Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 301 - 325 of 15294 in total
A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. Though estriol is...
Approved
Investigational
Vet approved
Matched International brands: … Synapause E
Matched Iupac: … (1R,2R,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Matched Description: … It is however available in the United States by prescription filled only by compounding pharmacies. ... A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and ... Estriol is a major urinary estrogen. …
Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Synonyms: … 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile …
Matched Iupac: … 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile …
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine ... in a BCR-ABL fusion protein. ... a breakthrough in CML management; however, emerging resistance to [imatinib] poses challenges in achieving …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals . Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … drugs used to decrease urate levels and is frequently used in the treatment of chronic gout [A36705] ... Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially ... Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules. It also binds to vitronectin (αvβ3) receptor found on platelets...
Approved
Matched Description: … Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. …
Matched Products: … ReoPro 2 mg/ml Injektionslösung oder Infusionslösung …
Dexfenfluramine, also marketed under the name Redux, is a serotoninergic anorectic drug. For a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing weight loss. However, following multiple concerns about the cardiovascular side-effects of the drug, such approval was withdrawn.
Approved
Illicit
Investigational
Withdrawn
Matched Synonyms: … (S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine …
Matched Iupac: … ethyl[(2S)-1-[3-(trifluoromethyl)phenyl]propan-2-yl]amine …
Matched Description: … For a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing ... Dexfenfluramine, also marketed under the name Redux, is a serotoninergic anorectic drug. …
Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Iupac: … ]-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl ... ]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-( ... 1H-indol-3-yl)propanamido]-4-methylpentanamide ... (2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl …
Matched Description: … Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. ... Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH) ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Salts cas: … 124508-66-3
Matched Products: … Triptofem 0,1 mg/ml Injektionslösung in einer Fertigspritze ... Decapeptyl Depot - Retardmikrokapseln und Suspensionsmittel in Einmalspritzen ... Pamorelin Powder for Suspension for Injection 3.75 mg …
Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Tocilizumab was granted FDA approval on 8 January 2010 to treat a...
Approved
Matched Description: … [L12789] It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing ... [L44483] Tocilizumab-bavi, a biosimilar drug, was approved by the FDA in September 2023.[L48385] ... Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory …
Matched Categories: … Agents reducing cytokine levels ... Biologics for Rheumatoid Arthritis Treatment ... Experimental Unapproved Treatments for COVID-19 …
Matched Products: … ACTEMRA (162 MG SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE) ... ACTEMRA 162MG/0.9ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE ... Actemra 162mg Solution for Injection in Pre-filled Syringe 162mg/0.9ml …
A cephalorsporin antibiotic that is no longer commonly used.
Approved
Matched Synonyms: … 7-(D-2-Amino-2-phenylacetamido)-3-acetoxymethyl-delta(sup3)-cephem-4-carboxylic acid ... 7-(2-D-alpha-Aminophenylacetamido)cephalosporanic acid …
Matched Iupac: … (6R,7R)-3-[(acetyloxy)methyl]-7-[(2R)-2-amino-2-phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct- ... 2-ene-2-carboxylic acid …
Matched Description: … A cephalorsporin antibiotic that is no longer commonly used. …
Matched Salts cas: … 22202-76-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology ... In order to improve drug delivery to the target organ, ranibizumab is available for intravitreal use. ... BYOOVIZ, a biosimilar of LUCENTIS, was approved by Health Canada in March 2022, making it the first and …
Matched Products: … LUCENTIS 10 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE ... LUCENTIS SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 1.65mg/0.165ml ... Lucentis 10mg/ml Solution for Injection …
Domestic dog hair is used in allergenic testing.
Approved
Matched Description: … Domestic dog hair is used in allergenic testing. …
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Description: … that contains 191 amino acid residues with a molecular weight of 22 kDa. ... [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone ... [A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults …
Matched Products: … GENOTROPIN C ... GROWTROPINAQ 16 U /2 ML INYECTABLE ... SciTropin A Solution for Injection 5 mg/1.5 ml …
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched International brands: … Dormarex 2
Matched Synonyms: … 2-(benzhydryloxy)-N,N-dimethylethylamine ... 2-diphenylmethoxy-N,N-demthylethanamine ... α-(2-dimethylaminoethoxy)diphenylmethane …
Matched Iupac: … [2-(diphenylmethoxy)ethyl]dimethylamine …
Matched Description: … Diphenhydramine has also been shown to be implicated in a number of neurotransmitter systems that affect ... As a result, diphenhydramine is being investigated for its anxiolytic and anti-depressant properties. ... Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation …
Matched Salts cas: … 7491-10-3
Matched Mixtures name: … Benylin for Children All-IN-one Cold & Fever Nightime ... Mucus Relief All in One Maximum Strength ... Benylin All-IN-one Cold and Flu Night PE Caplets …
Matched Categories: … Antihistamines for Topical Use ... Antihistamines for Systemic Use …
Matched Products: … A Health Itch Relief Gel ... Unisom C Nightime Sleep Aid Cap 50mg ... Only For SLEEP …
A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Approved
Matched Synonyms: … 5-[3-(2-carboxy-4-oxo-4H-5-chromenyloxy)-2-hydroxypropoxy]-4-oxo-4H-2-chromenecarboxylic acid …
Matched Iupac: … 5-{3-[(2-carboxy-4-oxo-4H-chromen-5-yl)oxy]-2-hydroxypropoxy}-4-oxo-4H-chromene-2-carboxylic acid …
Matched Description: … A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells ... It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Obstructive Airway Diseases ... Agents for Dermatitis, Excluding Corticosteroids …
Matched Products: … CONVER 2% ... OSMOCROM 2% ... CROMISOL 2% …
Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Description: … and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of urinary ... Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a ... critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents …
Matched Salts cas: … 60834-30-2 ... 56585-33-2
Matched Mixtures name: … EUSAPRIM E SUSPENS F ERW ... COTRIM E RATIO 480MG/5ML ... Hampiseptol Solution For Injection …
Matched Categories: … Medications that reduce magnesium levels ... MATE 2 Inhibitors ... MATE 2 Substrates ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
3,6-Diaminoacridine. Topical antiseptic used mainly in wound dressings.
Approved
Matched Description: … Topical antiseptic used mainly in wound dressings. …
Matched Mixtures name: … Kerr 100 Triple Dye Dispos-A
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions . Infliximab is produced by a recombinant cell line cultured by continuous perfusion. Tumor necrosis factor-alpha (TNF-α) is a key proinflammatory cytokine involved in...
Approved
Matched Description: … They are approved for all eligible indications of the reference product. ... In clinical trials, multiple infusions of infliximab displayed in a reduction of signs and symptoms of ... Inflectra, a first biosimilar drug product, was approved in 2016. …
Matched Categories: … Agents reducing cytokine levels ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … INFLECTRA 100MG PLV F E KO ... REMICADE 100MG PULV F E KO ... REMSIMA SOLUTION FOR SUBCUTANEOUS INJECTION 120 MG/ML IN PRE-FILLED PEN …
Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant to other osteoperosis therapies . Romosozumab prevents bone resorption and induces the formation of bone though it is associated...
Approved
Investigational
Matched Description: … In a comparison study of post menopausal women with osteoporosis and a past fracture, romosozumab for ... Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal ... Romosozumab also demonstrates a faster and larger increase in bone density than teriparatide[A177050] …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML ... EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17ML ... EVENİTY 105 MG/1,17 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADET …
Approved
Nutraceutical
Matched Synonyms: … L-ascorbic acid, calcium salt (2:1) …
Matched Iupac: … calcium bis((2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate) …
Matched Salts cas: … 5743-28-2
Matched Mixtures name: … For-2 ... Adrien Gagnon Formule A-C-E + Selenium ... Vitamin A C E W.niacinam.beta Car.and Min. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Vitamin C and analogues …
Matched Products: … CNI Well 3 Ester-C Tablet ... Vitamin C 1000mg From Ester-C Brand Ca Asc. ... Ester C
A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Approved
Experimental
Investigational
Matched Synonyms: … 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy ... 3-Rutinosyl quercetin ... Quercetin 3-rutinoside …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 ... -trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one …
Matched Description: … A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, …
Matched Salts cas: … 250249-75-3
Matched Mixtures name: … KORDEL`S C TIME ACID FREE C 1000MG TABLET ... NAT-C ... NAT-C 1000 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Pyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers. In the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat...
Approved
Matched Synonyms: … 2-pyridinethiol 1-oxide …
Matched Iupac: … 2-sulfanylpyridin-1-ium-1-olate …
Matched Description: … In the crystalline state, it exists as a centrosymmetric dimer. ... ligands chelated to zinc (2+) ions via oxygen and sulfur centers. ... pyrithione zinc has been reported for decades. …
Matched Salts cas: … 3811-73-2
Matched Mixtures name: … ReEn Mogangbichaek for Sensitive Scalp ... ReEn Hairloss Clinic Jahajin Shampoo for Sensitive Scalp …
Matched Products: … Head and Shoulders 3 In 1 Men ... Classic Clean 2 In 1 for Normal Hair ... Head & Shoulders Total Care All-IN-1 Men …
Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … [L7186] Dupilumab is commonly marketed as Dupixent, which is available as a formulation for subcutaneous ... [L7186,L7192,L41439] Dupilumab is currently under investigations for potential therapeutic use in diseases ... driven by allergic reactions or type 2 inflammation, such as pediatric atopic dermatitis, and chronic …
Matched Categories: … Agents for Dermatitis, Excluding Corticosteroids …
Matched Products: … DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 200 mg/1.14ml ... Dupixent 300 mg Solution for Injection in Pre-filled Syringe …
Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Description: … 41% for genotype 1 and 75% for genotypes 2-6 after 48 weeks of treatment. ... In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases ... being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. …
Matched Categories: … Treatments for Hepatitis C ... Compounds used in a research, industrial, or household setting ... Hepatitis C
Matched Products: … PEG-INTRON CLEARCLICK FOR INJECTION 80 mcg/0.5 ml ... PEG-INTRON CLEARCLICK FOR INJECTION 100 mcg/0.5 ml ... PEG-INTRON CLEARCLICK for Injection 50 mcg/0.5 ml …
Urofollitropin is a urinary-derived follicle-stimulating hormone (FSH) that is extracted and purified from human urine samples. It consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51...
Approved
Vet approved
Matched Description: … Urofollitropin is a urinary-derived follicle-stimulating hormone (FSH) that is extracted and purified ... use in gamete intrafallopian transfer (GIFT) or in vitro fertilization (IVF). ... Urofollitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for
Matched Products: … . - Pulver und Lösungsmittel zur Herstellung einer Injektionslösung in einer Fertigspritze ... . - Pulver und Lösungsmittel zur Herstellung einer Injektionslösung in einer Fertigspritze ... BRAVELLE POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 75 IU …
Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin...
Approved
Matched Iupac: … 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-4H,6H,7H,8H,9H-pyrido[ ... 1,2-a]pyrimidin-4-one …
Matched Description: … It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination ... Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006. ... of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism. …
Matched Products: … INVEGA 3 MG RETARDTABLETTE ... INVEGA 3 MG EXTENDED RELEASE TABLETS ... Paliperidon ratiopharm 3 mg Retardtabletten …
Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for the prevention of migraine headaches. It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. Along with other recently approved anti-CGRP therapies such as galcanezumab, erenumab, and the oral CGRP antagonist...
Approved
Investigational
Matched Description: … (CGRP) for the prevention of migraine headaches. ... Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide ... [L11749] It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. …
Matched Products: … AJOVY SOLUTION FOR INJECTION IN PRE-FILLED PEN 225 MG/1.5ML ... AJOVY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 225 MG/1.5ML ... AJOVY 225 MG/1,5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 3 ADET …
Displaying drugs 301 - 325 of 15294 in total