- Antituberculosis Agents
- Accession Number
- DBCAT003667 (DBCAT000586)
Drugs used in the treatment of tuberculosis. They are divided into two main classes: "first-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.
Drug Drug Description Aminosalicylic acid An aminosalicylate drug used to induce remission in ulcerative colitis. Cycloserine A broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI). Capreomycin An aminoglycoside antibiotic used as an adjunct drug in tuberculosis. Ethionamide A second line antitubercular agent used to treat tuberculosis when other treatments have failed. Amprenavir A protease inhibitor used to treat HIV infection. Rifapentine An antibiotic agent used in the treatment of pulmonary tuberculosis. Sparfloxacin For the treatment of adults with the following infections caused by susceptible strains microorganisms: community-acquired pneumonia (caused by Chlamydia pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, or Streptococcus... Rifalazil Investigated for use/treatment in atherosclerosis, bacterial infection, and peripheral vascular disease. Pretomanid Part of a three-drug regimen used for the treatment of extensively drug-resistant and multidrug-resistant pulmonary tuberculosis. Viomycin Viomycin is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis. Bedaquiline A diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB). Enviomycin Cyclic basic peptide related to viomycin. It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin. Thiosulfuric acid A sulfur donor used for sequential use with sodium nitrite for the reversal of acute cyanide poisoning that is judged to be life-threatening. Pazufloxacin Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol). Protionamide Prothionamide has been used in trials studying the treatment of MDR-TB and HIV Infections. Amithiozone Amithiozone has been used in trials studying the treatment of Mycobacterium Avium-intracellulare Infection. Ethambutol An antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB). Pyrazinamide An antituberculosis agent used as a component of tuberculosis (TB) treatment. Rifabutin An antibiotic used to treat mycobacterium avium complex disease in patients with HIV. Isoniazid An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis. Rifampicin An antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis. Mycophenolate mofetil An inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants. Mycophenolic acid An immunosuppressant used to prevent organ transplant rejections.
- Drugs & Drug Targets