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Displaying drugs 201 - 225 of 13643 in total

Lanolin

Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Description: … Lanolin is also frequently used in protective baby skin treatment and for sore nipples in breastfeeding ... Lanolin is a yellow fat obtained from sheep's wool. ... For this reason, it is also called wool wax or wool grease. …
Matched Mixtures name: … CVS A and D All-Purpose Skin Protectant ... Kendra SKIN PROTECTION and PAIN RELIEF FOR HAIR REMOVAL ... Skullduggery Pain Relief and Skin Protection for Tattoos …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Risankizumab

Risankizumab is a fully humanized IgG1 monoclonal antibody (mAb) directed against interleukin 23 (IL-23). It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019. Risankizumab is used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease.[L39885,L44191,L44231] Risankizumab...
Approved
Investigational
Matched Description: … [L39885,L44191,L44231] Risankizumab is being investigated for atopic dermatitis.[A254716] ... Risankizumab is a fully humanized IgG1 monoclonal antibody (mAb) directed against interleukin 23 (IL- ... [L39885] It gained its first global approval in Japan in March 2019, followed by approval in Canada, …
Matched Products: … Skyrizi 75 mg solution for injection in pre-filled syringe ... SKYRIZI SOLUTION FOR INJECTION IN PRE-FILLED PEN 150MG/ML ... SKYRIZI SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 150MG/ML …

Vecuronium

Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other...
Approved
Investigational
Matched Iupac: … ,8S,9aS,9bS,11aS)-1,7-bis(acetyloxy)-9a,11a-dimethyl-8-(piperidin-1-yl)-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. ... Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination …
Matched Products: … Vecuronium Bromide for Injection ... VECURONIUM BROMIDE FOR INJECTION ... BROCURIX 10 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …

Tenofovir alafenamide

Tenofovir alafenamide is a novel tenofovir prodrug developed in order to improve renal safety when compared to the counterpart tenofovir disoproxil. Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and intestinal...
Approved
Matched Description: … [T239] Tenofovir alafenamide is an alanine ester form characterized for presenting low systemic levels ... Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when ... of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use …

Loperamide

Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Description: … [A251610, A251625] However, loperamide is associated with a risk for experiencing a range of adverse ... [L42785] The drug was first synthesized in 1969 and used medically in 1976. ... Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating …
Matched Mixtures name: … Doc in the Box All Day Supply …
Matched Products: … A D ... Imodium A-D ... Vaprino A-D …

Tocilizumab

Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Tocilizumab was granted FDA approval on 8 January 2010 to treat a...
Approved
Matched Description: … [L12789] It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing ... [L44483] Tocilizumab-bavi, a biosimilar drug, was approved by the FDA in September 2023.[L48385] ... Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory …
Matched Categories: … Agents reducing cytokine levels ... Biologics for Rheumatoid Arthritis Treatment ... Experimental Unapproved Treatments for COVID-19 …
Matched Products: … ACTEMRA (162 MG SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE) ... ACTEMRA 162MG/0.9ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE ... Actemra 162mg Solution for Injection in Pre-filled Syringe 162mg/0.9ml …

Cantharidin

Cantharidin is a naturally occurring odorless, colorless fatty substance of the terpenoid class that is produced as an oral fluid in the alimentary canal of the male blister beetle.[A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin to a female beetle as a copulatory...
Approved
Investigational
Matched Description: … to a female beetle as a copulatory gift during mating. ... treatment for cutaneous warts since that time. ... [A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Tedizolid phosphate

Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Description: … This product is currently available as both an oral tablet and as a powder for intravenous injection. ... [A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the ... Tedizolid is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … SIVEXTRO LYOPHILIZED POWDER FOR SOLUTION FOR INFUSION 200MG PER VIAL …

Nadofaragene firadenovec

Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Description: … alternatives for the treatment of BCG-unresponsive NMIBC. ... It is the first gene therapy approved by the FDA for the treatment of bladder cancer. ... [L44381] It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin …

Insulin lispro

Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Description: … These biochemical changes result in a reduced tendency for self-association resulting in dissolution ... lower glucose levels in the blood. ... Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type …
Matched Mixtures name: … HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/ml ... HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/ml …
Matched Categories: … Drugs Used in Diabetes ... Insulins and Analogues for Injection, Fast-Acting …

Dextromethorphan

Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Description: … [A215412] Although similar in structure to other opioids, it has minimal interaction with opioid receptors ... and also a drug of abuse. ... Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant …
Matched Mixtures name: … Benylin for Children All-IN-one Cold & Fever ... Benylin for Children All-IN-one Cold and Fever ... Benylin for Children All-IN-one Cold & Fever Nightime …
Matched Products: … Creomulsion For Children ... Benylin for Children Dry Cough ... Cocoa for Children Long-acting Cough …

Aluminum chlorohydrate

Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near...
Approved
Matched Description: … It is also used as a coagulant in the water purification process. ... Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl( ... It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … A Bille ... CLARINSMEN Antiperspirant ALL DAY DRY ALCOHOL-FREE ... Lutece Creme Desodorisante A Bile 20% …

Alemtuzumab

Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a...
Approved
Investigational
Matched Description: … Alemtuzumab is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium containing ... [L43397] Alemtuzumab was approved by the FDA in 2001. ... [L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic …
Matched Products: … LEMTRADA Concentrate for Solution for Infusion 12 mg ... LEMTRADA CONCENTRATE FOR SOLUTION FOR INFUSION 12 MG/ 1.2 ML …

Ferrous sulfate anhydrous

Iron deficiency anemia is a large public health concern worldwide, especially in young children, infants, and women of childbearing age. This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support the formation of erythrocytes, also known as red blood cells. Ferrous sulfate is...
Approved
Matched Description: … [A190528] Ferrous sulfate is a synthetic agent used in the treatment of iron deficiency. ... Iron deficiency anemia is a large public health concern worldwide, especially in young children, infants ... It is the gold standard of oral iron therapy in the UK and many other countries.[L2234,L2246] …
Matched Mixtures name: … Phytofortis + Calcium A-D …
Matched Products: … FER IN SOL GOTAS …

Fludrocortisone

Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched Iupac: … 1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Fludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace ... missing endogenous corticosteroids in patients with adrenal insufficiency. ... primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a …
Matched Categories: … Corticosteroids for Systemic Use ... Corticosteroids for Systemic Use, Plain …

Fremanezumab

Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for the prevention of migraine headaches. It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. Along with other recently approved anti-CGRP therapies such as galcanezumab, erenumab, and the oral CGRP antagonist...
Approved
Investigational
Matched Description: … (CGRP) for the prevention of migraine headaches. ... Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide ... [L11749] It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. …
Matched Products: … AJOVY SOLUTION FOR INJECTION IN PRE-FILLED PEN 225 MG/1.5ML ... AJOVY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 225 MG/1.5ML …

Hypromellose

Hypromellose, or hydroxypropyl methylcellulose (HPMC) , is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations . It...
Approved
Matched Description: … of a drug in a controlled fashion, effectively increasing the duration of release of a drug to prolong ... polymer that forms a colloid solution when dissolved in water. ... Hypromellose is also found in eye drops as a lubricant [L1803]. …
Matched Mixtures name: … Rohto All-In-One ... Visine ALL DAY COMFORT DRY EYE Relief ... Visine for Dry Eye True Tears …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ranibizumab

Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology ... In order to improve drug delivery to the target organ, ranibizumab is available for intravitreal use. ... BYOOVIZ, a biosimilar of LUCENTIS, was approved by Health Canada in March 2022, making it the first and …
Matched Products: … LUCENTIS 10 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE ... LUCENTIS SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 1.65mg/0.165ml ... Lucentis 10mg/ml Solution for Injection …

Esketamine

Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness preceding suicide.[L5596,A175462] On March 5, 2019, the nasal spray drug, esketamine, also known as Spravato (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. Esketamine is the s-enantiomer of Ketamine. Ketamine...
Approved
Investigational
Matched Description: … The intranasal route of administration for this drug allows for easy administration and a fast onset ... [L5593] Esketamine may prove to be a promising treatment for patients diagnosed with major depressive ... The FDA approved ketamine (Ketalar) in 1970. …
Matched Categories: … Antidepressive Agents Indicated for Depression …
Matched Products: … Eskelan 25 mg/ml-Injektions-/Infusionslösung in Ampullen ... Eskelan 25 mg/ml-Injektionslösung in Durchstechflaschen ... Eskelan 5 mg/ml-Injektionslösung in Durchstechflaschen …

Magnesium sulfate

A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the ... It causes direct inhibition of action potentials in myometrial muscle cells. …
Matched Mixtures name: … Magnesium Sulfate In 5% Dextrose Inj(20mg/ml) ... KABIVEN EMULSION FOR INFUSION ... SmofKabiven Emulsion for Infusion …
Matched Categories: … Drugs for Constipation ... Tests for Bile Duct Patency …
Matched Products: … Magnesium Sulfate In Water for Injection ... Magnesium Sulfate in Water ... Magnesium Sulfate in Dextrose …

Alectinib

Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC cells. Inhibition of ALK...
Approved
Investigational
Matched Description: … Approved under accelerated approval in 2015, alectinib is indicated for use in patients who have progressed ... Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma ... It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Revefenacin

Revefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting muscarinic antagonists (LAMA). The labile primary amide in the structure produces a "soft-drug" site that allows rapid systemic clearance and minimizing of the systemically mediated adverse reactions. The LAMA group falls into a...
Approved
Investigational
Matched Description: … of agents are recommended as a maintenance therapy for chronic obstructive pulmonary disease (COPD). ... The labile primary amide in the structure produces a "soft-drug" site that allows rapid systemic clearance ... Revefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting …
Matched Categories: … Drugs for Obstructive Airway Diseases …

Homosalate

Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage...
Approved
Investigational
Matched Description: … It is a common ingredient in many commercially available sunscreens. ... It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol …
Matched Mixtures name: … Hope In A Jar Broad Spectrum SPF 25 Sunscreen and Moisturizer for All Skin Types ... Hope In A Jar SPF 25 ... Gloves in a Bottle with SPF15 …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ofatumumab

Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Description: … Authorization Application (MAA), respectively, for ofatumumab for the treatment of RMS in adults. ... has a higher affinity towards CD20. ... Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. …
Matched Products: … KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MG/0.4ML ... Bonspri 20mg/0.4mL Solution for Injection in Pre-filled syringe ... KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 20MG/0.4ML …

Epirubicin

An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Categories: … UGT2B7 Substrates with a Narrow Therapeutic Index …
Matched Products: … ALRUBIN® 50MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 10mg ... EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 50mg …
Displaying drugs 201 - 225 of 13643 in total