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Displaying drugs 176 - 200 of 917 in total

Pramipexole

Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). It is a non-ergot dopamine agonist drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement) . It was first approved by the FDA in 1997 . Parkinson's Disease is...
Approved
Investigational
Matched Salts name: … Pramipexole hydrochloride …

Olanzapine

Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Salts name: … Olanzapine hydrochloride …

Chloroquine

Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Salts name: … Chloroquine hydrochloride …

Niraparib

Niraparib is an orally active poly (ADP-ribose) polymerase (PARP) inhibitor. By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells. Niraparib is selective towards PARP-1 and PARP-2. First approved by the FDA on March 27, 2017, niraparib is used to treat epithelial ovarian, fallopian tube, or...
Approved
Investigational
Matched Salts name: … Niraparib hydrochloride …

Oxytetracycline

A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Approved
Investigational
Vet approved
Matched Salts name: … Oxytetracycline hydrochloride …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Salts name: … Quinidine hydrochloride …

Infigratinib

Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth. Cholangiocarcinoma is the most common primary malignancy affecting the biliary tract and the second most common primary hepatic malignancy. Infitratinib is a...
Approved
Investigational
Matched Salts name: … Infigratinib hydrochloride …

Methenamine

Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Approved
Vet approved
Matched Salts name: … Methenamine hydrochloride …

Hexaminolevulinate

Hexaminolevulinate is an optical imaging drug. In solution form it is instilled intravesically for use with photodynamic blue light cystoscopy as an adjunct to white light cystoscopy. On May 28, 2010, the U.S. Food and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for Intravesical Solution, Photocure ASA), as...
Approved
Matched Synonyms: … Hexyl 5-amino-4-oxopentanoate hydrochloride ... Pentanoic acid, 5-amino-4-oxo-, hexyl ester, hydrochloride …
Matched Description: … Food and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for …
Matched Salts name: … Hexaminolevulinate hydrochloride …

Bupropion

Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake...
Approved
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Salts name: … Bupropion hydrochloride …
Matched Products: … Bupropion Hydrochloride ... BuPROPion Hydrochloride ... Bupropion hydrochloride …

Oxymorphone

An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia (From Martindale, The Extra Pharmacopoeia,...
Approved
Investigational
Vet approved
Matched Salts name: … Oxymorphone hydrochloride …
Matched Products: … Oxymorphone Hydrochloride ... Oxymorphone hydrochloride ... Oxymorphone Hydrochloride Extended-Release …

Loperamide

Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Mixtures name: … Loperamide Hydrochloride and Simethicone ... Loperamide Hydrochloride, Simethicone ... Loperamide Hydrochloride and Simethicone …
Matched Salts name: … Loperamide hydrochloride …
Matched Products: … Loperamide Hydrochloride ... Loperamide hydrochloride ... LOPERAMIDE HYDROCHLORIDE …

Moexipril

Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Approved
Matched Mixtures name: … Moexipril hydrochloride/hydrochlorothiazide ... Moexipril hydrochloride/hydrochlorothiazide ... Moexipril hydrochloride/hydrochlorothiazide …
Matched Salts name: … Moexipril Hydrochloride …
Matched Products: … Moexipril Hydrochloride ... Moexipril hydrochloride …

Proparacaine

Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
Approved
Vet approved
Matched Description: … It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt. …
Matched Mixtures name: … Fluorescein Sodium and Proparacaine Hydrochloride …
Matched Salts name: … Proparacaine hydrochloride …
Matched Products: … Proparacaine Hydrochloride ... PMS-proparacaine Hydrochloride Oph Soltn 0.5% …

Amantadine

An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and...
Approved
Matched Salts name: … Amantadine hydrochloride …
Matched Products: … Amantadine Hydrochloride ... Amantadine hydrochloride ... Pdp-amantadine Hydrochloride Syrup …

Fexofenadine

Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Mixtures name: … FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE …
Matched Salts name: … Fexofenadine hydrochloride …
Matched Products: … Fexofenadine Hydrochloride ... Fexofenadine hydrochloride ... Fexofenodine Hydrochloride …

Dopamine

One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Approved
Matched Mixtures name: … Dopamine Hydrochloride in Dextrose ... Dopamine Hydrochloride in Dextrose ... Dopamine Hydrochloride in Dextrose …
Matched Salts name: … Dopamine hydrochloride …
Matched Products: … Dopamine Hydrochloride ... DOPamine Hydrochloride ... DOPAMINE HYDROCHLORIDE …

Diethylpropion

A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Salts name: … Diethylpropion hydrochloride …
Matched Products: … Diethylpropion Hydrochloride ... Diethylpropion Hydrochloride ER ... Diethylpropion Hydrochloride Controlled-Release …

Nefazodone

Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb. Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) injury. Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with...
Approved
Withdrawn
Matched Description: … Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb …
Matched Salts name: … Nefazodone hydrochloride …
Matched Products: … Nefazodone hydrochloride ... Nefazodone Hydrochloride …

Clonidine

Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD.[L7237,L7240,L7243,L7246] Clonidine was granted FDA approval on 3 September 1974.
Approved
Matched Salts name: … Clonidine hydrochloride …
Matched Products: … Clonidine Hydrochloride ... Clonidine HYDROCHLORIDE ... Clonidine hydrochloride …

Epirubicin

An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Salts name: … Epirubicin hydrochloride …
Matched Products: … Epirubicin Hydrochloride ... Epirubicin hydrochloride ... EPIRUBICIN HYDROCHLORIDE …

Mepivacaine

A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Approved
Vet approved
Matched Mixtures name: … Mepivacaine Hydrochloride and Levonordefrin ... Mepivacaine Hydrochloride with Levonordefrin …
Matched Salts name: … Mepivacaine hydrochloride …
Matched Products: … Mepivacaine Hydrochloride ... MEPIVACAINE HYDROCHLORIDE 1% ... MEVIPACAINE HYDROCHLORIDE 1% * 5ML …

Trimethobenzamide

Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric...
Approved
Investigational
Matched Salts name: … Trimethobenzamide hydrochloride …
Matched Products: … Trimethobenzamide Hydrochloride ... Trimethobenzamide hydrochloride ... Tigan(r) (trimethobenzamide Hydrochloride) …

Triethylenetetramine

Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, spermidine and spermine. TETA was first developed in Germany in 1861 and its chelating properties were first recognized in 1925. Initially approved by the FDA in 1985...
Approved
Investigational
Matched Salts name: … Trientine hydrochloride …
Matched Products: … Trientine Hydrochloride ... Trientine hydrochloride …

Metformin

Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Mixtures name: … Pioglitazone Hydrochloride and Metformin Hydrochloride ... Pioglitazone Hydrochloride and Metformin Hydrochloride ... Pioglitazone Hydrochloride and Metformin Hydrochloride …
Matched Salts name: … Metformin hydrochloride …
Matched Products: … Metformin Hydrochloride ... Metformin hydrochloride ... Metfomin Hydrochloride …
Displaying drugs 176 - 200 of 917 in total