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Displaying drugs 226 - 250 of 332 in total
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Synonyms: … 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide …
Matched Iupac: … 7-chloro-3-methyl-4H-1lambda6,2,4-benzothiadiazine-1,1-dione …
Matched Description: … Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels …
Matched Categories: … Potassium Channel Opener ... Heterocyclic Compounds, 2-Ring …
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Synonyms: … 3,3',5,5'-Tetraiodo-L-thyronine ... 3,5,3',5'-Tetraiodo-L-thyronine ... 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine …
Matched Iupac: … (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
Matched Description: … potency of ~1:4 (T4:T3). ... [F4633] T4 and T3 act on nearly every cell of the body, but have a particularly ... of the physiological effects of the thyroid hormones; T4 and T3 have a relative …
Matched Salts cas: … 6106-07-6
Matched Categories: … Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... P-glycoprotein inducers ... Cytochrome P-450 CYP2C8 Inhibitors …
Matched Products: … Levohelm 25 Mikrogramm/5 ml Lösung zum Einnehmen ... Levohelm 50 Mikrogramm/5 ml Lösung zum Einnehmen ... Levohelm 100 Mikrogramm/5 ml Lösung zum Einnehmen …
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Synonyms: … (6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione ... 1-dehydro-6α-methylhydrocortisone ... delta(1)-6alpha-Methylhydrocortisone …
Matched Iupac: … (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH ... ,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one …
Matched Salts cas: … 53-36-1
Matched Mixtures name: … Point Of Care LM DEP 2 ... P-Care D80 ... P-Care D40 …
Matched Categories: … P-glycoprotein inducers ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2A6 Inducers ... Cytochrome P-450 CYP2B6 Inducers …
Matched Products: … DEPO-MEDROL 40 MG / MLSUSPENSIONINYECTABLEX 5 ML ... PREDNOL-L 40 MG LİYOFİLİZE ENJEKTABL AMPUL, 3 ADET ... DEPO METIKORT ENJEKTABL FLAKON AMPUL, 1 ADET …
Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched International brands: … Betalin S
Matched Synonyms: … thiamine(1+) ... thiamine(1+) ion …
Matched Iupac: … 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium …
Matched Salts cas: … 532-43-4
Matched Mixtures name: … RUBIRON+6 AMPUL, 5 ADET ... P-NATAL® ... Chela Potassium Plus …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … VI-PLEX B1 250 MG/2 ML AMPUL, 5 ADET ... BEVIGEN 2 ML AMPUL, 3 ADET ... VI-PLEX B1 200 MG/2 ML AMPUL, 3 ADET …
Oxcarbazepine is an anti-epileptic medication used in the treatment of partial onset seizures that was first approved for use in the United States in 2000.[L8627,L8630,L8633] It is a structural derivative of carbamazepine and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate...
Approved
Matched Synonyms: … 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide …
Matched Iupac: … 9-oxo-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaene-2-carboxamide …
Matched Description: … pharmacologically active metabolite, MHD, which exists as a racemate in the blood - a pro-drug of the more active (S) …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... P-glycoprotein inducers ... P-glycoprotein substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers …
Matched Products: … DEPRECTAL-S ... TRILEPTAL® 6 % SUSPENSION …
Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. Levacetylmethadol was withdrawn from use in the European Union due to its high risk of QT interval prolongation. The production of levacetylmethadol in the US has ceased...
Approved
Investigational
Withdrawn
Matched Synonyms: … (1S,4S)-4-(dimethylamino)-1-ethyl-2,2-diphenylpentyl acetate ... 1-alpha-Acetylmethadol …
Matched Iupac: … (3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate …
Matched Salts cas: … 43033-72-3
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Cytochrome P-450 CYP3A7 Substrates ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Synonyms: … delta(1)-Hydrocortisone ... delta(1)-Dehydrocortisol ... delta(1)-Dehydrohydrocortisone …
Matched Iupac: … (1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H, ... 5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one …
Matched Categories: … P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 Enzyme Inducers …
Matched Products: … PRELONE SYRUP 3 mg/5 ml ... P-PRED ... อาร์พี-โซโลน 2
Approved
Nutraceutical
Matched Synonyms: … Ascorbic acid sodium salt ... L-Ascorbic acid sodium salt ... L-Ascorbic acid, monosodium salt …
Matched Iupac: … sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... P-NATAL® ... Irospan 24/6
Matched Categories: … Carboxylic Acids …
Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions. Sodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances. Sodium sulfate...
Approved
Vet approved
Matched Synonyms: … Sulfuric acid disodium salt, anhydrous …
Matched Description: … Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. …
Matched Salts cas: … 7727-73-3
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... Sodium Polysulthionate, 5-mthf ... Sodium polysulthionate and folic acid
Hydrocodone is a synthetic opioid derivative of codeine. It is commonly used in combination with acetaminophen to control moderate to severe pain. Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by dextromethorphan in current cough and cold formulations. Hydrocodone's more potent metabolite, hydromorphone...
Approved
Illicit
Investigational
Matched Synonyms: … 4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-6-one …
Matched Iupac: … (1S,5R,13R,17R)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca- ... 7(18),8,10-trien-14-one …
Matched Salts cas: … 34195-34-1 ... 25968-91-6
Matched Mixtures name: … P-Tuss ... Hycomine-S ... Xodol 5/300 …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2D6 Substrates …
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Synonyms: … 3-pyridinecarboxamide ... Nicotinic acid amide …
Matched Iupac: … pyridine-3-carboxamide …
Matched Salts cas: … 25334-23-0
Matched Mixtures name: … MINOXIDIL 7% / NIACINAMIDE 4% s ... Dapsone 6% / Niacinamide 2% / Spironolactone 5% ... 011503 Dapsone 6% / Niacinamide 2% / Spironolactone 5% …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2D6 Inhibitors ... Cytochrome P-450 CYP2E1 Inhibitors ... Cytochrome P-450 CYP3A Inhibitors …
Matched Products: … Costem cell 5 N ... Brextem S ... วิตามิน บี 3 (ไนอาซินาไมด์-250) …
Approved
Investigational
Matched Synonyms: … Acetic acid, zinc salt …
Matched Iupac: … zinc(2+) diacetate …
Matched Salts cas: … 5970-45-6
Matched Categories: … Carboxylic Acids …
Azilsartan medoxomil is a prodrug that is broken down to azilsartan, which belongs in the angiotensin-receptor blocking (ARB) drug class. It is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan medoxomil is a relatively recently-developed antihypertensive drug that was first approved by the FDA in February 2011. Many guidelines...
Approved
Investigational
Matched Iupac: … (5-methyl-2-oxo-2H-1,3-dioxol-4-yl)methyl 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-[1,1 ... '-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylate …
Matched Salts cas: … 863031-24-7
Matched Salts name: … Azilsartan medoxomil potassium
Matched Categories: … Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Angiotensin II Type 1 Receptor Blockers ... P-glycoprotein inhibitors …
Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class . These heparins have lower...
Approved
Investigational
Matched Products: … HIBOR 2500 IU/0,2 ML KULLANIMA HAZIR 2 ENJEKTOR ... HIBOR 5000 IU/0,2 ML SC KULLANIMA HAZIR ENJEKTÖR, 2 ADET ... HIBOR 10000 IU/0,4 ML SC KULLANIMA HAZIR ENJEKTÖR, 2 ADET …
Thallous chloride (also known as Thallium(I) chloride) is a colourless solid intermediate in the isolation of thallium from its ores. It is created from the treatment of thallium(I) sulfate with hydrochloric acid. This solid crystallizes in the caesium chloride motif. It is used as a diagnostic radiopharmaceutical. It is used...
Approved
Matched Description: … It is created from the treatment of thallium(I) sulfate with hydrochloric acid. …
Matched Products: … Thalliumchlorid (201TI) CIS bio international Injektionslösung TL-201-S-1 ... TAEK-PHT 201-TlCl (TALYUM KLORÜR) 37 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... MON.TALYUM-201 IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 2 MCİ (ÇARŞAMBA KAL. PTSİ.TES) …
Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed...
Approved
Vet approved
Matched Description: … 1 ratio of sodium and chloride ions. ... common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1: …
Matched Mixtures name: … D-5-1/2S ... D-5-1/3 S ... Lactate 1-2-3 Injection …
Matched Products: … Sterile Hypertonic Saline Solution 7 Sodium Chloride ... Muro 128 Oph Soln 2% ... Saline Nasal 1 fl oz …
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone...
Approved
Matched Iupac: … 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl ... ]methyl}-1H-1,3-benzodiazole-7-carboxylate …
Matched Description: … renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1
Matched Mixtures name: … CANDESAR HEN P HCT 8/12.5 ... CANDESAR HEN P HCT 8/12.5 ... CANDESAR HEN P HCT 8/12.5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 2-Ring ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates …
Matched Products: … Candeblo 2 mg - Tabletten ... Candesartan G.L. 2 mg - Tabletten ... Atacand 4 mg - Tabletten …
Nateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release. Nateglinide is an amino acid derivative that induces an early insulin...
Approved
Investigational
Matched Iupac: … (2R)-3-phenyl-2-{[(1r,4r)-4-(propan-2-yl)cyclohexyl]formamido}propanoic acid
Matched Description: … Nateglinide is an amino acid derivative that induces an early insulin response to meals decreasing postprandial …
Matched Categories: … Potassium Channel Blockers ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Amino Acids, Peptides, and Proteins …
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822)
Approved
Investigational
Withdrawn
Matched Iupac: … 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... hydroflumethiazide and potassium
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Iupac: … 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related ... disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid
Matched Salts cas: … 95382-33-5 ... 95510-70-6
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Acid Reducers ... 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring ... Gastric Acid Lowering Agents …
Matched Products: … OMEPRAZOLO P-CARE ... OMEPRAZOLO HEXAL A/S ... Acid Reducer …
Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. It also relaxes vascular smooth muscle by opening adenosine triphosphate sensitive potassium channels. Levosimendan is used to manage acutely decompensated congestive heart failure.
Approved
Investigational
Matched Iupac: … 1-cyano-N-{4-[(4R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl]phenyl}methanecarbohydrazonoyl cyanide …
Matched Description: … It also relaxes vascular smooth muscle by opening adenosine triphosphate sensitive potassium channels …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Phosphodiesterase 3 Inhibitors …
Matched Products: … SIMDAX 2.5 MG/ML KONSANTRE INF.COZ.5 ML X FLAKON, 1 ADET ... SİMELEV 12,5 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET ... SİMENDAN 12.5 MG/5 ML I.V. İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.
Approved
Matched Iupac: … 4-phenoxy-3-(pyrrolidin-1-yl)-5-sulfamoylbenzoic acid
Matched Mixtures name: … RAMIPRIL PIRETA 1A PHA 5/6 ... RAMIPRIL PIRETA 1A PHA 5/6 ... RAMIPRIL PIRETA 1A PHA 5/6
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors …
Matched Products: … ARELIX MITE 3 ... PIRETANID 3 1A PHARMA ... ARELIX 6
Oxaprozin is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID), used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis.
Approved
Matched Iupac: … 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid
Matched Salts cas: … 174064-08-5
Matched Salts name: … Oxaprozin potassium
Matched Categories: … Carboxylic Acids ... Arylpropionic acid NSAIDS ... Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 1-Ring …
Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Approved
Matched Iupac: … magnesium(2+) dichloride …
Matched Salts cas: … 7791-18-6 ... 22756-14-5
Matched Mixtures name: … Isolyte R In 5% Dextrose ... Normosol-R & 5% Dextrose ... 4.25%travasol Amino Acid InJ.W.elecw.5%dex. …
Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Matched Iupac: … )-5-[(diaminomethylidene)amino]pentanamide; 6-amino-2-({1-[19-amino-13-benzyl-10-(2-carbamoylethyl)-7 ... 2-({1-[19-amino-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18 ... -(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane ... -4-carbonyl]pyrrolidin-2-yl}formamido)-N-(carbamoylmethyl)hexanamide ... -pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl]pyrrolidin-2-yl}formamido)-N-(carbamoylmethyl …
Matched Description: … /sub> and V2 cellular receptors. ... during systemic shock by increasing vasoconstriction and renal fluid reuptake by acting through V1< ... A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino
Matched Salts cas: … 113-79-1
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ./2 ml Konzentrat zur Herstellung einer Infusionslösung …
Displaying drugs 226 - 250 of 332 in total