Displaying drugs 201 - 225 of 1172 in total
Pibrentasvir
Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets the the viral RNA replication and viron assembly. In combination with DB13879, pibrentastiv is a useful therapy for patients who experienced therapeutic failure from other NS5A inhibitors. In cell cultures, the emergence of amino...
Approved
Investigational
Cisapride
In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias. The FDA issued a warning letter regarding this risk to health care professionals and patients.
Approved
Investigational
Withdrawn
Tipranavir
Tipranavir is a sulfonamide-containing dyhydropyrone and a nonpeptidic protease inhibitor that targets the HIV protease. Tipranavir and ritonavir are coadministered to treat HIV.
Approved
Investigational
Matched Categories: … Sulfur Compounds …
Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Ofloxacin
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Entrectinib
Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. Entrectinib's...
Approved
Investigational
Fluticasone furoate
Fluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label] . Fluticasone furoate was first approved in 2007 .
Approved
Glecaprevir
Glecaprevir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS3/4A protease inhibitor that targets the the viral RNA replication. In combination with DB13878, glecaprevir is a useful therapy for patients who experienced therapeutic failure from other NS3/4A protease inhibitors. It demonstrates a high genetic barrier against resistance...
Approved
Investigational
Matched Categories: … Sulfur Compounds …
Isoflurophate
An irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically. (From Martindale, The Extra Pharmacopoeia, 29th ed, p1330)
Approved
Investigational
Withdrawn
Matched Synonyms: … Diisopropoxyphosphoryl fluoride ... O,O'-diisopropyl phosphoryl fluoride …
Nicotinamide
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Mixtures name: … Niacinamide 4% / Sodium Sulfacetamide Monohydrate 10% / Sulfur Precipitated 2% ... Sulfur ... Phytofortis + Calcium A-D …
Matched Products: … Stem Cell Whitening Serum ... NYAAM NYAAM Mulberry Stem Serum ... Diapia Collagen Goat Milk Ampoule Mask …
Matched Products: … Stem Cell Whitening Serum ... NYAAM NYAAM Mulberry Stem Serum ... Diapia Collagen Goat Milk Ampoule Mask …
Levomefolic acid
Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Description: … It is available commercially as a crystalline form of the calcium salt (Metafolin(R)), which has the …
Matched Mixtures name: … Sodium polysulthionate, 5-methyltetrahydrofolate ... Davimet with Fluoride ... Multivitamin with Fluoride …
Matched Salts name: … Levomefolate calcium …
Matched Products: … L-Methylfolate Calcium …
Matched Mixtures name: … Sodium polysulthionate, 5-methyltetrahydrofolate ... Davimet with Fluoride ... Multivitamin with Fluoride …
Matched Salts name: … Levomefolate calcium …
Matched Products: … L-Methylfolate Calcium …
alpha-Tocopherol succinate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Mixtures name: … Multi-Vitamin Fluoride Drops ... Poly-Vitamin with Fluoride ... Multi-Vitamin Fluoride Drops …
Vitamin D
Vitamin D ultimately comprises a group of lipid-soluble secosteroids responsible for a variety of biological effects, some of which include increasing the intestinal absorption of calcium, magnesium, and phosphate. With reference to human use, there are 2 main forms of vitamin D - vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol)....
Approved
Nutraceutical
Vet approved
Matched Description: … for a variety of biological effects, some of which include increasing the intestinal absorption of calcium ... Vitamin D plays an essential physiological role in maintaining calcium homeostasis and metabolism. ... sufficient quantities of sunlight, vitamin D functions like a hormone on vitamin D receptors to regulate calcium …
Matched Mixtures name: … MVC-Fluoride ... MVC-Fluoride ... MVC-Fluoride …
Matched Mixtures name: … MVC-Fluoride ... MVC-Fluoride ... MVC-Fluoride …
Thiamine
Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Mixtures name: … Phytofortis + Calcium A-D ... Feminique W Iron and Calcium Tab ... Multivit with Fluoride …
Matched Salts name: … Thiamine chloride …
Matched Categories: … Sulfur Compounds …
Matched Salts name: … Thiamine chloride …
Matched Categories: … Sulfur Compounds …
Riboflavin
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. …
Matched Mixtures name: … Phytofortis + Calcium A-D ... Isotonix Calcium Plus Formula ... Feminique W Iron and Calcium Tab …
Matched Salts name: … Riboflavin sodium …
Matched Mixtures name: … Phytofortis + Calcium A-D ... Isotonix Calcium Plus Formula ... Feminique W Iron and Calcium Tab …
Matched Salts name: … Riboflavin sodium …
Folic acid
Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. More specifically, folic acid is required by the body for the synthesis of purines, pyrimidines, and methionine before incorporation into DNA...
Approved
Nutraceutical
Vet approved
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid ... Calcium PNV …
Matched Salts name: … Folate sodium …
Matched Categories: … ferric oxide polymaltose complexes and folic acid …
Matched Salts name: … Folate sodium …
Matched Categories: … ferric oxide polymaltose complexes and folic acid …
alpha-Tocopherol acetate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Matched Mixtures name: … Feminique W Iron and Calcium Tab ... Multivitamin with Fluoride ... Multivitamin with Fluoride …
Tocopherol
Tocopherol exists in four different forms designated as α, β, δ, and γ. They present strong antioxidant activities, and it is determined as the major form of vitamin E. Tocopherol, as a group, is composed of soluble phenolic compounds that consist of a chromanol ring and a 16-carbon phytyl chain....
Approved
Investigational
Matched Mixtures name: … Multivitamin Drops with Fluoride ... Multivitamin Drops with Fluoride ... Multivitamin Drops with Fluoride …
Pantoprazole
Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...
Approved
Matched Salts name: … Pantoprazole sodium …
Matched Categories: … Sulfur Compounds …
Matched Products: … Pantoprazole Sodium ... Pantoprazole sodium ... Pantoprazole Sodium DR …
Matched Categories: … Sulfur Compounds …
Matched Products: … Pantoprazole Sodium ... Pantoprazole sodium ... Pantoprazole Sodium DR …
Dexamethasone
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Mixtures name: … Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% ... Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% / Tretinoin 0.025% …
Matched Salts name: … Dexamethasone sodium phosphate …
Matched Products: … DEXAMETHASONE Sodium Phosphate ... Dexamethasone Sodium Phosphate ... Dexamethasone Sodium Phosphates …
Matched Salts name: … Dexamethasone sodium phosphate …
Matched Products: … DEXAMETHASONE Sodium Phosphate ... Dexamethasone Sodium Phosphate ... Dexamethasone Sodium Phosphates …
Carbamide peroxide
Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and urea. As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. Some adverse effects of carbamide peroxide as a dental bleaching agent include...
Approved
Norflurane
Norflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).
Approved
Experimental
Oteseconazole
Oteseconazole is an azole metalloenzyme inhibitor that targets fungal CYP51. CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound that plays a vital role in the integrity of cell membranes.[L41635,A247020] By binding and inhibiting CYP51, oteseconazole is active against most microorganisms associated with recurrent vulvovaginal...
Approved
Investigational
Cinacalcet
Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Approved
Matched Categories: … Calcium Homeostasis ... Calcium-sensing Receptor Agonist ... Calcium-Regulating Hormones and Agents ... Increased Calcium-sensing Receptor Sensitivity …
Pexidartinib
Pexidartinib is a selective tyrosine kinase inhibitor that works by inhibiting the colony-stimulating factor (CSF1)/CSF1 receptor pathway. Pexidartinib was originally developed by Daiichi Sankyo, Inc. and it was approved by the FDA in August 2019 as the first systemic therapy for adult patients with symptomatic tenosynovial giant cell tumor. Tenosynovial...
Approved
Investigational
Displaying drugs 201 - 225 of 1172 in total