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Displaying drugs 51 - 75 of 891 in total
Testolactone
An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
Approved
Investigational
Matched Synonyms: … 1-dehydrotestololactone ... delta(1)-testololactone …
Matched Description: … An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer …
Matched Description: … An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer …
Fluconazole
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Iupac: … 2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol …
Matched Description: … superficial fungal infections in a variety of tissues. ... This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. ... Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and …
Matched Mixtures name: … Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% ... Canesoral Combi 1 Day ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Categories: … Imidazole and Triazole Derivatives ... Triazole and tetrazole derivatives ... azithromycin, fluconazole and secnidazole ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … FLUCAN 150 MG KAPSUL, 12 ADET ... FLUZAMED 150 MG KAPSÜL ,12 KAPSÜL ... FLUCONAZOL 50 1A PHARMA …
Matched Description: … superficial fungal infections in a variety of tissues. ... This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. ... Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and …
Matched Mixtures name: … Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% ... Canesoral Combi 1 Day ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Categories: … Imidazole and Triazole Derivatives ... Triazole and tetrazole derivatives ... azithromycin, fluconazole and secnidazole ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … FLUCAN 150 MG KAPSUL, 12 ADET ... FLUZAMED 150 MG KAPSÜL ,12 KAPSÜL ... FLUCONAZOL 50 1A PHARMA …
Xenon Xe-127
Approved
Olopatadine
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Iupac: … 2-[(2Z)-2-[3-(dimethylamino)propylidene]-9-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen …
Matched Description: … Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating ... It is a structural analog of [doxepin], which has a minimal anti-allergic activity. ... seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. …
Matched Mixtures name: … OFNOL FRESH % 0.1 + %0.15 STERİL OFTALMİK ÇÖZELTİ, 1 ADET …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … OLO-A-DAY ... Pataday Twice A Day Relief ... Eye Allergy Itch and Redness Relief …
Matched Description: … Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating ... It is a structural analog of [doxepin], which has a minimal anti-allergic activity. ... seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. …
Matched Mixtures name: … OFNOL FRESH % 0.1 + %0.15 STERİL OFTALMİK ÇÖZELTİ, 1 ADET …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … OLO-A-DAY ... Pataday Twice A Day Relief ... Eye Allergy Itch and Redness Relief …
Alprazolam
Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms. Alprazolam's adverse...
Approved
Illicit
Investigational
Matched Synonyms: … 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Iupac: … 12-chloro-3-methyl-9-phenyl-2,4,5,8-tetraazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13-hexaene …
Matched Description: … Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. ... ketoconazole and itraconazole. ... of the drug which may lead to coma and death. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … ALPRAZOLAM 1A PHARMA 1MG ... ALPRAZOLAM 1A PHARMA 0.5MG ... ATARAX 1 …
Matched Iupac: … 12-chloro-3-methyl-9-phenyl-2,4,5,8-tetraazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13-hexaene …
Matched Description: … Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. ... ketoconazole and itraconazole. ... of the drug which may lead to coma and death. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … ALPRAZOLAM 1A PHARMA 1MG ... ALPRAZOLAM 1A PHARMA 0.5MG ... ATARAX 1 …
Demeclocycline
A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Description: … A tetracycline analog having a 7-chloro and a 6-methyl. …
Alfuzosin
Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases...
Approved
Investigational
Matched Description: … Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads ... [A228483] Alfuzosin is an alpha-1 adrenergic blocker used in the symptomatic treatment of BPH that works ... by relaxing the muscles in the prostate and bladder neck. …
Matched Salts cas: … 81403-68-1 …
Matched Categories: … alfuzosin and finasteride ... Genito Urinary System and Sex Hormones ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists ... Selective Alfa-1-adrenergic Blocking Agents …
Matched Products: … ALFUZOSIN 5MG 1A PHARMA ... ALFUZOSIN 10MG 1A PHARMA …
Matched Salts cas: … 81403-68-1 …
Matched Categories: … alfuzosin and finasteride ... Genito Urinary System and Sex Hormones ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists ... Selective Alfa-1-adrenergic Blocking Agents …
Matched Products: … ALFUZOSIN 5MG 1A PHARMA ... ALFUZOSIN 10MG 1A PHARMA …
Chlorhexidine
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Iupac: … N-(4-chlorophenyl)-1-{N'-[6-(N-{[N'-(4-chlorophenyl)carbamimidamido]methanimidoyl}amino)hexyl]carbamimidamido …
Matched Description: … Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental ... [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two ... biguanide groups joined by a central hexamethylene chain. …
Matched Salts cas: … 56-95-1 …
Matched Mixtures name: … CLIORO ORAL SPREY, 1 ADET ... Hexifoam-skin Disinfectant Aer 1% ... easyangin Zitronengeschmack 5 mg/1 mg Lutschtabletten …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Biguanides and Amidines ... Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... Antiseptics and Disinfectants …
Matched Products: … Alsoft A Hand Disinfectant 0.2% w/v ... Foster and Thrive ... Hexigel 1% w/w …
Matched Description: … Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental ... [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two ... biguanide groups joined by a central hexamethylene chain. …
Matched Salts cas: … 56-95-1 …
Matched Mixtures name: … CLIORO ORAL SPREY, 1 ADET ... Hexifoam-skin Disinfectant Aer 1% ... easyangin Zitronengeschmack 5 mg/1 mg Lutschtabletten …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Biguanides and Amidines ... Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... Antiseptics and Disinfectants …
Matched Products: … Alsoft A Hand Disinfectant 0.2% w/v ... Foster and Thrive ... Hexigel 1% w/w …
Tildrakizumab
Tildrakizumab is a high-affinity, humanized, IgG1 κ antibody targeting interleukin 23 p19 that shows promise in the evolution of treatment strategy in chronic plaque psoriasis .
The Food and Drug Administration (FDA) approved ILUMYA (tildrakizumab-asmn) for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy...
Approved
Investigational
Matched Description: … Tildrakizumab is a high-affinity, humanized, IgG1 κ antibody targeting interleukin 23 p19 that shows ... 12 weeks thereafter [L1858]. ... The approved recommended dosage of ILUMYA is a subcutaneous injection of 100 mg at Weeks 0, 4, and every …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interleukin Inhibitors ... Interleukin-23 Antagonist ... Interleukin-23 Subunit p19 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interleukin Inhibitors ... Interleukin-23 Antagonist ... Interleukin-23 Subunit p19 …
Labetalol
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730]
Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Synonyms: … 5-(1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide ... 3-Carboxamido-4-hydroxy-alpha-((1-methyl-3-phenylpropylamino)methyl)benzyl alcohol …
Matched Iupac: … 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide …
Matched Description: … [L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.[L7724] ... Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up …
Matched Categories: … Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists ... Alpha and Beta Blocking Agents and Thiazides ... labetalol and thiazides ... Alpha and Beta Blocking Agents …
Matched Products: … BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) …
Matched Iupac: … 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide …
Matched Description: … [L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.[L7724] ... Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up …
Matched Categories: … Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists ... Alpha and Beta Blocking Agents and Thiazides ... labetalol and thiazides ... Alpha and Beta Blocking Agents …
Matched Products: … BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) …
Topiramate
Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Synonyms: … 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate …
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen. ... [A175249] Interestingly, topiramate was discovered by chance when attempts were made to formulate a novel …
Matched Salts cas: … 488127-51-1 …
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Matched Products: … TOPIRAMAT 1A PHARMA 25MG ... TOPIRAMAT 1A PHARMA 50MG ... TOPIRAMAT 1A PHARMA 100MG …
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen. ... [A175249] Interestingly, topiramate was discovered by chance when attempts were made to formulate a novel …
Matched Salts cas: … 488127-51-1 …
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Matched Products: … TOPIRAMAT 1A PHARMA 25MG ... TOPIRAMAT 1A PHARMA 50MG ... TOPIRAMAT 1A PHARMA 100MG …
Perindopril
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Synonyms: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic …
Matched Iupac: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor ... Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of …
Matched Mixtures name: … PERINDO IN 1A PHA4/1.25MG ... PERINDO IN 1A PHA4/1.25MG ... PERINDO IN 1A PHA2/0.625MG …
Matched Categories: … ACE Inhibitors and Diuretics ... perindopril and diuretics ... perindopril and bisoprolol ... perindopril and amlodipine ... atorvastatin and perindopril …
Matched Products: … PERINDOPRIL ERB 1A PH 4MG …
Matched Iupac: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor ... Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of …
Matched Mixtures name: … PERINDO IN 1A PHA4/1.25MG ... PERINDO IN 1A PHA4/1.25MG ... PERINDO IN 1A PHA2/0.625MG …
Matched Categories: … ACE Inhibitors and Diuretics ... perindopril and diuretics ... perindopril and bisoprolol ... perindopril and amlodipine ... atorvastatin and perindopril …
Matched Products: … PERINDOPRIL ERB 1A PH 4MG …
Motixafortide
Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation. Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - high-dose chemotherapy regimens destroy cancerous blood cells, which are then replaced via infusion of the patient's...
Approved
Investigational
Matched Description: … Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection ... previously approved [plerixafor], motixafortide is an inhibitor of C-X-C Motif Chemokine Receptor 4 (CXCR4), a …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ziprasidone
Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Iupac: … 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-2,3-dihydro-1H-indol-2-one …
Matched Description: … [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower ... abuse, and can significantly impact the quality of life of patients and caregivers. ... Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … ICIN KURU TOZ ICEREN FLAKON 20MG/ML FLAKON, 1 ADET ... ZIPRASIDON 1A PHARMA 20MG ... ZIPRASIDON 1A PHARMA 40MG …
Matched Description: … [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower ... abuse, and can significantly impact the quality of life of patients and caregivers. ... Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … ICIN KURU TOZ ICEREN FLAKON 20MG/ML FLAKON, 1 ADET ... ZIPRASIDON 1A PHARMA 20MG ... ZIPRASIDON 1A PHARMA 40MG …
Tacrolimus
Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Iupac: … (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl ... ]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo …
Matched Description: … It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein ... ) creating a new complex. ... uveitis after bone marrow transplants, and the skin condition vitiligo. …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% ... Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% …
Matched Categories: … Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Products: … TACROCIN 1- TACROLIMUS CAPSULE USP 1 MG ... TACLIM 1 MG ... ADVAGRAF(R) 1 MG …
Matched Description: … It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein ... ) creating a new complex. ... uveitis after bone marrow transplants, and the skin condition vitiligo. …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% ... Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% …
Matched Categories: … Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Products: … TACROCIN 1- TACROLIMUS CAPSULE USP 1 MG ... TACLIM 1 MG ... ADVAGRAF(R) 1 MG …
Iobenguane
Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved...
Approved
Investigational
Matched Description: … Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. ... Images are produced by a I123 MIBG scintigraphy. FDA approved on September 19, 2008. ... Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. …
Matched Salts cas: … 76924-93-1 …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Matched Salts cas: … 76924-93-1 …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Ruxolitinib
Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. It is a potent and selective inhibitor of JAK1 and JAK2, which are tyrosine kinases involved in cytokine signalling and hematopoiesis. Myeloproliferative neoplasms, such as myelofibrosis and polycythemia vera, are often characterized by...
Approved
Matched Iupac: … (3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)propanenitrile …
Matched Description: … It is a potent and selective inhibitor of JAK1 and JAK2,[A229698] which are tyrosine kinases involved ... Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor ... [A229708] Due to a large number of patients with myeloproliferative neoplasms who have JAK2 mutations …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … It is a potent and selective inhibitor of JAK1 and JAK2,[A229698] which are tyrosine kinases involved ... Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor ... [A229708] Due to a large number of patients with myeloproliferative neoplasms who have JAK2 mutations …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Febuxostat
Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Description: … a joint, leading to inflammation and further deposition of uric acid crystal deposition in bones, joints ... Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. ... , tissues, and other organs in the long term. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … FEBUXOSTAT 1A PHARMA 80MG ... FEBUXOSTAT 1A PHARMA 120MG …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … FEBUXOSTAT 1A PHARMA 80MG ... FEBUXOSTAT 1A PHARMA 120MG …
Zidovudine
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator...
Approved
Matched Iupac: … 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during ... It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves ... Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia …
Matched Mixtures name: … N/A ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... zidovudine and lamivudine ... zidovudine, lamivudine and abacavir ... zidovudine, lamivudine and nevirapine …
Matched Products: … RETROVIR IV FOR INFUSION 1% …
Matched Description: … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during ... It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves ... Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia …
Matched Mixtures name: … N/A ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... zidovudine and lamivudine ... zidovudine, lamivudine and abacavir ... zidovudine, lamivudine and nevirapine …
Matched Products: … RETROVIR IV FOR INFUSION 1% …
Amlexanox
Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of...
Approved
Investigational
Withdrawn
Matched International brands: … OraDisc A …
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid …
Matched Description: … Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. ... Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and ... aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and …
Matched Categories: … Alimentary Tract and Metabolism ... Heterocyclic Compounds, 1-Ring …
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid …
Matched Description: … Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. ... Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and ... aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and …
Matched Categories: … Alimentary Tract and Metabolism ... Heterocyclic Compounds, 1-Ring …
Omaveloxolone
Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory properties.[A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress. In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 pathway is impaired, and Nrf2 activity...
Approved
Investigational
Matched Description: … Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory ... adolescents aged 16 years and older. ... pathway is impaired, and Nrf2 activity is lower. …
Pyridoxine
Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA) [A32837]. ... As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required ... It's important to note that Vitamin B6 is the collective term for a group of three related compounds, …
Matched Mixtures name: … .-12 ... M.V.I. 12 ... AVETAL-12 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... isoniazid, sulfamethoxazole, trimethoprim and pyridoxine …
Matched Mixtures name: … .-12 ... M.V.I. 12 ... AVETAL-12 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... isoniazid, sulfamethoxazole, trimethoprim and pyridoxine …
Bimatoprost
Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. It has the ability to reduce ocular hypotension, proving effective in conditions such as...
Approved
Investigational
Matched Synonyms: … (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept …
Matched Description: … Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which ... in 2008, as eyelash growth became a desirable adverse effect for patients using this drug. ... Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. …
Matched Mixtures name: … Bimatoprost/Timolol 1A Pharma 0,3 mg/ml + 5 mg/ml - Augentropfen, Lösung ... BEMATORİN-T 0,3 MG + 5 MG/1 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... BİMASOPT %0.03+%0.5 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … BIMATOPROST 1A PH 0.3MG/ML ... BIMAPRESS 0.3 GÖZ DAAMLASI, 1 ADET ... BİMAGAN 0.3 MG/ML GÖZ DAMLASI, 1 ADET …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept …
Matched Description: … Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which ... in 2008, as eyelash growth became a desirable adverse effect for patients using this drug. ... Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. …
Matched Mixtures name: … Bimatoprost/Timolol 1A Pharma 0,3 mg/ml + 5 mg/ml - Augentropfen, Lösung ... BEMATORİN-T 0,3 MG + 5 MG/1 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... BİMASOPT %0.03+%0.5 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … BIMATOPROST 1A PH 0.3MG/ML ... BIMAPRESS 0.3 GÖZ DAAMLASI, 1 ADET ... BİMAGAN 0.3 MG/ML GÖZ DAMLASI, 1 ADET …
Morphine
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Synonyms: … (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol …
Matched Iupac: … (1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15 …
Matched Description: … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk ... [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids ... strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and …
Matched Salts cas: … 335328-17-1 …
Matched Categories: … morphine and antispasmodics …
Matched Products: … MORPH 1 A PHARMA 10MG ... MORPH 1 A PHARMA 30MG ... MORPH 1 A PHARMA 60MG …
Matched Iupac: … (1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15 …
Matched Description: … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk ... [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids ... strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and …
Matched Salts cas: … 335328-17-1 …
Matched Categories: … morphine and antispasmodics …
Matched Products: … MORPH 1 A PHARMA 10MG ... MORPH 1 A PHARMA 30MG ... MORPH 1 A PHARMA 60MG …
Budesonide
Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532]
Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product...
Approved
Matched Description: … Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions ... of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. ... [L10598] It is also available in a combination product with [formoterol].[L10619] …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and budesonide ... salmeterol and budesonide ... formoterol, glycopyrronium bromide and budesonide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BUDESONID 1A PHARMA 64UG ... PULMICORT RESPULES (1 MG IN 2 ML) ... Pulmicort 1 mg - Suspension zur Inhalation …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and budesonide ... salmeterol and budesonide ... formoterol, glycopyrronium bromide and budesonide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BUDESONID 1A PHARMA 64UG ... PULMICORT RESPULES (1 MG IN 2 ML) ... Pulmicort 1 mg - Suspension zur Inhalation …
Displaying drugs 51 - 75 of 891 in total