Pharmaceutic Aids

Substances which are of little or no therapeutic value, but are necessary in the manufacture, compounding, storage, etc., of pharmaceutical preparations or drug dosage forms. They include SOLVENTS, diluting agents, and suspending agents, and emulsifying agents. Also, ANTIOXIDANTS; PRESERVATIVES, PHARMACEUTICAL; COLORING AGENTS; FLAVORING AGENTS; VEHICLES; EXCIPIENTS; OINTMENT BASES.
DrugDrug NameDrug Indication
DB01032ProbenecidFor the reduction of serum uric acid concentrations in chronic gouty arthritis and tophaceous gout in patients with frequent disabling gout attacks. Has also been effectively used to promote uric acid excretion in hyperuricemia secondary to the administration of thiazide and related diuretics.
DB01839Propylene glycolNot Available
DB03754TromethamineFor the prevention and correction of metabolic acidosis.
DB10667TragacanthNot Available
DB11058PetrolatumFor use as an over the counter skin protectant [FDA Label]. Commonly used to treat diaper rash and chapped lips [FDA Label] [L858].
DB11061PovidoneWhen in complex with iodine, indicated for inducing antisepsis for prevention of infection in minor cuts, scrapes, and burns.
DB11063Polysorbate 80It is used as a solubilizer, antimicrobial preservative and disinfectant [L1853].
DB11105BenzalkoniumWhen used as an active ingredient in products like antibacterial, antiseptic, or disinfectant soaps, topical sanitizers, or cleaning agents, benzalkonium is primarily implemented in its salt form, benzalkonium chloride, where it may often be the only active ingredient present and indicated for the primary purpose of topical washing to decrease bacteria on skin [L1806]. Conversely, when implemented as an excipient ingredient in a variety of multidose aqueous nose, eye, or ear products, benzalkonium chloride is being used as the antimicrobial preservative of choice to facilitate effective bactericidal and fungicidal actions to help minimize the growth of unwanted organisms in the multidose containers [FDA Label].
DB11178Polysorbate 20Not Available
DB11230Magnesium Aluminum SilicateMagnesium aluminum silicate is used as an over the counter antacid for the self-treatment of heartburn, sour stomach, or acid indigestion [FDA Label].
DB11252Poloxamer 407Not Available
DB11333Poloxamer 188Indicated to reduce viscosity in the blood before transfusions.
DB11386ChlorobutanolNo approved therapeutic indications on its own.
DB11590ThimerosalUsed as preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes vaccines [L1671, L1672, L1673].
DB12176TricaprylinNot Available
DB13595AlmasilateAlmasilate is indicated for use as an antacid for the neutralization of excess stomach acid [F25]. It is subsequently also used for the symptomatic treatment of diseases where it is necessary to neutralize acid in the stomach, for example, for treating stomach and duodenal ulcers or heartburn and stomach conditions caused by excess stomach acid [F25].
DB14075ImidureaNot Available
DB14158Microcrystalline celluloseNot Available
DB14177PropylparabenPropylparaben is used in allergenic testing.
DB14199BromothalonilBromothalonil is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.
DB14212MethylparabenNot Available
DB02192Phenylethyl alcoholNot Available
DB15379Hydroxypropyl betadexNot Available
DB00168AspartameUsed as a diet supplement and sugar substitute.
DB00742MannitolUsed for the promotion of diuresis before irreversible renal failure becomes established, the reduction of intracranial pressure, the treatment of cerebral edema, and the promotion of urinary excretion of toxic substances.
DB01638SorbitolUsed as a non-stimulant laxative via an oral suspension or enema.
DB01914D-glucoseGlucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used for metabolic disorders such as hypoglycemia.[L787]
DB02772SucroseNot Available
DB03323MaltoseNot Available
DB03852EucalyptolNot Available
DB04173FructoseNot Available
DB04465LactoseNot Available
DB09287Polyethylene glycolUsed to treat and prevent constipation.
DB09344Invert sugarInvert sugar presents a large variety of uses. It can be used therapeutically for parenteral hyperalimentation[T127] or to be used as an excipient with a known effect.[L1691] Invert sugar is also approved for its use in food products as a humectant, crystallization modifier, and liquid and nutritive sweetener.[T128]
DB11195XylitolIndicated for use as a sugar substitute, and oral hygiene active ingredient.
DB12418SaccharinNot Available
DB12434SteviolbiosideNot Available
DB12942LactitolNot Available
DB14102TriethylhexanoinNot Available
DB14184CinnamaldehydeCinnamaldehyde is approved by the FDA for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.
DrugDrug NameTargetType
DB01032ProbenecidSolute carrier family 22 member 8target
DB01032ProbenecidSolute carrier family 22 member 11target
DB01032ProbenecidSerum albumincarrier
DB01032ProbenecidSolute carrier family 22 member 2transporter
DB01032ProbenecidSolute carrier family 22 member 1transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 2transporter
DB01032ProbenecidMultidrug resistance-associated protein 4transporter
DB01032ProbenecidMultidrug resistance-associated protein 5transporter
DB01032ProbenecidMonocarboxylate transporter 2transporter
DB01032ProbenecidSolute carrier family 22 member 5transporter
DB01032ProbenecidMultidrug resistance-associated protein 6transporter
DB01032ProbenecidMultidrug resistance-associated protein 1transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1A2transporter
DB01032ProbenecidMonocarboxylate transporter 1transporter
DB01032ProbenecidSodium/bile acid cotransportertransporter
DB01032ProbenecidSolute carrier family 22 member 6transporter
DB01032ProbenecidSolute carrier family 22 member 10transporter
DB01032ProbenecidSolute carrier family 22 member 8transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 1transporter
DB01032ProbenecidATP-binding cassette sub-family C member 11transporter
DB01032ProbenecidSolute carrier family 22 member 11transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1C1transporter
DB01032ProbenecidSolute carrier family 22 member 7transporter
DB01032ProbenecidSolute carrier family 22 member 6target
DB01032ProbenecidPannexin-1target
DB01032ProbenecidCytochrome P450 2C8enzyme
DB01032ProbenecidCytochrome P450 3A4enzyme
DB01032ProbenecidSolute carrier family 22 member 12transporter
DB01032ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
DB01032ProbenecidTaste receptor type 2 member 16target
DB01032ProbenecidUDP-glucuronosyltransferase 1-1enzyme
DB01032ProbenecidCytochrome P450 2C9enzyme
DB01839Propylene glycolCoagulation factor XIII A chaintarget
DB01839Propylene glycolHaloalkane dehalogenasetarget
DB01839Propylene glycolClavaminate synthase 1target
DB01839Propylene glycolLactaldehyde reductasetarget
DB01839Propylene glycolB12-independent glycerol dehydratasetarget
DB03754TromethamineCholera enterotoxin subunit Btarget
DB03754TromethamineS-adenosylmethionine decarboxylase proenzymetarget
DB03754TromethamineBiotin synthasetarget
DB03754TromethamineVascular endothelial growth factor Atarget
DB03754Tromethamine6-phosphogluconolactonasetarget
DB03754TromethamineDecorintarget
DB03754TromethamineAutolysintarget
DB03754TromethamineCytochrome c4target
DB03754TromethamineSoluble calcium-activated nucleotidase 1target
DB03754TromethamineLipoprotein NlpItarget
DB03754TromethamineDNA protection during starvation proteintarget
DB03754TromethaminePutative glucose-6-phosphate 1-epimerasetarget
DB03754TromethamineEndonuclease 8-like 1target
DB11386ChlorobutanolPotassium voltage-gated channel subfamily H member 2target
DB11590ThimerosalSerum albumincarrier
DB11590ThimerosalInositol 1,4,5-trisphosphate receptor type 1transporter
DB11590ThimerosalMethionine synthasetarget
DB11590ThimerosalCystine/glutamate transportertarget
DB11590ThimerosalSodium/potassium-transporting ATPase subunit gammatarget
DB11590ThimerosalGlutathione reductase, mitochondrialenzyme
DB11590ThimerosalGlutathione peroxidase 1enzyme
DB11590ThimerosalSuperoxide dismutase [Mn], mitochondrialenzyme
DB02192Phenylethyl alcoholParathion hydrolasetarget
DB00168AspartameTaste receptor type 1 member 2target
DB00168AspartameTransient receptor potential cation channel subfamily V member 1target
DB00168AspartameSolute carrier family 22 member 6transporter
DB00168AspartameSolute carrier family 22 member 8transporter
DB00168AspartameSolute carrier family 22 member 11transporter
DB00168AspartameTaste receptor type 1 member 3target
DB00742MannitolMultidrug resistance protein 1transporter
DB00742MannitolMannitol dehydrogenaseenzyme
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolMalate synthase Gtarget
DB01914D-glucoseHexokinase-1enzyme
DB01914D-glucoseGlucokinaseenzyme
DB01914D-glucoseSolute carrier family 2, facilitated glucose transporter member 1transporter
DB01914D-glucoseSolute carrier family 2, facilitated glucose transporter member 2transporter
DB01914D-glucoseSolute carrier family 2, facilitated glucose transporter member 3transporter
DB01914D-glucoseSolute carrier family 2, facilitated glucose transporter member 4transporter
DB01914D-glucoseSolute carrier family 2, facilitated glucose transporter member 5transporter
DB01914D-glucoseSolute carrier family 2, facilitated glucose transporter member 6transporter
DB01914D-glucoseSolute carrier family 2, facilitated glucose transporter member 7transporter
DB01914D-glucoseSolute carrier family 2, facilitated glucose transporter member 8transporter
DB01914D-glucoseSolute carrier family 2, facilitated glucose transporter member 9transporter
DB01914D-glucoseSolute carrier family 2, facilitated glucose transporter member 10transporter
DB01914D-glucoseSolute carrier family 2, facilitated glucose transporter member 11transporter
DB01914D-glucoseSolute carrier family 2, facilitated glucose transporter member 12transporter
DB01914D-glucoseSodium/glucose cotransporter 1transporter
DB01914D-glucoseSodium/glucose cotransporter 2transporter
DB02772SucroseBeta-lactamasetarget
DB02772SucroseNitric oxide synthase oxygenasetarget
DB02772SucroseLysozyme Ctarget
DB02772SucroseSeptum formation protein Maftarget
DB02772SucroseGDP-mannose 6-dehydrogenasetarget
DB02772SucroseActin, alpha skeletal muscletarget
DB02772SucroseBeta-glucosidasetarget
DB02772SucroseAmylosucrasetarget
DB02772SucroseBeta-lactamasetarget
DB02772SucroseBeta-lactamase CTX-Mtarget
DB02772SucroseHeme oxygenasetarget
DB02772SucroseCopper transport protein ATOX1target
DB02772SucrosetRNA-splicing ligase RtcB homologtarget
DB02772SucroseOrange carotenoid-binding proteintarget
DB02772SucroseSucrose porintarget
DB02772SucroseLevansucrasetarget
DB02772SucroseBeta-lactamase CTX-M-27target
DB02772SucroseTaste receptor type 1 member 2target
DB03323MaltoseCyclomaltodextrin glucanotransferasetarget
DB03323MaltoseAlpha-amylase 2Btarget
DB03323MaltoseBeta-amylasetarget
DB03323MaltoseMaltogenic alpha-amylasetarget
DB03323MaltoseMaltodextrin phosphorylasetarget
DB03323MaltoseMaltose-binding periplasmic proteintarget
DB03323MaltoseAlpha-glucosidasetarget
DB03323MaltoseMaltose binding proteintarget
DB03323MaltoseMalto-oligosyltrehalose trehalohydrolasetarget
DB04173FructoseBis(5'-adenosyl)-triphosphatasetarget
DB04173FructoseMaltoporintarget
DB04465LactoseBeta-galactosidasetarget
DB04465LactoseTetanus toxintarget
DB04465LactoseGlycosyltransferase 6 domain-containing protein 1target
DB04465LactoseGlycolipid transfer proteintarget
DB04465LactoseEnterotoxin type Btarget
DB04465LactoseSialidasetarget
DB04465LactoseHydrolasetarget
DB04465LactoseEndo-1,4-beta-xylanase Atarget
DB04465LactoseGalectin-3target
DB09344Invert sugarSolute carrier family 2, facilitated glucose transporter member 2transporter
DB09344Invert sugarSolute carrier family 2, facilitated glucose transporter member 5transporter
DB09344Invert sugarGlucokinaseenzyme
DB09344Invert sugar6-phosphofructokinaseenzyme
DB11195XylitolXylose isomerasetarget
DB11195XylitolXylose isomerasetarget
DB11195XylitolXylose isomerasetarget
DB11195XylitolXylose isomerasetarget
DB11195XylitolHyaluronate lyasetarget
DB12418SaccharinCarbonic anhydrase 3target