Hormones
- Name
- Hormones
- Accession Number
- DBCAT000056
- Description
Chemical substances having a specific regulatory effect on the activity of a certain organ or organs. The term was originally applied to substances secreted by various ENDOCRINE GLANDS and transported in the bloodstream to the target organs. It is sometimes extended to include those substances that are not produced by the endocrine glands but that have similar effects.
- Drugs
Drug Drug Description Leuprolide A peptide-based GnRH receptor superagonist used for the palliative treatment of prostate cancer, uterine leiomyomata, endometriosis, and central precocious puberty. Sermorelin For the treatment of dwarfism, prevention of HIV-induced weight loss Goserelin A synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary. Salmon calcitonin A synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease. Thyrotropin alfa A recombinant form of thyroid stimulating hormone used in diagnostic testing for thyroid cancer and alongside radioactive agents to destroy thyroid tissue. Insulin human A recombinant form of human insulin used to control hyperglycemia in diabetes mellitus. Menotropins A purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility. Desmopressin A synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia. Glucagon A form of recombinant glucagon used to treat hypoglycemia in diabetes mellitus and as a part of gastrointestinal imaging procedures. Insulin lispro A modified form of fast-acting insulin used to control hyperglycemia in diabetes mellitus. Insulin glargine A modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus. Cetrorelix A synthetic peptide antagonist of gonadotropin releasing hormone used to prevent luteinizing hormone surges in women undergoing assisted reproduction therapy. Somatotropin A form of recombinant human growth hormone used to treat dwarfism, growth hormone deficiency, and acromegaly as well as to prevent weight loss in HIV patients. Follitropin A form of recombinant human follicle stimulating hormone used to stimulate follicle development in women with primary ovarian hypogonadism and in men with hypogonadotropic hypogonadism. Vasopressin A peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy. Insulin pork A purified form of porcine insulin used to control hyperglycemia in diabetes mellitus. Pegvisomant A growth hormone receptor antagonist used to treat acromegaly. Felypressin For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential. Urofollitropin A form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure. Oxytocin A recombinant hormone used to induce or strengthen uterine contractions in pregnant women to aid in labor and delivery or to control postpartum bleeding. Pentagastrin A gastrin-like molecule used as a diagnostic aid for the evaluation of gastric acid secretory function, gastric hypersecretion, and Zollinger-Ellison tumors. Diflorasone A topical corticosteroid used to treat the symptoms of various inflammatory skin conditions that cause erythema, pruritus, and discomfort. Alclometasone A topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses. Medrysone A topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions. Diethylstilbestrol Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery. Chlorotrianisene Used to treat symptoms of menopause, deficiencies in ovary function (including underdevelopment of female sexual characteristics and some types of infertility), and in rare cases, prostate cancer. Chlorotrianisene may also... Liothyronine A thyroid hormone replacement therapy used to treat hypothyroidism, to suppress TSH, and to help in the diagnosis of hyperthyroidism. Conjugated estrogens A mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis. Amcinonide A topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses. Desogestrel A synthetic progestin used in contraception, often in combination with ethinyl estradiol. Fluorometholone An ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye. Dydrogesterone Used to treat irregular duration of cycles and irregular occurrence and duration of periods caused by progesterone deficiency. Also used to prevent natural abortion in patients who have a history... Beclomethasone dipropionate An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks. Progesterone A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. Betamethasone A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders. Levothyroxine A synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. Dronabinol A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. Dextrothyroxine A thyroid hormone used to treat hyperlipidemia. Desoximetasone A glucocorticoid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Fluocinolone acetonide A corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye. Medroxyprogesterone acetate A progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty. Triamcinolone A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues. Oxandrolone An androgenic hormone used to treat muscle loss from prolonged corticosteroid treatment and to treat bone pain associated with osteoporosis. Testosterone A hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause. Prednisone A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases. Gonadorelin A synthetic GnRH used to test the function of gonadotropes and the pituitary. Estrone An estrogen used to treat perimenopausal and postmenopausal symptoms. Flumethasone A corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions. Nafarelin A gonadotropin releasing hormone agonist used to treat central precocious puberty. Fludrocortisone A mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome. Hydrocortisone A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders. Estradiol An estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate. Clocortolone A corticosteroid used to treat inflammatory and pruritic dermatoses of the scalp. Flurandrenolide A corticosteroid used to treat corticosteroid-responsive dermatoses. Prednisolone A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers. Dienestrol A non steroidal estrogen used to treat atrophic vaginitis and kraurosis vulvae. Rimexolone A glucocorticoid used to treat inflammation of the eye. Fulvestrant An estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-. Methylprednisolone A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases. Ethinylestradiol An estradiol used as a contraceptive. Nandrolone phenpropionate For the treatment of refractory deficient red cell production anemias, breast carcinoma, hereditary angioedema, antithrombin III deficiency, fibrinogen excess, growth failure and Turner's syndrome. It is also indicated in the... Clobetasol propionate A corticosteroid used to treat corticosteroid-responsive dermatoses and plaque psoriasis. Fluocinonide A high potency corticosteroid commonly used topically for a number of inflammatory skin conditions. Melatonin An endogenous hormone produced by the pineal gland that regulates sleep-wake cycles and when provided exogenously has beneficial effects on sleep-onset latency; available as an over-the-counter supplement. Trilostane Used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible. Prednicarbate A medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions. Desoxycorticosterone pivalate Examined for treatment of adrenocortical insufficiency especially in multiple sclerosis, congenital cerebral palsy, polyarteritis nodosa, and rheumatoid arthritis. Currently only approved in treating cats and dogs for the treatment of... Fluoxymesterone A synthetic androgenic anabolic steroid that used in the treatment of hypogonadism and delayed puberty in males, as well as breast neoplasms in women. Estramustine An antineoplastic agent used for the management of metastatic and/or progressive prostate cancer in palliative setting. Budesonide A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis. Dexamethasone A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. Sitagliptin An oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus. Exenatide A GLP-1 agonist used in the management of type 2 diabetes mellitus. Pramlintide An amylin analog used for the management of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy. Carbetocin An oxytocin agent used to control postpartum hemorrhage and bleeding after giving birth. Tetracosactide A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. Corticotropin A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. Insulin aspart A rapid-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin detemir A long-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin glulisine A short-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Mestranol A synthetic estradiol found in oral contraceptive pills for contraception and the treatment of other conditions in the female reproductive system, such as dysmenorrhea and dysfunctional uterine bleeding. Cortisone acetate A steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones. Paramethasone For the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary... Ciclesonide A glucocorticoid used in the symptomatic relief of nasal symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents. Testosterone propionate A slow-release anabolic steroid no longer used commonly for the treatment of androgen deficiency or promotion of anabolic effects on muscles. Allylestrenol Allylestrenol was designed to be used for miscarriage prevention, prevention of premature labour and has been investigated for possible use in men for treatment for benign prostatic hyperplasia. 19-norandrostenedione The claim that supplemental 19-norandrostenedione has anabolic effects is unsubstantiated. 5-androstenedione 5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its... Bolasterone Not Available 1-Testosterone 1-Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring. 4-Hydroxytestosterone 4-Hydroxytestosterone is testosterone substituted with a hydroxy group on the fourth carbon atom. It is an anabolic steroid with no therapeutic indications, which is prohibited from use in sports by... Ethylestrenol An anabolic steroid with some progestational activity and little androgenic effect. [PubChem] Clostebol Not Available Androstenediol Androstenediol is an intermediate in testosterone biosynthesis, found in the testis or the adrenal glands. Androstenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted... Androstenedione A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as... Boldenone Boldenone is an anabolic steroid developed for veterinary use, mostly for treatment of horses. It is not indicated for use in humans in the US and is only available through... Bolandiol Not Available Calusterone An anabolic steroid which can theoretically aid in restauration and buildup of certain tissues, especially muscle. It is similar to synthetic testosterone and is still in early investigation. It was... Liotrix May be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic... Genistein Currently Genistein is being studied in clinical trials as a treatment for prostate cancer. Prasterone A steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy. Equilin For the treatment of moderate to severe vasomotor symptoms associated with the menopause, atrophic vaginitis, osteoporosis, hypoestrogenism due to hypogonadism, castration, primary ovarian failure, breast cancer (for palliation only), and... EM-1745 Not Available 2-Methoxyestradiol For the treatment of breast cancer and inflammatory diseases such as rheumatoid arthritis. Terlipressin Commonly used to stop bleeding of varices in the food pipe (oesophagus). Pregnenolone A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. Stanolone A potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure... Equilenin Equilenin is an estrogenic steroid produced by horses. It has a total of five double bonds in the A- and B-ring. High concentration of equilenin is found in the urine... Afimoxifene For the potential treatment of menstrual-cycle related mastalgia, fibrocystic breast disease, breast disease, gynecomastia and Keloid scarring. Estriol Used as a test to determine the general health of an unborn fetus. Estrone sulfate An estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders. Quinestrol Used in hormone replacement therapy, treating symptoms of menopause such as hot flashes. Also used to treat breast and prostate cancer. Aldosterone A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. Corticosterone An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437) Oleoyl-estrone For the treatment of obesity. Vapreotide For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea. Nesiritide A recombinant natriuretic peptide used for the treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity. Thymalfasin Indicated as an adjuvant for influenza vaccine in elderly patients and as an adjuvant for both influenza and hepatitis B vaccines in chronic hemodialysis patients who failed to achieve adequate... G17DT Intended for the treatment of various forms of cancer. Ularitide Investigated for use/treatment in congestive heart failure. Abaloparatide A parathyroid hormone-related protein (PTHrP) analog used for the treatment of osteoporosis in postmenopausal women with a high risk of fracture. Leptin Investigated for use/treatment in lipodystrophy and obesity. 16-Bromoepiandrosterone Investigated for use/treatment in cystic fibrosis, HIV infection, hepatitis (viral, B), and malaria. NN344 Investigated for use/treatment in diabetes mellitus type 1 and 2. HE3286 For the treatment of rheumatoid arthritis and type 2 diabetes. Anecortave acetate Investigated for use/treatment in glaucoma and macular degeneration. Corticorelin Investigated for use/treatment in brain cancer and neurologic disorders. NCX 1022 Investigated for use/treatment in atopic dermatitis. Etiprednol dicloacetate Investigated for use/treatment in asthma and crohn's disease. Prasterone sulfate Investigated for use/treatment in asthma and burns and burn infections. NBI-6024 Investigated for use/treatment in diabetes mellitus type 1 and pediatric indications. Parathyroid hormone An analog of human parathyroid hormone (PTH) used to treat hypocalcemia caused by hypoparathyroidism. Trestolone Investigated for use/treatment in contraception and male hormonal deficiencies/abnormalities. Rimonabant For use in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m2, or patients wih a BMI greater than 27 kg/m2 with associated... Istaroxime Investigated for use/treatment in heart disease. Alogliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus. Fluasterone Investigated for use/treatment in psoriasis and psoriatic disorders, hyperlipidemia, metabolic disease, cancer/tumors (unspecified), and obesity. Aviptadil Not Annotated Teriparatide A recombinant parathyroid hormone used for the treatment of osteoporosis. Saxagliptin An DPP-4 inhibitor used for the management of type 2 diabetes mellitus. Oxymetholone An anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias. Anamorelin Investigated for use/treatment in cachexia and anorexia. Liraglutide A GLP-1 analog used in the management of type 2 diabetes mellitus and prevention of cardiovascular complications associated with diabetes. Pasireotide A somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate. Methyltestosterone A synthetic anabolic steroid used for the replacement therapy in conditions associated with testosterone deficiencies in males, such as hypogonadism, and treatment of advancing inoperable metastatic breast cancer in females. Stanozolol Stanozolol is a synthetic anabolic steroid with therapeutic uses in treating C1-inhibitor deficient hereditary angioedema. C1-inhibitor is a protease that inhibits the complement system (part of the innate immune system),... Buserelin A LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females. Gestodene Gestodene is a progestogen hormonal contraceptive. Products containing gestoden include Meliane, which contains 20 mcg of ethinylestradiol and 75 mcg of gestodene; and Gynera, which contains 30 mcg of ethinylestradiol... Saralasin Not Annotated Desoxycorticosterone acetate Not Annotated Difluprednate A topical corticosteroid used for the symptomatic treatment of inflammation and pain associated with ocular surgery. Ganirelix A GnRH antagonist used in assisted reproduction in women undergoing controlled ovarian hyperstimulation to control ovulation by inhibiting the premature LH surges. Histrelin A GnRH agonist found in subcutaneous implants used for the treatment of pediatric patients with central precocious puberty and the palliative treatment of advanced prostate cancer. Hydroxyprogesterone caproate A synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth. Lanreotide A somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly. Triptorelin A GnRH agonist indicated for the palliative treatment of advanced prostate cancer. 2-Hydroxyestradiol 2-Hydroxyestradiol is classified as an endogenous steroid, catechol estrogen, and metabolite of estradiol. It is also a positional isomer of estriol. Hexestrol A synthetic estrogen that has been used as a hormonal antineoplastic agent. Testosterone succinate Not Available Nandrolone decanoate An anabolic steroid indicated for the management of the anemia of renal insufficiency by increasing hemoglobin and red cell mass. Cholecystokinin For use as a diagnostic aid for evaluation of gallbladder disorders. It is also used in conjunction with secretin in pancreatic insufficiency . Tesamorelin A growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy. Linagliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. Teduglutide A glucagon-like peptide-2 (GLP-2) analog used to treat patients with Short Bowel Syndrome (SBS) who require parenteral nutritional support. Formestane For the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Fluocortolone Fluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders. Albiglutide A GLP-1 agonist used to manage type 2 diabetes mellitus. Dulaglutide A GLP-1 agonist used to manage type 2 diabetes mellitus. Metreleptin A leptin analogue used as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy. Atosiban An inhibitor of oxytocin and vasopressin used to delay imminent preterm birth in pregnant adult women displaying specific clinical observations. Corifollitropin alfa A FSH analogue indicated for Controlled Ovarian Stimulation (COS) in combination with a GnRH antagonist for the development of multiple follicles in women participating in an Assisted Reproductive Technology (ART) program. Corticorelin ovine triflutate A synthetic corticotropin-releasing hormone used for diagnostic purposes in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome. Tibolone For the relief of post-menopausal symptoms and for the prevention of osteoporosis . Tixocortol A corticosteroid used for the symptomatic treatment of rhinitis, pharyngitis, and ulcerative colitis. Difluocortolone A topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis. Somatrem A recombinant growth hormone used to treat adult growth hormone deficiency and treat disrupted growth in children due to growth hormone insufficiency or deficiency, turner's syndrome, chronic renal failure, and small stature for gestational age. Somatostatin A naturally-occurring peptide hormone used for the symptomatic treatment of acute bleeding from esophageal varices. Dienogest An oral progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol. Chorionic Gonadotropin (Human) A naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women. Sincalide A diagnostic agent used to stimulate gallbladder contraction or pancreatic secretion during diagnostic tests, and accelerate fluoroscopy and x-ray examination of the intestinal tract. Synthetic Conjugated Estrogens, A A mixture of estrogens used to treat a variety of postmenopausal symptoms, including vaginal atrophy and dyspareunia. Synthetic Conjugated Estrogens, B A mixture of estrogens used to treat a variety of postmenopausal symptoms, including vaginal dryness. Polyestradiol phosphate Polymeric phosphoric acid ester of estradiol. Fluprednisolone A synthetic glucocorticoid with anti-inflammatory properties. Protirelin A synthetic analogue of thyrotropin-releasing hormone that has been used during diagnostic tests to evaluate function of the thyroid gland. Secretin porcine A secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts. Insulin degludec A long acting insulin used to treat hyperglycemia caused by type 1 and 2 diabetes mellitus. Altrenogest Altrenogest, also known as allyltrenbolone, is a steroidal progestin that is widely used in veterinary medicine to suppress estrus in animals. Mibolerone Mibolerone is a potent anabolic steroid which is both higher affinity and more selective for the androgen receptor than metribolone. Zeranol Zeranol is a non-steroidal estrogen agonist. It is a mycotoxin, derived from fungi in the Fusarium family, and may be found as a contaminant in fungus-infected crops. It is 3-4x... Dexamethasone isonicotinate Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention. Deslorelin Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist also known as an LHRH agonist. It stops the production of sex hormones. Melengestrol Melengestrol is a steroidal progestin and antineoplastic agent which was never marketed. An acylated derivative, melengestrol acetate, is used as a growth promoter in animals. Trenbolone Trenbolone, also known as trienolone or trienbolone, is a steroid used on livestock to increase muscle growth and appetite. To increase its effective half-life, trenbolone is administered as a prodrug... Insulin peglispro Not Annotated Gestrinone Endometriosis with or without accompanying sterility. Treatment is limited to a single course of 6 months duration per lifetime [L1699, L1700]. Bremelanotide Bremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of... Equol Equol has been used in trials studying the treatment of Breast Cancer. Setmelanotide Setmelanotide has been investigated for the treatment of obesity. Bombesin Bombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and... Clobetasol Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids. Cenderitide Cenderitide is under investigation for the treatment of ST Elevation (STEMI) Myocardial Infarction of Anterior Wall. Angiotensin II A peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock. Lenomorelin Lenomorelin has been investigated for the treatment and basic science of Cancer, Alcoholism, Metabolism, Hypopituitarism, and Frailty Syndrome, among others. Vosoritide Vosoritide has been used in trials studying the treatment of Achondroplasia. Thymopentin Thymopentin has been used in trials studying the treatment and prevention of HIV Infections and Hepatocellular Carcinoma. Thymosin beta-4 Thymosin Beta 4 has been investigated for the treatment of STEMI, Dry Eye, Diabetes, Pressure Ulcers, and Dry Eye Syndrome, among others. Anecortave Anecortave is under investigation in clinical trial NCT00691717 (Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension). TT-232 Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma). Secoisolariciresinol Secoisolariciresinol has been used in trials studying the prevention of Breast Cancer. Atamestane Atamestane has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasms, Hormone-Dependent. Estetrol Estetrol has been investigated for the treatment and basic science of Prostatic Neoplasms. Promestriene Promestriene has been used in trials studying the prevention of Hypospadias. Selepressin Selepressin has been used in trials studying the treatment of Septic Shock. Clascoterone Clascoterone has been used in trials studying the treatment of Acne Vulgaris. Pentetreotide Pentetreotide has been used in trials studying the diagnostic of cushing syndrome. 3,5-diiodothyropropionic acid DITPA has been investigated in Congestive Heart Failure. Ibipinabant Ibipinabant has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes. Zoptarelin doxorubicin Zoptarelin doxorubicin has been used in trials studying the treatment of Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, and Urothelial Carcinoma, among others. Somatoprim Somatoprim is under investigation for the treatment of Acromegaly. Norethandrolone Norethandrolone is under investigation in clinical trial NCT00700544 (Treatment Outcome in Elderly Patients). Pancreatic Polypeptide Pancreatic Polypeptide has been investigated for the treatment of Diabetes Mellitus, Type 1. Urocortin-2 Urocortin 2 has been investigated for the basic science of Heart Failure and Cardiovascular Disease. Surinabant Surinabant has been investigated for the treatment of Smoking Cessation. Clobetasone A corticosteroid used to treat dry eyes, eczema, and dermatitis. Nandrolone Nandrolone, also known as 19-nortestosterone or 19-norandrostenolone, is a synthetic anabolic-androgenic steroid (AAS) derived from testosterone. Daidzein Not Annotated Oxabolone cipionate Used as a performance enhancing drug illicitly in athletes. Alsactide Not Annotated Epimestrol Not Annotated Moxestrol Not Annotated Ornipressin Not Annotated Angiotensinamide Not Annotated Metandienone Not Annotated Mesterolone Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT). It is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is... Flumedroxone Not Annotated Metenolone Not Annotated Elcatonin Not Annotated Demoxytocin Not Annotated Semaglutide A glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus. Testosterone cypionate An androgen used to treat low or absent testosterone. Testosterone enanthate An androgen used to treat low or absent testosterone. Testosterone undecanoate An androgen used to treat low or absent testosterone. Testosterone enantate benzilic acid hydrazone Not Annotated Estradiol benzoate Estradiol benzoate is not currently available in any FDA or Health Canada approved products. Estradiol cypionate An estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism. Estradiol dienanthate Estradiol dienanthate is not currently available in any FDA or Health Canada approved products. Estradiol valerate An estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception. Trestolone acetate Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed. It is an androgen ester – specifically, the C17 acetate... Taspoglutide Taspoglutide is a pharmaceutical drug, a glucagon-like peptide-1 agonist (GLP-1 agonist), under investigation for treatment of type 2 diabetes being codeveloped by Ipsen and Roche. In September 2010 Roche halted... Palmidrol A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food... Nepidermin Not Annotated Hydrocortisone aceponate For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many... Hydrocortisone acetate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis. Hydrocortisone butyrate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Hydrocortisone cypionate For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many... Hydrocortisone phosphate For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many... Hydrocortisone probutate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Hydrocortisone valerate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Hydrocortisone succinate A corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders. Secretin human A secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts. Prednisolone phosphate A corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions. Prednisolone hemisuccinate Not Annotated Fluprednidene acetate Fluprednidene acetate is a corticosteroid. It has anti-inflammatory and anti-allergic properties. Boldenone undecylenate Not Annotated Lypressin Not Annotated Methylprednisolone hemisuccinate A water soluble corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders. Prednisone acetate Not Annotated Clocortolone acetate Not Annotated Melengestrol acetate A 6-methyl progesterone acetate with reported glucocorticoid activity and effect on estrus. Trenbolone acetate Not Annotated Betamethasone phosphate A fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions. Estradiol sulfamate Investigated for use/treatment in endometriosis. Epitestosterone Epitestosterone is the 17-alpha isomer of testosterone, derived from pregnenolone via the delta5-steroid pathway, and via 5-androstene-3-beta,17-alpha-diol. Epitestosterone acts as an antiandrogen in various target tissues. The ratio between testosterone/epitestosterone... Tiratricol A metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome. Indium In-111 pentetreotide Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome. Plecanatide A laxative used to treat chronic idiopathic constipation and IBS with constipation. Peptide YY (3-36) Investigated for use/treatment in metabolic disease and obesity. Luteinizing hormone Not Annotated Cortisone A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to... Brexanolone Brexanolone is a synthetic neuroactive steroid gamma-aminobutyric acid A (GABA(a)) receptor positive modulator indicated for the treatment of postpartum depression (PPD) in adult women [FDA Label][A176080, A176083, F4063, F4066, F4072]. Procalcitonin Procalcitonin is under investigation in clinical trial NCT03440060 (Procalcitonin-guided Antibiotic Therapy During Severe Exacerbation of COPD). Somapacitan Somapacitan is under investigation in clinical trial NCT01706783 (A Trial Investigating the Safety, Tolerability, Availability and Distribution in the Body of Once-weekly Long-acting Growth Hormone (Somapacitan) Compared to Once Daily... Somatropin pegol Somatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083). Gastric inhibitory polypeptide Gastric inhibitory polypeptide is under investigation in clinical trial NCT03081676 (The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without Sulphonylurea). Thyrotropin Thyrotropin is under investigation in clinical trial NCT01348191 (Detection of Thyrotrophin Receptor in Human Myometrium). Biochanin A Biochanin A is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.). Formononetin Formononetin is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.). rGLP-1 Investigated for use/treatment in congestive heart failure and diabetes mellitus type 2. Taranabant Investigated for use/treatment in obesity. Angiotensin 1-7 TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities. Ajulemic acid Ajulemic acid has been used in trials studying the treatment of Cystic Fibrosis, Dermatomyositis, and Diffuse Cutaneous Systemic Sclerosis. Aclerastide Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic. Pirnabine Pirnabine has been used in trials studying the treatment of Chronic Idiopathic Constipation. Albusomatropin Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency. Halometasone Not Annotated BPI-3016 BPI-3016 is under investigation in clinical trial NCT03188848 (Dose Escalating Study of BPI-3016 in Healthy Subjects). Tirzepatide Tirzepatide is under investigation in clinical trial NCT03311724 (A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes). Atrial natriuretic peptide Not Annotated Tetrahydrogestrinone Not Available Bisphenol A Not Available ICI-164384 Not Available Tetraiodothyroacetic acid Not Available Fluoroestradiol F-18 A radiolabeled analog of estradiol used as a contrast agent in the PET imaging of estrogen receptor-positive breast cancer lesions. - Drugs & Drug Targets