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG (50mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MCG (100mcg/mL) …
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. ... Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes …
Matched Mixtures name: … Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 33MCG/ML …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG (50mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MCG (100mcg/mL) …
Progesterone
Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Matched Synonyms: … (S)-4-Pregnene-3,20-dione ... 4-Pregnene-3,20-dione ... (S)-Pregn-4-en-3,20-dione …
Matched Iupac: … ,9bS,11aS)-1-acetyl-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity ... Pharmaceutical progesterone is made from a plant source as a starting material and is chemically identical ... ], [A175612] as well as in other formulations to promote and support pregnancy. …
Matched Products: … N/A ... Gesterol In Oil-liq Im 50mg/ml ... Progedex 25 mg Injektionslösung in einer Fertigspritze …
Matched Iupac: … ,9bS,11aS)-1-acetyl-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity ... Pharmaceutical progesterone is made from a plant source as a starting material and is chemically identical ... ], [A175612] as well as in other formulations to promote and support pregnancy. …
Matched Products: … N/A ... Gesterol In Oil-liq Im 50mg/ml ... Progedex 25 mg Injektionslösung in einer Fertigspritze …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A ... -D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-(4-AMINO-2-HYDROXY-1-OXOBUTYL)-2-DEOXY-, (S)- ... -D-GLUCOPYRANOSYL-(1->4)-O-(6-AMINO-6-DEOXY-.ALPHA. …
Matched Iupac: … (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl) ... oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl …
Matched Description: … [F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for ... the treatment of lung disease caused by Mycobacterium avium complex (MAC) bacteria in a small population ... M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … AMIKACINA 1G/4 ML ... RYOFEL 1000 MG/4 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... RYOFEL 1000 MG/4 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ, 10 ADET …
Matched Iupac: … (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl) ... oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl …
Matched Description: … [F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for ... the treatment of lung disease caused by Mycobacterium avium complex (MAC) bacteria in a small population ... M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … AMIKACINA 1G/4 ML ... RYOFEL 1000 MG/4 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... RYOFEL 1000 MG/4 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ, 10 ADET …
Fentanyl
Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone.
Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … 1-phenethyl-4-N-propionylanilinopiperidine ... 1-Phenethyl-4-(N-phenylpropionamido)piperidine ... N-(1-phenethyl-4-piperidyl)propionanilide …
Matched Iupac: … N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide …
Matched Description: … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia ... Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin. ... [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose …
Matched Products: … DUROGESIC SMAT 12 A 2.1MG ... DUROGESIC SMAT 25 A 4.2MG ... DUROGESIC SMAT 50 A 8.4MG …
Matched Iupac: … N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide …
Matched Description: … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia ... Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin. ... [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose …
Matched Products: … DUROGESIC SMAT 12 A 2.1MG ... DUROGESIC SMAT 25 A 4.2MG ... DUROGESIC SMAT 50 A 8.4MG …
Mianserin
A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Approved
Investigational
Matched Synonyms: … 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine …
Matched Description: … A tetracyclic compound with antidepressant effects. ... Mianserin was previously available internationally, however in most markets it has been phased out in …
Matched Description: … A tetracyclic compound with antidepressant effects. ... Mianserin was previously available internationally, however in most markets it has been phased out in …
Torasemide
Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Synonyms: … 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea ... N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Description: … [A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257] ... Torasemide is a high-ceiling loop diuretic. ... [A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. …
Matched Products: … SUTRIL NEO 10 MG UZATILMIŞ SALIMLI TABLET,15 ADET ... SUTRIL NEO 5 MG UZATILMIŞ SALIMLI TABLET,15 ADET ... SUTRIL NEO 5 MG UZATILMIŞ SALIMLI TABLET,30 ADET …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Description: … [A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257] ... Torasemide is a high-ceiling loop diuretic. ... [A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. …
Matched Products: … SUTRIL NEO 10 MG UZATILMIŞ SALIMLI TABLET,15 ADET ... SUTRIL NEO 5 MG UZATILMIŞ SALIMLI TABLET,15 ADET ... SUTRIL NEO 5 MG UZATILMIŞ SALIMLI TABLET,30 ADET …
Acetyldigitoxin
Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Approved
Matched Synonyms: … Desglucolanatoside A …
Matched Iupac: … 9aS,9bS,11aR)-3a-hydroxy-9a,11a-dimethyl-1-(5-oxo-2,5-dihydrofuran-3-yl)-hexadecahydro-1H-cyclopenta[a] ... -4-yl acetate ... phenanthren-7-yl]oxy}-4-hydroxy-2-methyloxan-3-yl]oxy}-4-hydroxy-2-methyloxan-3-yl]oxy}-3-hydroxy-2-methyloxan …
Matched Description: … Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … 9aS,9bS,11aR)-3a-hydroxy-9a,11a-dimethyl-1-(5-oxo-2,5-dihydrofuran-3-yl)-hexadecahydro-1H-cyclopenta[a] ... -4-yl acetate ... phenanthren-7-yl]oxy}-4-hydroxy-2-methyloxan-3-yl]oxy}-4-hydroxy-2-methyloxan-3-yl]oxy}-3-hydroxy-2-methyloxan …
Matched Description: … Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Iptacopan
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … is of particular importance to PNH, where one of the disease hallmarks is the mutation of the PIGA gene ... Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for ... the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … is of particular importance to PNH, where one of the disease hallmarks is the mutation of the PIGA gene ... Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for ... the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor …
Desoxyribonuclease
Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into fragments approaching the size of tetranucleotides without the release of free phosphoric acid. The enzyme's cofactor is reported to be...
Approved
Matched Synonyms: … Deoxyribonuclease A …
Matched Description: … Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. …
Matched Description: … Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. …
Rezafungin
Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week...
Approved
Investigational
Matched Synonyms: … Echinocandin B, 1-((4R,5R)-4-hydroxy-N2-((4''-(pentyloxy)(1,1':4',1''-terphenyl)-4-yl)carbonyl)-5-(2- ... (trimethylammonio)ethoxy)-l-ornithine)-4-((4S)-4-hydroxy-4-(4-hydroxyphenyl)-l-allothreonine)- …
Matched Iupac: … )ethyl]-5,8,11,17,20,23,25-heptahydroxy-18-[(Z)-[hydroxy({4-[4'-(pentyloxy)-[1,1'-biphenyl]-4-yl]phenyl ... (2-{[(3S,4E,6S,7E,9S,11R,15S,16E,18S,20R,21R,22E,24S,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl …
Matched Description: … Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily ... invasive candidiasis in adults with limited or no alternative treatment options. ... echinocandins such as [caspofungin] and [micafungin], rezafungin has long‐acting pharmacokinetics and a …
Matched Iupac: … )ethyl]-5,8,11,17,20,23,25-heptahydroxy-18-[(Z)-[hydroxy({4-[4'-(pentyloxy)-[1,1'-biphenyl]-4-yl]phenyl ... (2-{[(3S,4E,6S,7E,9S,11R,15S,16E,18S,20R,21R,22E,24S,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl …
Matched Description: … Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily ... invasive candidiasis in adults with limited or no alternative treatment options. ... echinocandins such as [caspofungin] and [micafungin], rezafungin has long‐acting pharmacokinetics and a …
Dalfampridine
Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
Approved
Matched Synonyms: … 4-AP ... 4-Aminopyridine ... 4-Pyridinamine …
Matched Iupac: … 1,4-dihydropyridin-4-imine …
Matched Description: … Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. ... This is the first drug that was specifically approved to help with mobility in these patients. …
Matched Categories: … OCT2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 1,4-dihydropyridin-4-imine …
Matched Description: … Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. ... This is the first drug that was specifically approved to help with mobility in these patients. …
Matched Categories: … OCT2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Hydrocortisone
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched Synonyms: … 4-pregnen-11β,17α,21-triol-3,20-dione ... (11β)-11,17,21-trihydroxypregn-4-ene-3,20-dione ... 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione …
Matched Iupac: … 1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. ... [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named …
Matched Mixtures name: … Cho-A Care Lot 1% ... Neo-poly-bac Hydro ... NEO-HYTISONE CREAM …
Matched Products: … Hydrocortisone 1% in Absorbase ... SKIN A COOL Hydrocortisone Anti-Itch …
Matched Iupac: … 1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. ... [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named …
Matched Mixtures name: … Cho-A Care Lot 1% ... Neo-poly-bac Hydro ... NEO-HYTISONE CREAM …
Matched Products: … Hydrocortisone 1% in Absorbase ... SKIN A COOL Hydrocortisone Anti-Itch …
Displaying drugs 76 - 100 of 14990 in total