Displaying drugs 51 - 75 of 13779 in total
Gefitinib
Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Synonyms: … 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline ... N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine …
Matched Iupac: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine …
Matched Description: … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. ... proteins in malignant cells. ... Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine …
Matched Description: … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. ... proteins in malignant cells. ... Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Norfloxacin
A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Approved
Matched Synonyms: … 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsäure ... 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Metabolic Side Effects of Drugs and Substances …
Doxycycline
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Matched Synonyms: … 5-hydroxy-α-6-deoxytetracycline ... 6-alpha-deoxy-5-oxytetracycline …
Matched Iupac: … 6,11,12a-octahydrotetracene-2-carboxamide ... (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a, …
Matched Description: … [L42880] It is a second-generation tetracycline that was first discovered in 1967. ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections …
Matched Categories: … combinations of tetracyclines …
Matched Iupac: … 6,11,12a-octahydrotetracene-2-carboxamide ... (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a, …
Matched Description: … [L42880] It is a second-generation tetracycline that was first discovered in 1967. ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections …
Matched Categories: … combinations of tetracyclines …
Ofloxacin
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Synonyms: … 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic …
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Description: … synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Description: … synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Metabolic Side Effects of Drugs and Substances …
Mavacamten
Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. Mavacamten was also approved...
Approved
Investigational
Matched Synonyms: … 6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used ... in humans. ... Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart …
Matched Iupac: … 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used ... in humans. ... Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart …
Lidocaine
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched International brands: … Lidoject-2 …
Matched Synonyms: … 2-(Diethylamino)-2',6'-acetoxylidide ... 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide …
Matched Iupac: … 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide …
Matched Description: … In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations ... It is even included in the World Health Organization's List of Essential Medicines [L6055]. ... of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical …
Matched Mixtures name: … Point Of Care LM DEP 2 ... DOLOPROCT SUPOZITUVAR, 6 ADET ... Point Of Care L2 …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Fruit of the Earth Sun Town City ... Fruit of the Earth Aloe Vera Cool Blue ... Lidocain Aguettant 10 mg/ml Injektionslösung in einer Fertigspritze …
Matched Synonyms: … 2-(Diethylamino)-2',6'-acetoxylidide ... 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide …
Matched Iupac: … 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide …
Matched Description: … In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations ... It is even included in the World Health Organization's List of Essential Medicines [L6055]. ... of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical …
Matched Mixtures name: … Point Of Care LM DEP 2 ... DOLOPROCT SUPOZITUVAR, 6 ADET ... Point Of Care L2 …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Fruit of the Earth Sun Town City ... Fruit of the Earth Aloe Vera Cool Blue ... Lidocain Aguettant 10 mg/ml Injektionslösung in einer Fertigspritze …
Fluorescein
A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Synonyms: … 3',6'-dihydroxyfluoran ... 9-(o-carboxyphenyl)-6-hydroxy-3-isoxanthenone ... 9-(o-carboxyphenyl)-6-hydroxy-3H-xanthen-3-one …
Matched Iupac: … 3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one …
Matched Description: … A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline ... It has been approved by FDA for use in externally applied drugs and cosmetics. ... medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Matched Products: … MINIMS FLUORESCEIN SODIUM EYE DROPS 2% w/v …
Matched Iupac: … 3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one …
Matched Description: … A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline ... It has been approved by FDA for use in externally applied drugs and cosmetics. ... medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Matched Products: … MINIMS FLUORESCEIN SODIUM EYE DROPS 2% w/v …
Lenvatinib
Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). Lenvatinib also inhibits other RTKs that have been implicated in pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellular...
Approved
Investigational
Matched Synonyms: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Iupac: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Description: … and increased expression of VEGF is associated with a poor prognosis in many types of cancers. ... of signal transduction pathways involved in the normal regulation of cellular processes, such as cell ... factor (FGF) receptors FGFR1, 2, 3, and 4; the platelet derived growth factor receptor alpha (PDGFRα) …
Matched Salts cas: … 857890-39-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Description: … and increased expression of VEGF is associated with a poor prognosis in many types of cancers. ... of signal transduction pathways involved in the normal regulation of cellular processes, such as cell ... factor (FGF) receptors FGFR1, 2, 3, and 4; the platelet derived growth factor receptor alpha (PDGFRα) …
Matched Salts cas: … 857890-39-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Vidarabine
A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the vaccinia VIRUS and varicella zoster virus.
Approved
Investigational
Matched Synonyms: … 9-beta-D-arabinofuranosyl-9H-purin-6-amine ... 9-β-D-arabinofuranosyl-9H-purin-6-amine …
Matched Iupac: … (2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Description: … It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures ... and significant antiviral activity against infections caused by a variety of viruses such as the herpes …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Description: … It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures ... and significant antiviral activity against infections caused by a variety of viruses such as the herpes …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Amlodipine
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Synonyms: … (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate ... 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Amlodipine is commonly used in the treatment of high blood pressure and angina. ... Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the ... The option for single daily dosing of amlodipine is an attractive feature of this drug [FDA label]. …
Matched Salts cas: … 111470-99-6 ... 652969-01-2 …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Amlodipine is commonly used in the treatment of high blood pressure and angina. ... Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the ... The option for single daily dosing of amlodipine is an attractive feature of this drug [FDA label]. …
Matched Salts cas: … 111470-99-6 ... 652969-01-2 …
Dihydroergotamine
A 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect profile.
Recent improvements have been made in the design of intranasal delivery devices allowing...
Approved
Investigational
Matched Synonyms: … 5'-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman ... 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione ... (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6] …
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6 ... }]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene …
Matched Description: … 3-fold in Cmax and 4-fold in AUC despite the solution formulated at 75% of the strength of the existing ... Recent improvements have been made in the design of intranasal delivery devices allowing for greater ... A 9,10alpha-dihydro derivative of [ergotamine]. …
Matched Salts cas: … 6190-39-2 …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6 ... }]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene …
Matched Description: … 3-fold in Cmax and 4-fold in AUC despite the solution formulated at 75% of the strength of the existing ... Recent improvements have been made in the design of intranasal delivery devices allowing for greater ... A 9,10alpha-dihydro derivative of [ergotamine]. …
Matched Salts cas: … 6190-39-2 …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Sulfur hexafluoride
Sulfur hexafluoride is an ultrasound contrast agent indicated for use
•in echocardiography to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border in adult patients with suboptimal echocardiograms
•in ultrasonography of the liver for characterization of focal liver lesions in adult and pediatric...
Approved
Matched Synonyms: … sulfur(6+) fluoride …
Matched Description: … of focal liver lesions in adult and pediatric patients ... in adult patients with suboptimal echocardiograms •in ultrasonography of the liver for characterization ... the left ventricular chamber and to improve the delineation of the left ventricular endocardial border …
Matched Description: … of focal liver lesions in adult and pediatric patients ... in adult patients with suboptimal echocardiograms •in ultrasonography of the liver for characterization ... the left ventricular chamber and to improve the delineation of the left ventricular endocardial border …
Tedizolid phosphate
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … [(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl …
Matched Iupac: … {[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin- …
Matched Description: … [A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the ... Tedizolid is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … SİVEXTRO 200 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 6 ADET …
Matched Iupac: … {[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin- …
Matched Description: … [A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the ... Tedizolid is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … SİVEXTRO 200 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 6 ADET …
Linzagolix
Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis.[A253642,A253647] It is similar to other GnRH receptor antagonists like cetrorelix, relugolix, and elagolix.
Uterine fibroids occur in >70% of women of reproductive...
Approved
Matched Synonyms: … 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno ... Thieno(3,4-d)pyrimidine-5-carboxylic acid, 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl …
Matched Iupac: … 3-{5-[(2,3-difluoro-6-methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl}-2,4-dioxo-1H,2H,3H,4H-thieno[3,4 …
Matched Description: … [A253667] Linzagolix was approved for use in the European Union in June 2022 for the management of ... Uterine fibroids occur in >70% of women of reproductive age, and when symptomatic are associated with ... receptor antagonists like linzagolix - are thought to be beneficial by preventing intramyometrial growths in …
Matched Salts cas: … 1321816-57-2 …
Matched Iupac: … 3-{5-[(2,3-difluoro-6-methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl}-2,4-dioxo-1H,2H,3H,4H-thieno[3,4 …
Matched Description: … [A253667] Linzagolix was approved for use in the European Union in June 2022 for the management of ... Uterine fibroids occur in >70% of women of reproductive age, and when symptomatic are associated with ... receptor antagonists like linzagolix - are thought to be beneficial by preventing intramyometrial growths in …
Matched Salts cas: … 1321816-57-2 …
Factor IX Complex (Human)
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … factors found in functioning human plasma. ... factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients experiencing ... Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting …
Matched Description: … factors found in functioning human plasma. ... factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients experiencing ... Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting …
Abacavir
Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.
Approved
Investigational
Matched Synonyms: … {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol …
Matched Iupac: … [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol …
Matched Description: … In vivo, abacavir sulfate dissociates to its free base, abacavir. …
Matched Salts cas: … 188062-50-2 …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol …
Matched Description: … In vivo, abacavir sulfate dissociates to its free base, abacavir. …
Matched Salts cas: … 188062-50-2 …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Heterocyclic Compounds, 2-Ring …
Pyrethrum extract
Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins component of rid mousse …
Matched Description: … While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities ... Pyrethrin refers to a more refined extract of pyrethrum. ... Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities ... Pyrethrin refers to a more refined extract of pyrethrum. ... Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Doconexent
A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and...
Approved
Investigational
Matched Synonyms: … 22:6(n-3) ... 22:6-4, 7,10,13,16,19 …
Matched Description: … DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. ... , and retina thus plays an important role in their development and function. ... A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement …
Matched Mixtures name: … Herbs of Gold Salmon Oil 1000 mg ... VemaVite-PRx 2 with Fish-Based DHA ... Tricare Prenatal 2-part Daily Prenatal Vitamin System …
Matched Description: … DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. ... , and retina thus plays an important role in their development and function. ... A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement …
Matched Mixtures name: … Herbs of Gold Salmon Oil 1000 mg ... VemaVite-PRx 2 with Fish-Based DHA ... Tricare Prenatal 2-part Daily Prenatal Vitamin System …
Lumacaftor
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. ... Mutations in the CFTR gene result in altered production, misfolding, or function of the CFTR protein ... gene for the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, a transmembrane ion …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. ... Mutations in the CFTR gene result in altered production, misfolding, or function of the CFTR protein ... gene for the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, a transmembrane ion …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cloxacillin
A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1- ... azabicyclo[3.2.0]heptane-2-carboxylic acid ... 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Description: … A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin]. …
Matched Categories: … combinations of penicillins ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Description: … A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin]. …
Matched Categories: … combinations of penicillins ... Heterocyclic Compounds, 2-Ring …
Bosutinib
Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Synonyms: … 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile …
Matched Iupac: … 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile …
Matched Description: … [A6901,A17961] Bosutinib was first approved by the FDA in 2012 for the treatment of adult chronic, ... in a BCR-ABL fusion protein. ... [L48436] On September 26, 2023, bosutinib was also approved by the FDA for the treatment of pediatric …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile …
Matched Description: … [A6901,A17961] Bosutinib was first approved by the FDA in 2012 for the treatment of adult chronic, ... in a BCR-ABL fusion protein. ... [L48436] On September 26, 2023, bosutinib was also approved by the FDA for the treatment of pediatric …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Omidenepag isopropyl
Omidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension. Omidenepag isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule with high selectivity and agonistic activity towards the prostaglandin E2 (EP2) receptor.[A253263,A253268] Prostanoid FP receptor agonists (FP...
Approved
Investigational
Matched Synonyms: … isopropyl N-(6-(((4-(1H-pyrazol-1-yl)benzyl)(3-pyridinylsulfonyl)amino)methyl)-2-pyridinyl)glycinate …
Matched Iupac: … propan-2-yl 2-({6-[(N-{[4-(1H-pyrazol-1-yl)phenyl]methyl}pyridine-3-sulfonamido)methyl]pyridin-2-yl}amino …
Matched Description: … [A253253] In 2018, omidenepag isopropyl was approved in Japan for the treatment of glaucoma and ocular ... [A253268] In September 2022, the FDA approved the use of omidenepag isopropyl.[L43503] ... The use of an EP2 receptor agonist such as omidenepag represents an alternative in these scenarios. …
Matched Categories: … combinations of sulfonamides …
Matched Iupac: … propan-2-yl 2-({6-[(N-{[4-(1H-pyrazol-1-yl)phenyl]methyl}pyridine-3-sulfonamido)methyl]pyridin-2-yl}amino …
Matched Description: … [A253253] In 2018, omidenepag isopropyl was approved in Japan for the treatment of glaucoma and ocular ... [A253268] In September 2022, the FDA approved the use of omidenepag isopropyl.[L43503] ... The use of an EP2 receptor agonist such as omidenepag represents an alternative in these scenarios. …
Matched Categories: … combinations of sulfonamides …
Lisuride
An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).
Approved
Investigational
Matched Synonyms: … N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea …
Matched Iupac: … 3,3-diethyl-1-[(4S,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14 …
Matched Salts cas: … 19875-60-6 …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Iupac: … 3,3-diethyl-1-[(4S,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14 …
Matched Salts cas: … 19875-60-6 …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Netupitant
Netupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy including highly emetogenic chemotherapy. Netupitant is a neurokinin 1 receptor antagonist. The combination drug is marketed by Eisai...
Approved
Investigational
Matched Synonyms: … 2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl …
Matched Iupac: … 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin …
Matched Description: … Netupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron ... for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy including …
Matched Iupac: … 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin …
Matched Description: … Netupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron ... for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy including …
Displaying drugs 51 - 75 of 13779 in total