Nepidermin

Identification

Generic Name

Nepidermin

DrugBank Accession Number

DB14145

Background

Not Available

Type

Biotech

Groups

Experimental

Synonyms

• Beta-urogastrone
• Epidermal growth factor (human)
• Epidermal growth factor biosynthetic human
• Epidermal growth factor human
• H-EGF
• Human EGF
• Human epidermal growth factor
• Human urogastrone
• Nepidermin
• Nepidermina
• Népidermine
• Nepiderminum
• Recombinant human epidermal growth factor
• rhEGF
• Urogastrone

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Pharmacology

Indication

Not Available

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Associated Conditions

Indication Type	Indication	Combined Product Details	Approval Level	Age Group	Patient Characteristics	Dose Form
Treatment of	Burns first degree		••••••••••••
Treatment of	Burns second degree		••••••••••••
Treatment of	Diabetic foot ulcers (dfu)		••••••••••••			•••••••••
Treatment of	Ulcers		••••••••••••			•••••••••
Treatment of	Wounds		••••••••••••

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Associated Therapies

• Skin Care

Contraindications & Blackbox Warnings

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Pharmacodynamics

Not Available

Mechanism of action

Not Available

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism

Not Available

Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects

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Toxicity

Not Available

Pathways

Not Available

Pharmacogenomic Effects/ADRs

Not Available

Interactions

Drug Interactions

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

Not Available

Food Interactions

Not Available

Products

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International/Other Brands

Easyef / Genesoft / Kang He Su / Regen-D

Over the Counter Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End	Region	Image
EASYDEW DW EGF Derma Needle 3000 Shot	Solution	0.000045 mg/45mg	Topical	Dn Company Co.,Ltd.	2018-03-01	Not applicable
Easydew EX Repair Control Repair Control Egf	Liquid	0.0002 g/20mL	Topical	Dn Company Co.,Ltd.	2018-02-01	Not applicable
EASYDEW EX REPAIR CONTROL REPAIR CONTROL EGF 3mL	Liquid	0.03 mg/3mL	Topical	Dn Company Co.,Ltd.	2018-07-01	Not applicable

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
ARTEMES 3R Effect Hyaluronic Ampoule	Nepidermin (0.05 mg/5mL) + Adenosine (0.002 g/5mL) + Nicotinamide (0.10 g/5mL)	Liquid	Topical	Dn Company Co.,Ltd.	2019-03-01	Not applicable
Artemes 3R effect hyaluronic mask	Nepidermin (0.33 mg/33g) + Adenosine (0.01 g/33g) + Nicotinamide (0.66 g/33g)	Patch	Topical	Dn Company Co.,Ltd.	2019-03-01	Not applicable
Cosmeceutical Mask Pack	Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)	Patch	Topical	YBK Investment, INC	2013-10-21	Not applicable
Cosmeceutical Mask Pack	Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)	Patch	Topical	YBK Investment, INC	2013-10-21	2013-10-29
Dermaheal Cosmeceutical Mask Pack Plus	Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)	Patch	Topical	YBK Investment, INC	2013-10-21	Not applicable

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
ARTEMES 3R Effect Hyaluronic Ampoule	Nepidermin (0.05 mg/5mL) + Adenosine (0.002 g/5mL) + Nicotinamide (0.10 g/5mL)	Liquid	Topical	Dn Company Co.,Ltd.	2019-03-01	Not applicable
Artemes 3R effect hyaluronic mask	Nepidermin (0.33 mg/33g) + Adenosine (0.01 g/33g) + Nicotinamide (0.66 g/33g)	Patch	Topical	Dn Company Co.,Ltd.	2019-03-01	Not applicable
Cosmeceutical Mask Pack	Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)	Patch	Topical	YBK Investment, INC	2013-10-21	Not applicable
Cosmeceutical Mask Pack	Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)	Patch	Topical	YBK Investment, INC	2013-10-21	2013-10-29
Dermaheal Cosmeceutical Mask Pack Plus	Nepidermin (0.044 mg/22g) + Basic Fibroblast Growth Factor (0.044 mg/22g) + Mecasermin (0.044 mg/22g) + Palmitoyl oligopeptide (0.044 mg/22g) + Prezatide copper (0.22 mg/22g) + Thioredoxin (0.044 mg/22g)	Patch	Topical	YBK Investment, INC	2013-10-21	Not applicable

Categories

Drug Categories

• Amino Acids, Peptides, and Proteins
• Biological Factors
• EGF Family of Proteins
• Gastrointestinal Hormones
• Hormones
• Hormones, Hormone Substitutes, and Hormone Antagonists
• Intercellular Signaling Peptides and Proteins
• Peptides
• Proteins

Classification

Not classified

Affected organisms

Not Available

Chemical Identifiers

UNII

TZK30RF92W

CAS number

62253-63-8

References

General References

Not Available

External Links

RxNav

1427157

Wikipedia

Nepidermin

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count
3	Active Not Recruiting	Treatment	Diabetic Foot Ulcers (DFUs) / Epidermal Growth Factor	1
3	Completed	Treatment	Diabetic Foot Ulcer Patients With Uncontrolled Diabetes Mellitus	1
3	Unknown Status	Treatment	Stomatitis	1
2	Completed	Prevention	Oral Mucositis	1
2	Recruiting	Treatment	Breast Neoplasms	1

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Patch	Topical
Solution	Topical	0.000045 mg/45mg
Liquid	Topical
Cream	Topical
Liquid	Topical	0.0002 g/20mL
Liquid	Topical	0.03 mg/3mL
Solution	Topical
Solution	Topical	0.5 mg/ml
Spray	Topical
Solution	Intralesional	0.075 mg
Injection, powder, lyophilized, for solution	Intralesional	75 mcg
Lotion	Topical
Gel	Topical	150 mcg/g
Gel	Topical
Powder		0.075 mg/1vial

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

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Drug created at June 27, 2018 20:17 / Updated at May 04, 2022 16:30