Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
DrugDrug NameDrug Indication
DB00001LepirudinFor the treatment of heparin-induced thrombocytopenia
DB00004Denileukin diftitoxFor treatment of cutaneous T-cell lymphoma
DB00006BivalirudinFor treatment of heparin-induced thrombocytopenia and for the prevention of thrombosis. Bivalirudin is indicated for use in patients undergoing percutaneous coronary intervention (PCI), in patients at moderate to high risk acute coronary syndromes due to unstable angina or non-ST segment elevation in whom a PCI is planned.
DB00007LeuprolideFor treatment of prostate cancer, endometriosis, uterine fibroids and premature puberty
DB00008Peginterferon alfa-2aPeginterferon alfa-2a is indicated for the treatment of HCV in combination with other antiviral drugs in patients over 5 years of age with compensated liver disease [FDA Label]. May be used as a monotherapy in patients with contraindications to or significant intolerance to other anti-viral therapies. Peginterferon alfa-2a is also indicated as a monotherapy for adult patients with HBeAg positive and HBeAg negative chronic hepatitis B infection who have compensated liver disease and evidence of viral replication and liver inflammation [FDA Label].
DB00010SermorelinFor the treatment of dwarfism, prevention of HIV-induced weight loss
DB00011Interferon alfa-n1For treatment of venereal or genital warts caused by the Human Papiloma Virus
DB00012Darbepoetin alfaFor the treatment of anemia (from renal transplants or certain HIV treatment)
DB00014GoserelinGoserelin is indicated for: - Use in combination with flutamide for the management of locally confined carcinoma of the prostate - Palliative treatment of advanced carcinoma of the prostate - The management of endometriosis - Use as an endometrial-thinning agent prior to endometrial ablation for dysfunctional uterine bleeding - Use in the palliative treatment of advanced breast cancer in pre- and perimenopausal women
DB00016ErythropoietinIndicated in adult and paediatric patients for the: - treatment of anemia due to Chronic Kidney Disease (CKD) in patients on dialysis and not on dialysis. - treatment of anemia due to zidovudine in patients with HIV-infection. - treatment of anemia due to the effects of concomitant myelosuppressive chemotherapy, and upon initiation, there is a minimum of two additional months of planned chemotherapy. - reduction of allogeneic RBC transfusions in patients undergoing elective, noncardiac, nonvascular surgery.
DB00017Salmon CalcitoninUsed in the treatment of symptomatic Paget's disease for patients unresponsive to alternate treatments or intolerant to such treatments. In addition, it is used in emergency situations when serum calcium levels must be decreased quickly until the underlying condition is identified. It can also be added to existing therapeutic regimens for hypercalcemia such as intravenous fluids and furosemide, oral phosphate or corticosteroids, or other agents. Calcitonin can be used in patients with azotemia and cases where intravenous fluids would be contraindicated due to limited cardiac reserves. Also for the treatment of post-menopausal osteoporosis in women more than 5 years post-menopause.
DB00018Interferon alfa-n3For the intralesional treatment of refractory or recurring external condylomata acuminata.
DB00019PegfilgrastimPegfilgrastim is indicated for use in patients receiving myelosuppressive chemotherapy for non-myeloid malignancies to reduce the incidence of infection. It is also indicated to increase in patients with acute myelosuppresive radiation exposure.
DB00020SargramostimFor the treatment of cancer and bone marrow transplant
DB00022Peginterferon alfa-2bPeginterferon alfa-2b is indicated for the treatment of HCV in combination with [DB00811] and a NS3/4A protease inhibitor for genotype 1 or without a NS3/4A protease inhibitor for genotypes 2-6 [FDA Label]. May be used as a monotherapy in patients with contraindications to or significant intolerance to other anti-viral therapies.
DB00024Thyrotropin alfaFor detection of residueal or recurrent thyroid cancer
DB00026AnakinraFor the treatment of adult rheumatoid arthritis and treatment of Neonatal-Onset Multisystem Inflammatory Disease (NOMID).
DB00027Gramicidin DFor treatment of skin lesions, surface wounds and eye infections.
DB00030Insulin HumanHuman insulin is indicated to improve glycemic control in adults and pediatric patients with diabetes mellitus.
DB00032MenotropinsFor the treatment of female infertility
DB00033Interferon gamma-1bInterferon gamma-1b is used for the treatment of Chronic granulomatous disease and Osteopetrosis.
DB00034Interferon Alfa-2a, RecombinantFor the treatment of chronic hepatitis C, hairy cell leukemia, AIDS-related Kaposi's sarcoma, and chronic myelogenous leukemia. Also for the treatment of oral warts arising from HIV infection.
DB00035Desmopressin- Indicated for the treatment of nocturia due to nocturnal polyuria in adults who awaken at least 2 times per night to void (intranasal). - Indicated as antidiuretic replacement therapy in the management of central cranial diabetes insipidus and for management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region (intranasal/parenteral). - Indicated for patients with hemophilia A with factor VIII coagulant activity levels greater than 5% or mild to moderate classic von Willebrand's Disease (Type I) with factor VIII levels greater than 5% during surgical procedures and postoperatively to maintain hemostasis (parenteral).
DB00038OprelvekinIndicated for the prevention of severe thrombocytopenia and the reduction of the need for platelet transfusions following myelosuppressive chemotherapy in adult patients with nonmyeloid malignancies who are at high risk of severe thrombocytopenia.[Label]
DB00039PaliferminFor treatment of oral mucositis associated with chemotherapy and radiation therapy.
DB00040GlucagonFor treatment of severe hypoglycemia, also used in gastrointestinal imaging
DB00041AldesleukinFor treatment of adults with metastatic renal cell carcinoma.
DB00046Insulin LisproInsulin lispro is indicated to improve glycemic control in adults and children with diabetes mellitus.
DB00047Insulin glargineInsulin glargine is indicated to improve glycemic control in adults and pediatric patients with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus.
DB00050CetrorelixFor the inhibition of premature LH surges in women undergoing controlled ovarian stimulation
DB00052SomatotropinFor treatment of dwarfism, acromegaly and prevention of HIV-induced weight loss
DB00054AbciximabAbciximab is indicated as an adjunct to percutaneous coronary intervention for the prevention of cardiac ischemic complications in patients undergoing percutaneous coronary intervention and in patients with unstable angina not responding to conventional medical therapy when percutaneous coronary intervention is planned within 24 hours. Abciximab is intended for use with aspirin and heparin and has been studied only in that setting.
DB00057Indium In-111 satumomab pendetideFor diagnosis of extrahepatic malignant cancers
DB00058Alpha-1-proteinase inhibitorFor chronic augmentation and maintenance therapy in individuals with alpha1-proteinase inhibitor (A1-PI) deficiency and clinical evidence of emphysema.
DB00060Interferon beta-1aFor treatment of relapsing/remitting multiple sclerosis, also for condyloma acuminatum
DB00066FollitropinIn women having been diagnosed with primary ovarian failure, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility. In men with hypogonadotrophic hypogonadism, it is used to induce spermatogenesis. Follitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (GIFT) or in vitro fertilization (IVF).
DB00067VasopressinFor the treatment of enuresis, polyuria, diabetes insipidus, polydipsia and oesophageal varices with bleeding
DB00068Interferon beta-1bInterferon beta-1b is a drug used for the treatment of relapsing/remitting multiple sclerosis. It has been shown to slow the advance of the disease as well as to decrease the frequency of attacks.
DB00069Interferon alfacon-1For the treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma
DB00071Insulin PorkFor the treatment of type I and II diabetes mellitus.
DB00080DaptomycinFor the treatment of complicated skin and skin structure infections caused by susceptible strains of Gram-positive microorganisms.
DB00082PegvisomantPegvisomant is a growth hormone receptor antagonist used for the treatment of acromegaly.
DB00093FelypressinFor use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential.
DB00094UrofollitropinFor treatment of female infertility
DB00102BecaplerminFor topical treatment of skin ulcers (from diabetes)
DB00104OctreotideFor treatment of acromegaly and reduction of side effects from cancer chemotherapy
DB00105Interferon alfa-2bFor the treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma.
DB00106AbarelixFor palliative treatment of advanced prostate cancer.
DB00107OxytocinUsed for labor induction, augmentation of labor, postpartum abbreviation of third stage of labor, postpartum control of uterine bleeding, termination of pregnancy and for the evaluation of fetal respiratory capability. Oxytocin cannot be used for elective induction of labor, there must be a clear medical requirement.
DB00109EnfuvirtideEnfuvirtide is an antiretroviral drug used in combination therapy for the treatment of HIV-1/AIDS.
DB00143GlutathioneFor nutritional supplementation, also for treating dietary shortage or imbalance
DB00168AspartameUsed as a diet supplement and sugar substitute.
DB00183PentagastrinUsed as a diagnostic aid for evaluation of gastric acid secretory function
DB00290BleomycinFor palliative treatment in the management malignant neoplasm (trachea, bronchus, lung), squamous cell carcinoma, and lymphomas.
DB00314CapreomycinUsed in the treatment of tuberculosis in combination with other drugs.
DB00362AnidulafunginFor use in the treatment of the following fungal infections: Candidemia and other forms of Candida infections (intra-abdominal abscess, and peritonitis), Aspergillus infections, and esophageal candidiasis. Also considered an alternative treatment for oropharyngeal canaidiasis.
DB00403CeruletideCaerulein is used in the treatment of paralytic ileus and as diagnostic aid in pancreatic malfunction.
DB00512VancomycinA variety of dosage forms (for example, oral, injections, etc.) exist for the treatment of serious or severe infections caused by susceptible strains of methicillin-resistant (beta-lactam-resistant) staphylococci [FDA Label]. Additionally, a unique FDA approved oral liquid treatment is also available and indicated for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by _Staphylococcus aureus_, including methicillin-resistant strains [L1196].
DB00520CaspofunginFor the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies.
DB00584EnalaprilFor the treatment of essential or renovascular hypertension and symptomatic congestive heart failure. It may be used alone or in combination with thiazide diuretics.
DB00626BacitracinFor the treatment of infants with pneumonia and empyema caused by staphylococci shown to be susceptible to the drug. Also used in ointment form for topical treatment of a variety of localized skin and eye infections, as well as for the prevention of wound infections. Used against gram positive bacteria. Bacitracin is also used as an inhibitor of proteases and other enzymes. However, specific activity of bactracin's inhibition of protein disulfide isomerase has been called into question.
DB00644GonadorelinFor evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation.
DB00666NafarelinFor treatment of central precocious puberty (true precocious puberty, GnRH-dependent precocious precocity, complete isosexual precocity) in children of both sexes and for the treatment of endometriosis.
DB00722LisinoprilFor the treatment of hypertension and symptomatic congestive heart failure. May be used in conjunction with thrombolytic agents, aspirin and/or β-blockers to improve survival in hemodynamically stable individuals following myocardial infarction. May be used to slow the progression of renal disease in hypertensive patients with diabetes mellitus and microalbuminuria or overt nephropathy.
DB00803ColistinFor the treatment of acute or chronic infections due to sensitive strains of certain gram-negative bacilli, particularly Pseudomonas aeruginosa.
DB00855Aminolevulinic acidAminolevulinic acid plus blue light illumination using a blue light photodynamic therapy illuminator is indicated for the treatment of minimally to moderately thick actinic keratoses of the face or scalp.
DB00970DactinomycinFor the treatment of Wilms' tumor, childhood rhabdomyosarcoma, Ewing's sarcoma and metastatic, nonseminomatous testicular cancer as part of a combination chemotherapy and/or multi-modality treatment regimen
DB01072AtazanavirUsed in combination with other antiretroviral agents for the treatment of HIV-1 infection, as well as postexposure prophylaxis of HIV infection in individuals who have had occupational or nonoccupational exposure to potentially infectious body fluids of a person known to be infected with HIV when that exposure represents a substantial risk for HIV transmission.
DB01111ColistimethateFor the treatment of acute or chronic infections due to sensitive strains of certain gram-negative bacilli, particularly _Pseudomonas aeruginosa_.
DB01141MicafunginFor use in the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, as well as esophageal candidiasis, and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation. Micafungin is also used as an alternative for the treatment of oropharyngeal candidiases and has been used with some success as primary or salvage therapy, alone or in combination with other antifungals, for the treatment of invasive aspergillosis.
DB01277MecaserminFor the long-term treatment of growth failure in pediatric patients with Primary IGFD or with GH gene deletion who have developed neutralizing antibodies to GH [A2322]. It is not indicated to treat Secondary IGFD resulting from GH deficiency, malnutrition, hypothyroidism or other causes; it is not a substitute for GH therapy.
DB01278PramlintideFor the treatment of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy.
DB01282CarbetocinUsed to control postpartum hemorrhage and bleeding after giving birth.
DB01284TetracosactideFor use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.
DB01285CorticotropinFor use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.
DB01306Insulin AspartInsulin aspart is indicated to improve glycemic control in adults and children with diabetes mellitus.
DB01307Insulin DetemirInsulin detemir is indicated to improve glycemic control in adults and children with diabetes mellitus.
DB01309Insulin GlulisineInsulin glulisine is indicated to improve glycemic control in adults and pediatric patients with diabetes mellitus.
DB01348SpiraprilSpirapril is an ACE inhibitor class drug used to treat hypertension.
DB01369QuinupristinFor the treatment of bacterial infections (usually in combination with dalfopristin).
DB01669Virginiamycin M1For the treatment of bacterial infections.
DB01683ChymostatinNot Available
DB01764DalfopristinFor the treatment of bacterial infections (usually in combination with quinupristin).
DB02083N,N-dimethylglycineNot Available
DB02123Glycochenodeoxycholic AcidNot Available
DB02255GM6001Not Available
DB02307N-(1-Carboxy-3-Phenylpropyl)Phenylalanyl-Alpha-AsparagineNot Available
DB02341Mdl 101,146Not Available
DB02557PhosphoramidonNot Available
DB02578Glycyl-L-Alpha-Amino-Epsilon-Pimelyl-D-Alanyl-D-AlanineNot Available
DB02638TerlipressinCommonly used to stop bleeding of varices in the food pipe (oesophagus).
DB02855N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-ProlineNot Available
DB02975GE-2270ANot Available
DB03032S-OctylglutathioneNot Available
DB03295GlutathionylspermidineNot Available
DB03395EnalkirenNot Available
DB03408gamma-GlutamylcysteineNot Available
DB03436GallichromeNot Available
DB03470TrypanothioneNot Available
DB03535Z-Pro-ProlinalNot Available
DB03632ArgifinNot Available
DB03889S-(N-Hydroxy-N-Bromophenylcarbamoyl)GlutathioneNot Available
DB04111BalhimycinNot Available
DB04132S-HexylglutathioneNot Available
DB04191Skf 107457Not Available
DB04269Cyclotheonamide ANot Available
DB04350ArgadinNot Available
DB04391Aeruginosin 98-BNot Available
DB04738MotuporinNot Available
DB04805Virginiamycin S1Not Available
DB04869OlcegepantFor the treatment of migraine headaches.
DB04894VapreotideFor the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.
DB04899NesiritideFor the intravenous treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity.
DB04900ThymalfasinIndicated as an adjuvant for influenza vaccine in elderly patients and as an adjuvant for both influenza and hepatitis B vaccines in chronic hemodialysis patients who failed to achieve adequate antibody titers from previous immunization.
DB04911OritavancinInvestigated for use/treatment in bacterial infection and skin infections/disorders.
DB04914G17DTIntended for the treatment of various forms of cancer.
DB04921DirucotideFor the treatment of multiple sclerosis (MS).
DB04931AfamelanotideInvestigated for use/treatment in actinic keratosis, keratoses, skin cell studies, and skin infections/disorders.
DB04949PexelizumabFor the treatment of inflammation during cardiac surgery.
DB04952RamoplaninFor the treatment of bacterial infections.
DB04972CanfosfamideIntended for the treatment of various forms of cancer.
DB04977PlitidepsinIntended for the treatment of various forms of cancer.
DB04985TigapotideFor the treatment of late stage Hormone Refractory Prostate Cancer (HRPC) for which no effective therapy currently exists.
DB05029LancovutideInvestigated for use/treatment in cystic fibrosis and eye disorders/infections.
DB05034UlaritideInvestigated for use/treatment in congestive heart failure.
DB05084AbaloparatideInvestigated for use/treatment in postmenopausal osteoporosis to reduce vertebral and/or non-vertebral fractures.
DB05098LeptinInvestigated for use/treatment in lipodystrophy and obesity.
DB05115NN344Investigated for use/treatment in diabetes mellitus type 1 and 2.
DB05128AminocandinInvestigated for use/treatment in fungal infections.
DB05155CR665Investigated for use/treatment in pain (acute or chronic).
DB05158PM02734Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
DB05161ElafinInvestigated for use/treatment in inflammatory disorders (unspecified).
DB05210SF1126For the treatment of various forms of cancer.
DB05258Interferon alfaInvestigated for use/treatment in hepatitis (viral, C), leukemia (lymphoid), leukemia (myeloid), leukemia (unspecified), and melanoma.
DB05259GlatiramerFor reduction of the frequency of relapses in patients with Relapsing-Remitting Multiple Sclerosis.
DB05305Cintredekin BesudotoxInvestigated for use/treatment in brain cancer.
DB05332RomiplostimTreatment of chronic immune thrombocytopenic purpura.
DB05344Ciliary neurotrophic factorInvestigated for use/treatment in eye disorders/infections, macular degeneration, and retinal disorders (unspecified).
DB05393NOV-002Investigated for use/treatment in breast cancer, lung cancer, and ovarian cancer.
DB05394CorticorelinInvestigated for use/treatment in brain cancer and neurologic disorders.
DB05396Albinterferon Alfa-2BInvestigated for use/treatment in hepatitis (viral, C).
DB05413TifuvirtideInvestigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.
DB05434ABT-510Investigated for use/treatment in lymphoma (unspecified), melanoma, and solid tumors.
DB05460EzatiostatInvestigated for use/treatment in myelodysplastic syndrome.
DB05475GolotimodInvestigated for use/treatment in hepatitis (viral, C), infectious and parasitic disease (unspecified), and tuberculosis.
DB05507VX-765Investigated for use/treatment in inflammatory disorders (unspecified) and psoriasis and psoriatic disorders.
DB05521TelaprevirTelaprevir, when used in combination with [DB00811], [DB00008], and [DB00022] is indicated for use in the treatment of chronic HCV genotype 1 infection in adults [FDA Label].
DB05599Fibroblast growth factor-1Investigated for use/treatment in coronary artery disease and peripheral vascular disease.
DB05633GlypromateInvestigated for use/treatment in neurologic disorders.
DB05645LarazotideInvestigated for use/treatment in autoimmune diseases, diabetes mellitus type 1, and gastrointestinal diseases and disorders (miscellaneous).
DB05714FlovagatranInvestigated for use/treatment in thrombosis.
DB05718Maxy-G34Investigated for use/treatment in adverse effects (chemotherapy) and neutropenics.
DB05735CefilavancinInvestigated for use/treatment in bacterial infection, skin infections/disorders, and staph bacterial infections.
DB05739CYT006-AngQbInvestigated for use/treatment in hypertension.
DB05779OglufanideInvestigated for use/treatment in hepatitis (viral, C).
DB05793PRO-542Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections, HIV infection, and pediatric indications.
DB05819NBI-6024Investigated for use/treatment in diabetes mellitus type 1 and pediatric indications.
DB05829Parathyroid hormoneFor use/treatment in osteoporosis.
DB05931PegdinetanibInvestigated for use/treatment in cancer/tumors (unspecified) and macular degeneration.
DB05934CTCE-0214Investigated for use/treatment in adverse effects (chemotherapy), blood (blood forming organ disorders, unspecified), cancer/tumors (unspecified), neutropenics, and vascular diseases.
DB06081CaplacizumabCapacizumab is approved for the treatment of adults experiencing an episode of acquired thrombotic thrombocytopenic purpura (aTTP) in conjunction with plasma exchange and immunosuppression in patients 18 years or older.[A174634, L5302] aTTP is a rare autoimmune condition presented by a disruption of blood clotting order which is translated into systemic microvascular thrombosis leading to profound thrombocytopenia, hemolytic anemia and organ ischemia. It is caused by the production of autoantibodies against ADAMTS-13 which is the protein in charge of cleaving the von-Wilebrand factor. The lack of this process produces the generation of ultra large von Wilebrand multimers that bind to platelets and form microthrombi and causing thromboembolic complications.[A174649] Previously, capacizumab was under review for the prevention of thrombosis in high-risk patients with acute coronary syndrome undergoing percutaneous coronary intervention but this indication was withdrawn.[A174634]
DB06138IRL-1620Investigated for use/treatment in cancer/tumors (unspecified).
DB06149TeicoplaninFor the treatment of bacterial infections caused by susceptible microorganisms.
DB06176RomidepsinFor the treatment of cutaneous T-cell lymphoma (CTCL) or/and peripheral T-cell lymphoma (PTCL) in patients who have received at least one prior systemic therapy. These indications are based on response rate. Clinical benefit such as improvement in overall survival has not been demonstrated.
DB06179DarinaparsinInvestigated for use/treatment in blood (blood forming organ disorders, unspecified), cancer/tumors (unspecified), solid tumors, multiple myeloma, and liver cancer.
DB06182TalabostatInvestigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), lung cancer, melanoma, and pancreatic cancer.
DB06196IcatibantApproved for use in acute attacks of hereditary angioedema (HAE). Investigated for use/treatment in angioedema, liver disease, and burns and burn infections.
DB06219DalbavancinDalbavancin for injection is indicated for the treatment of adult patients with acute bacterial skin and skin structure infections (ABSSSI), caused by susceptible isolates of the following gram-positive microorganisms: Staphylococcus aureus (including methicillin-susceptible and methicillin-resistant strains), Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus anginosus group (including Streptococcus anginosus, Streptococcus intermedius, Streptococcus constellatus) and Enterococcus faecalis (vancomycin susceptible strains) [FDA Label, F2356]. Dalbavancin is not active against gram-negative bacteria; therefore, combination therapy may be clinically indicated if the ABSSSI is polymicrobial and includes a suspected or documented gram-negative pathogen [F2356]. To reduce the development of drug-resistant bacteria and maintain the effectiveness of dalbavancin and other antibacterial drugs, dalbavancin should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria [FDA Label, F2356]. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy [FDA Label, F2356]. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy [FDA Label, F2356].
DB06244TraferminInvestigated for use/treatment in coronary artery disease, peripheral vascular disease, periodontal disease, bone fractures, entero-related fistulae, and diabetic foot ulcers.
DB06260AviptadilNot Available
DB06285TeriparatideFor the treatment of osteoporosis in men and postmenopausal women who are at high risk for having a fracture. Also used to increase bone mass in men with primary or hypogonadal osteoporosis who are at high risk for fracture.
DB06335SaxagliptinTreatment of type 2 diabetes mellitus to improve glycemic control in combination with other agents or as monotherapy.
DB06379Calcitonin gene-related peptideInvestigated for use/treatment in myocardial infarction, heart disease, and asthma.
DB06404Human C1-esterase inhibitorFor routine prophylaxis against angioedema attacks in adolescent and adult patients with Hereditary Angioedema (HAE).
DB06423EndostatinInvestigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy.
DB06434RepiferminInvestigated for use/treatment in bone marrow transplant, ulcers, and inflammatory bowel disease.
DB06493VelaferminInvestigated for use/treatment in adverse effects (chemotherapy).
DB06534ThrombopoietinInvestigated for use/treatment in thrombocytopenia.
DB06549LabradimilInvestigated for use/treatment in brain cancer and pediatric indications.
DB06562EmfilerminInvestigated for use/treatment in adverse effects (chemotherapy), reproductive health, and infertility.
DB06645AnamorelinInvestigated for use/treatment in cachexia and anorexia.
DB06655LiraglutideLiraglutide is indicated in combination with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus[Label]. It is also indicated to reduce the risk of major adverse cardiovascular events in patients with type 2 diabetes mellitus as well as cardiovascular disease[Label].
DB06663PasireotideFor the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery has not been curative or is not an option.
DB06699DegarelixDegaralix is used for the management of advanced prostate cancer.
DB06719BuserelinBuserelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction.
DB06763SaralasinNot Available
DB06785GanirelixFor the inhibition of premature LH surges in women undergoing controlled ovarian hyperstimulation.
DB06788HistrelinAs the product Supprelin LA (FDA), histrelin is indicated for the treatment of children with central precocious puberty (CPP). As the product Vantas (FDA), histrelin is indicated for the palliative treatment of advanced prostate cancer.
DB06791LanreotideLanreotide is a somatostatin analog approved for treatment of neuroendocrine tumours and acromegaly. (2)
DB06823TioproninTiopronin is indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria consisting of a urinary cystine concentration greater than 500 mg/day, and who have failed treatment with non-pharmacological measures of increased fluid intake, decreased sodium and protein intake, and urine alkalinization.
DB06825TriptorelinTriptorelin is indicated for the palliative treatment of advanced prostate cancer.
DB06827ViomycinViomycin is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis.
DB08626ThiorphanNot Available
DB08856DADLENot Available
DB08861DPDPENot Available
DB08862CholecystokininFor use as a diagnostic aid for evaluation of gallbladder disorders. It is also used in conjunction with secretin in pancreatic insufficiency [L1634].
DB08869TesamorelinTesamorelin acetate is a synthetic analogue of human hypothalamic Growth Hormone Releasing Factor (hGRF) indicated to induce and maintain a reduction of excess abdominal fat in HIV-infected patients with lipodystrophy.
DB08888OcriplasminOcriplasmin is a proteolytic enzyme indicated for the treatment for symptomatic vitreomacular adhesion.
DB08889CarfilzomibCarfilzomib is indicated for the treatment of patients with multiple myeloma who have received at least two prior therapies including bortezomib and an immunomodulatory agent and have demonstrated disease progression on or within 60 days of completion of the last therapy. Approval is based on response rate.
DB08900TeduglutideTreatment of short bowel syndrome (SBS), malabsorption associated with the removal of the intestine, in adults patients who are dependent on parenteral support.
DB08904Certolizumab pegolCertolizumab pegol has been approved for several different conditions listed below: - Symptomatic management of Chron's disease patients and for the maintenance of clinical response in patients with moderate to severe disease with inadequate response to conventional therapy. - Treatment of adult patients with moderate to severely active rheumatoid arthritis. - Treatment of adult patients with active psoriatic arthritis. - Treatment of adult patients with active ankylosing spondylitis. - Treatment of adult patients with moderate-to-severe plaque psoriasis that are candidates for systemic therapy or phototherapy.[FDA label] - Treatment of adult patients with active non-radiographic axial spondyloarthritis with objective signs of inflammation.[L5819] In Canada, certolizumab pegol is additionally approved in combination with [methotrexate] for the symptomatic treatment, including major clinical response, and for the reduction of joint damage in adult patients with moderately to severely active rheumatoid arthritis and psoriatic arthritis.[L5825] Inflammation is a biological response against a potential threat. This response can be normal but in certain conditions, the immune system can attack the body's normal cells or tissues which causes an abnormal inflammation.[L5840] TNF-alpha has been identified as a key regulator of the inflammatory response. The signaling cascades of this inflammatory mediator can produce a wide range of reactions including cell death, survival, differentiation, proliferation and migration.[A176660]
DB08993EnviomycinNot Available
DB09043AlbiglutideIndicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
DB09045DulaglutideIndicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
DB09046MetreleptinMetreleptin is indicated as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy.
DB09059AtosibanAtosiban is indicated for use in delaying imminent pre-term birth in pregnant adult women with: - regular uterine contractions of at least 30 s duration at a rate of at least 4 per 30 min - a cervical dilation of 1-3cm (0-3cm for nulliparas) and effacement of at least 50% - a gestational age of 24-33 weeks - a normal fetal heart rate
DB09066Corifollitropin alfaControlled ovarian stimulation [L2273] in cases of women who are undergoing fertility treatment to stimulate the development of more than one mature egg simultaneously in the ovaries in combination with a gonadotrophin-releasing hormone (GnRH) antagonist (a type of medicine also used in fertility treatments)[L2270].
DB09067Corticorelin ovine triflutateCorticorelin is indicated for use in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome.
DB09098SomatremSomatrem is a recombinant human growth hormone indicated for: (a) treatment of paediatric patients with growth failure due to growth hormone deficiency (GHD), (b) treatment of paediatric patients with growth failure due to idiopathic short stature (ISS), (c) treatment of paediatric patients with growth failure due to Turner syndrome (TS), (d) treatment of paediatric patients with growth failure due to chronic kidney disease (CKD) up to the time of renal transplantation, (e) treatment of adults with childhood-onset GHD, or (f) treatment of adults with adult-onset GHD [FDA Label].
DB09099SomatostatinFor the symptomatic treatment of acute bleeding from esophageal varices. Other treatment options for long-term management of the condition may be considered if necessary, once initial control has been established.
DB09103AncestimAncestim, in combination with filgrastim, is indicated for the setting of autologous peripheral blood progenitor cell transplantation in patients at risk of poor peripheral blood progenitor cell mobilisation.[L1090] The use of ancestim with filgrastim will generate a sustained increase in the number of peripheral blood progenitor cells capable of engraftment. It is used for mobilization of progenitor cells from the bone marrow to the peripheral blood with or withouth mobilizing chemotherapy. The harvested progenitor cells can be used for transplant following myelosuppressive or myeloablative therapies.[L1089]
DB09107Methoxy polyethylene glycol-epoetin betaFor the treatment of patients with anaemia associated with chronic kidney disease. Not a substitute for RBC transfusion if immediate correction of anemia is required.
DB09122Peginterferon beta-1aFor the treatment of patients with relapsing forms of multiple sclerosis.
DB09126Chorionic Gonadotropin (Human)For the treatment of prepubertal cryptorchidism (not due to anatomical obstruction), for the treatment of selected cases of hypogonadotropic hypogonadism (hypogonadism secondary to a pituitary deficiency) in males and for the induction of ovulation and pregnancy in the anovulatory, infertile woman in whom the cause of anovulation is secondary and not due to primary ovarian failure, and who has been appropriately pretreated with human menotropins.
DB09142SincalideAs the product Kinevac (FDA), sincalide is used for the following indications: 1) to stimulate gallbladder contraction, as may be assessed by various methods of diagnostic imaging, or to obtain by duodenal aspiration a sample of concentrated bile for analysis of cholesterol, bile salts, phospholipids, and crystals; (2) to stimulate pancreatic secretion (especially in conjunction with secretin) prior to obtaining a duodenal aspirate for analysis of enzyme activity, composition, and cytology; (3) to accelerate the transit of a barium meal through the small bowel, thereby decreasing the time and extent of radiation associated with fluoroscopy and x-ray examination of the intestinal tract.
DB09221PolaprezincPeptic ulcer disease, dyspepsia [L1308].
DB09421ProtirelinNot Available
DB09477EnalaprilatEnalaprilat injection is indicated for the treatment of hypertension when oral therapy is not practical.
DB09527Secretin porcineNot Available
DB09564Insulin DegludecInsulin degludec is indicated to improve glycemic control in patients 1 year of age and older with diabetes mellitus.
DB11095DesirudinIndicated as prophylaxis of deep vein thrombosis for patients undergoing hip replacement surgery.
DB11296PrezatideCommonly used in cosmetic products for the skin and hair [A19503].
DB11403EmodepsideNot Available
DB11467ThiostreptonNot Available
DB11476VirginiamycinNot Available
DB11510DeslorelinNot Available
DB11567Insulin peglisproNot Available
DB11598Antithrombin III humanAntithrombin III human is a human antithrombin (AT) indicated in patients with hereditary antithrombin deficiency for the treatment and prevention of thromboembolism and prevention of peri-operative and peri-partum thromboembolism
DB11624Epoetin deltaNot Available
DB11628DepreotideNot Available
DB11631Eptotermin AlfaNot Available
DB11639Dibotermin alfa- indicated for the treatment of acute tibia fractures in adults, as an adjunct to standard care using open fracture reduction and intramedullary unreamed nail fixation [FDA Label]. - indicated for single-level lumbar interbody spine fusion as a substitute for autogenous bone graft in adults with degenerative disc disease who have had at least 6 months of non-operative treatment for this condition [L1391].
DB11653BremelanotideNot Available
DB11668Rusalatide acetateNot Available
DB11695CarnosineNot Available
DB11696RacecadotrilNot Available
DB11700SetmelanotideNot Available
DB11709Acetyl hexapeptide-8Not Available
DB11724BombesinNot Available
DB11777CenderitideNot Available
DB11782BirinapantNot Available
DB11788Neuropeptide YNot Available
DB11808FaldaprevirNot Available
DB11826LampalizumabNot Available
DB11842Angiotensin IIAngiotensin II is a vasoconstrictor indicated for increasing blood pressure in adults with septic or other distributive shock [FDA Label].
DB11854AstodrimerNot Available
DB11869ValspodarNot Available
DB11876Alanyl GlutamineNot Available
DB11882BPC-157Not Available
DB11895LenomorelinNot Available
DB11906AcylineNot Available
DB11928VosoritideNot Available
DB11955AvoterminNot Available
DB11975TAK-448Not Available
DB11981ElamipretideNot Available
DB11991OprozomibNot Available
DB11997Interleukin-7Not Available
DB12003Thymosin beta-4Not Available
DB12042IbodutantNot Available
DB12054BQ-123Not Available
DB12075NagrestipenNot Available
DB12076SurotomycinNot Available
DB12088TT-232Not Available
DB12126BradykininNot Available
DB12139AlisporivirNot Available
DB12182BinetrakinNot Available
DB12279OBP-801Not Available
DB12292BarusibanNot Available
DB12349DulanerminNot Available
DB12370IpamorelinNot Available
DB12431MuplestimNot Available
DB12451SCY-635Not Available
DB12486ElobixibatNot Available
DB12490ForigerimodNot Available
DB12495SelepressinNot Available
DB12519SarcosineNot Available
DB12525MolgramostimNot Available
DB12538NepadutantNot Available
DB12602PentetreotideNot Available
DB12613DavunetideNot Available
DB12616SpriferminNot Available
DB12620Nerve Growth FactorNot Available
DB12648Nona-arginineNot Available
DB12652Endothelin-1Not Available
DB12677SoblidotinNot Available
DB12678RelamorelinNot Available
DB12699BalugrastimNot Available
DB12711LTX-109Not Available
DB12730Dolastatin 10Not Available
DB12738TiplimotideNot Available
DB12748LTX-315Not Available
DB12755Zoptarelin doxorubicinNot Available
DB12777SomatoprimNot Available
DB12795CMX-2043Not Available
DB12822Pancreatic PolypeptideNot Available
DB12876GS-9256Not Available
DB12880Interleukin-10Not Available
DB12992Bleomycin A6Not Available
DB13006CibinetideNot Available
DB13033Urocortin-2Not Available
DB13067RotigaptideNot Available
DB130689-(N-methyl-L-isoleucine)-cyclosporin ANot Available
DB13074MacimorelinIndicated for the diagnosis of adult growth hormone deficiency (AGHD) [FDA Label].
DB13144LenograstimThe drug is used to reduce the risk of life-threatening infection in patients with neutropenia, particularly after cytotoxic chemotherapy. Lenograstim is indicated as a treatment to reduce the duration of neutropenia and the severity of infections in patients with non-myeloid malignancy who have undergone autologous or allogeneic bone marrow transplantation, or treatment with established cytotoxic chemotherapy and in addition to reduce the incidence of infection associated with established cytotoxic chemotherapy. Lenograstim is also indicated to mobilise peripheral blood progenitor cells (PBPCs) with Lenograstim alone, or after myelosuppressive chemotherapy, in order to accelerate haematopoietic recovery by infusion of such cells, after myelosuppressive or myeloablative therapy. Lenograstim is also indicated to accelerate the engraftment of these cells after their reinfusion. GRANOCYTE is also indicated for the treatment of severe chronic neutropenia including congenital agranulocytosis (Kostmann's syndrome).
DB13200LipegfilgrastimIndicated for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in adult patients treated with cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid leukaemia and myelodysplastic syndromes) [L2441].
DB13207Arginine glutamateNot Available
DB13298AlsactideNot Available
DB13299SulglicotideNot Available
DB13464OrnipressinNot Available
DB13503TyrothricinTyrothricin is used as an over the counter topical antibiotic.
DB13517AngiotensinamideNot Available
DB13590Calcium pangamateNot Available
DB13615MifamurtideIndicated in children, adolescents and young adults for the treatment of high-grade, resectable, non-metastatic osteosarcoma after macroscopically complete surgical resection, typically in combination with post-operative multi-agent chemotherapy [L1203].
DB13704PristinamycinNot Available
DB13742ElcatoninNot Available
DB13798DemoxytocinNot Available
DB13809Paclitaxel poliglumexNot Available
DB13928SemaglutideSemaglutide is indicated to improve glycemic control in adults with type 2 diabetes mellitus as an adjunct of diet and exercise. The approved therapeutic doses are 0.5 mg and 1 mg.[L1068] Diabetes mellitus type 2 is a long-term metabolic disorder characterized by high blood sugar, insulin resistance and lack of insulin. Its onset is determined by the loss ability of beta cells to respond to an increased plasma glucose. This disease is predominantly caused by lifestyle factors like overweight and obesity. The key feature on type 2 diabetes is the presence of insulin resistance which reduced the capacity of insulin to exert its functions at normal at any given concentration. The secretion of insulin is stimulated by the action of incretins in the gut like glucagon-like peptide 1, which also delays gastric emptying and induces satiety, and glucose-dependent insulinotropic polypeptide.[T59]
DB13985Lutetium Lu 177 dotatateIndicated for the treatment of somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors (GEP-NETs), including foregut, midgut, and hindgut neuroendocrine tumors in adults [FDA Label].
DB14027TaspoglutideNot Available
DB05624TeverelixInvestigated for use/treatment in benign prostatic hyperplasia, endometriosis, and prostate cancer.
DB14057ValinomycinNot Available
DB14058BasifunginNot Available
DB14072Reversin 121Not Available
DB14076Interleukin-1 alpha, human recombinantNot Available
DB14131Basic Fibroblast Growth FactorBasic Fibroblast Growth Factor is not currently approved for any FDA or Health Canada approved indications.
DB14145NepiderminNot Available
DB14472Insulin-like growth factor IINot Available
DB00099FilgrastimThis drug is a leucocyte growth factor [FDA label] indicated to: Decrease the incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a significant incidence of severe neutropenia with fever [FDA label]. Reduce the time to neutrophil recovery and the duration of fever, following induction or consolidation chemotherapy treatment in patients with acute myeloid leukemia (AML) [FDA label] Reduce the duration of neutropenia and neutropenia-related clinical sequelae‚ e.g.‚ febrile neutropenia, in patients with nonmyeloid malignancies undergoing myeloablative chemotherapy followed by bone marrow transplantation (BMT) [FDA label] Mobilize autologous hematopoietic progenitor cells into the peripheral blood for collection by leukapheresis [FDA label] Reduce the incidence and duration of sequelae of severe neutropenia (e.g.‚ fever‚ infections‚ oropharyngeal ulcers) in symptomatic patients with congenital neutropenia‚ cyclic neutropenia‚ or idiopathic neutropenia [FDA label]. Neupogen is approved for treatment of patients with radiation-induced myelosuppression following a radiological/nuclear incident [L3739].
DB09532Secretin humanIndicated for the stimulation of: - pancreatic secretions, including bicarbonate, to aid in the diagnosis of pancreatic exocrine dysfunction [FDA Label]. - gastrin secretion to aid in the diagnosis of gastrinoma [FDA Label]. - pancreatic secretions to facilitate the identification of the ampulla of Vater and accessory papilla during endoscopic retrograde cholangiopancreatography (ERCP) [FDA Label].
DB14642LypressinNot Available
DB07558acetylleucyl-leucyl-norleucinalNot Available
DB02458S-(2,4-dinitrophenyl)glutathioneNot Available
DB02691Glycocholic acidNot Available
DB03310Glutathione disulfideNot Available
DB11693VoclosporinNot Available
DB11835Indium In-111 pentetreotideNot Available
DB12581OzarelixNot Available
DB13170PlecanatidePlecanatide stimulates intestinal fluid secretions in the gastrointestinal tract to support regular bowel function. Plecanatide, taken orally once daily, works locally in the upper GI tract to stimulate secretion of intestinal fluid and support regular bowel function.
DB05004Peptide YY (3-36)Investigated for use/treatment in metabolic disease and obesity.
DB00091CiclosporinCyclosporine is officially approved for different conditions listed below: * Prophylaxis of organ rejection in kidney, liver, and heart allogeneic transplants. For this indication, it can be used concomitantly with azathioprine and corticosteroids. * Treatment of patients with severe active, rheumatoid arthritis when the patient no longer responds to methotrexate. * Concomitantly with methotrexate for the treatment of patients with severe active rheumatoid arthritis when patients do not respond to methotrexate treatment alone. * Treatment of adult nonimmunocompromised patients with severe, recalcitrant, plaque psoriasis that have failed to respond to at least one systemic therapy or when systemic therapies are not tolerated or contraindicated.[FDA label] * Its ophthalmic solution is indicated to increase tear production in patients with keratoconjunctivitis sicca in patients from 4 years old.[L5158] * Prevention of graft rejection following bone marrow transplantation and in the treatment of graft-versus-host disease (GVHD). * Treatment of steroid dependent and steroid-resistant nephrotic syndrome due to glomerular diseases such as minimal change nephropathy, focal and segmental glomerulosclerosis or membranous glomerulonephritis in adults and children.[F3091] Away from all this approved and reviewed indications, cyclosporine is commonly used on dermatology for the treatment of various inflammatory skin conditions such as atopic dermatitis, blistering disorders, and connective tissue diseases.[A174085]
DB06651DiaPep 277Investigated for use/treatment in diabetes mellitus type 1, autoimmune diseases, and diabetes mellitus type 2.
DB14741Luteinizing hormoneNot Available
DB00781Polymyxin BPolymyxin B is indicated for the treatment of infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of Pseudomonas aeruginosa[FDA Label].
DB14760NarlaprevirNot Available
DB05386RegramostimInvestigated for use/treatment in adverse effects (chemotherapy) and bone marrow transplant.
DB05875Sar9, Met (O2)11-Substance PInvestigated for use/treatment in acute respiratory distress syndrome (ARDS) and viral infection.
DrugDrug NameTargetType
DB00004Denileukin diftitoxInterleukin-2 receptor subunit alphatarget
DB00004Denileukin diftitoxCytokine receptor common subunit gammatarget
DB00004Denileukin diftitoxInterleukin-2 receptor subunit betatarget
DB00007LeuprolideGonadotropin-releasing hormone receptortarget
DB00007LeuprolideCytochrome P450 3A4enzyme
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 2target
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 1target
DB00008Peginterferon alfa-2aCytochrome P450 1A2enzyme
DB00010SermorelinGrowth hormone-releasing hormone receptortarget
DB00011Interferon alfa-n1Interferon alpha/beta receptor 2target
DB00011Interferon alfa-n1Interferon alpha/beta receptor 1target
DB00012Darbepoetin alfaErythropoietin receptortarget
DB00014GoserelinLutropin-choriogonadotropic hormone receptortarget
DB00014GoserelinGonadotropin-releasing hormone receptortarget
DB00016ErythropoietinErythropoietin receptortarget
DB00017Salmon CalcitoninCalcitonin receptortarget
DB00018Interferon alfa-n3Interferon alpha/beta receptor 1target
DB00018Interferon alfa-n3Interferon alpha/beta receptor 2target
DB00019PegfilgrastimGranulocyte colony-stimulating factor receptortarget
DB00019PegfilgrastimNeutrophil elastasetarget
DB00020SargramostimGranulocyte-macrophage colony-stimulating factor receptor subunit alphatarget
DB00020SargramostimBone marrow proteoglycantarget
DB00020SargramostimInterleukin-3 receptor subunit alphatarget
DB00020SargramostimCytokine receptor common subunit betatarget
DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 1target
DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 2target
DB00022Peginterferon alfa-2bCytochrome P450 1A2enzyme
DB00022Peginterferon alfa-2bCytochrome P450 2D6enzyme
DB00022Peginterferon alfa-2bCytochrome P450 2C9enzyme
DB00024Thyrotropin alfaThyrotropin receptortarget
DB00026AnakinraInterleukin-1 receptor type 1target
DB00027Gramicidin DMultidrug resistance protein 1transporter
DB00030Insulin HumanInsulin receptortarget
DB00030Insulin HumanRetinoblastoma-associated proteintarget
DB00030Insulin HumanInsulin-like growth factor 1 receptortarget
DB00030Insulin HumanInsulin-degrading enzymeenzyme
DB00030Insulin HumanNeuroendocrine convertase 2enzyme
DB00030Insulin HumanCarboxypeptidase Eenzyme
DB00030Insulin HumanNeuroendocrine convertase 1enzyme
DB00032MenotropinsFollicle-stimulating hormone receptortarget
DB00032MenotropinsLutropin-choriogonadotropic hormone receptortarget
DB00033Interferon gamma-1bInterferon gamma receptor 1target
DB00033Interferon gamma-1bInterferon gamma receptor 2target
DB00034Interferon Alfa-2a, RecombinantInterferon alpha/beta receptor 1target
DB00034Interferon Alfa-2a, RecombinantInterferon alpha/beta receptor 2target
DB00035DesmopressinVasopressin V1a receptortarget
DB00035DesmopressinVasopressin V1b receptortarget
DB00035DesmopressinVasopressin V2 receptortarget
DB00035DesmopressinProstaglandin G/H synthase 1enzyme
DB00035DesmopressinProstaglandin G/H synthase 2enzyme
DB00038OprelvekinInterleukin-11 receptor subunit alphatarget
DB00039PaliferminFibroblast growth factor receptor 2target
DB00039PaliferminFibroblast growth factor receptor 1target
DB00039PaliferminFibroblast growth factor receptor 4target
DB00039PaliferminFibroblast growth factor receptor 3target
DB00039PaliferminBasement membrane-specific heparan sulfate proteoglycan core proteintarget
DB00040GlucagonGlucagon receptortarget
DB00040GlucagonGlucagon-like peptide 2 receptortarget
DB00040GlucagonGlucagon-like peptide 1 receptortarget
DB00041AldesleukinInterleukin-2 receptor subunit betatarget
DB00041AldesleukinInterleukin-2 receptor subunit alphatarget
DB00041AldesleukinCytokine receptor common subunit gammatarget
DB00041AldesleukinProstaglandin G/H synthase 2enzyme
DB00041AldesleukinCytosolic phospholipase A2enzyme
DB00041AldesleukinCytochrome P450 3A4enzyme
DB00041AldesleukinXanthine dehydrogenase/oxidaseenzyme
DB00041AldesleukinCytochrome P450 2E1enzyme
DB00046Insulin LisproInsulin receptortarget
DB00046Insulin LisproInsulin-like growth factor 1 receptortarget
DB00047Insulin glargineInsulin receptortarget
DB00047Insulin glargineInsulin-like growth factor 1 receptortarget
DB00050CetrorelixLutropin-choriogonadotropic hormone receptortarget
DB00050CetrorelixGonadotropin-releasing hormone receptortarget
DB00052SomatotropinGrowth hormone receptortarget
DB00052SomatotropinProlactin receptortarget
DB00054AbciximabIntegrin beta-3target
DB00054AbciximabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00054AbciximabComplement C1r subcomponenttarget
DB00054AbciximabComplement C1q subcomponent subunit Atarget
DB00054AbciximabComplement C1q subcomponent subunit Btarget
DB00054AbciximabComplement C1q subcomponent subunit Ctarget
DB00054AbciximabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00054AbciximabComplement C1s subcomponenttarget
DB00054AbciximabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00054AbciximabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00054AbciximabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00054AbciximabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00054AbciximabIntegrin alpha-IIbtarget
DB00057Indium In-111 satumomab pendetideTumor-associated glycoprotein 72 (TAG-72)target
DB00058Alpha-1-proteinase inhibitorNeutrophil elastasetarget
DB00060Interferon beta-1aInterferon alpha/beta receptor 1target
DB00060Interferon beta-1aInterferon alpha/beta receptor 2target
DB00066FollitropinFollicle-stimulating hormone receptortarget
DB00067VasopressinVasopressin V1a receptortarget
DB00067VasopressinVasopressin V2 receptortarget
DB00067VasopressinVasopressin V1b receptortarget
DB00067VasopressinCanalicular multispecific organic anion transporter 1transporter
DB00068Interferon beta-1bInterferon alpha/beta receptor 1target
DB00068Interferon beta-1bInterferon alpha/beta receptor 2target
DB00069Interferon alfacon-1Interferon alpha/beta receptor 1target
DB00069Interferon alfacon-1Interferon alpha/beta receptor 2target
DB00071Insulin PorkInsulin receptortarget
DB00071Insulin PorkHLA class II histocompatibility antigen, DQ alpha 2 chaintarget
DB00071Insulin PorkHLA class II histocompatibility antigen, DQ beta 1 chaintarget
DB00071Insulin PorkRetinoblastoma-associated proteintarget
DB00071Insulin PorkCathepsin Dtarget
DB00071Insulin PorkInsulin-like growth factor 1 receptortarget
DB00071Insulin PorkInsulin-degrading enzymetarget
DB00071Insulin PorkNeuroendocrine convertase 2target
DB00071Insulin PorkCarboxypeptidase Etarget
DB00071Insulin PorkNeuroendocrine convertase 1target
DB00071Insulin PorkProtein NOV homologtarget
DB00071Insulin PorkLow-density lipoprotein receptor-related protein 2target
DB00071Insulin PorkInsulin-like growth factor-binding protein 7target
DB00071Insulin PorkSynaptotagmin-like protein 4target
DB00080DaptomycinBacterial outer membranetarget
DB00080DaptomycinLipoteichoic acid synthesistarget
DB00082PegvisomantGrowth hormone receptortarget
DB00082PegvisomantSterol 26-hydroxylase, mitochondrialenzyme
DB00082PegvisomantGlutamine synthetaseenzyme
DB00082PegvisomantCytochrome P450 2C18enzyme
DB00082PegvisomantCytochrome P450 3A4enzyme
DB00082PegvisomantCytochrome P450 2C19enzyme
DB00082PegvisomantCytochrome P450 4A11enzyme
DB00093FelypressinVasopressin V1a receptortarget
DB00094UrofollitropinFollicle-stimulating hormone receptortarget
DB00102BecaplerminPlatelet-derived growth factor receptor betatarget
DB00102BecaplerminPlatelet-derived growth factor receptor alphatarget
DB00104OctreotideSomatostatin receptor type 1target
DB00104OctreotideSomatostatin receptor type 5target
DB00104OctreotideSomatostatin receptor type 2target
DB00104OctreotideCytochrome P450 3A4enzyme
DB00105Interferon alfa-2bInterferon alpha/beta receptor 2target
DB00105Interferon alfa-2bInterferon alpha/beta receptor 1target
DB00105Interferon alfa-2bCytochrome P450 1A2enzyme
DB00106AbarelixGonadotropin-releasing hormone receptortarget
DB00107OxytocinOxytocin-neurophysin 1target
DB00107OxytocinOxytocin receptortarget
DB00107OxytocinProlyl endopeptidaseenzyme
DB00109EnfuvirtideEnvelope glycoproteintarget
DB00109EnfuvirtideCytochrome P450 2C19enzyme
DB00109EnfuvirtideCytochrome P450 2E1enzyme
DB00143GlutathioneGlutathione reductase, mitochondrialtarget
DB00143GlutathioneGlutathione synthetasetarget
DB00143GlutathioneGlutathione S-transferase Mu 1target
DB00143GlutathioneGlutathione S-transferase kappa 1target
DB00143GlutathioneGlutathione S-transferase A3target
DB00143GlutathioneGlutathione S-transferase Mu 3target
DB00143GlutathioneGlutathione S-transferase A4target
DB00143GlutathioneGlutathione S-transferase Mu 4target
DB00143GlutathioneGlutathione S-transferase A5target
DB00143GlutathioneGlutathione S-transferase Ptarget
DB00143GlutathioneGlutathione S-transferase omega-1target
DB00143GlutathioneGlutathione peroxidase 1target
DB00143GlutathioneGlutathione peroxidase 2target
DB00143GlutathioneGlutathione S-transferase theta-1target
DB00143GlutathioneMaleylacetoacetate isomerasetarget
DB00143GlutathioneEpididymal secretory glutathione peroxidasetarget
DB00143GlutathioneGlutathione peroxidase 3target
DB00143GlutathioneLactoylglutathione lyasetarget
DB00143GlutathioneLeukotriene C4 synthasetarget
DB00143GlutathioneMicrosomal glutathione S-transferase 3target
DB00143GlutathioneHematopoietic prostaglandin D synthasetarget
DB00143GlutathioneThioredoxin domain-containing protein 12target
DB00143GlutathioneGlutathione S-transferase A1target
DB00143GlutathioneGlutathione S-transferase A2target
DB00143GlutathioneMicrosomal glutathione S-transferase 1target
DB00143GlutathioneS-formylglutathione hydrolasetarget
DB00143GlutathioneGamma-glutamyltranspeptidase 1target
DB00143GlutathioneGlutathione S-transferase Mu 2target
DB00143GlutathionePhospholipid hydroperoxide glutathione peroxidase, mitochondrialtarget
DB00143GlutathioneGlutathione S-transferase Mu 5target
DB00143GlutathioneGlutathione peroxidase 6target
DB00143GlutathioneHydroxyacylglutathione hydrolase, mitochondrialtarget
DB00143GlutathioneGlutathione peroxidasetarget
DB00143GlutathioneProbable glutathione peroxidase 8target
DB00143GlutathioneGlutathione peroxidase 7target
DB00143GlutathioneMicrosomal glutathione S-transferase 2target
DB00143GlutathioneGlutathione S-transferase omega-2target
DB00143GlutathioneGlutaredoxin-2, mitochondrialtarget
DB00143GlutathioneGlutathione S-transferase A2enzyme
DB00143GlutathioneGlutathione S-transferase A1enzyme
DB00143GlutathioneMultidrug resistance-associated protein 1transporter
DB00143GlutathioneCanalicular multispecific organic anion transporter 1transporter
DB00143GlutathioneCanalicular multispecific organic anion transporter 2transporter
DB00143GlutathioneMultidrug resistance-associated protein 4transporter
DB00143GlutathioneMultidrug resistance-associated protein 5transporter
DB00143GlutathioneAldose reductasetarget
DB00143GlutathioneMatrix metalloproteinase-9target
DB00143GlutathioneCytochrome P450 3A4target
DB00168AspartameTaste receptor type 1 member 2target
DB00168AspartameTransient receptor potential cation channel subfamily V member 1target
DB00168AspartameSolute carrier family 22 member 6transporter
DB00168AspartameSolute carrier family 22 member 8transporter
DB00168AspartameSolute carrier family 22 member 11transporter
DB00168AspartameTaste receptor type 1 member 3target
DB00183PentagastrinGastrin/cholecystokinin type B receptortarget
DB00290BleomycinDNA ligase 3target
DB00290BleomycinDNA ligase 1target
DB00290BleomycinBleomycin hydrolaseenzyme
DB00314Capreomycin70S ribosometarget
DB00362Anidulafungin1,3-beta-glucan synthase component FKS1target
DB00403CeruletideCholecystokinin receptor type Atarget
DB00512VancomycinD-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycantarget
DB00512VancomycinSerum albumincarrier
DB00512Vancomycinalpha1-acid glycoproteincarrier
DB00512VancomycinHistamine H1 receptorcarrier
DB00520CaspofunginSolute carrier family 22 member 1transporter
DB00520CaspofunginMultidrug resistance protein 1transporter
DB00520CaspofunginSolute carrier family 22 member 6transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B1transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B3transporter
DB00520CaspofunginCytochrome P450 3A4enzyme
DB00520Caspofungin1,3-beta-glucan synthase component FKS1target
DB00584EnalaprilAngiotensin-converting enzymetarget
DB00584EnalaprilCytochrome P450 3A4enzyme
DB00584EnalaprilMultidrug resistance protein 1transporter
DB00584EnalaprilSolute carrier family 15 member 1transporter
DB00584EnalaprilSolute carrier family 22 member 6transporter
DB00584EnalaprilSolute carrier family 22 member 8transporter
DB00584EnalaprilSolute carrier family 22 member 7transporter
DB00584EnalaprilSolute carrier organic anion transporter family member 1A2transporter
DB00626BacitracinInsulin-degrading enzymetarget
DB00626BacitracinC55-isoprenyl pyrophosphatetarget
DB00644GonadorelinGonadotropin-releasing hormone receptortarget
DB00644GonadorelinPutative gonadotropin-releasing hormone II receptortarget
DB00666NafarelinGonadotropin-releasing hormone receptortarget
DB00666NafarelinPutative gonadotropin-releasing hormone II receptortarget
DB00722LisinoprilAngiotensin-converting enzymetarget
DB00803ColistinBacterial outer membranetarget
DB00855Aminolevulinic acidDelta-aminolevulinic acid dehydratasetarget
DB00855Aminolevulinic acidSolute carrier family 15 member 1transporter
DB00855Aminolevulinic acidSolute carrier family 15 member 2transporter
DB00970DactinomycinSolute carrier family 22 member 5transporter
DB00970DactinomycinMultidrug resistance protein 1transporter
DB00970DactinomycinMultidrug resistance-associated protein 6transporter
DB00970DactinomycinMultidrug resistance-associated protein 1transporter
DB00970DactinomycinATP-binding cassette sub-family G member 2transporter
DB00970DactinomycinDNA topoisomerase 2target
DB01072AtazanavirHuman immunodeficiency virus type 1 proteasetarget
DB01072AtazanavirCytochrome P450 3A4enzyme
DB01072AtazanavirCytochrome P450 2C9enzyme
DB01072AtazanavirMultidrug resistance protein 1transporter
DB01072AtazanavirMultidrug resistance-associated protein 1transporter
DB01072AtazanavirSerum albumincarrier
DB01072AtazanavirUDP-glucuronosyltransferase 1-1enzyme
DB01072AtazanavirSolute carrier organic anion transporter family member 1B1transporter
DB01072AtazanavirSolute carrier organic anion transporter family member 1B3transporter
DB01072AtazanavirCytochrome P450 2C8enzyme
DB01072AtazanavirBile salt export pumptransporter
DB01111ColistimethateBacterial outer membranetarget
DB01141MicafunginArylsulfatase Aenzyme
DB01141MicafunginCatechol O-methyltransferaseenzyme
DB01141Micafungin1,3-beta-glucan synthase component FKS1target
DB01277MecaserminInsulin-like growth factor 1 receptortarget
DB01277MecaserminInsulin-like growth factor-binding protein 3target
DB01277MecaserminInsulin receptortarget
DB01277MecaserminCation-independent mannose-6-phosphate receptortarget
DB01277MecaserminInsulin-like growth factor-binding protein 3carrier
DB01277MecaserminInsulin-like growth factor-binding protein complex acid labile subunitcarrier
DB01277MecaserminInsulin-like growth factor-binding protein 1carrier
DB01277MecaserminInsulin-like growth factor-binding protein 2carrier
DB01277MecaserminInsulin-like growth factor-binding protein 4carrier
DB01277MecaserminInsulin-like growth factor-binding protein 5carrier
DB01277MecaserminInsulin-like growth factor-binding protein 6carrier
DB01278PramlintideReceptor activity-modifying protein 1target
DB01278PramlintideReceptor activity-modifying protein 2target
DB01278PramlintideReceptor activity-modifying protein 3target
DB01278PramlintideCalcitonin receptortarget
DB01282CarbetocinOxytocin receptortarget
DB01284TetracosactideAdrenocorticotropic hormone receptortarget
DB01285CorticotropinAdrenocorticotropic hormone receptortarget
DB01285Corticotropin3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
DB01285Corticotropin25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
DB01285Corticotropin1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB01285CorticotropinCytochrome P450 3A4enzyme
DB01306Insulin AspartInsulin receptortarget
DB01306Insulin AspartInsulin-like growth factor 1 receptortarget
DB01307Insulin DetemirInsulin receptortarget
DB01307Insulin DetemirSerum albumincarrier
DB01307Insulin DetemirInsulin-like growth factor 1 receptortarget
DB01309Insulin GlulisineInsulin receptortarget
DB01309Insulin GlulisineInsulin-like growth factor 1 receptortarget
DB01348SpiraprilAngiotensin-converting enzymetarget
DB01348SpiraprilSolute carrier family 15 member 1transporter
DB01348SpiraprilSolute carrier family 15 member 2transporter
DB01369Quinupristin23S rRNAtarget
DB01369Quinupristin50S ribosomal protein L10target
DB01369Quinupristin50S ribosomal protein L22target
DB01369QuinupristinCytochrome P450 3A4enzyme
DB01669Virginiamycin M1Streptogramin A acetyltransferasetarget
DB01683ChymostatinPeptide amidasetarget
DB01764DalfopristinStreptogramin A acetyltransferasetarget
DB01764DalfopristinCytochrome P450 3A4enzyme
DB02083N,N-dimethylglycineMonomeric sarcosine oxidasetarget
DB02123Glycochenodeoxycholic Acid7-alpha-hydroxysteroid dehydrogenasetarget
DB02123Glycochenodeoxycholic AcidBile salt export pumptransporter
DB02123Glycochenodeoxycholic AcidSolute carrier organic anion transporter family member 1A2transporter
DB02123Glycochenodeoxycholic AcidIleal sodium/bile acid cotransportertransporter
DB02123Glycochenodeoxycholic AcidSodium/bile acid cotransportertransporter
DB02255GM6001Lethal factortarget
DB02255GM6001Disintegrin and metalloproteinase domain-containing protein 28target
DB02255GM6001Aggrecan core proteintarget
DB02341Mdl 101,146Chymotrypsin-like elastase family member 1target
DB02341Mdl 101,146Neutrophil elastasetarget
DB02557PhosphoramidonKell blood group glycoproteintarget
DB02578Glycyl-L-Alpha-Amino-Epsilon-Pimelyl-D-Alanyl-D-AlanineD-alanyl-D-alanine carboxypeptidasetarget
DB02638TerlipressinVasopressin V1a receptortarget
DB02638TerlipressinVasopressin V2 receptortarget
DB02638TerlipressinVasopressin V1b receptortarget
DB02855N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-ProlineCathepsin Btarget
DB02975GE-2270AElongation factor Tutarget
DB03032S-OctylglutathioneGlutathione S-transferase Mu 4target
DB03408gamma-GlutamylcysteineGlutathione synthetasetarget
DB03436GallichromeIron(3+)-hydroxamate-binding protein FhuDtarget
DB03470TrypanothioneTrypanothione reductasetarget
DB03535Z-Pro-ProlinalProlyl endopeptidasetarget
DB03535Z-Pro-ProlinalProlyl endopeptidasetarget
DB03889S-(N-Hydroxy-N-Bromophenylcarbamoyl)GlutathioneHydroxyacylglutathione hydrolase, mitochondrialtarget
DB04132S-HexylglutathioneLactoylglutathione lyasetarget
DB04132S-HexylglutathioneGlutathione S-transferase Mu 4target
DB04132S-HexylglutathioneGlutathione S-transferase Ptarget
DB04132S-HexylglutathioneGlutathione S-transferasetarget
DB04132S-HexylglutathioneGlutathione S-transferase A1target
DB04132S-HexylglutathioneGlutathione S-transferase theta-2target
DB04132S-HexylglutathioneGlutathione S-transferase A1enzyme
DB04191Skf 107457Gag-Pol polyproteintarget
DB04269Cyclotheonamide ATrypsin-1target
DB04391Aeruginosin 98-BTrypsin-1target
DB04738MotuporinSerine/threonine-protein phosphatase PP1-gamma catalytic subunittarget
DB04805Virginiamycin S160S ribosomal protein L37target
DB04869OlcegepantCalcitonin gene-related peptide 1target
DB04869OlcegepantCalcitonin gene-related peptide type 1 receptortarget
DB04894VapreotideSubstance-P receptortarget
DB04894VapreotideSomatostatin receptor type 2target
DB04894VapreotideSomatostatin receptor type 5target
DB04894VapreotideCytochrome P450 3A4enzyme
DB04899NesiritideAtrial natriuretic peptide receptor 1target
DB04899NesiritideAtrial natriuretic peptide receptor 2target
DB04899NesiritideAtrial natriuretic peptide receptor 3target
DB04911OritavancinCytochrome P450 3A4enzyme
DB04911OritavancinCytochrome P450 2D6enzyme
DB04911OritavancinCytochrome P450 2C9enzyme
DB04911OritavancinCytochrome P450 2C19enzyme
DB04931AfamelanotideMelanocyte-stimulating hormone receptortarget
DB04972CanfosfamideGlutathione S-transferase Ptarget
DB04977PlitidepsinCytochrome P450 3A4enzyme
DB04977PlitidepsinCytochrome P450 2A6enzyme
DB04977PlitidepsinCytochrome P450 2E1enzyme
DB04977PlitidepsinCytochrome P450 4A11enzyme
DB04985Tigapotide40S ribosomal protein SAtarget
DB05029LancovutideCytosolic phospholipase A2enzyme
DB05034UlaritideAtrial natriuretic peptide receptor 1target
DB05084AbaloparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget
DB05098LeptinLeptin receptortarget
DB05115NN344Insulin receptortarget
DB05155CR665Kappa-type opioid receptortarget
DB05161ElafinNeutrophil elastasetarget
DB05210SF1126Phosphatidylinositol 3-kinase regulatory subunit alphatarget
DB05210SF1126Phosphatidylinositol 3-kinase regulatory subunit betatarget
DB05210SF1126Phosphatidylinositol 3-kinase regulatory subunit gammatarget
DB05210SF1126DNA-dependent protein kinase catalytic subunittarget
DB05210SF1126Serine/threonine-protein kinase mTORtarget
DB05258Interferon alfaInterferon alpha/beta receptor 1target
DB05259GlatiramerHLA class II histocompatibility antigen, DRB1-1 beta chaintarget
DB05305Cintredekin BesudotoxInterleukin-13target
DB05332RomiplostimThrombopoietin receptortarget
DB05394CorticorelinDopamine beta-hydroxylaseenzyme
DB05413TifuvirtidePlasma serine protease inhibitortarget
DB05434ABT-510Fibroblast growth factor 2target
DB05434ABT-510Hepatocyte growth factortarget
DB05434ABT-510Vascular endothelial growth factor Atarget
DB05460EzatiostatGlutathione S-transferase Ptarget
DB05475GolotimodToll-like receptor 2target
DB05475GolotimodToll-like receptor 4target
DB05475GolotimodToll-like receptor 7target
DB05475GolotimodToll-like receptor 9target
DB05507VX-765Interleukin-1 betatarget
DB05521TelaprevirCytochrome P450 3A4enzyme
DB05521TelaprevirNS3/4A proteintarget
DB05521TelaprevirMultidrug resistance protein 1transporter
DB05521TelaprevirSerum albumincarrier
DB05521TelaprevirAlpha-1-acid glycoprotein 1carrier
DB05521TelaprevirSolute carrier organic anion transporter family member 1B1target
DB05521TelaprevirSolute carrier organic anion transporter family member 2B1target
DB05521TelaprevirCytochrome P450 3A5enzyme
DB05739CYT006-AngQbType-1 angiotensin II receptortarget
DB05739CYT006-AngQbType-2 angiotensin II receptortarget
DB05793PRO-542Free fatty acid receptor 4target
DB05829Parathyroid hormoneParathyroid hormone/parathyroid hormone-related peptide receptortarget
DB05829Parathyroid hormoneParathyroid hormone 2 receptortarget
DB05931PegdinetanibVascular endothelial growth factor receptor 2target
DB05934CTCE-0214Stromal cell-derived factor 1target
DB06081Caplacizumabvon Willebrand factortarget
DB06138IRL-1620Endothelin B receptortarget
DB06149TeicoplaninD-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycantarget
DB06176RomidepsinCytochrome P450 3A4enzyme
DB06176RomidepsinCytochrome P450 3A5enzyme
DB06176RomidepsinMultidrug resistance protein 1transporter
DB06176RomidepsinSolute carrier organic anion transporter family member 1B3transporter
DB06176RomidepsinCytochrome P450 1A1enzyme
DB06176RomidepsinCytochrome P450 2B6enzyme
DB06176RomidepsinCytochrome P450 2C19enzyme
DB06176RomidepsinHistone deacetylase 1target
DB06176RomidepsinHistone deacetylase 2target
DB06176RomidepsinHistone deacetylase 4target
DB06176RomidepsinHistone deacetylase 6target
DB06176RomidepsinMultidrug resistance-associated protein 1target
DB06196IcatibantB2 bradykinin receptortarget
DB06196IcatibantAminopeptidase Ntarget
DB06219DalbavancinD-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycantarget
DB06285TeriparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget
DB06335SaxagliptinDipeptidyl peptidase 4target
DB06335SaxagliptinCytochrome P450 3A4enzyme
DB06335SaxagliptinCytochrome P450 3A5enzyme
DB06335SaxagliptinMultidrug resistance-associated protein 1transporter
DB06335SaxagliptinSolute carrier organic anion transporter family member 4C1transporter
DB06335SaxagliptinSolute carrier family 22 member 8transporter
DB06404Human C1-esterase inhibitorComplement C1r subcomponenttarget
DB06404Human C1-esterase inhibitorComplement C1s subcomponenttarget
DB06404Human C1-esterase inhibitorPlasma kallikreintarget
DB06404Human C1-esterase inhibitorCoagulation factor XIItarget
DB06404Human C1-esterase inhibitorProthrombintarget
DB06404Human C1-esterase inhibitorCoagulation factor XItarget
DB06404Human C1-esterase inhibitorTissue-type plasminogen activatortarget
DB06423Endostatin72 kDa type IV collagenasetarget
DB06423EndostatinMatrix metalloproteinase-9target
DB06423EndostatinCollagenase 3target
DB06423EndostatinFocal adhesion kinase 1target
DB06423EndostatinCytochrome P450 19A1enzyme
DB06534ThrombopoietinThrombopoietin receptortarget
DB06549LabradimilB2 bradykinin receptortarget
DB06655LiraglutideGlucagon-like peptide 1 receptortarget
DB06655LiraglutideDipeptidyl peptidase 4enzyme
DB06655LiraglutideSerum albumincarrier
DB06663PasireotideSomatostatin receptor type 1target
DB06663PasireotideSomatostatin receptor type 2target
DB06663PasireotideSomatostatin receptor type 3target
DB06663PasireotideSomatostatin receptor type 5target
DB06663PasireotideCytochrome P450 3A4enzyme
DB06699DegarelixGonadotropin-releasing hormone receptortarget
DB06719BuserelinLutropin-choriogonadotropic hormone receptortarget
DB06719BuserelinGonadotropin-releasing hormone receptortarget
DB06719BuserelinCytochrome P450 19A1enzyme
DB06785GanirelixGonadotropin-releasing hormone receptortarget
DB06788HistrelinGonadotropin-releasing hormone receptortarget
DB06791LanreotideSomatostatin receptor type 2target
DB06791LanreotideSomatostatin receptor type 5target
DB06791LanreotideCytochrome P450 3A4enzyme
DB06825TriptorelinGonadotropin-releasing hormone receptortarget
DB06827Viomycin70S ribosometarget
DB08856DADLESolute carrier organic anion transporter family member 1B1transporter
DB08861DPDPESolute carrier organic anion transporter family member 1B3transporter
DB08862CholecystokininSolute carrier organic anion transporter family member 1B3transporter
DB08862CholecystokininCholecystokinin receptor type Atarget
DB08862CholecystokininRAF proto-oncogene serine/threonine-protein kinasetarget
DB08862CholecystokininMitogen-activated protein kinase 3target
DB08862CholecystokininPro-epidermal growth factortarget
DB08862CholecystokininProtein kinase C beta typetarget
DB08862CholecystokininGastrin/cholecystokinin type B receptortarget
DB08862CholecystokininSolute carrier organic anion transporter family member 1B1transporter
DB08862CholecystokininSolute carrier organic anion transporter family member 2B1transporter
DB08869TesamorelinGrowth hormone-releasing hormone receptortarget
DB08889CarfilzomibMultidrug resistance protein 1transporter
DB08889CarfilzomibProteasome subunit beta type-5target
DB08889CarfilzomibProteasome subunit beta type-9target
DB08889CarfilzomibProteasome subunit beta type-10target
DB08889CarfilzomibProteasome subunit beta type-8target
DB08889CarfilzomibProteasome subunit beta type-1target
DB08889CarfilzomibProteasome subunit beta type-2target
DB08900TeduglutideGlucagon-like peptide 2 receptortarget
DB08904Certolizumab pegolTumor necrosis factortarget
DB08904Certolizumab pegolAlcohol dehydrogenase [NADP(+)]enzyme
DB09043AlbiglutideGlucagon-like peptide 1 receptortarget
DB09045DulaglutideGlucagon-like peptide 1 receptortarget
DB09046MetreleptinLeptin receptortarget
DB09059AtosibanOxytocin receptortarget
DB09059AtosibanVasopressin V1a receptortarget
DB09059AtosibanVasopressin V1b receptortarget
DB09059AtosibanVasopressin V2 receptortarget
DB09066Corifollitropin alfaFollicle-stimulating hormone receptortarget
DB09067Corticorelin ovine triflutateCorticotropin-releasing factor receptor 1target
DB09098SomatremGrowth hormone receptortarget
DB09098SomatremInsulin-like growth factor 1 receptortarget
DB09099SomatostatinSomatostatin receptor type 1target
DB09099SomatostatinSomatostatin receptor type 2target
DB09099SomatostatinSomatostatin receptor type 3target
DB09099SomatostatinSomatostatin receptor type 4target
DB09099SomatostatinSomatostatin receptor type 5target
DB09099SomatostatinMultidrug resistance protein 1transporter
DB09099SomatostatinCytochrome P450 3A4enzyme
DB09103AncestimMast/stem cell growth factor receptor Kittarget
DB09107Methoxy polyethylene glycol-epoetin betaErythropoietin receptortarget
DB09126Chorionic Gonadotropin (Human)Lutropin-choriogonadotropic hormone receptortarget
DB09142SincalideSolute carrier organic anion transporter family member 1B3transporter
DB09221PolaprezincTumor necrosis factortarget
DB09221PolaprezincSuperoxide dismutase [Cu-Zn]enzyme
DB09221PolaprezincHeme oxygenase 1enzyme
DB09221PolaprezincSuperoxide dismutase [Mn], mitochondrialenzyme
DB09221PolaprezincGlutathione S-transferase theta-1enzyme
DB09221PolaprezincGlutathione peroxidase 1enzyme
DB09221PolaprezincPeroxiredoxin-5, mitochondrialenzyme
DB09221PolaprezincVascular endothelial growth factor receptor 1target
DB09221PolaprezincBeta-nerve growth factortarget
DB09221PolaprezincPlatelet-derived growth factor receptor betatarget
DB09221PolaprezincHeat shock protein HSP 90-alphatarget
DB09221PolaprezincHeat shock protein HSP 90-betatarget
DB09421ProtirelinThyrotropin Releasing Hormone Receptortarget
DB09477EnalaprilatAngiotensin-converting enzymetarget
DB09477EnalaprilatB1 bradykinin receptortarget
DB09564Insulin DegludecInsulin receptortarget
DB09564Insulin DegludecInsulin-like growth factor 1 receptortarget
DB09564Insulin DegludecSerum albumincarrier
DB11095DesirudinCarboxypeptidase A1enzyme
DB11598Antithrombin III humanAntithrombin-IIItarget
DB11639Dibotermin alfaBone morphogenetic protein receptor type-1Atarget
DB11639Dibotermin alfaBone morphogenetic protein receptor type-2target
DB11842Angiotensin IIType-1 angiotensin II receptortarget
DB11854AstodrimerEnvelope glycoprotein gp160target
DB11869ValspodarSolute carrier organic anion transporter family member 1B1transporter
DB11869ValspodarSolute carrier organic anion transporter family member 1B3transporter
DB13074MacimorelinGrowth hormone secretagogue receptor type 1target
DB13074MacimorelinCytochrome P450 3A4enzyme
DB13144LenograstimGranulocyte colony-stimulating factor receptortarget
DB13200LipegfilgrastimGranulocyte colony-stimulating factor receptortarget
DB13503TyrothricinPhospholipid membranetarget
DB13615MifamurtideToll-like receptor 4target
DB13615MifamurtideNucleotide-binding oligomerization domain-containing protein 2target
DB13928SemaglutideSerum albumincarrier
DB13928SemaglutideDipeptidyl peptidase 4enzyme
DB13928SemaglutideGlucagon-like peptide 1 receptortarget
DB13928SemaglutideSolute carrier organic anion transporter family member 1B1transporter
DB13928SemaglutideSolute carrier organic anion transporter family member 1B3transporter
DB13928SemaglutideLipoprotein lipaseenzyme
DB13928SemaglutideAlpha-amylase 1enzyme
DB13985Lutetium Lu 177 dotatateSomatostatin receptor type 2target
DB13985Lutetium Lu 177 dotatateSomatostatin receptor type 1target
DB13985Lutetium Lu 177 dotatateSomatostatin receptor type 3target
DB13985Lutetium Lu 177 dotatateSomatostatin receptor type 4target
DB13985Lutetium Lu 177 dotatateSomatostatin receptor type 5target
DB05624TeverelixGonadotropin-releasing hormone receptortarget
DB14057ValinomycinBile salt export pumptransporter
DB14058BasifunginInositol phosphorylceramide synthasetarget
DB14072Reversin 121Multidrug resistance protein 1target
DB00099FilgrastimGranulocyte colony-stimulating factor receptortarget
DB00099FilgrastimNeutrophil elastasetarget
DB09532Secretin humanSecretin receptortarget
DB14642LypressinVasopressin V1a receptortarget
DB14642LypressinVasopressin V2 receptortarget
DB14642LypressinVasopressin V1b receptortarget
DB14642LypressinCanalicular multispecific organic anion transporter 1transporter
DB07558acetylleucyl-leucyl-norleucinalProteasome subunit alpha type-7target
DB02458S-(2,4-dinitrophenyl)glutathioneGlutathione S-transferase Mu 1target
DB02458S-(2,4-dinitrophenyl)glutathioneGlutathione S-transferase Mu 2target
DB02691Glycocholic acidGastrotropintarget
DB02691Glycocholic acidSolute carrier organic anion transporter family member 1A2transporter
DB02691Glycocholic acidSolute carrier organic anion transporter family member 1B1transporter
DB02691Glycocholic acidSolute carrier organic anion transporter family member 1B3transporter
DB03310Glutathione disulfideGlutathione S-transferase Mu 2target
DB03310Glutathione disulfideGlutathione reductase, mitochondrialtarget
DB11693VoclosporinCalcineurin subunit B type 1target
DB11693VoclosporinCalcineurin subunit B type 2target
DB13170PlecanatideGuanylate cyclase soluble subunit alpha-2target
DB05004Peptide YY (3-36)Neuropeptide Y receptor type 2target
DB05004Peptide YY (3-36)Neuropeptide Y receptor type 1target
DB05004Peptide YY (3-36)Neuropeptide Y receptor type 5target
DB05004Peptide YY (3-36)Neuropeptide Y receptor type 4target
DB00091CiclosporinCalcium signal-modulating cyclophilin ligandtarget
DB00091CiclosporinPeptidyl-prolyl cis-trans isomerase Atarget
DB00091CiclosporinCalcineurin subunit B type 2target
DB00091CiclosporinCytochrome P450 3A5enzyme
DB00091CiclosporinCytochrome P450 3A4enzyme
DB00091CiclosporinCytochrome P450 3A7enzyme
DB00091CiclosporinMultidrug resistance protein 1transporter
DB00091CiclosporinCanalicular multispecific organic anion transporter 2transporter
DB00091CiclosporinBile salt export pumptransporter
DB00091CiclosporinSolute carrier organic anion transporter family member 1A2transporter
DB00091CiclosporinIleal sodium/bile acid cotransportertransporter
DB00091CiclosporinSodium/bile acid cotransportertransporter
DB00091CiclosporinSolute carrier family 22 member 6transporter
DB00091CiclosporinMultidrug resistance-associated protein 7transporter
DB00091CiclosporinCanalicular multispecific organic anion transporter 1transporter
DB00091CiclosporinATP-binding cassette sub-family G member 2transporter
DB00091CiclosporinSolute carrier organic anion transporter family member 1B1transporter
DB00091CiclosporinCytochrome P450 2C19enzyme
DB00091CiclosporinCytochrome P450 2C8enzyme
DB00091CiclosporinCytochrome P450 2C9enzyme
DB00091CiclosporinCytochrome P450 2D6enzyme
DB00091CiclosporinPeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00091CiclosporinSolute carrier organic anion transporter family member 1B3transporter
DB00781Polymyxin BBacterial outer membranetarget
DB00781Polymyxin BSolute carrier family 15 member 2transporter
DB05386RegramostimGranulocyte-macrophage colony-stimulating factor receptor subunit alphatarget
DB05386RegramostimGM-CSF receptor alpha subunittarget
DB05875Sar9, Met (O2)11-Substance PCytochrome P450 19A1enzyme
DB05875Sar9, Met (O2)11-Substance PCholinesteraseenzyme
DB05875Sar9, Met (O2)11-Substance PProstaglandin G/H synthase 2enzyme