Nepidermin

Identification

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Name

Nepidermin

Accession Number

DB14145

Type

Biotech

Groups

Experimental

Description

Not Available

Synonyms

• Beta-urogastrone
• Epidermal growth factor (human)
• Epidermal growth factor biosynthetic human
• Epidermal growth factor human
• H-EGF
• Human EGF
• Human epidermal growth factor
• Human urogastrone
• Nepidermina
• Népidermine
• Nepiderminum
• Recombinant human epidermal growth factor
• rhEGF
• Urogastrone

Over the Counter Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End
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EASYDEW DW EGF Derma Needle 3000 Shot	Solution	0.000045 mg/45mg	Topical	Dn Company Co.,Ltd.	2018-03-01	Not applicable
Easydew EX Repair Control Repair Control Egf	Liquid	0.0002 g/20mL	Topical	Dn Company Co.,Ltd.	2018-02-01	Not applicable
EASYDEW EX REPAIR CONTROL REPAIR CONTROL EGF 3mL	Liquid	0.03 mg/3mL	Topical	Dn Company Co.,Ltd.	2018-07-01	Not applicable

Additional Data Available

Application Number
Application Number
A unique ID assigned by the FDA when a product is submitted for approval by the labeller.
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Product Code
Product Code
A governmentally-recognized ID which uniquely identifies the product within its regulatory market.
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Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
ARTEMES 3R Effect Hyaluronic Ampoule	Nepidermin (0.05 mg/5mL) + Adenosine (0.002 g/5mL) + Nicotinamide (0.10 g/5mL)	Liquid	Topical	Dn Company Co.,Ltd.	2019-03-01	Not applicable
Artemes 3R effect hyaluronic mask	Nepidermin (0.33 mg/33g) + Adenosine (0.01 g/33g) + Nicotinamide (0.66 g/33g)	Patch	Topical	Dn Company Co.,Ltd.	2019-03-01	Not applicable
Cosmeceutical Mask Pack	Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)	Patch	Topical	YBK Investment, INC	2013-10-21	2013-10-29
Cosmeceutical Mask Pack	Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)	Patch	Topical	YBK Investment, INC	2013-10-21	Not applicable
Dermaheal Cosmeceutical Mask Pack Plus	Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)	Patch	Topical	YBK Investment, INC	2013-10-21	Not applicable
EASYDEW DW EGF Derma Oneshot Ampoule	Nepidermin (0.000001 mg/1.2mL) + Adenosine (0.00048 mg/1.2mL) + Nicotinamide (0.024 mg/1.2mL)	Liquid	Topical	Dn Company Co.,Ltd.	2018-03-01	Not applicable
Easydew EX Repair Control Active Soothing Serum	Nepidermin (0.00012 g/40mL) + Adenosine (0.016 g/40mL) + Nicotinamide (0.8 g/40mL)	Cream	Topical	Dn Company Co.,Ltd.	2018-02-01	Not applicable
Easydew EX Repair Control Renewal Moisture	Nepidermin (0.0001 g/50mL) + Adenosine (0.02 g/50mL) + Nicotinamide (1.0 g/50mL)	Cream	Topical	Dn Company Co.,Ltd.	2018-02-01	Not applicable
Le-Blen EGF Serum	Nepidermin (0.54 g/56.7g) + Sodium hyaluronate (0.4 g/56.7g)	Lotion	Topical	LeBlen Beauty Inc	2018-04-24	Not applicable

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
ARTEMES 3R Effect Hyaluronic Ampoule	Nepidermin (0.05 mg/5mL) + Adenosine (0.002 g/5mL) + Nicotinamide (0.10 g/5mL)	Liquid	Topical	Dn Company Co.,Ltd.	2019-03-01	Not applicable
Artemes 3R effect hyaluronic mask	Nepidermin (0.33 mg/33g) + Adenosine (0.01 g/33g) + Nicotinamide (0.66 g/33g)	Patch	Topical	Dn Company Co.,Ltd.	2019-03-01	Not applicable
Cosmeceutical Mask Pack	Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)	Patch	Topical	YBK Investment, INC	2013-10-21	Not applicable
Cosmeceutical Mask Pack	Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)	Patch	Topical	YBK Investment, INC	2013-10-21	2013-10-29
Dermaheal Cosmeceutical Mask Pack Plus	Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)	Patch	Topical	YBK Investment, INC	2013-10-21	Not applicable
EASYDEW DW EGF Derma Needle 3000 Shot	Nepidermin (0.000045 mg/45mg)	Solution	Topical	Dn Company Co.,Ltd.	2018-03-01	Not applicable
EASYDEW DW EGF Derma Oneshot Ampoule	Nepidermin (0.000001 mg/1.2mL) + Adenosine (0.00048 mg/1.2mL) + Nicotinamide (0.024 mg/1.2mL)	Liquid	Topical	Dn Company Co.,Ltd.	2018-03-01	Not applicable
Easydew EX Repair Control Active Soothing Serum	Nepidermin (0.00012 g/40mL) + Adenosine (0.016 g/40mL) + Nicotinamide (0.8 g/40mL)	Cream	Topical	Dn Company Co.,Ltd.	2018-02-01	Not applicable
Easydew EX Repair Control Renewal Moisture	Nepidermin (0.0001 g/50mL) + Adenosine (0.02 g/50mL) + Nicotinamide (1.0 g/50mL)	Cream	Topical	Dn Company Co.,Ltd.	2018-02-01	Not applicable
Easydew EX Repair Control Repair Control Egf	Nepidermin (0.0002 g/20mL)	Liquid	Topical	Dn Company Co.,Ltd.	2018-02-01	Not applicable

International/Other Brands

Easyef / Genesoft / Kang He Su / Regen-D

Categories

• Amino Acids, Peptides, and Proteins
• Biological Factors
• EGF Family of Proteins
• Gastrointestinal Hormones
• Hormones
• Hormones, Hormone Substitutes, and Hormone Antagonists
• Intercellular Signaling Peptides and Proteins
• Peptides
• Proteins

UNII

TZK30RF92W

CAS number

62253-63-8

Pharmacology

Indication

Not Available

Pharmacodynamics

Not Available

Mechanism of action

Not Available

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Additional Data Available

Adverse Effects

Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.

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Additional Data Available

Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available

Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

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Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism

Not Available

Route of elimination

Not Available

Half life

Not Available

Clearance

Not Available

Toxicity

Not Available

Affected organisms

Not Available

Pathways

Not Available

Pharmacogenomic Effects/ADRs

Not Available

Interactions

Drug Interactions

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

Not Available

Food Interactions

Not Available

References

General References

Not Available

External Links

Wikipedia

Nepidermin

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count
1, 2	Recruiting	Treatment	Advanced Head and Neck Squamous Cell Carcinoma / ALK Gene Mutation / EGFR Gene Mutations / Lung Non-Small Cell Carcinoma / Metastatic Lung Non-Small Cell Carcinoma / PD-L1 positive / Recurrent Head and Neck Squamous Cell Carcinoma / Recurrent Non-Small Cell Lung Carcinoma / Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 / Stage III Lung Cancer AJCC v8 / Stage IIIA Lung Cancer AJCC v8 / Stage IIIB Lung Cancer AJCC v8 / Stage IIIb Non-small Cell Lung Cancer / Stage IIIC Lung Cancer AJCC v8 / Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 / Stage IV Lung Cancer AJCC v8 / Stage IV Non-Small Cell Lung Cancer / Stage IVA Lung Cancer AJCC v8 / Stage IVB Lung Cancer AJCC v8 / Unresectable Lung Non-Small Cell Carcinoma	1
2	Active Not Recruiting	Treatment	Colorectal Cancers	1
2	Completed	Prevention	Oral Mucositis	1
2	Recruiting	Treatment	HER2/Neu+ Uterine Serous Carcinoma	1
3	Completed	Treatment	Diabetic Foot Ulcer Patients With Uncontrolled Diabetes Mellitus	1
3	Not Yet Recruiting	Treatment	Diabetic Foot Ulcers (DFU) / Epidermal Growth Factor	1
3	Unknown Status	Treatment	Stomatitis	1
Not Available	Recruiting	Prevention	Drug-Related Side Effects and Adverse Reactions / Epidermal Growth Factor	1
Not Available	Recruiting	Treatment	Drug-Related Side Effects and Adverse Reactions / Epidermal Growth Factor	1

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage forms

Form	Route	Strength
Patch	Topical
Solution	Topical	0.000045 mg/45mg
Liquid	Topical
Cream	Topical
Liquid	Topical	0.0002 g/20mL
Liquid	Topical	0.03 mg/3mL
Lotion	Topical

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Taxonomy

Classification

Not classified

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Drug created on June 27, 2018 14:17 / Updated on December 02, 2019 10:10