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Displaying drugs 26 - 50 of 1335 in total

Tedizolid phosphate

Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … Tedizolid phosphate ... Torezolid phosphate ... fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate …
Matched Name: … Tedizolid phosphate …
Matched Description: … Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate …

Estramustine phosphate

A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Approved
Investigational
Matched Synonyms: … Estramustine 17-(dihydrogen phosphate) …
Matched Name: … Estramustine phosphate …
Matched Description: … A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also …

Tetracycline phosphate complex

Approved
Matched Synonyms: … Tetracycline phosphate complex …
Matched Name: … Tetracycline phosphate complex …

Menadiol diphosphate

Approved
Nutraceutical
Matched Synonyms: … Menadiol phosphate ... Menadiol bis(dihydrogen phosphate) …
Matched Salts name: … Menadiol sodium diphosphate …

Thimerosal

Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes...
Approved
Matched Synonyms: … sodium merthiolate ... ethylmercurithiosalicylate sodium ... sodium ethylmercurithiosalicylate …
Matched Iupac: … sodium [(2-carboxylatophenyl)sulfanyl](ethyl)mercury …

Cyclothiazide

As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Synonyms: … 6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Description: … its action on carbonic anhydrases in the smooth muscle or through its action on the large-conductance calcium-activated ... binding to the thiazide sensitive sodium-chloride transporter. ... This results in an increase in potassium excretion via the sodium-potassium exchange mechanism. …

Codeine

The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease...
Approved
Illicit
Matched Mixtures name: … Acetaminophen and Codeine Phosphate ... Acetaminophen and Codeine Phosphate ... Codeine Phosphate Guaifenesin …
Matched Salts name: … Codeine phosphate ... Codeine phosphate hemihydrate …
Matched Products: … CODEINE PHOSPHATE HEMIHYDRATE ... Codeine Phosphate Syrup ... Codeine Phosphate Tab 30mg …

Docusate

Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched Mixtures name: … Calcium Docuphen Cap ... Senna/Docusate Sodium ... Docusate Sodium …
Matched Salts name: … Docusate calcium ... Docusate sodium …
Matched Products: … Docusate Calcium 240 mg sodium free ... Docusate Calcium ... Docusate calcium …

Levoleucovorin

Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Salts name: … Levoleucovorin calcium ... Levoleucovorin calcium pentahydrate …
Matched Categories: … sodium levofolinate ... calcium levofolinate ... Leucovorin Calcium-Levoleucovorin …
Matched Products: … Levoleucovorin Calcium …

Tolevamer

Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched Description: … Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. …
Matched Salts name: … Tolevamer calcium ... Tolevamer sodium ... Tolevamer potassium sodium …
Matched Products: … Resonium Calcium ... CALCIUM POLYSTYRENE SULFONATE ... Jamp Calcium Polystyrene Sulfonate …

Mupirocin

Mupirocin, formerly termed pseudomonic acid A, is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism Pseudomonas fluorescens, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative...
Approved
Investigational
Vet approved
Matched Salts name: … Mupirocin calcium …
Matched Products: … Mupirocin Calcium ... MUPIROCIN CALCIUM …

Fosamprenavir

Fosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.
Approved
Matched Salts name: … Fosamprenavir calcium ... Fosamprenavir sodium …
Matched Products: … Fosamprenavir Calcium …

Estramustine

A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Approved
Investigational
Matched Description: … A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also …
Matched Salts name: … Estramustin sodium phosphate …

Primaquine

An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of...
Approved
Matched Salts name: … Primaquine phosphate …
Matched Products: … Primaquine Phosphate ... PRIMAQUINE PHOSPHATE …

Teriparatide

Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Categories: … Calcium Homeostasis ... Calcium-Regulating Hormones and Agents …

Atorvastatin

Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Mixtures name: … Amlodipine besylate/atorvastatin calcium ... Amlodipine besylate/atorvastatin calcium ... Amlodipine besylate/atorvastatin calcium …
Matched Salts name: … Atorvastatin calcium ... Atorvastatin calcium trihydrate …
Matched Products: … Atorvastatin Calcium ... Atorvastatin calcium ... ATORVASTATIN CALCIUM …

Fospropofol

Fospropofol is a water soluble prodrug and is converted to propofol in the liver. Fospropofol is a short acting hypnotic/sedative/anesthetic agent. Unlike propofol, does not cause injection-site pain as it is unable to activate TRPA1. FDA approved in December 2008. Fospropofol is a Schedule IV controlled substance in the United...
Approved
Illicit
Investigational

Amlodipine

Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Description: … in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium ... Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are ... associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than other calcium …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine besylate/atorvastatin calcium ... Amlodipine besylate/atorvastatin calcium …
Matched Categories: … Calcium Channel Blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) …
Matched Products: … AMLODIGAMMA TOP 5MG ... AMLODIGAMMA TOP 10MG …

Fingolimod

Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Matched Description: … [A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting …
Matched Categories: … Sphingosine 1-phosphate Receptor Modulator ... Sphingosine 1 Phosphate Receptor Modulators ... Sphingosine-1-phosphate (S1P) receptor modulators …

Nitrendipine

Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Description: … does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive. ... Nitrendipine is a calcium channel blocker with marked vasodilator action. ... It is an effective antihypertensive agent and differs from other calcium channel blockers in that it …
Matched Categories: … Calcium Channel Blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Selective Calcium Channel Blockers With Mainly Vascular Effects …

Lercanidipine

Lercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Approved
Investigational
Matched Description: … Lercanidipine is a calcium channel blocker of the dihydropyridine class. …
Matched Categories: … Calcium Channel Blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Selective Calcium Channel Blockers With Mainly Vascular Effects …

Amifampridine

Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium concentrations . It was first discovered in Scotland in the 1970s and its clinical effectiveness for neuromuscular disorders, including Lambert–Eaton myasthenic syndrome (LEMS), has been investigated...
Approved
Investigational
Matched Description: … Amifampridine phosphate is a more stable salt that serves as an active ingredient of EMA-approved Firdapse ... , leading to decreased presynaptic calcium levels and reduced quantal release of acetylcholine, which ... presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium …
Matched Salts name: … Amifampridine phosphate …

Alendronic acid

Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Salts name: … Alendronate calcium ... Alendronate sodium ... Alendronate sodium anhydrous …
Matched Categories: … alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … Alendronate Sodium ... Ag-alendronate Sodium ... Jamp Alendronate Sodium …

Carvedilol

Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as...
Approved
Investigational
Matched Salts name: … Carvedilol phosphate …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Matched Products: … Carvedilol Phosphate …

Doxycycline

Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Matched Salts name: … Doxycycline calcium …
Matched Products: … Vibramycin Calcium …
Displaying drugs 26 - 50 of 1335 in total