Displaying drugs 151 - 175 of 2597 in total
Ertapenem
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl ... -3-carboxylic acid ... (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem …
Matched Iupac: … (4R,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl …
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Matched Products: … ERTAPENEM 1G/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Matched Iupac: … (4R,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl …
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Matched Products: … ERTAPENEM 1G/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Penbutolol
Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Synonyms: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker ... Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric ... Penbutolol is a drug in the beta-blocker class used to treat hypertension. …
Matched Categories: … Antidepressive Agents ... penbutolol and other diuretics ... Adrenergic Agents ... Serotonin Agents ... Hypotensive Agents …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker ... Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric ... Penbutolol is a drug in the beta-blocker class used to treat hypertension. …
Matched Categories: … Antidepressive Agents ... penbutolol and other diuretics ... Adrenergic Agents ... Serotonin Agents ... Hypotensive Agents …
Chlorhexidine
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Description: … [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today. ... Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental ... [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two …
Matched Mixtures name: … 3เอ็ม ซีเอชจี แพด ... KLOROBEN FORT 3 MG/ML+ 2 MG/ML GARGARA, 200 ML ... KLOROBEN FORT 3 MG/ML+ 2 MG/ML ORAL SPREY, 40 ML …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Dental Agents ... Anti-Infective Agents ... Anti-Infective Agents, Local ... Biguanides and Amidines …
Matched Products: … Alsoft A Hand Disinfectant 0.2% w/v ... Foster and Thrive ... 3M AVAGARD 9232 ANTISEPTIC HAND AND BODY WASH CLORHEXIDINE GLUCONATE 2% W/W SOLUTION BOTTE . …
Matched Mixtures name: … 3เอ็ม ซีเอชจี แพด ... KLOROBEN FORT 3 MG/ML+ 2 MG/ML GARGARA, 200 ML ... KLOROBEN FORT 3 MG/ML+ 2 MG/ML ORAL SPREY, 40 ML …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Dental Agents ... Anti-Infective Agents ... Anti-Infective Agents, Local ... Biguanides and Amidines …
Matched Products: … Alsoft A Hand Disinfectant 0.2% w/v ... Foster and Thrive ... 3M AVAGARD 9232 ANTISEPTIC HAND AND BODY WASH CLORHEXIDINE GLUCONATE 2% W/W SOLUTION BOTTE . …
Fenoprofen
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Matched Synonyms: … 3-phenoxyhydratropic acid ... 2-(3-phenoxyphenyl)propionic acid ... (±)-2-(3-phenoxyphenyl)propionic acid …
Matched Iupac: … 2-(3-phenoxyphenyl)propanoic acid …
Matched Description: … An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Nephrotoxic agents ... Antirheumatic Agents ... Agents causing hyperkalemia …
Matched Iupac: … 2-(3-phenoxyphenyl)propanoic acid …
Matched Description: … An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Nephrotoxic agents ... Antirheumatic Agents ... Agents causing hyperkalemia …
Cholestyramine
Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.
Approved
Investigational
Matched Description: … Cholestyramine or colestyramine is a bile acid sequestrant. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Anticholesteremic Agents ... Hypolipidemic Agents ... Lipid Modifying Agents ... Lipid Regulating Agents …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Anticholesteremic Agents ... Hypolipidemic Agents ... Lipid Modifying Agents ... Lipid Regulating Agents …
Fenofibric acid
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Description: … Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia ... , and mixed dyslipidemia. ... for improved solubility, gastrointestinal absorption, and bioavailability, and more convenient administration …
Matched Categories: … Anticholesteremic Agents ... Hypolipidemic Agents ... Lipid Modifying Agents ... Agents Causing Muscle Toxicity ... Lipid Regulating Agents …
Matched Categories: … Anticholesteremic Agents ... Hypolipidemic Agents ... Lipid Modifying Agents ... Agents Causing Muscle Toxicity ... Lipid Regulating Agents …
Acrivastine
Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and tachycardia.
Acrivastine is...
Approved
Matched Synonyms: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acid …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and …
Matched Categories: … Histamine Agents ... QTc Prolonging Agents ... Neurotransmitter Agents ... Potential QTc-Prolonging Agents …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and …
Matched Categories: … Histamine Agents ... QTc Prolonging Agents ... Neurotransmitter Agents ... Potential QTc-Prolonging Agents …
Capsaicin
Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent...
Approved
Matched Iupac: … (6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide …
Matched Description: … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, ... and patch preparations of various strengths; however, it may also be found in some dietary supplements ... Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical …
Matched Mixtures name: … Med O-3 Bio- ... Satohap Cool and Hot Pads ... Zostrix Hot and Cold Therapy System …
Matched Categories: … Capsaicin and Similar Agents ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Basic Lotions and Liniments ... Sensory System Agents ... Peripheral Nervous System Agents …
Matched Products: … Omega 3 ... Omega 3 Heat Therapy ... Antiphlogistine Rub A-535 Capsaicin Gel …
Matched Description: … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, ... and patch preparations of various strengths; however, it may also be found in some dietary supplements ... Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical …
Matched Mixtures name: … Med O-3 Bio- ... Satohap Cool and Hot Pads ... Zostrix Hot and Cold Therapy System …
Matched Categories: … Capsaicin and Similar Agents ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Basic Lotions and Liniments ... Sensory System Agents ... Peripheral Nervous System Agents …
Matched Products: … Omega 3 ... Omega 3 Heat Therapy ... Antiphlogistine Rub A-535 Capsaicin Gel …
Homatropine
Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated for the symptomatic relief of cough as oral tablets or solutions. Homatropine is included in subtherapeutic amounts as homatropine...
Approved
Matched Iupac: … (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate …
Matched Description: … Homatropine hydrobromide has been administered as ophthalmic solutions as a cycloplegic to temporarily ... use has not been approved by the FDA to be safe and effective. ... paralyze accomodation, and to induce mydriasis (the dilation of the pupil); however such therapeutic …
Matched Categories: … Mydriatics and Cycloplegics ... Autonomic Agents ... Anticholinergic Agents ... Peripheral Nervous System Agents …
Matched Description: … Homatropine hydrobromide has been administered as ophthalmic solutions as a cycloplegic to temporarily ... use has not been approved by the FDA to be safe and effective. ... paralyze accomodation, and to induce mydriasis (the dilation of the pupil); however such therapeutic …
Matched Categories: … Mydriatics and Cycloplegics ... Autonomic Agents ... Anticholinergic Agents ... Peripheral Nervous System Agents …
Gilteritinib
Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group. It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit -driven myelosuppression observed in other...
Approved
Investigational
Matched Iupac: … 6-ethyl-3-({3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-[(oxan-4-yl)amino]pyrazine …
Matched Description: … that presented a greater selectivity and potency when compared with other agents from this group. ... This drug was approved after being designed as an orphan drug with a fast track and priority review status ... [A40044] Gilteritinib was developed by Astellas Pharma and FDA approved on November 28, 2018. …
Matched Salts cas: … 1254053-84-3 …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... fms-Like Tyrosine Kinase 3, antagonists & inhibitors ... Antineoplastic Agents ... QTc Prolonging Agents ... Moderate Risk QTc-Prolonging Agents …
Matched Description: … that presented a greater selectivity and potency when compared with other agents from this group. ... This drug was approved after being designed as an orphan drug with a fast track and priority review status ... [A40044] Gilteritinib was developed by Astellas Pharma and FDA approved on November 28, 2018. …
Matched Salts cas: … 1254053-84-3 …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... fms-Like Tyrosine Kinase 3, antagonists & inhibitors ... Antineoplastic Agents ... QTc Prolonging Agents ... Moderate Risk QTc-Prolonging Agents …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A ... O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->4)-O-(6-AMINO-6-DEOXY-.ALPHA. ... D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA. …
Matched Iupac: … 6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3- …
Matched Description: … Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group ... M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. ... Symptoms of this disease include a persistent cough, fatigue, weight loss, night sweats, and shortness …
Matched Categories: … cefepime and amikacin ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index ... Anti-Bacterial Agents ... Anti-Infective Agents ... Nephrotoxic agents …
Matched Iupac: … 6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3- …
Matched Description: … Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group ... M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. ... Symptoms of this disease include a persistent cough, fatigue, weight loss, night sweats, and shortness …
Matched Categories: … cefepime and amikacin ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index ... Anti-Bacterial Agents ... Anti-Infective Agents ... Nephrotoxic agents …
Masoprocol
A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem]
Approved
Investigational
Matched Description: … a lesser extent. ... It also serves as an antioxidant in fats and oils. [PubChem] ... A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Compounds used in a research, industrial, or household setting ... Antineoplastic Agents ... Protective Agents ... Anti-Inflammatory Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Compounds used in a research, industrial, or household setting ... Antineoplastic Agents ... Protective Agents ... Anti-Inflammatory Agents …
Imatinib
Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with...
Approved
Matched Synonyms: … α-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidide …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …
Matched Description: … The discovery of imatinib also established a new group of therapy called "targeted therapy", since treatment ... daily dosage of 300 mg or more and typically occurred in the first four weeks of therapy". ... [L42220] Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives ... Antineoplastic Agents ... QTc Prolonging Agents ... Myelosuppressive Agents …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …
Matched Description: … The discovery of imatinib also established a new group of therapy called "targeted therapy", since treatment ... daily dosage of 300 mg or more and typically occurred in the first four weeks of therapy". ... [L42220] Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives ... Antineoplastic Agents ... QTc Prolonging Agents ... Myelosuppressive Agents …
Torasemide
Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Synonyms: … 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea ... N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Description: … Torasemide is a high-ceiling loop diuretic. ... [A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. …
Matched Categories: … Antihypertensive Agents ... Ototoxic agents ... Cardiovascular Agents ... Hypotensive Agents ... Natriuretic Agents …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Description: … Torasemide is a high-ceiling loop diuretic. ... [A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. …
Matched Categories: … Antihypertensive Agents ... Ototoxic agents ... Cardiovascular Agents ... Hypotensive Agents ... Natriuretic Agents …
Eprosartan
Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Synonyms: … (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid …
Matched Description: … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs …
Matched Salts cas: … 197855-71-3 …
Matched Categories: … eprosartan and diuretics ... Angiotensin II receptor blockers (ARBs) and diuretics ... Hypotensive Agents ... Agents causing angioedema ... Cardiovascular Agents …
Matched Description: … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs …
Matched Salts cas: … 197855-71-3 …
Matched Categories: … eprosartan and diuretics ... Angiotensin II receptor blockers (ARBs) and diuretics ... Hypotensive Agents ... Agents causing angioedema ... Cardiovascular Agents …
Difenoxin
Difenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. Difenoxin alone is a USA Schedule I controlled drug, as it may be habit forming. However, it is listed as a Schedule IV controlled drug if combined with atropine, which is added to decrease deliberate misuse. Motofen(R)...
Approved
Illicit
Matched Synonyms: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid …
Matched Iupac: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid …
Matched Description: … Motofen(R) is a brand mixture which combines atropine sulfate and difenoxin hydrochloride. ... nervous system (CNS). [3] Difenoxin is also closely related to loperamide, but unlike loperamide it ... It is approved by the FDA to treat acute and chronic diarrhea. …
Matched Categories: … Alimentary Tract and Metabolism ... Antidiarrheals, Intestinal Antiinflammatory/antiinfective Agents …
Matched Iupac: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid …
Matched Description: … Motofen(R) is a brand mixture which combines atropine sulfate and difenoxin hydrochloride. ... nervous system (CNS). [3] Difenoxin is also closely related to loperamide, but unlike loperamide it ... It is approved by the FDA to treat acute and chronic diarrhea. …
Matched Categories: … Alimentary Tract and Metabolism ... Antidiarrheals, Intestinal Antiinflammatory/antiinfective Agents …
Difluprednate
Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate. It is indicated for treatment of endogenous anterior uveiti.
Approved
Matched Iupac: … 5,9b-difluoro-10-hydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated ... It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. …
Matched Categories: … Immunosuppressive Agents ... Corticosteroids, Potent (Group III) ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated ... It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. …
Matched Categories: … Immunosuppressive Agents ... Corticosteroids, Potent (Group III) ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Estrone sulfate
Estrone sulfate (as estropipate) is a form of estrogen. It has several uses such as: alleviate symptoms of menopause as hormone replacement therapy, treatment some types of infertility, treatment of some conditions leading to underdevelopment of female sexual characteristics, treatment of vaginal atrophy, treatment of some types of breast cancer...
Approved
Matched Synonyms: … Estrone 3-sulfate ... Estrone-3-sulphate ... Estra-1,3,5 (10)-triene-17-one-3-yl-sulfate …
Matched Iupac: … [(3aS,3bR,9bS,11aS)-11a-methyl-1-oxo-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren …
Matched Description: … Estrone sulfate (as estropipate) is a form of estrogen. ... postmenopausal women), treatment of prostate cancer and prevention of osteoporosis. ... characteristics, treatment of vaginal atrophy, treatment of some types of breast cancer (particularly in men and …
Matched Mixtures name: … Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Contraceptive Agents, Hormonal ... Reproductive Control Agents ... Hyperglycemia-Associated Agents …
Matched Iupac: … [(3aS,3bR,9bS,11aS)-11a-methyl-1-oxo-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren …
Matched Description: … Estrone sulfate (as estropipate) is a form of estrogen. ... postmenopausal women), treatment of prostate cancer and prevention of osteoporosis. ... characteristics, treatment of vaginal atrophy, treatment of some types of breast cancer (particularly in men and …
Matched Mixtures name: … Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Contraceptive Agents, Hormonal ... Reproductive Control Agents ... Hyperglycemia-Associated Agents …
Etacrynic acid
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop...
Approved
Investigational
Matched Description: … A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of ... This compound has been classified as a loop or high ceiling diuretic. ... Henle, but also in the proximal and distal tubules. …
Matched Categories: … Ototoxic agents ... Hypotensive Agents ... Natriuretic Agents ... Nephrotoxic agents ... Hyperglycemia-Associated Agents …
Matched Categories: … Ototoxic agents ... Hypotensive Agents ... Natriuretic Agents ... Nephrotoxic agents ... Hyperglycemia-Associated Agents …
Trypan blue free acid
Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.
Approved
Matched Iupac: … 5-amino-3-[(E)-2-{4'-[(E)-2-(8-amino-1-hydroxy-3,6-disulfonaphthalen-2-yl)diazen-1-yl]-3,3'-dimethyl- …
Matched Description: … of a mature cataract. ... Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence …
Matched Categories: … Coloring Agents ... Compounds used in a research, industrial, or household setting …
Matched Description: … of a mature cataract. ... Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence …
Matched Categories: … Coloring Agents ... Compounds used in a research, industrial, or household setting …
Zaleplon
Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.
Approved
Illicit
Investigational
Matched Synonyms: … 3'-(3-Cyanopyrazolo(1,5-a)pyrimidin-7-yl)-N-ethylacetanilide …
Matched Iupac: … N-(3-{3-cyanopyrazolo[1,5-a]pyrimidin-7-yl}phenyl)-N-ethylacetamide …
Matched Description: … Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of ... It is known as a nonbenzodiazepine hypnotic. ... Zaleplon is a sedative/hypnotic, mainly used for insomnia. …
Matched Categories: … GABA-A Receptor Agonists ... GABA Agents ... gamma-Aminobutyric Acid A Receptor Agonist ... Hypnotics and Sedatives ... Neurotransmitter Agents …
Matched Iupac: … N-(3-{3-cyanopyrazolo[1,5-a]pyrimidin-7-yl}phenyl)-N-ethylacetamide …
Matched Description: … Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of ... It is known as a nonbenzodiazepine hypnotic. ... Zaleplon is a sedative/hypnotic, mainly used for insomnia. …
Matched Categories: … GABA-A Receptor Agonists ... GABA Agents ... gamma-Aminobutyric Acid A Receptor Agonist ... Hypnotics and Sedatives ... Neurotransmitter Agents …
Lovastatin
Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid...
Approved
Investigational
Matched Description: … event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular events ... stroke, has become a leading cause of death in high-income countries and a major cause of morbidity ... Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite …
Matched Categories: … lovastatin and nicotinic acid ... Anticholesteremic Agents ... Hypolipidemic Agents ... Agents Causing Muscle Toxicity ... Lipid Modifying Agents …
Matched Categories: … lovastatin and nicotinic acid ... Anticholesteremic Agents ... Hypolipidemic Agents ... Agents Causing Muscle Toxicity ... Lipid Modifying Agents …
Lumiracoxib
Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver failure. New Zealand and Canada have also followed suit in recalling...
Approved
Investigational
Matched Description: … New Zealand and Canada have also followed suit in recalling the drug. ... Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Nephrotoxic agents ... Antirheumatic Agents ... Agents causing hyperkalemia …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Nephrotoxic agents ... Antirheumatic Agents ... Agents causing hyperkalemia …
Carbenicillin
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Citric acid
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability.
Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … 3-carboxy-3-hydroxypentane-1,5-dioic acid …
Matched Description: … A key intermediate in metabolism. It is an acid compound found in citrus fruits. ... Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved …
Matched Mixtures name: … Acd-A ... Anticoagulant Citrate Dextrose A ACD-A ... Acd A …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting ... Chelating Agents ... Hematologic Agents ... Sequestering Agents …
Matched Description: … A key intermediate in metabolism. It is an acid compound found in citrus fruits. ... Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved …
Matched Mixtures name: … Acd-A ... Anticoagulant Citrate Dextrose A ACD-A ... Acd A …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting ... Chelating Agents ... Hematologic Agents ... Sequestering Agents …
Displaying drugs 151 - 175 of 2597 in total