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Displaying drugs 101 - 125 of 2005 in total
DrugBank ID Name Weight StructureCategoriesTherapeutic Indication
DB00511
1111-39-3
Acetyldigitoxin806.9757

C43H66O14
ThumbDigitoxin / Cardenolides / Cardiac Glycosides / Cardanolides / Steroids / Glycosides / Carbohydrates / Digitalis Glycosides / Anti-Arrhythmia Agents / Cardiotonic Agents / Cardiac Therapy / Enzyme Inhibitors / Cardiovascular Agents / Cardiovascular System / Molecular Mechanisms of Pharmacological Action / Protective Agents / Specialty Uses of Chemicals / Polycyclic Compounds / Physiological Effects of Drugs / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Digitalis glycosidesUsed for fast digitalization in congestive heart failure.
DB00864
104987-11-3
Tacrolimus804.0182

C44H69NO12
ThumbCalcineurin Inhibitors / Agents for Dermatitis, Excluding Corticosteroids / Hyperglycemia-Associated Agents / P-glycoprotein/ABCB1 Inducers / Combined Inducers of CYP3A4 and P-glycoprotein / Immunologic Factors / Dermatologicals / Physiological Effects of Drugs / Antineoplastic and Immunomodulating Agents / Immunosuppressive Agents / Myelosuppressive Agents / Enzyme Inhibitors / Molecular Mechanisms of Pharmacological Action / P-glycoprotein/ABCB1 Substrates / Macrolides / Polyketides / Lactones / Organic Chemicals / Macrocyclic Compounds / Polycyclic Compounds / Pharmacologic Actions / Chemical Actions and Uses / Cytochrome P-450 CYP3A4 Substrates / Cytochrome P-450 CYP3A Inhibitors / P-glycoprotein/ABCB1 Inhibitors / Combined Inhibitors of CYP3A4 and P-glycoprotein / Calcineurin inhibitorsFor use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It was first app...
DB09135
107793-72-6
Ioxilan791.116

C18H24I3N3O8
ThumbContrast Media / Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media / X-Ray Contrast Media, Iodinated / Iodinated Contrast Agents / Diagnostic Uses of Chemicals / Specialty Uses of Chemicals / Pharmacologic Actions / Chemical Actions and Uses / Watersoluble, nephrotropic, low osmolar X-ray contrast mediaWhen administered intra-arterially, Ioxilan is indicated for the following diagnostic tests: cerebral arteriography (300 mgI/mL), coronary arteri...
DB09156
73334-07-3
Iopromide791.1119

C18H24I3N3O8
ThumbSpecialty Uses of Chemicals / Diagnostic Uses of Chemicals / Contrast Media / Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media / X-Ray Contrast Media, Iodinated / Iodinated Contrast Agents / Pharmacologic Actions / Chemical Actions and Uses / Watersoluble, nephrotropic, low osmolar X-ray contrast mediaIopromide, as the product Iovist, is indicated for use as an X-ray contrast agent in the following procedures: Intra-arterial digital subtraction ...
DB01578
31112-62-6
Metrizamide789.1

C18H22I3N3O8
ThumbCarbohydrates / Specialty Uses of Chemicals / Glycosides / Carboxylic Acids / Hydrocarbons, Cyclic / Hydrocarbons / Hydrocarbons, Aromatic / Benzene Derivatives / Diagnostic Uses of Chemicals / Contrast Media / Benzoates / Acids, Carbocyclic / Triiodobenzoic Acids / Iodobenzoates / Aminoglycosides / X-Ray Contrast Media, Iodinated / Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media / Pharmacologic Actions / Chemical Actions and Uses / Organic Chemicals / Watersoluble, nephrotropic, low osmolar X-ray contrast mediaMetrizamide is used for lumbar, thoracic, cervical, and total columnar myelography to determine the presence of abnormalities in the spinal column,...
DB01220
80621-81-4
Rifaximin785.8785

C43H51N3O11
ThumbGastrointestinal Agents / Dermatologicals / Antidiarrheals, Intestinal Antiinflammatory/antiinfective Agents / Antibiotics for Topical Use / Intestinal Antiinfectives / Nucleic Acid Synthesis Inhibitors / Alimentary Tract and Metabolism / Cytochrome P-450 CYP3A Inducers / Combined Inducers of CYP3A4 and P-glycoprotein / Enzyme Inhibitors / Anti-Infective Agents / Anti-Bacterial Agents / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Other antibiotics for topical useRifaximin has multiple indications by the FDA: for the treatment of patients (≥12 years of age) with traveller's diarrhea caused by noninvasive str...
DB03147
146-14-5
Flavin adenine dinucleotide785.5497

C27H33N9O15P2
ThumbEnzymes and Coenzymes / Coenzymes / Purines / Heterocyclic Compounds, 2-Ring / Nucleic Acids, Nucleotides, and Nucleosides / Adenine Nucleotides / Ribonucleotides / Nucleotides / Purine Nucleotides / Riboflavin / Flavins / Heterocyclic Compounds, 3-Ring / Pteridines / Biological Factors / Heterocyclic Compounds / Pigments, Biological / Carbohydrates / GlycosidesUsed to treat eye diseases caused by vitamin B2 deficiency, such as keratitis and blepharitis.
DB00390
20830-75-5
Digoxin780.9385

C41H64O14
ThumbOATP1B1/SLCO1B1 Substrates / P-glycoprotein/ABCB1 Inducers / Bradycardia-Causing Agents / Specialty Uses of Chemicals / Protective Agents / Anti-Arrhythmia Agents / Cardiotonic Agents / Digitalis Glycosides / Cardiac Glycosides / Cardanolides / Cardenolides / Cardiac Therapy / Steroids / Carbohydrates / Glycosides / Polycyclic Compounds / Combined Inducers of CYP3A4 and P-glycoprotein / Enzyme Inhibitors / P-glycoprotein/ABCB1 Inhibitors / Cardiovascular Agents / Cardiovascular System / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Physiological Effects of Drugs / Cytochrome P-450 CYP3A4 Substrates / P-glycoprotein/ABCB1 Substrates / Combined Inhibitors of CYP3A4 and P-glycoprotein / Digitalis glycosidesFor the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
DB00361
71486-22-1
Vinorelbine778.9323

C45H54N4O8
ThumbRadiation-Sensitizing Agents / Antineoplastic Agents / Antineoplastic Agents, Phytogenic / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP3A Inhibitors / Antineoplastic and Immunomodulating Agents / Vinca Alkaloids and Analogues / P-glycoprotein/ABCB1 Inhibitors / Myelosuppressive Agents / Combined Inhibitors of CYP3A4 and P-glycoprotein / Cytochrome P-450 CYP2D6 Substrates / CYP2D6 Inhibitors (Weak) / Immunosuppressive Agents / Cytochrome P-450 CYP3A4 Substrates / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Vinca alkaloids and analoguesFor the treatment of non-small-cell lung carcinoma.
DB08947
60166-93-0
Iopamidol777.0853

C17H22I3N3O8
ThumbWatersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media / Pharmacologic Actions / Chemical Actions and Uses / Specialty Uses of Chemicals / Organic Chemicals / Carboxylic Acids / Hydrocarbons, Cyclic / Hydrocarbons / Hydrocarbons, Aromatic / Benzene Derivatives / Diagnostic Uses of Chemicals / Contrast Media / Benzoates / Acids, Carbocyclic / Triiodobenzoic Acids / Iodobenzoates / X-Ray Contrast Media, Iodinated / Iodinated Contrast Agents / Watersoluble, nephrotropic, low osmolar X-ray contrast media
DB00451
51-48-9
Levothyroxine776.87

C15H11I4NO4
ThumbAmino Acids, Peptides, and Proteins / Amino Acids / Amino Acids, Cyclic / Amino Acids, Aromatic / Thyroid Hormones / Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins / Thyroid Preparations / Thyroid Therapy / P-glycoprotein/ABCB1 Inducers / Thyroid Products / Combined Inducers of CYP3A4 and P-glycoprotein / Hormones / Hormones, Hormone Substitutes, and Hormone Antagonists / Cytochrome P-450 CYP2C8 Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Pharmacologic Actions / Chemical Actions and Uses / Physiological Effects of Drugs / Thyroid hormonesFor use alone or in combination with antithyroid agents to treat hypothyroidism, goiter, chronic lymphocytic thyroiditis, myxedema coma, and stupor.
DB00509
51-49-0
Dextrothyroxine776.87

C15H11I4NO4
ThumbThyroid Hormones / Hormones / Hormones, Hormone Substitutes, and Hormone Antagonists / Amino Acids, Aromatic / Amino Acids, Cyclic / Lipid Modifying Agents, Plain / Lipid Modifying Agents / Amino Acids / Amino Acids, Peptides, and Proteins / Physiological Effects of Drugs / Cardiovascular System / Pharmacologic Actions / Chemical Actions and Uses / Other lipid modifying agentsUsed to lower high cholesterol levels in the blood.
DB08818
9004-61-9
Hyaluronic acid776.6486

C28H44N2O23
ThumbPharmacologic Actions / Chemical Actions and Uses / Immunologic Factors / Physiological Effects of Drugs / Carbohydrates / Adjuvants, Immunologic / Specialty Uses of Chemicals / Protective Agents / Polysaccharides / Glycosaminoglycans / Viscoelastic Substances / Lubricants / Viscosupplements / Musculo-Skeletal System / Cicatrizants / Preparations for Treatment of Wounds and Ulcers / Dermatologicals / Nasal Preparations / Surgical Aids / Ophthalmologicals / Sensory Organs / Respiratory System / Other cicatrizants / Viscoelastic substancesUsed to treat knee pain in patients with joint inflammation (osteoarthritis). It is usually used in patients who have not responded to other treatm...
DB06441
163706-06-7
Cangrelor776.35

C17H25Cl2F3N5O12P3S2
ThumbFibrinolytic Agents / Platelet Aggregation Inhibitors / Purinergic Antagonists / Purinergic Agents / Purinergic P2 Receptor Antagonists / Purinergic P2Y Receptor Antagonists / Blood and Blood Forming Organs / Platelet Aggregation Inhibitors Excl. Heparin / Hematologic Agents / Molecular Mechanisms of Pharmacological Action / Physiological Effects of Drugs / Neurotransmitter Agents / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Platelet aggregation inhibitors excl. heparinFor use as an adjunct to percutaneous coronary intervention (PCI) for reducing the risk of periprocedural myocardial infarction (MI), repeat corona...
DB09065
1004316-88-4
Cobicistat776.03

C40H53N7O5S2
ThumbCarbamates / Acids, Acyclic / Carboxylic Acids / Thiazoles / Azoles / Heterocyclic Compounds, 1-Ring / Cytochrome P-450 Enzyme Inhibitors / Metabolic Side Effects of Drugs and Substances / Drug-Related Side Effects and Adverse Reactions / Chemically-Induced Disorders / Anti-Retroviral Agents / Anti-HIV Agents / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2D6 Inhibitors (moderate) / BCRP/ABCG2 Inhibitors / Cytochrome P-450 CYP3A4 Inhibitors (strong) / Heterocyclic Compounds / Sulfur Compounds / Inorganic Chemicals / Enzyme Inhibitors / Molecular Mechanisms of Pharmacological Action / Antiviral Agents / Direct Acting Antivirals / Antivirals for Systemic Use / Organic Chemicals / Anti-Infective Agents / Therapeutic Uses / Pharmacologic Actions / Chemical Actions and Uses / Antiinfectives for Systemic Use / Cytochrome P-450 CYP3A Inhibitors / P-glycoprotein/ABCB1 Inhibitors / Combined Inhibitors of CYP3A4 and P-glycoprotein / Antivirals for treatment of HIV infections, combinations / Antivirals for treatment of HIV infections, combinations / Antivirals for treatment of HIV infections, combinations / Other therapeutic products / Antivirals for treatment of HIV infections, combinationsCobicistat is a CYP3A inhibitor indicated to increase systemic exposure of atazanavir or darunavir (once daily dosing regimen) in combination with ...
DB09161
109581-73-9
Technetium Tc-99m sestamibi775.96

C36H66N6O6Tc
ThumbLaboratory Chemicals / Indicators and Reagents / Nitriles / Organometallic Compounds / Radiopharmaceuticals / Organotechnetium Compounds / Diagnostic Radiopharmaceuticals / Technetium (99Mtc) Compounds / P-glycoprotein/ABCB1 Substrates / Molecular Mechanisms of Pharmacological Action / Diagnostic Uses of Chemicals / Pharmacologic Actions / Chemical Actions and Uses / Specialty Uses of Chemicals / Organic Chemicals / Cardiovascular System / Technetium (99mTc) compoundsTechnetium Tc 99m Sestamibi is indicated for: 1) detecting coronary artery disease by localizing myocardial ischemia (reversible defects) and infar...
DB09374
3599-32-4
Indocyanine green774.97

C43H47N2NaO6S2
ThumbColoring Agents / Indoles / Specialty Uses of Chemicals / Chemical Actions and Uses / Heterocyclic Compounds / Heterocyclic Compounds, 2-RingNot Annotated
DB00183
5534-95-2
Pentagastrin767.9

C37H49N7O9S
ThumbProteins / Amino Acids, Peptides, and Proteins / Oligopeptides / Peptides / Peptide Hormones / Hormones / Hormones, Hormone Substitutes, and Hormone Antagonists / Neuropeptides / Nerve Tissue Proteins / Gastrointestinal Hormones / Gastrins / Diagnostic Agents / Tests for Gastric Secretion / Physiological Effects of Drugs / Pharmacologic Actions / Chemical Actions and Uses / Tests for gastric secretionUsed as a diagnostic aid for evaluation of gastric acid secretory function
DB11575
1350514-68-9
Grazoprevir766.903

C38H50N6O9S
ThumbOATP1B1/SLCO1B1 Substrates / NS3/4A Protease Inhibitors / P-glycoprotein/ABCB1 SubstratesGrazoprevir is indicated in combination with elbasvir (as the fixed dose combination product Zepatier) with or without ribavirin for treatment of c...
DB09297
1216941-48-8
Paritaprevir765.89

C40H43N7O7S
ThumbAntiviral Agents / Direct Acting Antivirals / Antivirals for Systemic Use / NS3/4A Protease Inhibitors / Antiinfectives for Systemic Use / Cytochrome P-450 CYP3A4 Substrates / Other antivirals / Other antiviralsWhen used within the fixed dose combination product of paritaprevir/ombitasvir/ritonavir (Technivie), paritaprevir is indicated in combination with...
DB01396
71-63-6
Digitoxin764.9391

C41H64O13
ThumbSpecialty Uses of Chemicals / Protective Agents / Anti-Arrhythmia Agents / Cardiotonic Agents / Digitalis Glycosides / Cardiac Glycosides / Cardanolides / Cardenolides / Cardiac Therapy / Steroids / Carbohydrates / Glycosides / Polycyclic Compounds / Enzyme Inhibitors / Cardiovascular Agents / Cardiovascular System / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Physiological Effects of Drugs / Cytochrome P-450 CYP3A4 Substrates / P-glycoprotein/ABCB1 Substrates / Digitalis glycosidesFor the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
DB05109
114899-77-3
Trabectedin761.837

C39H43N3O11S
ThumbMolecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Antineoplastic Agents / Immunosuppressive Agents / Noxae / Toxic Actions / Alkylating Agents / Antineoplastic Agents, Alkylating / Antineoplastic and Immunomodulating Agents / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP2E1 Substrates / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP2C19 Substrates / Myelosuppressive Agents / Cytochrome P-450 CYP3A4 Substrates / Other plant alkaloids and natural productsIndicated for treatment of advanced soft tissue sarcoma in patients refractory to or unsuitable to receive anthracycline or ifosfamide chemotherapy...
DB00309
53643-48-4
Vindesine753.9261

C43H55N5O7
ThumbSecologanin Tryptamine Alkaloids / Indole Alkaloids / Vinca Alkaloids / Antimitotic Agents / Mitosis Modulators / Antineoplastic Agents, Phytogenic / Tubulin Modulators / Vinca Alkaloids and Analogues / Antineoplastic Agents / Immunosuppressive Agents / Indoles / Antineoplastic and Immunomodulating Agents / Myelosuppressive Agents / Heterocyclic Compounds, 2-Ring / Molecular Mechanisms of Pharmacological Action / Heterocyclic Compounds / Alkaloids / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Cytochrome P-450 CYP3A4 Substrates / Vinca alkaloids and analoguesFor the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia and acute panmyelosis
DB06290
923604-59-5
Simeprevir749.939

C38H47N5O7S2
ThumbHeterocyclic Compounds, 3-Ring / Heterocyclic Compounds / Sulfonamides / Amides / Sulfones / Sulfur Compounds / Inorganic Chemicals / Enzyme Inhibitors / Molecular Mechanisms of Pharmacological Action / Antiviral Agents / Protease Inhibitors / Direct Acting Antivirals / Antivirals for Systemic Use / OATP1B1/SLCO1B1 Substrates / P-glycoprotein/ABCB1 Substrates / NS3/4A Protease Inhibitors / Organic Chemicals / Anti-Infective Agents / Therapeutic Uses / Pharmacologic Actions / Chemical Actions and Uses / Antiinfectives for Systemic Use / Cytochrome P-450 CYP1A2 Inhibitors / Cytochrome P-450 CYP1A2 Inhibitors (moderate) / Cytochrome P-450 CYP3A4 Substrates / P-glycoprotein/ABCB1 Inhibitors / Combined Inhibitors of CYP3A4 and P-glycoprotein / Protease inhibitorsSimeprevir is indicated in patient's with hepatitis C virus (HCV) genotype 1 for the treatment of chronic hepatitis as a combination therapy, which...
DB00207
83905-01-5
Azithromycin748.9845

C38H72N2O12
ThumbAnti-Infective Agents / Macrocyclic Compounds / Polycyclic Compounds / Anti-Bacterial Agents / Macrolides / Polyketides / Lactones / Erythromycin / Ophthalmologicals / Sensory Organs / Antibacterials for Systemic Use / Antiinfectives for Systemic Use / Antiinfectives / Macrolides, Lincosamides and Streptogramins / Cytochrome P-450 CYP2A6 Inhibitors / P-glycoprotein/ABCB1 Inhibitors / Moderate Risk QTc-Prolonging Agents / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Organic Chemicals / Cytochrome P-450 CYP1A2 Inhibitors / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP1A2 Inhibitors (moderate) / Cytochrome P-450 CYP3A4 Substrates / Combined Inhibitors of CYP3A4 and P-glycoprotein / Combinations of antibacterials / MacrolidesFor the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific condi...
Displaying drugs 101 - 125 of 2005 in total