Displaying drugs 151 - 175 of 6213 in total
Eslicarbazepine acetate
Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. Eslicarbazepine acetate is a prodrug that is rapidly converted to eslicarbazepine, the primary active metabolite in the body....
Approved
Matched Synonyms: … (10S)-10-acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide ... (10S)-5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate …
Matched Iupac: … (9S)-2-carbamoyl-2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-9-yl acetate …
Matched Description: … Eslicarbazepine acetate is a prodrug that is rapidly converted to eslicarbazepine, the primary active ... that it does exert anticonvulsant activity by inhibiting repeated neuronal firing and stabilizing the inactivated …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … (9S)-2-carbamoyl-2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-9-yl acetate …
Matched Description: … Eslicarbazepine acetate is a prodrug that is rapidly converted to eslicarbazepine, the primary active ... that it does exert anticonvulsant activity by inhibiting repeated neuronal firing and stabilizing the inactivated …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Zileuton
Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and eosinophil migration, neutrophil and monocyte aggregation, leukocyte adhesion, increased capillary permeability, and smooth muscle contraction. These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients. Zileuton relieves such symptoms through its...
Approved
Investigational
Withdrawn
Matched Synonyms: … N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea ... N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea ... (±)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea …
Matched Iupac: … 1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea …
Matched Iupac: … 1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea …
Hydrocortisone butyrate
Approved
Vet approved
Matched Synonyms: … H-17-B …
Matched Iupac: … ,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl butanoate ... (1R,3aS,3bS,9aR,9bS,10S,11aS)-10-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H …
Matched Categories: … 11-Hydroxycorticosteroids …
Matched Products: … Aquax-H ... LULSADERM-H …
Matched Iupac: … ,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl butanoate ... (1R,3aS,3bS,9aR,9bS,10S,11aS)-10-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H …
Matched Categories: … 11-Hydroxycorticosteroids …
Matched Products: … Aquax-H ... LULSADERM-H …
Pheneticillin
Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally.
Approved
Matched Synonyms: … penicillin B …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxypropanamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Description: … Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxypropanamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Description: … Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally …
Pyruvic acid
An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … a-Ketopropionic acid ... 2-Oxopropansäure ... 2-Oxopropionsäure …
Matched Iupac: … 2-oxopropanoic acid …
Matched Iupac: … 2-oxopropanoic acid …
Coagulation Factor IX Human
Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Approved
Matched Synonyms: … Antihemophilic factor B …
Matched Description: … Deficiency of this protein causes hemophilia B. …
Matched Mixtures name: … PROTROMPLEX TIM 3 ... PROTROMPLEX TIM 3 ... COFACT 250 IU/10 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET …
Matched Products: … HAEMONİNE 1000 IU/10 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON + 1 ÇÖZÜCÜ FLAKON ... HAEMONİNE 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON + 1 ÇÖZÜCÜ FLAKON ... OCTANİNE F 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON+1 ÇÖZÜCÜ FLAKON …
Matched Description: … Deficiency of this protein causes hemophilia B. …
Matched Mixtures name: … PROTROMPLEX TIM 3 ... PROTROMPLEX TIM 3 ... COFACT 250 IU/10 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET …
Matched Products: … HAEMONİNE 1000 IU/10 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON + 1 ÇÖZÜCÜ FLAKON ... HAEMONİNE 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON + 1 ÇÖZÜCÜ FLAKON ... OCTANİNE F 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON+1 ÇÖZÜCÜ FLAKON …
Ibuprofen
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched International brands: … Act-3 …
Matched Synonyms: … (±)-2-(p-isobutylphenyl)propionic acid ... 2-(4-isobutylphenyl)propanoic acid ... (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid …
Matched Iupac: … 2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... was in 1960 while researching for a safer alternative for aspirin. ... [A39076] On the available products, ibuprofen is administered as a racemic mixture. …
Matched Mixtures name: … Adventure Medical Kits 1-2 Person First Aid ... Adventure Medical Kits 1-2 Person National Ski Patrol First Aid ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Categories: … COX-1 Inhibitors ... COX-2 Inhibitors ... Non COX-2 selective NSAIDS …
Matched Products: … PADUCAS 20 MG/2 ML I.V. İNFÜZYONLUK ÇÖZELTİ, 3 ADET ... DUKTAFEN 20 MG/2 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ, 3 ADET ... DISMENOL N …
Matched Synonyms: … (±)-2-(p-isobutylphenyl)propionic acid ... 2-(4-isobutylphenyl)propanoic acid ... (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid …
Matched Iupac: … 2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... was in 1960 while researching for a safer alternative for aspirin. ... [A39076] On the available products, ibuprofen is administered as a racemic mixture. …
Matched Mixtures name: … Adventure Medical Kits 1-2 Person First Aid ... Adventure Medical Kits 1-2 Person National Ski Patrol First Aid ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Categories: … COX-1 Inhibitors ... COX-2 Inhibitors ... Non COX-2 selective NSAIDS …
Matched Products: … PADUCAS 20 MG/2 ML I.V. İNFÜZYONLUK ÇÖZELTİ, 3 ADET ... DUKTAFEN 20 MG/2 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ, 3 ADET ... DISMENOL N …
Acetylsalicylic acid
Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction...
Approved
Vet approved
Matched Synonyms: … 2-Acetoxybenzoic acid ... 2-Acetoxybenzenecarboxylic acid ... acide 2-(acétyloxy)benzoïque …
Matched Iupac: … 2-(acetyloxy)benzoic acid …
Matched Description: … Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain ... Acetylsalicylic acid is a very common cause of accidental poisoning in young children. ... Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available …
Matched Salts cas: … 62952-06-1 …
Matched Mixtures name: … Fiorinal-C 1/2 ... Robaxisal C 1/2 ... Methoxisal-C 1/2 …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … ASPIRIN N 100MG ... ASPIRIN N 300MG …
Matched Iupac: … 2-(acetyloxy)benzoic acid …
Matched Description: … Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain ... Acetylsalicylic acid is a very common cause of accidental poisoning in young children. ... Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available …
Matched Salts cas: … 62952-06-1 …
Matched Mixtures name: … Fiorinal-C 1/2 ... Robaxisal C 1/2 ... Methoxisal-C 1/2 …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … ASPIRIN N 100MG ... ASPIRIN N 300MG …
VidPrevtyn Beta
VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline (GSK) and Sanofi Pasteur. It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant DNA technology using a baculovirus expression system in an insect cell line that is
derived from Sf9 cells of the fall...
Approved
Investigational
Matched Synonyms: … SARS-CoV-2 prefusion Spike delta TM protein, recombinant (B.1.351 strain) …
Matched Description: … [L49691] It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant ... booster dose in patients who have previously received a COVID-19 vaccine. ... DNA technology using a baculovirus expression system in an insect cell line that is derived from Sf9 …
Matched Description: … [L49691] It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant ... booster dose in patients who have previously received a COVID-19 vaccine. ... DNA technology using a baculovirus expression system in an insect cell line that is derived from Sf9 …
Pseudoephedrine
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Synonyms: … (+) threo-2-(methylamino)-1-phenyl-1-propanol ... d-psi-2-Methylamino-1-phenyl-1-propanol …
Matched Iupac: … (1S,2S)-2-(methylamino)-1-phenylpropan-1-ol …
Matched Description: … Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic ... [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional …
Matched Mixtures name: … RESTAFED - H ... Calmylin #3 Syr ... Z-cof 1 …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Iupac: … (1S,2S)-2-(methylamino)-1-phenylpropan-1-ol …
Matched Description: … Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic ... [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional …
Matched Mixtures name: … RESTAFED - H ... Calmylin #3 Syr ... Z-cof 1 …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Interferon gamma-1b
Human Interferon gamma-1b (140 residues), produced from E. coli. Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. Purification of the product is achieved by conventional column chromatography.
The sequence displayed is a cDNA sequence which...
Approved
Investigational
Matched Synonyms: … Interferon gamma 1-b …
Matched Description: … Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium ... The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray …
Matched Description: … Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium ... The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray …
Omacetaxine mepesuccinate
Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies. Omacetaxine mepesuccinate is synthesized from cephalotaxine, which is an extract from the leaves of the plant, Cephalotaxus species. In October 2005, omacetaxine mepesuccinate...
Approved
Investigational
Matched Synonyms: … 1-[(1S,3aR,14bS)-2-Methoxy-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-H]pyrrolo[2,1-b][ ... 3]benzazepin-1-yl] 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate ... CEPHALOTAXINE 4-METHYL (2R)-2-HYDROXY-2-(4-HYDROXY-4-METHYLPENTYL)BUTANEDIOATE (ESTER) …
Matched Iupac: … (19)-tetraen-3-yl 1-methyl (3R)-3-hydroxy-3-(4-hydroxy-4-methylpentyl)butanedioate ... (2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^{2,6}.0^{6,10}.0^{15,19}]icosa-1(20),4,13,15 …
Matched Description: … Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and ... protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies …
Matched Salts cas: … 457895-79-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (19)-tetraen-3-yl 1-methyl (3R)-3-hydroxy-3-(4-hydroxy-4-methylpentyl)butanedioate ... (2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^{2,6}.0^{6,10}.0^{15,19}]icosa-1(20),4,13,15 …
Matched Description: … Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and ... protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies …
Matched Salts cas: … 457895-79-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Chlorpheniramine
A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Synonyms: … 1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine ... 1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane ... 3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine …
Matched Iupac: … [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Description: … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. …
Matched Salts cas: … 25387-68-2 …
Matched Mixtures name: … N KOUT ... DAYFLU B ... Bio-B Kids …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ALERFIN 2 MG/5 ML ORAL ÇÖZELTI, 1 ŞIŞE ... คลอเฟน 2 ... AXCEL CHLORPHENIRAMINE-2 SYRUP …
Matched Iupac: … [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Description: … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. …
Matched Salts cas: … 25387-68-2 …
Matched Mixtures name: … N KOUT ... DAYFLU B ... Bio-B Kids …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ALERFIN 2 MG/5 ML ORAL ÇÖZELTI, 1 ŞIŞE ... คลอเฟน 2 ... AXCEL CHLORPHENIRAMINE-2 SYRUP …
Clomipramine
Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals,...
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine ... 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine ... 3-Chloroimipramine …
Matched Iupac: … (3-{14-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant ... See toxicity section below for a complete listing of side effects. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … (3-{14-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant ... See toxicity section below for a complete listing of side effects. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Entecavir
Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS).
Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents...
Approved
Investigational
Matched Iupac: … 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-6,9-dihydro-3H-purin-6-one …
Matched Description: … Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the ... Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. ... manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine …
Matched Categories: … Hepatitis B virus ... Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 2-Ring …
Matched Products: … HEPATOVIR-B 1 MG FILM KAPLI TABLET, 30 ADET ... HEPATOVIR-B 0.05 MG/ML ORAL ÇÖZELTİ, 210 ML ... HEPATOVIR-B 0.5 MG FILM KAPLI TABLET, TABLET, 30 ADET …
Matched Description: … Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the ... Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. ... manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine …
Matched Categories: … Hepatitis B virus ... Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 2-Ring …
Matched Products: … HEPATOVIR-B 1 MG FILM KAPLI TABLET, 30 ADET ... HEPATOVIR-B 0.05 MG/ML ORAL ÇÖZELTİ, 210 ML ... HEPATOVIR-B 0.5 MG FILM KAPLI TABLET, TABLET, 30 ADET …
Mupirocin
Mupirocin, formerly termed pseudomonic acid A, is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism Pseudomonas fluorescens, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative...
Approved
Investigational
Vet approved
Matched Synonyms: … oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid ... 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3- [(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl] ... Pseudomonic acid A …
Matched Iupac: … }oxan-2-yl]-3-methylbut-2-enoyl]oxy}nonanoic acid ... 9-{[(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-{[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl …
Matched Description: … Mupirocin, formerly termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique ... Produced by fermentation using the organism _Pseudomonas fluorescens_, mupirocin is a naturally-occurring ... mupirocin does not demonstrate cross-resistance with other classes of antimicrobial agents, giving it a …
Matched Mixtures name: … Metronidazole 1% / Mupirocin 2% / ... Metronidazole 1% / Mupirocin 2% ... Metronidazole 1% / Mupirocin 2% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MUPIGEN %2 POMAD , 15 G'LIK 1 TÜP ... Mupirocin 2% ... Bactroban 2 % - Creme …
Matched Iupac: … }oxan-2-yl]-3-methylbut-2-enoyl]oxy}nonanoic acid ... 9-{[(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-{[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl …
Matched Description: … Mupirocin, formerly termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique ... Produced by fermentation using the organism _Pseudomonas fluorescens_, mupirocin is a naturally-occurring ... mupirocin does not demonstrate cross-resistance with other classes of antimicrobial agents, giving it a …
Matched Mixtures name: … Metronidazole 1% / Mupirocin 2% / ... Metronidazole 1% / Mupirocin 2% ... Metronidazole 1% / Mupirocin 2% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MUPIGEN %2 POMAD , 15 G'LIK 1 TÜP ... Mupirocin 2% ... Bactroban 2 % - Creme …
Tobramycin
Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Synonyms: … 3'-Deoxykanamycin B ... -(1-4))-2-deoxy-D-streptamine ... O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl …
Matched Iupac: … (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5 ... -hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol …
Matched Description: … A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a ... ., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive ... A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a …
Matched Salts cas: … 49842-07-1 …
Matched Mixtures name: … TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET ... DEXAVITAL TOBRAMICIDADEXAMETASONA(3 MG+1MG)/ML ... TOBRAZON %0.3 + %0.1 GÖZ DAMLASI, SÜSPANSİYON, 1 ADET …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … Tobramycin B. Braun 3 mg/ml Infusionslösung ... Tobramycin B. Braun 1 mg/ml Infusionslösung ... TOBEL 20 MG/2 ML AMPUL, 3 ADET …
Matched Iupac: … (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5 ... -hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol …
Matched Description: … A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a ... ., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive ... A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a …
Matched Salts cas: … 49842-07-1 …
Matched Mixtures name: … TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET ... DEXAVITAL TOBRAMICIDADEXAMETASONA(3 MG+1MG)/ML ... TOBRAZON %0.3 + %0.1 GÖZ DAMLASI, SÜSPANSİYON, 1 ADET …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … Tobramycin B. Braun 3 mg/ml Infusionslösung ... Tobramycin B. Braun 1 mg/ml Infusionslösung ... TOBEL 20 MG/2 ML AMPUL, 3 ADET …
Alosetron
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Synonyms: … 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable ... In June 2002, the FDA approved a supplemental new drug application allowing the remarketing of the drug …
Matched Salts cas: … 122852-69-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable ... In June 2002, the FDA approved a supplemental new drug application allowing the remarketing of the drug …
Matched Salts cas: … 122852-69-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Beclomethasone dipropionate
Beclomethasone dipropionate is a second-generation synthetic corticosteroid and diester of beclomethasone, which is structurally similar to dexamethasone. It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) which acts on the glucocorticoid receptor to mediates its therapeutic action. Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is...
Approved
Investigational
Matched International brands: … Clenil-A …
Matched Synonyms: … (11β,16β)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione …
Matched Iupac: … ,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl propanoate ... 2-[(1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H …
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... [L6871] It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP)[A179839] which ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone …
Matched Salts cas: … 77011-63-3 …
Matched Mixtures name: … FORMODUAL N. 200/6UG ... FORMODUAL N. 200/6UG ... CANDID-B CREAM …
Matched Products: … RİNOMİL 100 MCG BURUN SPREYİ, SÜSPANSİYON, 1 ŞİŞE …
Matched Synonyms: … (11β,16β)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione …
Matched Iupac: … ,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl propanoate ... 2-[(1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H …
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... [L6871] It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP)[A179839] which ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone …
Matched Salts cas: … 77011-63-3 …
Matched Mixtures name: … FORMODUAL N. 200/6UG ... FORMODUAL N. 200/6UG ... CANDID-B CREAM …
Matched Products: … RİNOMİL 100 MCG BURUN SPREYİ, SÜSPANSİYON, 1 ŞİŞE …
Tadalafil
Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Synonyms: … (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b ... (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido( ... 3,4-b)indole-1,4-dione …
Matched Iupac: … -1(10),11,13,15-tetraene-4,7-dione ... (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca …
Matched Description: … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction ... contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a ... longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Matched Products: … N/A ... REKFİL 20 MG TABLET, 2 ADET ... LONGIVO 20 MG TABLET, 2 TABLET …
Matched Iupac: … -1(10),11,13,15-tetraene-4,7-dione ... (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca …
Matched Description: … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction ... contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a ... longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Matched Products: … N/A ... REKFİL 20 MG TABLET, 2 ADET ... LONGIVO 20 MG TABLET, 2 TABLET …
Venetoclax
Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types...
Approved
Investigational
Matched Synonyms: … 4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro ... 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro ... 4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-(3-nitro …
Matched Iupac: … 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(3-nitro-4-{[(oxan- ... 4-yl)methyl]amino}benzenesulfonyl)-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzamide …
Matched Description: … Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed ... A new indication was approved in 2018 for the treatment patients with chronic lymphocytic leukemia (CLL ... Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. …
Matched Categories: … BCL-2 Inhibitor ... Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(3-nitro-4-{[(oxan- ... 4-yl)methyl]amino}benzenesulfonyl)-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzamide …
Matched Description: … Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed ... A new indication was approved in 2018 for the treatment patients with chronic lymphocytic leukemia (CLL ... Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. …
Matched Categories: … BCL-2 Inhibitor ... Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen …
Matched Name: … Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (propiolactone inactivated) …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Matched Name: … Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (propiolactone inactivated) …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Ramipril
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Synonyms: … (b)pyrrole-2-carboxylic acid ... (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta …
Matched Iupac: … b]pyrrole-2-carboxylic acid ... (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[ …
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … RAMIPRIL COMP HEU 5/25MG N …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … b]pyrrole-2-carboxylic acid ... (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[ …
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … RAMIPRIL COMP HEU 5/25MG N …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Thymol
A phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed)
Approved
Matched Synonyms: … 5-Methyl-2-(1-Methylethyl)Phenol ... 2-isopropyl-5-methylphenol …
Matched Iupac: … 5-methyl-2-(propan-2-yl)phenol …
Matched Description: … A phenol obtained from thyme oil or other volatile oils. ... It is used as a stabilizer in pharmaceutic preparations. ... It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a …
Matched Mixtures name: … VICKS VAPORUB BUHARLASAN MERHEM, 1 ADET …
Matched Products: … Influenza Care Synergy …
Matched Iupac: … 5-methyl-2-(propan-2-yl)phenol …
Matched Description: … A phenol obtained from thyme oil or other volatile oils. ... It is used as a stabilizer in pharmaceutic preparations. ... It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a …
Matched Mixtures name: … VICKS VAPORUB BUHARLASAN MERHEM, 1 ADET …
Matched Products: … Influenza Care Synergy …
Clascoterone
Clascoterone (cortexolone 17α-propionate, CB-03-01) is a novel antagonist of androgen receptors. It binds to androgen receptors with high affinity. By competing with androgens for binding to androgen receptors, clascoterone works by blocking the androgen receptor signalling cascades that promote acne pathogenesis, such as sebaceous gland proliferation, excess sebum production, and...
Approved
Investigational
Matched Synonyms: … 11-deoxycortisol 17α-propionate …
Matched Iupac: … ,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate ... (1R,3aS,3bR,9aR,9bS,11aS)-1-(2-hydroxyacetyl)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH …
Matched Description: … Clascoterone (cortexolone 17α-propionate, CB-03-01) is a novel antagonist of androgen receptors. ... [L15621] Clascoterone is also being investigated as a novel treatment for androgenetic alopecia. …
Matched Iupac: … ,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate ... (1R,3aS,3bR,9aR,9bS,11aS)-1-(2-hydroxyacetyl)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH …
Matched Description: … Clascoterone (cortexolone 17α-propionate, CB-03-01) is a novel antagonist of androgen receptors. ... [L15621] Clascoterone is also being investigated as a novel treatment for androgenetic alopecia. …
Displaying drugs 151 - 175 of 6213 in total