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Accession NumberDB00140  (NUTR00010, APRD00626, EXPT02760, DB09358)
TypeSmall Molecule
GroupsApproved, Nutraceutical, Vet Approved
DescriptionNutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. [PubChem]
Vitamin B2
Vitamin G
External Identifiers Not Available
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
PhotrexaSolution / drops1.46 mg/mLOphthalmicAvedro, Inc.2016-04-15Not applicableUs
Photrexa ViscousSolution / drops1.46 mg/mLOphthalmicAvedro, Inc.2016-04-15Not applicableUs
Riboflavin Inj 50mg/mlSolution50 mgIntramuscular; IntravenousKripps Pharmacy Ltd.1979-12-31Not applicableCanada
Approved Generic Prescription ProductsNot Available
Approved Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
B-2 Caps 100mgCapsule100 mgOralTwin Laboratories Inc.1995-12-311999-11-10Canada
B2 Tab 100mgTablet100 mgOralVita Health Products Inc1979-12-312002-07-31Canada
Riboflavin 5 Phosphate Cap 50mgCapsule50 mgOralThorne Research Canada Ltd.1985-12-312001-07-13Canada
Riboflavin Tab 10mgTablet10 mgOralSwiss Herbal Remedies Ltd.1971-12-311999-09-09Canada
Riboflavin Tab 5mgTablet5 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1957-12-312002-07-31Canada
Riboflavin-S Tab 25mgTablet25 mgOralNutri West Products Ltd.1993-12-311997-08-05Canada
Vit B2 Ctr Srt 200mgTablet, extended release200 mgOralBioenergy Inc.1979-12-311998-06-03Canada
Vita-flavine Cap 100mgCapsule100 mgOralLes Laboratoires Vachon Inc.1991-12-312001-08-07Canada
Vitamin B-2Capsule100 mgOralSisu Inc.2001-09-012006-07-31Canada
Vitamin B-2 50 Mg TabletsTablet50 mgOralGeneral Nutrition Canada Inc.1997-04-182006-08-03Canada
Vitamin B-2 Riboflavin 100mg CapsulesCapsule100 mgOralAlbi Naturals1999-04-302009-07-15Canada
Vitamin B2 100 mgCapsule100 mgOralFlora Manufacturing And Distributing Ltd.2002-03-152004-08-04Canada
Vitamin B2 100mgTablet100 mgOralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
Vitamin B2 Tab 100mgTablet100 mgOralQuest Vitamins A Div Of Purity Life Health Products1978-12-312001-07-06Canada
Vitamin B2 Tab 4mg USP ChewableTablet4 mgOralLab Gernetic Int Ltee1985-12-311997-02-21Canada
Vitamin B2 Tablets 100mgTablet100 mgOralNu Life Nutrition Ltd.1987-12-312005-03-15Canada
Unapproved/Other Products Not Available
International Brands
BisulaseNot Available
Brand mixtures
Active FeGm Pharmaceuticals, Inc.
AlertonicOdan Laboratories Ltd
Allbee With C 550 CapWhitehall Robins Inc.
Allbee With Vitamin C CapWhitehall Robins Inc.
Alsimine W Vitamins A DAlsi Cie Ltee
Am CapsNew Vision Nutritionals Company
AntlervironClassical Remedia Ltd
AppedrineChattem Canada
B 50 CapsulesRheingold Food International Ltd.
B 6 PlusAnabolic Laboratories Inc.
B C Antistress CapLes Laboratoires Bio SantÉ Inc.
B Complex 25mg Vitamin SupplementGarden State Nutritionals
B Complex 50 Vitamin CapBioforce Canada Inc.
B Complex 50+ CapletHealth Wise Nutrition Inc.
B Complex 500 TabNobel Pharm Enr.
B Complex Plus C 300mg TabNutricorp International
B Complex TabletsGolden Neo Life Diamite International, Limited
B Complex W C and B12 InjE L Stickley And Co Ltd.
B Complex W C Forte CapEverest Pharmaceuticals Ltd.
B Complex W Vit C W Non-med Yeast&liver TabPharmavite Llc
B Complex W Vitamin C Fortis CapShoppers Drug Mart Inc.
B Complex With C 300mgVita Health Products Inc
B Complex With C 300mg TabPharmavite Llc
B Complex With C 550mgVita Health Products Inc
B Compound 50mg TabGahler Enterprises Ltd.
B Plus C 300 mgVita Health Products Inc
B Plus C 300mg Timed ReleaseVita Health Products Inc
B Stress C + Iron & ViteStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
B Totum 500Desbergers LtÉe, Division Of Technilab Inc.
B VirolRolmex International Inc.
B Vitamin Compound With B12 ThunasThuna Herbal Remedies Ltd.
B With C 500 CapPharmetics (2011) Inc
B-100 CapsNow Foods
B-100 Complex TabletsViva Pharmaceutical Inc.
B-100 Hi Potency B Vitamins TabNatrol, Inc.
B-100 Vitamin SupplementGarden State Nutritionals
B-2 100mg With C 20mgGahler Enterprises Ltd.
B-50 ComplexVita Health Products Inc
B-50 Complex TabVita Health Products Inc
B-50 Hi Potency B Vitamins TabNatrol, Inc.
B-comboPerdido Key Health And Wellness Inc
B-complexEnrich International
B-complex 100Great Earth Companies, Inc.
B-complex 50Great Earth Companies, Inc.
B-complex TabNature's Sunshine Products Of Canada Ltd.
B-complex TabletsShaklee Canada Inc
B-complex With Vitamin C, Biotin, Folic AcidWn Pharmaceuticals Ltd.
B-complex-50 TabJr Carlson Labs Inc
B-plexWn Pharmaceuticals Ltd.
B-plex 100Merit Pharmaceutical
B-plus - TabChampion's Choice Advanced Nutrition Inc.
B50 B Complex TabNutristar Health Products (1987) Inc.
B50 ComplexPreferred Nutrition Inc.
B6 Plus TabVita Health Products Inc
BacminMarnel Pharmaceuticals, Inc.
Balanced B 125 SrtAnabolic Laboratories Inc.
Balanced B-100 B-complex Vitamins TabPharmavite Llc
Balanced B-100 Timed ReleasePharmavite Llc
Balanced B-50 B-complex Vitamins TabPharmavite Llc
Balanced B-50 B-complex Vitamins, Timed RelePharmavite Llc
Balanced B-50 ComplexLeiner Health Products Inc.
Balanced B-complex Vit + Vit C&e TabPharmavite Llc
Balanced B100Hall Laboratories, Ltd.
Balanced B50 ComplexHall Laboratories, Ltd.
Beautel Supplement De Vitamines Et MineralNobel Pharm Enr.
Beminal W C Fortis InjAyerst Laboratories
Beminal With C Fortis CapWyeth Ayerst Canada Inc.
Beminal With C Fortis PwsWyeth Ayerst Canada Inc.
Bev 29 TabBeverly International Nutrition
Bev B-150Beverly International Nutrition
Bio-fenLisa & Gerry Freundl
Biovim TabLe Naturiste J.M.B. Inc.
BiovitaIldong Pharmaceutical Co., Ltd.
Bugs Bunny and Friends Multiple VitaminsBayer Inc Consumer Care
Bugs Bunny Chew Multi Vit Plus IronMiles Canada Inc. Consumer Health Care Division
C-B ComplexAvacare, Division Of Jeunique International Inc.
C-nate DHACenturion Labs, Llc
C.A.G. TabNutrition For Life International
C.R.T. X Multivitamin & Mineral Powder MixMetaform Ltd.
Carbassist TabletsWyeth Consumer Healthcare Inc.
Cc IIAdded Dimensions
Cda-21 Vitamins With Non-medicinal Probiotic ComplexRx Vitamins Inc.
Cedevita Plus Vitamin SupplementPliva, Pharmaceutical, Chemical, Food And Cosmetic Industry, Inc.
Cedevita Sugar-free Vitamin SupplementPliva, Pharmaceutical, Chemical, Food And Cosmetic Industry, Inc.
Chela Potassium PlusNu Life Nutrition Ltd.
Chela-chromium 200Nu Life Nutrition Ltd.
Chew.multiple Vits.with Extra C for ChildrenRandle Pharmaceutical Inc.
Chewable Multiple Vit Plus Iron for ChildrenRandle Pharmaceutical Inc.
Chewable Multiple Vitamins for ChildrenRandle Pharmaceutical Inc.
Chewable Multiple Vitamins Plus Extra CRandle Pharmaceutical Inc.
Chewable Multiple Vitamins Plus Iron TabRandle Pharmaceutical Inc.
Chewable Multiple Vitamins TabRandle Pharmaceutical Inc.
Chewable MultivitaminsWn Pharmaceuticals Ltd.
Chewable Multivitamins Plus IronWn Pharmaceuticals Ltd.
Children Choice Multivit Chewable TabSwiss Herbal Remedies Ltd.
Children Choice Multivitamin W Iron Chew TabSwiss Herbal Remedies Ltd.
Children's Chewable Multi Vit W IronShoppers Drug Mart Inc.
Children's Chewable Multi VitaminsShoppers Drug Mart Inc.
Children's Chewable Multi Vitamins With Iron TabletsVita Health Products Inc
Children's Chewable Multi-vitaminWn Pharmaceuticals Ltd.
Children's Chewable Multi-vitamin Complete With MineralsWn Pharmaceuticals Ltd.
Children's Chewable Multiple IronStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Children's Chewable Multiple Vitamins - TabStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Children's Chewable Multiple Vitamins (chewable Tablets)Pharmetics (2011) Inc
Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets)Pharmetics (2011) Inc
Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets)Pharmetics (2011) Inc
Children's Vitamins ChewableVita Health Products Inc
Children's Vitamins W Iron ChewableVita Health Products Inc
Childrens Chew Multi Vitamin TabNutristar Health Products (1987) Inc.
Childrens Chewable Multiple VitaminsKsl Pharmaceuticals
Childrens Chewable Multiple Vitamins Plus FeKsl Pharmaceuticals
Childrens Chewable Multiple Vitamins TabPharmavite Llc
Childrens Chewable MultivitaminsRandle Labs Inc.
Childrens Chewable Multivitamins W IronRandle Labs Inc.
Childrens Chewable Vitamin TabPharmetics (2011) Inc
Childrens Chewable VitaminsD.C. Labs Limited
Childrens Multiple Vit and Min Chew TabCountry Health Laboratories Ltd.
Citranatal DHAMission Pharmacal Company
Citranatal RxMission Pharmacal Company
Coenzyme Q10 Isotonix Vitamin and Mineral SupplementMarket America, Inc.
Complete Mega BGahler Enterprises Ltd.
Complete Multivitamins and Minerals Tablets Timed ReleasePharmetics (2011) Inc
Complex 5 - PwrAst Research
Complex-75Frega Inc.
Complexe B 75mgPharmalab Inc.
Complexe B Compose 75Les Laboratoires Bio SantÉ Inc.
Complexe B-75Frega Inc.
Concept DHAUs Pharmaceutical Corporation
Concept ObUs Pharmaceutical Corporation
Croq-vit Pour EnfantsNutrivac Ltee
D'pantothenic Acid-B1-B2 TabHealth Thru Herbs Inc.
Daily Energy Brand B-complexEnzymatic Therapy (Canada) Inc.
Derma-forcePrairie Naturals
Dexatrim TabletsChattem Canada
Dia-viteR & D Laboratories Inc.
DiaplexNephro Tech, Inc.
Dynam Ampoule Et TabletCardinaux Enrg Les Produits Naturels
E & I FormulaeEnrich International
E.S.T. ComplexAbundance Marketing Ltd.
Efferlife Multivitamins and MineralsNaturale Science Inc.
Enviroflex - TabEnviro Tech International Canada
EscaviteGm Pharmaceuticals, Inc.
Essential B TabletsGeneral Nutrition Canada Inc.
Everyday Multiple VitaminsD.C. Labs Limited
Everyday Multiple Vitamins With IronD.C. Labs Limited
Extra P.N. Vitamin-mineral Drink MixChanges International
Ez-flexMetagenics, Inc.
Feminique W Iron and Calcium TabStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Ferra Naka Plus VitaminsNaka Sales Ltd.
Flinstones Multiple Plus IronMiles Canada Inc. Consumer Health Care Division
Flintstones Multiple VitaminsBayer Inc Consumer Care
Flintstones Multiple Vitamins Plus IronBayer Inc Consumer Care
Flintstones Multiple Vitamins TabMiles Canada Inc. Consumer Health Care Division
Flintstones W Extra C TabMiles Canada Inc. Consumer Health Care Division
Floradix Formula LiqFlora Manufacturing And Distributing Ltd.
Floravit - SyrFlora Manufacturing And Distributing Ltd.
FlorivaBon Geo Pharmaceuticals, Inc.
Floriva PlusBon Geo Pharmaceuticals, Inc.
Folcaps Care OneMidlothian Laboratories
Foltabs PrenatalMidlothian Laboratories
For Kids Only Chewable Multivit. Plus IronKsl Pharmaceuticals
For Kids Only Chewable Multivitamins - TabKsl Pharmaceuticals
Formula Adr-vitamin B2,b6 W Calpan TabMetagenics, Inc.
Formula CnBalance Plus, Inc.
Formula D.S.Golden Pride International
Formula Fm Vitamins & Minerals TabMetagenics, Inc.
Formula LfNumark Laboratories, Inc.
Formula OGeneral Nutrition Canada Inc.
Formula O-care Vitamin and Mineral SupplementFor Mor International Inc.
Formula Pro-BBalance Plus, Inc.
Fortamines 10 CapsulesRougier Pharma Division Of Ratiopharm Inc
Fortamines-10 ComprimesRougier Pharma Division Of Ratiopharm Inc
Fortaplex InjKripps Pharmacy Ltd.
Fortistress TabSantÉ Naturelle (Ag) LtÉe
Forty Plus Vitamin SupplementGarden State Nutritionals
Garfield Chewable Multivits Plus Iron TabWhitehall Robins Inc.
Gemvites Jr Tab ChewablePharmavite Laboratories (1987) Inc.
Geritol LiquidGlaxosmithkline Consumer Healthcare Inc.
Gestamine ComprimesLab Nadeau LtÉe, Division Of Technilab Inc.
Gesticare DHAJazz Pharmaceuticals Commercial Corp.
Globucel - MethodeLes Laboratoires Swisse Inc.
Glyco-aide TabAvant Garde, Les SupplÉments
Harvest Of Values All B Complex TabHillestad Pharmaceuticals Usa
Healthy Mamabe Well Rounded Be Well RoundedMATERNAL SCIENCE, LLC
Hemarexin AmpLab Bio Chimique Inc.,Division Of Technilab Pharma Inc.
Hemarexin Liquid and Drinkable AmpoulesSabex Inc
Hemarexin TabLab Bio Chimique Inc.,Division Of Technilab Pharma Inc.
Hemenatal OBWh Nutritionals, Llc
Hi Potency B Complex W Chelated MineralsKlaire Labs Inc.
Hi Potency B52 B Complex TabCountry Health Laboratories Ltd.
Hi Potency Balanced B-100 Complex - TabLeiner Health Products Inc.
Hi Potency Stress B Tension With CLee Adams Laboratories
High Potency Vitamin B Complex + C TabVita Health Products Inc
Hill.viteHillestad Pharmaceuticals Usa
Homosistrol CapsulesMacromed Pharmicia Inc.
Hypo Vites TabPharmetics (2011) Inc
Iberet 500Abbott Laboratories, Limited
IcapsAlcon Canada Inc
Icaps Time ReleaseAlcon Canada Inc
Inatal AdvanceNnodum Pharmaceuticals
Inatal UltraNnodum Pharmaceuticals
Infa Drops MultivitaminsVita Health Products Inc
Infant Multivitamin DropsGeneral Nutrition Canada Inc.
Infantol DropsChurch & Dwight Canada Corp
Insur-all Vitamin SupplementGarden State Nutritionals
Integra PlusUs Pharmaceutical Corporation
Iron 25mg With Vit B-cmplx, Vit C, Cu & MoQuest Vitamins A Div Of Purity Life Health Products
Iron Polysaccharides Folic Acid DHAVirtus Pharmaceuticals LLC
Isotonix Advanced B-complex Vitamins With Potassium and MagnesiumMarket America, Inc.
Isotonix Calcium Plus FormulaMarket America, Inc.
Isotonix Vitamin B-folic Acid-mineral SuppleMarket America, Inc.
Itabs PlusVita Health Products Inc
Kanga Sport Vitamins B & C Plus MineralsLacombe Drugs (1992) Ltd
Kanga-B Vitamin B Group + CLacombe Drugs (1992) Ltd
Kanga-kid Multi-vitamin & MineralLacombe Drugs (1992) Ltd
Kanga-V Multivitamins & MineralsLacombe Drugs (1992) Ltd
Kenwood Liquid SupplementKenwood Laboratories (Division Of Bradley Pharmaceuticals)
Kid's Choice Children's Chewable Vitamins - TabVita Health Products Inc
Kids Stuff TabletsVita Health Products Inc
Kids Stuff With Iron TabletsVita Health Products Inc
Kimchi Vitamin Chewable MultivitaminTobico
KindervitesHerbalife International Of America, Inc.
Leritone JuniorInstitut De Recherche Biologique Yves Ponroy Canada Inc.
Lipo-B-C TabMetagenics, Inc.
Liqui B ComplexTwin Laboratories Inc.
Liqui B Complex PlusTwin Laboratories Inc.
Liqui Infant VitaminsTwin Laboratories Inc.
Liqui VitaTwin Laboratories Inc.
Liquid B Complex 50Jamieson Laboratories Ltd
Livron Plus AmpouleMedic Laboratory LtÉe
Livron Plus TabMedic Laboratory LtÉe
Low Potency B Complex TabFlora Manufacturing And Distributing Ltd.
Lysamine Diet Supp Amp-tabWelcker Lyster Ltd., Division Of Technilab Inc.
M.V.I. 12Aventis Pharma Inc
M.V.I. PaediatricAventis Pharma Inc
M.V.I. PediatricHospira Worldwide, Inc.
Maltlevol 12 LiqCarter Horner Corp.
Maltlevol LiqCarter Horner Corp.
Maxi 10 TabDesbergers LtÉe, Division Of Technilab Inc.
Maxi 6 LiqDesbergers LtÉe, Division Of Technilab Inc.
Mega 13 Multivitamin FormulaVita Health Products Inc
Megavites TabIcn Canada Ltd.
Meplex T 750Medic Laboratory LtÉe
MethaverSterling Knight Pharmaceuticals,Llc
Mini-B TabTwin Laboratories Inc.
Mor-vites TabPharmetics (2011) Inc
Multi - N.T.O.x Formula - TabAbundance Marketing Ltd.
Multi 12 InjectionSandoz Canada Incorporated
Multi BSeroyal International Inc.
Multi Enfants TabVitalab
Multi Nt-OXAbundance Marketing Ltd.
Multi RolRolmex International Inc.
Multi Vitamin - MineralEnrich International
Multi Vitamin & MineralsWn Pharmaceuticals Ltd.
Multi Vitamin and FluorideLibertas Pharma, Inc.
Multi Vitamin Drops With FluorideSeton Pharmaceuticals
Multi Vitamin Drops With Fluoride and IronSeton Pharmaceuticals
Multi Vitamin Drops With Fluoride With IronStratus Pharmaceuticals
Multi Vitamin Plus IronWn Pharmaceuticals Ltd.
Multi Vitamin With FluorideQualitest Pharmaceuticals
Multi Vitamin-mineral FormulaVita Health Products Inc
Multi Vitamin, Iron and FluorideLibertas Pharma, Inc.
Multi Vitamines - LiqLand Art Inc.
Multi Vitamins & MineralsWn Pharmaceuticals Ltd.
Multi Vite Liq AdultPharmetics (2011) Inc
Multi Vite Liq JuniorPharmetics (2011) Inc
Multi-11Sandoz Canada Incorporated
Multi-12 PediatricSabex Inc
Multi-12/k1 PediatricSandoz Canada Incorporated
Multi-min Electro C Pow Plus B2Quest Vitamins A Div Of Purity Life Health Products
Multi-vit With FluorideA S Medication Solutions Llc
Multi-vit With Fluoride and IronQualitest Pharmaceuticals
Multi-vitaminLLC Federal Solutions
Multi-vitamin Dietary SupplementGarden State Nutritionals
Multi-vitamin FluorideStratus Pharmaceuticals
Multi-vitamin Fluoride and Iron DropsBoca Pharmacal, LLC
Multi-vitamin Fluoride DropsH.J. Harkins Company, Inc.
Multi-vitamin With FluorideGolden State Medical Supply, Inc.
Multi-vitamines Enfants ComprimeHerbes Universelles Inc.
Multi-vitaminsWn Pharmaceuticals Ltd.
Multi-vitamins With MineralsWn Pharmaceuticals Ltd.
Multiple Vitamin Plus Minerals TabHall Laboratories, Ltd.
Multiple Vitamin TabAdams Labs Ltd.
Multiple VitaminsGfr Pharma Ltd.
Multiple Vitamins and Minerals TabRandle Labs Inc.
Multiple Vitamins Plus Iron for WomenPharmetics (2011) Inc
Multiple Vitamins Plus Iron TabHall Laboratories, Ltd.
Multiple Vitamins TabHall Laboratories, Ltd.
Multiple Vitamins W Iron TabStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Multiple Vitamins W Minerals TabStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Multiple Vitamins With IronStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Multiple Vitamins With Minerals TabletsPharmetics (2011) Inc
MultisolLes Laboratoires Vachon Inc.
Multivit-liqPharmalab Inc.
MultivitaminLaboratoires Confab Inc
Multivitamin With FluorideSancilio & Company Inc
MultivitaminesRolmex International Inc.
Multivitamines Et MinerauxLe Groupe M. Vachon Inc.
Multivitamines Plus Fer Pour Enfants (chewable Tablets)Laboratoire Lalco Inc.
Multivitamines Pour Enfants (chewable Tablets)Laboratoire Lalco Inc.
MultivitaminsVita Health Products Inc
Multivitamins for ChildrenQuest Vitamins A Div Of Purity Life Health Products
Multivitamins W IronRandle Labs Inc.
MvcSancilio & Company Inc
Mvc-fluorideSancilio & Company Inc.
Myhephron Dialysis and Stress SupplementMartin Ekwealor Pharmaceu
Mynephrocaps Dialysis/stress Vitamin SupplementMartin Ekwealor Pharmaceuticals, Inc.
Nata KompleteWh Nutritionals, Llc
NatafortMission Pharmacal Company
NataviteSchein Pharmaceutical Canada Inc.
Neo Bex ElixirNeolab Inc
Neo Vites TabNeolab Inc
Neo-bexNeolab Inc
Neo-bex InjectableBrostel Inc.
Neo-vites & Minerals TabNeolab Inc
NephrocapsCardinal Health
Nutrifer Plus TabletsWyeth Ayerst Canada Inc.
Nutrilite Double XNutrilite, A Division Of Access Business Group, Llc
Nutrol-B-complexRolmex International Inc.
O-cal Fa MultivitaminPharmics, Inc.
O-cal Prenatal VitaminPharmics, Inc.
OnccorSimone Protective Pharmaceuticals, Inc.
One A Day Advance AdultsBayer Inc Consumer Care
One A Day Advance Adults 50+Bayer Inc Consumer Care
One A Day Advance FemBayer Inc Consumer Care
One A Day TabCountry Health Laboratories Ltd.
Orange Flavored Crystal Chews TabJeunique International Inc.
Orifer FSanofi Aventis Canada Inc
Original Bioscal Forte Multi-vitamin Supplement CapsulesCarram Inc.
Orti BSeroyal International Inc.
P.N.P. Vitamin DrinkChanges International
P.R.O. ComplexAbundance Marketing Ltd.
Paramettes Chewable Multivitamins Plus IronWyeth Ayerst Canada Inc.
Paramettes Chewable Multivits With Iron TabWhitehall Robins Inc.
Paramettes Multivits Plus Iron Tab (teens)Whitehall Robins Inc.
Paramettes SyrupWyeth Ayerst Canada Inc.
Permathene-12 - CapletCCA Industries, Inc.
Phosthenine Vitamines Et Fer (ampoules Buvable)Laboratoires Cortunon Inc.
Phytofortis + Calcium A-DProduits Phyto Inc.
Phytoplex B LiqProduits Phyto Inc.
PhytopureLaboratoire Lalco Inc.
PM CapsNew Vision Nutritionals Company
PNF-FirstAcella Pharmaceuticals, LLC
Pnv Ferrous Fumarate Docusate Folic AcidVirtus Pharmaceuticals LLC
Pnv Prenatal Plus MultivitaminSancilio & Company Inc
Pnv Prenatal VitaminSancilio & Company Inc
Pnv Prenatal Vitamin Plus Vitamin ASancilio & Company Inc
Pnv-selectAcella Pharmaceuticals, LLC
Poly-VI-sol DropsMead Johnson Nutritionals
Polymine Avec Zinc Et CuivreLes Laboratoires Vachon Inc.
Prefera Ob Plus DHAAlaven Pharmaceutical LLC
PreferaobMEDA Pharmaceuticals
Preferaob Plus DHAAlaven Pharmaceutical LLC
PregvitDuchesnay Inc
Pregvit Folic 4Duchesnay Inc
Pregvit Folic 5Duchesnay Inc
Prenatal 19Nationwide Laboratories, LLC
Prenatal Mega AntioxidantUsana Health Services, Inc.
Prenatal PlusBlenheim Pharmacal, Inc.
Prenatal Plus IronMajor Pharmaceuticals
Prenatal Vitamins Plusbryant ranch prepack
Prenatal Vitamins Plus Low IronPatrin Pharma, Inc.
Prenate EliteAvion Pharmaceuticals, Llc
Prenate StarAvion Pharmaceuticals, Llc
PreplusVirtus Pharmaceuticals LLC
PretabVirtus Pharmaceuticals LLC
Prevital TabBio Vita
Purevit Dualfe PlusPure Tek Corporation
Q.T. Vitamin and Mineral Drink MixGarden State Nutritionals
Reaphirm Plant Source DHAEverett Laboratories, Inc.
Reno CapsNnodum Pharmaceuticals
ReplaviteStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Revit Plus CapIcn Canada Ltd.
Revit TabIcn Canada Ltd.
Revitex Ampoules Et ComprimesLes Produits Gerbex Inc.
Revival 1 TabBio Vita
Right Choice A.M. Multi Formula - CapletBody Wise International Llc
Se-natal 19Seton Pharmaceuticals
Se-natal 19 ChewableSeton Pharmaceuticals
Se-natal OneSeton Pharmaceuticals
Se-tan PlusSeton Pharmaceuticals
Sibergin B - CapPharmavite Llc
Somarexin and C 1000Laboratoire Lalco Inc.
Somavit Brand Vitamins and Minerals ComplexSoma Health Products
Sopalamine/3b Plus CTechnilab Pharma Inc.
Spectrum 2 CapNf Formulas Inc.
Stress B & C CapletHealth Wise Nutrition Inc.
Stress B Capsules With Vitamin CRheingold Food International Ltd.
Stress B Complex With C, E & IronPharmavite Llc
Stress B With 1000 Mg Vitamin CHolista Health (Canada) Inc.
Stress B&c TabBioforce Canada Inc.
Stress Complex 600 Avec Vit E Cuivre ZincFrega Inc.
Stress Ctr SrtBioenergy Inc.
Stress FormulaVita Health Products Inc
Stress Formula + IronVita Health Products Inc
Stress Formula B-comp + 500mg Vit C TabQuest Vitamins A Div Of Purity Life Health Products
Stress Formula Multi-B Comp + 500mg Vit C CapQuest Vitamins A Div Of Purity Life Health Products
Stress Formula Multivitamin Tablets USPLeiner Health Products Inc.
Stress Formula TabNature's Sunshine Products Of Canada Ltd.
Stress Formula Vit B With C ComplexWatkins Incorporated
Stress Forte Plus Lipotropic FactorsDouglas Laboratories
Stress TabVita Health Products Inc
Stress TabletsD.C. Labs Limited
Stress Vitamin B With C Complex TabletsPurity Life Health Products A Division Of Sunopta Inc.
StressmatesTwin Laboratories Inc.
Strovite Forte CapletEverett Laboratories, Inc.
Strovite One CapletsEverett Laboratories, Inc.
Sun-rype VitaburstSun Rype Products Ltd.
Super B Compound W 500mg Vit CGahler Enterprises Ltd.
Super Charged EnergySimone Protective Pharmaceuticals, Inc.
Super Daily No 2W.R. Enterprises Inc.
Super PantoplexNu Life Nutrition Ltd.
Super Stress CapsulesRheingold Food International Ltd.
Super Stress Mega B Plus 1000mg Vit C TabQuest Vitamins A Div Of Purity Life Health Products
Super Vitalex Ampoule BuvableCarmaran LtÉe
Super-pote Vitamin SupplementGarden State Nutritionals
Supplement De Multivitamines Infusion Arome Fruits RougesYves Rocher Inc.
Supravite 10ml AmpouleNobel Pharm Enr.
Supravite Bouteille 250mlNobel Pharm Enr.
Supravite C 1000Nobel Pharm Enr.
Supravite Pour EnfantsPharmalab Inc.
Supravite Stress Avec Vit EPharmalab Inc.
Supravite Stress Avec Vit E Cuivre Et ZincPharmalab Inc.
Supravite Stress Avec Vit E Et FerPharmalab Inc.
Surbex 500 FilmtabAbbott Laboratories, Limited
Surbex-500 With IronAbbott Laboratories, Limited
Surbex-500 With ZincAbbott Laboratories, Limited
Swical-energy-2Les Laboratoires Swisse Inc.
T.R.I. B-plex SrcAnabolic Laboratories Inc.
Tandem ObUs Pharmaceutical Corporation
Tandem PlusUs Pharmaceutical Corporation
Tender Age Multi VitaminsJamieson Laboratories Ltd
Time Release B 100 Compound - TabletHealth Wise Nutrition Inc.
Timed Release B Complex 100 SrtJamieson Laboratories Ltd
Timed Release B-complex 100Great Earth Companies, Inc.
Timed Release B-complex 50Great Earth Companies, Inc.
Tini-cal AmpoulesPharmetics (2011) Inc
Toni Com LiqVitalab
Tonicol Et A-D-C Ampoules/comprimesDistributions Multi Pro Inc.
Tonimol Cap LiqHerbes Universelles Inc.
TriadvanceTrigen Laboratories, Inc.
Tricare PrenatalMedecor Pharma, Llc
Trinatal GtTrigen Laboratories, Inc.
Twin Ultra Liquid Fruit Punch FlavorTwin Laboratories Inc.
Twin Ultra Liquid Grape FlavorTwin Laboratories Inc.
Twin Ultra Liquid Lemon-lime FlavorTwin Laboratories Inc.
Twin Ultra Liquid Orange FlavorTwin Laboratories Inc.
Ultimatecare One NfTrigen Laboratories, Inc.
Ultra EnerforceNutribon (1986) Inc.
Ultra HrNatural Organics Inc.
Usana Megavitamin Tablets - TabUsana Health Sciences Inc.
V-natalVirtus Pharmaceuticals
Vasodyn TabNutri Dyn Products Ltd.
Viamon Ampoules Et ComprimesLab Nadeau LtÉe, Division Of Technilab Inc.
Vigo Multivitamins Drops/lozengeAshbury Research Corporation
Vimeral TabIcn Canada Ltd.
Virt-bal DHA PlusVirtus Pharmaceuticals
Virt-capsVirtus Pharmaceuticals LLC
Virt-PNVirtus Pharmaceuticals
Virt-vite PlusVirtus Pharmaceuticals LLC
Vit B Complex CtrBioenergy Inc.
Vit B Complex Plus Vit C 550mgHall Laboratories, Ltd.
Vit-HA Multi Vitamin and Zinc SupplementRheingold Food International Ltd.
Vita B + C 500 TabLaboratoire Romilo
Vita B Complex TabNutrimetics International (Canada) Inc.
Vita Day TabJamieson Laboratories Ltd
Vita-BNutri Dyn Products Ltd.
Vita-B-75 CapLes Laboratoires Vachon Inc.
Vita-worth B-complex TabletsGeneral Nutrition Canada Inc.
Vitabanks Vitamin TabVitabank Inc.
Vitachrom GcNikken Usa, Incorporated
Vitaday TabPharmetics (2011) Inc
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Riboflavin 5'-phosphate sodium
  • Monoisotopic Mass: 514.10768889
  • Average Mass: 514.36
Riboflavin 5'-phosphate sodium anhydrous
  • Monoisotopic Mass: 478.08655952
  • Average Mass: 478.33
CAS number83-88-5
WeightAverage: 376.3639
Monoisotopic: 376.138284392
Chemical FormulaC17H20N4O6
CC1=C(C)C=C2N(C[[email protected]](O)[[email protected]](O)[[email protected]](O)CO)C3=NC(=O)NC(=O)C3=NC2=C1
IndicationFor the treatment of ariboflavinosis (vitamin B2 deficiency).
Structured Indications
PharmacodynamicsRiboflavin or vitamin B2 is an easily absorbed, water-soluble micronutrient with a key role in maintaining human health. Like the other B vitamins, it supports energy production by aiding in the metabolising of fats, carbohydrates, and proteins. Vitamin B2 is also required for red blood cell formation and respiration, antibody production, and for regulating human growth and reproduction. It is essential for healthy skin, nails, hair growth and general good health, including regulating thyroid activity. Riboflavin also helps in the prevention or treatment of many types of eye disorders, including some cases of cataracts.
Mechanism of actionBinds to riboflavin hydrogenase, riboflavin kinase, and riboflavin synthase. Riboflavin is the precursor of flavin mononucleotide (FMN, riboflavin monophosphate) and flavin adenine dinucleotide (FAD). The antioxidant activity of riboflavin is principally derived from its role as a precursor of FAD and the role of this cofactor in the production of the antioxidant reduced glutathione. Reduced glutathione is the cofactor of the selenium-containing glutathione peroxidases among other things. The glutathione peroxidases are major antioxidant enzymes. Reduced glutathione is generated by the FAD-containing enzyme glutathione reductase.
TargetKindPharmacological actionActionsOrganismUniProt ID
Riboflavin kinaseProteinyes
HumanQ969G6 details
Riboflavin synthaseProteinyes
Escherichia coli (strain K12)P0AFU8 details
Flavin reductase (NADPH)Proteinyes
product of
HumanP30043 details
Related Articles
AbsorptionVitamin B2 is readily absorbed from the upper gastrointestinal tract.
Volume of distributionNot Available
Protein binding60%


Route of eliminationNot Available
Half life66-84 minutes
ClearanceNot Available
ToxicityNot Available
Affected organisms
  • Humans and other mammals
PathwayCategorySMPDB ID
Riboflavin MetabolismMetabolicSMP00070
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
Drug Interactions
DrugInteractionDrug group
PorfimerRiboflavin may increase the photosensitizing activities of Porfimer.Approved, Investigational
VerteporfinRiboflavin may increase the photosensitizing activities of Verteporfin.Approved, Investigational
Food InteractionsNot Available
Synthesis Reference

Hansgeorg Ernst, Wolfram Schmidt, Joachim Paust, “Preparation of riboflavin.” U.S. Patent US4567261, issued August, 1958.

General References
  1. Zempleni J, Galloway JR, McCormick DB: Pharmacokinetics of orally and intravenously administered riboflavin in healthy humans. Am J Clin Nutr. 1996 Jan;63(1):54-66. [PubMed:8604671 ]
External Links
ATC CodesA11HA04
AHFS CodesNot Available
PDB Entries
FDA labelNot Available
MSDSDownload (39.4 KB)
Predicted ADMET features
Human Intestinal Absorption+0.9156
Blood Brain Barrier-0.8495
Caco-2 permeable-0.7122
P-glycoprotein substrateSubstrate0.7414
P-glycoprotein inhibitor INon-inhibitor0.8708
P-glycoprotein inhibitor IINon-inhibitor0.9466
Renal organic cation transporterNon-inhibitor0.9279
CYP450 2C9 substrateNon-substrate0.7819
CYP450 2D6 substrateNon-substrate0.8435
CYP450 3A4 substrateNon-substrate0.522
CYP450 1A2 substrateInhibitor0.8531
CYP450 2C9 inhibitorNon-inhibitor0.9071
CYP450 2D6 inhibitorNon-inhibitor0.9516
CYP450 2C19 inhibitorInhibitor0.7302
CYP450 3A4 inhibitorNon-inhibitor0.8309
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9203
Ames testNon AMES toxic0.804
BiodegradationNot ready biodegradable0.9641
Rat acute toxicity1.6067 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9395
hERG inhibition (predictor II)Non-inhibitor0.5362
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
ManufacturersNot Available
Dosage forms
Tablet, extended releaseOral
Injection, solutionIntramuscular; Intravenous
Powder, for solutionIntramuscular; Intravenous
Powder, for solutionIntravenous
Tablet, effervescentOral
LiquidIntramuscular; Intravenous
Injection, powder, lyophilized, for solutionIntravenous
Liquid; tabletOral
Solution / dropsOral
Granule, effervescentOral
Tablet, chewableOral
SolutionIntramuscular; Intravenous
Solution / dropsOphthalmic1.46 mg/mL
Tablet, coatedOral
CapsuleOral50 mg
SolutionIntramuscular; Intravenous50 mg
TabletOral10 mg
TabletOral5 mg
TabletOral25 mg
Capsule, extended releaseOral
Capsule; liquidOral
Tablet, extended releaseOral200 mg
CapsuleOral100 mg
Capsule, gelatin coatedOral
Capsule, liquid filledOral
TabletOral50 mg
TabletOral100 mg
TabletOral4 mg
Tablet, film coatedOral
Unit descriptionCostUnit
Riboflavin powder0.44USD g
Riboflavin 100 mg tablet0.09USD tablet
Riboflavin 50 mg tablet0.08USD tablet
Vitamin b-2 50 mg tablet0.08USD tablet
Ribo 100 mg tablet0.04USD tablet
Vitamin b-2 25 mg tablet0.02USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
PatentsNot Available
Experimental Properties
melting point280 dec °CPhysProp
water solubility84.7 mg/L (at 25 °C)YALKOWSKY,SH & DANNENFELSER,RM (1992)
logP-1.46HANSCH,C ET AL. (1995)
logS-3.68ADME Research, USCD
pKa10.2BUDAVARI,S ET AL. (1996)
Predicted Properties
Water Solubility0.657 mg/mLALOGPS
pKa (Strongest Acidic)6.97ChemAxon
pKa (Strongest Basic)0.76ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count9ChemAxon
Hydrogen Donor Count5ChemAxon
Polar Surface Area155.05 Å2ChemAxon
Rotatable Bond Count5ChemAxon
Refractivity96.27 m3·mol-1ChemAxon
Polarizability37.5 Å3ChemAxon
Number of Rings3ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Mass Spec (NIST)Download (11.3 KB)
Spectrum TypeDescriptionSplash Key
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-004i-0019000000-86365dedafa031aa7787View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-0006-4390000000-ac1b59ab7cc2209f4241View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-00dj-4900000000-72d33eb27b9bd6a13d9eView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Positivesplash10-004l-0569000000-874b71fdc78d04853bf0View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Negativesplash10-0a4i-0091000000-a82c54d3153103fcdb1fView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, NegativeNot Available
1D NMR1H NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
DescriptionThis compound belongs to the class of organic compounds known as flavins. These are compounds containing a flavin (7,8-dimethyl-benzo[g]pteridine-2,4-dione) moiety, with a structure characterized by an isoalloaxzine tricyclic ring.
KingdomOrganic compounds
Super ClassOrganoheterocyclic compounds
ClassPteridines and derivatives
Sub ClassAlloxazines and isoalloxazines
Direct ParentFlavins
Alternative Parents
  • Flavin
  • Quinoxaline
  • Hydroxypyrimidine
  • Pyrimidone
  • Benzenoid
  • Pyrimidine
  • Pyrazine
  • Heteroaromatic compound
  • Secondary alcohol
  • Polyol
  • 1,2-diol
  • Azacycle
  • Hydrocarbon derivative
  • Primary alcohol
  • Organooxygen compound
  • Organonitrogen compound
  • Alcohol
  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External Descriptors


Pharmacological action
General Function:
Riboflavin kinase activity
Specific Function:
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH...
Gene Name:
Uniprot ID:
Molecular Weight:
17623.08 Da
  1. Werner R, Manthey KC, Griffin JB, Zempleni J: HepG2 cells develop signs of riboflavin deficiency within 4 days of culture in riboflavin-deficient medium. J Nutr Biochem. 2005 Oct;16(10):617-24. [PubMed:16081269 ]
  2. Solovieva IM, Kreneva RA, Errais Lopes L, Perumov DA: The riboflavin kinase encoding gene ribR of Bacillus subtilis is a part of a 10 kb operon, which is negatively regulated by the yrzC gene product. FEMS Microbiol Lett. 2005 Feb 1;243(1):51-8. [PubMed:15668000 ]
  3. Ishchuk OP, Iatsyshyn VIu, Dmytruk KV, Voronovs'kyi AIa, Fedorovych DV, Sybirnyi AA: [Construction of the flavinogenic yeast Candida famata strains with high riboflavin kinase activity using gene engineering]. Ukr Biokhim Zh (1999). 2006 Sep-Oct;78(5):63-9. [PubMed:17290783 ]
  4. Sandoval FJ, Roje S: An FMN hydrolase is fused to a riboflavin kinase homolog in plants. J Biol Chem. 2005 Nov 18;280(46):38337-45. Epub 2005 Sep 23. [PubMed:16183635 ]
  5. Bertollo CM, Oliveira AC, Rocha LT, Costa KA, Nascimento EB Jr, Coelho MM: Characterization of the antinociceptive and anti-inflammatory activities of riboflavin in different experimental models. Eur J Pharmacol. 2006 Oct 10;547(1-3):184-91. Epub 2006 Jul 26. [PubMed:16962092 ]
  6. Hirano G, Izumi H, Yasuniwa Y, Shimajiri S, Ke-Yong W, Sasagiri Y, Kusaba H, Matsumoto K, Hasegawa T, Akimoto M, Akashi K, Kohno K: Involvement of riboflavin kinase expression in cellular sensitivity against cisplatin. Int J Oncol. 2011 Apr;38(4):893-902. doi: 10.3892/ijo.2011.938. Epub 2011 Feb 9. [PubMed:21308351 ]
Escherichia coli (strain K12)
Pharmacological action
General Function:
Riboflavin synthase activity
Specific Function:
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Gene Name:
Uniprot ID:
Molecular Weight:
23444.77 Da
  1. Kim RR, Illarionov B, Joshi M, Cushman M, Lee CY, Eisenreich W, Fischer M, Bacher A: Mechanistic insights on riboflavin synthase inspired by selective binding of the 6,7-dimethyl-8-ribityllumazine exomethylene anion. J Am Chem Soc. 2010 Mar 10;132(9):2983-90. doi: 10.1021/ja908395r. [PubMed:20143812 ]
  2. Long Q, Ji L, Wang H, Xie J: Riboflavin biosynthetic and regulatory factors as potential novel anti-infective drug targets. Chem Biol Drug Des. 2010 Apr;75(4):339-47. doi: 10.1111/j.1747-0285.2010.00946.x. Epub 2010 Feb 8. [PubMed:20148904 ]
Pharmacological action
product of
General Function:
Riboflavin reductase (nadph) activity
Specific Function:
Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.
Gene Name:
Uniprot ID:
Molecular Weight:
22119.215 Da
  1. Russell TR, Demeler B, Tu SC: Kinetic mechanism and quaternary structure of Aminobacter aminovorans NADH:flavin oxidoreductase: an unusual flavin reductase with bound flavin. Biochemistry. 2004 Feb 17;43(6):1580-90. [PubMed:14769034 ]
  2. van Pee KH, Patallo EP: Flavin-dependent halogenases involved in secondary metabolism in bacteria. Appl Microbiol Biotechnol. 2006 May;70(6):631-41. Epub 2006 Mar 17. [PubMed:16544142 ]


Pharmacological action
General Function:
Serotonin binding
Specific Function:
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.
Gene Name:
Uniprot ID:
Molecular Weight:
59681.27 Da
  1. Strolin Benedetti M, Tipton KF, Whomsley R: Amine oxidases and monooxygenases in the in vivo metabolism of xenobiotic amines in humans: has the involvement of amine oxidases been neglected? Fundam Clin Pharmacol. 2007 Oct;21(5):467-80. [PubMed:17868200 ]
Pharmacological action
General Function:
Protein complex binding
Specific Function:
Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.
Gene Name:
Uniprot ID:
Molecular Weight:
74595.895 Da
  1. Bates CJ, Fuller NJ: The effect of riboflavin deficiency on methylenetetrahydrofolate reductase (NADPH) (EC and folate metabolism in the rat. Br J Nutr. 1986 Mar;55(2):455-64. [PubMed:3676170 ]
  2. Macdonald HM, McGuigan FE, Fraser WD, New SA, Ralston SH, Reid DM: Methylenetetrahydrofolate reductase polymorphism interacts with riboflavin intake to influence bone mineral density. Bone. 2004 Oct;35(4):957-64. [PubMed:15454103 ]


Pharmacological action
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-in...
Gene Name:
Uniprot ID:
Molecular Weight:
61815.78 Da
  1. Kuze K, Graves P, Leahy A, Wilson P, Stuhlmann H, You G: Heterologous expression and functional characterization of a mouse renal organic anion transporter in mammalian cells. J Biol Chem. 1999 Jan 15;274(3):1519-24. [PubMed:9880528 ]
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Drug created on June 13, 2005 07:24 / Updated on December 08, 2016 11:48