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Displaying drugs 151 - 175 of 14789 in total

Dienestrol

Dienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of...
Approved
Investigational
Matched Description: … the vagina (atrophic vaginitis), and inflammation of the urethra (atrophic urethritis). ... Dienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. ... , or soreness of the vulva. …
Matched Categories: … Sex Hormones and Modulators of the Genital System ... Estrogens, Non-Steroidal ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Lisocabtagene maraleucel

Lisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to brexucabtagene autoleucel and axicabtagene ciloleucel.[A228493,L31588] Lisocabtagene maraleucel is a genetically modified autologous T-cell therapy that targets CD19, the B-lymphocyte surface antigen B4. CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing survival rates over standard...
Approved
Matched Description: … maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to [brexucabtagene autoleucel] and ... [A228493] Lisocabtagene maraleucel was granted FDA approval on 5 February 2021 [L31583] and EC approval ... [A228493] However, data on the efficacy of CAR T-cell therapies on less severe forms of B-cell lymphoma …

Naphazoline

Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations ... Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles …
Matched Mixtures name: … FENIXIL-OF ... Lubricant and Redness Reliever ... Eye Drops Redness and Dry Eye Relief …
Matched Categories: … Decongestants and Antiallergics …

Polygala senega root

Approved
Experimental
Matched Categories: … Cough and Cold Preparations …

Cromoglicic acid

A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Approved
Matched Description: … It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect ... A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells …
Matched Categories: … Alimentary Tract and Metabolism ... Decongestants and Antiallergics ... reproterol and sodium cromoglicate ... salbutamol and sodium cromoglicate …
Matched Products: … ALEFH-OF …

Tafasitamab

Tafasitamab is a humanized, CD19-directed cytolytic monoclonal antibody intended for the treatment of B-cell malignancies. It is produced using recombinant DNA technology in Chinese hamster ovary cells, and contains an IgG1/2 hybrid Fc-domain which has been modified with 2 amino acid substitutions to enhance its cytotoxicity relative to non-engineered anti-CD19...
Approved
Investigational
Matched Description: … results in the lysis of B-cells (both healthy and malignant). ... [L15302] Its relative ubiquity across different stages of B-cell development, including pre-B and mature ... Tafasatimab is designed to bind to and block the activity of the CD19 surface antigen, which ultimately …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Clostridium tetani toxoid antigen (formaldehyde inactivated)

Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus. The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium sulfate filtration...
Approved
Matched Description: … It is used for active immunization of children 7 years of age or older, and adults, for prevention of ... sulfate filtration and precipation. ... The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium …
Matched Mixtures name: … FINAL BULK OF ADSORBED TD VACCINE ... Diphtheria and Tetanus Toxoids Adsorbed ... Tetanus and Diphtheria Toxoids Adsorbed …

Cyanocobalamin

Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched Description: … Several pharmaceutical forms of cyanocobalamin have been developed, including the tablet, injection, ... This vitamin is produced naturally by bacteria [A175276], and is necessary for DNA synthesis and cellular ... and nasal spray forms [FDA label], [L5542], [L5545]. …
Matched Mixtures name: … Harvest Of Values All B Complex Tab ... Herbs of Gold B Complex Plus Softgel ... B Complex W Vit C W Non-med Yeast&liver Tab …
Matched Categories: … Diet, Food, and Nutrition ... Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid ... iron, vitamin B12 and folic acid …

Ixazomib

Ixazomib a second generation proteasome inhibitor (PI) and the first oral PI approved by the FDA in November 2015 for multiple myeloma treatment in combination with 2 other therapies (lenalidomide and dexamethasone) for patients who have received at least 1 prior therapy. It was found to have similar efficacy to...
Approved
Investigational
Matched Description: … myeloma growth and prevention of bone loss. ... similar efficacy to bortezomib (the first PI approved for multiple myeloma therapy) in the control of ... Ixazomib a second generation proteasome inhibitor (PI) and the first oral PI approved by the FDA in November …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Ritonavir

Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors. It is now more commonly used as a...
Approved
Investigational
Matched Description: … American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America ... It is now more commonly used as a booster of other protease inhibitors and is available in both liquid ... Ritonavir is a potent CYP3A inhibitor that increases peak and trough plasma drug concentrations of other …
Matched Mixtures name: … Lopinavir and Ritonavir ... Lopinavir and ritonavir ... Lopinavir and ritonavir …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Antivirals for treatment of HCV infections ... Antivirals used in combination for the treatment of HIV infections ... lopinavir and ritonavir ... darunavir and ritonavir …

Ergometrine

An ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Approved
Matched Description: … An ergot alkaloid with uterine and vascular smooth muscle contractile properties. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones …

Enoxaparin

Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies. Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients...
Approved
Matched Description: … Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various ... Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and ... when compared to unfractionated [heparin], without increasing the risk of serious bleeding. …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …

Dupilumab

Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin ... [A180478] As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory ... atopic or allergic conditions, such as eczema, allergic reaction, and rhinosinusitis. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents …

Rutin

A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Approved
Experimental
Investigational
Matched Mixtures name: … Nutriforte Non-Acidic Vitamin C 1000 mg with Bioflavonoids …

Ceftobiprole medocaril

Ceftobiprole medocaril is a prodrug of ceftobiprole, a fifth-generation semisynthetic cephalosporin antibacterial. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA). The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion...
Approved
Experimental
Investigational
Matched Description: … infections and bacteremia in April 2024. ... Ceftobiprole medocaril is a prodrug of [ceftobiprole], a fifth-generation semisynthetic cephalosporin ... medocaril in February 2010, recommending the refusal of its marketing authorization in the European …

Tremelimumab

Tremelimumab, formerly known as ticilimumab, is a fully human IgG2 monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4). CTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells. By binding to CTLA-4, tremelimumab enhances T cell-mediated killing of tumours...
Approved
Investigational
Matched Description: … [A253717] By binding to CTLA-4, tremelimumab enhances T cell-mediated killing of tumours and reduces ... cell lung cancer (NSCLC), and malignant melanoma. ... [L43652] It is also being investigated in other cancers, such as colon cancer, pancreatic cancer, non-small …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Mometasone furoate

Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well . Mometasone furoate is formulated as a dry powder...
Approved
Investigational
Vet approved
Matched Description: … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and ... Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different ... It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than …
Matched Categories: … formoterol and mometasone …
Matched Products: … Up and Up Allergy ... Nasonex Allergy and Congestion ... Nasal Allergy and Congestion Relief …

Potassium hydroxide

Potassium hydroxide, also known as lye is an inorganic compound with the chemical formula KOH. Also commonly referred to as caustic potash, it is a potent base that is marketed in several forms including pellets, flakes, and powders. It is used in various chemical, industrial and manufacturing applications. Potassium hydroxide...
Approved
Matched Description: … specimens for microscopic visualization of fungi and fungal elements in skin, hair, nails, and even vaginal ... Recently, it has been studied for efficacy and tolerability in the treatment of warts. ... It was determined that topical KOH solution was found to be a safe and effective treatment of plane warts …
Matched Categories: … Indicators and Reagents …

Doravirine

Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). Doravirine is formally indicated for the treatment of...
Approved
Investigational
Matched Description: … no prior antiretroviral treatment experience, further expanding the possibility and choice of therapeutic ... Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered ... lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). …
Matched Categories: … lamivudine, tenofovir disoproxil and doravirine ... Antivirals used in combination for the treatment of HIV infections ... Non-Nucleoside Reverse Transcriptase Inhibitors ... Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor …

Ibritumomab tiuxetan

Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and...
Approved
Investigational
Matched Description: … of 445 amino acids each and two kappa light chains of 213 amino acids each. ... Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains ... normal and malignant B lymphocytes. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Dexketoprofen

Dexketoprofen is a non-steroidal anti-inflammatory drug. It is available in the various countries in Europe, Asia and Latin America. It has analgesic, antipyretic and anti-inflammatory properties .
Approved
Investigational
Matched Description: … Dexketoprofen is a non-steroidal anti-inflammatory drug. ... It has analgesic, antipyretic and anti-inflammatory properties [L1298]. ... It is available in the various countries in Europe, Asia and Latin America. …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Ketoprofen and isomer ... tramadol and dexketoprofen ... Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Antiinflammatory and Antirheumatic Products …

Naxitamab

Naxitamab (humanized 3F8, hu3F8) is an IgG1 monoclonal antibody directed against the oncofetal differentiation antigen GD2 disialoganglioside.[L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and skin cells, GD2 constitutes a highly efficient target in the treatment of neuroblastoma - it is widely expressed across and within...
Approved
Matched Description: … expressed across and within neuroblastomas (and other neuroectodermal tumors),[A224609] and is rarely ... [L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and ... of its predecessor. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Propyliodone

Radiopaque medium usually in oil; used in bronchography.
Approved
Matched Categories: … Diagnostic Uses of Chemicals ... Non-Watersoluble X-Ray Contrast Media …

Fingolimod

Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Matched Description: … neurological, physical, and cognitive effects. ... [L12651] Fingolimod was also studied for the treatment of COVID-19, the disease caused by infection with ... [A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Benzonatate

Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age. Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs...
Approved
Matched Description: … [A189519] It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs and ... Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older ... [A5790] Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. …
Matched Categories: … Non-narcotic Antitussive ... Cough and Cold Preparations …
Displaying drugs 151 - 175 of 14789 in total