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Displaying drugs 51 - 75 of 525 in total
Patiromer
Patiromer is a powder for suspension in water for oral administration, approved in the U.S. as Veltassa in October, 2015. Patiromer is supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a non-absorbed potassium-binding polymer, and a calcium-sorbitol counterion. Each gram of patiromer is equivalent to a...
Approved
Investigational
Matched Description: … supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a non-absorbed potassium-binding …
Matched Categories: … Potassium Binder ... Potassium-removing Agents ... Potassium Ion Binding Activity …
Matched Categories: … Potassium Binder ... Potassium-removing Agents ... Potassium Ion Binding Activity …
Tolevamer
Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched Description: … Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. ... It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines …
Matched Salts name: … Tolevamer potassium sodium …
Matched Categories: … Potassium Binder ... Potassium-removing Agents ... Potassium Ion Exchange Activity …
Matched Salts name: … Tolevamer potassium sodium …
Matched Categories: … Potassium Binder ... Potassium-removing Agents ... Potassium Ion Exchange Activity …
Bumetanide
Bumetanide is a sulfamyl diuretic.
Approved
Matched Categories: … bumetanide and potassium ... Non Potassium Sparing Diuretics ... bumetanide and potassium-sparing agents ... Sodium Potassium Chloride Symporter Inhibitors ... High-Ceiling Diuretics and Potassium-Sparing Agents …
Cyclopenthiazide
Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients . It is a positive allosteric modulator at AMPA-A receptors .
Approved
Matched Categories: … cyclopenthiazide and potassium ... cyclopenthiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Sodium bicarbonate
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Mixtures name: … Prismasol 2 mmol/l Potassium ... multiBic® potassium-free Solution for Haemofiltration ... Duosol without Potassium Solution for Haemofiltration …
Magnesium
Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Mixtures name: … Calcium & Magnesium Plus Potassium & Zinc ... Calcium & Magnesium With Potassium & Zinc ... Calcium & Magnesium Plus Potassium & Zinc …
Aminobenzoic acid
A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Approved
Experimental
Matched Description: … The potassium salt is used therapeutically in fibrotic skin disorders. …
Matched Salts name: … Aminobenzoate potassium …
Matched Categories: … aminobenzoate potassium …
Matched Salts name: … Aminobenzoate potassium …
Matched Categories: … aminobenzoate potassium …
Glyburide
Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and...
Approved
Matched Description: … on beta cells, raising intracellular potassium and calcium ion concentrations. ... [L8123] Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels …
Pheneticillin
Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally.
Approved
Matched Salts name: … Pheneticillin potassium …
Cyclothiazide
As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Description: … This results in an increase in potassium excretion via the sodium-potassium exchange mechanism. ... carbonic anhydrases in the smooth muscle or through its action on the large-conductance calcium-activated potassium …
Matched Categories: … cyclothiazide and potassium …
Matched Categories: … cyclothiazide and potassium …
Spironolactone
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … Spironolactone is a potassium-sparing diuretic. ... [A178192] It promotes sodium and water excretion and potassium retention. …
Matched Categories: … Potassium-Sparing Diuretics …
Matched Categories: … Potassium-Sparing Diuretics …
Aluminum zirconium octachlorohydrex gly
Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Matched Description: … The anhydrous form of the compound also has water-absorbing properties. …
Benzoin
Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide, and is used in organic syntheses. This should not be confused with benzoin gum from STYRAX (see DB11222). Benzoin is an FDA-approved colour additive used for marking fruits and vegetables.
Approved
Experimental
Matched Description: … Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide …
Docusate
Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched Salts name: … Docusate potassium …
Ethinylestradiol
Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering. It was developed in an effort to create an estrogen with greater oral bioavailability. These properties were achieved by the substitution of an ethinyl group at carbon 17 of estradiol. Ethinylestradiol soon replaced mestranol in...
Approved
Fludrocortisone
Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Hyoscyamine
Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Glymidine
Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta...
Approved
Investigational
Matched Description: … , reducing potassium conductance and causing depolarization of the membrane. ... Glycodiazine likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface …
Amifampridine
Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium concentrations . It was first discovered in Scotland in the 1970s and its clinical effectiveness for neuromuscular disorders, including Lambert–Eaton myasthenic syndrome (LEMS), has been investigated...
Approved
Investigational
Matched Description: … Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium …
Matched Categories: … Potassium Channel Blockers …
Matched Categories: … Potassium Channel Blockers …
Polythiazide
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Approved
Matched Categories: … polythiazide and potassium …
Gliclazide
Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release...
Approved
Salicylic acid
A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Salts name: … Potassium salicylate …
Matched Categories: … potassium salicylate …
Matched Categories: … potassium salicylate …
Pemirolast
Pemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic...
Approved
Investigational
Matched Description: … Pemirolast potassium is a slightly yellow powder that is soluble in water. …
Matched Salts name: … Pemirolast potassium …
Matched Salts name: … Pemirolast potassium …
Displaying drugs 51 - 75 of 525 in total