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Displaying drugs 176 - 200 of 10332 in total

Hydroquinone

Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Hydroquinone 6% ... Hyaluronic Acid Sodium Salt 0.5% / Hydroquinone 4% / Tretinoin 0.05% …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Celazome Fade Shades Lightening Cream w/ Glycolic Acid …

Pentagastrin

A synthetic pentapeptide that mimics the actions of endogenous gastrin when given parenterally. It works by stimulating the secretion of gastric acid, pepsin, and intrinsic factor. It has also been used as a diagnostic aid.
Approved
Matched Iupac: … yl)propanamido]-4-(methylsulfanyl)butanamido]-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}propanoic acid …
Matched Description: … It works by stimulating the secretion of gastric acid, pepsin, and intrinsic factor. …

Rasburicase

Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Approved
Investigational
Matched Categories: … Uric Acid-specific Enzyme …

Coal tar

Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds. It has been...
Approved
Matched Description: … Coal tar is a brown or black liquid of extremely high viscosity. ... Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. …
Matched Mixtures name: … PREPARED COAL TAR 5% ET SALICYLIC ACID 2% OINTMENT ... Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% …

Cyanocobalamin

Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched Mixtures name: … and Succinic Acid ... Folic Acid Plus ... Folic Acid-b12 Tab …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings ... Vitamin B12 and Folic Acid ... iron, vitamin B12 and folic acid …

Agomelatine

Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines Agency (EMA) in 2005. The Committee...
Approved
Investigational

Lapyrium

Lapyrium is a quaternary ammonium cation used as a surfactant, antistatic agent, and biocide in various cosmetic products . It is commonly found formulated as lapyrium chloride.
Approved

Givinostat

Givinostat is a small molecule histone deacetylase (HDAC) inhibitor. It has been investigated as a treatment for a variety of inflammatory diseases, like Crohn's disease and juvenile idiopathic arthritis, cancers like leukemia and lymphoma, as well as several muscular dystrophies. In the context of muscular dystrophy, inhibitors of HDAC appear...
Approved
Investigational

Nedaplatin

Nedaplatin is a second generation platinum analog . It is less nephrotoxic than DB00515 but has proven equally effective. It was approved for use in Japan in 1995.
Approved
Investigational

Sodium tetradecyl sulfate

An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
Approved
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …

Docusate

Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched Iupac: … 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonic acid …
Matched Description: … Docusate can be orally or rectally administered. ... Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation[ ... studies report docusate to be no more effective than placebo for increasing the frequency of stool or …
Matched Mixtures name: … PNV Ferrous Fumarate Docusate Folic Acid ... Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA …

Nizatidine

A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Approved
Matched Description: … A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. …
Matched Categories: … Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …

Fluocinonide

A topical glucocorticoid used in the treatment of eczema.
Approved
Investigational
Matched Mixtures name: … Fluocinonide 0.05% / Hyaluronic Acid Sodium Salt 0.5% / Niacinamide 4% …

Cantharidin

Cantharidin is a naturally occurring odorless, colorless fatty substance of the terpenoid class that is produced as an oral fluid in the alimentary canal of the male blister beetle.[A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin to a female beetle as a copulatory...
Approved
Investigational
Matched Description: … various studies have also investigated the possibility of using cantharidin as an inflammatory model or ... effectiveness at treating topical skin conditions like warts than other commonly available vesicant and/or …
Matched Mixtures name: … Cantharidin 1% / Podophyllum Resin 5% / Salicylic Acid 30% …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Gastric intrinsic factor

Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach that is necessary for the absorption of vitamin B12 (cobalamin) later on in the small intestine. When vitamin B12 is provided in combination with intrinsic factor, intrinsic factor reduces...
Approved
Experimental
Matched Description: … Intrinsic factor is not currently available in any FDA or Health Canada approved products. ... Hematogen in combination with cyanocobalamin (synthetic Vitamin B12), ferrous fumarate, and ascorbic acid …
Matched Mixtures name: … Iron Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Calcium Threonate and Succinic Acid …

Podophyllin

Podophyllin is a resin extracted from the roots of Podophyllum peltatum (American mandrake) and Podophyllum emodi, which contains numerous compounds, amongst which is podophyllin (as well as the drug podophyllotoxin). Podophyllin is the principal active component. Podophyllin arrests mitosis in metaphase.
Approved
Matched Iupac: … 7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-2H,5H,6H,7H,8H-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid …
Matched Mixtures name: … Cantharidin 1% / Podophyllum Resin 5% / Salicylic Acid 30% …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Rabeprazole

Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Description: … It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form ... H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid …
Matched Categories: … Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …

Magnesium oxide

Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Approved
Matched Mixtures name: … Iron Polysaccharides Folic Acid DHA ... Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid …
Matched Categories: … Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …

Pegloticase

Pegloticase is a porcine recombinant PEGylated uricase indicated for the treatment of chronic gout in adult patients that do not respond to other types of therapies. Pegloticase has a similar activity to rasburicase, an enzyme that metabolizes uric acid to allantoin. In gout patients treated with pegloticase, the conversion of...
Approved
Investigational
Matched Description: … uric acid concentrations. ... In gout patients treated with pegloticase, the conversion of uric acid to allantoin leads to lower plasma ... [L42425] Pegloticase has a similar activity to rasburicase, an enzyme that metabolizes uric acid to allantoin …
Matched Categories: … Uric Acid-specific Enzyme ... Compounds used in a research, industrial, or household setting …

Potassium gluconate

Potassium gluconate is a salt of DB01345 and is classified as a food additive by the FDA . It is also used as a potassium supplement . Potassium is an essential nutrient. It is the most abundant cation in the intracellular fluid, where it plays a key role in maintaining...
Approved
Matched Mixtures name: … Potassium W Folic Acid Tab …

Propoxycaine

Propoxycaine is a local anesthetic of the ester type that has a rapid onset of action and a longer duration of action than procaine hydrochloride . This drug was removed from the US market in 1996. Although no longer available in the United States, this medication was used in combination...
Approved

Homatropine methylbromide

Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be...
Approved
Matched Description: … Homatropine is used to treat duodenal or stomach ulcers or intestine problems. ... It can be used together with antacids or other medicine in the treatment of peptic ulcer. …

Sermorelin

Sermorelin acetate is the acetate salt of an amidated synthetic 29-amino acid peptide (GRF 1-29 NH 2 ) that corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone (GHRH or GRF) consisting of 44 amino acid residues
Approved
Withdrawn
Matched Description: … the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone (GHRH or ... GRF) consisting of 44 amino acid residues ... Sermorelin acetate is the acetate salt of an amidated synthetic 29-amino acid peptide (GRF 1-29 NH 2 …

Triheptanoin

Triheptanoin is a source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid oxidation. In clinical trials, patients with long chain fatty acid oxidation disorders (lc-FAODs) treated with triheptanoin are less likely to develop hypoglycemia, cardiomyopathy, rhabdomyolysis, and hepatomegaly.[A214812,A214817] Complications in lc-FAOD patients...
Approved
Investigational
Matched Description: … source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid ... [L14612] In clinical trials, patients with long chain fatty acid oxidation disorders (lc-FAODs) treated …

Rutin

A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Approved
Experimental
Investigational
Matched Mixtures name: … KORDEL`S C TIME ACID FREE C 1000MG TABLET …
Displaying drugs 176 - 200 of 10332 in total