Displaying drugs 76 - 100 of 9330 in total
Magnesium citrate
Magnesium citrate is a low volume and osmotic cathartic agent. The cathartic action works primarily through the high osmolarity of the solution which draws large amounts of fluid into space where is used. Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug products under...
Approved
Matched Description: … [T215] Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug ... Magnesium citrate is a low volume and osmotic cathartic agent. ... [L2831] It is also considered as an active ingredient in over-the-counter products.[L1113] …
Pegloticase
Pegloticase is a porcine recombinant PEGylated uricase indicated for the treatment of chronic gout in adult patients that do not respond to other types of therapies. Pegloticase has a similar activity to rasburicase, an enzyme that metabolizes uric acid to allantoin. In gout patients treated with pegloticase, the conversion of...
Approved
Investigational
Matched Description: … [A249980] The PEG group also gives pegloticase a lower potential to induce an immune response. ... [L42425] Pegloticase was approved by the FDA in 2014, and in 2022, the drug label included the co-administration ... [L42425] Pegloticase has a similar activity to rasburicase, an enzyme that metabolizes uric acid to allantoin …
Ganciclovir
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Description: … An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. …
Propoxycaine
Propoxycaine is a local anesthetic of the ester type that has a rapid onset of action and a longer duration of action than procaine hydrochloride . This drug was removed from the US market in 1996. Although no longer available in the United States, this medication was used in combination...
Approved
Ciltacabtagene autoleucel
Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000, and is variable in its presentation - some patients may remain entirely asymptomatic, while others may experience a range of symptoms including...
Approved
Investigational
Matched Description: … It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000,[L40749] and is ... [A245854] Carvykti was first approved by the FDA in February 2022 for the treatment of relapsed or refractory …
Bicisate
Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester. It is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl...
Approved
Investigational
Matched Description: … A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved …
Matched Categories: … Radioactive Diagnostic Agent …
Matched Categories: … Radioactive Diagnostic Agent …
Metformin
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173]
Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... [A36559]
Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval ... [L12207,A176173]
Metformin is considered an antihyperglycemic drug because it lowers blood glucose …
Matched Products: … METFORMINA EG STADA GROUP …
Matched Products: … METFORMINA EG STADA GROUP …
Iopromide
Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs. Although iopromide can cause several serious adverse effects, including...
Approved
Matched Description: … It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, ... [A260751]
Approved by the FDA in 1995 and Health Canada in 1994 under the brand name ULTRAVIST, iopromide ... Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. …
Matched Categories: … Radiographic Contrast Agent …
Matched Categories: … Radiographic Contrast Agent …
Mafenide
Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns. In 1998, mafenide acetate was approved under the FDA’s accelerated approval regulations. In November 2022, the use of mafenide acetate (powder...
Approved
Vet approved
Withdrawn
Matched Description: … Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. ... [L36773] In 1998, mafenide acetate was approved under the FDA’s accelerated approval regulations. ... 2022, the use of mafenide acetate (powder for 5% topical solution) was withdrawn by the FDA due to an …
Lidocaine
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched Description: … Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an ... As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. ... principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent …
Amlodipine
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Description: … group of drugs called _dihydropyridine calcium channel blockers_. ... Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the ... an important vasodilator that decreases blood pressure [A175321]. …
Praziquantel
Praziquantel is a pyrazino-isoquinolein derivative from the thioxantonic group used as a broad anthelmintic spectrum. Specifically, it is known as a treatment of trematodes and cestodes infections such as schistosomiasis, taeniasis, and cysticercosis. The efficacy of praziquantel in treating parasitic flatworms infection with low cost (~US$0.20 drug cost to treat...
Approved
Investigational
Vet approved
Matched Description: … Praziquantel is a pyrazino-isoquinolein derivative from the thioxantonic group used as a broad anthelmintic ... treating parasitic flatworms infection with low cost (~US$0.20 drug cost to treat a child) makes it an ... [A263206,A263211] Despite being approved since 1980, the exact mechanism of action is yet to be elucidated …
Plantago seed
Platango seeds refer to the seeds collected from various species of plantago trees. It is found in some laxatives for treating occasional constipation and restoring regularity in bowel movements. Its potential benefit in maintaining remission in ulcerative colitis has been studied .
Regardless, this agent is most predominantly used as...
Approved
Investigational
Matched Description: … Regardless, this agent is most predominantly used as a gentle laxative agent in many parts of the world …
Fluoride ion F-18
Sodium Fluoride F 18 Injection is a positron emitting radiopharmaceutical, no-carrier added. It contains radioactive fluoride F 18 that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging and is administered by intravenous injection. Its primary indication is for bone imaging. Increased deposition around joints can...
Approved
Matched Categories: … Radioactive Diagnostic Agent …
Belinostat
Belinostat is a novel agent that inhibits the enzyme histone deacetylase (HDAC) with a sulfonamide-hydroxamide structure. It was developed as an orphan drug to target hematological malignancies and solid tumors by TopoTarget. The safety and efficacy of belinostat is currently being evaluated for use in combination with traditional front-line therapies...
Approved
Investigational
Matched Description: … It was US-approved in July 2014 as a therapeutic agent for relapsed or refractory peripheral T-cell lymphoma ... It was developed as an orphan drug to target hematological malignancies and solid tumors by TopoTarget ... Belinostat is a novel agent that inhibits the enzyme histone deacetylase (HDAC) with a sulfonamide-hydroxamide …
Tebentafusp
Tebentafusp is a gp100 peptide-HLA-directed CD3 T cell engager. It is a bispecific, fusion protein and first-in-class drug of immune-mobilizing monoclonal T cell receptors against cancer (ImmTACs), a recently developed cancer immunotherapy with a novel mechanism of action. ImmTACs bind to target cancer cells that express a specific antigen of...
Approved
Investigational
Matched Description: … [L39995] Tebentafusp was subsequently approved for the same indication in the EU in April 2022. ... [A244815] On January 26, 2022, tebentafusp was first approved by the FDA for the treatment of HLA-A*02 ... This approval marks the first bispecific T cell engager to be approved by the FDA to treat a solid tumour …
Bismuth subnitrate
Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent . The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.
Approved
Matched Description: … The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the ... water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent …
Porfimer sodium
The purified component of hematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins. It is used in photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with visible light and experimentally as an antiviral agent. It is the first drug to be approved in the use of photodynamic therapy in...
Approved
Investigational
Matched Description: … antiviral agent. ... It is the first drug to be approved in the use of photodynamic therapy in the United States. ... hematoporphyrin photoradiation); to treat malignant lesions with visible light and experimentally as an …
Lubiprostone
Lubiprostone is a medication used in the management of idiopathic chronic constipation. A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastrointestinal epithelial cells. Activation of these channels promotes the secretion of a chloride-rich fluid that soften...
Approved
Investigational
Sulodexide
Sulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).
Approved
Investigational
Matched Categories: … Heparin Group …
Methylprednisolone aceponate
Approved
Vet approved
Matched Categories: … Corticosteroids, Potent (Group III) …
Sodium tetradecyl sulfate
An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
Approved
Investigational
Matched Description: … An anionic surface-active agent used for its wetting properties in industry and used in medicine as an ... irritant and sclerosing agent for hemorrhoids and varicose veins. …
Enoxaparin
Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies. Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients...
Approved
Matched Description: … Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection …
Matched Categories: … Heparin Group …
Matched Categories: … Heparin Group …
Bethanidine
A guanidinium antihypertensive agent that acts by blocking adrenergic transmission.
Approved
Matched Description: … A guanidinium antihypertensive agent that acts by blocking adrenergic transmission. …
Displaying drugs 76 - 100 of 9330 in total