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Displaying drugs 251 - 275 of 15294 in total
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Factor XIII A-Subunit (Recombinant) ... Coagulation Factor XIII A-Subunit (recombinant) ... Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) …
Matched Description: … Within the body, FXIII circulates as a heterotetramer composed of 2 catalytic A-subunits and 2 non-catalytic ... For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous ... for the routine prophylaxis of bleeding. …
Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI...
Approved
Matched Synonyms: … 2-Dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoat …
Matched Iupac: … 2-(dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate …
Matched Description: … Trimebutine is not a FDA-approved drug, but it is available in Canada and several other international ... It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility ... Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal …
Matched Categories: … Drugs for Functional Gastrointestinal Disorders …
Matched Products: … DEBRIDAT FOR ORAL SUSPENSION …
Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals,...
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine ... 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine ... 3-Chloroimipramine …
Matched Iupac: … (3-{14-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant ... See toxicity section below for a complete listing of side effects. ... In depressed individuals, clomipramine exerts a positive effect on mood. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Antidepressive Agents Indicated for Depression ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Oil extracted from olives . Consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic. Used as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products [FDA Label].
Approved
Matched Description: … Used as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products …
Matched Mixtures name: … aspen nutrition Omega 3-6-9 ... OLICLINOMEL N4-550 E EMULSION FOR INFUSION ... OLICLINOMEL N7-1000 E EMULSION FOR INFUSION …
Matched Products: … Intensive Treatment Bodyoil for Mommy To Be All Skin …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hong Kong/4801/2014 (H3N2) hemagglutinin antigen (MDCK cell derived, propiolactone …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Synonyms: … 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline ... N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine …
Matched Iupac: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine …
Matched Description: … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. ... Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant ... proteins in malignant cells. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Synonyms: … N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea ... 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Matched Description: … [A255852] First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular ... Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in
Matched Categories: … UGT1A9 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, filgrastim. The drug is approved for use to decrease the incidence of infection, as manifested by febrile neutropenia, in susceptible patients with with non-myeloid cancer receiving myelosuppressive anti-cancer treatment. Although the risk of developing febrile neutropenia...
Approved
Matched Description: … [A187601] The drug is approved for use to decrease the incidence of infection, as manifested by febrile ... It is typically administered via a subcutaneous injection. ... neutropenia, in susceptible patients with with non-myeloid cancer receiving myelosuppressive anti-cancer …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Pelgraz 6 mg solution for injection in a pre-filled syringe ... NUFILONG SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 6MG/0.6ML ... Pelgraz Solution for Injection in pre-filled syringe 6mg/0.6mL …
A sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine.
Approved
Illicit
Matched Synonyms: … 2-phenyl-3-methylmorpholine …
Matched Iupac: … 3-methyl-2-phenylmorpholine …
Matched Description: … A sympathomimetic drug used primarily as an appetite depressant. …
Equus caballus skin allergenic extract is used in allergenic testing.
Approved
Matched Description: … Equus caballus skin allergenic extract is used in allergenic testing. …
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched International brands: … Roferon A
Matched Description: … A type I interferon consisting of 165 amino acid residues with lysine in position 23. ... Interferon a (human leukocyte protein moiety reduced). …
Matched Products: … ROFERON-A PREFILLED SYRINGE FOR INJECTION 3 miu/0.5 ml ... Roferon-A Solution 3 Million I.U./ml ... ROFERON - A ROCHE SOLUCION INYECTABLE 3 K/U.I. …
Tagraxofusp is a CD123-directed cytotoxin. It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in Escherichia coli.[A253762, A253887, L43702] Tagraxofusp received its first global approval by the FDA on December 21, 2018...
Approved
Investigational
Matched Synonyms: … Diphtheria toxin-il-3 fusion protein targeting IL-3 receptor …
Matched Description: … It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic ... blastic plasmacytoid dendritic cell neoplasm, which is a myeloid malignancy in the dendritic cell lineage ... received its first global approval by the FDA on December 21, 2018 as the first FDA-approved treatment for
An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to estrogens. Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. It was formerly used for its weak anticonvulsant properties. (From Martindale,...
Approved
Investigational
Matched Synonyms: … 2-(p-Aminophenyl)-2-ethylglutarimide ... 3-Ethyl-3-(p-aminophenyl)-2,6-dioxopiperidine …
Matched Iupac: … 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione …
Matched Description: … It was formerly used for its weak anticonvulsant properties. ... Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. ... An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of …
Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Approved
Matched Mixtures name: … PROTROMPLEX TIM 3 ... PROTROMPLEX TIM 3 ... BERIPLEX P/N 500 POWDER FOR SOLUTION FOR INJECTION …
Matched Categories: … coagulation factor IX, II, VII and X in combination …
Matched Products: … OCTANINE F LYOPHILLISED POWDER FOR INTRAVENOUS ADMINISTRATION ... OCTANINE F ... IMMUNINE 120IU/ML Powder and solvent for solution for injection or infusion …
A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Synonyms: … 2-Carboxyphenol ... 2-Hydroxybenzoic acid …
Matched Iupac: … 2-hydroxybenzoic acid …
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically …
Matched Mixtures name: … Daily all in one ample ... Daily all in one ample ... All-In-One UTI Emergency Kit …
Matched Categories: … Non COX-2 selective NSAIDS ... Antifungals for Topical Use ... Antifungals for Dermatological Use …
Matched Products: … Hope In A Bottle ... M-A-C Radically Clear Blemish Cream ... ASD 3-in-1 …
Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage...
Approved
Investigational
Matched Synonyms: … 3,3,5-Trimethylcyclohexyl 2-hydroxybenzoate …
Matched Iupac: … 3,3,5-trimethylcyclohexyl 2-hydroxybenzoate …
Matched Description: … It is a common ingredient in many commercially available sunscreens. ... It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol …
Matched Mixtures name: … Hope In A Jar Broad Spectrum SPF 25 Sunscreen and Moisturizer for All Skin Types ... Hope In A Jar SPF 25 ... Gloves in a Bottle with SPF15 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
Approved
Investigational
Matched Synonyms: … (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine ... (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine ... 2-Methoxytrimeprazine …
Matched Iupac: … [(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]dimethylamine …
Matched Description: … A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine …
Matched Salts cas: … 1236-99-3 ... 7104-38-3
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Methotrimeprazine-2
Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 and is available in various countries including Canada and the U.S. According to the 2018 Clinical Practice...
Approved
Investigational
Matched Synonyms: … 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea ... N-{4-[β-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea …
Matched Iupac: … N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-5-methylpyrazine-2-carboxamide …
Matched Description: … to control blood sugar levels in patients with type 2 diabetes mellitus. ... , sulfonylureas are more commonly used for early-stage type 2 diabetes when there is no progressed pancreatic ... sulfonylureas, such as [tolbutamide] and [chlorpropamide], second-generation sulfonylureas contain a
Matched Categories: … Drugs Used in Diabetes …
Omidubicel is a nicotinamide-modified allogeneic hematopoietic progenitor cell therapy derived from cord blood used as an allogeneic stem cell donor source. Umbilical blood cord cells are expanded ex-vivo and nicotinamide (a form of vitamin B3) is used as an active agent in the culture system to inhibit the differentiation and...
Approved
Investigational
Matched Description: … treatment for blood cancers for whom a related or unrelated donor cannot be found due to the requirement ... and older with blood cancers planned for umbilical cord blood transplantation following a myeloablative ... [A258958] In April 2023, the FDA approved the use of omidubicel in adults and pediatric patients 12 years …
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … Compared to [pembrolizumab], a smaller proportion of patients experienced grade 3-4 adverse events (4% ... alternatives for the treatment of BCG-unresponsive NMIBC. ... [A255111] Nadofaragene firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer …
Arformoterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing. Arformoterol inhalation is used to prevent bronchoconstriction in people with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. The use of arformoterol is pending revision due to safety concerns in regards to an increased...
Approved
Investigational
Matched Iupac: … N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide …
Matched Description: … Arformoterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing. ... using long-acting beta agonists for the treatment of asthma. ... The use of arformoterol is pending revision due to safety concerns in regards to an increased risk of …
Matched Salts cas: … 200815-49-2
Matched Mixtures name: … AIRBIR 3/100 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL, 120 KPS ... AIRBIR 3/100 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL, 60 KPS ... AIRBIR 3/200 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL ,120 KAPSÜL …
Matched Categories: … Adrenergic beta-2 Receptor Agonists …
Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated with other targets in mind. Additionally, quizartinib also demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although...
Approved
Investigational
Matched Synonyms: … N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol- ... 2-yl)phenyl)urea …
Matched Iupac: … 3-(5-tert-butyl-1,2-oxazol-3-yl)-1-(4-{10-[2-(morpholin-4-yl)ethoxy]-7-thia-2,5-diazatricyclo[6.4.0.0²,⁶ …
Matched Description: … maintenance monotherapy resulted in a 22% reduction in the risk of death. ... Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug ... [L47436] The FDA approval was based on positive results from the QuANTUM-First trial for FLT3-ITD positive …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness preceding suicide.[L5596,A175462] On March 5, 2019, the nasal spray drug, esketamine, also known as Spravato (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. Esketamine is the s-enantiomer of Ketamine. Ketamine...
Approved
Investigational
Matched Synonyms: … (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone …
Matched Iupac: … (2S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one …
Matched Description: … The intranasal route of administration for this drug allows for easy administration and a fast onset ... [L5593] Esketamine may prove to be a promising treatment for patients diagnosed with major depressive ... The FDA approved ketamine (Ketalar) in 1970. …
Matched Categories: … Antidepressive Agents Indicated for Depression …
Matched Products: … Eskelan 25 mg/ml-Injektions-/Infusionslösung in Ampullen ... Eskelan 25 mg/ml-Injektionslösung in Durchstechflaschen ... Eskelan 5 mg/ml-Injektionslösung in Durchstechflaschen …
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,7 …
Matched Description: … Estradiol is a naturally occurring hormone circulating endogenously in females. ... It is commercially available in several hormone therapy products for managing conditions associated with ... [L11485,L11488,L11491, L11494,L11497,L11500,L11503] When used for oral or IM administration, estradiol …
Matched Salts cas: … 35380-71-3
Matched Mixtures name: … LAFAMME 2/2MG ... LAFAMME 2/2MG ... FEMOSTON 2/10MG …
Matched Categories: … Hormonal Contraceptives for Systemic Use ... Medications that reduce magnesium levels
Matched Products: … JUVENUM E ... VIPLEN 2 MG ... POSTMENOP 2 MG …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) hemagglutinin antigen (propiolactone inactivated …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Displaying drugs 251 - 275 of 15294 in total