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Displaying drugs 101 - 125 of 8064 in total

Lutetium Lu 177 dotatate

A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of treatments called Peptide Receptor Radionuclide Therapy (PRRT), which involves targeting tumours with molecules carrying radioactive particles that bind to specific receptors expressed by the tumour. Lutetium Lu 177 dotatate may also be referred to as...
Approved
Investigational
Matched Description: … The presence of a radioligand allows monitoring of treatment response post therapy and prior to next ... fraction of the dose delivery which may be clinically beneficial in estimating the intensity of lesion ... A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of …
Matched Categories: … Diagnostic Uses of Chemicals …

Zinc ascorbate

Approved
Nutraceutical
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Hetacillin

Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Hetacillin has in vitro activity against gram-positive and gram-negative...
Approved
Vet approved
Withdrawn
Matched Description: … The name "penicillin" can either refer to several variants of penicillin available, or to the group of ... The bactericidal activity of Hetacillin results from the inhibition of cell wall synthesis and is mediated ... Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused …
Matched Categories: … combinations of penicillins …

Fluoxymesterone

An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Description: … , and in the treatment of breast neoplasms in women. ... An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Iopanoic acid

Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography.
Approved
Withdrawn
Matched Categories: … Diagnostic Uses of Chemicals …

Fludeoxyglucose (18F)

Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PET). It is administered by intravenous injection.
Approved
Investigational
Matched Categories: … Diagnostic Uses of Chemicals …

Romosozumab

Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant to other osteoperosis therapies . Romosozumab prevents bone resorption and induces the formation of bone though it is associated...
Approved
Investigational
Matched Description: … increased risk of cardiac death, heart attack, and stroke in one study[L5921,L5924]. ... women at high risk of fracture and patients who have failed in other treatments or are intolerant to ... Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Sultamicillin

Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Approved
Investigational
Matched Description: … Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated …
Matched Categories: … combinations of penicillins …

Urofollitropin

Urofollitropin is a urinary-derived follicle-stimulating hormone (FSH) that is extracted and purified from human urine samples. It consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51...
Approved
Vet approved
Matched Description: … It consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Metaxalone

Metaxalone is a moderate to strong muscle relaxant used in the symptomatic treatment of musculoskeletal pain caused by strains, sprains, and other musculoskeletal conditions. It is marketed by King Pharmaceuticals under the brand name Skelaxin®. Its main mechanism of action is thought to involve general central nervous system depression. Metaxalone...
Approved
Matched Description: … Metaxalone is a moderate to strong muscle relaxant used in the symptomatic treatment of musculoskeletal ... Its main mechanism of action is thought to involve general central nervous system depression. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Sulthiame

Approved
Matched Categories: … combinations of sulfonamides …

Bromotheophylline

Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. Bromotheophylline is categorized on the FDA as a drug substance with an inactive...
Approved
Matched Description: … Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline ... bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of …
Matched Categories: … combinations of xanthines …

Nirmatrelvir

Nirmatrelvir (PF-07321332) is an orally bioavailable 3C-like protease (3CLPRO) inhibitor that is the subject of clinical trial NCT04756531. 3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2. Without the activity of the SARS-CoV-2 3CLPRO, nonstructural proteins (including proteases) cannot be released to perform their functions, inhibiting viral replication.[A234224,A234229,A234234]...
Approved
Investigational
Matched Description: … Nirmatrelvir (PF-07321332) is an orally bioavailable 3C-like protease (3CLPRO) inhibitor that ... ,A234229,A234234] In 2020, Pfizer was investigating another potential treatment for SARS-CoV-2, [PF ... is advantageous in that it can be prescribed to patients before they require hospitalization, while [PF …

Nuvaxovid

SARS-CoV-2, the causative agent of COVID-19, relies on the interaction between its trimeric spike (S) glycoprotein and angiotensin-converting enzyme 2 (hACE2) expressed on host cells in order to establish a productive infection in humans. Antibodies directed against the S protein are capable of blocking S-hACE2 interactions and neutralizing viral particles...
Approved
Investigational
Matched Description: … SARS-CoV-2, the causative agent of COVID-19, relies on the interaction between its trimeric spike (S) ... COVID-19 in adults, which was expanded to include patients ≥12 years of age in August 2022. ... [A243789] Antibodies directed against the S protein are capable of blocking S-hACE2 interactions and …

Carindacillin

Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. It is no longer marketed in the United States.
Approved
Investigational
Matched Description: … Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of [carbenicillin] marketed by …
Matched Categories: … combinations of penicillins …

Flortaucipir F-18

Flortaucipir F-18, also known as 18F-T807 and 18F-AV-1451, is a small indole molecule synthesized with a radioactive fluorine isotope. It is used as a marker in positron emission tomography (PET) imaging of patients suspected of having Alzheimer's disease. After crossing the blood-brain barrier, flortaucipir F-18 binds to aggregated tau protein,...
Approved
Investigational
Matched Description: … of having Alzheimer's disease. ... [A203933] It is used as a marker in positron emission tomography (PET) imaging of patients suspected ... After crossing the blood-brain barrier, flortaucipir F-18 binds to aggregated tau protein, a hallmark of …
Matched Categories: … Diagnostic Uses of Chemicals …

Lactulose

Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE).[FDA Label,L6199,L6202] Despite being first synthesized in 1929 , investigations regarding its possible use as a laxative for...
Approved
Matched Description: … Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative ... synthesized in 1929[A178081], investigations regarding its possible use as a laxative for the treatment of ... Essential Medicines as one of the most effective and safe medicines employed in a health system[L6205 …
Matched Products: … LACTULOSE AIWA PF 10G/15ML …

Alendronic acid

Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Description: … Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of ... It functions by preventing resorption of bone[FDA Label][A959]. …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Mezlocillin

Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Approved
Investigational
Matched Categories: … combinations of penicillins …

Econazole

A broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally.
Approved
Matched Categories: … combinations of imidazole derivatives ... Metabolic Side Effects of Drugs and Substances …

Bumetanide

Bumetanide is a sulfamyl diuretic.
Approved
Matched Categories: … combinations of sulfonamides ... Increased Diuresis at Loop of Henle …

Gadoteridol

Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine, and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions with abnormal vascularity or those thought to disrupt the normal blood-brain barrier.[A263076,A263081,L49871] It was 1 of the 3 macrocyclic gadolinium-based contrast agents (GBCAs)...
Approved
Investigational
Matched Description: … Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine ... , and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions ... [A263076,A263081,L49871] It was 1 of the 3 macrocyclic gadolinium-based contrast agents (GBCAs) that …
Matched Categories: … Diagnostic Uses of Chemicals …

Dienestrol

Dienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of...
Approved
Investigational
Matched Description: … the vagina (atrophic vaginitis), and inflammation of the urethra (atrophic urethritis). ... an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of ... are treated with vaginal estrogens include a genital skin condition (vulvar atrophy), inflammation of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Pyrazinamide

A pyrazine that is used therapeutically as an antitubercular agent.
Approved
Investigational
Matched Categories: … Drugs for Treatment of Tuberculosis …

Cycloserine

Antibiotic substance produced by Streptomyces garyphalus.
Approved
Matched Categories: … Drugs for Treatment of Tuberculosis …
Displaying drugs 101 - 125 of 8064 in total