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Displaying drugs 101 - 125 of 288 in total
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Synonyms: … Lisinopril anhydrous
Methylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered...
Approved
Investigational
Matched Synonyms: … Methylene blue anhydrous
An ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Approved
Matched Salts name: … Ergonovine maleate
Matched Products: … Ergotrate Maleate ... Ergonovine Maleate ... Ergonovine Maleate Injection …
A cephalorsporin antibiotic that is no longer commonly used.
Approved
Matched Synonyms: … Cephaloglycin anhydrous
The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease...
Approved
Illicit
Matched Synonyms: … Codeine anhydrous
Matched Mixtures name: … Codeine and Chlorpheniramine Maleate ER …
Matched Salts name: … Codeine sulfate anhydrous
Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Approved
Matched Mixtures name: … Brompheniramine maleate, pseudoephedrine hydrochloride, ... Brompheniramine maleate, pseudoephedrine hydrochloride, ... Brompheniramine Maleate, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide …
Matched Salts name: … Brompheniramine maleate
Matched Products: … Brompheniramine Maleate ... BROMPHENIRAMINE MALEATE TABLETS …
A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Mixtures name: … Phenylephrine Hydrochloride, Chlorpheniramine Maleate ... Codeine and Chlorpheniramine Maleate ER ... Hydrocodone Bitartrate and Chlorpheniramine Maleate
Matched Salts name: … Chlorpheniramine maleate
Matched Products: … Chlorpheniramine Maleate ... Chlorpheniramine maleate ... CHLORPHENAMINE MALEATE
Beclomethasone dipropionate is a second-generation synthetic corticosteroid and diester of beclomethasone, which is structurally similar to dexamethasone. It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) which acts on the glucocorticoid receptor to mediates its therapeutic action. Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is...
Approved
Investigational
Matched Synonyms: … Beclometasone dipropionate anhydrous
Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor...
Approved
Investigational
Matched Salts name: … Rosiglitazone Maleate
Matched Products: … Rosiglitazone Maleate
Developed by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine also belongs to the dibenzo-oxepino pyrrole class. It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use....
Approved
Matched Salts name: … Asenapine maleate
Matched Products: … Asenapine Maleate
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … Levofloxacin anhydrous
Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Products: … Terazosin Hydrochloride Anhydrous
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Mixtures name: … Brompheniramine Maleate Pseudoephedrine HCl ... Brompheniramine maleate, pseudoephedrine hydrochloride, ... Brompheniramine maleate, pseudoephedrine hydrochloride, …
Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Mixtures name: … Naphazoline HCI And Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate
Pheniramine is a first-generation antihistamine in the alkylamine class, similar to brompheniramine and chlorpheniramine. It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs. Pheniramine's use as an anti-allergy medication has largely been supplanted by second-generation antihistamines such as cetirizine and...
Approved
Matched Mixtures name: … Naphazoline HCI And Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate
Matched Salts name: … Pheniramine maleate
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Salts name: … Amlodipine maleate
Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Approved
Matched Mixtures name: … Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid …
Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI...
Approved
Matched Description: … to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate
Matched Salts name: … Trimebutine maleate
Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Matched Description: … The anhydrous form of the compound also has water-absorbing properties. …
Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Salts name: … Tegaserod maleate
A long-acting beta-2-adrenergic receptor agonist. It is a potent bronchodilator that may be administered orally or by aerosol inhalation.
Approved
Investigational
Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Mixtures name: … Brompheniramine maleate, pseudoephedrine hydrochloride, ... Brompheniramine maleate, pseudoephedrine hydrochloride, ... Brompheniramine Maleate, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide …
Copper-64 is a radiopharmaceutical usually found in the +2 oxidation state as the complexes including the +1 state tend to be more unstable. It is used in molecular radiotherapy and positron emission tomography.
Approved
Matched Salts name: … Cupric chloride anhydrous Cu-64 …
A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
Approved
Investigational
Matched Salts name: … Methotrimeprazine maleate
Displaying drugs 101 - 125 of 288 in total