Displaying drugs 26 - 50 of 54 in total
Minocycline
Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Tretinoin
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Beta vulgaris pollen
Beta vulgaris pollen is the pollen of the Beta vulgaris plant. Beta vulgaris pollen is mainly used in allergenic testing.
Approved
Matched Name: … Beta vulgaris pollen …
Matched Description: … Beta vulgaris pollen is the pollen of the Beta vulgaris plant. ... Beta vulgaris pollen is mainly used in allergenic testing. …
Matched Description: … Beta vulgaris pollen is the pollen of the Beta vulgaris plant. ... Beta vulgaris pollen is mainly used in allergenic testing. …
Northern bluefin tuna
Northern bluefin tuna allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Thunnus vulgaris flesh ... Thynnus vulgaris flesh …
Atlantic halibut
Atlantic halibut allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Hippoglossus vulgaris flesh …
Atlantic mackerel
Atlantic mackerel allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Scomber vulgaris flesh …
Azelaic acid
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is also produced by Malassezia furfur, also known as Pityrosporum ovale, which is a species of fungus that is normally found on human skin. Azelaic acid is effective against a number of skin conditions, such...
Approved
Clascoterone
Clascoterone (cortexolone 17α-propionate, CB-03-01) is a novel antagonist of androgen receptors. It binds to androgen receptors with high affinity. By competing with androgens for binding to androgen receptors, clascoterone works by blocking the androgen receptor signalling cascades that promote acne pathogenesis, such as sebaceous gland proliferation, excess sebum production, and...
Approved
Investigational
Matched Description: … A218846] In August 2020, FDA approved clascoterone for the first-in-class topical treatment of acne (acne vulgaris …
Benzoyl peroxide
Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Spironolactone
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … L44602] Off-label uses of spironolactone include hirsutism, female pattern hair loss, and adult acne vulgaris …
Carindacillin
Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. It is no longer marketed in the United States.
Approved
Investigational
Mezlocillin
Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Approved
Investigational
Netilmicin
Netilmicin is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity. Netilmicin inhibits protein synthesis in susceptible organisms by binding to the bacterial 30S ribosomal subunit and interfering with mRNA binding and the acceptor tRNA site. The bactericidal effect...
Approved
Investigational
Acetyl sulfisoxazole
Sulfisoxazole acetyl is an ester of sulfisoxazole, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, dihydropteroate synthase, preventing the incorporation of PABA into dihydrofolic acid, which is the precursor of folic acid. This process causes...
Approved
Vet approved
Cantharidin
Cantharidin is a naturally occurring odorless, colorless fatty substance of the terpenoid class that is produced as an oral fluid in the alimentary canal of the male blister beetle.[A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin to a female beetle as a copulatory...
Approved
Investigational
Rituximab
Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Bambusa vulgaris top
Bambusa vulgaris top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Bambusa Vulgaris Extract ... Bambusa Vulgaris Top Extract ... Bambusa Vulgaris (Bamboo) Extract …
Matched Name: … Bambusa vulgaris top …
Matched Description: … Bambusa vulgaris top is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Name: … Bambusa vulgaris top …
Matched Description: … Bambusa vulgaris top is a plant/plant extract used in some OTC (over-the-counter) products. …
Prunus armeniaca seed
Prunus armeniaca seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Armeniaca Vulgaris Seed …
Olumacostat glasaretil
Olumacostat glasaretil has been used in trials studying the treatment of Acne Vulgaris.
Investigational
Matched Description: … Olumacostat glasaretil has been used in trials studying the treatment of Acne Vulgaris. …
Ianalumab
Ianalumab is under investigation in clinical trial NCT01930175 (Study of Efficacy and Safety of VAY736 in Patients With Pemphigus Vulgaris).
Investigational
Matched Description: … investigation in clinical trial NCT01930175 (Study of Efficacy and Safety of VAY736 in Patients With Pemphigus Vulgaris …
Nadifloxacin
Nadifloxacin has been used in trials studying the treatment of Acne Vulgaris.
Investigational
Matched Description: … Nadifloxacin has been used in trials studying the treatment of Acne Vulgaris. …
PF-05175157
PF-05175157 has been used in trials studying the basic science and treatment of Acne Vulgaris, Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus Type 2, and Diabetes Mellitus, Type 2, among others.
Investigational
Matched Description: … PF-05175157 has been used in trials studying the basic science and treatment of Acne Vulgaris, Diabetes …
Gevokizumab
Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others. Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of...
Investigational
Matched Description: … Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's …
Displaying drugs 26 - 50 of 54 in total