Benzopyrroles with the nitrogen at the number one carbon adjacent to the benzyl portion, in contrast to ISOINDOLES which have the nitrogen away from the six-membered ring.
DrugDrug NameDrug Indication
DB00206ReserpineFoe the treatment of hypertension
DB00216EletriptanFor the acute treatment of migraine with or without aura in adults.
DB00305MitomycinFor treatment of malignant neoplasm of lip, oral cavity, pharynx, digestive organs, peritoneum, female breast, and urinary bladder. Also used as an adjunct to ab externo glaucoma surgery.
DB00309VindesineFor the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia and acute panmyelosis
DB00315ZolmitriptanFor the acute treatment of adult migraine with or without auras.
DB00328IndometacinOral indometacin is indicated for symptomatic management of moderate to severe rheumatoid arthritis including acute flares of chronic disease, moderate to severe ankylosing spondylitis, moderate to severe osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.[A177871,L6778] Intravenous indometacin is indicated to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants weighing between 500 and 1750 g when after 48 hours usual medical management (e.g., fluid restriction, diuretics, digitalis, respiratory support, etc.) is ineffective.[F4600]
DB00361Vinorelbine Vinorelbine tartrate is indicated for adults in the treatment of advanced non-small cell lung cancer (NSCLC), as a single therapy or in combination with other chemotherapeutic drugs [L1998]. Used in relapsed or refractory Hodgkin lymphoma, in combination with other chemotherapy agents [L2011]. For the treatment of desmoid tumor or aggressive fibromatosis, in combination with methotrexate [L2011]. For the treatment of recurrent or metastatic squamous cell head and neck cancer [L2011]. For the treatment of recurrent ovarian cancer [L2011]. For the treatment of metastatic breast cancer, in patients previously treated with anthracyline and/or taxane therapy [L2011]. For the treatment of HER2-positive, trastuzumab-resistant, advanced breast cancer in patients previously treated with a taxane, in combination with trastuzumab and everolimus [L2011].
DB00541VincristineTreatment of acute lymphocytic leukemia (ALL), Hodgkin lymphoma, non-Hodgkin lymphomas, Wilms' tumor, neuroblastoma, rhabdomyosarcoma. Liposomal vincristine is indicated for the treatment of relapsed Philadelphia chromosome-negative (Ph-) acute lymphoblastic leukemia (ALL).
DB00570VinblastineFor treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
DB00669SumatriptanFor the treatment of migraine attacks with or without aura.
DB00705DelavirdineFor the treatment of HIV-1 infection in combination with appropriate antiretroviral agents when therapy is warranted
DB00749EtodolacFor acute and long-term management of signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as for the management of pain.
DB00790PerindoprilFor the treatment of mild to moderate essential hypertension, mild to moderate congestive heart failure, and to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and stable coronary disease.
DB00808IndapamideFor the treatment of hypertension, alone or in combination with other antihypertensive drugs, as well as for the treatment of salt and fluid retention associated with congestive heart failure or edema from pregnancy (appropriate only in the management of edema of pathologic origin during pregnancy when clearly needed). Also used for the management of edema as a result of various causes.
DB00820TadalafilUsed for the treatment of erectile dysfunction.
DB00821CarprofenFor use as a pain reliever in the treatment of joint pain and post-surgical pain.
DB00904OndansetronIn the adult patient population: i) orally administered ondansetron tablets and orally disintegrating tablets (ODT) are indicated for: - the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, including high dose (ie. greater than or equal to 50 mg/m2) cisplatin therapy, and radiotherapy, and - the prevention and treatment of postoperative nausea and vomiting ii) intravenously administered ondansetron injection formulations are indicated for: - the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, including high dose (ie. greater than or equal to 50 mg/m2) cisplatin therapy, and - the prevention and treatment of postoperative nausea and vomiting In the pediatric (4-18 years of age) patient population: i) ondansetron was effective and well tolerated when given to children 4-12 years of age for the treatment of post-chemotherapy induced nausea and vomiting, ii) ondansetron tablets, ondansetron ODT, ondansetron injection are not indicated for the treatment of children 3 years of age or younger, iii) ondansetron tablets, ondansetron ODT, ondansetron injection are not indicated for use in any age group of the pediatric population for the treatment of post-radiotherapy induced nausea and vomiting, and iV) ondansetron tablets, ondansetron ODT, ondansetron injection are not indicated for use in any age group of the pediatric population for the treatment of postoperative nausea and vomiting In the geriatric (>65 years of age) patient population: i) efficacy and tolerance of ondansetron were similar to that observed in younger adults for the treatment of post-chemotherapy and radiotherapy-induced nausea and vomiting, and ii) clinical experience in the use of ondansetron in the prevention and treatment of postoperative nausea and vomiting is limited and is not indicated for use in the geriatric patient population
DB00918AlmotriptanFor the treatment of acute migraine headache in adults
DB00952NaratriptanFor the acute treatment of migraine attacks with or without aura in adults.
DB00953RizatriptanFor treatment of acute migraine attacks with or without aura.
DB00969AlosetronOnly for the treatment of symptoms of severe diarrhea-predominant irritable bowel syndrome (IBS) in women with chronic symptoms (generally lasting greater than 6 months) who does not present with anatomic or biochemical GI abnormalities and have not responded to conventional therapy.
DB00981PhysostigmineFor the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.
DB00998FrovatriptanFor the acute treatment of migraine attacks with or without aura in adults.
DB01065MelatoninUsed orally for jet lag, insomnia, shift-work disorder, circadian rhythm disorders in the blind (evidence for efficacy), and benzodiazepine and nicotine withdrawal. Evidence indicates that melatonin is likely effective for treating circadian rhythm sleep disorders in blind children and adults. It has received FDA orphan drug status as an oral medication for this use. A number of studies have shown that melatonin may be effective for treating sleep-wake cycle disturbances in children and adolescents with mental retardation, autism, and other central nervous system disorders. It appears to decrease the time to fall asleep in children with developmental disabilities, such as cerebral palsy, autism, and mental retardation. It may also improve secondary insomnia associated with various sleep-wake cycle disturbances. Other possible uses for which there is some evidence for include: benzodiazepine withdrawal, cluster headache, delayed sleep phase syndrome (DSPS), primary insomnia, jet lag, nicotine withdrawal, preoperative anxiety and sedation, prostate cancer, solid tumors (when combined with IL-2 therapy in certain cancers), sunburn prevention (topical use), tardive dyskinesia, thrombocytopenia associated with cancer, chemotherapy and other disorders.
DB01089DeserpidineFor the treatment of hypertension.
DB01136CarvedilolFor the treatment of mild or moderate (NYHA class II or III) heart failure of ischemic or cardiomyopathic origin.
DB01180RescinnamineFor the treatment of hypertension.
DB01392YohimbineIndicated as a sympatholytic and mydriatic. Impotence has been successfully treated with yohimbine in male patients with vascular or diabetic origins and psychogenic origins.
DB01426AjmalineFor use as an antiarrhythmic agent.
DB014415-Methoxy-N,N-diisopropyltryptamineNot Available
DB01445BufotenineNot Available
DB01446IndopanNot Available
DB01488DimethyltryptamineSome people use this compound as a psychedelic inducing agent.
DB01546EtryptamineDeveloped in the 1960's for use as an antidepressant before market withdrawal in 1962.
DB01618MolindoneMolindone is used for the management of the manifestations of psychotic disorders.
DB019337-HydroxystaurosporineNot Available
DB02010StaurosporineNot Available
DB02095IsatinNot Available
DB02152K-252aNot Available
DB04823OxyphenisatinNot Available
DB04867LintitriptFor the treatment of pancreatic cancer and appetite disorders.
DB04877VoacamineFor the treatment of malaria. Also under investigation for the modulation of multidrug resistance in cancer cells.
DB04882EdotecarinClinical studies with edotecarin have shown activity in subjects with colorectal cancer, esophageal cancer and other solid tumors.
DB04885CilansetronFor the treatment of symptoms associated with irritable bowel syndrome.
DB04892PhenserineFor the treatment of Alzheimer's disease (AD).
DB05168VintafolideInvestigated for use/treatment in solid tumors.
DB05403CEP-1347Investigated for use/treatment in asthma and parkinson's disease.
DB06362BecatecarinInvestigated for use/treatment in cancer/tumors (unspecified), liver cancer, gastric cancer, and leukemia (unspecified).
DB06469LestaurtinibInvestigated for use/treatment in pancreatic cancer, prostate cancer, and leukemia (myeloid).
DB06478PorfiromycinInvestigated for use/treatment in head and neck cancer.
DB06595MidostaurinInvestigated for use/treatment in adult patients with high-risk acute myeloid leukemia (AML) who are FLT3 mutation-positive, agressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN), or mast cell leukemia (MCL).
DB06684VilazodoneVilazodone is approved for treatment of major depressive disorder[Label,A38477,A177622].
DB073019H-CARBAZOLENot Available
DB08839SerotoninNot Available
DB08950IndoraminNot Available
DB09012CarbazochromeIndicated for capillary and parenchymal hemorrhage (trauma, tonsillectomy, during surgery), intestinal bleeding, and thrombocytopenic purpura.
DB09244PirlindoleFor the treatment of major depression. It is being studied in the treatment of fibromyalgia pain syndrome. One study determined that the effect of pirlindole on sensorimotor performance while driving a motor vehicle shows many similarities to that of placebo. The drug appears to stimulate the central nervous system, rather than exhibit a sedative effect, like many antidepressants. Because of its selective, reversible inhibition of monoamine oxidase (MAO-A) and short half-life, unpleasant "cheese effects" are avoided. This refers to the effects of consuming tyramine-rich foods, such as cheese while medicated with monoamine oxidase inhibitors, leading to severe headaches and hypertension [L1395]. of The available evidence supports pirlindole as a safe and effective treatment option for the management of depression and fibromyalgia syndrome [L1394].
DB09306MetralindoleInvestigated for the treatment of depression.
DB09374Indocyanine green acid formFor Determining Cardiac Output, Hepatic Function and Liver Blood Flow For ophthalmic angiography
DB11363AlectinibAlectinib is a kinase inhibitor indicated for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive, metastatic non-small cell lung cancer (NSCLC) who have progressed on or are intolerant to crizotinib. This indication is approved under accelerated approval based on tumor response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials.
DB11577Indigotindisulfonic AcidThis drug was initially used as a kidney function test. The main application of indigo carmine at this time is localizing and visualizing ureteral orifices during cystoscopy and ureteral catheterization procedures [L2215].
DB11641VinflunineFor use as a monotherapy in adults with advanced or transitional cell carcinoma of the urothelial tract after failure of a prior platinum-containing therapy [L2381].
DB11664PsilocybineNot Available
DB11900OC-459Not Available
DB12011FevipiprantNot Available
DB12027SerdemetanNot Available
DB12131VinpocetineNot Available
DB12593ApaziquoneNot Available
DB12674LurbinectedinNot Available
DB12756TAK-901Not Available
DB12971PactimibeNot Available
DB13036RamatrobanNot Available
DB13374VincamineNot Available
DB13496IprindoleNot Available
DB13527ProglumetacinNot Available
DB13541IprazochromeNot Available
DB13555PrajmalineNot Available
DB13575BietaserpineNot Available
DB13641MetisazoneNot Available
DB13651LorajmineNot Available
DB13783AcemetacinAcemetacin is not FDA, Canada or EMA approved, but in the countries where it is marketed it is indicated for the symptomatic treatment of pain and swelling in acute inflammation of the joints in rheumathoid arthritis, osteoarthritis, low back pain and post-surgical pain.[L1045] It is also indicated for the treatment of chronic inflammation of the joints in presence of rheumatoid arthritis, treatment of ankylosing spondylitis, treatment of irritation in the joints and spinal column caused by degenerative disorders, treatment of inflammatory soft-tissue rheumatism syndrome and painful swelling and inflammation caused by injury.[L1044, L1046]
DB13793VinburnineNot Available
DB13808MebhydrolinNot Available
DB13875HarmalineNot Available
DB13978SelisistatNot Available
DB140105-methoxy-N,N-dimethyltryptamineNot Available
DB14627Oxyphenisatin acetateNot Available
DB07950Indoleacetic acidNot Available
DB04275N-acetylserotoninNot Available
DB09363Rauwolfia serpentina rootRauwolfia alkaloids are indicated in the treatment of hypertension [L1614]. Rauwolfia alkaloids have been used for relief of symptoms in agitated psychotic states such as schizophrenia; however, use as antipsychotics and sedatives have been replaced with the use of more effective, safer agents [L1614].
DB14729RebeccamycinNot Available
DB01430AlmitrineFor the treatment of chronic obstructive pulmonary disease.
DB01460DiethyltryptamineNot Available
DB14882CEP-9722Not Available
DB1509618-methoxycoronaridineNot Available
DB15317PosiphenNot Available
DB15375TozuleristideNot Available
DrugDrug NameTargetType
DB00206ReserpineSynaptic vesicular amine transportertarget
DB00206ReserpineMultidrug resistance protein 1transporter
DB00206ReserpineSolute carrier family 22 member 1transporter
DB00206ReserpineBile salt export pumptransporter
DB00206ReserpineCanalicular multispecific organic anion transporter 1transporter
DB00206ReserpineSolute carrier family 22 member 2transporter
DB00206ReserpineCytochrome P450 3A5enzyme
DB00206ReserpineChromaffin granule amine transportertarget
DB00206ReserpineBaculoviral IAP repeat-containing protein 5target
DB00206ReserpineSolute carrier organic anion transporter family member 1B1transporter
DB00206ReserpineSolute carrier organic anion transporter family member 2B1transporter
DB00216Eletriptan5-hydroxytryptamine receptor 1Dtarget
DB00216Eletriptan5-hydroxytryptamine receptor 7target
DB00216Eletriptan5-hydroxytryptamine receptor 1Atarget
DB00216Eletriptan5-hydroxytryptamine receptor 1Etarget
DB00216Eletriptan5-hydroxytryptamine receptor 2Btarget
DB00216Eletriptan5-hydroxytryptamine receptor 1Ftarget
DB00216Eletriptan5-hydroxytryptamine receptor 1Btarget
DB00216EletriptanCytochrome P450 3A4enzyme
DB00216EletriptanCytochrome P450 2D6enzyme
DB00216EletriptanCytochrome P450 2C9enzyme
DB00216EletriptanCytochrome P450 2C19enzyme
DB00216EletriptanProstaglandin G/H synthase 1enzyme
DB00216EletriptanCytochrome P450 2A6enzyme
DB00216EletriptanMultidrug resistance protein 1transporter
DB00305MitomycinDNAtarget
DB00305MitomycinNADPH--cytochrome P450 reductaseenzyme
DB00309VindesineTubulin beta-1 chaintarget
DB00309VindesineCytochrome P450 3A4enzyme
DB00315Zolmitriptan5-hydroxytryptamine receptor 1Dtarget
DB00315Zolmitriptan5-hydroxytryptamine receptor 1Btarget
DB00315Zolmitriptan5-hydroxytryptamine receptor 1Ftarget
DB00315ZolmitriptanCytochrome P450 1A2enzyme
DB00315ZolmitriptanAmine oxidase [flavin-containing] Aenzyme
DB00315Zolmitriptan5-hydroxytryptamine receptor 1Atarget
DB00328IndometacinProstaglandin G/H synthase 1target
DB00328IndometacinProstaglandin G/H synthase 2target
DB00328IndometacinCytochrome P450 2C19enzyme
DB00328IndometacinUDP-glucuronosyltransferase 1-9enzyme
DB00328IndometacinPhospholipase A2, membrane associatedtarget
DB00328IndometacinProstaglandin reductase 2target
DB00328IndometacinLactoylglutathione lyasetarget
DB00328IndometacinProstaglandin D2 receptor 2target
DB00328IndometacinPeroxisome proliferator-activated receptor gammatarget
DB00328IndometacinSerum albumincarrier
DB00328IndometacinCanalicular multispecific organic anion transporter 2transporter
DB00328IndometacinMultidrug resistance-associated protein 4transporter
DB00328IndometacinMultidrug resistance-associated protein 6transporter
DB00328IndometacinMultidrug resistance protein 1transporter
DB00328IndometacinMultidrug resistance-associated protein 1transporter
DB00328IndometacinSolute carrier organic anion transporter family member 1A2transporter
DB00328IndometacinSolute carrier family 22 member 6transporter
DB00328IndometacinSolute carrier family 22 member 8transporter
DB00328IndometacinCanalicular multispecific organic anion transporter 1transporter
DB00328IndometacinATP-binding cassette sub-family C member 11transporter
DB00328IndometacinSolute carrier family 22 member 11transporter
DB00328IndometacinSodium/bile acid cotransportertransporter
DB00328IndometacinSolute carrier family 22 member 7transporter
DB00328IndometacinCytochrome P450 2C9enzyme
DB00328IndometacinUDP-glucuronosyltransferase 1-1enzyme
DB00328IndometacinLiver carboxylesterase 1enzyme
DB00328IndometacinUDP-glucuronosyltransferase 2B7enzyme
DB00328IndometacinPeroxisome proliferator-activated receptor alphatarget
DB00328IndometacinAldo-keto reductase family 1 member C3target
DB00328IndometacinSolute carrier organic anion transporter family member 1B1transporter
DB00328IndometacinBile salt export pumptransporter
DB00361VinorelbineTubulin beta chaintarget
DB00361VinorelbineCytochrome P450 3A4enzyme
DB00361VinorelbineMultidrug resistance protein 1transporter
DB00361VinorelbineCytochrome P450 2D6enzyme
DB00541VincristineTubulin beta chaintarget
DB00541VincristineCytochrome P450 3A4enzyme
DB00541VincristineCytochrome P450 3A5enzyme
DB00541VincristineCytochrome P450 3A7enzyme
DB00541VincristineMultidrug resistance protein 1transporter
DB00541VincristineCanalicular multispecific organic anion transporter 2transporter
DB00541VincristineSolute carrier family 22 member 3transporter
DB00541VincristineMultidrug resistance-associated protein 1transporter
DB00541VincristineMultidrug resistance-associated protein 7transporter
DB00541VincristineCanalicular multispecific organic anion transporter 1transporter
DB00541VincristineBile salt export pumptransporter
DB00541VincristineATP-binding cassette sub-family G member 2transporter
DB00541VincristineTubulin alpha-4A chaintarget
DB00541VincristineRalA-binding protein 1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B3transporter
DB00570VinblastineTubulin beta chaintarget
DB00570VinblastineTranscription factor AP-1target
DB00570VinblastineCytochrome P450 3A4enzyme
DB00570VinblastineMultidrug resistance protein 1transporter
DB00570VinblastineMultidrug resistance-associated protein 1transporter
DB00570VinblastineCanalicular multispecific organic anion transporter 1transporter
DB00570VinblastineMultidrug resistance-associated protein 6transporter
DB00570VinblastineBile salt export pumptransporter
DB00570VinblastineTubulin alpha-1A chaintarget
DB00570VinblastineTubulin delta chaintarget
DB00570VinblastineTubulin epsilon chaintarget
DB00570VinblastineTubulin gamma-1 chaintarget
DB00570VinblastineCytochrome P450 2D6enzyme
DB00570VinblastineSolute carrier organic anion transporter family member 1B1transporter
DB00669Sumatriptan5-hydroxytryptamine receptor 1Dtarget
DB00669Sumatriptan5-hydroxytryptamine receptor 1Btarget
DB00669Sumatriptan5-hydroxytryptamine receptor 1Ftarget
DB00669SumatriptanAmine oxidase [flavin-containing] Aenzyme
DB00669Sumatriptan5-hydroxytryptamine receptor 1Atarget
DB00669SumatriptanSolute carrier organic anion transporter family member 1A2transporter
DB00669SumatriptanMultidrug resistance protein 1transporter
DB00669SumatriptanATP-binding cassette sub-family G member 2transporter
DB00669SumatriptanSolute carrier organic anion transporter family member 1B1transporter
DB00705DelavirdineCytochrome P450 3A4enzyme
DB00705DelavirdineCytochrome P450 2C9enzyme
DB00705DelavirdineCytochrome P450 2D6enzyme
DB00705DelavirdineCytochrome P450 3A5enzyme
DB00705DelavirdineCytochrome P450 3A7enzyme
DB00705DelavirdineCytochrome P450 2C19enzyme
DB00705DelavirdineCytochrome P450 2C8enzyme
DB00705DelavirdineReverse transcriptase/RNaseHtarget
DB00749EtodolacProstaglandin G/H synthase 1target
DB00749EtodolacProstaglandin G/H synthase 2target
DB00749EtodolacCytochrome P450 2C9enzyme
DB00749EtodolacUDP-glucuronosyltransferase 1-9enzyme
DB00749EtodolacRetinoic acid receptor RXR-alphatarget
DB00749EtodolacSerum albumincarrier
DB00749EtodolacSolute carrier family 22 member 6transporter
DB00749EtodolacUDP-glucuronosyltransferase 1-3enzyme
DB00749EtodolacUDP-glucuronosyltransferase 1-10enzyme
DB00749EtodolacUDP-glucuronosyltransferase 2B7enzyme
DB00790PerindoprilAngiotensin-converting enzymetarget
DB00790PerindoprilSolute carrier family 15 member 1transporter
DB00790PerindoprilSolute carrier family 15 member 2transporter
DB00790PerindoprilCholinesteraseenzyme
DB00790PerindoprilSecreted frizzled-related protein 4target
DB00808IndapamideCytochrome P450 3A4enzyme
DB00808IndapamideSolute carrier family 12 member 3target
DB00820TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00820TadalafilCytochrome P450 3A4enzyme
DB00820TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
DB00820TadalafilCytochrome P450 3A5enzyme
DB00821CarprofenProstaglandin G/H synthase 2target
DB00821CarprofenProstaglandin G/H synthase 1target
DB00821CarprofenSolute carrier family 22 member 6transporter
DB00904Ondansetron5-hydroxytryptamine receptor 3Atarget
DB00904OndansetronCytochrome P450 3A4enzyme
DB00904OndansetronCytochrome P450 1A2enzyme
DB00904OndansetronCytochrome P450 2D6enzyme
DB00904OndansetronCytochrome P450 3A5enzyme
DB00904OndansetronCytochrome P450 3A7enzyme
DB00904Ondansetron5-hydroxytryptamine receptor 4target
DB00904Ondansetron5-hydroxytryptamine receptor 1Atarget
DB00904Ondansetron5-hydroxytryptamine receptor 1Btarget
DB00904OndansetronMu-type opioid receptortarget
DB00904OndansetronCytochrome P450 2C9enzyme
DB00904OndansetronCytochrome P450 2E1enzyme
DB00918Almotriptan5-hydroxytryptamine receptor 1Dtarget
DB00918Almotriptan5-hydroxytryptamine receptor 1Btarget
DB00918AlmotriptanCytochrome P450 3A4enzyme
DB00918AlmotriptanCytochrome P450 2D6enzyme
DB00918AlmotriptanAmine oxidase [flavin-containing] Aenzyme
DB00918AlmotriptanDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00918AlmotriptanCytochrome P450 2C19enzyme
DB00918AlmotriptanCytochrome P450 2E1enzyme
DB00918AlmotriptanCytochrome P450 2C8enzyme
DB00952Naratriptan5-hydroxytryptamine receptor 1Dtarget
DB00952Naratriptan5-hydroxytryptamine receptor 1Btarget
DB00952Naratriptan5-hydroxytryptamine receptor 1Ftarget
DB00952Naratriptan5-hydroxytryptamine receptor 1Atarget
DB00952NaratriptanAmine oxidase [flavin-containing] Aenzyme
DB00953Rizatriptan5-hydroxytryptamine receptor 1Dtarget
DB00953Rizatriptan5-hydroxytryptamine receptor 1Btarget
DB00953Rizatriptan5-hydroxytryptamine receptor 1Ftarget
DB00953RizatriptanAmine oxidase [flavin-containing] Aenzyme
DB00969Alosetron5-hydroxytryptamine receptor 3Atarget
DB00969AlosetronCytochrome P450 1A2enzyme
DB00969AlosetronCytochrome P450 2C9enzyme
DB00969AlosetronCytochrome P450 3A4enzyme
DB00969AlosetronCytochrome P450 2E1enzyme
DB00981PhysostigmineAcetylcholinesterasetarget
DB00981PhysostigmineNeuronal acetylcholine receptor subunit alpha-4target
DB00981PhysostigmineNeuronal acetylcholine receptor subunit beta-2target
DB00998Frovatriptan5-hydroxytryptamine receptor 1Dtarget
DB00998Frovatriptan5-hydroxytryptamine receptor 1Btarget
DB00998FrovatriptanCytochrome P450 1A2enzyme
DB01065MelatoninAcetylserotonin O-methyltransferasetarget
DB01065MelatoninMelatonin receptor type 1Atarget
DB01065MelatoninMelatonin receptor type 1Btarget
DB01065MelatoninNuclear receptor ROR-betatarget
DB01065MelatoninCalmodulintarget
DB01065MelatoninCalreticulintarget
DB01065MelatoninRibosyldihydronicotinamide dehydrogenase [quinone]target
DB01065MelatoninMyeloperoxidasetarget
DB01065MelatoninEstrogen receptor alphatarget
DB01065MelatoninEosinophil peroxidasetarget
DB01065MelatoninCytochrome P450 1A1enzyme
DB01065MelatoninCytochrome P450 1A2enzyme
DB01065MelatoninCytochrome P450 2C19enzyme
DB01065MelatoninCytochrome P450 2C9enzyme
DB01065MelatoninAcetylserotonin O-methyltransferaseenzyme
DB01065MelatoninIndoleamine 2,3-dioxygenase 1enzyme
DB01065MelatoninMyeloperoxidaseenzyme
DB01065MelatoninCytochrome P450 1B1enzyme
DB01065MelatoninSolute carrier family 22 member 8transporter
DB01065MelatoninCytochrome P450 19A1enzyme
DB01089DeserpidineSynaptic vesicular amine transportertarget
DB01136CarvedilolAlpha-1A adrenergic receptortarget
DB01136CarvedilolBeta-1 adrenergic receptortarget
DB01136CarvedilolNADH dehydrogenase [ubiquinone] 1 subunit C2target
DB01136CarvedilolBeta-2 adrenergic receptortarget
DB01136CarvedilolVascular endothelial growth factor Atarget
DB01136CarvedilolNatriuretic peptides Btarget
DB01136CarvedilolGap junction alpha-1 proteintarget
DB01136CarvedilolPotassium voltage-gated channel subfamily H member 2target
DB01136CarvedilolVascular cell adhesion protein 1target
DB01136CarvedilolCytochrome P450 2C9enzyme
DB01136CarvedilolCytochrome P450 2D6enzyme
DB01136CarvedilolXanthine dehydrogenase/oxidaseenzyme
DB01136CarvedilolMultidrug resistance protein 1transporter
DB01136CarvedilolCytochrome P450 1A2enzyme
DB01136CarvedilolCytochrome P450 3A4enzyme
DB01136CarvedilolCytochrome P450 1A1enzyme
DB01136CarvedilolCytochrome P450 2E1enzyme
DB01136CarvedilolProstaglandin G/H synthase 1enzyme
DB01136CarvedilolAlpha-1D adrenergic receptortarget
DB01136CarvedilolAlpha-1B adrenergic receptortarget
DB01136CarvedilolAlpha-2C adrenergic receptortarget
DB01136CarvedilolAlpha-2B adrenergic receptortarget
DB01136CarvedilolAlpha-2A adrenergic receptortarget
DB01136CarvedilolE-selectintarget
DB01136CarvedilolHypoxia-inducible factor 1-alphatarget
DB01136CarvedilolInward rectifier potassium channel 4target
DB01136CarvedilolUDP-glucuronosyltransferase 1-1enzyme
DB01180RescinnamineAngiotensin-converting enzymetarget
DB01392YohimbineAlpha-2A adrenergic receptortarget
DB01392YohimbineAlpha-2B adrenergic receptortarget
DB01392YohimbineAlpha-2C adrenergic receptortarget
DB01392Yohimbine5-hydroxytryptamine receptor 1Atarget
DB01392Yohimbine5-hydroxytryptamine receptor 1Btarget
DB01392Yohimbine5-hydroxytryptamine receptor 1Dtarget
DB01392YohimbineD(2) dopamine receptortarget
DB01392YohimbineD(3) dopamine receptortarget
DB01392Yohimbine5-hydroxytryptamine receptor 2Atarget
DB01392Yohimbine5-hydroxytryptamine receptor 2Ctarget
DB01392YohimbineCytochrome P450 2D6enzyme
DB01392YohimbineCytochrome P450 3A4enzyme
DB01392YohimbineATP-sensitive potassium channeltarget
DB01392Yohimbine5-hydroxytryptamine receptor 2Btarget
DB01426AjmalineAlpha-1-acid glycoprotein 1carrier
DB01426AjmalineSodium channel protein type 5 subunit alphatarget
DB01445BufotenineAmine oxidase [flavin-containing] Aenzyme
DB01445BufotenineAmine oxidase [flavin-containing] Benzyme
DB01488Dimethyltryptamine5-hydroxytryptamine receptor 6target
DB01488Dimethyltryptamine5-hydroxytryptamine receptor 2Atarget
DB01488DimethyltryptamineSigma non-opioid intracellular receptor 1target
DB01618MolindoneD(2) dopamine receptortarget
DB01618Molindone5-hydroxytryptamine receptor 1Atarget
DB01618Molindone5-hydroxytryptamine receptor 2Atarget
DB01618MolindoneMuscarinic acetylcholine receptor M1target
DB019337-Hydroxystaurosporine3-phosphoinositide-dependent protein kinase 1target
DB02010StaurosporineTyrosine-protein kinase Lcktarget
DB02010StaurosporineSerine/threonine-protein kinase pim-1target
DB02010StaurosporineTyrosine-protein kinase ITK/TSKtarget
DB02010StaurosporineTyrosine-protein kinase SYKtarget
DB02010StaurosporineMAP kinase-activated protein kinase 2target
DB02010StaurosporineGlycogen synthase kinase-3 betatarget
DB02010StaurosporineTyrosine-protein kinase CSKtarget
DB02010StaurosporineCyclin-dependent kinase 2target
DB02010StaurosporinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
DB02010Staurosporine3-phosphoinositide-dependent protein kinase 1target
DB02010StaurosporineProtein kinase C theta typetarget
DB02010StaurosporineTyrosine-protein kinase ZAP-70target
DB02010StaurosporineMultidrug resistance protein 1transporter
DB02010StaurosporineMuscarinic acetylcholine receptor M1target
DB02095IsatinAmine oxidase [flavin-containing] Btarget
DB02095IsatinAmine oxidase [flavin-containing] Benzyme
DB02152K-252aHepatocyte growth factor receptortarget
DB02152K-252aDual specificity mitogen-activated protein kinase kinase 1target
DB04867LintitriptCholecystokinin receptor type Atarget
DB04877VoacamineMultidrug resistance protein 1target
DB04882EdotecarinDNA topoisomerase 1target
DB04885Cilansetron5-hydroxytryptamine receptor 3Atarget
DB04892PhenserineAcetylcholinesterasetarget
DB04892PhenserineCholinesterasetarget
DB04892PhenserineAmyloid beta A4 proteintarget
DB05168VintafolideFolate receptor betatarget
DB05168VintafolideFolate receptor gammatarget
DB05168VintafolideFolate receptor alphatarget
DB05403CEP-1347Mitogen-activated protein kinase 12target
DB06362BecatecarinDNA topoisomerase 2-alphatarget
DB06362BecatecarinDNA topoisomerase 2-betatarget
DB06469LestaurtinibReceptor-type tyrosine-protein kinase FLT3target
DB06469LestaurtinibCytochrome P450 3A4enzyme
DB06478PorfiromycinXanthine dehydrogenase/oxidaseenzyme
DB06595MidostaurinProtein kinase C alpha typetarget
DB06595MidostaurinVascular endothelial growth factor receptor 2target
DB06595MidostaurinMast/stem cell growth factor receptor Kittarget
DB06595MidostaurinPlatelet-derived growth factor receptor alphatarget
DB06595MidostaurinPlatelet-derived growth factor receptor betatarget
DB06595MidostaurinReceptor-type tyrosine-protein kinase FLT3target
DB06595MidostaurinCYP3Aenzyme
DB06595MidostaurinCytochrome P450 1A2enzyme
DB06595MidostaurinCytochrome P450 2B6enzyme
DB06595MidostaurinCytochrome P450 2C8enzyme
DB06595MidostaurinCytochrome P450 2C9enzyme
DB06595MidostaurinCytochrome P450 2C19enzyme
DB06595MidostaurinCytochrome P450 2D6enzyme
DB06595MidostaurinCytochrome P450 2E1enzyme
DB06595MidostaurinCytochrome P450 3A4enzyme
DB06595MidostaurinCytochrome P450 3A5enzyme
DB06595MidostaurinCytochrome P450 3A7enzyme
DB06595MidostaurinCytochrome P450 3A43enzyme
DB06684Vilazodone5-hydroxytryptamine receptor 1Atarget
DB06684VilazodoneCytochrome P450 3A4enzyme
DB06684VilazodoneCytochrome P450 2D6enzyme
DB06684VilazodoneSodium-dependent serotonin transportertarget
DB06684VilazodoneCytochrome P450 2C19enzyme
DB073019H-CARBAZOLEFerredoxin CarActarget
DB073019H-CARBAZOLETerminal oxygenase component of carbazoletarget
DB08839SerotoninSolute carrier family 22 member 2transporter
DB08839SerotoninSodium-dependent serotonin transportertarget
DB08839Serotonin5-hydroxytryptamine receptor 2Atarget
DB08839Serotonin5-hydroxytryptamine receptor 3Atarget
DB08839Serotonin5-hydroxytryptamine receptor 3Btarget
DB08839SerotoninSynaptic vesicular amine transportertarget
DB08950IndoraminAlpha-1A adrenergic receptortarget
DB09244PirlindoleAmine oxidase [flavin-containing] Atarget
DB09244Pirlindole5-hydroxytryptamine receptor 1Atarget
DB09244PirlindoleAlpha-2A adrenergic receptortarget
DB09244PirlindoleAmine oxidase [flavin-containing] Aenzyme
DB09374Indocyanine green acid formCanalicular multispecific organic anion transporter 1transporter
DB09374Indocyanine green acid formIsocitrate dehydrogenase [NADP] cytoplasmicenzyme
DB09374Indocyanine green acid formGlutaminase kidney isoform, mitochondrialenzyme
DB09374Indocyanine green acid formBile salt export pumptransporter
DB11363AlectinibALK tyrosine kinase receptortarget
DB11363AlectinibATP-binding cassette sub-family G member 2transporter
DB11363AlectinibMultidrug resistance protein 1carrier
DB11577Indigotindisulfonic AcidAryl hydrocarbon receptortarget
DB11577Indigotindisulfonic AcidAlpha adrenergic receptortarget
DB11641VinflunineATP-binding cassette sub-family B member 5transporter
DB11641VinflunineMultidrug resistance protein 1transporter
DB11641VinflunineSerum albumincarrier
DB11641VinflunineHigh density lipoproteincarrier
DB11641Vinfluninealpha1-acid glycoproteincarrier
DB11641VinflunineCytochrome P450 3A4enzyme
DB11641VinflunineTubulin beta chaintarget
DB12131VinpocetineCytochrome P450 3A4enzyme
DB13036RamatrobanProstaglandin D2 receptor 2target
DB13783AcemetacinProstaglandin G/H synthase 1target
DB13783AcemetacinProstaglandin G/H synthase 2target
DB13783AcemetacinUDP-glucuronosyltransferase 2B7enzyme
DB13783AcemetacinMultidrug resistance-associated protein 1transporter
DB13875HarmalineHistamine N-methyltransferasetarget
DB13978SelisistatNAD-dependent protein deacetylase sirtuin-1target
DB140105-methoxy-N,N-dimethyltryptamine5-hydroxytryptamine receptor 1Atarget
DB140105-methoxy-N,N-dimethyltryptamine5-hydroxytryptamine receptor 2Atarget
DB140105-methoxy-N,N-dimethyltryptamineCytochrome P450 2D6enzyme
DB07950Indoleacetic acidGroup IIE secretory phospholipase A2target
DB07950Indoleacetic acidS-phase kinase-associated protein 1target
DB07950Indoleacetic acidKynurenine--oxoglutarate transaminase 1target
DB04275N-acetylserotoninSepiapterin reductasetarget
DB09363Rauwolfia serpentina rootSynaptic vesicular amine transportertarget
DB09363Rauwolfia serpentina rootMonoamine oxidaseenzyme
DB09363Rauwolfia serpentina rootSodium-dependent noradrenaline transportertransporter
DB09363Rauwolfia serpentina rootvesicular monoamine transporter 2 (VMAT2)transporter
DB01430AlmitrineSodium/potassium-transporting ATPase subunit alpha-1target