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Displaying drugs 26 - 50 of 5687 in total
Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective...
Approved
Matched Description: … It manages and prevents dental caries and gingivitis by promoting enamel mineralization [A19580], reducing ... compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and ... Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Crest 3D White Brilliance Daily Cleansing and Whitening System ... SENSODYNE Repair and Protect ... Equate Repair and Protect
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins
Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Matched Iupac: … zirconium(4+) aluminium(3+) 2-aminoacetate dihydrate chloride …
Matched Description: … It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. ... Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and
Matched Mixtures name: … Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN …
Matched Products: … Bath and Body Works Graphite ... Secret American Chic Invisible ... Secret American Bloom Invisible …
Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …
Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … enhanced secretion of bile acids and lipids in the feces, patients who take complicated medication regimens ... [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia …
Matched Salts cas: … 37296-80-3
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity …
Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … receptor and a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein ... Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 …
Matched Description: … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of ... a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe …
A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Description: … It is used as an ointment base, topical protectant, and lubricant. …
Matched Mixtures name: … Aquaphor Lip Repair and Protect ... Soothe and Cool Protect ... Shield and Protect Barrier Cream …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … L-Topical WHITE PETROLATUM 30% ... Repair and Protect ... Soothe and Cool Protect
Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Investigational
Matched Synonyms: … Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13) …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in …
Nutraceutical
Matched Mixtures name: … frida mom Labor and Delivery Plus Postpartum Recovery ... frida mom Labor and Delivery Plus Postpartum Recovery ... Tucks Multi-Care Relief Kit (Tucks Hemorrhoidal and Tucks Medicated Cooling 40 Count) …
Matched Categories: … Astringents and Deodorants ... Herbs and Natural Products ... Skin and Mucous Membrane Agents …
Matched Products: … W Lab EGG PORE MASK ... Up and Up Medicated Hemorrhoidal Pads ... Tone and Line Change Pack …
Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Gp96-igg1-fc fusion protein and hla-a1 expressing, irradiated ad-100 whole cell vaccine ... Viagenpumatucel l ... Viagenpumatucel-L
Matched Name: … Viagenpumatucel-L
Matched Description: … Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Synonyms: … L(−)-nicotine ... 3-(N-methylpyrollidino)pyridine ... (S)-3-(1-methylpyrrolidin-2-yl)pyridine …
Matched Iupac: … 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine …
Matched Description: … the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and
Matched Salts cas: … 65-31-6 ... 6019-06-3
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening …
Matched Products: … NIQUITINPARCHE TRANSDERMICO POR 21 MG ETAPA 1 ... NIQUITIN®PARCHE TRANSDERMICO POR 14 MG ETAPA 2 ... American Fare Nicotine Transdermal System …
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Description: … In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. ... Allantoin is a substance that is endogenous to the human body and also found as a normal component of ... During exercise, the plasma allantoin concentration rapidly increases about two fold and remains elevated …
Matched Mixtures name: … Triderma Protect and Heal Non- Greasy Barrier ... Dual Treatment - Cold Sore Therapy and Daily Lip Maintenance ... bdr Re-lax 3 multiple level serum highly-potential youth …
Matched Categories: … Basic Ointments and Protectants ... Herbs and Natural Products …
Matched Products: … Cetaphil Baby Soothe and Protect Cream ... 3ce Fixer and Mascara Black ... 3ce Fixer and Mascara Brown …
DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and
CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Phosphatidic Acids ... Proteins ... Membrane Proteins ... Pulmonary Surfactant-Associated Proteins
Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration ... with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and ... As a result of these concerns, hydroquinone has been banned in the EU and UK. …
Matched Mixtures name: … CREMA CON ACIDO GLICOLICO AL 8% ... Condition and Enhance System Travel-size Non-surgical ... Condition and Enhance System Travel-size Non-surgical …
Matched Products: … AMERICA ... I-max Lightening L ... Celazome Fade Shades Lightening Cream w/ Glycolic Acid
Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched International brands: … Signifor LAR
Matched Synonyms: … cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L
Matched Iupac: … 3-yl)methyl]-1,4,7,10,13,16-hexaoxo-3-phenyl-icosahydropyrrolo[1,2-a]1,4,7,10,13,16-hexaazacyclooctadecan ... (3S,6R,9S,12S,15S,19R,20aS)-9-(4-aminobutyl)-15-benzyl-12-{[4-(benzyloxy)phenyl]methyl}-6-[(1H-indol- …
Matched Salts cas: … 396091-76-2 ... 396091-79-5 …
Matched Salts name: … Pasireotide acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Pituitary and Hypothalamic Hormones and Analogues ... Hypothalamic Hormones ... Proteins
Matched Products: … SIGNIFOR LAR (30 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …
Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … amino acid, 170 kDa protein [FDA Label]. ... factor VIII due to conjugation to the dimeric Fc domain of human immunoglobulin G1, a long-lived plasma ... purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Protein Precursors ... Recombinant Proteins
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …
VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking ... the CD33 protein
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy ... product lacking the CD33 protein. …
Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli. People take sulfur...
Approved
Matched Description: … Sulfur is also found in garlic, onions and broccoli. ... After calcium and phosphorus, it is the third most abundant mineral in the human body. ... allergies, swelling in the back of the throat (pharyngitis), high cholesterol, clogged arteries, menopause, and
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid ... Dermaharmony Sulfur and Salicylic Acid
Matched Products: … Acne All-Star 3-in-1 Acne Cleanser, Mask and Spot Treatment ... Spai-sons Acid Anti-dandruff ... Rodan and Fields Unblemish 1 Wash Acne Medicated Cleanser …
Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … [A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover ... administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins
Matched Mixtures name: … Target Up and Up 3 Step Acne System ... Target Up and Up 3 Step Acne System ... BenzoDox 30 Kit …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … Clean and Clear Advantage 3 in 1 Exfoliating ... Clean and Clear Advantage 3-in-1 Exfoliating Cleanser ... Clinac Bpo 7
Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Approved
Matched Synonyms: … Phosphorofluoridic acid, disodium salt ... Disodium phosphorofluoridate …
Matched Iupac: … disodium phosphorofluoridate …
Matched Description: … Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities. …
Matched Mixtures name: … Mentadent Specialty Whitening Toothpaste and Polishing ... Hawaiian Airline EC with Colgate Toothbrush and Sun ... Chunzam Silk Amino Acid Tooth …
Matched Categories: … Alimentary Tract and Metabolism ... Acids ... Acids, Noncarboxylic ... Phosphoric Acids ... Phosphorus Acids
Matched Products: … BlanX White Shock White and Protect ... vVARDIS Switzerland Edelweiss White and Protect Fluoride Tooth Strong Mint ... 365 Everyday Value Cavity Fighting and Whitening …
ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Investigational
Matched Synonyms: … humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and
Matched Description: … ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK). …
Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... PEGylation is the covalent attachment of a polyethylene glycol polymer, called PEG, to a drug or protein
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Protein Precursors ... Recombinant Proteins
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Iupac: … -3-(naphthalen-2-yl)propanamido]propanamido]-3-(pyridin-3-yl)propanamido]-3-hydroxypropanamido]ethyl] ... [(1R)-1-carbamoylethyl]carbamoyl}pyrrolidin-1-yl]-1-oxo-6-[(propan-2-yl)amino]hexan-2-yl]carbamoyl}-3- ... methylbutyl]carbamoyl}ethyl]carbamoyl}-2-[(2S)-2-[(2R)-2-[(2R)-3-(4-chlorophenyl)-2-[(2R)-2-acetamido …
Matched Description: … This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately ... derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and ... are D-amino acids. …
Matched Salts cas: … 934246-14-7
Matched Salts name: … Degarelix acetate hydrate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …
Displaying drugs 26 - 50 of 5687 in total