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Displaying drugs 976 - 1000 of 1083 in total

Flavoxate

A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Approved
Matched Description: … A drug that has been used in various urinary syndromes and as an antispasmodic. ... Its therapeutic usefulness and its mechanism of action are not clear. ... It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity …
Matched Salts name: … Flavoxate hydrochloride …
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Genito Urinary System and Sex Hormones …
Matched Products: … Flavoxate Hydrochloride …

Nemvaleukin alfa

Investigational
Matched Synonyms: … 75-133-interleukin 2 (125-serine) (human) fusion protein with peptide linker (gg) fusion protein with ... 75-133-Interleukin 2 [125-serine] (human) fusion protein with peptide linker (GG) fusion protein with …

AQ-13 free base

Investigational
Matched Synonyms: … N'-(7-chloroquinolin-4-yl)-n,n-diethyl-propane-1,3-diamine …

(2R)-3-(phosphonooxy)propane-1,2-diyl diheptanoate

Experimental
Matched Name: … (2R)-3-(phosphonooxy)propane-1,2-diyl diheptanoate …

Gemcitabine

Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...
Approved
Matched Description: … Gemcitabine is a nucleoside analog and a chemotherapeutic agent. ... [L32950] It is also being investigated in other cancer and tumour types. ... work by replacing the building blocks of nucleic acids during DNA elongation, arresting tumour growth and …
Matched Salts name: … Gemcitabine hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Gemcitabine Hydrochloride ... Gemcitabine hydrochloride ... GEMCITABINE HYDROCHLORIDE …

N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan

Experimental
Matched Name: … N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan …

Moxifloxacin

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Description: … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …
Matched Salts name: … Moxifloxacin hydrochloride ... Moxifloxacin hydrochloride monohydrate …
Matched Products: … Moxifloxacin Hydrochloride ... MOXIFLOXACIN HYDROCHLORIDE ... Apo-moxifloxacin Hydrochloride …

Nortriptyline

Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Description: … and other conditions. ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts name: … Nortriptyline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Nortriptyline Hydrochloride …

Maprotiline

Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Description: … TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and ... be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and …
Matched Salts name: … Maprotiline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Maprotiline Hydrochloride …

Mitoxantrone

An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Salts name: … Mitoxantrone hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Mitoxantrone Hydrochloride …

Vardenafil

Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Description: … selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and ... [L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial ... cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the synthesis …
Matched Salts name: … Vardenafil hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Vardenafil hydrochloride ... Vardenafil Hydrochloride …

TP-252

TP-252 consists of magnesium L-lysinate bis-eicosapentaenoate, an ionizable salt of eicosapentaenoic acid (EPA), currently being investigated to treat familial adenomatous polyposis.
Investigational
Matched Synonyms: … Magnesium lysinate bis eicosapentaenoate …
Matched Description: … TP-252 consists of magnesium L-lysinate bis-eicosapentaenoate, an ionizable salt of eicosapentaenoic …

methyl 4-bromo-N-[8-(hydroxyamino)-8-oxooctanoyl]-L-phenylalaninate

Experimental
Matched Name: … methyl 4-bromo-N-[8-(hydroxyamino)-8-oxooctanoyl]-L-phenylalaninate …

Perenostobart

Perenostobart is an alpha-CD39 IgG4 monoclonal antibody.
Investigational
Matched Synonyms: … Immunoglobulin G4 [229-proline], anti-(human ectonucleoside triphosphate diphosphohydrolase 1) (human …

Anvatabart opadotin

Investigational
Matched Synonyms: … Immunoglobulin G1 [121-(4-acetylphenylalanine),de-450-lysine], anti-(human epidermal growth factor receptor ... Immunoglobulin G1-kappa, anti-[Homo sapiens ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Naphazoline

Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations …
Matched Mixtures name: … Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate …
Matched Salts name: … Naphazoline hydrochloride …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Naphazoline Hydrochloride …

N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE

Experimental
Matched Name: … N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE …

Desipramine

Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). ... as amitriptyline and clomipramine. …
Matched Salts name: … Desipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Desipramine Hydrochloride …

LM-030

Investigational
Matched Synonyms: … L-ISOLEUCINE, N2-(2-METHYL-1-OXOPROPYL)-L-GLUTAMINYL-L-THREONYL-L-LEUCYL-(.ALPHA.S,3S,6R)-3-AMINO-6-HYDROXY …

N-{(2S)-3-[(1R)-1-aminoethyl](hydroxy)phosphoryl-2-benzylpropanoyl}-L-phenylalanine

Experimental
Matched Name: … N-{(2S)-3-[(1R)-1-aminoethyl](hydroxy)phosphoryl-2-benzylpropanoyl}-L-phenylalanine …

2,2-bis(4-hydroxy-3-tert-butylphenyl)propane

TBD has been used in trials studying the treatment of Adenocarcinoma.
Investigational
Matched Name: … 2,2-bis(4-hydroxy-3-tert-butylphenyl)propane …

Midazolam

Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Description: … and endoscopic procedures as pre-anesthetic medication, and as an adjunct to local anesthesia. ... short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and ... This drug is unique from others in this class due to its rapid onset of effects and short duration of …
Matched Salts name: … Midazolam hydrochloride …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Matched Products: … Midazolam Hydrochloride ... Midazolam hydrochloride ... MIDAZOLAM HYDROCHLORIDE …

Methylprednisolone

Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …
Matched Products: … PROLON …

Pidolic acid

Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Matched Synonyms: … 5-oxo-L-proline …
Matched Description: … occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and ... Pidolic acid, in general, is found in large quantities in brain tissue and other tissues in bound form …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester

Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester …
Displaying drugs 976 - 1000 of 1083 in total