Biological Factors

Endogenously-synthesized compounds that influence biological processes not otherwise classified under ENZYMES; HORMONES or HORMONE ANTAGONISTS.
DrugDrug NameDrug Indication
DB00004Denileukin diftitoxFor treatment of cutaneous T-cell lymphoma
DB00005EtanerceptEtanercept is indicated for the treatment of moderately to severely active rheumatoid arthritis in adults and chronic moderate to severe plaque psoriasis in adults. It is also used to manage signs and symptoms of polyarticular idiopathic arthritis in those aged 4 to 17 after insufficient response to one or more disease-modifying anti-rheumatic drugs. Etanercept is also used to improve psoriatic arthritis and ankylosing spondylitis.
DB00008Peginterferon alfa-2aPeginterferon alfa-2a is indicated for the treatment of HCV in combination with other antiviral drugs in patients over 5 years of age with compensated liver disease [FDA Label]. May be used as a monotherapy in patients with contraindications to or significant intolerance to other anti-viral therapies. Peginterferon alfa-2a is also indicated as a monotherapy for adult patients with HBeAg positive and HBeAg negative chronic hepatitis B infection who have compensated liver disease and evidence of viral replication and liver inflammation [FDA Label].
DB00009AlteplaseFor management of acute myocardial infarction, acute ischemic strok and for lysis of acute pulmonary emboli
DB00011Interferon alfa-n1For treatment of venereal or genital warts caused by the Human Papiloma Virus
DB00012Darbepoetin alfaFor the treatment of anemia (from renal transplants or certain HIV treatment)
DB00013UrokinaseUrokinase can be used for the treatment of pulminary embolism, coronary artery thrombosis, IV catheter clearance, and venous and arterial blood clots.
DB00015ReteplaseFor lysis of acute pulmonary emboli, intracoronary emboli and management of myocardial infarction
DB00016ErythropoietinFor use in the treatment of symptomatic anaemia associated with chronic renal failure (CRF) in adult and paediatric patients. Also for use in the treatment of anaemia and reduction of transfusion requirements in adult patients receiving chemotherapy for solid tumours, malignant lymphoma or multiple myeloma, and at risk of transfusion as assessed by the patient's general status (e.g. cardiovascular status, pre-existing anaemia at the start of chemotherapy). Also for used to increase the yield of autologous blood from patients in a predonation program. When administered subcutaneously, Epoetin Zeta is equivalent to Epoetin Alfa in terms of clinical effectiveness.
DB00018Interferon alfa-n3For the intralesional treatment of refractory or recurring external condylomata acuminata.
DB00019PegfilgrastimIncreases leukocyte production, for treatment in non-myeloid cancer, neutropenia and bone marrow transplant.
DB00020SargramostimFor the treatment of cancer and bone marrow transplant
DB00022Peginterferon alfa-2bPeginterferon alfa-2b is indicated for the treatment of HCV in combination with [DB00811] and a NS3/4A protease inhibitor for genotype 1 or without a NS3/4A protease inhibitor for genotypes 2-6 [FDA Label]. May be used as a monotherapy in patients with contraindications to or significant intolerance to other anti-viral therapies.
DB00025Antihemophilic factor, human recombinantFor the treatment of hemophilia A, von Willebrand disease and Factor XIII deficiency.
DB00026AnakinraFor the treatment of adult rheumatoid arthritis and treatment of Neonatal-Onset Multisystem Inflammatory Disease (NOMID).
DB00029AnistreplaseFor lysis of acute pulmonary emboli, intracoronary emboli and management of myocardial infarction
DB00031TenecteplaseFor treatment of myocardial infarction and lysis of intracoronary emboli
DB00033Interferon gamma-1bInterferon gamma-1b is used for the treatment of Chronic granulomatous disease and Osteopetrosis.
DB00034Interferon Alfa-2a, RecombinantFor the treatment of chronic hepatitis C, hairy cell leukemia, AIDS-related Kaposi's sarcoma, and chronic myelogenous leukemia. Also for the treatment of oral warts arising from HIV infection.
DB00036Coagulation factor VIIa Recombinant HumanFor treatment of hemorrhagic complications in hemophilia A and B
DB00038OprelvekinIncreases reduced platelet levels due to chemotherapy
DB00039PaliferminFor treatment of oral mucositis associated with chemotherapy and radiation therapy.
DB00041AldesleukinFor treatment of adults with metastatic renal cell carcinoma.
DB00042Botulinum Toxin Type BFor the treatment of patients with cervical dystonia to reduce the severity of abnormal head position and neck pain associated with cervical dystonia.
DB00055Drotrecogin alfaFor reduction of mortality in patients with severe sepsis.
DB00060Interferon beta-1aFor treatment of relapsing/remitting multiple sclerosis, also for condyloma acuminatum
DB00068Interferon beta-1bInterferon beta-1b is a drug used for the treatment of relapsing/remitting multiple sclerosis. It has been shown to slow the advance of the disease as well as to decrease the frequency of attacks.
DB00069Interferon alfacon-1For the treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma
DB00070HyaluronidaseFor increase of absorption and distribution of other injected drugs and for rehydration.
DB00083Botulinum Toxin Type AFor the treatment of cervical dystonia in adults to decrease the severity of abnormal head position and neck pain associated with cervical dystonia. Also for the treatment of severe primary axillary hyperhidrosis that is inadequately managed with topical agents and for the treatment of strabismus and blepharospasm associated with dystonia, including benign essential blepharospasm or VII nerve disorders in patients 12 years of age and above. Also used cosmetically to temporarily improve the appearance of moderate-to-severe frown lines between the eyebrows (glabellar lines) as well as for the treatment of excessive underarm sweating.
DB00086StreptokinaseFor the treatment of acute evolving transmural myocardial infarction, pulmonary embolism, deep vein thrombosis, arterial thrombosis or emolism and occlusion of arteriovenous cannulae
DB00099FilgrastimFilgrastim is used in patients with acute myeloid leukemia receiving induction or consolidation chemotherapy. It is also used in cancer patients receiving bone marrow transplant. In general, filgrastim increases neutrophil counts in order to decrease the risk of infection or duration of neutropenia in the aforementioned patient populations. Infection and neutropenia are adverse events associated with chemotherapy. Furthermore, filgrastim is also indicated for patients with severe chronic neutropenia. It mobilizes hematopoietic progenitor cells into the peripheral blood for collection by leukapheresis to allow for a more rapid engraftment. Tbo-filgrastim has a narrower indication profile than Neupogen - it is a leukocyte growth factor indicated for the reduction in the duration of severe neutropenia in patients with non-myeloid malignancies.
DB00102BecaplerminFor topical treatment of skin ulcers (from diabetes)
DB00105Interferon Alfa-2b, RecombinantFor the treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma.
DB00109EnfuvirtideEnfuvirtide is an antiretroviral drug used in combination therapy for the treatment of HIV-1/AIDS.
DB00116Tetrahydrofolic acidFor nutritional supplementation, also for treating dietary shortage or imbalance.
DB00140RiboflavinFor the treatment of ariboflavinosis (vitamin B2 deficiency).
DB00154Dihomo-gamma-linolenic acidFor nutritional supplementation, also for treating dietary shortage or imbalance
DB00158Folic AcidFor treatment of folic acid deficiency, megaloblastic anemia and in anemias of nutritional supplements, pregnancy, infancy, or childhood.
DB00159IcosapentEPA can be used for lowering elevated triglycerides in those who are hyperglyceridemic. In addition, EPA may play a therapeutic role in patients with cystic fibrosis by reducing disease severity and may play a similar role in type 2 diabetics in slowing the progression of diabetic nephropathy.
DB00162Vitamin AFor the treatment of vitamin A deficiency.
DB00287TravoprostOphthalmic solution used for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication.
DB00360SapropterinFor the treatment of tetrahydrobiopterin (BH4) deficiency.
DB00374TreprostinilFor use as a continuous subcutaneous infusion or intravenous infusion (for those not able to tolerate a subcutaneous infusion) for the treatment of pulmonary arterial hypertension in patients with NYHA Class II-IV symptoms to diminish symptoms associated with exercise.
DB00429Carboprost TromethamineFor aborting pregnancy between the 13th and 20th weeks of gestation as calculated from the first day of the last normal menstrual period and in the following conditions related to second trimester abortion: 1. Failure of expulsion of the fetus during the course of treatment by another method; 2. Premature rupture of membranes in intrauterine methods with loss of drug and insufficient or absent uterine activity; 3. Requirement of a repeat intrauterine instillation of drug for expulsion of the fetus; 4. Inadvertent or spontaneous rupture of membranes in the presence of a previable fetus and absence of adequate activity for expulsion. Also for the treatment of postpartum hemorrhage due to uterine atony which has not responded to conventional methods of management.
DB00459AcitretinFor the treatment of severe psoriasis in adults.
DB00460VerteporfinFor the treatment of patients with predominantly classic subfoveal choroidal neovascularization due to age-related macular degeneration, pathologic myopia or presumed ocular histoplasmosis syndrome. Verteporfin can also be used to destroy tumors.
DB00523AlitretinoinFor topical treatment of cutaneous lesions in patients with AIDS-related Kaposi's sarcoma.
DB00553MethoxsalenFor the treatment of psoriasis and vitiligo
DB00563MethotrexateMethotrexate is indicated in the treatment of gestational choriocarcinoma, chorioadenoma destruens and hydatidiform mole. In acute lymphocytic leukemia, methotrexate is indicated in the prophylaxis of meningeal leukemia and is used in maintenance therapy in combination with other chemotherapeutic agents. Methotrexate is also indicated in the treatment of meningeal leukemia. Methotrexate is used alone or in combination with other anticancer agents in the treatment of breast cancer, epidermoid cancers of the head and neck, advanced mycosis fungoides (cutaneous T cell lymphoma), and lung cancer, particularly squamous cell and small cell types. Methotrexate is also used in combination with other chemotherapeutic agents in the treatment of advanced stage non-Hodgkin’s lymphomas. Methotrexate is indicated in the symptomatic control of severe, recalcitrant, disabling psoriasis. Methotrexate is indicated in the management of selected adults with severe, active rheumatoid arthritis (ACR criteria), or children with active polyarticular-course juvenile rheumatoid arthritis.
DB00640AdenosineUsed as an initial treatment for the termination of paroxysmal supraventricular tachycardia (PVST), including that associated with accessory bypass tracts, and is a drug of choice for terminating stable, narrow-complex supraventricular tachycardias (SVT). Also used as an adjunct to thallous chloride TI 201 myocardial perfusion scintigraphy (thallium stress test) in patients who are unable to exercise adequately, as well as an adjunct to vagal maneuvers and clinical assessment to establish a specific diagnosis of undefined, stable, narrow-complex SVT.
DB00650LeucovorinFor the treatment of osteosarcoma (after high dose methotrexate therapy). Used to diminish the toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosages of folic acid antagonists, and to treat megaloblastic anemias due to folic acid deficiency. Also used in combination with 5-fluorouracil to prolong survival in the palliative treatment of patients with advanced colorectal cancer.
DB00654LatanoprostFor the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
DB00707Porfimer sodiumIndicated in the treatment of esophageal cancer.
DB00755TretinoinFor the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage.
DB00770AlprostadilFor palliative, not definitive, therapy to temporarily maintain the patency of the ductus arteriosus until corrective or palliative surgery can be performed in neonates who have congenital heart defects and who depend upon the patent ductus for survival. Also for the treatment of erectile dysfunction due to neurogenic, vasculogenic, psychogenic, or mixed etiology.
DB00905BimatoprostFor the reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication.
DB00917DinoprostoneFor the termination of pregnancy during the second trimester (from the 12th through the 20th gestational week as calculated from the first day of the last normal menstrual period), as well as for evacuation of the uterine contents in the management of missed abortion or intrauterine fetal death up to 28 weeks of gestational age as calculated from the first day of the last normal menstrual period. Also used in the management of nonmetastatic gestational trophoblastic disease (benign hydatidiform mole). Other indications include improving the cervical inducibility (cervical "ripening") in pregnant women at or near term with a medical or obstetrical need for labor induction, and the management of postpartum hemorrhage.
DB00926EtretinateFor the treatment of severe psoriasis in adults.
DB00929MisoprostolIndicated for the treatment of ulceration (duodenal, gastric and NSAID induced) and prophylaxis for NSAID induced ulceration. Misoprostol is also indicated for other uses that are not approved in Canada, including the medical termination of an intrauterine pregnancy used alone or in combination with methotrexate,as well as the induction of labour in a selected population of pregnant women with unfavourable cervices. This indication is avoided in women with prior uterine surgery or cesarean surgery due to an increased risk of possible uterine rupture. Misoprostol is also used for the prevention or treatment of serious postpartum hemorrhage.
DB00982IsotretinoinFor the treatment of severe recalcitrant nodular acne
DB01046LubiprostoneFor the treatment of chronic idiopathic constipation in the adult population. Also used for the treatment of irritable bowel syndrome with constipation in women who are 18 years of age or older.
DB01088IloprostUsed for the treatment of pulmonary arterial hypertension.
DB01160Dinoprost TromethamineUsed for aborting second-trimester pregnancy (between the twelfth to eighteenth week of gestation) and in incomplete abortion or for therapeutic abortion in cases of intrauterine fetal death and congenital abnormalities incompatible with life. Also used at low-doses for medically indicated induction of labor at term. Also injected intra-arterially for use as a vasodilator to assist in angiography.
DB01240EpoprostenolFor the long-term intravenous treatment of primary pulmonary hypertension and pulmonary hypertension associated with the scleroderma spectrum of disease in NYHA Class III and Class IV patients who do not respond adequately to conventional therapy.
DB01276ExenatideIndicated as adjunctive therapy to improve glycemic control in patients with Type 2 diabetes mellitus who are taking metformin, a sulfonylurea, or a combination of both, but have not achieved adequate glycemic control.
DB01277MecaserminFor the long-term treatment of growth failure in pediatric patients with Primary IGFD or with GH gene deletion who have developed neutralizing antibodies to GH. It is not indicated to treat Secondary IGFD resulting from GH deficiency, malnutrition, hypothyroidism or other causes; it is not a substitute for GH therapy.
DB01373CalciumCalcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. It is vital in cell signaling, muscular contractions, bone health, and signalling cascades.
DB014415-Methoxy-N,N-diisopropyltryptamineNot Available
DB01445BufotenineNot Available
DB01839Propylene glycolNot Available
DB01853Bacteriochlorophyll ANot Available
DB01911N-MethylmesoporphyrinNot Available
DB021196-Hydroxymethyl-7,8-DihydropterinNot Available
DB02133Chlorophyll ANot Available
DB02261Platelet Activating FactorNot Available
DB02285ProtoporphyrinNot Available
DB02304Prostaglandin B2Not Available
DB02385D-threo-neopterinNot Available
DB02460Hydrogenobyrinic AcidNot Available
DB02577MesohemeNot Available
DB026994-OxoretinolNot Available
DB02832SirohemeNot Available
DB02877Arotinoid acidNot Available
DB03001PeridininNot Available
DB03147Flavin adenine dinucleotideUsed to treat eye diseases caused by vitamin B2 deficiency, such as keratitis and blepharitis.
DB031976-HydroxymethylpterinNot Available
DB03317Heme CNot Available
DB03404HeminUsed in the management of porphyria attacks, particularly in acute intermittent porphyria.
DB03418DiacetyldeuterohemeNot Available
DB03429CardiolipinNot Available
DB03460ViolaxanthinNot Available
DB03469Heme DNot Available
DB03727Coproporphyrin INot Available
DB03866Prostaglandin G2Not Available
DB03886BiopterinNot Available
DB03913Coenzyme F420Not Available
DB04196Pteroic AcidNot Available
DB043457,8-dimethylalloxazineNot Available
DB04400L-erythro-7,8-dihydrobiopterinNot Available
DB044257,8-DihydroneopterinNot Available
DB04461Coproporphyrinogen IIINot Available
DB04506Chlorophyll BNot Available
DB04557Arachidonic AcidNot Available
DB04622N-ACETYLHISTAMINENot Available
DB047895-methyltetrahydrofolic acidNot Available
DB04803VerdohemeNot Available
DB04912StannsoporfinInvestigated for use/treatment in liver disease, metabolic disease, and pediatric indications.
DB04925DesmoteplaseInvestigated for use/treatment in cerebral ischemia and strokes.
DB04933EritoranInvestigated for use/treatment in sepsis and septicemia.
DB04980LemuteporfinIntended for the treatment of benign prostatic hyperplasia and prostrate disorders.
DB05006AdecatumumabInvestigated for use/treatment in breast cancer and prostate cancer.
DB05076FenretinideInvestigated for use/treatment in macular degeneration.
DB05084AbaloparatideInvestigated for use/treatment in postmenopausal osteoporosis to reduce vertebral and/or non-vertebral fractures.
DB05098LeptinInvestigated for use/treatment in lipodystrophy and obesity.
DB05099AncrodFor the treatment of established deep vein thrombosis; central retinal and branch vein thrombosis; priapism; pulmonary hypertension of embolic origin; embolism after insertion of prosthetic cardiac valves; rethrombosis after thrombolytic therapy and rethrombosis after vascular surgery. It is also indicated for the prevention of deep venous thrombosis after repair of the fractured neck of a femur.
DB05160TopsalysinInvestigated for use/treatment in benign prostatic hyperplasia, cancer/tumors (unspecified), prostate cancer, prostate disorders, and solid tumors.
DB05168VintafolideInvestigated for use/treatment in solid tumors.
DB05229BeraprostFor the treatment of pulmonary hypertension.
DB05232TetrodotoxinFor the treatment of chronic and breakthrough pain in advanced cancer patients as well as for the treatment of opioid dependence.
DB05258Natural alpha interferonInvestigated for use/treatment in hepatitis (viral, C), leukemia (lymphoid), leukemia (myeloid), leukemia (unspecified), and melanoma.
DB05262OxypurinolIntended for the treatment of congestive heart failure and hyperuricemia.
DB05296Motexafin lutetiumInvestigated for use/treatment in brain cancer, breast cancer, cervical dysplasia/cancer, prostate cancer, cancer/tumors (unspecified), coronary artery disease, macular degeneration, and peripheral vascular disease.
DB05299keyhole limpet hemocyaninInvestigated for use/treatment in bladder cancer and solid tumors.
DB05305Cintredekin BesudotoxInvestigated for use/treatment in brain cancer.
DB05332RomiplostimTreatment of chronic immune thrombocytopenic purpura.
DB05344Ciliary neurotrophic factorInvestigated for use/treatment in eye disorders/infections, macular degeneration, and retinal disorders (unspecified).
DB05381HistamineHistamine phosphate is indicated as a diagnostic aid for evaluation of gastric acid secretory function.
DB05396Albinterferon Alfa-2BInvestigated for use/treatment in hepatitis (viral, C).
DB05413TifuvirtideInvestigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.
DB05428motexafin gadoliniumInvestigated for use/treatment in brain cancer, cancer/tumors (unspecified), lung cancer, and lymphoma (non-hodgkin's).
DB05718Maxy-G34Investigated for use/treatment in adverse effects (chemotherapy) and neutropenics.
DB05793PRO-542Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections, HIV infection, and pediatric indications.
DB05874AEOL 10150Investigated for use/treatment in amyotrophic lateral sclerosis (ALS).
DB05875substance PInvestigated for use/treatment in acute respiratory distress syndrome (ARDS) and viral infection.
DB06196IcatibantApproved for use in acute attacks of hereditary angioedema (HAE). Investigated for use/treatment in angioedema, liver disease, and burns and burn infections.
DB06283ZiconotideNot Available
DB06543AstaxanthinInvestigated for use/treatment in eye disorders/infections, cancer/tumors (unspecified), and asthma.
DB06755Beta caroteneNot Available
DB06813PralatrexateTreatment of relapsed or refractory peripheral T-cell lymphoma.
DB06826UnoprostoneFor the lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication.
DB070313-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acidNot Available
DB08455Ro 12-7310Not Available
DB08819TafluprostTafluprost is indicated for reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
DB08878AminopterinPrior to its withdrawal, aminopterin was initially used in the treatment of childhood leukemia; specifically to induce remissions. Later, aminopterin was used off-label in the United States to treat psoriasis, yielding dramatic lesion clearing. Aminopterin was later supplanted by methotrexate for treating cancer because of its better therapeutic index. Aminopterin (as well as methotrexate) has also been explored for use as an abortifacient. However, their association with severe congenital malformations and teratogenic effects have become known as fetal aminopterin syndrome.
DB08887Icosapent ethylIcosapent ethyl is used as adjunct therapy to reduce triglyceride (TG) levels in adults with severe (>500 mg/dL) hypertriglyceridemia.
DB08964GemeprostIndicated for the softening and dilatation of the cervix uteri prior to transcervical, intrauterine operative procedures in the first trimester of pregnancy or facilitating therapeutic termination of pregnancy in patients in the second trimester of gestation.
DB09012CarbazochromeIndicated for capillary and parenchymal hemorrhage (trauma, tonsillectomy, during surgery), intestinal bleeding, and thrombocytopenic purpura.
DB09046MetreleptinMetreleptin is indicated as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy.
DB09103AncestimNot Available
DB09107Methoxy polyethylene glycol-epoetin betaFor the treatment of patients with anaemia associated with chronic kidney disease. Not a substitute for RBC transfusion if immediate correction of anemia is required.
DB09109Turoctocog alfaNot Available
DB09122Peginterferon beta-1aFor the treatment of patients with relapsing forms of multiple sclerosis.
DB09211LimaprostLimaprost is used for the improvement of various ischemic symptoms such as ulcer, pain and feeling of coldness associated with thromboangiitis obliterans as well as improvement of subjective symptoms (pain and numbness of lower legs) and gait ability associated with acquired lumbar spinal canal stenosis (in patients with bilateral intermittent claudication showing normal SLR test result).
DB09222Fibrinogen HumanFor the treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.
DB10789Bordetella pertussis pertactin antigenNot Available
DB11176ZeaxanthinNot Available
DB11231LycopeneNot Available
DB11253Xanthan gumNot Available
DB11300ThrombinNot Available
DB11311ProthrombinFor use in the emergency reversal of coagulation factor deficiency in patients receiving vitamin K antagonist therapy. Prothrombin is administered as part of a cocktail containing several coagulation factors.
DB11312Protein CProtein C Concentrate is indicated for pediatric and adult patients with severe congenital Protein C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans.
DB11330Factor IX Complex (Human)Factor IX Complex is indicated for the prevention and control of hemorrhagic episodes in hemophilia B patients. It is also indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with acute major bleeding or who require rapid reversal of therapy.
DB11596LevoleucovorinLevoleucovorin is indicated for use as rescue therapy following high-dose methotrexate in the treatment of osteosarcoma or for diminishing the toxicity associated with inadvertent overdosage of folic acid antagonists. Levoleucovorin, as the product Fusilev (FDA, dosed at one-half the usual dose of racemic d,l-leucovorin), has an additional indication for use in combination chemotherapy with 5-fluorouracil in the palliative treatment of patients with advanced metastatic colorectal cancer (although they should not be mixed in the same infusion as a precipitate may form).
DB11598Antithrombin III humanAntithrombin III human is a human antithrombin (AT) indicated in patients with hereditary antithrombin deficiency for the treatment and prevention of thromboembolism and prevention of peri-operative and peri-partum thromboembolism
DB11601Tuberculin Purified Protein DerivativeIndicated as a diagnostic agent in Mantoux Test used to detect infection with *Mycobacterium tuberculosis*.
DB11630TemoporfinNot Available
DB11660Latanoprostene BunodLatanoprost bunod opthalmic solution is indicated for the reduction of intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
DB11668Rusalatide acetateNot Available
DB11724BombesinNot Available
DB11777CenderitideNot Available
DB11812TalaporfinNot Available
DB11831DinitrochlorobenzeneNot Available
DB11842Angiotensin IiNot Available
DB11858Leukotriene D4Not Available
DB11874CrocinNot Available
DB11890CilengitideNot Available
DB11955AvoterminNot Available
DB11975TAK-448Not Available
DB11997Interleukin-7Not Available
DB12075NagrestipenNot Available
DB12112Zuretinol acetateNot Available
DB12126BradykininNot Available
DB12182BinetrakinNot Available
DB12266EpofolateNot Available
DB12349DulanerminNot Available
DB12409Vatreptacog alfaNot Available
DB12431MuplestimNot Available
DB12458MuscimolNot Available
DB12525MolgramostimNot Available
DB12575RonopterinNot Available
DB12616SpriferminNot Available
DB12620Nerve Growth FactorNot Available
DB12652Endothelin-1Not Available
DB12684AviscumineNot Available
DB12688Moxetumomab PasudotoxNot Available
DB12699BalugrastimNot Available
DB12708SulprostoneNot Available
DB12726MonteplaseNot Available
DB12769LometrexolNot Available
DB12789DinoprostNot Available
DB12807Naptumomab EstafenatoxNot Available
DB12880Interleukin-10Not Available
DB12909Factor XIII (human)Not Available
DB12961Leukotriene B4Not Available
DB12989NeosaxitoxinNot Available
DB13105Resolvin E1Not Available
DB13133Von Willebrand Factor HumanNot Available
DB13144LenograstimThe drug is used to reduce the risk of life-threatening infection in patients with neutropenia, particularly after cytotoxic chemotherapy. Lenograstim is indicated as a treatment to reduce the duration of neutropenia and the severity of infections in patients with non-myeloid malignancy who have undergone autologous or allogeneic bone marrow transplantation, or treatment with established cytotoxic chemotherapy and in addition to reduce the incidence of infection associated with established cytotoxic chemotherapy. Lenograstim is also indicated to mobilise peripheral blood progenitor cells (PBPCs) with Lenograstim alone, or after myelosuppressive chemotherapy, in order to accelerate haematopoietic recovery by infusion of such cells, after myelosuppressive or myeloablative therapy. Lenograstim is also indicated to accelerate the engraftment of these cells after their reinfusion. GRANOCYTE is also indicated for the treatment of severe chronic neutropenia including congenital agranulocytosis (Kostmann's syndrome).
DB13148Coagulation factor X humanCoagulation Factor X (Human), is a plasma-derived human blood coagulation factor is indicated for subjects with hereditary Factor X deficiency for: •On-demand treatment and control of bleeding episodes •Perioperative management of bleeding in patients with mild hereditary Factor X deficiency
DB13149Protein S humanFor use in the emergency reversal of coagulation factor deficiency in patients recieving vitamin K antagonist therapy [FDA Label]. Protein S is administered as part of a cocktail containing several other coagulation factors.
DB13150Coagulation factor VII humanMay be administered in cases of uncontrolled bleeding. Factor VII alone can be used in the treatment of congenital hemophilia A or B, acquired hemophilia, congenital factor VII deficiency, and Glanzmann's thrombasthenia. Off label use in the treatment of refractory bleeding after cardiac surgery and warfarin related intracerebral hemorrhage. Brands for human factor VII are currently only in combination with other vitamin K coagulation factors and can be used to reverse vitamin K antagonist activity in patients with acute major bleeds or for urgent surgery/invasive procedures.
DB13192Antihemophilic factor humanThe human antihemophilic factor is indicated for the cases of hemophilia A, also known as classical hemophilia for the prevention and control of hemorrhagic episodes.[L1055] If surgery is needed in patients with hemophilia A there is a need of correction of the clotting abnormality. In this cases, the human antihemophilic factor may be administered followed by intermittent maintenance doses.[L1053] The hemophilia A is characterized by the deficiency of the coagulation factor VIII that results in prolonged blood flow after injury or surgery as well as recurrent bleeding.[T56]
DB13889Meningococcal group A polysaccharideNot Available
DB13890Meningococcal group C polysaccharideNot Available
DrugDrug NameTargetType
DB00004Denileukin diftitoxInterleukin-2 receptor subunit alphatarget
DB00004Denileukin diftitoxCytokine receptor common subunit gammatarget
DB00004Denileukin diftitoxInterleukin-2 receptor subunit betatarget
DB00005EtanerceptTumor necrosis factortarget
DB00005EtanerceptLymphotoxin-alphatarget
DB00005EtanerceptLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00005EtanerceptComplement C1r subcomponenttarget
DB00005EtanerceptComplement C1q subcomponent subunit Atarget
DB00005EtanerceptComplement C1q subcomponent subunit Btarget
DB00005EtanerceptComplement C1q subcomponent subunit Ctarget
DB00005EtanerceptLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00005EtanerceptComplement C1s subcomponenttarget
DB00005EtanerceptHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00005EtanerceptLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00005EtanerceptLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00005EtanerceptLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00005EtanerceptTumor necrosis factor receptor superfamily member 1Btarget
DB00005EtanerceptProstaglandin G/H synthase 2enzyme
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 2target
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 1target
DB00008Peginterferon alfa-2aCytochrome P450 1A2enzyme
DB00009AlteplaseUrokinase plasminogen activator surface receptortarget
DB00009AlteplaseFibrinogen alpha chaintarget
DB00009AlteplasePlasminogentarget
DB00009AlteplasePlasminogen activator inhibitor 1target
DB00011Interferon alfa-n1Interferon alpha/beta receptor 2target
DB00011Interferon alfa-n1Interferon alpha/beta receptor 1target
DB00012Darbepoetin alfaErythropoietin receptortarget
DB00013UrokinaseUrokinase plasminogen activator surface receptortarget
DB00013UrokinasePlasminogentarget
DB00013UrokinaseUrokinase-type plasminogen activatortarget
DB00013UrokinaseTissue-type plasminogen activatortarget
DB00013UrokinasePlasminogen activator inhibitor 2target
DB00013UrokinasePlasminogen activator inhibitor 1target
DB00013UrokinasePlasma serine protease inhibitortarget
DB00013UrokinaseNidogen-1target
DB00013UrokinaseLow-density lipoprotein receptor-related protein 2target
DB00013UrokinaseSuppressor of tumorigenicity 14 proteintarget
DB00015ReteplaseUrokinase plasminogen activator surface receptortarget
DB00015ReteplaseFibrinogen alpha chaintarget
DB00015ReteplasePlasminogentarget
DB00015ReteplasePlasminogen activator inhibitor 1target
DB00016ErythropoietinErythropoietin receptortarget
DB00018Interferon alfa-n3Interferon alpha/beta receptor 1target
DB00018Interferon alfa-n3Interferon alpha/beta receptor 2target
DB00019PegfilgrastimGranulocyte colony-stimulating factor receptortarget
DB00019PegfilgrastimNeutrophil elastasetarget
DB00020SargramostimGranulocyte-macrophage colony-stimulating factor receptor subunit alphatarget
DB00020SargramostimBone marrow proteoglycantarget
DB00020SargramostimInterleukin-3 receptor subunit alphatarget
DB00020SargramostimCytokine receptor common subunit betatarget
DB00020SargramostimSyndecan-2target
DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 1target
DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 2target
DB00022Peginterferon alfa-2bCytochrome P450 1A2enzyme
DB00022Peginterferon alfa-2bCytochrome P450 2D6enzyme
DB00025Antihemophilic factor, human recombinantCoagulation factor Xtarget
DB00025Antihemophilic factor, human recombinantPhytanoyl-CoA dioxygenase, peroxisomaltarget
DB00025Antihemophilic factor, human recombinantCoagulation factor IXtarget
DB00025Antihemophilic factor, human recombinantAsialoglycoprotein receptor 2target
DB00025Antihemophilic factor, human recombinant78 kDa glucose-regulated proteintarget
DB00025Antihemophilic factor, human recombinantCalreticulintarget
DB00025Antihemophilic factor, human recombinantCalnexintarget
DB00025Antihemophilic factor, human recombinantProtein ERGIC-53target
DB00025Antihemophilic factor, human recombinantProlow-density lipoprotein receptor-related protein 1target
DB00025Antihemophilic factor, human recombinantMultiple coagulation factor deficiency protein 2target
DB00025Antihemophilic factor, human recombinantvon Willebrand factortarget
DB00025Antihemophilic factor, human recombinantProthrombinenzyme
DB00025Antihemophilic factor, human recombinantVitamin K-dependent protein Cenzyme
DB00026AnakinraInterleukin-1 receptor type 1target
DB00029AnistreplaseUrokinase plasminogen activator surface receptortarget
DB00029AnistreplaseFibrinogen alpha chaintarget
DB00029AnistreplasePlasminogentarget
DB00029AnistreplasePlasminogen activator inhibitor 1target
DB00031TenecteplaseUrokinase plasminogen activator surface receptortarget
DB00031TenecteplasePlasminogen activator inhibitor 1target
DB00031TenecteplaseFibrinogen alpha chaintarget
DB00031TenecteplasePlasminogen activator inhibitor 2target
DB00031TenecteplaseTetranectintarget
DB00031TenecteplaseKeratin, type II cytoskeletal 8target
DB00031TenecteplaseAnnexin A2target
DB00031TenecteplaseCalreticulintarget
DB00031TenecteplaseCalnexintarget
DB00031TenecteplaseProlow-density lipoprotein receptor-related protein 1target
DB00031TenecteplasePlasminogentarget
DB00033Interferon gamma-1bInterferon gamma receptor 1target
DB00033Interferon gamma-1bInterferon gamma receptor 2target
DB00033Interferon gamma-1bCytochrome P450 1A2enzyme
DB00034Interferon Alfa-2a, RecombinantInterferon alpha/beta receptor 1target
DB00034Interferon Alfa-2a, RecombinantInterferon alpha/beta receptor 2target
DB00036Coagulation factor VIIa Recombinant HumanCoagulation factor Xtarget
DB00036Coagulation factor VIIa Recombinant HumanTissue factortarget
DB00036Coagulation factor VIIa Recombinant HumanSerine protease hepsintarget
DB00036Coagulation factor VIIa Recombinant HumanTissue factor pathway inhibitortarget
DB00036Coagulation factor VIIa Recombinant HumanVitamin K-dependent gamma-carboxylasetarget
DB00036Coagulation factor VIIa Recombinant HumanCoagulation factor VIItarget
DB00038OprelvekinInterleukin-11 receptor subunit alphatarget
DB00039PaliferminFibroblast growth factor receptor 2target
DB00039PaliferminNeuropilin-1target
DB00039PaliferminFibroblast growth factor receptor 1target
DB00039PaliferminFibroblast growth factor receptor 4target
DB00039PaliferminFibroblast growth factor receptor 3target
DB00039PaliferminBasement membrane-specific heparan sulfate proteoglycan core proteintarget
DB00041AldesleukinInterleukin-2 receptor subunit betatarget
DB00041AldesleukinInterleukin-2 receptor subunit alphatarget
DB00041AldesleukinCytokine receptor common subunit gammatarget
DB00041AldesleukinProstaglandin G/H synthase 2enzyme
DB00041AldesleukinCytosolic phospholipase A2enzyme
DB00041AldesleukinCytochrome P450 3A4enzyme
DB00041AldesleukinXanthine dehydrogenase/oxidaseenzyme
DB00041AldesleukinCytochrome P450 2E1enzyme
DB00042Botulinum Toxin Type BVesicle-associated membrane protein 1target
DB00042Botulinum Toxin Type BVesicle-associated membrane protein 2target
DB00042Botulinum Toxin Type BSynaptotagmin-2target
DB00055Drotrecogin alfaCoagulation factor VIIItarget
DB00055Drotrecogin alfaCoagulation factor Vtarget
DB00055Drotrecogin alfaPlasminogen activator inhibitor 1target
DB00055Drotrecogin alfaThrombomodulintarget
DB00055Drotrecogin alfaVitamin K-dependent protein Starget
DB00055Drotrecogin alfaCeruloplasmintarget
DB00055Drotrecogin alfaProthrombintarget
DB00055Drotrecogin alfaPlatelet factor 4target
DB00055Drotrecogin alfaPlasma serine protease inhibitortarget
DB00055Drotrecogin alfaSerpin B6target
DB00055Drotrecogin alfaVitamin K-dependent gamma-carboxylasetarget
DB00055Drotrecogin alfaEndothelial protein C receptortarget
DB00060Interferon beta-1aInterferon alpha/beta receptor 1target
DB00060Interferon beta-1aInterferon alpha/beta receptor 2target
DB00068Interferon beta-1bInterferon alpha/beta receptor 1target
DB00068Interferon beta-1bInterferon alpha/beta receptor 2target
DB00069Interferon alfacon-1Interferon alpha/beta receptor 1target
DB00069Interferon alfacon-1Interferon alpha/beta receptor 2target
DB00070HyaluronidaseTransforming growth factor beta-1target
DB00070HyaluronidaseSerum albumincarrier
DB00070HyaluronidaseHyaluronantarget
DB00083Botulinum Toxin Type ASynaptosomal-associated protein 25target
DB00083Botulinum Toxin Type ARho-related GTP-binding protein RhoBtarget
DB00086StreptokinasePlasminogentarget
DB00086StreptokinaseProteinase-activated receptor 1target
DB00086StreptokinaseCytosolic phospholipase A2enzyme
DB00099FilgrastimGranulocyte colony-stimulating factor receptortarget
DB00099FilgrastimNeutrophil elastasetarget
DB00102BecaplerminPlatelet-derived growth factor receptor betatarget
DB00102BecaplerminAlpha-2-macroglobulintarget
DB00102BecaplerminPlatelet-derived growth factor receptor alphatarget
DB00105Interferon Alfa-2b, RecombinantInterferon alpha/beta receptor 2target
DB00105Interferon Alfa-2b, RecombinantInterferon alpha/beta receptor 1target
DB00105Interferon Alfa-2b, RecombinantCytochrome P450 1A2enzyme
DB00109EnfuvirtideEnvelope glycoproteintarget
DB00109EnfuvirtideCytochrome P450 2C19enzyme
DB00109EnfuvirtideCytochrome P450 2E1enzyme
DB00116Tetrahydrofolic acidC-1-tetrahydrofolate synthase, cytoplasmictarget
DB00116Tetrahydrofolic acidBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrialtarget
DB00116Tetrahydrofolic acidAminomethyltransferase, mitochondrialtarget
DB00116Tetrahydrofolic acidCytosolic 10-formyltetrahydrofolate dehydrogenasetarget
DB00116Tetrahydrofolic acidMethionine synthasetarget
DB00116Tetrahydrofolic acidFormimidoyltransferase-cyclodeaminasetarget
DB00116Tetrahydrofolic acidBifunctional purine biosynthesis protein PURHtarget
DB00116Tetrahydrofolic acidSerine hydroxymethyltransferase, cytosolictarget
DB00116Tetrahydrofolic acidSerine hydroxymethyltransferase, mitochondrialtarget
DB00116Tetrahydrofolic acidMethylenetetrahydrofolate reductasetarget
DB00116Tetrahydrofolic acidSerine hydroxymethyltransferasetarget
DB00116Tetrahydrofolic acidMethionyl-tRNA formyltransferase, mitochondrialtarget
DB00116Tetrahydrofolic acidCanalicular multispecific organic anion transporter 1transporter
DB00140RiboflavinFlavin reductase (NADPH)target
DB00140RiboflavinRiboflavin kinasetarget
DB00140RiboflavinRiboflavin synthasetarget
DB00140RiboflavinAmine oxidase [flavin-containing] Aenzyme
DB00140RiboflavinMethylenetetrahydrofolate reductaseenzyme
DB00140RiboflavinSolute carrier family 22 member 6transporter
DB00154Dihomo-gamma-linolenic acidProstaglandin G/H synthase 2target
DB00154Dihomo-gamma-linolenic acidProstaglandin G/H synthase 1target
DB00154Dihomo-gamma-linolenic acidFatty acid-binding protein, braincarrier
DB00158Folic AcidFolate receptor gammatarget
DB00158Folic AcidFolate receptor betatarget
DB00158Folic AcidMethylenetetrahydrofolate reductaseenzyme
DB00158Folic AcidMultidrug resistance-associated protein 4transporter
DB00158Folic AcidSolute carrier family 22 member 6transporter
DB00158Folic AcidCanalicular multispecific organic anion transporter 2transporter
DB00158Folic AcidATP-binding cassette sub-family C member 11transporter
DB00158Folic AcidATP-binding cassette sub-family G member 2transporter
DB00158Folic AcidCytochrome P450 2E1enzyme
DB00158Folic AcidProton-coupled folate transportertransporter
DB00158Folic AcidMitochondrial folate transporter/carriertransporter
DB00158Folic AcidGamma-glutamyl hydrolaseenzyme
DB00158Folic AcidSerum albumincarrier
DB00158Folic AcidFolate receptor alphatarget
DB00159IcosapentProstaglandin G/H synthase 2target
DB00159IcosapentProstaglandin G/H synthase 1target
DB00159IcosapentFree fatty acid receptor 1target
DB00159IcosapentFatty acid-binding protein, braincarrier
DB00159IcosapentFatty acid desaturase 1target
DB00159IcosapentLong-chain-fatty-acid--CoA ligase 4target
DB00159IcosapentLong-chain-fatty-acid--CoA ligase 3target
DB00159IcosapentSodium/calcium exchanger 1target
DB00159IcosapentPeroxisome proliferator-activated receptor gammatarget
DB00159IcosapentPeroxisome proliferator-activated receptor deltatarget
DB00159IcosapentTransient receptor potential cation channel subfamily V member 1target
DB00159IcosapentPeroxisome proliferator-activated receptor alphatarget
DB00159IcosapentSerum albumincarrier
DB00162Vitamin ARetinol dehydrogenase 12target
DB00162Vitamin ARetinol-binding protein 1target
DB00162Vitamin A11-cis retinol dehydrogenasetarget
DB00162Vitamin ARetinol dehydrogenase 13target
DB00162Vitamin ARetinol-binding protein 3target
DB00162Vitamin ARetinol-binding protein 5carrier
DB00162Vitamin ARetinoid-binding protein 7carrier
DB00162Vitamin ARetinol-binding protein 4carrier
DB00162Vitamin ARetinol-binding protein 2carrier
DB00162Vitamin ARetinal dehydrogenase 2target
DB00162Vitamin ARetinal dehydrogenase 1target
DB00162Vitamin ARetinaldehyde-binding protein 1target
DB00162Vitamin ALecithin retinol acyltransferasetarget
DB00162Vitamin AShort-chain dehydrogenase/reductase 3target
DB00162Vitamin AAldehyde dehydrogenase family 1 member A3target
DB00162Vitamin AAll-trans-retinol 13,14-reductasetarget
DB00162Vitamin ARetinol dehydrogenase 11target
DB00162Vitamin ADehydrogenase/reductase SDR family member 4target
DB00162Vitamin ARetinol dehydrogenase 14target
DB00162Vitamin ARetinol dehydrogenase 8target
DB00162Vitamin ACytochrome P450 1A1enzyme
DB00162Vitamin ACytochrome P450 26A1enzyme
DB00162Vitamin AApolipoprotein Dtarget
DB00162Vitamin AHematopoietic prostaglandin D synthasetarget
DB00162Vitamin ASerum albumincarrier
DB00287TravoprostProstaglandin F2-alpha receptortarget
DB00360SapropterinPhenylalanine-4-hydroxylasetarget
DB00360SapropterinNitric oxide synthase, endothelialtarget
DB00360SapropterinTyrosine 3-monooxygenasetarget
DB00360SapropterinTryptophan 5-hydroxylase 1target
DB00360SapropterinProstaglandin G/H synthase 2enzyme
DB00374TreprostinilP2Y purinoceptor 12target
DB00374TreprostinilPeroxisome proliferator-activated receptor deltatarget
DB00374TreprostinilProstacyclin receptortarget
DB00374TreprostinilCytochrome P450 2C9enzyme
DB00429Carboprost TromethamineProstaglandin E2 receptor EP1 subtypetarget
DB00459AcitretinRetinoic acid receptor alphatarget
DB00459AcitretinRetinoic acid receptor RXR-betatarget
DB00459AcitretinRetinoic acid receptor gammatarget
DB00459AcitretinRetinoic acid receptor betatarget
DB00459AcitretinRetinoic acid receptor RXR-gammatarget
DB00459AcitretinRetinoic acid receptor RXR-alphatarget
DB00459AcitretinSerum albumincarrier
DB00459AcitretinRetinol-binding protein 1target
DB00459AcitretinCytochrome P450 26A1enzyme
DB00523AlitretinoinRetinoic acid receptor alphatarget
DB00523AlitretinoinRetinoic acid receptor RXR-betatarget
DB00523AlitretinoinRetinoic acid receptor gammatarget
DB00523AlitretinoinRetinoic acid receptor betatarget
DB00523AlitretinoinRetinoic acid receptor RXR-gammatarget
DB00523AlitretinoinRetinoic acid receptor RXR-alphatarget
DB00523AlitretinoinCellular retinoic acid-binding protein 2carrier
DB00523AlitretinoinCellular retinoic acid-binding protein 1carrier
DB00523AlitretinoinMultidrug resistance protein 1transporter
DB00523AlitretinoinCytochrome P450 1A2enzyme
DB00523AlitretinoinInsulin-like growth factor-binding protein 3target
DB00523AlitretinoinPregnancy-specific beta-1-glycoprotein 5target
DB00523AlitretinoinCytochrome P450 26C1target
DB00553MethoxsalenDNAtarget
DB00553MethoxsalenCytochrome P450 2A6enzyme
DB00553MethoxsalenCytochrome P450 1A2enzyme
DB00553MethoxsalenCytochrome P450 1A1enzyme
DB00553MethoxsalenCytochrome P450 2A13enzyme
DB00553MethoxsalenCytochrome P450 3A4enzyme
DB00553MethoxsalenCytochrome P450 2D6enzyme
DB00563MethotrexateDihydrofolate reductasetarget
DB00563MethotrexateAldehyde oxidaseenzyme
DB00563MethotrexateMethylenetetrahydrofolate reductaseenzyme
DB00563MethotrexateSerum albumincarrier
DB00563MethotrexateCanalicular multispecific organic anion transporter 2transporter
DB00563MethotrexateMultidrug resistance-associated protein 4transporter
DB00563MethotrexateMultidrug resistance-associated protein 1transporter
DB00563MethotrexateSolute carrier family 22 member 6transporter
DB00563MethotrexateMultidrug resistance-associated protein 7transporter
DB00563MethotrexateSolute carrier family 22 member 8transporter
DB00563MethotrexateCanalicular multispecific organic anion transporter 1transporter
DB00563MethotrexateMultidrug resistance protein 1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1A2transporter
DB00563MethotrexateMonocarboxylate transporter 1transporter
DB00563MethotrexateATP-binding cassette sub-family C member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B3transporter
DB00563MethotrexateSolute carrier family 22 member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1C1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 3A1transporter
DB00563MethotrexateATP-binding cassette sub-family G member 2transporter
DB00563MethotrexateSolute carrier family 22 member 7transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B1transporter
DB00563Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00563MethotrexateProton-coupled folate transportertransporter
DB00563MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
DB00563MethotrexateGamma-glutamyl hydrolaseenzyme
DB00563MethotrexateDihydrofolate reductaseenzyme
DB00563MethotrexateThymidylate synthaseenzyme
DB00563MethotrexateBifunctional purine biosynthesis protein PURHenzyme
DB00563MethotrexateSolute carrier organic anion transporter family member 4C1transporter
DB00563MethotrexateFolate transporter 1transporter
DB00563MethotrexateFolate receptor alphatransporter
DB00640AdenosineAdenosine receptor A3target
DB00640AdenosineAdenosine deaminaseenzyme
DB00640AdenosineAdenosine kinaseenzyme
DB00640AdenosineAdenosine receptor A1target
DB00640AdenosineAdenosine receptor A2atarget
DB00640AdenosineAdenosine receptor A2btarget
DB00640AdenosineSolute carrier family 28 member 3transporter
DB00654LatanoprostProstaglandin F2-alpha receptortarget
DB00654LatanoprostSolute carrier organic anion transporter family member 2B1transporter
DB00654LatanoprostSolute carrier family 22 member 1transporter
DB00707Porfimer sodiumLow-density lipoprotein receptortarget
DB00707Porfimer sodiumHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00755TretinoinRetinoic acid receptor gammatarget
DB00755TretinoinRetinoic acid receptor RXR-betatarget
DB00755TretinoinRetinal dehydrogenase 1target
DB00755TretinoinRetinoic acid-induced protein 3target
DB00755TretinoinRetinoic acid receptor RXR-gammatarget
DB00755TretinoinNuclear receptor subfamily 0 group B member 1target
DB00755TretinoinRetinal dehydrogenase 2target
DB00755TretinoinRetinoic acid receptor responder protein 1target
DB00755TretinoinCytochrome P450 2C8enzyme
DB00755TretinoinCellular retinoic acid-binding protein 1transporter
DB00755TretinoinCellular retinoic acid-binding protein 2transporter
DB00755TretinoinCytochrome P450 2B6enzyme
DB00755TretinoinCytochrome P450 3A4enzyme
DB00755TretinoinCytochrome P450 3A5enzyme
DB00755TretinoinCytochrome P450 2A6enzyme
DB00755TretinoinCytochrome P450 3A7enzyme
DB00755TretinoinCytochrome P450 2C18enzyme
DB00755TretinoinCytochrome P450 2C9enzyme
DB00755TretinoinCytochrome P450 4A11enzyme
DB00755TretinoinCytochrome P450 1A1enzyme
DB00755TretinoinRetinoic acid receptor alphatarget
DB00755TretinoinRetinoic acid receptor betatarget
DB00755TretinoinLipocalin-1target
DB00755TretinoinOdorant-binding protein 2atarget
DB00755TretinoinRetinol-binding protein 4target
DB00755TretinoinSerum albumincarrier
DB00755Tretinoin[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrialtarget
DB00755TretinoinRetinoic acid receptor RXR-alphatarget
DB00755TretinoinCytochrome P450 26A1target
DB00755TretinoinCytochrome P450 26B1target
DB00755TretinoinCytochrome P450 26C1target
DB00755TretinoinHematopoietic prostaglandin D synthasetarget
DB00770AlprostadilProstaglandin E2 receptor EP2 subtypetarget
DB00770AlprostadilProstaglandin E2 receptor EP1 subtypetarget
DB00770AlprostadilMultidrug resistance-associated protein 5transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 2B1transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 3A1transporter
DB00770AlprostadilMultidrug resistance-associated protein 4transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 2A1transporter
DB00770AlprostadilProstaglandin D2 receptor 2target
DB00905BimatoprostProstaglandin F2-alpha receptortarget
DB00905BimatoprostProstaglandin E2 receptor EP1 subtypetarget
DB00905BimatoprostProstaglandin E2 receptor EP3 subtypetarget
DB00905BimatoprostAldo-keto reductase family 1 member C3target
DB00917DinoprostoneProstaglandin E2 receptor EP2 subtypetarget
DB00917DinoprostoneProstaglandin E2 receptor EP1 subtypetarget
DB00917DinoprostoneProstaglandin E2 receptor EP4 subtypetarget
DB00917DinoprostoneProstaglandin E2 receptor EP3 subtypetarget
DB00917DinoprostoneSolute carrier family 22 member 2transporter
DB00917DinoprostoneSolute carrier family 22 member 1transporter
DB00917DinoprostoneMultidrug resistance-associated protein 5transporter
DB00917DinoprostoneSolute carrier family 22 member 6transporter
DB00917DinoprostoneSolute carrier family 22 member 8transporter
DB00917DinoprostoneSolute carrier family 22 member 11transporter
DB00917DinoprostoneSolute carrier family 22 member 7transporter
DB00917DinoprostoneMultidrug resistance-associated protein 4transporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 2B1transporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 1A2transporter
DB00917DinoprostoneOrganic solute transporter subunit alphatransporter
DB00917DinoprostoneOrganic solute transporter subunit betatransporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 2A1transporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 4A1transporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 1C1transporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 3A1transporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 1B1transporter
DB00917DinoprostoneCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00917DinoprostoneCytochrome P450 19A1enzyme
DB00917DinoprostoneCytochrome P450 1A2enzyme
DB00917DinoprostoneProstaglandin D2 receptor 2target
DB00926EtretinateRetinoic acid receptor alphatarget
DB00926EtretinateRetinoic acid receptor RXR-betatarget
DB00926EtretinateRetinoic acid receptor gammatarget
DB00926EtretinateRetinoic acid receptor betatarget
DB00926EtretinateRetinoic acid receptor RXR-gammatarget
DB00926EtretinateRetinoic acid receptor RXR-alphatarget
DB00926EtretinateCellular retinoic acid-binding protein 1carrier
DB00926EtretinateCytochrome P450 19A1enzyme
DB00926EtretinateCytochrome P450 26A1enzyme
DB00929MisoprostolProstaglandin E2 receptor EP2 subtypetarget
DB00929MisoprostolProstaglandin E2 receptor EP3 subtypetarget
DB00929MisoprostolProstaglandin E2 receptor EP4 subtypetarget
DB00982IsotretinoinRetinoic acid receptor alphatarget
DB01046LubiprostoneChloride channel protein 2target
DB01046LubiprostoneCarbonyl reductase [NADPH] 1enzyme
DB01088IloprostProstacyclin receptortarget
DB01088IloprostTissue-type plasminogen activatortarget
DB01088IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB01088IloprostSolute carrier organic anion transporter family member 2B1transporter
DB01088IloprostSolute carrier organic anion transporter family member 2A1transporter
DB01088IloprostSolute carrier organic anion transporter family member 3A1transporter
DB01088IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01088IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB01088IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB01088IloprostProstaglandin E2 receptor EP1 subtypetarget
DB01088IloprostProstaglandin D2 receptor 2target
DB01160Dinoprost TromethamineProstacyclin receptortarget
DB01160Dinoprost TromethamineProstaglandin F2-alpha receptortarget
DB01160Dinoprost TromethamineSolute carrier family 22 member 2transporter
DB01160Dinoprost TromethamineSolute carrier family 22 member 6transporter
DB01160Dinoprost TromethamineSolute carrier family 22 member 7transporter
DB01160Dinoprost TromethamineSolute carrier family 22 member 8transporter
DB01160Dinoprost TromethamineSolute carrier family 22 member 11transporter
DB01160Dinoprost TromethamineSolute carrier organic anion transporter family member 2A1transporter
DB01160Dinoprost TromethamineSolute carrier organic anion transporter family member 3A1transporter
DB01240EpoprostenolP2Y purinoceptor 12target
DB01240EpoprostenolProstacyclin receptortarget
DB01240EpoprostenolProstacyclin synthasetarget
DB01240EpoprostenolCytochrome P450 2C9enzyme
DB01276ExenatideGlucagon-like peptide 1 receptortarget
DB01276ExenatideSerum albumincarrier
DB01277MecaserminInsulin-like growth factor 1 receptortarget
DB01277MecaserminInsulin-like growth factor-binding protein 3target
DB01277MecaserminInsulin receptortarget
DB01277MecaserminCation-independent mannose-6-phosphate receptortarget
DB01373CalciumProtein S100-Btarget
DB01373CalciumCalpastatintarget
DB01373CalciumCartilage oligomeric matrix proteintarget
DB01373CalciumCalmodulintarget
DB01373CalciumSpectrin beta chain, non-erythrocytic 1target
DB01373CalciumVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01373CalciumTroponin C, skeletal muscletarget
DB01373CalciumTroponin C, slow skeletal and cardiac musclestarget
DB01373CalciumCalcium-transporting ATPase type 2C member 1target
DB01373CalciumAmiloride-sensitive amine oxidase [copper-containing]target
DB01373CalciumProtein S100-A13target
DB01373CalciumAlkaline phosphatase, placental typetarget
DB01373CalciumProtein S100-A8target
DB01373CalciumProtein S100-A9target
DB01373CalciumProtein S100-A2target
DB01373CalciumCeruloplasmintarget
DB01373CalciumBone morphogenetic protein 4target
DB01373CalciumMatrix Gla proteintarget
DB01373CalciumProtocadherin-19target
DB01373CalciumProgrammed cell death protein 6target
DB01445BufotenineAmine oxidase [flavin-containing] Aenzyme
DB01445BufotenineAmine oxidase [flavin-containing] Benzyme
DB01839Propylene glycolCoagulation factor XIII A chaintarget
DB01839Propylene glycolHaloalkane dehalogenasetarget
DB01839Propylene glycolClavaminate synthase 1target
DB01839Propylene glycolLactaldehyde reductasetarget
DB01839Propylene glycolB12-independent glycerol dehydratasetarget
DB01853Bacteriochlorophyll ABacteriochlorophyll a proteintarget
DB01853Bacteriochlorophyll ABacteriochlorophyll a proteintarget
DB01911N-MethylmesoporphyrinFerrochelatasetarget
DB021196-Hydroxymethyl-7,8-Dihydropterin2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinasetarget
DB021196-Hydroxymethyl-7,8-DihydropterinDihydroneopterin aldolasetarget
DB02133Chlorophyll ABeta-lactamase 2target
DB02261Platelet Activating FactorGanglioside GM2 activatortarget
DB02261Platelet Activating FactorMultidrug resistance protein 1transporter
DB02261Platelet Activating FactorPlatelet-activating factor receptortarget
DB02285ProtoporphyrinFerritin light chaintarget
DB02460Hydrogenobyrinic AcidPrecorrin-8X methylmutasetarget
DB02832SirohemeSulfite reductase [NADPH] hemoprotein beta-componenttarget
DB02877Arotinoid acidRetinoic acid receptor betatarget
DB03147Flavin adenine dinucleotidep-hydroxybenzoate hydroxylasetarget
DB03147Flavin adenine dinucleotideNitric oxide synthase, braintarget
DB03147Flavin adenine dinucleotideNAD(P)H dehydrogenase [quinone] 1target
DB03147Flavin adenine dinucleotidep-hydroxybenzoate hydroxylasetarget
DB03147Flavin adenine dinucleotideFumarate reductase flavoprotein subunittarget
DB03147Flavin adenine dinucleotideERO1-like protein betatarget
DB03147Flavin adenine dinucleotideGlutathione reductase, mitochondrialtarget
DB03147Flavin adenine dinucleotideNADPH-ferredoxin reductase FprAtarget
DB03147Flavin adenine dinucleotideNADH-cytochrome b5 reductase 3target
DB03147Flavin adenine dinucleotideCholesterol oxidasetarget
DB03147Flavin adenine dinucleotideThymidylate synthase ThyXtarget
DB03147Flavin adenine dinucleotidePyruvate oxidasetarget
DB03147Flavin adenine dinucleotideGlutathione reductasetarget
DB03147Flavin adenine dinucleotideMonomeric sarcosine oxidasetarget
DB03147Flavin adenine dinucleotideTrypanothione reductasetarget
DB03147Flavin adenine dinucleotideRibosyldihydronicotinamide dehydrogenase [quinone]target
DB03147Flavin adenine dinucleotideIsovaleryl-CoA dehydrogenase, mitochondrialtarget
DB03147Flavin adenine dinucleotideXanthine dehydrogenase/oxidasetarget
DB03147Flavin adenine dinucleotideCholesterol oxidasetarget
DB03147Flavin adenine dinucleotideDihydropyrimidine dehydrogenase [NADP(+)]target
DB03147Flavin adenine dinucleotideD-lactate dehydrogenasetarget
DB03147Flavin adenine dinucleotideThioredoxin reductase 1, cytoplasmictarget
DB03147Flavin adenine dinucleotideIsobutyryl-CoA dehydrogenase, mitochondrialtarget
DB03147Flavin adenine dinucleotideApoptosis-inducing factor 1, mitochondrialtarget
DB03147Flavin adenine dinucleotideUDP-galactopyranose mutasetarget
DB03147Flavin adenine dinucleotideFlavohemoproteintarget
DB03147Flavin adenine dinucleotideGlycine oxidasetarget
DB03147Flavin adenine dinucleotideNADPH--cytochrome P450 reductasetarget
DB03147Flavin adenine dinucleotideGlutaryl-CoA dehydrogenase, mitochondrialtarget
DB03147Flavin adenine dinucleotideMedium-chain specific acyl-CoA dehydrogenase, mitochondrialtarget
DB03147Flavin adenine dinucleotideD-amino-acid oxidasetarget
DB03147Flavin adenine dinucleotideBifunctional protein PutAtarget
DB03147Flavin adenine dinucleotideDeoxyribodipyrimidine photo-lyasetarget
DB03147Flavin adenine dinucleotideAmine oxidase [flavin-containing] Atarget
DB03147Flavin adenine dinucleotideShort-chain specific acyl-CoA dehydrogenase, mitochondrialtarget
DB03147Flavin adenine dinucleotideL-amino-acid oxidasetarget
DB03147Flavin adenine dinucleotide2,4-dienoyl-CoA reductase [NADPH]target
DB03147Flavin adenine dinucleotide2-oxopropyl-CoM reductase, carboxylatingtarget
DB03147Flavin adenine dinucleotideFumarate reductase flavoprotein subunittarget
DB03147Flavin adenine dinucleotideThioredoxin reductasetarget
DB03147Flavin adenine dinucleotide5,10-methylenetetrahydrofolate reductasetarget
DB03147Flavin adenine dinucleotideN,N-dimethylglycine oxidasetarget
DB03147Flavin adenine dinucleotideNADH peroxidasetarget
DB03147Flavin adenine dinucleotideFerredoxin--NADP reductasetarget
DB03147Flavin adenine dinucleotideSulfite reductase [NADPH] flavoprotein alpha-componenttarget
DB03147Flavin adenine dinucleotideFerredoxin--NADP reductasetarget
DB03147Flavin adenine dinucleotideAcyl-CoA dehydrogenase, short-chain specifictarget
DB03147Flavin adenine dinucleotideFerredoxin reductasetarget
DB03147Flavin adenine dinucleotideDihydrolipoyl dehydrogenasetarget
DB03147Flavin adenine dinucleotideAmine oxidase, flavin-containing proteintarget
DB03147Flavin adenine dinucleotideDeoxyribodipyrimidine photo-lyasetarget
DB03147Flavin adenine dinucleotideDeoxyribodipyrimidine photo-lyasetarget
DB03147Flavin adenine dinucleotideL-aspartate oxidasetarget
DB03147Flavin adenine dinucleotideCryptochrome DASHtarget
DB03147Flavin adenine dinucleotideDihydrolipoyl dehydrogenase, mitochondrialtarget
DB03147Flavin adenine dinucleotideFumarate reductase flavoprotein subunittarget
DB03147Flavin adenine dinucleotideNADH-cytochrome b5 reductase 1target
DB03147Flavin adenine dinucleotideOxidoreductasetarget
DB03147Flavin adenine dinucleotideAmine oxidase [flavin-containing] Btarget
DB03147Flavin adenine dinucleotideNADPH:adrenodoxin oxidoreductase, mitochondrialtarget
DB03147Flavin adenine dinucleotidePeroxisomal acyl-coenzyme A oxidase 1target
DB03147Flavin adenine dinucleotideUDP-N-acetylenolpyruvoylglucosamine reductasetarget
DB03147Flavin adenine dinucleotideFAD-linked sulfhydryl oxidase ALRtarget
DB03147Flavin adenine dinucleotideUDP-N-acetylenolpyruvoylglucosamine reductasetarget
DB03147Flavin adenine dinucleotideFlavohemoproteintarget
DB03147Flavin adenine dinucleotidePhenol 2-hydroxylase component Btarget
DB03147Flavin adenine dinucleotideMethylenetetrahydrofolate reductasetarget
DB03147Flavin adenine dinucleotidePutidaredoxin reductasetarget
DB03147Flavin adenine dinucleotideNAD(P)H dehydrogenase (quinone)target
DB03147Flavin adenine dinucleotideUDP-galactopyranose mutasetarget
DB03147Flavin adenine dinucleotide4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerasetarget
DB03147Flavin adenine dinucleotide4-cresol dehydrogenase [hydroxylating] flavoprotein subunittarget
DB03147Flavin adenine dinucleotideAlkyl hydroperoxide reductase subunit Ftarget
DB03147Flavin adenine dinucleotideOuter membrane protein p64k or PM-6target
DB03147Flavin adenine dinucleotideGlutathione reductasetarget
DB03147Flavin adenine dinucleotidePhenylacetone monooxygenasetarget
DB03147Flavin adenine dinucleotideBenzoate 1,2-dioxygenase electron transfer componenttarget
DB03147Flavin adenine dinucleotidePutative acyl-CoA dehydrogenasetarget
DB03147Flavin adenine dinucleotideFkbItarget
DB03147Flavin adenine dinucleotideDihydrolipoyl dehydrogenasetarget
DB03147Flavin adenine dinucleotideDihydrolipoyl dehydrogenasetarget
DB03147Flavin adenine dinucleotideAlkyl hydroperoxide reductase subunit Ftarget
DB03147Flavin adenine dinucleotideFerredoxin--NADP reductasetarget
DB03147Flavin adenine dinucleotideFerredoxin--NADP reductasetarget
DB03147Flavin adenine dinucleotideMersacidin decarboxylasetarget
DB03147Flavin adenine dinucleotideAmine oxidase [flavin-containing] Benzyme
DB03147Flavin adenine dinucleotideNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrialtarget
DB031976-Hydroxymethylpterin2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinasetarget
DB03317Heme CNitrite reductasetarget
DB03317Heme CHigh-molecular-weight cytochrome ctarget
DB03317Heme CCytochrome c''target
DB03317Heme CQuinohemoprotein ethanol dehydrogenase type-1target
DB03317Heme CNitrite reductasetarget
DB03317Heme CCytochrome c4target
DB03317Heme CCytochrome ctarget
DB03317Heme CCytochrome c-552target
DB03317Heme CCytochrome c2target
DB03317Heme CCytochrome c-550target
DB03317Heme CCytochrome c-552target
DB03317Heme CCytochrome c-551target
DB03317Heme CCytochrome c3target
DB03317Heme CSplit-Soret cytochrome ctarget
DB03317Heme CGroup 1 truncated hemoglobin GlbNtarget
DB03317Heme CCytochrome c-553target
DB03317Heme CCytochrome P450 2C9target
DB03317Heme CNine-heme cytochrome ctarget
DB03317Heme CCytochrome c3, 13 kDatarget
DB03317Heme CCytochrome c551 peroxidasetarget
DB03317Heme CCytochrome c3target
DB03317Heme CCytochrome c'target
DB03317Heme CCytochrome c3target
DB03429CardiolipinADP/ATP translocase 1target
DB03469Heme DNitrite reductasetarget
DB03469Heme DNitrite reductasetarget
DB03727Coproporphyrin IUroporphyrinogen decarboxylasetarget
DB03866Prostaglandin G2Prostaglandin G/H synthase 2target
DB03886BiopterinSepiapterin reductasetarget
DB03886Biopterin6-pyruvoyl tetrahydrobiopterin synthasetarget
DB03886BiopterinDihydrofolate reductasetarget
DB04196Pteroic AcidDihydropteroate synthasetarget
DB043457,8-dimethylalloxazineFlavin reductase (NADPH)target
DB043457,8-dimethylalloxazineRiboflavin biosynthesis protein RibFtarget
DB04400L-erythro-7,8-dihydrobiopterinPhenylalanine-4-hydroxylasetarget
DB04400L-erythro-7,8-dihydrobiopterinPteridine reductase 1target
DB04400L-erythro-7,8-dihydrobiopterinNitric oxide synthase, inducibletarget
DB04400L-erythro-7,8-dihydrobiopterinTyrosine 3-monooxygenasetarget
DB04400L-erythro-7,8-dihydrobiopterinPterin-4-alpha-carbinolamine dehydratasetarget
DB04400L-erythro-7,8-dihydrobiopterinDihydroneopterin aldolasetarget
DB044257,8-DihydroneopterinDihydroneopterin aldolasetarget
DB04461Coproporphyrinogen IIIUroporphyrinogen decarboxylasetarget
DB04557Arachidonic AcidProstaglandin G/H synthase 1target
DB04557Arachidonic AcidSerum albumincarrier
DB04557Arachidonic AcidFatty acid-binding protein, adipocytecarrier
DB04557Arachidonic Acid14 kDa fatty acid-binding proteintarget
DB04557Arachidonic AcidFatty acid-binding protein, intestinalcarrier
DB04557Arachidonic AcidCytochrome P450 2C9enzyme
DB04557Arachidonic AcidSolute carrier organic anion transporter family member 2A1transporter
DB04557Arachidonic AcidPeroxisome proliferator-activated receptor alphatarget
DB04557Arachidonic AcidBile acid receptortarget
DB04557Arachidonic AcidRetinoic acid receptor RXR-alphatarget
DB04622N-ACETYLHISTAMINEGlutaminyl-peptide cyclotransferasetarget
DB047895-methyltetrahydrofolic acidAminomethyltransferase, mitochondrialtarget
DB047895-methyltetrahydrofolic acidCanalicular multispecific organic anion transporter 1transporter
DB04803VerdohemeHeme oxygenase 1target
DB04912StannsoporfinHeme oxygenase 1target
DB04912StannsoporfinHeme oxygenase 2target
DB04925DesmoteplasePlasminogentarget
DB04933EritoranToll-like receptor 4target
DB05076FenretinideRetinol-binding protein 4carrier
DB05084AbaloparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget
DB05098LeptinLeptin receptortarget
DB05099AncrodFibrinogen alpha chaintarget
DB05168VintafolideFolate receptor betatarget
DB05168VintafolideFolate receptor gammatarget
DB05168VintafolideFolate receptor alphatarget
DB05229BeraprostProstacyclin receptortarget
DB05229BeraprostCytochrome P450 2C8enzyme
DB05232TetrodotoxinSodium channel protein type 1 subunit alphatarget
DB05232TetrodotoxinSodium channel protein type 2 subunit alphatarget
DB05232TetrodotoxinSodium channel protein type 3 subunit alphatarget
DB05232TetrodotoxinSodium channel protein type 8 subunit alphatarget
DB05258Natural alpha interferonInterferon alpha/beta receptor 1target
DB05262OxypurinolXanthine dehydrogenase/oxidasetarget
DB05299keyhole limpet hemocyaninInterleukin-2target
DB05305Cintredekin BesudotoxInterleukin-13target
DB05332RomiplostimThrombopoietin receptortarget
DB05381HistamineHistamine H1 receptortarget
DB05381HistamineHistamine H2 receptortarget
DB05381HistamineHistamine H3 receptortarget
DB05381HistamineHistamine N-methyltransferaseenzyme
DB05381HistamineSolute carrier family 22 member 2transporter
DB05381HistamineSolute carrier family 22 member 1transporter
DB05381HistamineSolute carrier family 22 member 3transporter
DB05381HistamineSolute carrier family 22 member 5transporter
DB05381HistamineHistamine H4 receptortarget
DB05381HistamineCytochrome P450 2C9enzyme
DB05381HistamineCytochrome P450 2D6enzyme
DB05381HistamineCytochrome P450 3A4enzyme
DB05381HistamineSynaptic vesicular amine transportertarget
DB05413TifuvirtidePlasma serine protease inhibitortarget
DB05428motexafin gadoliniumThioredoxin reductase 1, cytoplasmictarget
DB05428motexafin gadoliniumThioredoxin reductase 2, mitochondrialtarget
DB05428motexafin gadoliniumRibonucleoside-diphosphate reductase subunit M2target
DB05793PRO-542Free fatty acid receptor 4target
DB05875substance PCytochrome P450 19A1enzyme
DB05875substance PCholinesteraseenzyme
DB05875substance PProstaglandin G/H synthase 2enzyme
DB06196IcatibantB2 bradykinin receptortarget
DB06196IcatibantAminopeptidase Ntarget
DB06543AstaxanthinNF-kappa-B inhibitor alphatarget
DB06813PralatrexateFolylpolyglutamate synthase, mitochondrialenzyme
DB06813PralatrexateDihydrofolate reductasetarget
DB06813PralatrexateThymidylate synthasetarget
DB06813PralatrexateFolate transporter 1transporter
DB070313-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acidRetinoic acid receptor gammatarget
DB08455Ro 12-7310Cellular retinoic acid-binding protein 2carrier
DB08819TafluprostProstaglandin F2-alpha receptortarget
DB08819TafluprostProstaglandin G/H synthase 2enzyme
DB08878AminopterinProton-coupled folate transportertransporter
DB08878AminopterinDihydrofolate reductaseenzyme
DB08964GemeprostProstaglandin E2 receptor EP2 subtypetarget
DB08964GemeprostProstaglandin E2 receptor EP3 subtypetarget
DB09046MetreleptinLeptin receptortarget
DB09107Methoxy polyethylene glycol-epoetin betaErythropoietin receptortarget
DB09211LimaprostProstaglandin E2 receptor EP1 subtypetarget
DB09211LimaprostProstaglandin E2 receptor EP2 subtypetarget
DB09211LimaprostProstaglandin E2 receptor EP3 subtypetarget
DB09211LimaprostProstaglandin E2 receptor EP4 subtypetarget
DB11300ThrombinProteinase-activated receptor 1target
DB11300ThrombinProteinase-activated receptor 4target
DB11311ProthrombinFibrinogen alpha chaintarget
DB11311ProthrombinFibrinogen beta chaintarget
DB11311ProthrombinCoagulation factor XIII A chaintarget
DB11311ProthrombinCarboxypeptidase B2target
DB11311ProthrombinCoagulation factor Xenzyme
DB11596LevoleucovorinSerine hydroxymethyltransferasetarget
DB11596LevoleucovorinDihydrofolate reductasetarget
DB11598Antithrombin III humanAntithrombin-IIItarget
DB11601Tuberculin Purified Protein DerivativeToll-like receptor 2target
DB11660Latanoprostene BunodProstaglandin F2-alpha receptortarget
DB11831DinitrochlorobenzeneMethylated-DNA--protein-cysteine methyltransferasetarget
DB11831DinitrochlorobenzeneGlutathione S-transferase Ptarget
DB11858Leukotriene D4Cysteinyl leukotriene receptor 1target
DB11858Leukotriene D4Cysteinyl leukotriene receptor 2target
DB12458MuscimolGamma-aminobutyric acid receptor subunit alpha-1target
DB12458MuscimolGamma-aminobutyric acid receptor subunit beta-3target
DB12458MuscimolGamma-aminobutyric acid receptor subunit gamma-2target
DB12769LometrexolDihydrofolate reductasetarget
DB12789DinoprostProstaglandin D2 receptor 2target
DB12961Leukotriene B4Leukotriene B4 receptor 1target
DB12961Leukotriene B4Leukotriene B4 receptor 2target
DB12961Leukotriene B4Peroxisome proliferator-activated receptor alphatarget
DB13144LenograstimGranulocyte colony-stimulating factor receptortarget
DB13149Protein S humanCoagulation factor Vtarget
DB13149Protein S humanCoagulation factor Xtarget
DB13149Protein S humanVitamin K-dependent protein Ctarget
DB13150Coagulation factor VII humanTissue factortarget
DB13150Coagulation factor VII humanCoagulation factor Xtarget
DB13150Coagulation factor VII humanCoagulation factor IXtarget
DB13192Antihemophilic factor humanCoagulation factor IXtarget
DB13192Antihemophilic factor humanCoagulation factor Xtarget
DB13192Antihemophilic factor humanVitamin K-dependent protein Cenzyme