Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 176 - 200 of 13643 in total

Obeticholic acid

Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Iupac: … 3aS,3bS,4R,5R,5aS,7R,9aS,9bS,11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … to be granted full approval for this indication in 2020. ... hepatic decompensation) due to a risk of liver failure, in some cases requiring liver transplantation ... allowing for increased survival. …

Potassium hydroxide

Potassium hydroxide, also known as lye is an inorganic compound with the chemical formula KOH. Also commonly referred to as caustic potash, it is a potent base that is marketed in several forms including pellets, flakes, and powders. It is used in various chemical, industrial and manufacturing applications. Potassium hydroxide...
Approved
Matched Description: … Recently, it has been studied for efficacy and tolerability in the treatment of warts. ... specimens for microscopic visualization of fungi and fungal elements in skin, hair, nails, and even vaginal ... Potassium hydroxide is used in food to adjust pH, as a stabilizer, and as a thickening agent. …
Matched Mixtures name: … Nutriflex Peri Solution for Infusion ... NUTRIFLEX PERI IN 2000ML TWIN-FLEX ... NUTRIFLEX PLUS IN 1000ML TWIN FLEX …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MIRACLE WATER 3 in 1 …

Amifostine

A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Approved
Investigational
Matched Description: … A phosphorothioate proposed as a radiation-protective agent. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Detoxifying Agents for Antineoplastic Treatment …

Pralidoxime

Pralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. If given within 24 hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase.
Approved
Vet approved
Matched Description: … Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … PAM-A INJECTION 500 mg/ampoule …

Sildenafil

In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Description: … and effective treatment for erectile dysfunction and since its formal approval for medical use in the ... being serendipitously indicated for treating erectile dysfunction in the late 1980s [A175732]. ... public in 1998 [A175732], continues to see millions of prescriptions written for it internationally. …
Matched Categories: … Drugs Used in Erectile Dysfunction …
Matched Products: … Sildenafil for Oral Suspension ... A-Sildenafil Tablets 100mg …

Secukinumab

Secukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque psoriasis. By blocking the actions of IL-17A, secukinumab works to inhibit the pro-inflammatory pathways that drive immune-mediated inflammatory disorders. Following its first global approval in Japan...
Approved
Matched Description: … [A249840] Following its first global approval in Japan in December 2014, secukinumab was approved by ... Secukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory ... cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque psoriasis …
Matched Categories: … Agents reducing cytokine levels …
Matched Products: … Cosentyx 150mg/ml solution for injection in pre-filled syringe ... COSENTYX SOLUTION FOR INJECTION IN PREFILLED SYRINGE 150MG/ML ... Fraizeron 150mg/ml solution for injection in pre-filled pen …

Ferumoxytol

Ferumoxytol is an intravenously administered iron preparation indicated in the EU and the US for the treatment of iron deficiency anemia in adult patients with chronic kidney disease (CKD) . It is comprised of superparamagnetic iron oxide nanoparticles which are coated by a semi-synthetic carbohydrate shell in an isotonic, neutral...
Approved
Investigational
Matched Description: … Ferumoxytol is an intravenously administered iron preparation indicated in the EU and the US for the ... It is comprised of superparamagnetic iron oxide nanoparticles which are coated by a semi-synthetic carbohydrate ... treatment of iron deficiency anemia in adult patients with chronic kidney disease (CKD) [A32478]. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Trimethoprim

Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Description: … and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of urinary ... Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a ... critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents …
Matched Mixtures name: … Hampiseptol Solution For Injection ... Sulfamethoxazole and Trimethoprim for Injection, USP ... Sulfamethoxazole and Trimethoprim for Injection, USP …
Matched Categories: … Medications that reduce magnesium levels ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Antibiotics for Pneumocystis Pneumonia …

Water

Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds. Water is a...
Approved
Matched Description: … As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected ... Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and ... Water is a liquid at standard ambient temperature and pressure, but it often co-exists on Earth with …
Matched Mixtures name: … Intron A ... Intron A ... Instillation Medium for Immucyst …
Matched Products: … N/A ... A-Med ... A-Med brand First Aid Eye and Skin-Rinse …

Pyrithione

Pyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers. In the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat...
Approved
Matched Description: … In the crystalline state, it exists as a centrosymmetric dimer. ... pyrithione zinc has been reported for decades. ... It mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters …
Matched Mixtures name: … ReEn Mogangbichaek for Sensitive Scalp ... ReEn Hairloss Clinic Jahajin Shampoo for Sensitive Scalp …
Matched Products: … Head & Shoulders Total Care All-IN-1 Men ... Head and Shoulders Men Total Care All in 1 ... Classic Clean 2 In 1 for Normal Hair …

Triptorelin

Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Description: … Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. ... Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH) ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Products: … Triptofem 0,1 mg/ml Injektionslösung in einer Fertigspritze ... Decapeptyl Depot - Retardmikrokapseln und Suspensionsmittel in Einmalspritzen ... Pamorelin Powder for Suspension for Injection 3.75 mg …

Coenzyme M

Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Synonyms: … CoM ... HS-CoM ... reduced CoM …
Matched Description: … used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis. ... Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Detoxifying Agents for Antineoplastic Treatment …
Matched Products: … Mesna for Injection ... CONCENTRATE SOLUTION FOR INJECTION 400MG/4ML …

Potassium nitrate

Potassium nitrate is an inorganic salt with a chemical formula of KNO3. It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. Potassium nitrate is a common active ingredient in toothpaste,...
Approved
Matched Description: … It is a natural source of nitrate and has been used as a constituent for several different purposes, ... In addition, potassium nitrate is used as a diuretic in pigs, cattle, and horses. ... Potassium nitrate is a common active ingredient in toothpaste, exerting an anti-sensitivity action. …
Matched Mixtures name: … Unidental All CareToothpaste ... Spotlight Oral Care for Sensitive Teeth ... Spotlight Oral Care for Rebuilding Teeth …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Theophylline

A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly...
Approved
Matched Description: … Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for ... A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac ... Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and …
Matched Mixtures name: … TUSBRON-A JARABE ... Theophylline in Dextrose ... Theophylline in Dextrose …
Matched Categories: … Drugs for Obstructive Airway Diseases ... Medications that reduce magnesium levels ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … Theophylline in Dextrose …

Cetylpyridinium

Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.
Approved
Matched Description: … Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. ... In these products, it generally mediates an antiseptic activity and protective action against dental ... Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes …
Matched Mixtures name: … Kank-A ... Unidental All CareToothpaste …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Scope All Day CPC Antigingivitis/Antiplaque Mouthwash All Day ... Crest Pro-Health For Life ... Orajle Anti-Bacterial Rinse for Bleeding Gums …

Nitric Oxide

Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power...
Approved
Matched Description: … important intermediate in the chemical industry. ... This gas is an important signaling molecule in the body of mammals including humans and is an extremely ... Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … GNO Refreshing Mist (For skin care, and dry skin, safe to use it in the eye, Acne treatment, Fermented ... GNO All-in-One Cleanser (Prevents hairloss, Fermented lettuce, garlic, bean, cabbage, cricket Greentea ... GNO All-in-One Cleanser (Prevents hairloss, Fermented lettuce, garlic, bean, cabbage, cricket Greentea …

Icatibant

Icatibant is a synthetic decapeptide with 5 nonproteinogenic amino acid antagonist targeting the B2 receptors with a similar affinity to bradykinin. It is resistant to bradykinin-cleaving enzyme degradation and has a potency of 2-3 times higher than earlier B2 receptors antagonists, thus representing a new class of medication.[A4017,A263041] It was...
Approved
Investigational
Matched Description: … [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a ... treatment for hereditary angioedema. ... median time to almost complete symptom relief was observed to be 8 hours compared to 36 hours for the …
Matched Categories: … Drugs Used in Hereditary Angioedema …
Matched Products: … Icatibant STADA 30 mg Injektionslösung in einer Fertigspritze ... Icatibant Hikma 30 mg Injektionslösung in einer Fertigspritze ... Icatibant ratiopharm 30 mg Injektionslösung in einer Fertigspritze …

Chromium

Chromium is a transition element with the chemical symbol Cr and atomic number 24 that belongs to Group 6 of the periodic table. It is used in various chemical, industrial and manufacturing applications such as wood preservation and metallurgy. The uses of chromium compounds depend on the valency of chromium,...
Approved
Matched Description: … Chromium chloride is available as an intravenous injection for use as a supplement to intravenous solutions ... 2 diabetes mellitus (T2DM) to improve blood sugar metabolism and stabilize the levels of serum cholesterol ... given for total parenteral nutrition (TPN) [FDA Label]. …
Matched Mixtures name: … For-2 ... Extra Once A Day ... Once A Day Tablets …
Matched Products: … Slm3.com …

Pralatrexate

Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Description: … [A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein ... for their B-cells counterparts. ... that is overexpressed in malignant cells and is upregulated by oncogenes. …
Matched Products: … SOLUTION FOR INFUSION 20MG/ML ... Folotyn 20mg/ml Solution for Infusion …

Octisalate

Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other...
Approved
Investigational
Matched Description: … Octyl salicylate is used to augment the UVB protection in a sunscreen. ... Octyl salicylate appears to have a good safety profile. ... It covers wavelength in the range 295-315 nm, peak at 307-310 nm. …
Matched Mixtures name: … Hope In A Jar Broad Spectrum SPF 25 Sunscreen and Moisturizer for All Skin Types ... Hope In A Jar SPF 25 ... Gloves in a Bottle with SPF15 …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Rurioctocog alfa pegol

Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … [A245139] Rurioctocog alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia ... Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …

Chromic chloride

Chromic chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Matched Description: … Chromic chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive ... to solutions for Total Parenteral Nutrition (TPN). …
Matched Mixtures name: … One-A-day Advance Men's ... Addaven Concentrate for Solution for Infusion ... ADDAVEN CONCENTRATE FOR SOLUTION FOR INFUSION …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Lipoic acid

A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Description: … A vitamin-like antioxidant. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … A-LIPOR® ... NUTRABIOTICS A-LIPOR ® ACIDO ALFA LIPOICO ... A-LIPOR P.O® 600 MG TABLETAS RECUBIERTAS …

Dipotassium phosphate

Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Approved
Matched Description: … as a source of phosphorus and potassium as well as a buffering agent. ... Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive …
Matched Mixtures name: … Instillation Medium for Immucyst ... Isolyte M in Dextrose ... Isolyte P in Dextrose …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Loperamide

Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Description: … [A251610, A251625] However, loperamide is associated with a risk for experiencing a range of adverse ... [L42785] The drug was first synthesized in 1969 and used medically in 1976. ... Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating …
Matched Mixtures name: … Doc in the Box All Day Supply …
Matched Products: … A D ... Imodium A-D ... Vaprino A-D …
Displaying drugs 176 - 200 of 13643 in total