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Identification
NameIbuprofen
Accession NumberDB01050  (APRD00372)
TypeSmall Molecule
GroupsApproved
Description

Ibuprofen, a propionic acid derivative, is a prototypical nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.

Structure
Thumb
Synonyms
SynonymLanguageCode
(+-)-2-(P-Isobutylphenyl)propionic acidNot AvailableNot Available
(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acidNot AvailableNot Available
(+-)-IbuprofenNot AvailableNot Available
(+-)-P-Isobutylhydratropic acidNot AvailableNot Available
(4-Isobutylphenyl)-alpha-methylacetic acidNot AvailableNot Available
(RS)-ibuprofenNot AvailableNot Available
2-(4-Isobutylphenyl)propanoic acidNot AvailableNot Available
4-Isobutylhydratropic acidNot AvailableNot Available
AdranNot AvailableNot Available
AdvilNot AvailableNot Available
alpha-(4-Isobutylphenyl)propionic acidNot AvailableNot Available
alpha-(P-Isobutylphenyl)propionic acidNot AvailableNot Available
AmibufenNot AvailableNot Available
AncoNot AvailableNot Available
AnflagenNot AvailableNot Available
ApsifenNot AvailableNot Available
BlutonNot AvailableNot Available
BrufenNot AvailableNot Available
BrufortNot AvailableNot Available
BuburoneNot AvailableNot Available
ButyleninNot AvailableNot Available
DolginNot AvailableNot Available
DolgiridNot AvailableNot Available
DolgitNot AvailableNot Available
Dolo-dolgitNot AvailableNot Available
EbufacNot AvailableNot Available
EpobronNot AvailableNot Available
FemadonNot AvailableNot Available
HaltranNot AvailableNot Available
Ibu-attritinNot AvailableNot Available
IbumetinNot AvailableNot Available
IbuprocinNot AvailableNot Available
IbuprofenNot AvailableNot Available
IbuprophenNot AvailableNot Available
IbutidNot AvailableNot Available
InabrinNot AvailableNot Available
InovenNot AvailableNot Available
LamidonNot AvailableNot Available
LebrufenNot AvailableNot Available
LiptanNot AvailableNot Available
MediprenNot AvailableNot Available
MotrinNot AvailableNot Available
MynosedinNot AvailableNot Available
NobfenNot AvailableNot Available
NobgenNot AvailableNot Available
NuprinNot AvailableNot Available
NurofenNot AvailableNot Available
P-Isobutylhydratropic AcidNot AvailableNot Available
Para-Isobutylhydratropic AcidNot AvailableNot Available
PediaprofenNot AvailableNot Available
RoideninNot AvailableNot Available
RufenNot AvailableNot Available
SeclodinNot AvailableNot Available
SusprenNot AvailableNot Available
TabalonNot AvailableNot Available
TrendarNot AvailableNot Available
UremNot AvailableNot Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Neoprofensolution10 mg/mLintravenousRECORDATI RARE DISEASES, INC.2006-04-13Not AvailableUs
Caldolorinjection100 mg/mLintravenousCumberland Pharmaceuticals Inc.2009-06-11Not AvailableUs
Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Ibuprofensuspension100 mg/5mLoralPharmaceutical Associates, Inc.2004-09-23Not AvailableUs
Ibuprofentablet, film coated800 mgoralKAISER FOUNDATION HOSPITALS2009-11-30Not AvailableUs
Ibutablet600 mgoralKAISER FOUNDATION HOSPITALS2012-05-09Not AvailableUs
Ibutablet800 mgoralKAISER FOUNDATION HOSPITALS2012-06-05Not AvailableUs
Ibuprofensuspension100 mg/5mLoralActavis Mid Atlantic LLC2002-09-27Not AvailableUs
Ibuprofentablet400 mgoralQualitest Pharmaceuticals2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralQualitest Pharmaceuticals2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralQualitest Pharmaceuticals2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralMajor Pharmaceuticals2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralMajor Pharmaceuticals2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralMajor Pharmaceuticals2009-11-23Not AvailableUs
Ibuprofentablet, film coated400 mgoralMajor Pharmaceuticals2009-06-10Not AvailableUs
Ibuprofentablet, film coated600 mgoralMajor Pharmaceuticals2009-06-10Not AvailableUs
Ibuprofentablet, film coated800 mgoralMajor Pharmaceuticals2009-06-10Not AvailableUs
Ibuprofentablet600 mgoralBlenheim Pharmacal, Inc.2010-09-08Not AvailableUs
Ibuprofentablet400 mgoralBlenheim Pharmacal, Inc.2010-03-10Not AvailableUs
Ibuprofentablet600 mgoralBlenheim Pharmacal, Inc.2010-04-28Not AvailableUs
Ibuprofentablet800 mgoralBlenheim Pharmacal, Inc.2010-05-17Not AvailableUs
Perrigo Ibuprofentablet600 mgoralPerrigo Pharmaceuticals Company2006-03-16Not AvailableUs
Ibuprofentablet800 mgoralPerrigo Pharmaceuticals Company2006-05-08Not AvailableUs
Ibuprofentablet400 mgoralHHS/Program Support Center/Supply Service Center2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralApotheca, Inc.1991-02-11Not AvailableUs
Ibuprofentablet600 mgoralApotheca, Inc.1996-12-23Not AvailableUs
Ibuprofentablet200 mgoralApotheca, Inc2014-02-14Not AvailableUs
Ibuprofentablet800 mgoralApotheca, Inc.2009-02-09Not AvailableUs
Ibuprofentablet400 mgoralSTAT Rx USA LLC2008-11-20Not AvailableUs
Ibuprofentablet600 mgoralSTAT Rx USA LLC2008-11-20Not AvailableUs
Ibuprofentablet800 mgoralSTAT Rx USA LLC2008-11-20Not AvailableUs
Ibuprofensuspension100 mg/5mLoralSTAT Rx USA LLC2004-12-08Not AvailableUs
Ibuprofentablet, film coated400 mgoralRebel Distributors Corp2009-06-10Not AvailableUs
Ibuprofentablet, film coated600 mgoralRebel Distributors Corp2009-06-10Not AvailableUs
Ibuprofentablet, film coated800 mgoralRebel Distributors Corp2009-06-10Not AvailableUs
Ibuprofensuspension100 mg/5mLoralRebel Distributors Corp2004-09-23Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2013-04-03Not AvailableUs
Ibuprofentablet400 mgoralMARKSANS PHARMA LIMITED2011-02-28Not AvailableUs
Ibuprofentablet600 mgoralMARKSANS PHARMA LIMITED2011-02-28Not AvailableUs
Ibuprofentablet800 mgoralMARKSANS PHARMA LIMITED2011-02-28Not AvailableUs
Ibuprofentablet600 mgoralAidarex Pharmaceuticals LLC2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralAidarex Pharmaceuticals LLC2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralAidarex Pharmaceuticals LLC2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralRx Change Co.2014-11-09Not AvailableUs
Ibuprofentablet800 mgoralRx Change Co.2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2009-11-23Not AvailableUs
Ibutablet600 mgoralLake Erie Medical DBA Quality Care Products LLC2008-11-20Not AvailableUs
Ibuprofentablet600 mgoralRebel Distributors Corp2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralRebel Distributors Corp2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralRebel Distributors Corp2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralAv Kare, Inc.2013-01-10Not AvailableUs
Ibuprofentablet600 mgoralAv Kare, Inc.2013-01-10Not AvailableUs
Ibuprofentablet800 mgoralAv Kare, Inc.2013-01-10Not AvailableUs
Ibuprofentablet, film coated600 mgoralSTAT Rx USA LLC2009-11-23Not AvailableUs
Ibuprofentablet, film coated800 mgoralSTAT Rx USA LLC2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralPd Rx Pharmaceuticals, Inc.2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralPd Rx Pharmaceuticals, Inc.2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralPd Rx Pharmaceuticals, Inc.2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralAphena Pharma Solutions Tennessee, Inc.2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralAphena Pharma Solutions Tennessee, Inc.2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralAphena Pharma Solutions Tennessee, Inc.2009-11-23Not AvailableUs
Ibuprofensuspension100 mg/5mLoralPerrigo New York Inc2004-12-08Not AvailableUs
Ibuprofentablet800 mgoralMedsource Pharmaceuticals2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2012-08-30Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2010-11-23Not AvailableUs
Ibuprofentablet200 mgoralREMEDYREPACK INC.2010-12-08Not AvailableUs
Ibuprofentablet400 mgoralREMEDYREPACK INC.2011-04-18Not AvailableUs
Ibuprofentablet400 mgoralREMEDYREPACK INC.2011-04-18Not AvailableUs
Ibuprofentablet400 mgoralREMEDYREPACK INC.2011-04-18Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2011-04-21Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2011-04-21Not AvailableUs
Ibuprofentablet400 mgoralREMEDYREPACK INC.2011-04-26Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2011-07-08Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2013-07-25Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2013-07-25Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2011-07-12Not AvailableUs
Ibuprofentablet400 mgoralREMEDYREPACK INC.2011-08-11Not AvailableUs
Ibuprofentablet400 mgoralREMEDYREPACK INC.2012-08-29Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2013-07-25Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2011-03-11Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2011-11-04Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2011-05-10Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2013-12-11Not AvailableUs
Ibuprofentablet600 mgoralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2011-11-21Not AvailableUs
Ibutablet800 mgoralLake Erie Medical DBA Quality Care Products LLC2010-10-19Not AvailableUs
Ibuprofentablet400 mgoralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2011-11-21Not AvailableUs
Ibutablet400 mgoralUnit Dose Services2008-11-20Not AvailableUs
Ibutablet600 mgoralUnit Dose Services2008-11-20Not AvailableUs
Ibuprofentablet800 mgoralUnit Dose Services2009-11-23Not AvailableUs
Ibuprofentablet, film coated800 mgoralMed Health Pharma, LLC2012-10-01Not AvailableUs
Ibuprofentablet, film coated600 mgoralNorthwind Pharmaceuticals, LLC2014-10-28Not AvailableUs
Ibuprofentablet, film coated400 mg/301oralNorthwind Pharmaceuticals2014-05-20Not AvailableUs
Ibuprofentablet600 mgoralNorthwind Pharmaceuticals, LLC2014-08-14Not AvailableUs
Ibuprofentablet800 mgoralNorthwind Pharmaceuticals2014-06-01Not AvailableUs
Ibuprofentablet400 mgoralREMEDYREPACK INC.2013-05-01Not AvailableUs
Ibuprofentablet400 mgoralREMEDYREPACK INC.2013-02-11Not AvailableUs
Ibuprofentablet400 mgoralREMEDYREPACK INC.2013-02-11Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2013-05-13Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2013-05-13Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2013-10-08Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2013-05-30Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2013-07-25Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2013-08-21Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2013-07-16Not AvailableUs
Ibuprofentablet800 mgoralREMEDYREPACK INC.2013-07-25Not AvailableUs
Ibuprofentablet, film coated600 mgoralREMEDYREPACK INC.2013-07-16Not AvailableUs
Ibuprofentablet, film coated600 mgoralREMEDYREPACK INC.2013-07-16Not AvailableUs
Ibuprofentablet, film coated600 mgoralREMEDYREPACK INC.2013-08-28Not AvailableUs
Ibuprofentablet, film coated600 mgoralREMEDYREPACK INC.2013-07-31Not AvailableUs
Ibuprofentablet400 mgoralREMEDYREPACK INC.2013-09-19Not AvailableUs
Ibuprofentablet400 mgoralREMEDYREPACK INC.2013-11-01Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2013-12-31Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2013-11-20Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2013-11-20Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2013-11-20Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2013-11-20Not AvailableUs
Ibuprofentablet600 mgoralREMEDYREPACK INC.2014-06-05Not AvailableUs
Ibuprofentablet400 mgoralREMEDYREPACK INC.2014-06-05Not AvailableUs
Ibuprofentablet, film coated400 mgoralPolygen Pharmaceuticals LLC2011-11-28Not AvailableUs
Ibuprofentablet, film coated600 mgoralPolygen Pharmaceuticals LLC2011-11-28Not AvailableUs
Ibuprofentablet, film coated800 mgoralPolygen Pharmaceuticals LLC2011-11-28Not AvailableUs
Ibuprofentablet400 mgoralH.J. Harkins Company, Inc.2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralH.J. Harkins Company, Inc.2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralH.J. Harkins Company, Inc.2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralAmneal Pharmaceuticals of New York, LLC2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralAmneal Pharmaceuticals of New York, LLC2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralAmneal Pharmaceuticals of New York, LLC2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs
Ibuprofentablet, film coated400 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs
Ibuprofentablet, film coated800 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs
Ibuprofentablet600 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs
Ibuprofentablet, film coated600 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs
Ibuprofentablet400 mgoralA S Medication Solutions Llc2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralA S Medication Solutions Llc2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralA S Medication Solutions Llc2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralA S Medication Solutions Llc2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralA S Medication Solutions Llc2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralA S Medication Solutions Llc2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralPhysicians Total Care, Inc.1997-02-20Not AvailableUs
Ibuprofentablet600 mgoralPhysicians Total Care, Inc.1997-05-08Not AvailableUs
Ibuprofentablet800 mgoralPhysicians Total Care, Inc.1994-12-20Not AvailableUs
Ibuprofentablet600 mgoralDispensing Solutions, Inc.2009-11-23Not AvailableUs
Ibutablet400 mgoralDr. Reddy's Laboratories Limited2008-11-20Not AvailableUs
Ibutablet600 mgoralDr. Reddy's Laboratories Limited2008-11-20Not AvailableUs
Ibutablet800 mgoralDr. Reddy's Laboratories Limited2008-11-20Not AvailableUs
Ibuprofentablet, film coated600 mgoralCardinal Health2009-06-10Not AvailableUs
Ibuprofentablet600 mgoralCardinal Health2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralCardinal Health2009-11-23Not AvailableUs
Ibuprofentablet, film coated800 mgoralCardinal Health2009-06-10Not AvailableUs
Ibuprofentablet, film coated400 mgoralCardinal Health2009-06-10Not AvailableUs
Ibutablet400 mgoralCardinal Health2009-07-20Not AvailableUs
Ibuprofentablet600 mgoralCardinal Health2011-03-23Not AvailableUs
Ibuprofentablet400 mgoralCardinal Health2012-02-22Not AvailableUs
Ibuprofensuspension100 mg/5mLoralCardinal Health2012-08-16Not AvailableUs
Ibuprofentablet600 mgoralCardinal Health2013-10-14Not AvailableUs
Ibutablet800 mgoralCardinal Health2009-06-17Not AvailableUs
Ibuprofentablet400 mgoralCardinal Health2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralPd Rx Pharmaceuticals, Inc.2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralPd Rx Pharmaceuticals, Inc.2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralPd Rx Pharmaceuticals, Inc.2009-11-23Not AvailableUs
Ibuprofen Immediate releasetablet800 mgoralShasun Pharmaceuticals Limited2009-02-05Not AvailableUs
Ibuprofen Immediate releasetablet600 mgoralShasun Pharmaceuticals Limited2009-02-05Not AvailableUs
Ibuprofen Immediate releasetablet400 mgoralShasun Pharmaceuticals Limited2009-02-05Not AvailableUs
Ibuprofentablet400 mgoralClinical Solutions Wholesale2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralClinical Solutions Wholesale2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralClinical Solutions Wholesale2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralGolden State Medical Supply, Inc.2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralGolden State Medical Supply, Inc.2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralGolden State Medical Supply, Inc.2009-11-23Not AvailableUs
Ibutablet400 mgoralGolden State Medical Supply, Inc.2014-04-22Not AvailableUs
Ibutablet600 mgoralGolden State Medical Supply, Inc.2014-04-22Not AvailableUs
Ibutablet800 mgoralGolden State Medical Supply, Inc.2014-04-22Not AvailableUs
Ibuprofentablet400 mgoralSt Marys Medical Park Pharmacy2013-07-11Not AvailableUs
Ibuprofentablet, film coated200 mgoralREMEDYREPACK INC.2015-02-13Not AvailableUs
Ibuprofentablet, film coated400 mgoralDIRECT RX2014-01-01Not AvailableUs
Ibuprofentablet, film coated600 mgoralDIRECT RX2014-01-01Not AvailableUs
Ibuprofentablet, film coated800 mgoralDIRECT RX2014-01-01Not AvailableUs
Ibuprofentablet400 mgoralAmerican Health Packaging2011-03-23Not AvailableUs
Ibuprofentablet600 mgoralAmerican Health Packaging2011-03-23Not AvailableUs
Ibuprofentablet800 mgoralAmerican Health Packaging2011-03-24Not AvailableUs
Ibuprofentablet800 mgoralProficient Rx LP2009-11-23Not AvailableUs
Ibuprofentablet, film coated200 mgoralbryant ranch prepack2004-01-01Not AvailableUs
Ibutablet400 mgoralbryant ranch prepack2008-11-20Not AvailableUs
Ibuprofentablet600 mgoralbryant ranch prepack2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralbryant ranch prepack2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralbryant ranch prepack2009-11-23Not AvailableUs
Ibutablet400 mgoralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2009-07-20Not AvailableUs
Ibutablet600 mgoralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2009-07-09Not AvailableUs
Ibutablet800 mgoralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2009-06-17Not AvailableUs
Ibuprofentablet400 mgoralMc Kesson Packaging Serivces A Business Unit Of Mc Kesson Corporation2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralMc Kesson Packaging Serivces A Business Unit Of Mc Kesson Corporation2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralMc Kesson Packaging Serivces A Business Unit Of Mc Kesson Corporation2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralAltura Pharmaceuticals, Inc.2010-01-01Not AvailableUs
Ibuprofentablet800 mgoralAltura Pharmaceuticals, Inc.2010-01-01Not AvailableUs
Ibuprofentablet600 mgoralAltura Pharmaceuticals, Inc.2010-01-01Not AvailableUs
Ibuprofentablet600 mgoralTYA Pharmaceuticals2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralRising Pharmaceuticals, Inc.2011-07-01Not AvailableUs
Ibuprofentablet600 mgoralRising Pharmaceuticals, Inc.2011-07-01Not AvailableUs
Ibuprofentablet800 mgoralRising Pharmaceuticals, Inc.2011-07-01Not AvailableUs
Ibuprofentablet, film coated400 mgoralAmneal Pharmaceuticals of New York, LLC2014-04-012015-03-31Us
Ibuprofentablet, film coated600 mgoralAmneal Pharmaceuticals of New York, LLC2014-04-012015-03-31Us
Ibuprofentablet, film coated800 mgoralAmneal Pharmaceuticals of New York, LLC2014-04-012015-03-31Us
Ibuprofentablet400 mgoralMed Vantx, Inc.2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralMed Vantx, Inc.2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralMed Vantx, Inc.2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralDispensing Solutions, Inc.2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralDispensing Solutions, Inc.2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralDispensing Solutions, Inc.2009-11-23Not AvailableUs
Ibuprofensuspension100 mg/5mLoralVista Pharm, Inc.2012-08-16Not AvailableUs
Ibuprofentablet600 mgoralContract Pharmacy Services Pa2010-04-14Not AvailableUs
Ibuprofentablet400 mgoralContract Pharmacy Services Pa2010-04-12Not AvailableUs
Ibuprofentablet400 mgoralContract Pharmacy Services Pa2009-09-22Not AvailableUs
Ibuprofentablet600 mgoralContract Pharmacy Services Pa2009-09-22Not AvailableUs
Ibuprofentablet800 1oralContract Pharmacy Services Pa2009-10-01Not AvailableUs
Ibuprofentablet800 1oralContract Pharmacy Services Pa2010-04-14Not AvailableUs
Ibuprofentablet800 mgoralRed Pharm Drug Inc.2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralRed Pharm Drug Inc.2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralRed Pharm Drug Inc.2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralAscend Laboratories, LLC2009-02-06Not AvailableUs
Ibuprofentablet600 mgoralAscend Laboratories, LLC2009-02-06Not AvailableUs
Ibuprofentablet800 mgoralAscend Laboratories, LLC2009-02-06Not AvailableUs
Ibuprofentablet400 mgoralAscend Laboratories, LLC2012-02-22Not AvailableUs
Ibuprofentablet600 mgoralAscend Laboratories, LLC2012-02-22Not AvailableUs
Ibuprofentablet800 mgoralAscend Laboratories, LLC2012-02-22Not AvailableUs
Ibuprofentablet400 mgoralAmerican Health Packaging2013-10-14Not AvailableUs
Ibuprofentablet600 mgoralAmerican Health Packaging2013-10-14Not AvailableUs
Ibuprofentablet800 mgoralAmerican Health Packaging2013-10-14Not AvailableUs
Ibuprofentablet600 mgoralKeltman Pharmaceuticals Inc.2007-08-24Not AvailableUs
Ibuprofentablet800 mgoralKeltman Pharmaceuticals Inc.2007-08-24Not AvailableUs
Ibuprofentablet400 mgoralLegacy Pharmaceutical Packaging2008-11-202015-08-31Us
Ibuprofentablet600 mgoralLegacy Pharmaceutical Packaging2008-11-202015-08-31Us
Ibuprofentablet800 mgoralLegacy Pharmaceutical Packaging2008-11-202015-09-30Us
Ibuprofentablet400 mgoralLegacy Pharmaceutical Packaging2011-02-28Not AvailableUs
Ibuprofentablet600 mgoralLegacy Pharmaceutical Packaging2011-02-28Not AvailableUs
Ibuprofentablet800 mgoralLegacy Pharmaceutical Packaging2011-02-28Not AvailableUs
Ibuprofensuspension100 mg/5mLoralPreferred Pharmaceuticals, Inc2011-07-05Not AvailableUs
Ibuprofentablet400 mgoralPreferred Pharmaceuticals, Inc.2008-11-20Not AvailableUs
Ibuprofentablet600 mgoralPreferred Pharmaceuticals, Inc.2008-11-20Not AvailableUs
Ibuprofentablet800 mgoralPreferred Pharmaceuticals, Inc.2008-11-20Not AvailableUs
Ibuprofentablet400 mgoralPreferred Pharmaceuticals, Inc.2009-11-23Not AvailableUs
Ibuprofentablet600 mgoralPreferred Pharmaceuticals, Inc.2009-11-23Not AvailableUs
Ibuprofentablet800 mgoralPreferred Pharmaceuticals, Inc.2009-11-23Not AvailableUs
Ibuprofentablet400 mgoralPreferred Pharmaceuticals, Inc.2012-09-28Not AvailableUs
Ibuprofentablet600 mgoralPreferred Pharmaceuticals, Inc.2012-09-28Not AvailableUs
Ibuprofentablet800 mgoralPreferred Pharmaceuticals, Inc.2012-09-28Not AvailableUs
Ibuprofentablet, coated400 mgoralBiomes Pharmaceuticals LLC2009-05-02Not AvailableUs
Ibuprofentablet, coated600 mgoralBiomes Pharmaceuticals LLC2009-05-02Not AvailableUs
Ibuprofentablet, coated800 mgoralBiomes Pharmaceuticals LLC2009-05-02Not AvailableUs
Ibuprofentablet, film coated400 mgoralAmneal Pharmaceuticals of New York, LLC2014-04-01Not AvailableUs
Ibuprofentablet, film coated600 mgoralAmneal Pharmaceuticals of New York, LLC2014-04-01Not AvailableUs
Ibuprofentablet, film coated800 mgoralAmneal Pharmaceuticals of New York, LLC2014-04-01Not AvailableUs
Ibuprofentablet800 mgoralLife Line Home Care Services, Inc.2012-02-13Not AvailableUs
Ibuprofentablet400 mgoralMc Kesson Contract Packaging2012-01-05Not AvailableUs
Ibuprofentablet600 mgoralMc Kesson Contract Packaging2011-12-22Not AvailableUs
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Good Sense Ibuprofen infantssuspension50 mg/1.25mLoralL Perrigo Company2000-02-08Not AvailableUs
Good Sense Ibuprofentablet, coated200 mgoralL Perrigo Company2006-03-10Not AvailableUs
Good Sense Ibuprofencapsule, liquid filled200 mgoralL Perrigo Company2010-01-28Not AvailableUs
Good Sense Ibuprofen childrenssuspension100 mg/5mLoralL. Perrigo Company2002-05-04Not AvailableUs
Good Sense Ibuprofentablet, chewable100 mgoralL Perrigo Company2004-11-09Not AvailableUs
Good Sense Ibuprofentablet, film coated200 mgoralL Perrigo Company2006-04-27Not AvailableUs
Good Sense Ibuprofentablet, film coated200 mgoralL Perrigo Company1989-09-15Not AvailableUs
Good Sense Ibuprofentablet, coated200 mgoralL Perrigo Company1991-02-15Not AvailableUs
Good Sense Ibuprofen Childrenssuspension100 mg/5mLoralL. Perrigo Company2002-04-09Not AvailableUs
Good Sense Ibuprofenliquid100 mg/5mLoralL Perrigo Company1994-05-09Not AvailableUs
Good Sense Ibuprofen childrenssuspension100 mg/5mLoralL. Perrigo Company1999-01-07Not AvailableUs
Good Sense Childrens Ibuprofen Oral Suspensionsuspension100 mg/5mLoralL Perrigo Company2002-04-09Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralPharmaceutical Associates, Inc.2014-12-01Not AvailableUs
Midolcapsule, liquid filled200 mgoralBayer Health Care Llc Consumer Care2009-05-18Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralWalgreen Company2011-05-09Not AvailableUs
Ibuprofen Infantssuspension50 mg/1.25mLoralWalgreen Company2001-04-13Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralWalgreen Company2002-03-04Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralWalgreens2013-09-30Not AvailableUs
Ibuprofensuspension/ drops50 mg/1.25mLoralWalgreen Company2005-05-13Not AvailableUs
Ibuprofentablet200 mgoralWALGREEN CO.1988-05-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralWALGREEN CO.1988-05-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralWALGREEN CO.2002-03-30Not AvailableUs
Ibuprofen 200capsule, coated200 mgoralWALGREEN CO.2002-04-08Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralWalgreens2014-08-31Not AvailableUs
Dye Free Ibuprofentablet200 mgoralWALGREEN CO.2004-03-11Not AvailableUs
Ibuprofentablet, chewable100 mgoralWalgreen Company2013-12-09Not AvailableUs
Ibuprofentablet, chewable100 mgoralWalgreen Company2009-05-05Not AvailableUs
Ibuprofen Junior Strengthtablet, chewable100 mgoralWalgreen Company2012-12-18Not AvailableUs
Ibuprofentablet, film coated200 mgoralWalgreen Company2009-01-21Not AvailableUs
Ibuprofen Childrenssuspension100 mg/5mLoralWalgreen Company2002-03-25Not AvailableUs
Ibuprofenliquid100 mg/5mLoralWalgreen Company2008-07-24Not AvailableUs
Childrens Ibuprofen 100 Dye Freesuspension100 mg/5mLoralWalgreen Company2014-02-24Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralWalgreen Company1999-03-11Not AvailableUs
Infants Dye-free Ibuprofensuspension50 mg/1.25mLoralWalgreen Company2010-05-24Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralWalgreen Company2010-05-24Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralWalgreen Company2010-05-24Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralWalgreen Company2010-05-24Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralWalgreen Company2010-05-24Not AvailableUs
Henry Schein Ibuprofentablet, film coated200 mgoralHenry Schein Inc.2008-12-30Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralActavis Mid Atlantic LLC2006-06-01Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralActavis Mid Atlantic LLC2006-06-01Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralActavis Mid Atlantic LLC2006-06-01Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralActavis Mid Atlantic LLC2006-06-01Not AvailableUs
Cedaprintablet200 mgoralNorth Safety Products LLC2012-03-07Not AvailableUs
Ibuprofentablet, coated200 mgoralRugby Laboratories Inc2011-03-01Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralRugby Laboratories, Inc.2012-03-26Not AvailableUs
Adviltablet, coated256 mgoralPfizer Consumer Healthcare2013-07-08Not AvailableUs
Adviltablet, coated256 mgoralPfizer Consumer Healthcare2013-07-08Not AvailableUs
Adviltablet, coated200 mgoralPfizer Consumer Healthcare1984-05-18Not AvailableUs
Adviltablet, coated200 mgoralPfizer Consumer Healthcare1984-05-18Not AvailableUs
Adviltablet, coated200 mgoralPfizer Consumer Healthcare1984-05-18Not AvailableUs
Adviltablet, coated200 mgoralPfizer Consumer Healthcare1984-05-18Not AvailableUs
Adviltablet, coated200 mgoralPfizer Consumer Healthcare1984-05-18Not AvailableUs
Adviltablet, coated200 mgoralPfizer Consumer Healthcare1984-05-18Not AvailableUs
Adviltablet, coated200 mgoralPfizer Consumer Healthcare1984-05-18Not AvailableUs
Advil Migrainecapsule, liquid filled200 mgoralPfizer Consumer Healthcare2000-03-16Not AvailableUs
Advilcapsule, liquid filled200 mgoralPfizer Consumer Healthcare1995-04-10Not AvailableUs
Childrens Advilsuspension100 mg/5mLoralPfizer Consumer Healthcare1996-06-27Not AvailableUs
Childrens Advilsuspension100 mg/5mLoralPfizer Consumer Healthcare1996-06-27Not AvailableUs
Childrens Advilsuspension100 mg/5mLoralPfizer Consumer Healthcare1996-06-27Not AvailableUs
Junior Strength Adviltablet, coated100 mgoralPfizer Consumer Healthcare2011-06-21Not AvailableUs
Junior Strength Adviltablet, chewable100 mgoralPfizer Consumer Healthcare2011-06-01Not AvailableUs
Infants Advilsuspension/ drops50 mg/1.25mLoralPfizer Consumer Healthcare1998-01-30Not AvailableUs
Childrens Advilsuspension100 mg/5mLoralPfizer Consumer Healthcare2012-11-01Not AvailableUs
Childrens Advilsuspension100 mg/5mLoralPfizer Consumer Healthcare2014-06-01Not AvailableUs
Childrens Advilsuspension100 mg/5mLoralPfizer Consumer Healthcare2010-06-28Not AvailableUs
Ibuprofentablet200 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2009-12-16Not AvailableUs
Ibuprofensuspension100 mg/5mLoralMajor Pharmaceuticals1999-02-07Not AvailableUs
Ibuprofentablet, coated200 mgoralMajor Pharmaceuticals1998-06-172015-05-31Us
Ibuprofensuspension50 mg/1.25mLoralMajor Pharmaceuticals2000-01-08Not AvailableUs
Major Childrens Ibuprofensuspension100 mg/5mLoralMajor Pharmaceuticals2000-02-01Not AvailableUs
Ibuprofen Childrenssuspension100 mg/5mLoralMajor Pharmaceuticals2002-04-03Not AvailableUs
Ibuprofentablet, coated200 mgoralMajor Pharmaceuticals1994-08-16Not AvailableUs
Ibuprofentablet, film coated200 mgoralMajor Pharmaceuticals2007-11-06Not AvailableUs
Ibuprofentablet, film coated200 mgoralMajor Pharmaceuticals1988-05-24Not AvailableUs
Physicianscare Ibuprofentablet200 mgoralAcme United Corporation2011-10-07Not AvailableUs
Fulton Street Market Ibuprofentablet, film coated200 mgoralAccess Business Group LLC1991-01-15Not AvailableUs
Formu Care Ibuprofentablet200 mgoralAccess Business Group LLC1991-01-15Not AvailableUs
Formu Care Ibuprofen childrenssuspension100 mg/5mLoralAccess Business Group LLC1999-01-19Not AvailableUs
7 Select Ibuprofentablet, film coated200 mgoral7 Eleven2014-08-07Not AvailableUs
7 Select Ibuprofentablet, coated200 mgoral7 Eleven2014-05-13Not AvailableUs
7 Select Childrens Ibuprofensuspension100 mg/5mLoral7 Eleven2014-08-05Not AvailableUs
Ibuprofentablet200 mgoralContract Pharmacal Corporation2014-12-01Not AvailableUs
Ibuprofentablet200 mgoralContract Pharmacal Corporation2014-01-15Not AvailableUs
Ibuprofentablet200 mgoralContract Pharmacal Corporation2014-12-01Not AvailableUs
Ibuprofentablet, coated200 mgoralWeeks & Leo Co., Inc.2013-05-17Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralTarget Corporation2010-08-01Not AvailableUs
Ibuprofentablet200 mgoralTarget Corporation2011-09-14Not AvailableUs
Ibuprofentablet, coated200 mgoralTarget Corporation2013-11-30Not AvailableUs
Ibuprofentablet, coated200 mgoralTarget Corporation2014-03-28Not AvailableUs
Ibuprofentablet, chewable100 mgoralRite Aid Corporation2004-05-06Not AvailableUs
Ibuprofensuspension50 mg/1.25mLoralRite Aid Corporation2004-05-06Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralRite Aid Corporation2002-05-10Not AvailableUs
Ibuprofensuspension/ drops50 mg/1.25mLoralRite Aid Corporation2005-06-03Not AvailableUs
Ibuprofentablet200 mgoralRite Aid1988-05-24Not AvailableUs
Pain Relief Ibuprofentablet200 mgoralRite Aid1988-05-24Not AvailableUs
Pain Relief Ibuprofentablet, film coated200 mgoralRite Aid2002-03-30Not AvailableUs
Ibuprofentablet, coated200 mgoralRite Aid2002-04-08Not AvailableUs
Ibuprofentablet, chewable100 mgoralRite Aid Corporation2010-06-25Not AvailableUs
Ibuprofensuspension100 mg/5mLoralRite Aid Corporation2002-05-10Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralRite Aid Corporation1999-01-08Not AvailableUs
Infants Ibuprofenliquid50 mg/1.25mLoralRite Aid2010-05-17Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralRite Aid2008-03-20Not AvailableUs
Ibuprofentablet200 mgoralApotheca Inc.2009-09-16Not AvailableUs
Ibuprofentablet, film coated200 mgoralStephen L. La France Pharmacy, Inc.1988-05-24Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralSelect Brand Dist.2010-03-13Not AvailableUs
Ibuprofentablet, film coated200 mgoralStephen L. La France Pharmacy, Inc.1988-05-24Not AvailableUs
Infants Ibuprofenliquid50 mg/1.25mLoralStephen L. La France Pharmacy, Inc.2009-10-02Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralStephen L. La France Pharmacy, Inc.2008-02-13Not AvailableUs
Ibuprofentablet, film coated200 mgoralStephen L. La France Pharmacy, Inc.2002-03-30Not AvailableUs
Ibuprofentablet, film coated200 mgoralStephen L. La France Pharmacy, Inc.2002-04-08Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralStephen L. La France Pharmacy, Inc.2006-05-25Not AvailableUs
Ibuprofentablet, film coated200 mgoralPharbest Pharmaceuticals, Inc.2011-01-18Not AvailableUs
Ibuprofensuspension100 mg/5mLoralAtlantic Biologicals Corps1999-02-07Not AvailableUs
Ibuprofensuspension/ drops50 mg/1.25mLoralSafeway2005-07-11Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralSafeway, Inc.2010-07-06Not AvailableUs
Ibuprofentablet200 mgoralSafeway1988-05-24Not AvailableUs
Ibuprofencapsule, coated200 mgoralSafeway2002-04-08Not AvailableUs
Ibuprofentablet, film coated200 mgoralSafeway2012-08-09Not AvailableUs
Ibuprofentablet, film coated200 mgoralSafeway1997-08-14Not AvailableUs
Ibuprofentablet, coated200 mgoralSafeway1997-07-30Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralSafeway2002-05-02Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralSafeway1999-01-18Not AvailableUs
Ibuprofentablet200 mgoralSafeway1988-05-24Not AvailableUs
Good Neighbor Pharmacy Ibuprofen childrensliquid100 mg/5mLoralAmerisource Bergen1994-08-09Not AvailableUs
Good Neighbor Pharmacy Ibuprofentablet, film coated200 mgoralAmerisource Bergen2006-06-14Not AvailableUs
Good Neighbor Pharmacy Ibuprofentablet, coated200 mgoralAmerisource Bergen2006-03-28Not AvailableUs
Good Neighbor Pharmacy Childrens Ibuprofensuspension100 mg/5mLoralAmerisource Bergen2002-05-13Not AvailableUs
Good Neighbor Pharmacy Childrens Ibuprofensuspension100 mg/5mLoralAmerisource Bergen2002-04-02Not AvailableUs
Ibuprofen Softgelscapsule, liquid filled200 mgoralAmerisource Bergen Drug Corporation (Good Neighbor Pharmacy)2010-07-08Not AvailableUs
Good Neighbor Pharmacy Ibuprofentablet, chewable100 mgoralAmerisource Bergen2004-10-12Not AvailableUs
Good Neighbor Pharmacy Ibuprofensuspension/ drops50 mg/1.25mLoralAmerisource Bergen2004-10-12Not AvailableUs
Good Neighbor Pharmacy Ibuprofentablet200 mgoralAmerisource Bergen1990-01-15Not AvailableUs
Good Neighbor Pharmacy Ibuprofensuspension100 mg/5mLoralAmerisource Bergen1999-11-22Not AvailableUs
Good Neighbor Pharmacy Ibuprofentablet, coated200 mgoralAmerisource Bergen1989-09-15Not AvailableUs
Good Neighbor Pharmacy Ibuprofensuspension100 mg/5mLoralAmerisource Bergen1999-01-28Not AvailableUs
Ibuprofentablet200 mgoralMARKSANS PHARMA LIMITED2011-07-25Not AvailableUs
Ibuprofentablet200 mgoralMARKSANS PHARMA LIMITED2012-07-04Not AvailableUs
Ibuprofentablet200 mgoralMARKSANS PHARMA LIMITED2011-07-25Not AvailableUs
Ibuprofentablet200 mgoralMARKSANS PHARMA LIMITED2012-07-04Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralMARKSANS PHARMA LIMITED2011-05-09Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralThe Kroger Co.2015-01-31Not AvailableUs
Ibuprofen infantssuspension50 mg/1.25mLoralKroger Company2002-11-20Not AvailableUs
Ibuprofentablet, coated200 mgoralKroger Company2006-03-11Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralThe Kroger Co2012-05-11Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralThe Kroger Co.2012-07-12Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralThe Kroger Co.2012-07-12Not AvailableUs
Ibuprofensuspension100 mg/5mLoralKroger Company2002-11-20Not AvailableUs
Ibuprofentablet200 mgoralThe Kroger Co.2011-02-02Not AvailableUs
Ibuprofentablet, film coated200 mgoralKroger Company1993-02-28Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralThe Kroger Co.2010-07-01Not AvailableUs
Ibuprofentablet200 mgoralThe Kroger Co.2014-02-28Not AvailableUs
Ibuprofensuspension/ drops50 mg/1.25mLoralKroger Company2010-05-15Not AvailableUs
Ibuprofentablet, chewable100 mgoralKroger Company2004-05-10Not AvailableUs
Ibuprofentablet, film coated200 mgoralKroger Company2006-04-27Not AvailableUs
Ibuprofentablet200 mgoralKroger Company1988-01-15Not AvailableUs
Ibuprofentablet, coated200 mgoralKroger Company1990-10-15Not AvailableUs
Ibuprofen Childrenssuspension100 mg/5mLoralKroger Company2002-11-20Not AvailableUs
Ibuprofensuspension100 mg/5mLoralKroger Company2011-04-25Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralKroger Company1999-01-19Not AvailableUs
Ibuprofentablet, film coated200 mgoralAidarex Pharmaceuticals LLC1994-08-16Not AvailableUs
Ibuprofentablet200 mgoralGreenbrier International, Inc.1988-05-24Not AvailableUs
Ibutabtablet200 mgoralZee Medical Inc2012-06-12Not AvailableUs
Topcare Infants Ibuprofensuspension50 mg/1.25mLoralTopco Associates LLC2002-01-22Not AvailableUs
Topcare Ibuprofentablet, coated200 mgoralTopco Associates LLC2006-04-10Not AvailableUs
Topcare Childrens Ibuprofensuspension100 mg/5mLoralTopco Associates LLC2002-07-30Not AvailableUs
Topcare Ibuprofentablet, film coated200 mgoralTopco Associates LLC1993-04-22Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralTOP CARE (Topco Associates LLC)2013-04-30Not AvailableUs
Ibuprofentablet, coated200 mgoralTOP CARE (Topco Associates LLC)2013-04-30Not AvailableUs
Ibuprofentablet200 mgoralTOP CARE (Topco Associates LLC)2014-02-28Not AvailableUs
Ibuprofentablet, coated200 mgoralTOP CARE (Topco Associates LLC)2014-04-30Not AvailableUs
Topcare Ibuprofensuspension/ drops50 mg/1.25mLoralTopco Associates LLC2004-09-10Not AvailableUs
Topcare Ibuprofen Junior Strengthtablet, chewable100 mgoralTopco Associates LLC2004-05-28Not AvailableUs
Topcare Ibuprofentablet, film coated200 mgoralTopco Associates LLC2006-04-28Not AvailableUs
Topcare Ibuprofentablet200 mgoralTopco Associates LLC1988-02-15Not AvailableUs
Topcare Ibuprofentablet, coated200 mgoralTopco Associates LLC1988-11-15Not AvailableUs
Topcare Childrens Ibuprofensuspension100 mg/5mLoralTopco Associates LLC2002-07-02Not AvailableUs
Topcare Ibuprofen childrensliquid100 mg/5mLoralTopco Associates LLC1995-02-03Not AvailableUs
Topcare Ibuprofensuspension100 mg/5mLoralTopco Associates LLC1998-12-31Not AvailableUs
Ibuprofentablet, coated200 mgoralShopko Stores Operating Co., LLC2013-08-19Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralShopko Stores Operating Co., LLC.2010-07-09Not AvailableUs
Infants Ibuprofensuspension/ drops50 mg/1.25mLoralShopko Stores Operating Co., LLC2013-07-30Not AvailableUs
Ibuprofentablet, film coated200 mgoralShopko Stores Operating Co., LLC2013-09-09Not AvailableUs
Junior Strength Ibuprofentablet, chewable100 mgoralShopko Stores Operating Co., LLC2013-07-30Not AvailableUs
Ibuprofentablet, chewable100 mgoralShopko Stores Operating Co., LLC2013-08-06Not AvailableUs
Ibuprofentablet, film coated200 mgoralShopko Stores Operating Co., LLC2013-09-09Not AvailableUs
Ibuprofentablet, coated200 mgoralShopko Stores Operating Co., LLC2013-09-12Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralShopko Stores Operating Co., LLC2013-07-30Not AvailableUs
Leader Ibuprofensuspension100 mg/5mLoralCardinal Health2002-05-08Not AvailableUs
Leader Ibuprofen Childrenssuspension100 mg/5mLoralCardinal Health2002-04-25Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralCardinal Health2012-04-09Not AvailableUs
Leader Ibuprofentablet, coated200 mgoralCardinal Health1990-05-15Not AvailableUs
Leader Ibuprofentablet, coated200 mgoralCardinal Health2006-03-10Not AvailableUs
Leader Ibuprofentablet, film coated200 mgoralCardinal Health1990-05-15Not AvailableUs
Leader Ibuprofentablet, chewable100 mgoralCardinal Health2004-05-28Not AvailableUs
Leader Ibuprofensuspension/ drops50 mg/1.25mLoralCardinal Health2004-07-19Not AvailableUs
Leader Ibuprofentablet, film coated200 mgoralCardinal Health1990-10-15Not AvailableUs
Leader Ibuprofensuspension100 mg/5mLoralCardinal Health1999-01-28Not AvailableUs
Leader Ibuprofen Infantssuspension50 mg/1.25mLoralCardinal Health1999-09-30Not AvailableUs
Leader Ibuprofensuspension100 mg/5mLoralCardinal Health2002-04-25Not AvailableUs
Ibuprofentablet200 mgoralCardinal Health1988-05-24Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralCardinal Health (Leader)2012-12-11Not AvailableUs
Leader Ibuprofenliquid100 mg/5mLoralCardinal Health2008-10-16Not AvailableUs
Leader Ibuprofentablet, chewable100 mgoralCardinal Health1990-11-15Not AvailableUs
Ibuprofen infantssuspension50 mg/1.25mLoralH E B2002-06-18Not AvailableUs
Rx Act Ibuprofen childrenssuspension100 mg/5mLoralH E B2002-06-10Not AvailableUs
Rx Act Ibuprofentablet, film coated200 mgoralH E B1994-02-04Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralH E B2013-01-08Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralH E B2002-06-19Not AvailableUs
Junior Strength Ibuprofentablet, chewable100 mgoralH E B2010-09-01Not AvailableUs
Ibuprofensuspension/ drops50 mg/1.25mLoralH E B2005-02-25Not AvailableUs
Ibuprofen Childrenssuspension100 mg/5mLoralH E B2002-06-10Not AvailableUs
Ibuprofencapsule, coated200 mgoralH E B2002-04-08Not AvailableUs
Rx Act Ibuprofentablet, film coated200 mgoralH E B2006-07-04Not AvailableUs
Ibuprofentablet, film coated200 mgoralH E B1989-02-15Not AvailableUs
Ibuprofentablet, coated200 mgoralH E B1991-08-09Not AvailableUs
Rx Act Ibuprofensuspension100 mg/5mLoralH E B2002-06-19Not AvailableUs
Ibuprofentablet, film coated200 mgoralH E B2006-07-04Not AvailableUs
Rx Act Ibuprofen childrenssuspension100 mg/5mLoralH E B1999-01-06Not AvailableUs
Ibuprofentablet200 mgoralH E B1988-05-24Not AvailableUs
Ibuprofencapsule, coated200 mgoralH E B1988-05-24Not AvailableUs
Equaline Ibuprofensuspension50 mg/1.25mLoralSupervalu Inc2004-09-07Not AvailableUs
Equaline Ibuprofentablet, coated200 mgoralSupervalu Inc2006-03-07Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralSuper Valu (Equaline)2010-08-24Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralSuper Valu (Equaline)2010-07-08Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralSuper Valu (Equaline)2010-07-09Not AvailableUs
Equaline Ibuprofen childrenssuspension100 mg/5mLoralSupervalu Inc2004-10-07Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralEqualine (Super Valu)2012-01-10Not AvailableUs
Equaline Ibuprofensuspension/ drops50 mg/1.25mLoralSupervalu Inc2004-12-22Not AvailableUs
Ibuprofentablet, film coated200 mgoralSUPERVALU INC.1988-05-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralSUPERVALU INC.2002-03-30Not AvailableUs
Ibuprofentablet200 mgoralSUPERVALU INC.2002-04-08Not AvailableUs
Equaline Ibuprofentablet, film coated200 mgoralSupervalu Inc2006-04-28Not AvailableUs
Equaline Ibuprofentablet, chewable100 mgoralSupervalu Inc2011-05-04Not AvailableUs
Equaline Ibuprofentablet200 mgoralSupervalu Inc2004-08-05Not AvailableUs
Equaline Ibuprofentablet, coated200 mgoralSupervalu Inc2004-08-17Not AvailableUs
Equaline Ibuprofen childrenssuspension100 mg/5mLoralSupervalu Inc2004-09-24Not AvailableUs
Equaline Ibuprofensuspension100 mg/5mLoralSupervalu Inc2010-09-27Not AvailableUs
Equaline Ibuprofen childrenssuspension100 mg/5mLoralSupervalu Inc2004-08-30Not AvailableUs
Equaline Childrens Ibuprofensuspension100 mg/5mLoralSupervalu Inc2004-09-24Not AvailableUs
Shoprite Ibuprofen Ibtablet, coated200 mgoralWakefern Food Corporation2013-08-06Not AvailableUs
Shoprite Childrens Ibuprofensuspension100 mg/5mLoralWakefern Food Corporation2013-08-19Not AvailableUs
Shoprite Infants Ibuprofensuspension/ drops50 mg/1.25mLoralWakefern Food Corporation2013-06-17Not AvailableUs
Shoprite Ibuprofen Ibtablet, chewable100 mgoralWakefern Food Corporation2013-07-02Not AvailableUs
Shoprite Ibuprofen Ibtablet, film coated200 mgoralWakefern Food Corporation2013-08-06Not AvailableUs
Shoprite Ibuprofentablet, film coated200 mgoralWakefern Food Corporation2013-08-06Not AvailableUs
Shoprite Ibuprophentablet, coated200 mgoralWakefern Food Corporation2013-08-06Not AvailableUs
Shoprite Childrens Ibuprofensuspension100 mg/5mLoralWakefern Food Corporation2013-06-20Not AvailableUs
Shoprite Ibuprofensuspension100 mg/5mLoralWakefern Food Corporation2014-05-12Not AvailableUs
Ibuprofen infantssuspension50 mg/1.25mLoralMeijer Distribution Inc2000-03-17Not AvailableUs
Ibuprofentablet, coated200 mgoralMeijer Distribution Inc2006-06-21Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralMEIJER, INC.2010-07-12Not AvailableUs
Ibuprofensuspension/ drops50 mg/1.25mLoralMeijer Distribution Inc2004-04-18Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralMeijer Distribution Inc2014-04-23Not AvailableUs
Ibuprofen junior strengthtablet, chewable100 mgoralMeijer Distribution Inc2004-05-02Not AvailableUs
Ibuprofentablet, film coated200 mgoralMeijer Distribution Inc2006-04-26Not AvailableUs
Ibuprofentablet100 mgoralMeijer Distribution Inc2009-05-27Not AvailableUs
Ibuprofentablet200 mgoralMeijer Distribution Inc1988-02-15Not AvailableUs
Ibuprofentablet, coated200 mgoralMeijer Distribution Inc1988-11-15Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralMeijer Distribution Inc2002-03-19Not AvailableUs
Childrens Ibuprofenliquid100 mg/5mLoralMeijer Distribution Inc1994-11-21Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralMeijer Distribution Inc1999-01-05Not AvailableUs
Childrens Ibuprofen Oral Suspensionsuspension100 mg/5mLoralMeijer Distribution Inc2002-03-19Not AvailableUs
Ibuprofentablet200 mgoralMeijer1988-05-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralMeijer2002-04-08Not AvailableUs
Ibuprofentablet, film coated200 mgoralMeijer Distribution Inc1993-04-01Not AvailableUs
Ibuprofentablet, coated200 mgoralHannaford Brothers Company2006-05-31Not AvailableUs
Ibuprofensuspension/ drops50 mg/1.25mLoralHannaford Brothers Company2005-03-16Not AvailableUs
Ibuprofentablet, chewable100 mgoralHannaford Brothers Company2004-06-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralHannaford Brothers Company1995-06-29Not AvailableUs
Ibuprofentablet, coated200 mgoralHannaford Brothers Company1995-06-01Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralHannaford Brothers Company2009-05-06Not AvailableUs
Ibuprofensuspension100 mg/5mLoralHannaford Brothers Company1999-02-04Not AvailableUs
Care One Ibuprofen infantssuspension50 mg/1.25mLoralAmerican Sales Company2004-05-11Not AvailableUs
Care One Ibuprofen Ibtablet, coated200 mgoralAmerican Sales Company2006-05-09Not AvailableUs
Care One Ibuprofen childrenssuspension100 mg/5mLoralAmerican Sales Company2004-04-28Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralCare One (American Sales Company)2013-03-15Not AvailableUs
Care One Ibuprofensuspension/ drops50 mg/1.25mLoralAmerican Sales Company2006-05-16Not AvailableUs
Care One Ibuprofentablet, chewable100 mgoralAmerican Sales Company2004-09-13Not AvailableUs
Care One Ibuprofen Ibtablet, film coated200 mgoralAmerican Sales Company2006-05-24Not AvailableUs
Care One Ibuprofen Junior Strengthtablet, chewable100 mgoralAmerican Sales Company2010-05-21Not AvailableUs
Careone Ibuprofen Junior Strengthtablet, chewable100 mgoralAmerican Sales Company2010-05-21Not AvailableUs
Care One Ibuprofentablet200 mgoralAmerican Sales Company2004-04-13Not AvailableUs
Care One Ibuprofentablet, coated200 mgoralAmerican Sales Company2004-04-13Not AvailableUs
Care One Ibuprofen childrenssuspension100 mg/5mLoralAmerican Sales Company2004-05-04Not AvailableUs
Care One Ibuprofen childrensliquid100 mg/5mLoralAmerican Sales Company2008-08-01Not AvailableUs
Care One Ibuprofensuspension100 mg/5mLoralAmerican Sales Company2004-04-28Not AvailableUs
Good Sense Ibuprofen childrenssuspension100 mg/5mLoralRebel Distributors Corp1999-01-07Not AvailableUs
Ibuprofentablet200 mgoralRebel Distributors Corp2011-01-27Not AvailableUs
Ibuprofentablet, film coated200 mgoralRebel Distributors Corp2004-01-01Not AvailableUs
Ibuprofen infantssuspension50 mg/1.25mLoralHy Vee Inc2000-09-03Not AvailableUs
Ibuprofen Ibtablet, coated200 mgoralHy Vee Inc2006-05-14Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralHy Vee2013-04-13Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralHy Vee Inc2002-05-13Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralHy Vee2013-01-15Not AvailableUs
Ibuprofensuspension/ drops50 mg/1.25mLoralHy Vee Inc2005-02-26Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralHy Vee2015-01-31Not AvailableUs
Ibuprofentablet, chewable100 mgoralHy Vee Inc2005-02-12Not AvailableUs
Ibuprofen Ibtablet, film coated200 mgoralHy Vee Inc2006-05-21Not AvailableUs
Ibuprofentablet, film coated200 mgoralHy Vee Inc1991-03-15Not AvailableUs
Ibuprofentablet, coated200 mgoralHy Vee Inc1989-07-15Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralHy Vee Inc2002-04-01Not AvailableUs
Ibuprofenliquid100 mg/5mLoralHy Vee Inc1997-09-30Not AvailableUs
Ibuprofensuspension100 mg/5mLoralHy Vee Inc1999-03-05Not AvailableUs
Ibuprofensuspension50 mg/1.25mLoralPerrigo New York Inc2014-04-09Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralPerrigo New York Inc2014-04-09Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralPerrigo New York Inc2014-04-09Not AvailableUs
Ibuprofensuspension100 mg/5mLoralPerrigo New York Inc2011-11-17Not AvailableUs
Aprofen REGULAR STRENGTHtablet200 mgoralA P J Laboratories Limited2013-02-21Not AvailableUs
Good Neighbor Pharmacy Ibuprofentablet100 mgoralAmerisource Bergen2009-10-19Not AvailableUs
Good Neighbor Pharmacy Childrens Ibuprofensuspension100 mg/5mLoralAmerisource Bergen2002-04-02Not AvailableUs
Ibuprofentablet, film coated200 mgoralSave A Lot Food Stores, Ltd.1988-05-24Not AvailableUs
Being Well Ibuprofensuspension100 mg/5mLoralSave A Lot Food Stores Ltd2006-02-25Not AvailableUs
Green Guard Ibupro Relieftablet, film coated200 mgoralUnifirst First Aid Corporation2008-12-30Not AvailableUs
Medique Iprintablet, coated200 mgoralUnifirst First Aid Corporation2014-11-17Not AvailableUs
Otis Clapp Ultraprintablet, coated262 mgoralUnifirst First Aid Corporation2014-11-17Not AvailableUs
Medi-first Ibuprofentablet, coated200 mgoralUnifirst First Aid Corporation2014-11-17Not AvailableUs
Medi-first Plus Ibuprofentablet, coated200 mgoralUnifirst First Aid Corporation2014-11-17Not AvailableUs
Green Guard Ibuprofen Relieftablet, coated200 mgoralUnifirst First Aid2014-11-17Not AvailableUs
Dover Addaprintablet, coated262 mgoralUnifirst First Aid Corporation2014-11-17Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralWal Mart Stores, Inc.2012-05-17Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralWal Mart Stores, Inc.2012-05-17Not AvailableUs
Equate Ibuprofencapsule, liquid filled200 mgoralWalmart stores Inc2014-07-02Not AvailableUs
Equate Ibuprofen childrenssuspension100 mg/5mLoralWal Mart Stores Inc2002-04-16Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralEQUATE (Walmart Stores, Inc.)2012-12-11Not AvailableUs
Ibuprofentablet, coated200 mgoralEQUATE (Walmart Stores, Inc.)2013-12-30Not AvailableUs
Ibuprofencapsule, coated200 mgoralWal Mart Stores Inc2002-04-08Not AvailableUs
Ibuprofen Dye-Freetablet, film coated200 mgoralWal Mart Stores Inc2004-03-11Not AvailableUs
Equate Ibuprofentablet, chewable100 mgoralWal Mart Stores Inc2011-10-25Not AvailableUs
Equate Ibuprofentablet, film coated200 mgoralWal Mart Stores Inc2013-08-13Not AvailableUs
Equate Ibuprofentablet200 mgoralWal Mart Stores Inc1989-10-15Not AvailableUs
Equate Ibuprofentablet, coated200 mgoralWal Mart Stores Inc1989-09-15Not AvailableUs
Equate Ibuprofen childrenssuspension100 mg/5mLoralWal Mart Stores Inc2010-08-19Not AvailableUs
Equate Ibuprofensuspension100 mg/5mLoralWal Mart Stores Inc1999-02-02Not AvailableUs
Ibuprofentablet, film coated200 mgoralWal Mart Stores Inc1988-05-24Not AvailableUs
Help I Have An Aching Bodytablet200 mgoralHelp Remedies, Inc.2009-07-01Not AvailableUs
Sunmark Ibuprofentablet, coated200 mgoralMc Kesson2003-06-24Not AvailableUs
Sunmark Ibuprofen childrenssuspension100 mg/5mLoralMc Kesson2003-09-19Not AvailableUs
Sunmark Ibuprofensuspension100 mg/5mLoralMc Kesson2003-09-19Not AvailableUs
Sunmark Ibuprofen infantssuspension50 mg/1.25mLoralMc Kesson2003-08-28Not AvailableUs
Sunmark Ibuprofen childrenssuspension100 mg/5mLoralMc Kesson2003-09-06Not AvailableUs
Sunmark Ibuprofen childrenssuspension100 mg/5mLoralMc Kesson2003-06-24Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralMcKesson (Sunmark)2010-07-09Not AvailableUs
Sunmark Ibuprofen Ibtablet, chewable100 mgoralMc Kesson2004-07-10Not AvailableUs
Sunmark Ibuprofensuspension/ drops50 mg/1.25mLoralMc Kesson2004-04-29Not AvailableUs
Sunmark Ibuprofentablet, film coated200 mgoralMc Kesson2003-06-24Not AvailableUs
Sunmark Ibuprofen Ibtablet, film coated200 mgoralMc Kesson2006-04-28Not AvailableUs
Sunmark Ibuprofen childrensliquid100 mg/5mLoralMc Kesson2009-04-01Not AvailableUs
Sunmark Ibuprofen Ibtablet, coated200 mgoralMc Kesson2006-03-20Not AvailableUs
Ibuprofentablet, film coated200 mgoralMedicine Shoppe International Inc1988-03-15Not AvailableUs
Ibuprofentablet, coated200 mgoralMedicine Shoppe International Inc1990-02-15Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralMedicine Shoppe International Inc1999-01-09Not AvailableUs
Smart Sense Ibuprofen infantssuspension50 mg/1.25mLoralKmart Corporation2010-07-01Not AvailableUs
Smart Sense Ibuprofentablet, coated200 mgoralKmart Corporation2010-06-21Not AvailableUs
Smart Sense Ibuprofensuspension100 mg/5mLoralKmart Corporation2010-05-20Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralSMART SENSE (Kmart)2012-09-30Not AvailableUs
Smart Sense Ibuprofensuspension/ drops50 mg/1.25mLoralKmart Corporation2010-05-14Not AvailableUs
Smart Sense Ibuprofentablet, chewable100 mgoralKmart Corporation2010-06-24Not AvailableUs
Smart Sense Ibuprofen gluten freetablet, film coated200 mgoralKmart Corporation2010-06-18Not AvailableUs
Smart Sense Ibuprofentablet, film coated200 mgoralKmart Corporation2010-06-04Not AvailableUs
Smart Sense Ibuprofentablet, coated200 mgoralKmart Corporation2010-06-17Not AvailableUs
Smart Sense Ibuprofenliquid100 mg/5mLoralKmart Corporation2010-05-20Not AvailableUs
Smart Sense Ibuprofensuspension100 mg/5mLoralKmart Corporation2010-05-20Not AvailableUs
Leader Childrens Ibuprofensuspension100 mg/5mLoralCardinal Health2002-05-08Not AvailableUs
Leader Childrens Ibuprofensuspension100 mg/5mLoralCardinal Health2014-03-05Not AvailableUs
Leader Childrens Ibuprofensuspension100 mg/5mLoralCardinal Health2002-04-25Not AvailableUs
Leader Ibuprofen 200tablet200 mgoralCardinal Health2014-07-23Not AvailableUs
Probufentablet400 mg/537mgoralSAMSUNG PHARM IND. CO., LTD.2011-12-01Not AvailableUs
Ibuprofentablet, film coated200 mgoralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2012-02-16Not AvailableUs
Proprinaltablet, sugar coated200 mgoralNor Med1990-06-01Not AvailableUs
Ibuprofentablet200 mgoralHART Health1987-06-03Not AvailableUs
Infants Motrinsuspension/ drops50 mg/1.25mLoralMc Neil Consumer Healthcare Div Mc Neil Ppc, Inc2004-06-01Not AvailableUs
Motrin Ibtablet, film coated200 mgoralMc Neil Consumer Healthcare Div Mc Neil Ppc, Inc2000-08-01Not AvailableUs
Childrens Motrinsuspension100 mg/5mLoralMc Neil Consumer Healthcare Div. Mc Neil Ppc, Inc2001-09-01Not AvailableUs
Motrin Infantssuspension/ drops50 mg/1.25mLoralMc Neil Consumer Healthcare Div Mc Neil Ppc, Inc2001-09-01Not AvailableUs
Motrin Ibcapsule, liquid filled200 mgoralMc Neil Consumer Healthcare Div Mc Neil Ppc, Inc2015-01-26Not AvailableUs
Childrens Motrinsuspension100 mg/5mLoralMc Neil Consumer Healthcare Div. Mc Neil Ppc, Inc1995-09-01Not AvailableUs
Ibuprofentablet200 mgoralGeiss, Destin & Dunn, Inc (Goodsense)2011-12-22Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralGood Sense (Geiss, Destin & Dunn, Inc.)2013-04-23Not AvailableUs
Ibuprofentablet, coated200 mgoralGood Sense (Geiss, Destin & Dunn, Inc.)2013-04-13Not AvailableUs
Ibuprofentablet, film coated200 mgoralL.N.K. International, Inc.1999-03-02Not AvailableUs
Ibuprofentablet, film coated200 mgoralL.N.K. International, Inc.1999-03-02Not AvailableUs
Ibuprofentablet, film coated200 mgoralL.N.K. International, Inc.1999-03-02Not AvailableUs
Ibuprofentablet, film coated200 mgoralL.N.K. International, Inc.1999-03-02Not AvailableUs
Ibuprofentablet, film coated200 mgoralL.N.K. International, Inc.1999-03-02Not AvailableUs
Ibuprofentablet, film coated200 mgoralL.N.K. International, Inc.1999-03-02Not AvailableUs
Ibuprofentablet, film coated200 mgoralL.N.K. International, Inc.1999-03-02Not AvailableUs
Ibuprofentablet200 mgoralL.N.K. International, Inc.1988-05-24Not AvailableUs
Babies R Us Infants Ibuprofensuspension/ drops50 mg/1.25mLoralToys"R"Us, Inc.2010-12-01Not AvailableUs
Babies R Us Ibuprofensuspension100 mg/5mLoralToys"R"Us, Inc.2010-12-01Not AvailableUs
Ibuprofentablet200 mgoralNew World Imports2012-06-05Not AvailableUs
Ibuprofentablet200 mgoralNew World Imports2010-09-10Not AvailableUs
Ibuprofentablet200 mgoralGenuine First Aid LLC2010-02-17Not AvailableUs
Ibuprofentablet, coated200 mgoralPolygen Pharmaceuticals LLC2012-06-05Not AvailableUs
Ibuprofentablet, coated200 mgoralPolygen Pharmaceuticals LLC2012-06-05Not AvailableUs
Ibuprofentablet200 mgoralPolygen Pharmaceuticals LLC2013-07-02Not AvailableUs
Pain Relieftablet200 mgoralSelect Corporation2012-10-15Not AvailableUs
Pain Relief Anti Inflammatorytablet200 mgoralSelect Corporation2012-10-15Not AvailableUs
Ibuprofentablet, film coated200 mgoralH.J. Harkins Company, Inc.1988-05-24Not AvailableUs
Ibuprofensuspension100 mg/5mLoralH.J. Harkins Company, Inc.1999-02-07Not AvailableUs
Clear Choice Ibuprofentablet200 mgoralAthlete's Needs Inc2012-10-09Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralLIVE BETTER (The Great Atlantic & Pacific Tea Company)2013-03-25Not AvailableUs
Ibuprofentablet200 mgoralMedline Industries2013-01-15Not AvailableUs
Ibuprofentablet200 mgoralMedline Industries, Inc.2014-09-08Not AvailableUs
Ibuprofen Pain Releiver/ Fever Reducertablet200 mgoralAmneal Pharmaceuticals of New York, LLC2009-12-16Not AvailableUs
Ibuprofen (NSAID) Pain Releiver/ Fever Reducertablet200 mgoralAmneal Pharmaceuticals2009-12-16Not AvailableUs
Ibuprofen Pain Releiver/ Fever Reducertablet200 mgoralAmneal Pharmaceuticals of New York, LLC2009-12-16Not AvailableUs
Ibuprofen (NSAID) Pain Releiver/ Fever Reducertablet200 mgoralAmneal Pharmaceuticals2009-12-16Not AvailableUs
Ibuprofentablet200 mgoralDiscount Drug Mart2013-06-20Not AvailableUs
Ibuprofen IMMEDIATE RELEASEtablet, coated200 mgoralDiscount Drug Mart2014-12-22Not AvailableUs
Ibuprofen IMMEDIATE RELEASEtablet, coated200 mgoralDiscount Drug Mart2014-12-22Not AvailableUs
Counteract IBtablet, film coated200 mgoralMelaleuca, Inc.2010-03-18Not AvailableUs
Counteract IBtablet, coated200 mgoralMelaleuca, Inc2011-04-30Not AvailableUs
Ibuprofentablet200 mgoralPhysicians Total Care, Inc.2007-10-16Not AvailableUs
Ibuprofensuspension100 mg/5mLoralPhysicians Total Care, Inc.2000-09-12Not AvailableUs
Ibuprofen Juniortablet, chewable100 mgoralPhysicians Total Care, Inc.2007-10-16Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralCardinal Health2004-04-13Not AvailableUs
Childrens Ibuprofensuspension200 mg/10mLoralCardinal Health2006-09-14Not AvailableUs
Ibuprofentablet200 mgoralArmy and Air Force Exchange Service1988-05-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralArmy and Air Force Exchange Service2002-03-30Not AvailableUs
Ibuprofencapsule, coated200 mgoralArmy and Air Force Exchange Service2002-04-08Not AvailableUs
Ibuprofen infantssuspension50 mg/1.25mLoralWestern Family Foods Inc2000-08-16Not AvailableUs
Ibuprofentablet200 mgoralWestern Family Foods, Inc.2011-02-01Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralWestern Family Foods Inc2002-10-07Not AvailableUs
Ibuprofentablet200 mgoralWestern Family Foods, Inc.2011-02-01Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralWestern Family Foods, Inc.2010-03-13Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralWestern Family Foods, Inc.2014-09-30Not AvailableUs
Ibuprofentablet200 mgoralWestern Family Foods, Inc.2011-12-15Not AvailableUs
Ibuprofentablet200 mgoralWestern Family Foods, Inc.2012-07-05Not AvailableUs
Ibuprofentablet, coated200 mgoralWestern Family Foods, Inc.2011-09-01Not AvailableUs
Ibuprofentablet, coated200 mgoralWestern Family Foods, Inc.2013-11-30Not AvailableUs
Ibuprofentablet, chewable100 mgoralWestern Family Foods Inc2004-09-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralWestern Family Foods Inc2006-05-31Not AvailableUs
Ibuprofentablet, chewable100 mgoralWestern Family Foods Inc2009-04-07Not AvailableUs
Ibuprofentablet200 mgoralWestern Family Foods Inc2001-09-05Not AvailableUs
Ibuprofentablet, coated200 mgoralWestern Family Foods Inc2001-09-05Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralWestern Family Foods Inc2002-10-14Not AvailableUs
Childrens Ibuprofenliquid100 mg/5mLoralWestern Family Foods Inc2008-08-18Not AvailableUs
Ibuprofensuspension100 mg/5mLoralWestern Family Foods Inc1999-01-28Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralFreds Inc2012-07-02Not AvailableUs
Infants Ibuprofenliquid50 mg/1.25mLoralFred's Inc.2012-02-22Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralFreds Inc2013-04-13Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralFred's Inc.2008-03-24Not AvailableUs
Ibuprofentablet200 mgoralFRED'S, INC.1988-05-24Not AvailableUs
Ibuprofencapsule, coated200 mgoralFRED'S, INC.1988-05-24Not AvailableUs
Ibuprofencapsule, coated200 mgoralFRED'S, INC.2002-04-08Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralFred's Inc.2006-06-01Not AvailableUs
Healthy Accents Ibuprofen infantssuspension50 mg/1.25mLoralDZA Brands LLC2008-02-18Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralHealthy Accents (DZA Brands, LLC)2012-12-11Not AvailableUs
Healthy Accents Ibuprofen childrenssuspension100 mg/5mLoralDZA Brands LLC2008-03-03Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralHealthy Accents (DZA Brands, LLC)2013-04-15Not AvailableUs
Ibuprofentablet, coated200 mgoralHealthy Accents (DZA Brands, LLC)2013-12-30Not AvailableUs
Healthy Accents Ibuprofensuspension/ drops50 mg/1.25mLoralDZA Brands LLC2011-06-06Not AvailableUs
Healthy Accents Ibuprofentablet, film coated200 mgoralDZA Brands LLC2013-05-22Not AvailableUs
Healthy Accents Ibuprofentablet, chewable100 mgoralDZA Brands LLC2011-06-30Not AvailableUs
Healthy Accents Ibuprofentablet, film coated200 mgoralDZA Brands LLC2009-03-20Not AvailableUs
Healthy Accents Ibuprofentablet, film coated200 mgoralDZA Brands LLC2008-01-22Not AvailableUs
Healthy Accents Ibuprofentablet, coated200 mgoralDZA Brands LLC2008-05-17Not AvailableUs
Healthy Accents Ibuprofensuspension100 mg/5mLoralDZA Brands LLC2008-03-03Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralFamily Dollar Services Inc.2006-08-04Not AvailableUs
Ibuprofentablet, coated200 mgoralFamily Dollar (FAMILY WELLNESS)2014-06-30Not AvailableUs
Ibuprofentablet, coated200 mgoralFamily Dollar (FAMILY WELLNESS)2014-07-31Not AvailableUs
Infants Ibuprofensuspension50 mg/1.25mLoralFamily Dollar Services Inc.2012-02-22Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralFamily Dollar Services Inc.2012-02-23Not AvailableUs
Film Coated Ibuprofentablet200 mgoralFamily Dollar1988-05-24Not AvailableUs
Ibuprofencapsule, coated200 mgoralFamily Dollar1988-05-24Not AvailableUs
Ibuprofen Ibtablet200 mgoralFamily Dollar2002-04-08Not AvailableUs
Family Wellness Childrens Ibuprofensuspension100 mg/5mLoralFamily Dollar Services Inc2002-08-22Not AvailableUs
Moore Medical Llc Ibuprofentablet, film coated200 mgoralMoore Medical LLC2008-12-30Not AvailableUs
Dolextablet200 mgoralPharmadel LLC2013-03-25Not AvailableUs
Rexall Ibuprofentablet, film coated200 mgoralDolgencorp, LLC2013-08-07Not AvailableUs
Health Sense Infants Ibuprofen Oral Suspensionsuspension50 mg/1.25mLoralDolgencorp Inc2009-06-08Not AvailableUs
Dg Health Ibuprofentablet, coated200 mgoralDolgencorp, LLC2010-02-01Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralDolgencorp, Inc. (DOLLAR GENERAL & REXALL)2012-05-17Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralDolgencorp, Inc. (DOLLAR GENERAL & REXALL)2010-07-07Not AvailableUs
Dg Health Ibuprofensuspension/ drops50 mg/1.25mLoralDolgencorp, LLC2010-04-27Not AvailableUs
Ibuprofentablet, film coated200 mgoralDolgencorp, LLC1988-05-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralDolgencorp, LLC1999-03-02Not AvailableUs
Dg Health Ibuprofensuspension50 mg/1.25mLoralDolgencorp, LLC2010-02-22Not AvailableUs
Rexall Ibuprofentablet, film coated200 mgoralDolgencorp, LLC2012-09-06Not AvailableUs
Rexall Ibuprofentablet, chewable100 mgoralDolgencorp, LLC2010-09-14Not AvailableUs
Dg Health Ibuprofentablet200 mgoralDolgencorp, LLC2009-10-03Not AvailableUs
Rexall Ibuprofenliquid100 mg/5mLoralDolgencorp Inc2010-08-19Not AvailableUs
Dg Health Ibuprofensuspension100 mg/5mLoralDolgencorp Inc2010-02-06Not AvailableUs
Rexall Ibuprofentablet, film coated200 mgoralDolgencorp Inc2012-08-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralDolgencorp, LLC2002-03-30Not AvailableUs
Profen Ib infantssuspension50 mg/1.25mLoralPublix Super Markets Inc2001-06-29Not AvailableUs
Ibuprofentablet, coated200 mgoralPublix Super Markets Inc2006-03-22Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralPublix Supermarkets, Inc.2012-07-03Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralPublix Supermarkets, Inc.2012-07-03Not AvailableUs
Profen Ibsuspension100 mg/5mLoralPublix Super Markets Inc2003-11-18Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralPublix Supermarkets, Inc.2013-04-30Not AvailableUs
Ibuprofensuspension/ drops50 mg/1.25mLoralPublix Super Markets Inc2011-09-09Not AvailableUs
Ibuprofentablet, chewable100 mgoralPublix Super Markets Inc2004-10-28Not AvailableUs
Ibuprofentablet, film coated200 mgoralPublix Super Markets Inc2006-05-03Not AvailableUs
Ibuprofentablet, film coated200 mgoralPublix Super Markets Inc1988-09-15Not AvailableUs
Ibuprofentablet, coated200 mgoralPublix Super Markets Inc1988-09-15Not AvailableUs
Profen Ib childrenssuspension100 mg/5mLoralPublix Super Markets Inc2001-09-13Not AvailableUs
Ibuprofentablet200 mgoralSalado Sales, Inc.1988-05-24Not AvailableUs
Ibuprofentablet, coated200 mgoralAAA Pharmaceutical, Inc.2012-12-04Not AvailableUs
Ibuprofentablet, coated200 mgoralAAA Pharmaceutical, Inc.2012-12-04Not AvailableUs
Ibuprofentablet, coated200 mgoralAAA Pharmaceutical, Inc.2012-12-04Not AvailableUs
Ibuprofentablet, coated200 mgoralAAA Pharmaceutical, Inc.2012-12-04Not AvailableUs
Ibuprofentablet, film coated200 mgoralGeri Care Pharmaceutical Corp2004-01-01Not AvailableUs
Ibuprofentablet, coated200 mgoralShasun Pharmaceuticals Limited2011-04-04Not AvailableUs
Ibuprofentablet, coated200 mgoralShasun Pharmaceuticals Limited2011-04-28Not AvailableUs
Ibuprofentablet, coated200 mgoralShasun Pharmaceuticals Limited2011-04-04Not AvailableUs
Ibuprofentablet, coated200 mgoralShasun Pharmaceuticals Limited2011-03-28Not AvailableUs
Ibuprofentablet, film coated200 mgoralClinical Solutions Wholesale1988-05-24Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralJ.P BUSINESS ENTERPRISE2013-08-20Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralP And L Development Of New York Corporation (Ready In Case)2014-07-31Not AvailableUs
Pain Relieftablet, coated200 mgoralP and L Development of New York Corporation2012-08-13Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralPL Developments2012-05-17Not AvailableUs
Pain Relieftablet, coated200 mgoralP and L Development of New York Corporation2012-09-28Not AvailableUs
Ibuprofentablet, coated200 mgoralP & L Development, LLC2014-11-30Not AvailableUs
Pain Relieftablet200 mgoralP and L Development of New York Corporation2013-11-30Not AvailableUs
Ibuprofentablet, coated200 mgoralP And L Development Of New York Corporation (Ready In Case)2014-02-28Not AvailableUs
Ibuprofentablet, chewable100 mgoralCVS Pharmacy2004-05-07Not AvailableUs
Ibuprofentablet, coated200 mgoralCVS Pharmacy2006-02-17Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralCVS Pharmacy2014-07-31Not AvailableUs
Cvs Pharmacy Ibuprofencapsule, liquid filled200 mgoralCVS Pharmacy2009-12-04Not AvailableUs
Ibuprofensuspension100 mg/5mLoralCVS Pharmacy2002-08-27Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralCVS Pharmacy2012-09-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1988-05-24Not AvailableUs
Ibuprofentablet, coated200 mgoralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1988-05-24Not AvailableUs
Ibuprofensuspension/ drops50 mg/1.25mLoralCVS Pharmacy2004-05-07Not AvailableUs
Ibuprofentablet, film coated200 mgoralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1999-03-02Not AvailableUs
Ibuprofen Ibtablet, coated200 mgoralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED2002-04-08Not AvailableUs
Dye Free Ibuprofentablet200 mgoralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED2004-03-11Not AvailableUs
Ibuprofentablet, film coated200 mgoralCVS Pharmacy2006-04-27Not AvailableUs
Ibuprofentablet, chewable100 mgoralCVS Pharmacy1991-11-05Not AvailableUs
Ibuprofentablet200 mgoralCVS Pharmacy2001-07-10Not AvailableUs
Ibuprofentablet, coated200 mgoralCVS Pharmacy2001-07-31Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralCVS Pharmacy2002-09-04Not AvailableUs
Ibuprofenliquid100 mg/5mLoralCVS Pharmacy2009-06-30Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralCVS Pharmacy2014-02-09Not AvailableUs
Ibuprofen childrenssuspension100 mg/5mLoralCVS Pharmacy1999-01-07Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralCVS Pharmacy2014-01-29Not AvailableUs
Infants Ibuprofensuspension50 mg/1.25mLoralCVS Pharmacy1999-11-08Not AvailableUs
Conney Ibuprofentablet, film coated200 mgoralConney Safety Products, LLC2011-11-142015-04-01Us
Direct Safety Ibuprofentablet, coated200 mgoralConney Safety Products, LLC2014-11-17Not AvailableUs
Direct Safety Ibuprofentablet, film coated200 mgoralConney Safety Products, LLC2013-05-03Not AvailableUs
Ibuprofentablet200 mgoralKinray2011-11-22Not AvailableUs
Preferred Plus Ibuprofen 200tablet200 mgoralKinray2013-06-26Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralPreferred Plus (Kinray)2010-08-30Not AvailableUs
Preferred Plus Ibuprofentablet, film coated200 mgoralKinray, Inc.2013-05-11Not AvailableUs
Ibuprofentablet200 mgoralKinray2011-07-25Not AvailableUs
Ibuprofentablet200 mgoralKinray2011-07-25Not AvailableUs
Childrens Ibuprofensolution100 mg/5mLoralPreferred Plus (Kinray)2014-06-01Not AvailableUs
Health Mart Ibuprofensuspension/ drops50 mg/1.25mLoralMc Kesson2011-11-21Not AvailableUs
Health Mart Childrens Ibuprofensuspension100 mg/5mLoralMc Kesson2011-11-29Not AvailableUs
Health Mart Ibuprofensuspension100 mg/5mLoralMc Kesson2011-11-21Not AvailableUs
Health Mart Ibuprofensuspension50 mg/1.25mLoralMc Kesson2011-11-21Not AvailableUs
Health Mart Ibuprofentablet, coated200 mgoralMc Kesson2011-11-21Not AvailableUs
Health Mart Ibuprofentablet, film coated200 mgoralMc Kesson2011-11-21Not AvailableUs
Health Mart Ibuprofentablet, coated200 mgoralMc Kesson2011-11-21Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralMc Kesson (Health Mart)2012-04-09Not AvailableUs
Health Mart Ibuprofensuspension100 mg/5mLoralMc Kesson2011-11-21Not AvailableUs
Health Mart Ibuprofen Ibtablet, film coated200 mgoralMc Kesson2013-10-26Not AvailableUs
Health Mart Childrens Ibuprofenliquid100 mg/5mLoralMc Kesson2013-08-13Not AvailableUs
Health Mart Ibuprofen Ibtablet, coated200 mgoralMc Kesson2011-11-21Not AvailableUs
Health Sense Proviltablet, film coated200 mgoralPrime Marketing, LLC2006-01-01Not AvailableUs
Ibuprofentablet200 mgoralGranules India Limited2011-01-01Not AvailableUs
Ibuprofentablet200 mgoralGranules India Limited2011-01-01Not AvailableUs
Ibuprofen (nsaid) Pain Reliever/fever Reducertablet200 mgoralA&Z Pharmaceutical, Inc.2011-04-30Not AvailableUs
Ibuprofen (nsaid) Pain Reliever/fever Reducercapsule200 mgoralA&Z Pharmaceutical, Inc.2011-04-30Not AvailableUs
Pediacare Infantsliquid50 mg/1.25mLoralMedtech Products Inc.2011-10-15Not AvailableUs
Pediacare Childrenssuspension100 mg/5mLoralMedtech Products Inc.2011-01-12Not AvailableUs
Ibuprofentablet200 mgoralProficient Rx LP2011-01-27Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralProficient Rx LP2006-06-01Not AvailableUs
Ibuprofentablet, coated200 mgoralAvema Pharma Solutions2013-08-01Not AvailableUs
Ibuprofentablet, coated200 mgoralAvema Pharma Solutions2013-08-01Not AvailableUs
Ibuprofentablet, coated200 mgoralAvema Pharma Solutions2013-08-01Not AvailableUs
Ibuprofentablet, coated200 mgoralAvema Pharma Solutions2013-08-01Not AvailableUs
Ibuprofentablet, sugar coated200 mgoralMc Kesson Packaging Services Business Unit Of Mc Kesson Corporation2005-01-10Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralKinray Inc.2006-06-01Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralKinray Inc.2006-06-01Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralKinray Inc.2006-06-01Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralKinray Inc.2006-06-01Not AvailableUs
Infants Ibuprofensuspension50 mg/1.25mLoralChain Drug Marketing Association Inc.2009-11-01Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralChain Drug Marketing Association Inc.2010-03-04Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralChain Drug Marketing Association Inc.2006-10-09Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralChain Drug Marketing Association Inc.2008-01-10Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralQUALITY CHOICE (Chain Drug Marketing Association)2013-03-11Not AvailableUs
Ibuprofentablet200 mgoralChain Drug Marketing Association Inc1988-05-24Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralChain Drug Marketing Association Inc.2014-10-10Not AvailableUs
Ibuprofen Ibtablet, coated200 mgoralChain Drug Marketing Association2007-05-11Not AvailableUs
Ibuprofen Ibtablet, coated200 mgoralChain Drug Marketing Association2007-05-11Not AvailableUs
Ibuprofen Ibtablet, coated200 mgoralChain Drug Marketing Association2014-05-14Not AvailableUs
Ibuprofen Ibtablet, coated200 mgoralChain Drug Marketing Association2014-05-14Not AvailableUs
Quality Choice Ibuprofen 200tablet200 mgoralChain Drug Marketing Association2014-07-23Not AvailableUs
Ibuprofentablet, film coated200 mgoralChain Drug Marketing Association Inc1988-05-24Not AvailableUs
Ibuprofentablet, coated200 mgoralChain Drug Marketing Association2012-08-27Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralHarmon Stores2014-08-31Not AvailableUs
Harmon Face Values Ibuprofensuspension100 mg/5mLoralHarmon Stores Inc.2011-12-18Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralValu Merchandisers Company (Best Choice)2012-06-19Not AvailableUs
Infants Ibuprofenliquid50 mg/1.25mLoralValu Merchandisers Company2009-10-02Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralBest Choice (Valu Merchandisers Company)2010-08-21Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralValu Merchandisers Company2006-10-09Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralValu Merchandisers Company2012-05-23Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralValu Merchandisers Company2008-01-16Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralCostco Wholesale2010-07-08Not AvailableUs
Ibuprofentablet, film coated200 mgoralCostco Wholesale Corporation1988-05-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralCostco Wholesale Corporation1999-03-02Not AvailableUs
Kirkland Signature Ibuprofen Ibtablet, film coated200 mgoralCostco Wholesale Company2007-06-22Not AvailableUs
Kirkland Signature Ibuprofentablet, film coated200 mgoralCostco Wholesale Company2003-06-25Not AvailableUs
Welby Health Ibuprofentablet200 mgoralAldi, Inc1993-06-01Not AvailableUs
Welby Health Ibuprofenliquid100 mg/5mLoralAldi, Inc2009-12-09Not AvailableUs
Film Coated Ibuprofentablet200 mgoralGREAT LAKES WHOLESALE, MARKETING, & SALES, INC.1988-05-24Not AvailableUs
Ibuprofencapsule, coated200 mgoralGREAT LAKES WHOLESALE, MARKETING, & SALES, INC.1988-05-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralTYA Pharmaceuticals1988-05-24Not AvailableUs
Ibuprofen Pain Reliever/Fever Reducercapsule, liquid filled200 mgoralAmneal Pharmaceuticals2013-03-29Not AvailableUs
Ibuprofen Pain Reliever/ Fever Reducersuspension100 mg/5mLoralAmneal Pharmaceuticals2011-11-12Not AvailableUs
Ibuprofen Pain Reliever/fever Reducercapsule, liquid filled200 mgoralAmneal Pharmaceuticals of New York, LLC2011-12-23Not AvailableUs
Ibuprofentablet200 mgoralSDA Laboratories, Inc.2011-01-27Not AvailableUs
Circle K Ibuprofentablet, coated200 mgoralLil' Drug Store Products, Inc2014-11-01Not AvailableUs
Adviltablet, coated200 mgoralLil' Drug Store Products, Inc.2010-02-22Not AvailableUs
Motrin Ibtablet, coated200 mgoralLil' Drug Store Products, Inc.2010-05-10Not AvailableUs
Lil Drug Store Ibuprofentablet200 mgoralLil' Drug Store Products, Inc.2011-01-27Not AvailableUs
Advil Liquigelscapsule, liquid filled200 mgoralLil' Drug Store Products, Inc2012-05-01Not AvailableUs
Ibuprofentablet200 mgoralContract Pharmacy Services Pa2010-08-16Not AvailableUs
Ibuprofentablet200 mgoralContract Pharmacy Services Pa2010-08-02Not AvailableUs
Ibuprofentablet, coated200 mgoralWin Co Foods, Llc2014-12-15Not AvailableUs
Ibuprofentablet, coated200 mgoralWin Co Foods, Llc2014-12-15Not AvailableUs
Ibuprofen Ibtablet, coated200 mgoralWin Co Foods, Llc2014-12-15Not AvailableUs
Ibuprofen Ibtablet, coated200 mgoralWin Co Foods, Llc2014-12-15Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralWin Co Foods, Llc2014-12-31Not AvailableUs
Ibuprofentablet200 mgoralChain Drug Consortium2014-11-04Not AvailableUs
Ibuprofen Capletcapsule200 mgoralChain Drug Consortium2014-11-04Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralPremier Value (Chain Drug Consortium, LLC)2010-07-08Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralPremier Value2012-12-06Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralPremier Value2006-06-01Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralPremier Value2006-06-01Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralPremier Value2006-06-01Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralPremier Value2006-06-01Not AvailableUs
Ibuprofentablet, film coated200 mgoralChain Drug Consortium LLC2013-05-07Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralPremier Value (Chain Drug Consortium, LLC)2014-12-31Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralPrecision Dose Inc.2004-04-13Not AvailableUs
Childrens Ibuprofensuspension200 mg/10mLoralPrecision Dose Inc.2006-09-14Not AvailableUs
Ibuprofentablet, film coated200 mgoralSam's West Inc1988-05-24Not AvailableUs
Simply Right Ibuprofentablet, film coated200 mgoralSam's West Inc2011-12-18Not AvailableUs
Ibuprofencapsule, liquid filled220 mgoralSPIRIT PHARMACEUTICALS,LLC2012-05-01Not AvailableUs
Good Sense Ibuprofentablet, chewable100 mgoralDispensing Solutions, Inc.2004-11-09Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralBJWC2012-09-01Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralBJWC (Berkley & Jensen / BJ's)2013-05-15Not AvailableUs
Childrens Ibuprofensuspension100 mg/5mLoralPreferred Pharmaceuticals, Inc2011-08-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralPreferred Pharmaceuticals, Inc.2014-01-02Not AvailableUs
Ibuprofen Childrenssuspension100 mg/5mLoralPreferred Pharmaceuticals, Inc2012-04-23Not AvailableUs
Ibuprofencapsule, liquid filled200 mgoralOUR FAMILY (Nash Finch Company)2013-04-30Not AvailableUs
Infants Ibuprofenliquid50 mg/1.25mLoralNash Finch Company (Our Family)2014-03-19Not AvailableUs
Childrens Ibuprofensolution100 mg/5mLoralNash Finch Company (Our Family)2006-07-18Not AvailableUs
Childrens Ibuprofensolution100 mg/5mLoralNash Finch Company (Our Family)2006-07-18Not AvailableUs
Ibuprofentablet200 mgoralNash Finch Company1988-05-24Not AvailableUs
Ibuprofencapsule, coated200 mgoralNash Finch Company1988-05-24Not AvailableUs
Ibuprofentablet, film coated200 mgoralNash Finch Company2002-03-30Not AvailableUs
Ibuprofencapsule, coated200 mgoralNash Finch Company2002-04-08Not AvailableUs
Ibuprofentablet, coated200 mgoralVelocity Pharma2012-07-01Not AvailableUs
Ibuprofentablet200 mgoralPharmascience IncNot AvailableNot AvailableCanada
Ibuprofentablet200 mgoralPharmascience IncNot AvailableNot AvailableCanada
International Brands
NameCompany
Act-3Healthcare Logistics
ActiprofenSterling Health
AdexDexxon
AdranNot Available
Advil Liqui-GelsWyeth
AktrenBayer
Alges-XAxapharm
AlgoflexChinoin
AlgofrenIntermed
AliviumBristol-Myers Squibb
ArtofenTeva
BetagesicAdcock Ingram Pharmaceuticals
BetaprofenBe-Tabs Pharmaceuticals
BlutonNot Available
BonifenKrka
BrufenAbbott
BuburoneTowa Yakuhin
BugesicNot Available
BuprovilNot Available
BuranaOrion
ButyleninNot Available
CalprofenMcNeil
Cap-ProfenPERRIGO
Children's AdvilPfizer
Children's ElixsurePfizer
Children's IbuprofenPfizer
Children's MotrinJohnson & Johnson
DalsyAbbott
DismenolMerz
DiverinNot Available
DolgiridNot Available
DolgitDolorgiet
DolofortNot Available
DolorazNot Available
DolorminNot Available
DorivalNot Available
EbufacNot Available
EmuProfenNot Available
EpobronNot Available
EspidifenNot Available
EveNot Available
FemadonNot Available
FenbidNot Available
FenpaedNot Available
FinalflexNot Available
GalprofenNot Available
HaltranNot Available
Herron BlueNot Available
i-profen Not Available
IbalginNot Available
Ibu-AttritinNot Available
IBU-RatiopharmNot Available
Ibu-VivimedNot Available
IbuflamNot Available
IbugelNot Available
IbugesicNot Available
IbuHEXALNot Available
IbuleveNot Available
IbumNot Available
IbumaxNot Available
IbumetinNot Available
IbumidolNot Available
IbupainNot Available
IbuprocinNot Available
IbupromNot Available
IbuprosynNot Available
IbuproxNot Available
IbustarNot Available
IbutidNot Available
IbuxNot Available
IbuxinNot Available
InabrinNot Available
InovenNot Available
IprenNot Available
Junior Strength MotrinNot Available
KratalginNot Available
LamidonNot Available
LebrufenNot Available
LiptanNot Available
LotemNot Available
MedicolNot Available
MediprenNot Available
Midol IBNot Available
MotrinNot Available
MynosedinNot Available
MypaidNot Available
MyprodolNot Available
NarfenNot Available
Naron Ace Not Available
NeobrufenNot Available
NobfenNot Available
NobgenNot Available
NorvectanNot Available
NuprinNot Available
NureflexNot Available
NurofenNot Available
OrbifenNot Available
PanafenNot Available
PediaprofenNot Available
PerifarNot Available
ProfinNot Available
RanfenNot Available
RapidolNot Available
RatiodolorNot Available
RimafenNot Available
RoideninNot Available
RufenNot Available
SalvarinaNot Available
SeclodinNot Available
SolpaflexNot Available
Speedpain NANONot Available
SpidifenZambon
SusprenNot Available
TabalonNot Available
TefinNot Available
TrendarNot Available
UnafenNot Available
UpfenNot Available
UremNot Available
Brand mixtures
Brand NameIngredients
Advil Cold & Sinusibuprofen + pseudoephedrine HCl
Advil Cold & Sinus Daytimeibuprofen + pseudoephedrine HCl
Advil Cold and Sinus Nighttimeibuprofen + pseudoephedrine HCll + chlorpheniramine maleate
Advil Cold and Sinus Plusibuprofen + pseudoephedrine HCl + chlorpheniramine maleate
Advil Flu & Body Acheibuprofen + pseudoephedrine HCl
Children's Advil Coldibuprofen + pseudoephedrine HCl
Dristan Sinus Capletsibuprofen + pseudoephedrine HCl
IBUDONEHydrocodone + Ibuprofen
Motrin Children's Coldibuprofen + pseudoephedrine HCl
Motrin Sinus Headacheibuprofen + pseudoephedrine HCl
NORCOHydrocodone + Ibuprofen
REPREXAINHydrocodone + Ibuprofen
REZIRAHydrocodone + Ibuprofen
Robax Platinummethocarbamol + ibuprofen
Sudafed Sinus Advanceibuprofen + pseudoephedrine HCl
TUSSICAPSHydrocodone + Ibuprofen
Vicoprofenibuprofen + hydrocodone bitartrate
SaltsNot Available
Categories
CAS number15687-27-1
WeightAverage: 206.2808
Monoisotopic: 206.13067982
Chemical FormulaC13H18O2
InChI KeyHEFNNWSXXWATRW-UHFFFAOYSA-N
InChI
InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)
IUPAC Name
2-[4-(2-methylpropyl)phenyl]propanoic acid
SMILES
CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as phenylpropanoic acids. These are compounds with a structure containing a benzene ring conjugated to a propanoic acid.
KingdomOrganic compounds
Super ClassPhenylpropanoids and polyketides
ClassPhenylpropanoic acids
Sub ClassNot Available
Direct ParentPhenylpropanoic acids
Alternative Parents
Substituents
  • 2-phenylpropanoic-acid
  • Phenylacetate
  • Monoterpenoid
  • Monocyclic monoterpenoid
  • Aromatic monoterpenoid
  • P-cymene
  • Phenylpropane
  • Benzenoid
  • Monocyclic benzene moiety
  • Monocarboxylic acid or derivatives
  • Carboxylic acid
  • Carboxylic acid derivative
  • Hydrocarbon derivative
  • Organooxygen compound
  • Carbonyl group
  • Aromatic homomonocyclic compound
Molecular FrameworkAromatic homomonocyclic compounds
External DescriptorsNot Available
Pharmacology
IndicationFor symptomatic treatment of rheumatoid arthritis, juvenile rheumatoid arthritis and osteoarthritis. May be used to treat mild to moderate pain and for the management of dysmenorrhea. May be used to reduce fever. Has been used with some success for treating ankylosing spondylitis, gout and psoriatic arthritis. May reduce pain, fever and inflammation of pericarditis. May be used IV with opiates to relieve moderate to severe pain. Ibuprofen lysine may be used IV to treat patent ductus arteriosus (PDA) in premature neonates.
PharmacodynamicsIbuprofen is a nonsteroidal anti-inflammatory agent (NSAIA) or nonsteroidal anti-inflammatory drug (NSAID), with analgesic and antipyretic properties. Ibuprofen has pharmacologic actions similar to those of other prototypical NSAIAs, which are thought to act through inhibition of prostaglandin synthesis.
Mechanism of actionThe exact mechanism of action of ibuprofen is unknown. Ibuprofen is a non-selective inhibitor of cyclooxygenase, an enzyme invovled in prostaglandin synthesis via the arachidonic acid pathway. Its pharmacological effects are believed to be due to inhibition cylooxygenase-2 (COX-2) which decreases the synthesis of prostaglandins involved in mediating inflammation, pain, fever and swelling. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation. Inhibition of COX-1 is thought to cause some of the side effects of ibuprofen including GI ulceration. Ibuprofen is administered as a racemic mixture. The R-enantiomer undergoes extensive interconversion to the S-enantiomer in vivo. The S-enantiomer is believed to be the more pharmacologically active enantiomer.
Absorption~ 80% absorbed from GI tract

Time to reach peak plasma concentration = 47 minutes (suspension), 62 minutes (chewable tablets), 120 minutes (conventional tablets)

Volume of distributionNot Available
Protein binding90-99% to whole human plasma and site II of purified albumin, binding appears to be saturable and becomes non-linear at concentrations exceeding 20 mcg/ml.
Metabolism

R-enanatiomer undergoes extensive enantiomeric conversion (53-65%) to the more active S-enantiomer in vivo. Metablized by oxidation to 2 inactive metabolites: (+)-2[4´-(2-hydroxy-2-methylpropyl)phenyl]propionic acid and (+)-2-[4´-(2-carboxypropyl)phenyl]propionic acid. Very small amounts of 1-hydroxyibuprofen and 3-hydroxyibuprofen have been recovered from urine. Cytochrome P450 2C9 is the major catalyst in the formation of oxidative metabolites. Oxidative metabolites may be conjugated to glucuronide prior to excretion.

SubstrateEnzymesProduct
Ibuprofen
Ibuprofen glucuronideDetails
Ibuprofen
2-HydroxyibuprofenDetails
Ibuprofen
3-HydroxyibuprofenDetails
Ibuprofen
Not Available
1-hydroxyibuprofenDetails
3-Hydroxyibuprofen
Carboxy-ibuprofenDetails
Route of eliminationIbuprofen is rapidly metabolized and eliminated in the urine.
Half life2-4 hours
ClearanceNot Available
Toxicity

Side effects: May cause peripheral edema and fluid retention. Use caution in patients with congestive heart failure or severe uncontrolled hypertension. May cause dyspepsia, heartburn, nausea, vomiting, anorexia, diarrhea, constipation, stomatitis, flatulence, bloating, epigastric pain, and abdominal pain. Peptic ulcer and GI bleeding have been reported. May also cause dizziness, headache and nervousness. Acute renal failure accompanied by acute tubular necrosis has been reported.

Most common symptoms of overdose are abdominal pain, nausea, vomiting, lethargy, vertigo, drowsiness (somnolence), dizziness and insomnia. Other symptoms of overdose include headache, loss of consciousness, tinnitus, CNS depression, convulsions and seizures. May rarely cause metabolic acidosis, abnormal hepatic function, hyperkalemia, renal failure, dyspnea, respiratory depression, coma, acute renal failure, and apnea (primarily in very young pediatric patients).

LD50=1255mg/kg(orally in mice)

Affected organisms
  • Humans and other mammals
Pathways
PathwayCategorySMPDB ID
Ibuprofen Metabolism PathwayDrug metabolismSMP00590
Ibuprofen Action PathwayDrug actionSMP00086
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9927
Blood Brain Barrier+0.9619
Caco-2 permeable+0.8866
P-glycoprotein substrateNon-substrate0.759
P-glycoprotein inhibitor INon-inhibitor0.9705
P-glycoprotein inhibitor IINon-inhibitor0.9323
Renal organic cation transporterNon-inhibitor0.9323
CYP450 2C9 substrateNon-substrate0.7594
CYP450 2D6 substrateNon-substrate0.9116
CYP450 3A4 substrateNon-substrate0.6877
CYP450 1A2 substrateNon-inhibitor0.9045
CYP450 2C9 substrateNon-inhibitor0.9305
CYP450 2D6 substrateNon-inhibitor0.9231
CYP450 2C19 substrateNon-inhibitor0.9881
CYP450 3A4 substrateNon-inhibitor0.9655
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9691
Ames testNon AMES toxic0.9894
CarcinogenicityCarcinogens 0.5553
BiodegradationReady biodegradable0.5142
Rat acute toxicity2.3092 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9719
hERG inhibition (predictor II)Non-inhibitor0.9734
Pharmacoeconomics
ManufacturersNot Available
Packagers
Dosage forms
FormRouteStrength
Capsuleoral200 mg
Capsule, coatedoral200 mg
Capsule, liquid filledoral200 mg
Capsule, liquid filledoral220 mg
Injectionintravenous100 mg/mL
Liquidoral100 mg/5mL
Liquidoral50 mg/1.25mL
Solutionintravenous10 mg/mL
Solutionoral100 mg/5mL
Suspensionoral100 mg/5mL
Suspensionoral200 mg/10mL
Suspensionoral50 mg/1.25mL
Suspension/ dropsoral50 mg/1.25mL
Tabletoral100 mg
Tabletoral200 mg
Tabletoral400 mg
Tabletoral400 mg/537mg
Tabletoral600 mg
Tabletoral800 1
Tabletoral800 mg
Tablet, chewableoral100 mg
Tablet, coatedoral100 mg
Tablet, coatedoral200 mg
Tablet, coatedoral256 mg
Tablet, coatedoral262 mg
Tablet, coatedoral400 mg
Tablet, coatedoral600 mg
Tablet, coatedoral800 mg
Tablet, film coatedoral200 mg
Tablet, film coatedoral400 mg
Tablet, film coatedoral400 mg/301
Tablet, film coatedoral600 mg
Tablet, film coatedoral800 mg
Tablet, sugar coatedoral200 mg
Prices
Unit descriptionCostUnit
Neoprofen 20 mg/2 ml vial304.5USD ml
Caldolor 400 mg/4 ml vial2.21USD ml
Caldolor 800 mg/8 ml vial1.58USD ml
Nuprin arthritis patch1.11USD patch
Ibuprofen powder1.04USD g
Nuprin muscle & joint patch1.03USD patch
Profen II 45-800 mg 12 Hour tablet0.69USD tablet
Motrin 800 mg tablet0.59USD tablet
Advil allergy sinus caplet0.5USD caplet
Ibu-drops 40 mg/ml suspension drops0.42USD ml
Motrin 600 mg tablet0.4USD tablet
Ibuprofen 800 mg tablet0.36USD tablet
Ibuprofen 400 mg tablet0.35USD tablet
Infant's motrin 50 mg/1.25 ml0.34USD ml
Childs ibuprofen susp drp0.33USD ml
Ibuprofen 600 mg tablet0.33USD tablet
Wal-profen cold & sinus cplt0.3USD caplet
Infant ibuprofen susp drop0.29USD ml
Motrin 400 mg tablet0.29USD tablet
CVS Pharmacy infant ibuprofen susp drop0.25USD ml
Infants medi-profen susp0.23USD ml
Advil cold & sinus caplet0.22USD caplet
Advil pm caplet0.22USD caplet
Soba profen cold-sinus tablet0.22USD tablet
Midol caplet0.21USD caplet
Advil migraine 200 mg capsule0.2USD capsule
Ibuprofen cold-sinus caplet0.2USD caplet
Motrin 100 mg caplet0.2USD caplet
Motrin pm caplet0.2USD caplet
Advil 200 mg liqui-gel capsule0.19USD capsule
Soba profen ib caplet0.19USD caplet
Motrin 100 mg tablet chew0.18USD tablet
Pub infants profenib drops0.18USD ml
Sm ibuprofen ib 100 mg tablet0.18USD tablet
Eck ibuprofen jr caplet0.17USD caplet
Ibuprofen pm caplet0.17USD caplet
Advil 200 mg caplet0.15USD capsule
Advil 200 mg gel caplet0.15USD caplet
Advil 200 mg tablet0.15USD tablet
Ibuprofen 100 mg tablet chew0.15USD tablet
Motrin ib 200 mg caplet0.15USD caplet
Apo-Ibuprofen 600 mg Tablet0.14USD tablet
CVS Pharmacy ibuprofen jr str 100 mg tablet0.14USD tablet
Nu-Ibuprofen 600 mg Tablet0.14USD tablet
Motrin ib 200 mg tablet0.13USD tablet
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CVS Pharmacy ibuprofen 200 mg tablet0.05USD tablet
Ibuprofen cold suspension0.05USD ml
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Novo-Profen 600 mg Tablet0.05USD tablet
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Patents
CountryPatent NumberApprovedExpires (estimated)
United States52157551993-06-012010-06-01
United States67272862001-11-272021-11-27
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point75-77.5U.S. Patent 3,228,831 U.S. Patent 3,385,886
water solubility21 mg/L (at 25 °C)YALKOWSKY,SH & DANNENFELSER,RM (1992)
logP3.97AVDEEF,A (1997)
logS-3.99ADME Research, USCD
Caco2 permeability-4.28ADME Research, USCD
pKa4.91SANGSTER (1994)
Predicted Properties
PropertyValueSource
Water Solubility0.0684 mg/mLALOGPS
logP3.5ALOGPS
logP3.84ChemAxon
logS-3.5ALOGPS
pKa (Strongest Acidic)4.85ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area37.3 Å2ChemAxon
Rotatable Bond Count4ChemAxon
Refractivity60.73 m3·mol-1ChemAxon
Polarizability23.76 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Download (11.4 KB)
SpectraGC-MSMS/MSMS1D NMR2D NMR
References
Synthesis Reference

http://en.wikipedia.org/wiki/Ibuprofen#Synthesis

General Reference
  1. Zawada ET Jr: Renal consequences of nonsteroidal antiinflammatory drugs. Postgrad Med. 1982 May;71(5):223-30. Pubmed
  2. Townsend KP, Pratico D: Novel therapeutic opportunities for Alzheimer’s disease: focus on nonsteroidal anti-inflammatory drugs. FASEB J. 2005 Oct;19(12):1592-601. Pubmed
  3. Chen H, Jacobs E, Schwarzschild MA, McCullough ML, Calle EE, Thun MJ, Ascherio A: Nonsteroidal antiinflammatory drug use and the risk for Parkinson’s disease. Ann Neurol. 2005 Dec;58(6):963-7. Pubmed
  4. Geisslinger G, Dietzel K, Bezler H, Nuernberg B, Brune K: Therapeutically relevant differences in the pharmacokinetical and pharmaceutical behavior of ibuprofen lysinate as compared to ibuprofen acid. Int J Clin Pharmacol Ther Toxicol. 1989 Jul;27(7):324-8. Pubmed
  5. Bergner T, Przybilla B: Photosensitization caused by ibuprofen. J Am Acad Dermatol. 1992 Jan;26(1):114-6. Pubmed
  6. Dill J, Patel AR, Yang XL, Bachoo R, Powell CM, Li S: A molecular mechanism for ibuprofen-mediated RhoA inhibition in neurons. J Neurosci. 2010 Jan 20;30(3):963-72. doi: 10.1523/JNEUROSCI.5045-09.2010. Pubmed
External Links
ATC CodesC01EB16G02CC01M01AE01M02AA13
AHFS Codes
  • 28:08.04.92
PDB EntriesNot Available
FDA labelDownload (1.77 MB)
MSDSDownload (73.5 KB)
Interactions
Drug Interactions
Drug
AcebutololRisk of inhibition of renal prostaglandins
AcenocoumarolThe NSAID, ibuprofen, may increase the anticoagulant effect of acenocoumarol.
Acetylsalicylic acidConcomitant therapy of the NSAID, ketoprofen, and acetylsalicylic acid may result in additive adverse/toxic effects (e.g. GI bleeding). The NSAID may also limit the cardioprotective effect of acetylsalicylic acid. Occasional concomitant use may not cause clinically significant problems, but regular, frequent concomitant therapy is not recommended.
AlendronateIncreased risk of gastric toxicity
AnisindioneThe NSAID, ibuprofen, may increase the anticoagulant effect of anisindione.
AtenololRisk of inhibition of renal prostaglandins
Azilsartan medoxomilIncreases toxicity of each. May deteriorate renal function, particularly in volume depleted or elderly patients. Decreases effects of azilsartan by antagonism.
BetaxololNonsteroidal Anti-Inflammatory Agents such as ibuprofen may diminish the antihypertensive effect of Beta-Blockers such as betaxolol. Monitor for increases in blood pressure if a nonsteroidal anti-inflammatory agent (NSAID) is initiated/dose increased, or decreases in blood pressure if a NSAID is discontinued/dose decreased; this is particularly important if NSAID treatment is for extended periods of time. Ophthalmic beta-blockers are likely of little concern.
BevantololRisk of inhibition of renal prostaglandins
BisoprololRisk of inhibition of renal prostaglandins
BumetanideThe NSAID, ibuprofen, may antagonize the diuretic and antihypertensive effects of the loop diuretic, bumetanide.
CarteololRisk of inhibition of renal prostaglandins
CarvedilolRisk of inhibition of renal prostaglandins
ColesevelamBile acid sequestrants may decrease the absorption of Nonsteroidal Anti-Inflammatory Agents. Monitor for decreased serum concentrations/therapeutic effects of nonsteroidal anti-inflammatory agents (NSAID) if coadministered with bile acid sequestrants. Separating the administration of doses by 2 or more hours may reduce (but not eliminate) the risk of interaction. The manufacturer of colesevelam recommends that drugs should be administered at least 1 hour before or 4 hours after colesevelam.
CyclosporineMonitor for nephrotoxicity
DicoumarolThe NSAID, ibuprofen, may increase the anticoagulant effect of dicumarol.
EltrombopagIncreases levels of Ibuprofen via metabolism decrease. UDP-glucuronosyltransferase inhibition with unclear significance.
EsmololRisk of inhibition of renal prostaglandins
Ethacrynic acidThe NSAID, ibuprofen, may antagonize the diuretic and antihypertensive effects of the loop diuretic, ethacrynic acid.
FurosemideThe NSAID, ibuprofen, may antagonize the diuretic and antihypertensive effects of the loop diuretic, furosemide.
Ginkgo bilobaAdditive anticoagulant/antiplatelet effects may increase bleed risk. Concomitant therapy should be avoided.
HomoharringtonineAvoid combination with ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) due to the potential enhancement of homoharringtonine associated bleeding-related adverse effects. Specifically it is suggested to avoid this combination in patients with a platelet count of less than 50,000/uL.
LabetalolRisk of inhibition of renal prostaglandins
LithiumThe NSAID, ibuprofen, may decrease the renal excretion of lithium. Increased risk of lithium toxicity.
MethotrexateThe NSAID, ibuprofen, may decrease the renal excretion of methotrexate. Increased risk of methotrexate toxicity.
MetoprololRisk of inhibition of renal prostaglandins
NadololRisk of inhibition of renal prostaglandins
OxprenololRisk of inhibition of renal prostaglandins
PenbutololRisk of inhibition of renal prostaglandins
PindololRisk of inhibition of renal prostaglandins
PractololRisk of inhibition of renal prostaglandins
PralatrexateNSAIDs increase the risk of toxicity due to impairment of renal clearance of pralatrexate thus increasing exposure. Monitor for adverse effects or adjust dose of pralatrexate.
PrasugrelCoadministration with NSAIDS used chronically may increase the risk of bleeding.
PropranololRisk of inhibition of renal prostaglandins
SotalolRisk of inhibition of renal prostaglandins
TamoxifenIbuprofen may reduce clearance rate of Tamoxifen. Monitor for changes in therapeutic/adverse effects of Tamoxifen if Ibuprofen is initiated, discontinued or dose changed.
TolbutamideIbuprofen, a strong CYP2C9 inhibitor, may decrease the metabolism and clearance of Tolbutamide, a CYP2C9 substrate. Consider alternate therapy or monitor for changes in Tolbutamide therapeutic and adverse effects if Ibuprofen is initiated, discontinued or dose changed.
TorasemideThe NSAID, ibuprofen, may decrease the diuretic and antihypertensive effect of the loop diuretic, torasemide.
TrandolaprilThe NSAID, Ibuprofen, may reduce the antihypertensive effect of Trandolapril. Consider alternate therapy or monitor for changes in Trandolapril efficacy if Ibuprofen is initiated, discontinued or dose changed.
TreprostinilThe prostacyclin analogue, Treprostinil, may increase the risk of bleeding when combined with the NSAID, Ibuprofen. Monitor for increased bleeding during concomitant thearpy.
TriflusalThe metabolite of triflusal, 2-hydroxy-4-trifluoro-methyl-benzoic acid (HTB), impairs the serum protein binding of ibuprofen to the same extent as acetylsalisylic acid. Thus, the free fraction of glisentide may be increased. A dosage reduction may be required if used in combination.
TrimethoprimThe strong CYP2C9 inhibitor, Ibuprofen, may decrease the metabolism and clearance of Trimethoprim, a CYP2C9 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Trimethoprim if Ibuprofen is initiated, discontinued or dose changed.
VilazodoneIncreased risk of bleeding with concomitant use of non-steroidal anti-inflammatory drugs with vilazodone.
VoriconazoleIbuprofen, a strong CYP2C9 inhibitor, may increase the serum concentration of voriconazole by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects of voriconazole if ibuprofen is initiated, discontinued or dose changed.
WarfarinIbuprofen, a strong CYP2C9 inhibitor, may decrease the metabolism of warfarin. The antiplatelet effect of ibuprofen may also increase the bleed risk associated with warfarin. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of warfarin if ibuprofen is initiated, discontinued or dose changed.
Food Interactions
  • Avoid alcohol
  • Food delays the time to reach peak plasma concentrations by 30-60 minutes and reduces peak plasma concentrations by 30-50%. Extent of absorption is unaffected.
  • Take with food to reduce gastric irritation.

Targets

1. Prostaglandin G/H synthase 2

Kind: protein

Organism: Human

Pharmacological action: yes

Actions: inhibitor

Components

Name UniProt ID Details
Prostaglandin G/H synthase 2 P35354 Details

References:

  1. Chavez ML, DeKorte CJ: Valdecoxib: a review. Clin Ther. 2003 Mar;25(3):817-51. Pubmed
  2. Ouellet M, Falgueyret JP, Percival MD: Detergents profoundly affect inhibitor potencies against both cyclo-oxygenase isoforms. Biochem J. 2004 Feb 1;377(Pt 3):675-84. Pubmed
  3. Gallego-Sandin S, Novalbos J, Rosado A, Gisbert JP, Galvez-Mugica MA, Garcia AG, Pajares JM, Abad-Santos F: Effect of ibuprofen on cyclooxygenase and nitric oxide synthase of gastric mucosa: correlation with endoscopic lesions and adverse reactions. Dig Dis Sci. 2004 Sep;49(9):1538-44. Pubmed
  4. Murphey LJ, Williams MK, Sanchez SC, Byrne LM, Csiki I, Oates JA, Johnson DH, Morrow JD: Quantification of the major urinary metabolite of PGE2 by a liquid chromatographic/mass spectrometric assay: determination of cyclooxygenase-specific PGE2 synthesis in healthy humans and those with lung cancer. Anal Biochem. 2004 Nov 15;334(2):266-75. Pubmed
  5. Sanchez-Fidalgo S, Martin-Lacave I, Illanes M, Motilva V: Angiogenesis, cell proliferation and apoptosis in gastric ulcer healing. Effect of a selective cox-2 inhibitor. Eur J Pharmacol. 2004 Nov 28;505(1-3):187-94. Pubmed
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. Pubmed

2. Prostaglandin G/H synthase 1

Kind: protein

Organism: Human

Pharmacological action: yes

Components

Name UniProt ID Details
Prostaglandin G/H synthase 1 P23219 Details

References:

  1. Chavez ML, DeKorte CJ: Valdecoxib: a review. Clin Ther. 2003 Mar;25(3):817-51. Pubmed
  2. Patrignani P: Aspirin insensitive eicosanoid biosynthesis in cardiovascular disease. Thromb Res. 2003 Jun 15;110(5-6):281-6. Pubmed
  3. Gupta K, Kaub CJ, Carey KN, Casillas EG, Selinsky BS, Loll PJ: Manipulation of kinetic profiles in 2-aryl propionic acid cyclooxygenase inhibitors. Bioorg Med Chem Lett. 2004 Feb 9;14(3):667-71. Pubmed
  4. Martic M, Tatic I, Markovic S, Kujundzic N, Kostrun S: Synthesis, biological activity and molecular modeling studies of novel COX-1 inhibitors. Eur J Med Chem. 2004 Feb;39(2):141-51. Pubmed
  5. Hillarp A: [Acetylsalicylic acid resistance—clinical diagnosis with unclear mechanism] Lakartidningen. 2004 Nov 4;101(45):3504-6, 3508-9. Pubmed
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. Pubmed
  7. Yu L, Shi D, Ma L, Zhou Q, Zeng S: Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87. doi: 10.1002/bdd.1842. Epub 2013 Jun 3. Pubmed
  8. Yu L, Shi D, Ma L, Zhou Q, Zeng S: Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87. doi: 10.1002/bdd.1842. Epub 2013 Jun 3. Pubmed
  9. Yu L, Shi D, Ma L, Zhou Q, Zeng S: Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87. doi: 10.1002/bdd.1842. Epub 2013 Jun 3. Pubmed
  10. Yu L, Shi D, Ma L, Zhou Q, Zeng S: Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87. doi: 10.1002/bdd.1842. Epub 2013 Jun 3. Pubmed
  11. Yu L, Shi D, Ma L, Zhou Q, Zeng S: Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87. doi: 10.1002/bdd.1842. Epub 2013 Jun 3. Pubmed
  12. Yu L, Shi D, Ma L, Zhou Q, Zeng S: Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87. doi: 10.1002/bdd.1842. Epub 2013 Jun 3. Pubmed
  13. Yu L, Shi D, Ma L, Zhou Q, Zeng S: Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87. doi: 10.1002/bdd.1842. Epub 2013 Jun 3. Pubmed
  14. Yu L, Shi D, Ma L, Zhou Q, Zeng S: Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87. doi: 10.1002/bdd.1842. Epub 2013 Jun 3. Pubmed
  15. Yu L, Shi D, Ma L, Zhou Q, Zeng S: Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87. doi: 10.1002/bdd.1842. Epub 2013 Jun 3. Pubmed
  16. Yu L, Shi D, Ma L, Zhou Q, Zeng S: Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87. doi: 10.1002/bdd.1842. Epub 2013 Jun 3. Pubmed
  17. Yu L, Shi D, Ma L, Zhou Q, Zeng S: Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87. doi: 10.1002/bdd.1842. Epub 2013 Jun 3. Pubmed

3. Apoptosis regulator Bcl-2

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: modulator

Components

Name UniProt ID Details
Apoptosis regulator Bcl-2 P10415 Details

References:

  1. Palayoor ST, J-Aryankalayil M, Makinde AY, Cerna D, Falduto MT, Magnuson SR, Coleman CN: Gene expression profile of coronary artery cells treated with nonsteroidal anti-inflammatory drugs reveals off-target effects. J Cardiovasc Pharmacol. 2012 Jun;59(6):487-99. doi: 10.1097/FJC.0b013e31824ba6b5. Pubmed

4. Thrombomodulin

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: modulator

Components

Name UniProt ID Details
Thrombomodulin P07204 Details

References:

  1. Palayoor ST, J-Aryankalayil M, Makinde AY, Cerna D, Falduto MT, Magnuson SR, Coleman CN: Gene expression profile of coronary artery cells treated with nonsteroidal anti-inflammatory drugs reveals off-target effects. J Cardiovasc Pharmacol. 2012 Jun;59(6):487-99. doi: 10.1097/FJC.0b013e31824ba6b5. Pubmed

5. Tissue-type plasminogen activator

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: negative modulator

Components

Name UniProt ID Details
Tissue-type plasminogen activator P00750 Details

References:

  1. Palayoor ST, J-Aryankalayil M, Makinde AY, Cerna D, Falduto MT, Magnuson SR, Coleman CN: Gene expression profile of coronary artery cells treated with nonsteroidal anti-inflammatory drugs reveals off-target effects. J Cardiovasc Pharmacol. 2012 Jun;59(6):487-99. doi: 10.1097/FJC.0b013e31824ba6b5. Pubmed

6. Fatty acid-binding protein, intestinal

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: binder

Components

Name UniProt ID Details
Fatty acid-binding protein, intestinal P12104 Details

References:

  1. Velkov T, Chuang S, Wielens J, Sakellaris H, Charman WN, Porter CJ, Scanlon MJ: The interaction of lipophilic drugs with intestinal fatty acid-binding protein. J Biol Chem. 2005 May 6;280(18):17769-76. Epub 2005 Feb 18. Pubmed

7. Peroxisome proliferator-activated receptor gamma

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: activator

Components

Name UniProt ID Details
Peroxisome proliferator-activated receptor gamma P37231 Details

References:

  1. Dill J, Patel AR, Yang XL, Bachoo R, Powell CM, Li S: A molecular mechanism for ibuprofen-mediated RhoA inhibition in neurons. J Neurosci. 2010 Jan 20;30(3):963-72. doi: 10.1523/JNEUROSCI.5045-09.2010. Pubmed

8. Cystic fibrosis transmembrane conductance regulator

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Cystic fibrosis transmembrane conductance regulator P13569 Details

References:

  1. Devor DC, Schultz BD: Ibuprofen inhibits cystic fibrosis transmembrane conductance regulator-mediated Cl- secretion. J Clin Invest. 1998 Aug 15;102(4):679-87. Pubmed

Enzymes

1. Cytochrome P450 2C9

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate inhibitor

Components

Name UniProt ID Details
Cytochrome P450 2C9 P11712 Details

References:

  1. Mo SL, Zhou ZW, Yang LP, Wei MQ, Zhou SF: New insights into the structural features and functional relevance of human cytochrome P450 2C9. Part I. Curr Drug Metab. 2009 Dec;10(10):1075-126. Pubmed
  2. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. Pubmed
  3. Flockhart DA. Drug Interactions: Cytochrome P450 Drug Interaction Table. Indiana University School of Medicine (2007). Accessed May 28, 2010.
  4. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed
  5. Carlile DJ, Hakooz N, Bayliss MK, Houston JB: Microsomal prediction of in vivo clearance of CYP2C9 substrates in humans. Br J Clin Pharmacol. 1999 Jun;47(6):625-35. Pubmed

2. Cytochrome P450 2C8

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
Cytochrome P450 2C8 P10632 Details

References:

  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed
  2. Yu L, Shi D, Ma L, Zhou Q, Zeng S: Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87. doi: 10.1002/bdd.1842. Epub 2013 Jun 3. Pubmed

3. Cytochrome P450 2C19

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
Cytochrome P450 2C19 P33261 Details

References:

  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed

4. UDP-glucuronosyltransferase 1-1

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
UDP-glucuronosyltransferase 1-1 P22309 Details

References:

  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. Pubmed

5. UDP-glucuronosyltransferase 1-3

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
UDP-glucuronosyltransferase 1-3 P35503 Details

References:

  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. Pubmed

6. UDP-glucuronosyltransferase 1-9

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
UDP-glucuronosyltransferase 1-9 O60656 Details

References:

  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. Pubmed

7. UDP-glucuronosyltransferase 2B4

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
UDP-glucuronosyltransferase 2B4 P06133 Details

References:

  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. Pubmed

8. UDP-glucuronosyltransferase 2B7

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
UDP-glucuronosyltransferase 2B7 P16662 Details

References:

  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. Pubmed

9. Prostaglandin G/H synthase 1

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Prostaglandin G/H synthase 1 P23219 Details

References:

  1. Palayoor ST, J-Aryankalayil M, Makinde AY, Cerna D, Falduto MT, Magnuson SR, Coleman CN: Gene expression profile of coronary artery cells treated with nonsteroidal anti-inflammatory drugs reveals off-target effects. J Cardiovasc Pharmacol. 2012 Jun;59(6):487-99. doi: 10.1097/FJC.0b013e31824ba6b5. Pubmed

10. Prostaglandin G/H synthase 2

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Prostaglandin G/H synthase 2 P35354 Details

References:

  1. Palayoor ST, J-Aryankalayil M, Makinde AY, Cerna D, Falduto MT, Magnuson SR, Coleman CN: Gene expression profile of coronary artery cells treated with nonsteroidal anti-inflammatory drugs reveals off-target effects. J Cardiovasc Pharmacol. 2012 Jun;59(6):487-99. doi: 10.1097/FJC.0b013e31824ba6b5. Pubmed

Carriers

1. Serum albumin

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Serum albumin P02768 Details

References:

  1. Yamasaki K, Rahman MH, Tsutsumi Y, Maruyama T, Ahmed S, Kragh-Hansen U, Otagiri M: Circular dichroism simulation shows a site-II-to-site-I displacement of human serum albumin-bound diclofenac by ibuprofen. AAPS PharmSciTech. 2000 May 14;1(2):E12. Pubmed
  2. Galantini L, Leggio C, Konarev PV, Pavel NV: Human serum albumin binding ibuprofen: a 3D description of the unfolding pathway in urea. Biophys Chem. 2010 Apr;147(3):111-22. doi: 10.1016/j.bpc.2010.01.002. Epub 2010 Jan 18. Pubmed

Transporters

1. Solute carrier organic anion transporter family member 2B1

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
Solute carrier organic anion transporter family member 2B1 O94956 Details

References:

  1. Satoh H, Yamashita F, Tsujimoto M, Murakami H, Koyabu N, Ohtani H, Sawada Y: Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos. 2005 Apr;33(4):518-23. Epub 2005 Jan 7. Pubmed

2. Multidrug resistance protein 1

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
Multidrug resistance protein 1 P08183 Details

References:

  1. Faassen F, Vogel G, Spanings H, Vromans H: Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs. Int J Pharm. 2003 Sep 16;263(1-2):113-22. Pubmed

3. Multidrug resistance-associated protein 4

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Multidrug resistance-associated protein 4 O15439 Details

References:

  1. Reid G, Wielinga P, Zelcer N, van der Heijden I, Kuil A, de Haas M, Wijnholds J, Borst P: The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9244-9. Epub 2003 Jun 30. Pubmed

4. Multidrug resistance-associated protein 1

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Multidrug resistance-associated protein 1 P33527 Details

References:

  1. Reid G, Wielinga P, Zelcer N, van der Heijden I, Kuil A, de Haas M, Wijnholds J, Borst P: The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9244-9. Epub 2003 Jun 30. Pubmed

5. Solute carrier organic anion transporter family member 1A2

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Solute carrier organic anion transporter family member 1A2 P46721 Details

References:

  1. Shitara Y, Sugiyama D, Kusuhara H, Kato Y, Abe T, Meier PJ, Itoh T, Sugiyama Y: Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport. Pharm Res. 2002 Feb;19(2):147-53. Pubmed

6. Solute carrier family 22 member 6

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Solute carrier family 22 member 6 Q4U2R8 Details

References:

  1. Mulato AS, Ho ES, Cihlar T: Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1. J Pharmacol Exp Ther. 2000 Oct;295(1):10-5. Pubmed
  2. Takeda M, Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71. Pubmed
  3. Uwai Y, Saito H, Inui K: Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter. Eur J Pharmacol. 2000 Dec 1;409(1):31-6. Pubmed
  4. Apiwattanakul N, Sekine T, Chairoungdua A, Kanai Y, Nakajima N, Sophasan S, Endou H: Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Mol Pharmacol. 1999 May;55(5):847-54. Pubmed

7. Solute carrier family 22 member 8

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Solute carrier family 22 member 8 Q8TCC7 Details

References:

  1. Cha SH, Sekine T, Fukushima JI, Kanai Y, Kobayashi Y, Goya T, Endou H: Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Mol Pharmacol. 2001 May;59(5):1277-86. Pubmed
  2. Takeda M, Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71. Pubmed
  3. Kobayashi Y, Ohshiro N, Tsuchiya A, Kohyama N, Ohbayashi M, Yamamoto T: Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3. Drug Metab Dispos. 2004 May;32(5):479-83. Pubmed

8. Solute carrier family 22 member 11

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Solute carrier family 22 member 11 Q9NSA0 Details

References:

  1. Takeda M, Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71. Pubmed
  2. Cha SH, Sekine T, Kusuhara H, Yu E, Kim JY, Kim DK, Sugiyama Y, Kanai Y, Endou H: Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. J Biol Chem. 2000 Feb 11;275(6):4507-12. Pubmed

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Drug created on June 13, 2005 07:24 / Updated on September 16, 2013 17:13