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Displaying drugs 26 - 50 of 3498 in total

Rurioctocog alfa pegol

Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia A to manage and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …

Albutrepenonacog alfa

Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It was also approved by FDA and EMA in 2016. ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] ... [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …

Undecylenic acid

Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat. It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones . Undecylenic acid was...
Approved
Investigational
Matched Synonyms: … 10-undecenoic acid ... Undecenoic acid ... Undecylenic acid …
Matched Name: … Undecylenic acid …
Matched Iupac: … undec-10-enoic acid …
Matched Description: … of ricinoleic acid, and has been polymerized for vinyl production [A32281]. ... ’s foot and relieves itching, burning, and irritation associated with the skin condition. ... Zinc undecylenate is an example of a topical antifungal agent that treats skin infections such as athlete …
Matched Mixtures name: … Zinc Undecylenate ... Zinc Undecylenate ... Fungi Nail Toe and Foot MS …
Matched Salts name: … Zinc undecylenate …
Matched Categories: … Fatty Acids ... undecylenic acid ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated ... undecylenic acid, combinations …
Matched Products: … Undecylenic Acid ... Undecylenic Acid Liquid ... Fungi Nail Toe and Foot Pen …

Aluminum zirconium octachlorohydrex gly

Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Matched Description: … Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and ... It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. …
Matched Mixtures name: … Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN …
Matched Products: … Suave Cocoa Butter Antiperspirant and Deodorant ... Axe Touch Antiperspirant and Deodorant ... Dove Men plus Care Unscented Antiperspirant and Deodorant …

Smallpox and Monkeypox Vaccine, Live, Non-replicating

Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …

Antihemophilic factor (recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Moroctocog alfa

Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … amino acid, 170 kDa protein [FDA Label]. ... purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... Moroctocog alfa is approved by Health Canada and by the European Medicines Agency for the control and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …

Octasulfur

Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli. People take sulfur...
Approved
Matched Description: … Sulfur is also found in garlic, onions and broccoli. ... After calcium and phosphorus, it is the third most abundant mineral in the human body. ... allergies, swelling in the back of the throat (pharyngitis), high cholesterol, clogged arteries, menopause, and …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid ... Dermaharmony Sulfur and Salicylic Acid …
Matched Products: … Spai-sons Acid Anti-dandruff ... Margarite Zinc Cream ... Rodan and Fields Unblemish 1 Wash Acne Medicated Cleanser …

Petrolatum

A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Description: … It is used as an ointment base, topical protectant, and lubricant. …
Matched Mixtures name: … Lil Goats Zinc Oxide ... Glycerin, Lidocaine, Petrolatum, and Phenylephrine Hydrochloride ... Curel Alpha Hydroxy Dry Skin Lotion …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Vitamin A and D ... A and D ... UP and UP …

PMC-403

PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Investigational
Matched Synonyms: … a fully human monoclonal antibody that binds and activates the Tie2 receptor …

TSHA-101

Investigational
Matched Synonyms: … adeno-associated viral vector serotype 9 (AAV9) carrying both HEXA and HEXB …

Coagulation Factor IX (Recombinant)

Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Description: … It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, ... and has structural and functional characteristics similar to those of endogenous factor IX. ... Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric …
Matched Products: … BeneFIX , powder and solvent for solution for injection, 250 IU/Vial. ... BeneFIX Powder and Solvent for Solution for Injection 250iu/vial ... BeneFIX Powder and Solvent for Solution for Injection 1000iu/vial …

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … the pupil,[L9413] and induce local vasoconstriction. ... Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate …
Matched Mixtures name: … Betr Cold and Flu Daytime Relief ... Betr Cold and Flu Nighttime Relief ... Promethazine Hydrochloride and Phenylephrine Hydrochloride …
Matched Salts name: … Phenylephrine hydrochloride …
Matched Categories: … Monoamine Oxidase A Substrates ... Adrenergic and Dopaminergic Agents ... Adrenergic alpha-Agonists ... Mydriatics and Cycloplegics ... Decongestants and Antiallergics …
Matched Products: … Up and Up nasal decongestant PE ... CareOne Cold and Sinus ... Up and Up Sinus PE …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Salts name: … Pasireotide acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (40 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately ... are D-amino acids. …
Matched Salts name: … Degarelix acetate hydrate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …

Menotropins

Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Description: … It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits ... , alpha = 92 residues, beta=111 residues. ... Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … MENOPUR multidose 600IU Powder and Solvent for Solution for Injection ... MENOPUR multidose 1200IU Powder and Solvent for Solution for Injection ... Menopur Powder for Injection and Solvent 75 IU …

Hydroquinone

Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … acids, corticosteroids, retinoids, or sunscreen. ... Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration ... with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and …
Matched Mixtures name: … CREMA CON ACIDO GLICOLICO AL 8% ... Hyaluronic Acid Sodium Salt 1% / Hydroquinone 6% ... Hyaluronic Acid Sodium Salt 0.5% / Hydroquinone 4% / Tretinoin 0.05% …
Matched Products: … Celazome Fade Shades Lightening Cream w/ Glycolic Acid ... CONDITION AND ENHANCE CLEAR Skin Bleaching and Corrector ... CONDITION AND ENHANCE BLENDER Skin Lightener and Blending …

Pseudoephedrine

Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Description: … drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and …
Matched Mixtures name: … FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE …
Matched Salts name: … Pseudoephedrine hydrochloride …
Matched Categories: … Alpha-and Beta-adrenergic Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Adrenergic beta-Agonists ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Pseudoephedrine Hydrochloride ... Pseudoephedrine hydrochloride ... Up and Up Suphedrine …

Selenium Sulfide

Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent...
Approved
Matched Description: … is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and …
Matched Mixtures name: … Clease and Treat …
Matched Products: … Head and Shoulders Itch ... Walgreens Dandruff and Conditioner Cleansing and Conditioning Anti-dandruff ... Head and Shoulders Clinical Strength …

MM-111

MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Synonyms: … Antibody bispecific for erbb2 and erbb3 …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

CLL1-CD33 compound chimeric antigen receptor T cells

Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …

Antihemophilic factor, human recombinant

Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … ADVATE 250IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 500IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 1000IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form ... NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... NOVOSEVEN 1MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... powder and solvent for solution for injection 2mg …

Reteplase

Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and ... the activity-related kringle-2 and serine protease domains of human tPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … enhanced secretion of bile acids and lipids in the feces, patients who take complicated medication regimens ... Bile acid sequestrants like colestipol have been in use since the 1970s. ... [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated …
Matched Salts name: … Colestipol hydrochloride …
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity ... Medications that reduce magnesium levels …
Matched Products: … Colestipol Hydrochloride ... Colestipol hydrochloride …
Displaying drugs 26 - 50 of 3498 in total