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Displaying drugs 26 - 50 of 1699 in total

Brigatinib

Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type. It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a...
Approved
Investigational
Matched Description: … Ariad Pharmaceuticals, a subsidiary of Takeda Pharmaceutical Company Limited, and FDA-approved on April 28 …
Matched Products: … ALUNBRİG 30 MG FİLM KAPLI TABLET, 28 ADET ... ALUNBRİG 90 MG FİLM KAPLI TABLET, 28 ADET ... ALUNBRİG 180 MG FİLM KAPLI TABLET, 28 ADET …

Drospirenone

Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Iupac: … (1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.0^{2,4}.0^{5,10}.0^{14,19} ... .0^{16,18}]nonadecane-15,2'-oxolan]-5-ene-5',7-dione …
Matched Mixtures name: … Zarah 28 ... Yasmin 28 ... Zamine 28 …
Matched Products: … ZLYNDA 4 MG FİLM KAPLI TABLET, 28 ADET …

Zafirlukast

Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Products: … CARROX 10 MG FILM TABLET, 28 TABLET ... CARROX 20 MG FILM TABLET, 28 TABLET …

Abemaciclib

Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for...
Approved
Investigational
Matched Description: … On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for …
Matched Products: … YULAREB 50 MG FİLM KAPLI TABLET, 28 ADET ... YULAREB 150 MG FİLM KAPLI TABLET, 28 ADET ... YULAREB 100 MG FİLM KAPLI TABLET, 28 ADET …

Dabrafenib

Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. It was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation. It was also used for metastatic non-small cell lung cancer with the same mutation. In May 2018, Tafinlar (dabrafenib),...
Approved
Investigational
Matched Products: … TAFINLAR 50 MG KAPSÜL ,28 ADET ... TAFINLAR 75 MG KAPSÜL, 28 ADET …

Nilotinib

Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic benefits in cases of CML which were found to be resistant...
Approved
Investigational
Matched Products: … TASIGNA 150 MG KAPSUL, 28 ADET ... TASIGNA 200 MG KAPSUL, 28 ADET …

Sodium zirconium cyclosilicate

Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Products: … SIMKELMA 5 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 28 ADET ... SIMKELMA 10 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 28 ADET …

Saxagliptin

Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Approved
Matched Mixtures name: … QTERN 5 MG/10 MG FİLM KAPLI TABLET, 28 ADET …
Matched Products: … ONGLYZA 5 MG FILM KAPLI TABLET, 28 ADET ... ONGLYZA 2.5 MG FILM KAPLI TABLET, 28 ADET …

Alogliptin

Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Products: … VIPIDIA 25 MG FILM KAPLI TABLET,28 ADET ... VIPIDIA 12.5 MG FILM KAPLI TABLET, 28 ADET …

Tioconazole

Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Products: … TROSYD SOLUCION PARA UÑAS 28% ... DERMO-TROSYD %28 SOLUSYON, 5 ML ... TIOCELL %28 TIRNAK SOLUSYONU, 5 CC …

Sofosbuvir

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Mixtures name: … HARVONI 90 MG/400 MG FILM KAPLI TABLET, 28 ADET ... VOSEVİ 400 MG/ 100 MG/ 100 MG FİLM KAPLI TABLET, 28 ADET …
Matched Products: … SOVALDI 400 MG FILM KAPLI TABLET, 28 ADET …

Brexucabtagene autoleucel

Mantle cell lymphoma is a heterogeneous sub-category of non-Hodgkin's lymphoma that can be classified as either an aggressive nodal or an indolent leukemic non-nodal variant. Despite the introduction of Bruton's tyrosine kinase (BTK) inhibitors such as ibrutinib and acalabrutinib, the prognosis for MCL patients remains poor and those that relapse...
Approved

Niacin

Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.[L7550,L7553,L7556,L7559,L7562,L7565]
Approved
Investigational
Nutraceutical
Matched Products: … TABLET, 28 ADET ... TABLET, 28 ADET ... NIASCOR 750 MG 28 E.R. UZATILMIS SALIMLI TABLET …

Febuxostat

Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Products: … FEBUGUT 80 MG FİLM KAPLI TABLET, 28 ADET ... GUSTAT 80 MG FİLM KAPLI TABLET, 28 ADET ... GUSTAT 120 MG FİLM KAPLI TABLET, 28 ADET …

Moxonidine

Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Products: … PHYSIOTENS 0,3 MG FILM KAPLI TABLET, 28 ADET ... PHYSIOTENS 0,2 MG FİLM KAPLI TABLET, 28 ADET ... PHYSIOTENS 0,4 MG FILM KAPLI TABLET, 28 ADET …

Simeprevir

Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United...
Approved
Matched Products: … OLYSIO 150 MG KAPSUL ,KAPSUL, 28 ADET …

Finasteride

Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). It works in a similar fashion as dutasteride, which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. Finasteride is an orally active drug...
Approved
Matched Products: … PROSCAR 5 MG FILM TABLET, 28 ADET ... ALOFİN 1 MG FİLM KAPLI TABLET, 28 ADET ... PROSCAR 5 MG FİLM KAPLI TABLET, 28 ADET …

Baricitinib

Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Products: … UNAMİTY 4 MG FİLM KAPLI TABLET, 28 ADET ... UNAMİTY 2 MG FİLM KAPLI TABLET, 28 ADET …

Eprosartan

Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Mixtures name: … TEVETEN PLUS 600/12.5 MG FİLM KAPLI TABLET,28 ADET …
Matched Products: … TEVETEN 600 MG FILM KAPLI TABLET, 28 ADET …

Upadacitinib

Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. Rheumatoid arthritis is a chronic autoimmune inflammatory disease affecting the peripheral joints. It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage...
Approved
Investigational
Matched Products: … RİNVOQ 15 MG UZATILMIŞ SALIMLI TABLET, 28 ADET …

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Mixtures name: … STRODAY D3 2G/800 IU SAŞE , 28 SAŞE ... RICAVIS 6MG/1000MG/880IU EFERVASAN TABLET, 28 ADET ... OSTEOCAL 12MG/1000MG/880IU EFERVESAN TABLET, 28 ADET …
Matched Products: … YUMUŞAK KAPSÜL, 28 KAPSÜL ... YYUX Organic Liquid Vitamin D3 Drops For Baby 0-3 years 400 IU …

Thalidomide

A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of inflammatory disorders and cancers. Thalidomide displays immunosuppressive and anti-angiogenic activity through modulating the release of inflammatory mediators like tumor necrosis factor-alpha...
Approved
Investigational
Withdrawn
Matched Products: … THALIDOMIDE CELGENE 50 MG SERT KAPSUL, 28 ADET …

Manidipine

Manidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive. It is selective for vasculature and does not produce effects on the heart at clinically relevant dosages.
Approved
Investigational
Matched Products: … IPERTEN 20 MG TABLET, 28 ADET …

Methenamine

Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Approved
Vet approved
Matched Products: … HIPPURIN 1 GR FILM TABLET, 28 ADET …

Pregabalin

Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Products: … ALYSE 75 MG KAPSUL, 28 ADET ... ALYSE 150 MG KAPSUL, 28 ADET ... ALYSE 300 MG KAPSUL, 28 ADET …
Displaying drugs 26 - 50 of 1699 in total