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Displaying drugs 576 - 600 of 601 in total

Doxycycline

Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Matched Description: … It is also used to treat acne and malaria.[A251730] ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections …
Matched Salts name: … Doxycycline calcium …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Vibramycin Calcium …

Idursulfase beta

Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Investigational
Matched Synonyms: … Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform …
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Amaranthus retroflexus whole

Amaranthus retroflexus whole allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Red-root amaranth whole …

Bromhexine

Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Description: … and reducing cough. ... It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing ... prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs. …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … BISOLVON® TABLETAS SOLUBLES …

Exisulind

Investigational
Matched Synonyms: … Sulindac sulfone …

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Synonyms: … Calciol …
Matched Description: … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus ... C23 and has an additional methyl group at C24 [L5689]. ... of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and …
Matched Mixtures name: … Calcium and Magnesium With Vitamin D ... Calcium and Magnesium With Vitamin D ... Calcium With Magnesium and Vitamin D …
Matched Categories: … Calcium-Regulating Hormones and Agents ... zoledronic acid, calcium and colecalciferol, sequential ... alendronic acid, calcium and colecalciferol, sequential ... risedronic acid, calcium and colecalciferol, sequential ... Alimentary Tract and Metabolism …

Oxfendazole

Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.
Investigational
Vet approved
Matched Synonyms: … Fenbendazole sulfoxide …
Matched Description: … This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. ... Oxfendazole is a sulfoxide metabolite of fenbendazole. …

St. John's Wort

Approved
Investigational
Nutraceutical
Matched Synonyms: … Hypoxis hemerocallidea root extract …
Matched Categories: … Herbs and Natural Products …

3,6-Anhydro-2-(hydrogen sulfate)-alpha-D-galactopyranose

Experimental
Matched Name: … 3,6-Anhydro-2-(hydrogen sulfate)-alpha-D-galactopyranose …

Durlobactam

Durlobactam is a diazabicyclooctane non-beta-lactam, beta-lactamase inhibitor. It is typically given in combination with sulbactam to protect it from degradation by certain serine-beta-lactamases. The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023. It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial...
Approved
Investigational
Matched Synonyms: … (2S,5R)-2-CARBAMOYL-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL SULFATE …
Matched Description: … [L47336] The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023 ... [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial …

Viper antivenom

Viper antivenom consists of antibodies derived from horses immunized and subsequently developed antibodies against snake venoms. ANAVIP, an equine-derived antivenom made with venom from Bothrops asper and Crotalus durissus, was first approved by the FDA on October 1, 2015, for the management of North American rattlesnake envenomation.
Approved
Matched Synonyms: … Antivenin (bothrops atrox/crotalus adamanteus/crotalus atrox/crotalus durissus terrificus) (equine) …
Matched Description: … Viper antivenom consists of antibodies derived from horses immunized and subsequently developed antibodies ... ANAVIP, an equine-derived antivenom made with venom from _Bothrops asper_ and _Crotalus durissus_, was …

2-deoxy-2-acetamido-beta-D-galactose-4-sulfate

Experimental
Matched Name: … 2-deoxy-2-acetamido-beta-D-galactose-4-sulfate …

Sulbactam

Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.
Approved
Matched Synonyms: … Penicillanic acid sulfone …
Matched Description: … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. …
Matched Mixtures name: … SULCID 2G IM/IV 1 FLAKON ... SULCID IM/IV 250 MG 1 FLAKON ... SULCID IM 1 GR FLAKON, 1 ADET …

Tobramycin

Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Description: … concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and ... [A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to ... L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and …
Matched Mixtures name: … Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone …
Matched Salts name: … Tobramycin sulfate …
Matched Products: … Tobramycin Sulfate …

Ceftriaxone

Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Products: … Ceftriaxone and Dextrose …

Bosentan

Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Description: … blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … SULMIDA® 62.5 MG TABLETAS RECUBIERTAS …

Cefuroxime

Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …

Piroxicam

A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Description: … osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. ... non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … STOPEN TABLETAS SOLUBLES …

Avutometinib

Avutometinib (RO-5126766 free base) is under investigation in clinical trial NCT03875820 (Phase I Trial of VS-6063 and RO5126766.).
Investigational
Matched Synonyms: … Sulfamide, N-(3-fluoro-4-((4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl)methyl)-2-pyridinyl …
Matched Description: … RO-5126766 free base) is under investigation in clinical trial NCT03875820 (Phase I Trial of VS-6063 and …

Cyclosporine

Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products...
Approved
Investigational
Vet approved
Matched Description: … treat various inflammatory and autoimmune conditions. ... calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and ... [A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Cyclosporine/Chondroitin Sulfate PF …

(3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine

Experimental
Matched Name: … (3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine …
Matched Iupac: … (2S,3R)-4-{[2-(3,4-dihydroxyphenyl)acetyl]oxy}-2-[(2-formylindolizin-3-yl)amino]-3-methyl-3-[(S)-sulfino …

Mesalazine

An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical...
Approved
Matched Description: … An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory ... Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine ... Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine …
Matched Products: … sfRowasa Sulfite-Free Formulation …

Meloxicam

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and...
Approved
Vet approved
Matched International brands: … Atrozan …
Matched Description: … Meloxicam is available in oral, transdermal, and intravenous formulations. ... relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and …
Matched Categories: … bupivacaine and meloxicam ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Tretinoin

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Synonyms: … ATRA …
Matched Description: … Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin ... activates nuclear receptors to regulate epithelial cell growth and differentiation. ... [A257689] Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging …
Matched Mixtures name: … Clindamycin Phosphate and Tretinion ... OLIVIA QUIDO FIRM and FADE I ... OLIVIA QUIDO FIRM and FADE II …
Matched Categories: … Cell Stimulants and Proliferants ... Antineoplastic and Immunomodulating Agents …

Diclofenac

Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Description: … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... PGs contribute to inflammation and pain signalling. ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Arthritis Pain Reliever …
Displaying drugs 576 - 600 of 601 in total