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Displaying drugs 51 - 75 of 1187 in total

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … receptors in the pituitary gland and blocks interaction with GnRH. ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately ... Reduction in testosterone is important in treating men with advanced prostate cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …

Antihemophilic factor (recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... 2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Compounds used in a research, industrial, or household setting …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Acetaminophen

Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Description: … and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). ... FDA in 1951 and is available in a variety of forms including syrup form, regular tablets, effervescent ... of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines …
Matched Mixtures name: … ALPARA ... ALPARA ... Neocitran Extra Strength Cold & Sinus Night - Apple Cinnamon …
Matched Categories: … Acetaminophen and Prodrugs ... tramadol and paracetamol ... codeine and paracetamol ... oxycodone and paracetamol ... hydrocodone and paracetamol …
Matched Products: … Good Sense Pain and Fever ... Good Sense pain and fever ... Good Sense Pain and Fever Infants …

Reteplase

Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and ... Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … RAPILYSIN 10 U IV ENJ. ICIN STERIL LIYOFILIZE TOZ ICEREN FLAKON, 2 ADET …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces, patients ... the gut environment because it undergoes little absorption and metabolism. ... [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Menotropins

Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Description: … It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits ... Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the ... , alpha = 92 residues, beta=111 residues. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Menopur Powder for Injection and Solvent 75 IU ... GYNOGEN HP 75 IU Powder and Solvent for Solution for Injection (Menotrophin for Injection BP, 75 IU/ ... GYNOGEN HP 150 IU Powder and Solvent for Solution for Injection (Menotrophin for injection BP, 150 IU …

MM-111

MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Synonyms: … Antibody bispecific for erbb2 and erbb3 …
Matched Description: … family receptor tyrosine kinases, ERBB2 and ERBB3. ... MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor …
Matched Categories: … Amino Acids, Peptides, and Proteins …

CLL1-CD33 compound chimeric antigen receptor T cells

Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …

Selenium Sulfide

Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent...
Approved
Matched Synonyms: … Selenium(IV) sulfide ... Selenium(IV) sulphide ... Selenium(IV) disulfide …
Matched Description: … dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent children ... cells in seborrhea. ... Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic …
Matched Mixtures name: … Clease and Treat …
Matched Products: … Selsun Blue 2-in-1 ... Selsun Blue, 2-IN-1 ... Head and Shoulders Itch …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Description: … It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease ... Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (40 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …

Calcium carbonate

Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also...
Approved
Investigational
Matched Description: … An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. ... It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. ... Calcium carbonate is an inorganic salt used as an antacid. …
Matched Mixtures name: … Heartburn and gas fruit chews ... Cavan Alpha ... Good Night/pm Formula Tab …
Matched Categories: … Alimentary Tract and Metabolism ... Antacids and Adsorbents ... ascorbic acid (vit C) and calcium …
Matched Products: … CVS PHARMACY,INC. Assorted Fruit ... up and up extra strength smooth dissolving antacid Assorted Fruit ... Good Sense Antacid …

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … the pupil,[L9413] and induce local vasoconstriction. ... Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate ... [A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s …
Matched Mixtures name: … Neocitran Extra Strength Cold & Sinus Night - Apple Cinnamon ... Children's Coltalin Fruit Flavor Chewable Cold Tablets ... Benylin All-IN-one Cold and Flu Night PE Caplets …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Adrenergic alpha-Agonists ... Mydriatics and Cycloplegics ... Decongestants and Antiallergics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Good Sense Nasal Four ... Smart Sense Sinus PE ... CareOne Cold and Sinus …

Antihemophilic factor, human recombinant

Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … ADVATE 250 IU Powder and Solvent for Solution for Injection ... ADVATE 500 IU Powder and Solvent for Solution for Injection ... ADVATE 1000 IU Powder and Solvent for Solution for Injection …

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form ... NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Increased Coagulation Factor IX Activity …
Matched Products: … NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... NOVOSEVEN 1MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... powder and solvent for solution for injection 2mg …

Turoctocog alfa

Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally ... secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid 720, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …

Viagenpumatucel-L

Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Gp96-igg1-fc fusion protein and hla-a1 expressing, irradiated ad-100 whole cell vaccine …
Matched Description: … Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l ... (HS-110) in Patients With Non-small Cell Lung Cancer). …

DCVAC/OvCa

DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … and matured by TLR3 ligand _ex vivo_. ... It is under investigation for the treatment of ovarian cancer. ... DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells …

CHF5633

CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … ), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic ... CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Romilkimab

Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Investigational
Matched Synonyms: … Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13) …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in …

Carbidopa

Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Synonyms: … (-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate …
Matched Description: … It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does ... approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and ... Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. …
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …

Capsaicin

Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent...
Approved
Matched Description: … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, ... and patch preparations of various strengths; however, it may also be found in some dietary supplements ... Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical …
Matched Mixtures name: … Cajun Hot Ice Muscle and Joint Pain Rub ... Satohap Cool and Hot Pads ... Zostrix Diabetic Joint and Arthritis Pain Relief …
Matched Categories: … Basic Lotions and Liniments ... Capsaicin and Similar Agents ... Topical Products for Joint and Muscular Pain …
Matched Products: … MINTED LEAF Heat Therapy Roll-On with Capsaicin and CBD ... Sherman and Clark Pain Relieving ... Miracle Plus Neck and Shoulder Pain Relief …

Allantoin

Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Description: … Allantoin is a substance that is endogenous to the human body and also found as a normal component of ... Allantoin is found in OTC cosmetic products and other commercial products such as oral hygiene products ... , in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions [A32213]. …
Matched Mixtures name: … Fruit of the Earth Cool Blue Aloe Vera Cooling ... Aspiera Wound Care and Antiseptic ... Aspiera Wound Care and Antiseptic …
Matched Categories: … Basic Ointments and Protectants ... Herbs and Natural Products …
Matched Products: … Vital Fluid II EGF and FGF Whitening Serum ... Sang Leaf Ginseng Collagen ... Natural Ice Healer …

Doxylamine

Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Approved
Vet approved
Matched Synonyms: … 2-(alpha-(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine …
Matched Description: … It is used in allergies and as an antitussive, antiemetic, and hypnotic. ... Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism …
Matched Mixtures name: … Up and Up Daytime Vapor Ice Cold and Flu Nighttime Vapor Ice Cold and Flu ... Up and Up Daytime Vapor Ice Cold and Flu Nighttime Vapor Ice Cold and Flu ... Good Sense Night Time Cold and Flu …
Matched Products: … Berkley and Jensen Sleep Aid ... Up and Up Nighttime Sleep Aid ... Good sense sleep aid …

Eupatorium capillifolium pollen

Eupatorium capillifolium pollen is the pollen of the Eupatorium capillifolium plant. Eupatorium capillifolium pollen is mainly used in allergenic testing.
Approved
Matched Description: … Eupatorium capillifolium pollen is mainly used in allergenic testing. ... Eupatorium capillifolium pollen is the pollen of the Eupatorium capillifolium plant. …
Matched Categories: … Increased IgG Production …
Matched Products: … Pollens - Weeds and Garden Plants, Dog Fennel, Eastern Eupatorium capillifolium ... Pollens - Weeds and Garden Plants, Dog Fennel Eupatorium capillifolium …

ARGX-119

ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Investigational
Matched Synonyms: … humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and …
Matched Description: … ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK). …
Displaying drugs 51 - 75 of 1187 in total