Ophthalmics

Name
Ophthalmics
Accession Number
DBCAT002732
Description
Not Available
Drugs
DrugDrug Description
Hydroxypropyl celluloseA cellulose ether used to treat dry eyes.
IsoflurophateFor use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
EpinastineAn H1 receptor antagonist used to prevent itching in allergic conjunctivitis.
PemirolastA medication used to treat allergies such as hay fever and allergic conjunctivitis.
ApraclonidineAn alpha adrenergic agonist used to treat raised intraocular pressure.
DiclofenamideA carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure.
BrinzolamideA carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
RanibizumabA recombinant humanized monoclonal antibody and VEGF-A antagonist used for the management of macular edema after retinal vein occlusion, age-related macular degeneration (wet), and diabetic macular edema.
CysteamineA cystine depleting agent used to treat nephrotic cystinosis.
AfliberceptA vascular endothelial growth factor (VEGF) inhibitor used to treat Neovascular (Wet) Age-Related Macular Degeneration (AMD), various types of macular edema and diabetic retinopathy.
OcriplasminA proteolytic enzyme used to treat symptomatic vitreomacular adhesion by dissolving the protein matrix responsible for the adhesion between the vitreous and macula.
TafluprostAn ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
TravoprostA prostaglandin analog used in the treatment of elevated intraocular pressure due to open angle glaucoma or ocular hypertension.
DapiprazoleUsed in the treatment of iatrogenically induced mydriasis produced by adrenergic (phenylephrine) or parasympatholytic (tropicamide) agents used in certain eye examinations.
DipivefrinA prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma.
Drugs & Drug Targets
DrugTargetType
IsoflurophateCholinesterasetarget
IsoflurophateAcetylcholinesterasetarget
IsoflurophateCholinesteraseenzyme
IsoflurophateSerum albumincarrier
IsoflurophateSerotransferrintarget
EpinastineHistamine H1 receptortarget
EpinastineHistamine H2 receptortarget
EpinastineAlpha-1A adrenergic receptortarget
EpinastineAlpha-2A adrenergic receptortarget
Epinastine5-hydroxytryptamine receptor 2Atarget
Epinastine5-hydroxytryptamine receptor 7target
EpinastineP-glycoprotein 1transporter
EpinastineCytochrome P450 2B6enzyme
EpinastineCytochrome P450 2D6enzyme
EpinastineCytochrome P450 3A4enzyme
ApraclonidineAlpha-2A adrenergic receptortarget
ApraclonidineAlpha-1A adrenergic receptortarget
ApraclonidineAlpha-2B adrenergic receptortarget
DiclofenamideCarbonic anhydrase 1target
DiclofenamideCarbonic anhydrase 4target
DiclofenamideCarbonic anhydrase 2target
DiclofenamideCarbonic anhydrase 7target
DiclofenamideCarbonic anhydrase 3target
BrinzolamideCarbonic anhydrase 1target
BrinzolamideCarbonic anhydrase 2target
BrinzolamideCytochrome P450 3A4enzyme
BrinzolamideCarbonic anhydrase 5A, mitochondrialtarget
BrinzolamideCarbonic anhydrase 4target
BrinzolamideCarbonic anhydrase 3target
RanibizumabVascular endothelial growth factor Atarget
CysteamineSomatostatintarget
CysteamineNeuropeptide Y receptor type 2target
CysteamineCystinetarget
CysteamineMyeloperoxidaseenzyme
AfliberceptVascular endothelial growth factor Atarget
AfliberceptPlacenta growth factortarget
AfliberceptVascular endothelial growth factor Btarget
OcriplasminAlpha-2-macroglobulintarget
OcriplasminAlpha-2-antiplasmintarget
OcriplasminFibronectintarget
TafluprostProstaglandin F2-alpha receptortarget
TafluprostProstaglandin G/H synthase 2enzyme
TravoprostProstaglandin F2-alpha receptortarget
DapiprazoleAlpha-1A adrenergic receptortarget
DapiprazoleAlpha-1D adrenergic receptortarget
DapiprazoleAlpha-1B adrenergic receptortarget
DipivefrinAlpha-2A adrenergic receptortarget
DipivefrinCholinesterasetarget
DipivefrinBeta-2 adrenergic receptortarget
DipivefrinAlpha-1A adrenergic receptortarget
DipivefrinAcetylcholinesterasetarget