Psychostimulants, Agents Used for ADHD and Nootropics

Name
Psychostimulants, Agents Used for ADHD and Nootropics
Accession Number
DBCAT002180
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
AmphetamineA CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
CaffeineA stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
MethylphenidateA stimulant used in the management of Attention Deficit Hyperactivity Disorder (ADHD).
ModafinilA stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder.
PemolineA central nervous system (CNS) stimulant that was previously used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy.
LisdexamfetamineA central nervous system (CNS) stimulant used to treat attention deficit hyperactivity disorder (ADHD) and moderate to severe eating disorders.
FencamfaminFor the the treatment of depressive fatigue in convalescence and other debilitated states as well as in the treatment of depressive day-time fatigue, lack of concentration and lethargy.
DextroamphetamineA sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
MetamfetamineA sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity.
AniracetamA nootropic drug used to ameliorate memory and attention disturbances accompanying cerebrovascular diseases and degenerative brain disorders.
ArmodafinilA stimulant used to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea, narcolepsy, or shift work disorder.
PropentofyllineInvestigated for use/treatment in alzheimer's disease.
DexmethylphenidateA norepinephrine-dopamine reuptake inhibitor used in the treatment of ADHD in conjunction with other therapies.
AcetylcarnitineAn acetylated form of the amino acid derivative L-carnitine that assists in mitochondrial fatty acid metabolism. It is under investigation as a treatment for numerous conditions, including neuropathy, depression, and dementia.
AdrafinilUsed to relieve excessive sleepiness and inattention in elderly patients.
IdebenoneAn analogue of ubiquinone used for the treatment of visual impairment in adolescent and adult patients with Leber’s Hereditary Optic Neuropathy (LHON).
PiracetamA nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer.
PipradrolA central nervous stimulant ingredient in a product used to treat functional fatigue.
VinpocetineA synthetic derivative of a vinca alkaloid used to treat neurological symptoms of cerebrovascular disease.
PyritinolA vitamin B6 analog indicated as an adjunct therapy in the treatment of a wide variety of disorders of the brain.
PramiracetamPramiracetam has been previously approved in some eastern European countries under the brand names Pramistar, Neupramir, and Remen. It was also previously approved in the United States with orphan drug...
FenozoloneNot Annotated
DeanolDeanol is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA). It holds tertiary amine and primary alcohol groups as functional groups. Deanol has been used in the treatment...
PirisudanolNot Annotated
ProlintaneNot Annotated
PhenibutNot Annotated
NizofenoneNot Annotated
OxiracetamNot Annotated
MeclofenoxateNot Annotated
FipexideNot Annotated
LinopirdineNot Annotated
FenethyllineNot Available
CiticolineAn endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects.
AtomoxetineA selective norepinephrine reuptake inhibitor (SNRI) used in the management of Attention Deficit Hyperactivity Disorder (ADHD).
SolriamfetolSolriamfetol is indicated for treatment of daytime sleepiness associated with obstructive sleep apnea and narcolepsy, but is not a treatment for the underlying airway obstruction in apnea patients[FDA Label][A176534,A176744].
SerdexmethylphenidateA prodrug of the CNS stimulant dexmethylphenidate used as a first-line treatment for Attention Deficit Hyperactivity Disorder (ADHD).
Drugs & Drug Targets
DrugTargetType
AmphetamineSodium-dependent dopamine transportertarget
AmphetamineCocaine- and amphetamine-regulated transcript proteintarget
AmphetamineTrace amine-associated receptor 1target
AmphetamineCytochrome P450 2D6enzyme
AmphetamineSolute carrier family 22 member 3transporter
AmphetamineSolute carrier family 22 member 5transporter
AmphetamineSynaptic vesicular amine transportertarget
AmphetamineCytochrome P450 2A6enzyme
AmphetamineSodium-dependent noradrenaline transportertarget
AmphetamineAlpha adrenergic receptortarget
AmphetamineBeta adrenergic receptortarget
AmphetamineDopamine D2 receptortarget
AmphetamineAmine oxidase [flavin-containing] Btarget
AmphetamineSodium-dependent serotonin transportertarget
AmphetamineMonoamine oxidasetarget
CaffeineAdenosine receptor A1target
CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
CaffeineAdenosine receptor A2atarget
CaffeineCytochrome P450 1A2enzyme
CaffeineRyanodine receptor 1target
CaffeineCytochrome P450 3A4enzyme
CaffeineCytochrome P450 2E1enzyme
CaffeineCytochrome P450 2C8enzyme
CaffeineCytochrome P450 2C9enzyme
CaffeineCytochrome P450 1A1enzyme
CaffeineCytochrome P450 1B1enzyme
CaffeineCytochrome P450 2D6enzyme
CaffeineCyclic nucleotide phosphodiesterasetarget
CaffeineDNA-dependent protein kinase catalytic subunittarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
CaffeineInositol 1,4,5-trisphosphate receptortarget
CaffeineSerine-protein kinase ATMtarget
CaffeineATP-binding cassette sub-family G member 2transporter
CaffeineAdenosine receptor A2btarget
CaffeineAdenosine receptor A3target
CaffeinePhosphodiesterase enzymestarget
MethylphenidateSodium-dependent dopamine transportertarget
MethylphenidateSodium-dependent noradrenaline transportertarget
MethylphenidateCarboxylesteraseenzyme
Methylphenidate5-hydroxytryptamine receptor 1Atarget
ModafinilSodium-dependent dopamine transportertarget
ModafinilAlpha-1B adrenergic receptortarget
ModafinilCytochrome P450 3A4enzyme
ModafinilCytochrome P450 2C19enzyme
ModafinilCytochrome P450 1A2enzyme
ModafinilCytochrome P450 2B6enzyme
ModafinilCytochrome P450 2C9enzyme
ModafinilCytochrome P450 3A5enzyme
ModafinilCytochrome P450 2D6enzyme
LisdexamfetamineSolute carrier family 15 member 1transporter
LisdexamfetamineTrace amine-associated receptor 1target
FencamfaminSodium-dependent dopamine transportertarget
DextroamphetamineAlpha-1B adrenergic receptortarget
DextroamphetamineSodium-dependent dopamine transportertarget
DextroamphetamineSodium-dependent noradrenaline transportertarget
DextroamphetamineSynaptic vesicular amine transportertarget
DextroamphetamineTrace amine-associated receptor 1target
DextroamphetamineCytochrome P450 2D6enzyme
DextroamphetaminePrimary amine oxidaseenzyme
DextroamphetamineSodium-dependent dopamine transportertransporter
DextroamphetamineAlpha adrenergic receptortarget
MetamfetamineCytochrome P450 2D6enzyme
MetamfetamineSolute carrier family 22 member 3transporter
MetamfetamineSolute carrier family 22 member 5transporter
MetamfetamineSodium-dependent dopamine transportertarget
MetamfetamineSynaptic vesicular amine transportertarget
MetamfetamineTrace amine-associated receptor 1target
MetamfetamineSodium-dependent serotonin transportertarget
MetamfetamineSodium-dependent noradrenaline transportertarget
MetamfetamineChromaffin granule amine transportertarget
MetamfetamineAmine oxidase [flavin-containing] Atarget
MetamfetamineAmine oxidase [flavin-containing] Btarget
MetamfetamineAlpha-2A adrenergic receptortarget
MetamfetamineAlpha-2B adrenergic receptortarget
MetamfetamineAlpha-2C adrenergic receptortarget
Aniracetam5-hydroxytryptamine receptor 2Atarget
AniracetamDopamine D2 receptortarget
AniracetamGlutamate receptor 2target
AniracetamGlutamate receptor 3target
ArmodafinilCytochrome P450 2C19enzyme
ArmodafinilCytochrome P450 3A4enzyme
ArmodafinilCytochrome P450 1A2enzyme
ArmodafinilCytochrome P450 2B6enzyme
ArmodafinilCytochrome P450 3A5enzyme
ArmodafinilCytochrome P450 2C9enzyme
ArmodafinilSodium-dependent dopamine transportertarget
PropentofyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
PropentofyllineCytochrome P450 1A2enzyme
DexmethylphenidateSodium-dependent dopamine transportertarget
DexmethylphenidateSodium-dependent noradrenaline transportertarget
DexmethylphenidateSodium-dependent serotonin transportertarget
DexmethylphenidateCarboxylesteraseenzyme
AcetylcarnitineSolute carrier family 22 member 5transporter
AcetylcarnitineSolute carrier family 22 member 21transporter
PipradrolD(1) dopamine receptortarget
VinpocetineCytochrome P450 3A4enzyme
FenethyllineCytochrome P450 1A2enzyme
CiticolineLicC proteintarget
AtomoxetineSodium-dependent noradrenaline transportertarget
AtomoxetineCytochrome P450 2D6enzyme
AtomoxetineSodium-dependent serotonin transportertarget
AtomoxetineCytochrome P450 2C19enzyme
AtomoxetineNMDA receptortarget
AtomoxetineSerum albumincarrier
Atomoxetinealpha1-acid glycoproteincarrier
AtomoxetineHigh affinity immunoglobulin gamma Fc receptor Icarrier
AtomoxetineG protein-activated inward rectifier potassium channel 1target
AtomoxetineKappa-type opioid receptortarget
SolriamfetolSolute carrier family 22 member 2transporter
SolriamfetolSolute carrier family 22 member 4transporter
SolriamfetolSolute carrier family 22 member 5transporter
SolriamfetolSodium-dependent dopamine transportertarget
SolriamfetolSodium-dependent noradrenaline transportertarget
SerdexmethylphenidateSodium-dependent dopamine transportertarget
SerdexmethylphenidateSodium-dependent noradrenaline transportertarget
Serdexmethylphenidate5-hydroxytryptamine receptor 1Atarget
SerdexmethylphenidateCarboxylesteraseenzyme