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Displaying drugs 601 - 625 of 705 in total

Atidarsagene autotemcel

Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC …
Matched Description: … authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic ... Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

(1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE

Experimental
Matched Name: … (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE …
Matched Iupac: … (2R)-1-{[(2S)-2,3-dihydroxypropyl phosphonato]oxy}-3-(pentanoyloxy)propan-2-yl octanoate …

2'-O-Methyl-3'-Methyl-3'-Deoxy-Arabinofuranosyl-Thymine-5'-Phosphate

Experimental
Matched Name: … 2'-O-Methyl-3'-Methyl-3'-Deoxy-Arabinofuranosyl-Thymine-5'-Phosphate …

Chrysoeriol

Investigational
Matched Synonyms: … 3'-o-methylluteolin ... 4h-1-benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)- …
Matched Iupac: … 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one …

Aceclofenac

Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid …
Matched Description: … , crepitus, and local inflammation [A19666]. ... modification in effort to improve the gastrointestinal tolerability of the drug. ... It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

5-methoxy-N,N-dimethyltryptamine

5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug, as well as dimethyltryptamine and bufotenin, have been registered to be used in South America in religious and spiritual rituals.
Experimental
Illicit
Matched Synonyms: … O-methylbufotenine …
Matched Description: … It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado ... America in religious and spiritual rituals. ... This drug, as well as [dimethyltryptamine] and [bufotenin], have been registered to be used in South …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Zorevunersen

Investigational
Matched Synonyms: … Rna, (p-thio)(2'-o-(2-methoxyethyl))(a-g-m5u-m5u-g-g-a-g-m5c-a-a-g-a-m5u-m5u-a-m5u-m5c) …

1-Deoxy-6-O-Phosphono-1-[(Phosphonomethyl)Amino]-L-Threo-Hexitol

Experimental
Matched Name: … 1-Deoxy-6-O-Phosphono-1-[(Phosphonomethyl)Amino]-L-Threo-Hexitol …
Matched Iupac: … {[(2R,3R,4R,5R)-2,3,4,5-tetrahydroxy-6-[(phosphonomethyl)amino]hexyl]oxy}phosphonic acid …

Panax notoginseng root

Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Synonyms: … Tienchi Ginseng (Constituent of American Ginseng, Asian Ginseng, and Tienchi Ginseng) …
Matched Description: … Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. …

Gimatecan

Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
Investigational
Matched Synonyms: … -3,14-dioxo-3,4,12,14-tetrahydro-1-H-pyrano[3',4':6,7]-indolizino-[1,2-b]-quinoline-11-carbaldehyde O- ... indolizino[1,2-b]quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-, 11-[O- …
Matched Iupac: … (19S)-10-[(1E)-[(tert-butoxy)imino]methyl]-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰ …

Caffeine

Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Description: … conditions of the premature newborn, pain relief, and to combat drowsiness. ... development and may eventually cause asthma or early onset emphysema in those born prematurely. ... [T716] Caffeine is also used in a variety of cosmetic products and can be administered topically, orally …
Matched Mixtures name: … EMOL OSK ... Midol One ... OKA GALEZ …
Matched Categories: … combinations of xanthines ... caffeine and sodium benzoate ... Respiratory and CNS Stimulants ... Caffeine and Caffeine Containing Products ... Anorexigenic Agents & Respiratory and CNS Stimulants …
Matched Products: … Caffeine and Sodium Benzoate …

Ivermectin

Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Iupac: … [15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen-2'-one ... 24'S)-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy ... -2,6'-tetracyclo[15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen-2'-one; (1'R,2R,4'S,5S ... }-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-6-(propan-2-yl)-3',7',19'-trioxaspiro[oxane ... 2-yl]-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy …
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... with statistical errors and accusations of plagiarism. ... _in vitro_ data, and the clinical utility of this data remains unclear. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... I-Dectin 0.5 % Pour-On ... Vimectin 0.5% w/v Pour On …

Omeprazole

Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Description: … characterized by the oversecretion of gastric acid. ... of many other proton pump inhibitor drugs [A174232]. ... Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults …
Matched Mixtures name: … Zegerid OTC ... Zegerid OTC ... Zegerid OTC …
Matched Categories: … Alimentary Tract and Metabolism ... Omeprazole and enantiomer ... omeprazole, amoxicillin and rifabutin ... omeprazole, amoxicillin and metronidazole ... omeprazole, amoxicillin and clarithromycin …
Matched Products: … Up and Up Omeprazole ... Berkley and Jensen Omeprazole ... Foster and Thrive Omeprazole …

Dextromethorphan

Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Description: … and also a drug of abuse. ... Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant …
Matched Mixtures name: … Cold and Flu All In One ... Meds on the Go ... Cold and Flu-IN-one Extra Strength …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... bupropion and dextromethorphan ... Heterocyclic Compounds with 4 or More Rings ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake …
Matched Products: … Up and Up Cough Suppressant DM ... Up and Up 12 Hour Cough Relief ... Foster and Thrive 12 Hour Cough Relief …

N,N-[2,5-O-Dibenzyl-glucaryl]-DI-[1-amino-indan-2-OL]

Experimental
Matched Name: … N,N-[2,5-O-Dibenzyl-glucaryl]-DI-[1-amino-indan-2-OL] …

4-[(3-BROMO-4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE

Experimental
Matched Name: … 4-[(3-BROMO-4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE …

Coagulation Factor IX Human

Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Approved
Matched Description: … Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs ... Deficiency of this protein causes hemophilia B. …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... coagulation factor IX, II, VII and X in combination …
Matched Products: … IMMUNINE 120IU/ML Powder and solvent for solution for injection or infusion …

Insulin lispro

Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Description: … Use of basal and bolus insulin together is intended to mimic the pancreas' production of endogenous insulin ... is a slowly progressing metabolic disorder caused by a combination of genetic and lifestyle factors ... ], [DB01120], or [DB01261] have been tried, and when sufficient damage has been caused to pancreatic …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen …

Sulpiride

Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Synonyms: … N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide …
Matched Description: … [A229538] Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather ... [A229683] Sulpiride is not approved by the FDA, Health Canada, or the EMA; though it is approved in …
Matched Categories: … Benzamides and benzamide derivatives …

Bosentan

Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Synonyms: … p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide …
Matched Description: … would otherwise promote narrowing of the blood vessels and lead to high blood pressure. ... Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that …
Matched Categories: … combinations of sulfonamides ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

2-(acetylamino)-2-deoxy-4-O-beta-D-galactopyranosyl-alpha-D-glucopyranose

Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-beta-D-galactopyranosyl-alpha-D-glucopyranose …
Matched Iupac: … 6R)-2,4-dihydroxy-6-(hydroxymethyl)-5-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy …

N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE

Experimental
Matched Name: … N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE …

O-(((1R)-((N-PHENYLMETHOXYCARBONYL-L-ALANYL)AMINO)ETHYL)HYDROXYPHOSPHONO)-L-BENZYLACETIC ACID

Experimental
Matched Name: … O-(((1R)-((N-PHENYLMETHOXYCARBONYL-L-ALANYL)AMINO)ETHYL)HYDROXYPHOSPHONO)-L-BENZYLACETIC ACID …
Matched Iupac: … (2S)-2-({[(1R)-1-[(2S)-2-{[(benzyloxy)carbonyl]amino}propanamido]ethyl](hydroxy)phosphoryl}oxy)-3-phenylpropanoic …

Metoclopramide

Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Synonyms: … 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide …
Matched Description: … impact on quality of life and poses a significant burden on the healthcare system. ... It is available in the oral tablet form or in solution, and can also be administered through the intravenous ... Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative …
Matched Categories: … Alimentary Tract and Metabolism ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... Benzamides and benzamide derivatives …
Matched Products: … Metozolv ODT …

Telitacicept

Investigational
Matched Synonyms: … (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 601 - 625 of 705 in total