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Displaying drugs 76 - 100 of 714 in total
Medrysone
Medrysone is a corticosteroid used in ophthalmology.
Approved
Matched Iupac: … (1S,3aS,3bS,5S,9aR,9bS,10S,11aS)-1-acetyl-10-hydroxy-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H, …
Repotrectinib
Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for...
Approved
Investigational
Matched Synonyms: … 1,15-ETHENO-1H-PYRAZOLO(4,3-F)(1,4,8,10)BENZOXATRIAZACYCLOTRIDECIN-4(5H)-ONE, 11-FLUORO-6,7,13,14-TETRAHYDRO ... (7S,13R)-11-Fluoro-7,13-Dimethyl-6,7,13,14-Tetrahydro-1,15-Ethenopyrazolo[4,3-F][1,4,8,10]Benzoxatriazacyclotridecin …
Matched Iupac: … (3R,11S)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-pentaazatetracyclo[13.5.2.0^{4,9}.0^{18,22}]docosa …
Matched Iupac: … (3R,11S)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-pentaazatetracyclo[13.5.2.0^{4,9}.0^{18,22}]docosa …
Streptococcus pneumoniae type 11a capsular polysaccharide antigen
Streptococcus pneumoniae type 11a capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 11a of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Icosapent
Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Approved
Nutraceutical
Dihydroergocristine
Dihydroergocristine is part of the ergoloid mixture products. It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed by an alkaloid ergoline. To know more about ergoloid mixtures, please visit DB01049.
Approved
Experimental
Matched Salts cas: … 24730-10-7 …
Flumethasone
Flumethasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.
Approved
Vet approved
Ubidecarenone
Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is...
Approved
Investigational
Nutraceutical
Matched Synonyms: … Coenzyme Q-10 …
Matched Description: … From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number …
Matched Mixtures name: … Extra 11 ... Extra 11 ... Medi-10 …
Matched Products: … Coq-10 ... Co Q-10 30 mg ... Co Q-10 120mg …
Matched Description: … From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number …
Matched Mixtures name: … Extra 11 ... Extra 11 ... Medi-10 …
Matched Products: … Coq-10 ... Co Q-10 30 mg ... Co Q-10 120mg …
Minocycline
Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Quinagolide
Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated levels of prolactin or hyperprolactinaemia. Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido, as well as long-term complications such as osteoporosis . Newer dopamine receptor agonists such as quinagolide and DB00248 are...
Approved
Investigational
Capromab pendetide
Capromab is a Murine IgG1 monoclonal 7E11-C5.3 antibody that recognizes prostate specific membrane antigen (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and normal prostate tissue. When linked to pendetide, capromab is used as a chelating agent for the radionuclide Indium In-111 during imaging to evaluate...
Approved
Prednisolone
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Mixtures name: … OTIMISIN DAMLA, 10 ML …
Matched Products: … SP-CORTIL 10 SYRUP ... PREDNI H INJEKT 10 ... SOLU DECORTIN H 10 …
Matched Products: … SP-CORTIL 10 SYRUP ... PREDNI H INJEKT 10 ... SOLU DECORTIN H 10 …
Daunorubicin
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Approved
Matched Synonyms: … (8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11 …
Matched Iupac: … (8S,10S)-8-acetyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-1-methoxy …
Matched Iupac: … (8S,10S)-8-acetyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-1-methoxy …
Ketotifen
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Dihydrocodeine
Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough.
It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of...
Approved
Illicit
Matched Iupac: … (1S,5R,13R,14S,17R)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Promethazine
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171]
Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Synonyms: … 10-(2-Dimethylaminopropyl)phenothiazine ... 10-[2-(dimethylamino)propyl]phenothiazine ... N,N,α-trimethyl-10H-phenothiazine-10-ethanamine …
Matched Iupac: … dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine …
Matched Products: … PROZINE-10 SYRUP 10 mg/5 ml ... PROMAGEN 10 ORAL MIXTURE 10 mg/5 ml ... PROMETHAZIN-NEURAX 10 MG …
Matched Iupac: … dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine …
Matched Products: … PROZINE-10 SYRUP 10 mg/5 ml ... PROMAGEN 10 ORAL MIXTURE 10 mg/5 ml ... PROMETHAZIN-NEURAX 10 MG …
Cabazitaxel
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Synonyms: … .,10.BETA.-DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA. …
Matched Iupac: … tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11 …
Matched Description: … Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree …
Matched Products: … Cabazitaxel EVER Pharma 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung ... Cabazitaxel ratiopharm 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Matched Iupac: … tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11 …
Matched Description: … Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree …
Matched Products: … Cabazitaxel EVER Pharma 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung ... Cabazitaxel ratiopharm 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Methylprednisolone
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814]
Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Products: … PREDNOL 4 MG TABLET, 10 ADET …
Desloratadine
Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Approved
Investigational
Matched Synonyms: … 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine …
Matched Iupac: … 13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene …
Matched Mixtures name: … DESMONT 5/10 MG 90 FILM KAPLI TABLET ... DELOFED MR 2.5/120 MG KAPSUL, 10 ADET ... AIRCOMB 5/10 MG FILM KAPLI TABLET, 30 ADET …
Matched Products: … AXIVOL 5 MG FILM TABLET, 10 ADET ... ESLOTIN 5 MG FILM TABLET ,10 TABLET …
Matched Iupac: … 13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene …
Matched Mixtures name: … DESMONT 5/10 MG 90 FILM KAPLI TABLET ... DELOFED MR 2.5/120 MG KAPSUL, 10 ADET ... AIRCOMB 5/10 MG FILM KAPLI TABLET, 30 ADET …
Matched Products: … AXIVOL 5 MG FILM TABLET, 10 ADET ... ESLOTIN 5 MG FILM TABLET ,10 TABLET …
Iophendylate
Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). Iophendylate, which was never shown to be safe, was initially introduced for use in small amounts (1-2cc) for locating spinal tumors. It next appeared on...
Approved
Matched Synonyms: … Ethyl 10-(p-iodophenyl)-undecanoate ... Ethyl 10-(p-iodophenyl)undecylate ... Ethyl 10-(p-iodophenyl)hendecanoate …
Matched Iupac: … ethyl 10-(2-iodophenyl)undecanoate …
Matched Iupac: … ethyl 10-(2-iodophenyl)undecanoate …
Calcifediol
The major circulating metabolite of vitamin D3 (cholecalciferol). It is produced in the liver and is the best indicator of the body's vitamin D stores. It is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties.
Approved
Nutraceutical
C11-12 isoparaffin
C11-12 isoparaffin is a mixture of branched chain hydrocarbons with 11C or 12C's in the alkyl chain. It is found in cosmetic and personal care products as solvents or skin conditioning agent.
Approved
Chlorpromazine
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine ... 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine …
Matched Iupac: … [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine …
Matched Products: … ไบร์-คลอโปร 10 ... LARGACTİL 25MG ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ İÇEREN AMPUL, 10 ADET …
Matched Iupac: … [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine …
Matched Products: … ไบร์-คลอโปร 10 ... LARGACTİL 25MG ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ İÇEREN AMPUL, 10 ADET …
Gadoteric acid
Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Iupac: … gadolinium(3+) ion 2-[4,7-bis(carboxylatomethyl)-10-(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl …
Matched Products: … CLARİSCAN 0.5 MMOL/ML ENJEKSİYONLUK ÇÖZELTİ, 10 ML ... DOTAREM 0,5 MMOL/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 10 ML ... DOTAGRAF 0.5 MMOL/ML ENJEKSIYON IÇIN COZELTI ICEREN FLAKON , 10 ML …
Matched Products: … CLARİSCAN 0.5 MMOL/ML ENJEKSİYONLUK ÇÖZELTİ, 10 ML ... DOTAREM 0,5 MMOL/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 10 ML ... DOTAGRAF 0.5 MMOL/ML ENJEKSIYON IÇIN COZELTI ICEREN FLAKON , 10 ML …
Dydrogesterone
A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Approved
Investigational
Withdrawn
Matched Mixtures name: … FEMOSTON 1/10 ... FEMOSTON 1/10 ... Femoston 2/10 Tablet …
Matched Products: … Duphaston 10 mg - Filmtabletten ... DUPHASTON TABLET 10 mg (Film-coated) ... DUPHASTON 10 MG FİLM KAPLI TABLET, 20 ADET …
Matched Products: … Duphaston 10 mg - Filmtabletten ... DUPHASTON TABLET 10 mg (Film-coated) ... DUPHASTON 10 MG FİLM KAPLI TABLET, 20 ADET …
Undecylenic acid
Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat. It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones . Undecylenic acid was...
Approved
Investigational
Matched Synonyms: … 10-undecenoic acid ... ácido 10-undecenoico …
Matched Iupac: … undec-10-enoic acid …
Matched Products: … Fungi-rid - Liq 10% …
Matched Iupac: … undec-10-enoic acid …
Matched Products: … Fungi-rid - Liq 10% …
Displaying drugs 76 - 100 of 714 in total