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Displaying drugs 151 - 175 of 10294 in total

Amifostine

A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Approved
Investigational
Matched Categories: … Hypotensive Agents ... Protective Agents ... Radiation-Protective Agents ... Detoxifying Agents for Antineoplastic Treatment …

Anidulafungin

Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366. There is preliminary evidence that it has a similar safety profile to caspofungin.
Approved
Investigational
Matched Description: … Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food …
Matched Categories: … Antifungal Agents ... Anti-Infective Agents …

Trimebutine

Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI...
Approved
Matched Description: … Trimebutine is not a FDA-approved drug, but it is available in Canada and several other international …
Matched Categories: … Synthetic Anticholinergics, Esters With Tertiary Amino Group ... Autonomic Agents ... Antiarrhythmic agents ... Prokinetic Agents ... Anticholinergic Agents …

Cobicistat

Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Description: … cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents ... exposure of atazanavir or darunavir (once daily dosing regimen) in combination with other antiretroviral agents …
Matched Categories: … Anti-HIV Agents ... Anti-Infective Agents ... Other Miscellaneous Therapeutic Agents …

Etravirine

Etravirine is an antiretroviral agent more specifically classified as a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI). Etraverine is used clinically for the treatment of human immunodeficiency virus type 1 (HIV-1) infection. On January 18, 2007, the FDA granted accelerated approved for the use of etravirine 100mg tablets in the treatment of...
Approved
Matched Description: … Etravirine is an antiretroviral agent more specifically classified as a Non-Nucleoside Reverse Transcriptase ... On January 18, 2007, the FDA granted accelerated approved for the use of etravirine 100mg tablets in ... of adult HIV-1 infection documented to be resistant to therapy with other NNRTIs and antiretroviral agents …
Matched Categories: … Antiviral Agents ... Anti-Infective Agents ... Anti-Retroviral Agents …

Homatropine methylbromide

Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be...
Approved
Matched Description: … methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group …
Matched Categories: … Anticholinergic Agents ... Agents producing tachycardia …

Testosterone propionate

Testosterone propionate is a slower-releasing anabolic steroid with a short half-life. It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of testosterone. Testosterone propionate was developed initially by Watson labs, and FDA approved on February 5, 1974. Currently, this drug has been discontinued...
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … [T83] Testosterone propionate was developed initially by Watson labs, and FDA approved on February 5, ... Currently, this drug has been discontinued in humans, but the vet application is still available as an …

Benzocaine

Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve …
Matched Categories: … Sensory System Agents ... Central Nervous System Agents ... Peripheral Nervous System Agents ... Methemoglobinemia Associated Agents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Alprostadil

Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Description: … In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection ... or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for …
Matched Categories: … Cardiovascular Agents ... Hematologic Agents ... Urological Agents ... Genitourinary Agents ... Vasodilating Agents …

Calcium threonate

Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement . It is found in dietary supplements as a source of L-threonate used in the treatment of calcium deficiency and prevention of osteoporosis. The most common...
Approved
Matched Description: … L-threonate is an active metabolite of vitamin C that mediates a stimulatory action on vitamin C uptake …

Benzoin

Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide, and is used in organic syntheses. This should not be confused with benzoin gum from STYRAX (see DB11222). Benzoin is an FDA-approved colour additive used for marking fruits and vegetables.
Approved
Experimental
Matched Description: … Benzoin is an FDA-approved colour additive used for marking fruits and vegetables. …
Matched Categories: … Anti-Infective Agents, Local …

Iodoform

Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. It is a relatively water-insoluble yellow solid that is chemically reactive in free-radical reactions . Due to its antimicrobial properties following topical administration, minimal levels of iodoform may be found in disinfectants and it is more...
Approved
Experimental
Vet approved
Matched Description: … Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. …

Honey

Honey is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Honey is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug. …

Molindone

An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate...
Approved
Matched Description: … An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment ... Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively …
Matched Categories: … Antidepressive Agents ... Antipsychotic Agents ... Neurotoxic agents ... Serotonin Agents ... Tranquilizing Agents …

Adenosine

The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … [A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[ …
Matched Categories: … Antiarrhythmic agents ... Purinergic Agents ... Cardiovascular Agents ... Vasodilating Agents ... Agents producing tachycardia …
Matched Products: … An Adc Sp F …

Aluminum chlorohydrate

Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near...
Approved
Matched Description: … Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl( ... It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. …

Spironolactone

Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … [A178135, A261025] Spironolactone was developed in 1957, marketed in 1959, and approved by the FDA …
Matched Categories: … Antihypertensive Agents ... Cardiovascular Agents ... Hypotensive Agents ... Natriuretic Agents ... Agents causing hyperkalemia …

Aluminum sulfate

Aluminum (Al), also spelled aluminum, chemical element, a lightweight, silvery-white metal of main Group 13 (IIIa, or boron group) of the periodic table . It is a chemical agent used in water purification, the pH regulation of garden soil, and other commercial or industrial applications. Medically, it is primarily used...
Approved
Matched Description: … 13 (IIIa, or boron group) of the periodic table [L2148]. ... Aluminum (Al), also spelled aluminum, chemical element, a lightweight, silvery-white metal of main Group …

Metformin

Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval ... [L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and …
Matched Categories: … Blood Glucose Lowering Agents …
Matched Products: … METFORMINA EG STADA GROUP …

Ferric carboxymaltose

Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.
Approved
Matched Description: … It was FDA approved on July 25, 2013. ... Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. …

Lovotibeglogene autotemcel

Lovotibeglogene autotemcel consists of autologous hematopoietic stem and progenitor cells transduced with the BB305 lentiviral vector encoding a modified β-globin gene. Specifically, lovotibeglogene autotemcel provides a functional copy of a modified beta-globin gene (βA-T87Q-globin) that when combined with α-globin, produces hemoglobins with similar oxygen-binding capacity as wild type hemoglobin. Additionally,...
Approved
Investigational
Matched Description: … [A262736,L49256] On December 8, 2023, lovotibeglogene autotemcel was approved by the FDA under the ... [L49266] It was approved alongside [exagamglogene autotemcel] (Casgevy), another gene therapy, with the ... comprising the first cell-based gene therapies for the treatment of SCD in patients 12 years and older to be approved …

Tedizolid phosphate

Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Description: … This product is currently available as both an oral tablet and as a powder for intravenous injection. ... [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist ... A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved …
Matched Categories: … Antidepressive Agents ... Anti-Bacterial Agents ... Anti-Infective Agents ... Serotonin Agents ... Immunosuppressive Agents …

Rifabutin

A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
Approved
Investigational
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …

Anisindione

Anisindione is a synthetic anticoagulant and an indanedione derivative. Its anticoagulant action is mediated through the inhibition of the vitamin K-mediated gamma-carboxylation of precursor proteins that are critical in forming the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S,...
Approved
Matched Description: … Anisindione is a synthetic anticoagulant and an indanedione derivative. …

Anthoxanthum odoratum

Anthoxanthum odoratum allergenic extract is used in allergenic testing.
Approved
Displaying drugs 151 - 175 of 10294 in total