Biological Factors

Name
Biological Factors
Accession Number
DBCAT000036
Description

Endogenously-synthesized compounds that influence biological processes not otherwise classified under ENZYMES; HORMONES or HORMONE ANTAGONISTS.

Drugs
DrugDrug Description
Denileukin diftitoxA recombinant cytotoxic protein based on a combination of diphtheria toxin fragments and interleukin-2 used to treat cutaneous T-cell lymphoma by targeting the interleukin-2 receptor.
Peginterferon alfa-2aA modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
AlteplaseA recombinant form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli.
Interferon alfa-n1A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus.
Darbepoetin alfaA recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia.
UrokinaseA low molecular weight form of human urokinase used to treat pulmonary embolism and myocardial infarction as well as to clear IV lines.
ReteplaseA purified form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli.
ErythropoietinA recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia.
Interferon alfa-n3A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus.
PegfilgrastimA recombinant human granulocyte colony stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive chemotherapy.
SargramostimA modified form of recombinant human granulocyte-macrophage colony stimulating factor used to increase immune cell production after myelosuppressive therapy or bone marrow transplant.
Peginterferon alfa-2bA purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers.
Antihemophilic factor, human recombinantA form of recombinant coagulation Factor VIII used to treat hemophilia A, von Willebrand disease, and Factor XIII deficiency.
AnakinraA recombinant form of human interleukin-1 receptor antagonist used in the treatment of rheumatoid arthritis and neonatal-onset multisystem inflammatory disease.
AnistreplaseA form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli.
TenecteplaseA modified form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli.
Interferon gamma-1bA form of recombinant human interferon used to treat infections associated with chronic granulomatous disease and to slow the progression of severe malignant osteopetrosis.
Coagulation factor VIIa Recombinant HumanA form of recombinant human coagulation Factor VII used to treat hemophilia A and B.
OprelvekinA form of recombinant interleukin-11 used to stimulate production of megakaryocytes and platelets in patients with or at risk of thrombocytopenia after chemotherapy.
PaliferminA form of recombinant human keratinocyte growth factor used to prevent and treat oral mucositis following radiation or chemotherapy.
AldesleukinA recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma.
Botulinum Toxin Type BA purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea.
Drotrecogin alfaA form of recombinant activated human protein C used to reduce mortality in patients with severe sepsis by inhibiting coagulation Factors V and VIII.
Interferon beta-1aA form of recombinant human interferon used to slow disease progression and reduce the frequency of clinical symptoms in patients who have relapsing multiple sclerosis.
Interferon beta-1bA form of recombinant human interferon used to slow the progression of relapsing multiple sclerosis and to reduce the frequency of clinical symptoms.
Interferon alfacon-1A recombinant interferon similar the interferon alfa subtype which is used to treat hepatitis C infections.
Botulinum toxin type AA purified form of botulinum toxin type A used to block acetylcholine release in the treatment of chronic sialorrhea, muscle spasticity, and dystonia, as well as in cosmetic applications.
StreptokinaseA purified fibrinolytic bacterial protein used to breakdown thrombosis in myocardial infarction, pulmonary embolism, and venous thromboembolism.
FilgrastimA form of recombinant human granulocyte colony stimulating factor used to induce the production of granulocytes and lower infection risk after myelosuppressive therapy.
BecaplerminA recombinant form of human platelet-derived growth factor used to treat ulcers due to diabetic neuropathy in the lower extremities when there is adequate blood supply to the area.
EnfuvirtideAn HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals.
Tetrahydrofolic acidFor nutritional supplementation, also for treating dietary shortage or imbalance.
RiboflavinA vitamin used to correct vitamin B2 deficiency.
Dihomo-gamma-linolenic acidFor nutritional supplementation, also for treating dietary shortage or imbalance
Folic acidA nutrient used to treat megaloblastic anemia and is found in many supplements.
IcosapentA polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements.
Vitamin AA vitamin important for retinal function that is used clinically to correct vitamin A deficiency.
SapropterinA cofactor used as an adjunct to phenylalanine restriction in the treatment of phenylketonuria (PKU).
TreprostinilA prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol.
Carboprost tromethamineA prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective.
AcitretinAn oral retinoid used in the treatment of severe psoriasis.
VerteporfinA benzoporphyrin derivative used to treat pathological myopia, ocular histoplasmosis, and choroidal neovascularization in macular degeneration.
AlitretinoinA vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis.
MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
AdenosineA medication used in myocardial perfusion scintigraphy.
LeucovorinA folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer.
LatanoprostAn isopropyl ester prodrug used to treat increased intraocular pressure.
Porfimer sodiumA hematoporphyrin derivative used to treat esophageal cancer, endobronchial cancer, and high grade dysplasia in Barrett's Esophagus.
TretinoinA vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles.
AlprostadilA medication used to treat erectile dysfunction.
BimatoprostA prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension.
DinoprostoneA prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease.
EtretinateFor the treatment of severe psoriasis in adults.
MisoprostolA prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers.
IsotretinoinA retinoid used to treat severe recalcitrant acne.
LubiprostoneA prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use.
IloprostA synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH).
Dinoprost tromethamineUsed for aborting second-trimester pregnancy (between the twelfth to eighteenth week of gestation) and in incomplete abortion or for therapeutic abortion in cases of intrauterine fetal death and congenital abnormalities...
EpoprostenolA vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure.
ExenatideA GLP-1 agonist used in the management of type 2 diabetes mellitus.
MecaserminA recombinant insulin-like growth factor-1 used for the long-term treatment of growth failure in pediatric patients with primary IGF-1 deficiency or with growth hormone gene deletion due to the development of neutralizing antibodies to GH.
CalciumA mineral found in over-the-counter supplements or prescription formulations used for the treatment of specific medical conditions related to calcium deficiency.
5-Methoxy-N,N-diisopropyltryptamine5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a...
BufotenineA hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a...
Bacteriochlorophyll AA specific bacteriochlorophyll that is similar in structure to CHLOROPHYLL A.
N-MethylmesoporphyrinN-methylmesoporphyrin is a solid. This compound belongs to the porphyrins. These are compounds containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to...
6-Hydroxymethyl-7,8-DihydropterinNot Available
Chlorophyll ANot Available
Platelet Activating FactorNot Available
ProtoporphyrinNot Available
Prostaglandin B2Not Available
D-threo-neopterinA pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections. (From Stedman, 26th ed) Neopterin also serves as a...
Hydrogenobyrinic acidNot Available
MesohemeThe color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.
4-OxoretinolNot Available
SirohemeNot Available
Arotinoid acidArotinoid acid is a retinoic acid analog which acts as a selective RAR agonist.
PeridininNot Available
Flavin adenine dinucleotideA coenzyme form of vitamin B2 used in clinical conditions associated with vitamin B2 deficiency.
6-HydroxymethylpterinNot Available
Ferroheme CNot Available
HeminAn iron-containing porphyrin injection used for the relief of recurrent attacks of acute intermittent porphyria (AIP) associated with the menstrual cycle when carbohydrate therapy is not effective.
DiacetyldeuterohemeNot Available
ViolaxanthinNot Available
Heme DNot Available
Coproporphyrin INot Available
Prostaglandin G2A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem]
BiopterinA natural product that has been considered as a growth factor for some insects. [PubChem]
Coenzyme F420Not Available
Pteroic acidNot Available
LumichromeNot Available
L-erythro-7,8-dihydrobiopterin7,8-Dihydrobiopterin is an inhibitor of the enzyme dihydroneopterin aldolase (DHNA), which catalyzes the conversion of 7,8-Dihydrobiopterin to 6-hydroxymethyl-7,8-dihydropterin and glycolaldehyde.
7,8-DihydroneopterinNot Available
Coproporphyrinogen IIINot Available
Chlorophyll BA light, silvery, metallic element. It has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. Its salts are essential in nutrition, being required for the activity of...
Arachidonic AcidAn unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides....
N-acetylhistamineNot Available
VerdohemeNot Available
StannsoporfinInvestigated for use/treatment in liver disease, metabolic disease, and pediatric indications.
DesmoteplaseInvestigated for use/treatment in cerebral ischemia and strokes.
EritoranInvestigated for use/treatment in sepsis and septicemia.
LemuteporfinIntended for the treatment of benign prostatic hyperplasia and prostrate disorders.
AdecatumumabInvestigated for use/treatment in breast cancer and prostate cancer.
FenretinideInvestigated for use/treatment in macular degeneration.
AbaloparatideA parathyroid hormone-related protein (PTHrP) analog used for the treatment of osteoporosis in postmenopausal women with a high risk of fracture.
LeptinInvestigated for use/treatment in lipodystrophy and obesity.
AncrodAn anticoagulant purified from the venom of the Malayan pit viper that functions by inactivating circulating plasma fibrinogen. Not currently approved for use or marketed in any country.
TopsalysinInvestigated for use/treatment in benign prostatic hyperplasia, cancer/tumors (unspecified), prostate cancer, prostate disorders, and solid tumors.
VintafolideInvestigated for use/treatment in solid tumors.
BeraprostFor the treatment of pulmonary hypertension.
TetrodotoxinFor the treatment of chronic and breakthrough pain in advanced cancer patients as well as for the treatment of opioid dependence.
Interferon alfaInvestigated for use/treatment in hepatitis (viral, C), leukemia (lymphoid), leukemia (myeloid), leukemia (unspecified), and melanoma.
Motexafin lutetiumInvestigated for use/treatment in brain cancer, breast cancer, cervical dysplasia/cancer, prostate cancer, cancer/tumors (unspecified), coronary artery disease, macular degeneration, and peripheral vascular disease.
keyhole limpet hemocyaninInvestigated for use/treatment in bladder cancer and solid tumors.
Cintredekin BesudotoxInvestigated for use/treatment in brain cancer.
RomiplostimA fusion protein thrombopoietin (TPO) peptide analog that increases platelet counts by binding to and activating the human TPO receptor. Used to treat thrombocytopenia associated with chronic immune thrombocytopenia (ITP).
Ciliary neurotrophic factorInvestigated for use/treatment in eye disorders/infections, macular degeneration, and retinal disorders (unspecified).
HistamineAn ingredient of topical drugs for the relief of joint pain or muscle aches and pains.
Albinterferon Alfa-2BInvestigated for use/treatment in hepatitis (viral, C).
TifuvirtideInvestigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.
Motexafin gadoliniumInvestigated for use/treatment in brain cancer, cancer/tumors (unspecified), lung cancer, and lymphoma (non-hodgkin's).
CobiprostoneInvestigated for use/treatment in cystic fibrosis.
PraconaseInvestigated for use/treatment in spinal cord injuries.
Fibroblast growth factor-1Investigated for use/treatment in coronary artery disease and peripheral vascular disease.
4'-Methylene-5,8,10-trideazaaminopterinInvestigated for use/treatment in inflammatory disorders (unspecified), psoriasis and psoriatic disorders, and rheumatoid arthritis.
IRX-2Investigated for use/treatment in cancer/tumors (unspecified), head and neck cancer, and solid tumors.
IRX-5183Investigated for use/treatment in adverse effects (chemotherapy) and blood (blood forming organ disorders, unspecified).
Maxy-G34Investigated for use/treatment in adverse effects (chemotherapy) and neutropenics.
PRO-542Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections, HIV infection, and pediatric indications.
AEOL 10150Investigated for use/treatment in amyotrophic lateral sclerosis (ALS).
CTCE-0214Investigated for use/treatment in adverse effects (chemotherapy), blood (blood forming organ disorders, unspecified), cancer/tumors (unspecified), neutropenics, and vascular diseases.
GI-5005Investigated for use/treatment in hepatitis (viral, C).
TranscrocetinateInvestigated for use/treatment in cancer/tumors (unspecified), hemorrhage, hypoxia, respiratory failure, and strokes.
IRL-1620Investigated for use/treatment in cancer/tumors (unspecified).
TalotrexinInvestigated for use/treatment in solid tumors, lung cancer, leukemia (unspecified), and leukemia (lymphoid).
IcatibantA bradykinin B2 receptor antagonist used to treat acute episodes of swelling and inflammation associated with hereditary angioedema (HAE).
TraferminInvestigated for use/treatment in coronary artery disease, peripheral vascular disease, periodontal disease, bone fractures, entero-related fistulae, and diabetic foot ulcers.
LanoteplaseInvestigated for use/treatment in myocardial infarction.
EndostatinInvestigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy.
RepiferminInvestigated for use/treatment in bone marrow transplant, ulcers, and inflammatory bowel disease.
E5531Investigated for use/treatment in sepsis and septicemia.
VelaferminInvestigated for use/treatment in adverse effects (chemotherapy).
ThrombopoietinInvestigated for use/treatment in thrombocytopenia.
AstaxanthinInvestigated for use/treatment in eye disorders/infections, cancer/tumors (unspecified), and asthma.
LabradimilInvestigated for use/treatment in brain cancer and pediatric indications.
EmfilerminInvestigated for use/treatment in adverse effects (chemotherapy), reproductive health, and infertility.
RostaporfinInvestigated for use/treatment in macular degeneration.
AmediplaseInvestigated for use/treatment in myocardial infarction and thrombosis.
Beta caroteneA vitamin A precursor found in various nutritional supplements and health products.
SaralasinNot Annotated
PralatrexateAn antineoplastic agent used for the treatment of relapsed or refractory peripheral T-cell lymphoma.
UnoprostoneA prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents.
3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acidNot Available
Ro 12-7310Not Available
TafluprostAn ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
SerotoninFor temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.
Leukotriene C4The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates...
AminopterinPrior to its withdrawal, aminopterin was initially used in the treatment of childhood leukemia; specifically to induce remissions. Later, aminopterin was used off-label in the United States to treat psoriasis,...
Icosapent ethylAn ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia.
GemeprostIndicated for the softening and dilatation of the cervix uteri prior to transcervical, intrauterine operative procedures in the first trimester of pregnancy or facilitating therapeutic termination of pregnancy in patients...
BatroxobinNo approved indications. Batroxobin is a defibrongenating agent which has been observed to reduce fibrinogen levels and thus reduce clot risk when used intravenously.
CarbazochromeIndicated for capillary and parenchymal hemorrhage (trauma, tonsillectomy, during surgery), intestinal bleeding, and thrombocytopenic purpura.
MetreleptinA leptin analogue used as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy.
AncestimA human stem cell factor used in combination with filgrastim during autologous peripheral blood progenitor cell (PBPC) transplantation to increase PBPC mobilization for improved collection.
Methoxy polyethylene glycol-epoetin betaA synthetic erythropoiesis stimulating agent (ESA) used to treat anemia associated with chronic kidney disease.
Turoctocog alfaAn antihemorrhagic agent used for the treatment and prophylaxis of bleeding in patients of all ages with haemophilia A (congenital factor VIII deficiency).
Peginterferon beta-1aAn interferon beta used to treat relapsing forms of multiple sclerosis.
LimaprostLimaprost is used for the improvement of various ischemic symptoms such as ulcer, pain and feeling of coldness associated with thromboangiitis obliterans as well as improvement of subjective symptoms (pain...
Fibrinogen humanA hemostatic agent used for the treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.
Omega-3-acid ethyl estersA mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia.
Bordetella pertussis pertactin antigenBordetella pertussis pertactin antigen is a vaccine for the prophylaxis of whooping cough that contains pertactin, a membrane-associated antigen of Bordetella pertussis .
ZeaxanthinZeaxanthin is a most common carotenoid alcohols found in nature that is involved in the xanthophyll cycle. As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some...
LycopeneAn ingredient found in a variety of supplements and vitamins.
Xanthan gumXanthan gum is a polysaccharide gum derived from* Xanthomonas campestris* by a pure-culture fermentation process and purified by recovery with isopropyl alcohol. The major constituents include D-glucose, D-mannose, and D-glucuronic...
ThrombinA coagulation factor used to stop bleeding during surgery.
ProthrombinA coagulation factor used for emergency reversal of vitamin K antagonist therapy.
Protein CA medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis.
Factor IX Complex (Human)A Factor IX complex used to prevent and treat bleeding episodes in hemophilia B or vitamin K antagonist therapy.
BambermycinsBambermycins are antibiotic complexes which are retrieved from the organism, Streptomyces bambergiensis. They are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics...
FenprostaleneNot Annotated
LuprostiolNot Annotated
ProstaleneAnalog of prostaglandin F2 alpha.
ZeranolZeranol is a non-steroidal estrogen agonist. It is a mycotoxin, derived from fungi in the Fusarium family, and may be found as a contaminant in fungus-infected crops. It is 3-4x...
CloprostenolNot Annotated
FluprostenolNot Annotated
LevoleucovorinA folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer.
Antithrombin III humanAn alpha-2-glycoprotein used to prevent thromboembolisms in patients with hereditary antithrombin III deficiency.
Tuberculin purified protein derivativeA purified protein used in the Mantoux test for Mycobacterium tuberculosis testing.
Epoetin deltaEpoetin Delta is an ingredient in the EMA-withdrawn product Dynepo.
TemoporfinA photosensitizer used to treat squamous cell carcinomas of the head and neck.
Eptotermin AlfaA bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin Alfa is an ingredient in...
Dibotermin alfaindicated for the treatment of acute tibia fractures in adults, as an adjunct to standard care using open fracture reduction and intramedullary unreamed nail fixation [FDA Label]. indicated for single-level...
Recombinant Cholera Toxin B SubunitRecombinant Cholera Toxin B Subunit is an ingredient in the EMA-authorised product Dukoral.
Latanoprostene bunodA prostaglandin analog used to reduce ocular hypertension or treat open-angle glaucoma.
Rusalatide acetateChrysalin has been used in trials studying the treatment of Radius Fracture.
BombesinBombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and...
CenderitideCenderitide is under investigation for the treatment of ST Elevation (STEMI) Myocardial Infarction of Anterior Wall.
TalaporfinTalaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia.
DinitrochlorobenzeneDinitrochlorobenzene has been used in trials studying the treatment of HIV Infections.
Angiotensin IIA peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock.
Leukotriene D4Leukotriene D4 has been used in trials studying the diagnostic of Asthma and Allergic Rhinitis.
CrocinCrocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia.
CilengitideCilengitide has been used in trials studying the treatment of Sarcoma, Gliomas, Lymphoma, Leukemia, and Lung Cancer, among others.
AvoterminJuvista has been investigated for the treatment, prevention, and basic science of Scars, Keloid, and Cicatrix.
TAK-448TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.
Interleukin-7Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer.
NagrestipenNagrestipen has been used in trials studying the treatment of CANCER, Neoplasm, Metastasis, Radiation Oncology, and Neoplasm Metastasis.
Zuretinol acetateZuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis).
BradykininBradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.
BinetrakinBinetrakin has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and Leukemia, Acute Myelogenous (AML), among others.
EpofolateEpofolate has been used in trials studying the treatment of Advanced Solid Tumors.
DulanerminDulanermin has been used in trials studying the treatment of Colorectal Cancer, Non-Hodgkin's Lymphoma, and Metastatic Colorectal Cancer.
Vatreptacog alfaVatreptacog Alfa (Activated) has been used in trials studying the treatment of Haemophilia B, Haemophilia A, Congenital Bleeding Disorder, Haemophilia A With Inhibitors, and Haemophilia B With Inhibitors.
MuplestimMuplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in...
MuscimolMuscimol has been used in trials studying the treatment of Epilepsy and Parkinson's Disease.
MolgramostimMolgramostim has been used in trials studying the treatment of Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and Autoimmune Pulmonary Alveolar Proteinosis.
RonopterinRonopterin has been used in trials studying the treatment of Traumatic Brain Injury.
SpriferminSprifermin has been used in trials studying the treatment of Osteoarthritis, Knee and Cartilage Injury of Knee.
Nerve Growth FactorNerve Growth Factor has been used in trials studying the prevention and treatment of Mental Handicap, Alzheimer's Disease, Traumatic Brain Injury, Cerebral Palsy Children, and Delayed Speech Development, among others.
Endothelin-1Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).
AviscumineCy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy).
BalugrastimBalugrastim has been used in trials studying the treatment of Solid Tumors.
SulprostoneSulprostone has been used in trials studying Abortion, Induced.
MonteplaseMonteplase has been used in trials studying the treatment of Pulmonary Embolism.
LometrexolLometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.
DinoprostA medication used to induce a second trimester abortion.
Naptumomab EstafenatoxNaptumomab Estafenatox has been used in trials studying the treatment of Pancreatic Cancer, Renal Cell Carcinoma, and Non-Small-Cell Lung Carcinoma.
Interleukin-10Interleukin-10 has been used in trials studying the prevention and treatment of Vasculitis, Pancreatitis, Bile Duct Diseases, Pancreatic Diseases, and Gallbladder Diseases, among others.
Factor XIII (human)A purified form of Factor XIII that is used to prevent and treat surgical bleeding in patients with a Factor XIII deficiency.
Leukotriene B4Leukotriene B4 has been used in trials studying the treatment of HIV Infections.
NeosaxitoxinNeosaxitoxin is under investigation in clinical trial NCT01786655 (Safety Study of Long-Acting Local Anesthetic).
Resolvin E1Resolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers).
Von Willebrand Factor HumanA complex of von Willebrand Factor and Factor VIII used to treat bleeding episodes in von Willebrand disease.
LenograstimThe drug is used to reduce the risk of life-threatening infection in patients with neutropenia, particularly after cytotoxic chemotherapy. Lenograstim is indicated as a treatment to reduce the duration of...
Coagulation factor X humanA coagulation factor used to treat Factor X deficiency to control bleeding.
Protein S humanA medication used for emergency reversal of coagulation factor deficiency in vitamin K antagonist therapy.
Coagulation factor VII humanA coagulation factor used to treat bleeding disorders such as hemophilia and Glanzmann's thrombasthenia.
Antihemophilic factor humanA Factor VIII replacement therapy used to treat hemophilia A.
KallidinogenaseNot Annotated
LipegfilgrastimA medication used to reduce the duration of chemotherapy-induced neutropenia and incidence of febrile neutropenia in cytotoxic chemotherapy.
Trenonacog alfaHuman coagulation factor IX (EC 3.4.21.22, Christmas factor, plasma thromboplastin component), produced in CHO cells.
MotretinideNot Annotated
HematinNot Annotated
AngiotensinamideNot Annotated
IprazochromeNot Annotated
SaruplaseNot Annotated
EnprostilNot Annotated
Meningococcal polysaccharide vaccine group AMeningococcal group A polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup A. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and...
Meningococcal polysaccharide vaccine group CMeningococcal group C polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup C. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and...
Nonacog beta pegolA recombinant coagulation Factor IX derivative used to treat hemophilia B.
Moroctocog alfaA recombinant Factor VIII used to treat hemophilia A to control bleeding.
Interleukin-1 alpha, human recombinantNot Annotated
13-cis-12-(3'-Carboxyphenyl)retinoic acidNot Annotated
Basic Fibroblast Growth FactorBasic Fibroblast Growth Factor is not currently approved for any FDA or Health Canada approved indications.
p-PhenylenediamineNot Annotated
NepiderminNot Annotated
Insulin-like growth factor IIThe insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. This factor presents effects related to growth...
Beroctocog alfaBeroctocog alfa is indicated for the prevention and control of bleeding in patients with hemophilia A or acquired Factor VIII (FVIII) deficiency. It is also indicated for surgical/invasive procedures in...
Andexanet alfaA recombinant Factor Xa used to reverse anticoagulation caused by rivaroxaban and apixaban.
Antihemophilic Factor (Recombinant), PEGylatedFor the management of hemophilia A (congenital factor VIII deficiency) [FDA label], . This medication is a human antihemophilic factor indicated in adolescent and adult patients (12 years and older)...
alpha-Conotoxin VC 1.1Investigated for use/treatment in pain (acute or chronic).
LuteinXanthophylls are taken for nutritional supplementation, and also for treating dietary shortage or imbalance.
Prostaglandin D2The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important...
Flavin mononucleotideA form of vitamin B2 used to restore riboflavin in anemia, migraine, alcoholism, and hyperhomocysteinemia.
N-acetylserotoninNot Available
Hepatitis B Vaccine (Recombinant)A solution of Hepatitis B surface antigen used to immunize patients against Hepatitis B.
Riboflavin tetrabutyrateNot Annotated
Turoctocog alfa pegolTuroctocog alfa pegol (N8-GP) is indicated for use in adults and children of all ages with hemophilia A (congenital factor VIII deficiency) for routine prophylaxis in reducing the frequency of...
Methoxy arachidonyl fluorophosphonateMethoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid...
RegramostimInvestigated for use/treatment in adverse effects (chemotherapy) and bone marrow transplant.
Sar9, Met (O2)11-Substance PInvestigated for use/treatment in acute respiratory distress syndrome (ARDS) and viral infection.
Peginterferon lambda-1aPeginterferon lambda-1a is under investigation in clinical trial NCT01754974 (Safety and Efficacy Study of Peginterferon Lambda-1a vs. Peginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C).
Human interleukin-2Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).
Human interferon betaA polypeptide drug used in the treatment of relapsing forms of Multiple Sclerosis (MS).
Recombinant CD40-ligandRecombinant CD40-ligand is under investigation in clinical trial NCT00053391 (Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma).
NeopterinNeopterin is under investigation in clinical trial NCT02974192 (Neopterin Effects on Ischemic Stroke).
AnfibatideAnfibatide is under investigation in clinical trial NCT01585259 (Anfibatide Phase Ib-IIa Clinical Trial).
LeridistimLeridistim is under investigation in clinical trial NCT00004215 (Leridistim Compared With Filgrastim in Treating Older Patients With Acute Myeloid Leukemia).
Interferon alfa-2cInterferon alfa-2c is under investigation in clinical trial NCT00485563 (A Phase II Study of EC17 (Folate-hapten Conjugate) in Patients With Progressive Metastatic Renal Cell Carcinoma).
NorbixinNorbixin is under investigation in clinical trial NCT03820245 (Effect of Short-term Annatto Carotenoids Supplementation on Oxidative Stress Status in Healthy Individuals).
ChlorotoxinChlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma).
2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a is under investigation in clinical trial NCT01668823 (Photodynamic Therapy in Treating Patients With Lung Cancer).
BevifimodBevifimod is under investigation in clinical trial NCT01749787 (Safety Study of PRTX-100 With Methotrexate or Leflunomide to Treat Active Rheumatoid Arthritis).
TozuleristideTozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery).
ALT-801ALT-801 is under investigation in clinical trial NCT01478074 (ALT-801-activated Natural Killer Cells After FLAG Induction for Acute Myeloid Leukemia).
Tucotuzumab celmoleukinTucotuzumab celmoleukin is under investigation in clinical trial NCT00016237 (Interleukin-2 Combined With Monoclonal Antibody Therapy in Treating Patients With Kidney, Bladder, or Lung Cancer That Has Not Responded to Previous...
Lorukafusp alfaLorukafusp alfa is under investigation in clinical trial NCT01334515 (Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma).
FucoxanthinFucoxanthin is under investigation in clinical trial NCT03613740 (Effect of Fucoxanthin on the Components of the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion).
BexaroteneA retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy.
5-methyltetrahydrofolic acid5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases (also called methionine...
Chlorotoxin I-131Investigated for use/treatment in various forms of brain cancer; Malignant Glioma, Glioblastoma Multiforme, GBM, Anaplastic Astrocytoma, Oligo-Astrocytoma, Gliosarcoma
Levomefolic acidA folate supplement used to prevent neural tube defects in pregnancy or folate deficiency.
Soy sterolNot Annotated
Thrombin alfaA platelet activating factor used to treat minor bleeding.
Eftrenonacog alfaA recombinant Factor IX used to treat and prevent bleeding in hemophilia B.
Angiotensin 1-7TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities.
EndostarEndostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
AclerastideAclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic.
Anti-inhibitor coagulant complexA medication used to control bleeding episodes and prevent bleeding episodes in hemophilia A and B.
Albutrepenonacog alfaA recombinant Factor IX fused to recombinant human albumin used to treat hemophilia B.
Axicabtagene ciloleucelA CAR T cell therapy for relapsed or refractory large B-cell lymphoma, diffuse large B-cell lymphoma, primary mediastinal large B-cell lymphoma, high grade B-cell lymphoma, and diffuse large B-cell lymphoma from follicular lymphoma.
beta-SitosterolActive fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity.
EdasalonexentEdasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes).
BempegaldesleukinBempegaldesleukin is under investigation in clinical trial NCT03729245 (A Study of NKTR-214 in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib...
PegilodecakinPegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
PegbelferminPegbelfermin is under investigation in clinical trial NCT03486899 (A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver Fibrosis).
O-(N-acetyl-alpha-D-galactosaminyl)-L-serineNot Available
PadeliporfinNot Annotated
Human blood group H type 1 trisaccharideNot Available
PatulinNot Annotated
6-hydroxy-FADNot Available
Anhydrovitamin ANot Available
TricetinNot Available
LumiflavinNot Available
N-EthylretinamideN-Ethylretinamide is the ethylamide of all-trans B-retinoic acid.
Edodekin alfaEdodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic, or...
Drugs & Drug Targets
DrugTargetType
Denileukin diftitoxInterleukin-2 receptor subunit alphatarget
Denileukin diftitoxCytokine receptor common subunit gammatarget
Denileukin diftitoxInterleukin-2 receptor subunit betatarget
Peginterferon alfa-2aInterferon alpha/beta receptor 2target
Peginterferon alfa-2aInterferon alpha/beta receptor 1target
Peginterferon alfa-2aCytochrome P450 1A2enzyme
AlteplaseUrokinase plasminogen activator surface receptortarget
AlteplaseFibrinogen alpha chaintarget
AlteplasePlasminogentarget
AlteplasePlasminogen activator inhibitor 1target
Interferon alfa-n1Interferon alpha/beta receptor 2target
Interferon alfa-n1Interferon alpha/beta receptor 1target
Interferon alfa-n1Cytochrome P450 1A2enzyme
Darbepoetin alfaErythropoietin receptortarget
UrokinaseUrokinase plasminogen activator surface receptortarget
UrokinasePlasminogentarget
UrokinasePlasminogen activator inhibitor 2target
UrokinasePlasminogen activator inhibitor 1target
UrokinasePlasma serine protease inhibitortarget
UrokinaseNidogen-1target
UrokinaseLow-density lipoprotein receptor-related protein 2target
UrokinaseSuppressor of tumorigenicity 14 proteintarget
UrokinaseMacrophage metalloelastaseenzyme
ReteplaseFibrinogen alpha chaintarget
ReteplasePlasminogentarget
ReteplasePlasminogen activator inhibitor 1target
ErythropoietinErythropoietin receptortarget
Interferon alfa-n3Interferon alpha/beta receptor 1target
Interferon alfa-n3Interferon alpha/beta receptor 2target
Interferon alfa-n3Cytochrome P450 1A2enzyme
PegfilgrastimGranulocyte colony-stimulating factor receptortarget
PegfilgrastimNeutrophil elastaseenzyme
SargramostimGranulocyte-macrophage colony-stimulating factor receptor subunit alphatarget
SargramostimBone marrow proteoglycantarget
SargramostimInterleukin-3 receptor subunit alphatarget
SargramostimCytokine receptor common subunit betatarget
SargramostimSyndecan-2target
Peginterferon alfa-2bInterferon alpha/beta receptor 1target
Peginterferon alfa-2bInterferon alpha/beta receptor 2target
Peginterferon alfa-2bCytochrome P450 1A2enzyme
Peginterferon alfa-2bCytochrome P450 2D6enzyme
Peginterferon alfa-2bCytochrome P450 2C9enzyme
Antihemophilic factor, human recombinantCoagulation factor Xtarget
Antihemophilic factor, human recombinantPhytanoyl-CoA dioxygenase, peroxisomaltarget
Antihemophilic factor, human recombinantCoagulation factor IXtarget
Antihemophilic factor, human recombinantAsialoglycoprotein receptor 2target
Antihemophilic factor, human recombinant78 kDa glucose-regulated proteintarget
Antihemophilic factor, human recombinantCalreticulintarget
Antihemophilic factor, human recombinantCalnexintarget
Antihemophilic factor, human recombinantProtein ERGIC-53target
Antihemophilic factor, human recombinantProlow-density lipoprotein receptor-related protein 1target
Antihemophilic factor, human recombinantMultiple coagulation factor deficiency protein 2target
Antihemophilic factor, human recombinantvon Willebrand factortarget
Antihemophilic factor, human recombinantProthrombinenzyme
Antihemophilic factor, human recombinantVitamin K-dependent protein Cenzyme
AnakinraInterleukin-1 receptor type 1target
AnistreplaseFibrinogen alpha chaintarget
AnistreplasePlasminogentarget
AnistreplasePlasminogen activator inhibitor 1target
TenecteplaseUrokinase plasminogen activator surface receptortarget
TenecteplasePlasminogen activator inhibitor 1target
TenecteplaseFibrinogen alpha chaintarget
TenecteplasePlasminogen activator inhibitor 2target
TenecteplaseTetranectintarget
TenecteplaseKeratin, type II cytoskeletal 8target
TenecteplaseAnnexin A2target
TenecteplaseCalreticulintarget
TenecteplaseCalnexintarget
TenecteplaseProlow-density lipoprotein receptor-related protein 1target
TenecteplasePlasminogentarget
Interferon gamma-1bInterferon gamma receptor 1target
Interferon gamma-1bInterferon gamma receptor 2target
Interferon gamma-1bCytochrome P450 1A2enzyme
Coagulation factor VIIa Recombinant HumanCoagulation factor Xtarget
Coagulation factor VIIa Recombinant HumanTissue factortarget
Coagulation factor VIIa Recombinant HumanTissue factor pathway inhibitortarget
Coagulation factor VIIa Recombinant HumanVitamin K-dependent gamma-carboxylasetarget
Coagulation factor VIIa Recombinant HumanCoagulation factor VIItarget
OprelvekinInterleukin-11 receptor subunit alphatarget
PaliferminFibroblast growth factor receptor 2target
PaliferminNeuropilin-1target
PaliferminFibroblast growth factor receptor 1target
PaliferminFibroblast growth factor receptor 4target
PaliferminFibroblast growth factor receptor 3target
PaliferminBasement membrane-specific heparan sulfate proteoglycan core proteintarget
AldesleukinInterleukin-2 receptor subunit betatarget
AldesleukinInterleukin-2 receptor subunit alphatarget
AldesleukinCytokine receptor common subunit gammatarget
AldesleukinProstaglandin G/H synthase 2enzyme
AldesleukinCytosolic phospholipase A2enzyme
AldesleukinCytochrome P450 3A4enzyme
AldesleukinXanthine dehydrogenase/oxidaseenzyme
AldesleukinCytochrome P450 2E1enzyme
Botulinum Toxin Type BVesicle-associated membrane protein 1target
Botulinum Toxin Type BVesicle-associated membrane protein 2target
Botulinum Toxin Type BSynaptotagmin-2target
Drotrecogin alfaCoagulation factor VIIItarget
Drotrecogin alfaCoagulation factor Vtarget
Drotrecogin alfaPlasminogen activator inhibitor 1target
Drotrecogin alfaThrombomodulintarget
Drotrecogin alfaVitamin K-dependent protein Starget
Drotrecogin alfaProthrombintarget
Drotrecogin alfaPlatelet factor 4target
Drotrecogin alfaPlasma serine protease inhibitortarget
Drotrecogin alfaSerpin B6target
Drotrecogin alfaEndothelial protein C receptortarget
Interferon beta-1aInterferon alpha/beta receptor 1target
Interferon beta-1aInterferon alpha/beta receptor 2target
Interferon beta-1aCytochrome P450 1A2enzyme
Interferon beta-1bInterferon alpha/beta receptor 1target
Interferon beta-1bInterferon alpha/beta receptor 2target
Interferon beta-1bCytochrome P450 1A2enzyme
Interferon alfacon-1Interferon alpha/beta receptor 1target
Interferon alfacon-1Interferon alpha/beta receptor 2target
Interferon alfacon-1Cytochrome P450 1A2enzyme
Botulinum toxin type ASynaptosomal-associated protein 25target
Botulinum toxin type ARho-related GTP-binding protein RhoBtarget
StreptokinasePlasminogentarget
StreptokinaseProteinase-activated receptor 1target
StreptokinaseCytosolic phospholipase A2enzyme
FilgrastimGranulocyte colony-stimulating factor receptortarget
FilgrastimNeutrophil elastasetarget
BecaplerminPlatelet-derived growth factor receptor betatarget
BecaplerminAlpha-2-macroglobulintarget
BecaplerminPlatelet-derived growth factor receptor alphatarget
EnfuvirtideEnvelope glycoproteintarget
EnfuvirtideCytochrome P450 2C19enzyme
EnfuvirtideCytochrome P450 2E1enzyme
Tetrahydrofolic acidC-1-tetrahydrofolate synthase, cytoplasmictarget
Tetrahydrofolic acidBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrialtarget
Tetrahydrofolic acidAminomethyltransferase, mitochondrialtarget
Tetrahydrofolic acidCytosolic 10-formyltetrahydrofolate dehydrogenasetarget
Tetrahydrofolic acidMethionine synthasetarget
Tetrahydrofolic acidFormimidoyltransferase-cyclodeaminasetarget
Tetrahydrofolic acidBifunctional purine biosynthesis protein PURHtarget
Tetrahydrofolic acidSerine hydroxymethyltransferase, cytosolictarget
Tetrahydrofolic acidSerine hydroxymethyltransferase, mitochondrialtarget
Tetrahydrofolic acidMethylenetetrahydrofolate reductasetarget
Tetrahydrofolic acidSerine hydroxymethyltransferasetarget
Tetrahydrofolic acidMethionyl-tRNA formyltransferase, mitochondrialtarget
Tetrahydrofolic acidCanalicular multispecific organic anion transporter 1transporter
RiboflavinFlavin reductase (NADPH)target
RiboflavinRiboflavin kinasetarget
RiboflavinRiboflavin synthasetarget
RiboflavinAmine oxidase [flavin-containing] Aenzyme
RiboflavinMethylenetetrahydrofolate reductaseenzyme
RiboflavinSolute carrier family 22 member 6transporter
Dihomo-gamma-linolenic acidProstaglandin G/H synthase 2target
Dihomo-gamma-linolenic acidProstaglandin G/H synthase 1target
Dihomo-gamma-linolenic acidFatty acid-binding protein, braincarrier
Folic acidFolate receptor gammatarget
Folic acidFolate receptor betatarget
Folic acidMethylenetetrahydrofolate reductaseenzyme
Folic acidMultidrug resistance-associated protein 4transporter
Folic acidSolute carrier family 22 member 6transporter
Folic acidCanalicular multispecific organic anion transporter 2transporter
Folic acidATP-binding cassette sub-family C member 11transporter
Folic acidATP-binding cassette sub-family G member 2transporter
Folic acidProton-coupled folate transportertransporter
Folic acidMitochondrial folate transporter/carriertransporter
Folic acidGamma-glutamyl hydrolaseenzyme
Folic acidFolate receptor alphatarget
Folic acidDihydrofolate reductaseenzyme
IcosapentProstaglandin G/H synthase 2target
IcosapentProstaglandin G/H synthase 1target
IcosapentFree fatty acid receptor 1target
IcosapentFatty acid-binding protein, braincarrier
IcosapentFatty acid desaturase 1target
IcosapentLong-chain-fatty-acid--CoA ligase 4target
IcosapentSodium/calcium exchanger 1target
IcosapentPeroxisome proliferator-activated receptor gammatarget
IcosapentPeroxisome proliferator-activated receptor deltatarget
IcosapentTransient receptor potential cation channel subfamily V member 1target
IcosapentPeroxisome proliferator-activated receptor alphatarget
IcosapentSerum albumincarrier
Vitamin ARetinol dehydrogenase 12target
Vitamin A11-cis retinol dehydrogenasetarget
Vitamin ARetinol dehydrogenase 13target
Vitamin ARetinol-binding protein 5carrier
Vitamin ARetinoid-binding protein 7carrier
Vitamin ARetinol-binding protein 4carrier
Vitamin ARetinol-binding protein 2carrier
Vitamin ARetinal dehydrogenase 2target
Vitamin ARetinal dehydrogenase 1target
Vitamin ALecithin retinol acyltransferasetarget
Vitamin AShort-chain dehydrogenase/reductase 3target
Vitamin AAldehyde dehydrogenase family 1 member A3target
Vitamin AAll-trans-retinol 13,14-reductasetarget
Vitamin ARetinol dehydrogenase 11target
Vitamin ADehydrogenase/reductase SDR family member 4target
Vitamin ARetinol dehydrogenase 14target
Vitamin ARetinol dehydrogenase 8target
Vitamin ACytochrome P450 26A1enzyme
Vitamin AApolipoprotein Dtarget
Vitamin AProstaglandin-H2 D-isomerasetarget
Vitamin ASerum albumincarrier
Vitamin ARetinaldehyde-binding protein 1carrier
Vitamin ARetinol-binding protein 3carrier
Vitamin ARetinol-binding protein 1carrier
Vitamin AReceptor for retinol uptake STRA6transporter
SapropterinPhenylalanine-4-hydroxylasetarget
SapropterinNitric oxide synthase, endothelialtarget
SapropterinTyrosine 3-monooxygenasetarget
SapropterinTryptophan 5-hydroxylase 1target
SapropterinProstaglandin G/H synthase 2enzyme
TreprostinilP2Y purinoceptor 12target
TreprostinilPeroxisome proliferator-activated receptor deltatarget
TreprostinilProstacyclin receptortarget
TreprostinilCytochrome P450 2C9enzyme
Carboprost tromethamineProstaglandin E2 receptor EP1 subtypetarget
AcitretinRetinoic acid receptor alphatarget
AcitretinRetinoic acid receptor RXR-betatarget
AcitretinRetinoic acid receptor gammatarget
AcitretinRetinoic acid receptor betatarget
AcitretinRetinoic acid receptor RXR-gammatarget
AcitretinRetinoic acid receptor RXR-alphatarget
AcitretinSerum albumincarrier
AcitretinRetinol-binding protein 1target
AcitretinRetinoic acid receptor RXRtarget
AlitretinoinRetinoic acid receptor alphatarget
AlitretinoinRetinoic acid receptor RXR-betatarget
AlitretinoinRetinoic acid receptor gammatarget
AlitretinoinRetinoic acid receptor betatarget
AlitretinoinRetinoic acid receptor RXR-gammatarget
AlitretinoinRetinoic acid receptor RXR-alphatarget
AlitretinoinCellular retinoic acid-binding protein 2carrier
AlitretinoinCellular retinoic acid-binding protein 1carrier
AlitretinoinP-glycoprotein 1transporter
AlitretinoinInsulin-like growth factor-binding protein 3target
AlitretinoinPregnancy-specific beta-1-glycoprotein 5target
AlitretinoinCytochrome P450 26C1target
MethotrexateDihydrofolate reductasetarget
MethotrexateAldehyde oxidaseenzyme
MethotrexateMethylenetetrahydrofolate reductaseenzyme
MethotrexateSerum albumincarrier
MethotrexateCanalicular multispecific organic anion transporter 2transporter
MethotrexateMultidrug resistance-associated protein 4transporter
MethotrexateMultidrug resistance-associated protein 1transporter
MethotrexateSolute carrier family 22 member 6transporter
MethotrexateMultidrug resistance-associated protein 7transporter
MethotrexateSolute carrier family 22 member 8transporter
MethotrexateCanalicular multispecific organic anion transporter 1transporter
MethotrexateP-glycoprotein 1transporter
MethotrexateSolute carrier organic anion transporter family member 1A2transporter
MethotrexateMonocarboxylate transporter 1transporter
MethotrexateATP-binding cassette sub-family C member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1B3transporter
MethotrexateSolute carrier family 22 member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1C1transporter
MethotrexateSolute carrier organic anion transporter family member 3A1transporter
MethotrexateATP-binding cassette sub-family G member 2transporter
MethotrexateSolute carrier family 22 member 7transporter
MethotrexateSolute carrier organic anion transporter family member 1B1transporter
Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
MethotrexateProton-coupled folate transportertransporter
MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
MethotrexateGamma-glutamyl hydrolaseenzyme
MethotrexateDihydrofolate reductaseenzyme
MethotrexateThymidylate synthaseenzyme
MethotrexateBifunctional purine biosynthesis protein PURHenzyme
MethotrexateSolute carrier organic anion transporter family member 4C1transporter
MethotrexateFolate transporter 1transporter
MethotrexateFolate receptor alphatransporter
MethotrexateCytochrome P450 3A4enzyme
MethotrexateThymidylate synthasetarget
MethotrexateBifunctional purine biosynthesis protein PURHtarget
MethotrexateFolate receptor betatransporter
MethotrexateSolute carrier family 15 member 1transporter
MethotrexateProton-coupled amino acid transporter 1transporter
AdenosineAdenosine receptor A3target
AdenosineAdenosine deaminaseenzyme
AdenosineAdenosine kinaseenzyme
AdenosineAdenosine receptor A1target
AdenosineAdenosine receptor A2atarget
AdenosineAdenosine receptor A2btarget
AdenosineSolute carrier family 28 member 3transporter
LeucovorinSolute carrier family 22 member 8transporter
LatanoprostProstaglandin F2-alpha receptortarget
LatanoprostSolute carrier organic anion transporter family member 2A1transporter
LatanoprostSolute carrier family 22 member 6transporter
LatanoprostSolute carrier family 22 member 8transporter
LatanoprostCorneal esterasesenzyme
Porfimer sodiumLow-density lipoprotein receptortarget
Porfimer sodiumHigh affinity immunoglobulin gamma Fc receptor Itarget
TretinoinRetinoic acid receptor gammatarget
TretinoinRetinoic acid receptor RXR-betatarget
TretinoinRetinal dehydrogenase 1target
TretinoinRetinoic acid-induced protein 3target
TretinoinRetinoic acid receptor RXR-gammatarget
TretinoinRetinal dehydrogenase 2target
TretinoinRetinoic acid receptor responder protein 1target
TretinoinCytochrome P450 2C8enzyme
TretinoinCellular retinoic acid-binding protein 1transporter
TretinoinCellular retinoic acid-binding protein 2transporter
TretinoinCytochrome P450 2B6enzyme
TretinoinCytochrome P450 3A4enzyme
TretinoinCytochrome P450 3A5enzyme
TretinoinCytochrome P450 2A6enzyme
TretinoinCytochrome P450 3A7enzyme
TretinoinCytochrome P450 2C18enzyme
TretinoinCytochrome P450 2C9enzyme
TretinoinCytochrome P450 4A11enzyme
TretinoinCytochrome P450 1A1enzyme
TretinoinRetinoic acid receptor alphatarget
TretinoinRetinoic acid receptor betatarget
TretinoinLipocalin-1target
TretinoinOdorant-binding protein 2atarget
TretinoinRetinol-binding protein 4target
TretinoinSerum albumincarrier
Tretinoin[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrialtarget
TretinoinRetinoic acid receptor RXR-alphatarget
TretinoinCytochrome P450 26A1target
TretinoinCytochrome P450 26B1target
TretinoinCytochrome P450 26C1target
TretinoinHematopoietic prostaglandin D synthasetarget
AlprostadilProstaglandin E2 receptor EP2 subtypetarget
AlprostadilProstaglandin E2 receptor EP1 subtypetarget
AlprostadilMultidrug resistance-associated protein 5transporter
AlprostadilSolute carrier organic anion transporter family member 2B1transporter
AlprostadilSolute carrier organic anion transporter family member 3A1transporter
AlprostadilMultidrug resistance-associated protein 4transporter
AlprostadilSolute carrier organic anion transporter family member 2A1transporter
AlprostadilProstaglandin D2 receptor 2target
AlprostadilSolute carrier family 22 member 6transporter
BimatoprostProstaglandin F2-alpha receptortarget
BimatoprostProstaglandin E2 receptor EP1 subtypetarget
BimatoprostProstaglandin E2 receptor EP3 subtypetarget
BimatoprostCytochrome P450 3A4enzyme
BimatoprostCytochrome P450 3A5enzyme
DinoprostoneProstaglandin E2 receptor EP2 subtypetarget
DinoprostoneProstaglandin E2 receptor EP1 subtypetarget
DinoprostoneProstaglandin E2 receptor EP4 subtypetarget
DinoprostoneProstaglandin E2 receptor EP3 subtypetarget
DinoprostoneSolute carrier family 22 member 2transporter
DinoprostoneMultidrug resistance-associated protein 5transporter
DinoprostoneSolute carrier family 22 member 6transporter
DinoprostoneSolute carrier family 22 member 8transporter
DinoprostoneSolute carrier family 22 member 11transporter
DinoprostoneSolute carrier family 22 member 7transporter
DinoprostoneMultidrug resistance-associated protein 4transporter
DinoprostoneSolute carrier organic anion transporter family member 2B1transporter
DinoprostoneSolute carrier organic anion transporter family member 1A2transporter
DinoprostoneOrganic solute transporter subunit alphatransporter
DinoprostoneOrganic solute transporter subunit betatransporter
DinoprostoneSolute carrier organic anion transporter family member 2A1transporter
DinoprostoneSolute carrier organic anion transporter family member 4A1transporter
DinoprostoneSolute carrier organic anion transporter family member 1C1transporter
DinoprostoneSolute carrier organic anion transporter family member 3A1transporter
DinoprostoneSolute carrier organic anion transporter family member 1B1transporter
DinoprostoneProstaglandin D2 receptor 2target
EtretinateRetinoic acid receptor alphatarget
EtretinateRetinoic acid receptor RXR-betatarget
EtretinateRetinoic acid receptor gammatarget
EtretinateRetinoic acid receptor betatarget
EtretinateRetinoic acid receptor RXR-gammatarget
EtretinateRetinoic acid receptor RXR-alphatarget
EtretinateCellular retinoic acid-binding protein 1carrier
EtretinateCytochrome P450 19A1enzyme
MisoprostolProstaglandin E2 receptor EP2 subtypetarget
MisoprostolProstaglandin E2 receptor EP3 subtypetarget
MisoprostolProstaglandin E2 receptor EP4 subtypetarget
MisoprostolProstaglandin E2 receptor EP1 subtypetarget
IsotretinoinRetinoic acid receptor alphatarget
IsotretinoinSerum albumincarrier
IsotretinoinRetinoic acid receptor gammatarget
IsotretinoinCytochrome P450 3A4enzyme
LubiprostoneChloride channel protein 2target
LubiprostoneCarbonyl reductase [NADPH] 1enzyme
IloprostProstacyclin receptortarget
IloprostTissue-type plasminogen activatortarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
IloprostSolute carrier organic anion transporter family member 2B1transporter
IloprostSolute carrier organic anion transporter family member 2A1transporter
IloprostSolute carrier organic anion transporter family member 3A1transporter
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
IloprostProstaglandin E2 receptor EP1 subtypetarget
IloprostProstaglandin D2 receptor 2target
Dinoprost tromethamineProstacyclin receptortarget
Dinoprost tromethamineProstaglandin F2-alpha receptortarget
Dinoprost tromethamineSolute carrier family 22 member 2transporter
Dinoprost tromethamineSolute carrier family 22 member 6transporter
Dinoprost tromethamineSolute carrier family 22 member 7transporter
Dinoprost tromethamineSolute carrier family 22 member 8transporter
Dinoprost tromethamineSolute carrier family 22 member 11transporter
Dinoprost tromethamineSolute carrier organic anion transporter family member 2A1transporter
Dinoprost tromethamineSolute carrier organic anion transporter family member 3A1transporter
EpoprostenolP2Y purinoceptor 12target
EpoprostenolProstacyclin receptortarget
EpoprostenolProstacyclin synthasetarget
ExenatideGlucagon-like peptide 1 receptortarget
ExenatideSerum albumincarrier
ExenatideDipeptidyl peptidase 4enzyme
MecaserminInsulin-like growth factor 1 receptortarget
MecaserminInsulin-like growth factor-binding protein 3target
MecaserminInsulin receptortarget
MecaserminCation-independent mannose-6-phosphate receptortarget
MecaserminInsulin-like growth factor-binding protein 3carrier
MecaserminInsulin-like growth factor-binding protein complex acid labile subunitcarrier
MecaserminInsulin-like growth factor-binding protein 1carrier
MecaserminInsulin-like growth factor-binding protein 2carrier
MecaserminInsulin-like growth factor-binding protein 4carrier
MecaserminInsulin-like growth factor-binding protein 5carrier
MecaserminInsulin-like growth factor-binding protein 6carrier
CalciumProtein S100-Btarget
CalciumCalpastatintarget
CalciumCartilage oligomeric matrix proteintarget
CalciumCalmodulintarget
CalciumSpectrin beta chain, non-erythrocytic 1target
CalciumVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
CalciumTroponin C, skeletal muscletarget
CalciumTroponin C, slow skeletal and cardiac musclestarget
CalciumCalcium-transporting ATPase type 2C member 1target
CalciumAmiloride-sensitive amine oxidase [copper-containing]target
CalciumProtein S100-A13target
CalciumAlkaline phosphatase, placental typetarget
CalciumProtein S100-A8target
CalciumProtein S100-A9target
CalciumProtein S100-A2target
CalciumCeruloplasmintarget
CalciumBone morphogenetic protein 4target
CalciumMatrix Gla proteintarget
CalciumProtocadherin-19target
CalciumProgrammed cell death protein 6target
BufotenineAmine oxidase [flavin-containing] Aenzyme
Bacteriochlorophyll ABacteriochlorophyll a proteintarget
Bacteriochlorophyll ABacteriochlorophyll a proteintarget
N-MethylmesoporphyrinFerrochelatasetarget
6-Hydroxymethyl-7,8-Dihydropterin2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinasetarget
6-Hydroxymethyl-7,8-DihydropterinDihydroneopterin aldolasetarget
Chlorophyll ABeta-lactamase 2target
Platelet Activating FactorGanglioside GM2 activatortarget
Platelet Activating FactorP-glycoprotein 1transporter
Platelet Activating FactorPlatelet-activating factor receptortarget
ProtoporphyrinFerritin light chaintarget
Hydrogenobyrinic acidPrecorrin-8X methylmutasetarget
SirohemeSulfite reductase [NADPH] hemoprotein beta-componenttarget
Arotinoid acidRetinoic acid receptor betatarget
Flavin adenine dinucleotidep-hydroxybenzoate hydroxylasetarget
Flavin adenine dinucleotideNitric oxide synthase, braintarget
Flavin adenine dinucleotideNAD(P)H dehydrogenase [quinone] 1target
Flavin adenine dinucleotidep-hydroxybenzoate hydroxylasetarget
Flavin adenine dinucleotideFumarate reductase flavoprotein subunittarget
Flavin adenine dinucleotideERO1-like protein betatarget
Flavin adenine dinucleotideGlutathione reductase, mitochondrialtarget
Flavin adenine dinucleotideNADPH-ferredoxin reductase FprAtarget
Flavin adenine dinucleotideNADH-cytochrome b5 reductase 3target
Flavin adenine dinucleotideCholesterol oxidasetarget
Flavin adenine dinucleotideThymidylate synthase ThyXtarget
Flavin adenine dinucleotidePyruvate oxidasetarget
Flavin adenine dinucleotideGlutathione reductasetarget
Flavin adenine dinucleotideMonomeric sarcosine oxidasetarget
Flavin adenine dinucleotideTrypanothione reductasetarget
Flavin adenine dinucleotideRibosyldihydronicotinamide dehydrogenase [quinone]target
Flavin adenine dinucleotideIsovaleryl-CoA dehydrogenase, mitochondrialtarget
Flavin adenine dinucleotideXanthine dehydrogenase/oxidasetarget
Flavin adenine dinucleotideCholesterol oxidasetarget
Flavin adenine dinucleotideDihydropyrimidine dehydrogenase [NADP(+)]target
Flavin adenine dinucleotideD-lactate dehydrogenasetarget
Flavin adenine dinucleotideThioredoxin reductase 1, cytoplasmictarget
Flavin adenine dinucleotideIsobutyryl-CoA dehydrogenase, mitochondrialtarget
Flavin adenine dinucleotideApoptosis-inducing factor 1, mitochondrialtarget
Flavin adenine dinucleotideUDP-galactopyranose mutasetarget
Flavin adenine dinucleotideFlavohemoproteintarget
Flavin adenine dinucleotideGlycine oxidasetarget
Flavin adenine dinucleotideNADPH--cytochrome P450 reductasetarget
Flavin adenine dinucleotideGlutaryl-CoA dehydrogenase, mitochondrialtarget
Flavin adenine dinucleotideMedium-chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Flavin adenine dinucleotideD-amino-acid oxidasetarget
Flavin adenine dinucleotideBifunctional protein PutAtarget
Flavin adenine dinucleotideDeoxyribodipyrimidine photo-lyasetarget
Flavin adenine dinucleotideAmine oxidase [flavin-containing] Atarget
Flavin adenine dinucleotideShort-chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Flavin adenine dinucleotideL-amino-acid oxidasetarget
Flavin adenine dinucleotide2,4-dienoyl-CoA reductase [NADPH]target
Flavin adenine dinucleotide2-oxopropyl-CoM reductase, carboxylatingtarget
Flavin adenine dinucleotideFumarate reductase flavoprotein subunittarget
Flavin adenine dinucleotideThioredoxin reductasetarget
Flavin adenine dinucleotide5,10-methylenetetrahydrofolate reductasetarget
Flavin adenine dinucleotideN,N-dimethylglycine oxidasetarget
Flavin adenine dinucleotideNADH peroxidasetarget
Flavin adenine dinucleotideFerredoxin--NADP reductasetarget
Flavin adenine dinucleotideSulfite reductase [NADPH] flavoprotein alpha-componenttarget
Flavin adenine dinucleotideFerredoxin--NADP reductasetarget
Flavin adenine dinucleotideAcyl-CoA dehydrogenase, short-chain specifictarget
Flavin adenine dinucleotideFerredoxin reductasetarget
Flavin adenine dinucleotideDihydrolipoyl dehydrogenasetarget
Flavin adenine dinucleotideAmine oxidase, flavin-containing proteintarget
Flavin adenine dinucleotideDeoxyribodipyrimidine photo-lyasetarget
Flavin adenine dinucleotideDeoxyribodipyrimidine photo-lyasetarget
Flavin adenine dinucleotideL-aspartate oxidasetarget
Flavin adenine dinucleotideCryptochrome DASHtarget
Flavin adenine dinucleotideDihydrolipoyl dehydrogenase, mitochondrialtarget
Flavin adenine dinucleotideFumarate reductase flavoprotein subunittarget
Flavin adenine dinucleotideNADH-cytochrome b5 reductase 1target
Flavin adenine dinucleotideOxidoreductasetarget
Flavin adenine dinucleotideAmine oxidase [flavin-containing] Btarget
Flavin adenine dinucleotideNADPH:adrenodoxin oxidoreductase, mitochondrialtarget
Flavin adenine dinucleotidePeroxisomal acyl-coenzyme A oxidase 1target
Flavin adenine dinucleotideUDP-N-acetylenolpyruvoylglucosamine reductasetarget
Flavin adenine dinucleotideFAD-linked sulfhydryl oxidase ALRtarget
Flavin adenine dinucleotideUDP-N-acetylenolpyruvoylglucosamine reductasetarget
Flavin adenine dinucleotideFlavohemoproteintarget
Flavin adenine dinucleotidePhenol 2-hydroxylase component Btarget
Flavin adenine dinucleotideMethylenetetrahydrofolate reductasetarget
Flavin adenine dinucleotidePutidaredoxin reductasetarget
Flavin adenine dinucleotideNAD(P)H dehydrogenase (quinone)target
Flavin adenine dinucleotideUDP-galactopyranose mutasetarget
Flavin adenine dinucleotide4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerasetarget
Flavin adenine dinucleotide4-cresol dehydrogenase [hydroxylating] flavoprotein subunittarget
Flavin adenine dinucleotideAlkyl hydroperoxide reductase subunit Ftarget
Flavin adenine dinucleotideOuter membrane protein p64k or PM-6target
Flavin adenine dinucleotideGlutathione reductasetarget
Flavin adenine dinucleotidePhenylacetone monooxygenasetarget
Flavin adenine dinucleotideBenzoate 1,2-dioxygenase electron transfer componenttarget
Flavin adenine dinucleotidePutative acyl-CoA dehydrogenasetarget
Flavin adenine dinucleotideFkbItarget
Flavin adenine dinucleotideDihydrolipoyl dehydrogenasetarget
Flavin adenine dinucleotideDihydrolipoyl dehydrogenasetarget
Flavin adenine dinucleotideAlkyl hydroperoxide reductase subunit Ftarget
Flavin adenine dinucleotideFerredoxin--NADP reductasetarget
Flavin adenine dinucleotideFerredoxin--NADP reductasetarget
Flavin adenine dinucleotideMersacidin decarboxylasetarget
Flavin adenine dinucleotideAmine oxidase [flavin-containing] Benzyme
Flavin adenine dinucleotideNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrialtarget
6-Hydroxymethylpterin2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinasetarget
Ferroheme CNitrite reductasetarget
Ferroheme CHigh-molecular-weight cytochrome ctarget
Ferroheme CCytochrome c''target
Ferroheme CQuinohemoprotein ethanol dehydrogenase type-1target
Ferroheme CNitrite reductasetarget
Ferroheme CCytochrome c4target
Ferroheme CCytochrome ctarget
Ferroheme CCytochrome c-552target
Ferroheme CCytochrome c2target
Ferroheme CCytochrome c-550target
Ferroheme CCytochrome c-552target
Ferroheme CCytochrome c-551target
Ferroheme CCytochrome c3target
Ferroheme CSplit-Soret cytochrome ctarget
Ferroheme CGroup 1 truncated hemoglobin GlbNtarget
Ferroheme CCytochrome c-553target
Ferroheme CCytochrome P450 2C9target
Ferroheme CNine-heme cytochrome ctarget
Ferroheme CCytochrome c3, 13 kDatarget
Ferroheme CCytochrome c551 peroxidasetarget
Ferroheme CCytochrome c3target
Ferroheme CCytochrome c'target
Ferroheme CCytochrome c3target
Heme DNitrite reductasetarget
Heme DNitrite reductasetarget
Coproporphyrin IUroporphyrinogen decarboxylasetarget
Prostaglandin G2Prostaglandin G/H synthase 2target
BiopterinSepiapterin reductasetarget
Biopterin6-pyruvoyl tetrahydrobiopterin synthasetarget
BiopterinDihydrofolate reductasetarget
Pteroic acidDihydropteroate synthasetarget
LumichromeFlavin reductase (NADPH)target
LumichromeRiboflavin biosynthesis protein RibFtarget
L-erythro-7,8-dihydrobiopterinPhenylalanine-4-hydroxylasetarget
L-erythro-7,8-dihydrobiopterinPteridine reductase 1target
L-erythro-7,8-dihydrobiopterinNitric oxide synthase, inducibletarget
L-erythro-7,8-dihydrobiopterinTyrosine 3-monooxygenasetarget
L-erythro-7,8-dihydrobiopterinPterin-4-alpha-carbinolamine dehydratasetarget
L-erythro-7,8-dihydrobiopterinDihydroneopterin aldolasetarget
7,8-DihydroneopterinDihydroneopterin aldolasetarget
Coproporphyrinogen IIIUroporphyrinogen decarboxylasetarget
Arachidonic AcidProstaglandin G/H synthase 1target
Arachidonic AcidSerum albumincarrier
Arachidonic AcidFatty acid-binding protein, adipocytecarrier
Arachidonic Acid14 kDa fatty acid-binding proteintarget
Arachidonic AcidFatty acid-binding protein, intestinalcarrier
Arachidonic AcidCytochrome P450 2C9enzyme
Arachidonic AcidSolute carrier organic anion transporter family member 2A1transporter
Arachidonic AcidPeroxisome proliferator-activated receptor alphatarget
Arachidonic AcidBile acid receptortarget
Arachidonic AcidRetinoic acid receptor RXR-alphatarget
N-acetylhistamineGlutaminyl-peptide cyclotransferasetarget
VerdohemeHeme oxygenase 1target
StannsoporfinHeme oxygenase 1target
StannsoporfinHeme oxygenase 2target
DesmoteplasePlasminogentarget
EritoranToll-like receptor 4target
FenretinideRetinol-binding protein 4carrier
AbaloparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget
LeptinLeptin receptortarget
AncrodFibrinogen alpha chaintarget
VintafolideFolate receptor betatarget
VintafolideFolate receptor gammatarget
VintafolideFolate receptor alphatarget
BeraprostProstacyclin receptortarget
BeraprostCytochrome P450 2C8enzyme
TetrodotoxinSodium channel protein type 1 subunit alphatarget
TetrodotoxinSodium channel protein type 2 subunit alphatarget
TetrodotoxinSodium channel protein type 3 subunit alphatarget
TetrodotoxinSodium channel protein type 8 subunit alphatarget
Interferon alfaInterferon alpha/beta receptor 1target
Interferon alfaCytochrome P450 1A2enzyme
keyhole limpet hemocyaninInterleukin-2target
Cintredekin BesudotoxInterleukin-13target
RomiplostimThrombopoietin receptortarget
HistamineHistamine H1 receptortarget
HistamineHistamine H2 receptortarget
HistamineHistamine H3 receptortarget
HistamineHistamine N-methyltransferaseenzyme
HistamineSolute carrier family 22 member 2transporter
HistamineSolute carrier family 22 member 1transporter
HistamineSolute carrier family 22 member 3transporter
HistamineSolute carrier family 22 member 5transporter
HistamineHistamine H4 receptortarget
HistamineSynaptic vesicular amine transportertarget
Albinterferon Alfa-2BCytochrome P450 1A2enzyme
TifuvirtidePlasma serine protease inhibitortarget
Motexafin gadoliniumThioredoxin reductase 1, cytoplasmictarget
Motexafin gadoliniumThioredoxin reductase 2, mitochondrialtarget
Motexafin gadoliniumRibonucleoside-diphosphate reductase subunit M2target
CobiprostoneChloride channel protein 2target
PRO-542Free fatty acid receptor 4target
CTCE-0214Stromal cell-derived factor 1target
IRL-1620Endothelin B receptortarget
IcatibantB2 bradykinin receptortarget
IcatibantAminopeptidase Ntarget
LanoteplaseUrokinase plasminogen activator surface receptortarget
LanoteplaseFibrinogen alpha chaintarget
LanoteplaseKallikrein-1target
LanoteplaseLaminin subunit alpha-5target
LanoteplaseCoagulation factor Xtarget
LanoteplaseFibronectintarget
LanoteplasePlasminogen activator inhibitor 2target
LanoteplaseTetranectintarget
LanoteplaseKeratin, type II cytoskeletal 8target
LanoteplaseAnnexin A2target
LanoteplaseLaminin subunit beta-1target
LanoteplaseLaminin subunit gamma-1target
LanoteplaseLaminin subunit alpha-1target
LanoteplaseCalreticulintarget
LanoteplaseCalnexintarget
LanoteplaseProlow-density lipoprotein receptor-related protein 1target
LanoteplaseLaminin subunit alpha-3target
Endostatin72 kDa type IV collagenasetarget
EndostatinMatrix metalloproteinase-9target
EndostatinCollagenase 3target
EndostatinFocal adhesion kinase 1target
EndostatinE-selectintarget
EndostatinCytochrome P450 19A1enzyme
E5531Toll-like receptor 4target
ThrombopoietinThrombopoietin receptortarget
AstaxanthinNF-kappa-B inhibitor alphatarget
LabradimilB2 bradykinin receptortarget
Beta caroteneBeta,beta-carotene 15,15'-dioxygenaseenzyme
Beta caroteneFree radicalstarget
Beta caroteneVery low-density lipoprotein receptorcarrier
Beta caroteneRetinol-binding protein 1carrier
Beta caroteneRetinol-binding protein 2carrier
Beta caroteneRetinol-binding protein 3carrier
Beta caroteneRetinol-binding protein 4carrier
Beta caroteneRetinol-binding protein 5carrier
PralatrexateFolylpolyglutamate synthase, mitochondrialenzyme
PralatrexateDihydrofolate reductasetarget
PralatrexateThymidylate synthasetarget
PralatrexateFolate transporter 1transporter
PralatrexateCanalicular multispecific organic anion transporter 1transporter
PralatrexateATP-binding cassette sub-family G member 2transporter
3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acidRetinoic acid receptor gammatarget
Ro 12-7310Cellular retinoic acid-binding protein 2carrier
TafluprostProstaglandin F2-alpha receptortarget
TafluprostProstaglandin G/H synthase 2enzyme
SerotoninSolute carrier family 22 member 2transporter
SerotoninSodium-dependent serotonin transportertarget
Serotonin5-hydroxytryptamine receptor 2Atarget
Serotonin5-hydroxytryptamine receptor 3Atarget
Serotonin5-hydroxytryptamine receptor 3Btarget
SerotoninSynaptic vesicular amine transportertarget
Leukotriene C4Solute carrier organic anion transporter family member 1B1transporter
Leukotriene C4Solute carrier organic anion transporter family member 1B3transporter
Leukotriene C4Cysteinyl leukotriene receptor 1target
Leukotriene C4Cysteinyl leukotriene receptor 2target
Leukotriene C4Multidrug resistance-associated protein 1target
AminopterinProton-coupled folate transportertransporter
AminopterinDihydrofolate reductaseenzyme
GemeprostProstaglandin E2 receptor EP2 subtypetarget
GemeprostProstaglandin E2 receptor EP3 subtypetarget
MetreleptinLeptin receptortarget
AncestimMast/stem cell growth factor receptor Kittarget
Methoxy polyethylene glycol-epoetin betaErythropoietin receptortarget
Turoctocog alfaCoagulation factor IXtarget
Turoctocog alfaCoagulation factor Xtarget
Turoctocog alfaProthrombintarget
Peginterferon beta-1aCytochrome P450 1A2enzyme
LimaprostProstaglandin E2 receptor EP1 subtypetarget
LimaprostProstaglandin E2 receptor EP2 subtypetarget
LimaprostProstaglandin E2 receptor EP3 subtypetarget
LimaprostProstaglandin E2 receptor EP4 subtypetarget
Omega-3-acid ethyl estersSterol O-acyltransferase 1enzyme
Omega-3-acid ethyl estersSterol regulatory element-binding protein 1target
ThrombinProteinase-activated receptor 1target
ThrombinProteinase-activated receptor 4target
ThrombinCoagulation factor XItarget
ThrombinCoagulation factor XIII A chaintarget
ThrombinCoagulation factor XIII B chaintarget
ThrombinFibrinogen alpha chaintarget
ThrombinFibrinogen beta chaintarget
ThrombinFibrinogen gamma chaintarget
ThrombinCoagulation factor Vtarget
ThrombinCoagulation factor VIIItarget
ProthrombinFibrinogen alpha chaintarget
ProthrombinFibrinogen beta chaintarget
ProthrombinCoagulation factor XIII A chaintarget
ProthrombinCarboxypeptidase B2target
ProthrombinCoagulation factor Xenzyme
Protein CCoagulation factor Vtarget
Protein CCoagulation factor VIIItarget
ZeranolEstrogen receptor alphatarget
ZeranolSex hormone-binding globulintarget
LevoleucovorinSerine hydroxymethyltransferasetarget
Antithrombin III humanAntithrombin-IIItarget
Tuberculin purified protein derivativeToll-like receptor 2target
Dibotermin alfaBone morphogenetic protein receptor type-1Atarget
Dibotermin alfaBone morphogenetic protein receptor type-2target
Latanoprostene bunodProstaglandin F2-alpha receptortarget
Latanoprostene bunodSolute carrier organic anion transporter family member 2B1transporter
DinitrochlorobenzeneMethylated-DNA--protein-cysteine methyltransferasetarget
DinitrochlorobenzeneGlutathione S-transferase Ptarget
Angiotensin IIType-1 angiotensin II receptortarget
Leukotriene D4Cysteinyl leukotriene receptor 1target
Leukotriene D4Cysteinyl leukotriene receptor 2target
EpofolateCytochrome P450 3A4enzyme
MuscimolGamma-aminobutyric acid receptor subunit alpha-1target
MuscimolGamma-aminobutyric acid receptor subunit beta-3target
MuscimolGamma-aminobutyric acid receptor subunit gamma-2target
LometrexolDihydrofolate reductasetarget
DinoprostProstaglandin D2 receptor 2target
Leukotriene B4Leukotriene B4 receptor 1target
Leukotriene B4Leukotriene B4 receptor 2target
Leukotriene B4Peroxisome proliferator-activated receptor alphatarget
Von Willebrand Factor HumanCoagulation factor VIIItarget
Von Willebrand Factor HumanCollagen alpha-1(I) chaintarget
Von Willebrand Factor HumanA disintegrin and metalloproteinase with thrombospondin motifs 13enzyme
LenograstimGranulocyte colony-stimulating factor receptortarget
Protein S humanCoagulation factor Vtarget
Protein S humanCoagulation factor Xtarget
Protein S humanVitamin K-dependent protein Ctarget
Coagulation factor VII humanTissue factortarget
Coagulation factor VII humanCoagulation factor Xtarget
Coagulation factor VII humanCoagulation factor IXtarget
Antihemophilic factor humanCoagulation factor IXtarget
Antihemophilic factor humanCoagulation factor Xtarget
Antihemophilic factor humanVitamin K-dependent protein Cenzyme
LipegfilgrastimGranulocyte colony-stimulating factor receptortarget
Nonacog beta pegolCoagulation factor VIItarget
Nonacog beta pegolCoagulation factor VIIItarget
Nonacog beta pegolCoagulation factor Xtarget
Moroctocog alfaCoagulation factor Xtarget
Moroctocog alfaPhytanoyl-CoA dioxygenase, peroxisomaltarget
Moroctocog alfaCoagulation factor IXtarget
Moroctocog alfaAsialoglycoprotein receptor 2target
Moroctocog alfa78 kDa glucose-regulated proteintarget
Moroctocog alfaCalreticulintarget
Moroctocog alfaCalnexintarget
Moroctocog alfaProtein ERGIC-53target
Moroctocog alfaProlow-density lipoprotein receptor-related protein 1target
Moroctocog alfaMultiple coagulation factor deficiency protein 2target
Moroctocog alfavon Willebrand factortarget
Moroctocog alfaProthrombinenzyme
Moroctocog alfaVitamin K-dependent protein Cenzyme
Andexanet alfaTissue factor pathway inhibitortarget
Antihemophilic Factor (Recombinant), PEGylatedvon Willebrand factortarget
Antihemophilic Factor (Recombinant), PEGylatedvon Willebrand factorcarrier
LuteinSerum albumincarrier
Prostaglandin D2Aldo-keto reductase family 1 member C3target
Prostaglandin D2Solute carrier organic anion transporter family member 2A1transporter
Prostaglandin D2Prostaglandin D2 receptor 2target
Flavin mononucleotideFlavin reductase (NADPH)target
Flavin mononucleotideHydroxyacid oxidase 1target
Flavin mononucleotidePyridoxine-5'-phosphate oxidasetarget
Flavin mononucleotideMajor NAD(P)H-flavin oxidoreductasetarget
Flavin mononucleotideRiboflavin kinasetarget
Flavin mononucleotideOxygen-insensitive NADPH nitroreductasetarget
Flavin mononucleotideNitric oxide synthase, braintarget
Flavin mononucleotideDihydroorotate dehydrogenase (quinone)target
Flavin mononucleotideDihydropyrimidine dehydrogenase [NADP(+)]target
Flavin mononucleotideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
Flavin mononucleotideFlavodoxintarget
Flavin mononucleotideOxygen-insensitive NAD(P)H nitroreductasetarget
Flavin mononucleotideChorismate synthasetarget
Flavin mononucleotide2,4-dienoyl-CoA reductase [NADPH]target
Flavin mononucleotideDihydroorotate dehydrogenase A (fumarate)target
Flavin mononucleotidePyridoxine/pyridoxamine 5'-phosphate oxidasetarget
Flavin mononucleotidePentaerythritol tetranitrate reductasetarget
Flavin mononucleotideFMN-dependent NADH-azoreductasetarget
Flavin mononucleotideEpidermin decarboxylasetarget
Flavin mononucleotideFMN-dependent NADH-azoreductasetarget
Flavin mononucleotideChorismate synthasetarget
Flavin mononucleotideFlavodoxintarget
Flavin mononucleotideFlavodoxintarget
Flavin mononucleotideFlavodoxintarget
Flavin mononucleotidePutative uncharacterized proteintarget
Flavin mononucleotidePutative monooxygenase MoxCtarget
Flavin mononucleotidetRNA-dihydrouridine synthasetarget
Flavin mononucleotideProtein NrdItarget
Flavin mononucleotideProbable aromatic acid decarboxylasetarget
Flavin mononucleotide(S)-mandelate dehydrogenasetarget
Flavin mononucleotideFMN-dependent NADPH-azoreductasetarget
Flavin mononucleotideFlavodoxintarget
Flavin mononucleotideSerine/threonine-protein kinase Sgk1target
Flavin mononucleotideOxygen-insensitive NAD(P)H nitroreductasetarget
Flavin mononucleotideNitric oxide reductasetarget
Flavin mononucleotideIsopentenyl-diphosphate delta-isomerasetarget
Flavin mononucleotideTrimethylamine dehydrogenasetarget
Flavin mononucleotideRubredoxin-oxygen oxidoreductasetarget
Flavin mononucleotideRiboflavin biosynthesis protein RibFtarget
Flavin mononucleotideMorphinone reductasetarget
Flavin mononucleotideNADPH-flavin oxidoreductasetarget
Flavin mononucleotideRibosomal protein S6 kinase alpha-4target
Flavin mononucleotidePhenazine biosynthesis protein PhzGtarget
Flavin mononucleotideHydroxyacid oxidase 2target
Flavin mononucleotideNAD(P)H dehydrogenase (quinone)target
Flavin mononucleotideFlavodoxin-1target
Flavin mononucleotideIsopentenyl-diphosphate delta-isomerasetarget
Flavin mononucleotideNADH dehydrogenasetarget
Flavin mononucleotideFMN-binding proteintarget
Flavin mononucleotideNitroreductase family proteintarget
Flavin mononucleotideNADPH--cytochrome P450 reductasetarget
Flavin mononucleotidePhosphopantothenoylcysteine decarboxylasetarget
Flavin mononucleotidePhzGtarget
Flavin mononucleotideFerredoxin-dependent glutamate synthase 2target
Flavin mononucleotideNADPH--cytochrome P450 reductaseenzyme
N-acetylserotoninSepiapterin reductasetarget
Turoctocog alfa pegolVitamin K-dependent protein Cenzyme
Turoctocog alfa pegolCoagulation factor Xenzyme
Turoctocog alfa pegolCoagulation factor IXtarget
Turoctocog alfa pegolCoagulation factor Xtarget
Turoctocog alfa pegolProthrombintarget
Turoctocog alfa pegolvon Willebrand factorcarrier
Methoxy arachidonyl fluorophosphonateFatty-acid amide hydrolase 1target
RegramostimGranulocyte-macrophage colony-stimulating factor receptor subunit alphatarget
RegramostimGM-CSF receptor alpha subunittarget
RegramostimCholinesteraseenzyme
Sar9, Met (O2)11-Substance PCytochrome P450 19A1enzyme
Sar9, Met (O2)11-Substance PCholinesteraseenzyme
Sar9, Met (O2)11-Substance PProstaglandin G/H synthase 2enzyme
Human interferon betaCytochrome P450 1A2enzyme
Human interferon betaInterferon alpha/beta receptor 1target
Human interferon betaSerum albumincarrier
Interferon alfa-2cCytochrome P450 1A2enzyme
BexaroteneRetinoic acid receptor RXR-betatarget
BexaroteneCytochrome P450 3A4enzyme
BexaroteneRetinoic acid receptor RXR-alphatarget
BexaroteneRetinoic acid receptor RXR-gammatarget
BexaroteneCytochrome P450 2C8enzyme
5-methyltetrahydrofolic acidAminomethyltransferase, mitochondrialtarget
5-methyltetrahydrofolic acidCanalicular multispecific organic anion transporter 1transporter
Levomefolic acidProton-coupled folate transportertransporter
Levomefolic acidFolate transporter 1transporter
Levomefolic acidMethionine synthaseenzyme
Thrombin alfaCoagulation factor VIIItarget
Thrombin alfaCoagulation factor Vtarget
Thrombin alfaFibrinogen alpha chaintarget
Thrombin alfaFibrinogen beta chaintarget
Thrombin alfaFibrinogen gamma chaintarget
Anti-inhibitor coagulant complexCoagulation factor Xtarget
Anti-inhibitor coagulant complexProthrombintarget
Anti-inhibitor coagulant complexFibrinogen alpha chaintarget
Anti-inhibitor coagulant complexFibrinogen beta chaintarget
Anti-inhibitor coagulant complexCoagulation factor XIII A chaintarget
Anti-inhibitor coagulant complexCoagulation factor Vtarget
Anti-inhibitor coagulant complexCoagulation factor VIIItarget
Anti-inhibitor coagulant complexCoagulation factor VIItarget
Anti-inhibitor coagulant complexProthrombinenzyme
Anti-inhibitor coagulant complexCoagulation factor VIIenzyme
Anti-inhibitor coagulant complexCoagulation factor VIIIenzyme
Anti-inhibitor coagulant complexCoagulation factor IXenzyme
Anti-inhibitor coagulant complexCoagulation factor Venzyme
Albutrepenonacog alfaCoagulation factor Xtarget
Albutrepenonacog alfaCoagulation factor VIIIenzyme
Axicabtagene ciloleucelB-lymphocyte antigen CD19target
Human blood group H type 1 trisaccharideHisto-blood group ABO system transferasetarget
TricetinSerine/threonine-protein kinase pim-1target
N-EthylretinamideRetinol-binding protein 4carrier